LOCUS       DAZKNV010000001       112716 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000001 DAZKNV010000000
VERSION     DAZKNV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 112716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 112716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..112716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.001"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACG8M1_000001"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACG8M1_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFQ0420757.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACG8M1_000002"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACG8M1_000002"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFQ0420758.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACG8M1_000003"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACG8M1_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFQ0420759.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACG8M1_000004"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACG8M1_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFQ0420760.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACG8M1_000005"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACG8M1_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFQ0420761.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACG8M1_000006"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACG8M1_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFQ0420762.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="ACG8M1_000007"
     CDS             complement(8557..9027)
                     /locus_tag="ACG8M1_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFQ0420763.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="ACG8M1_000008"
     CDS             complement(9073..9498)
                     /locus_tag="ACG8M1_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFQ0420764.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="ACG8M1_000009"
     CDS             complement(9565..9834)
                     /locus_tag="ACG8M1_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFQ0420765.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="ACG8M1_000010"
     CDS             complement(9845..11440)
                     /locus_tag="ACG8M1_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0420766.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACG8M1_000011"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACG8M1_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFQ0420767.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVSDQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACG8M1_000012"
     CDS             complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACG8M1_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFQ0420768.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="ACG8M1_000013"
     CDS             15906..16880
                     /locus_tag="ACG8M1_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFQ0420769.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="ACG8M1_000014"
     CDS             17050..18450
                     /locus_tag="ACG8M1_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFQ0420770.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="ACG8M1_000015"
     CDS             complement(18528..19250)
                     /locus_tag="ACG8M1_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0420771.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="ACG8M1_000016"
     CDS             complement(19329..19835)
                     /locus_tag="ACG8M1_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0420772.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="ACG8M1_000017"
     CDS             19958..21757
                     /locus_tag="ACG8M1_000017"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFQ0420773.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21825..23399)
                     /locus_tag="ACG8M1_000018"
     CDS             complement(21825..23399)
                     /locus_tag="ACG8M1_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFQ0420774.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACG8M1_000019"
     CDS             complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACG8M1_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFQ0420775.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACG8M1_000020"
     CDS             complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACG8M1_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFQ0420776.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25176..25814)
                     /locus_tag="ACG8M1_000021"
     CDS             complement(25176..25814)
                     /locus_tag="ACG8M1_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFQ0420777.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACG8M1_000022"
     CDS             complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACG8M1_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFQ0420778.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACG8M1_000023"
     CDS             complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACG8M1_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFQ0420779.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACG8M1_000024"
     CDS             complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACG8M1_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFQ0420780.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29608..30348)
                     /locus_tag="ACG8M1_000025"
     CDS             complement(29608..30348)
                     /locus_tag="ACG8M1_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFQ0420781.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACG8M1_000026"
     CDS             complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACG8M1_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFQ0420782.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACG8M1_000027"
     CDS             complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACG8M1_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFQ0420783.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACG8M1_000028"
     CDS             complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACG8M1_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFQ0420784.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACG8M1_000029"
     CDS             complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACG8M1_000029"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFQ0420785.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACG8M1_000030"
     CDS             complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACG8M1_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFQ0420786.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACG8M1_000031"
     CDS             complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACG8M1_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFQ0420787.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37228..37512)
                     /locus_tag="ACG8M1_000032"
     CDS             complement(37228..37512)
                     /locus_tag="ACG8M1_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420788.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37530..38420)
                     /locus_tag="ACG8M1_000033"
     CDS             complement(37530..38420)
                     /locus_tag="ACG8M1_000033"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFQ0420789.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38440..38658)
                     /locus_tag="ACG8M1_000034"
     CDS             complement(38440..38658)
                     /locus_tag="ACG8M1_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFQ0420790.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38628..40328)
                     /locus_tag="ACG8M1_000035"
     CDS             complement(38628..40328)
                     /locus_tag="ACG8M1_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFQ0420791.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40595..41368
                     /locus_tag="ACG8M1_000036"
     CDS             40595..41368
                     /locus_tag="ACG8M1_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420792.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACG8M1_000037"
     CDS             complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACG8M1_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFQ0420793.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42084..42186)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42192..43163)
                     /locus_tag="ACG8M1_000038"
     CDS             complement(42192..43163)
                     /locus_tag="ACG8M1_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFQ0420794.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACG8M1_000039"
     CDS             complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACG8M1_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFQ0420795.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACG8M1_000040"
     CDS             complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACG8M1_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFQ0420796.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46118..46942)
                     /locus_tag="ACG8M1_000041"
     CDS             complement(46118..46942)
                     /locus_tag="ACG8M1_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFQ0420797.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46915..47595)
                     /locus_tag="ACG8M1_000042"
     CDS             complement(46915..47595)
                     /locus_tag="ACG8M1_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0420798.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47618..48556)
                     /locus_tag="ACG8M1_000043"
     CDS             complement(47618..48556)
                     /locus_tag="ACG8M1_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFQ0420799.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACG8M1_000044"
     CDS             complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACG8M1_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFQ0420800.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACG8M1_000045"
     CDS             complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACG8M1_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFQ0420801.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52520..53326
                     /gene="proC"
                     /locus_tag="ACG8M1_000046"
     CDS             52520..53326
                     /gene="proC"
                     /locus_tag="ACG8M1_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFQ0420802.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACG8M1_000047"
     CDS             complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACG8M1_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFQ0420803.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55372..56421)
                     /gene="recA"
                     /locus_tag="ACG8M1_000048"
     CDS             complement(55372..56421)
                     /gene="recA"
                     /locus_tag="ACG8M1_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFQ0420804.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56530..57771)
                     /locus_tag="ACG8M1_000049"
     CDS             complement(56530..57771)
                     /locus_tag="ACG8M1_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFQ0420805.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="ACG8M1_000050"
     CDS             complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="ACG8M1_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFQ0420806.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58798..59721)
                     /locus_tag="ACG8M1_000051"
     CDS             complement(58798..59721)
                     /locus_tag="ACG8M1_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFQ0420807.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60460..61746)
                     /locus_tag="ACG8M1_000052"
     CDS             complement(60460..61746)
                     /locus_tag="ACG8M1_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFQ0420808.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61739..63007)
                     /locus_tag="ACG8M1_000053"
     CDS             complement(61739..63007)
                     /locus_tag="ACG8M1_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFQ0420809.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63259..63720
                     /gene="mscL"
                     /locus_tag="ACG8M1_000054"
     CDS             63259..63720
                     /gene="mscL"
                     /locus_tag="ACG8M1_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFQ0420810.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63779..64225)
                     /locus_tag="ACG8M1_000055"
     CDS             complement(63779..64225)
                     /locus_tag="ACG8M1_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0420811.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64318..64563)
                     /locus_tag="ACG8M1_000056"
     CDS             complement(64318..64563)
                     /locus_tag="ACG8M1_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFQ0420812.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64678..65256)
                     /locus_tag="ACG8M1_000057"
     CDS             complement(64678..65256)
                     /locus_tag="ACG8M1_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0420813.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65333..65863)
                     /locus_tag="ACG8M1_000058"
     CDS             complement(65333..65863)
                     /locus_tag="ACG8M1_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFQ0420814.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65867..66727)
                     /gene="rlmB"
                     /locus_tag="ACG8M1_000059"
     CDS             complement(65867..66727)
                     /gene="rlmB"
                     /locus_tag="ACG8M1_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFQ0420815.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66720..67115)
                     /locus_tag="ACG8M1_000060"
     CDS             complement(66720..67115)
                     /locus_tag="ACG8M1_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFQ0420816.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67112..68524)
                     /gene="cysS"
                     /locus_tag="ACG8M1_000061"
     CDS             complement(67112..68524)
                     /gene="cysS"
                     /locus_tag="ACG8M1_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFQ0420817.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68521..69057)
                     /gene="epsC"
                     /locus_tag="ACG8M1_000062"
     CDS             complement(68521..69057)
                     /gene="epsC"
                     /locus_tag="ACG8M1_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFQ0420818.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69143..69382)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69379..70839)
                     /gene="gltX"
                     /locus_tag="ACG8M1_000063"
     CDS             complement(69379..70839)
                     /gene="gltX"
                     /locus_tag="ACG8M1_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFQ0420819.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71009..72166)
                     /locus_tag="ACG8M1_000064"
     CDS             complement(71009..72166)
                     /locus_tag="ACG8M1_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFQ0420820.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72200..73570)
                     /gene="radA"
                     /locus_tag="ACG8M1_000065"
     CDS             complement(72200..73570)
                     /gene="radA"
                     /locus_tag="ACG8M1_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFQ0420821.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73633..74160)
                     /locus_tag="ACG8M1_000066"
     CDS             complement(73633..74160)
                     /locus_tag="ACG8M1_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFQ0420822.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74390..75196
                     /gene="proB"
                     /locus_tag="ACG8M1_000067"
     CDS             74390..75196
                     /gene="proB"
                     /locus_tag="ACG8M1_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFQ0420823.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75193..76440
                     /locus_tag="ACG8M1_000068"
     CDS             75193..76440
                     /locus_tag="ACG8M1_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFQ0420824.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76516..76860
                     /locus_tag="ACG8M1_000069"
     CDS             76516..76860
                     /locus_tag="ACG8M1_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420825.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76977..77303)
                     /locus_tag="ACG8M1_000070"
     CDS             complement(76977..77303)
                     /locus_tag="ACG8M1_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420826.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77918..79120)
                     /locus_tag="ACG8M1_000071"
     CDS             complement(77918..79120)
                     /locus_tag="ACG8M1_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0420827.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79237..79752
                     /locus_tag="ACG8M1_000072"
     CDS             79237..79752
                     /locus_tag="ACG8M1_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0420828.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79951..80397)
                     /locus_tag="ACG8M1_000073"
     CDS             complement(79951..80397)
                     /locus_tag="ACG8M1_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFQ0420829.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80444..81922)
                     /gene="msr(C)"
                     /locus_tag="ACG8M1_000074"
     CDS             complement(80444..81922)
                     /gene="msr(C)"
                     /locus_tag="ACG8M1_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFQ0420830.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82276..82905)
                     /locus_tag="ACG8M1_000075"
     CDS             complement(82276..82905)
                     /locus_tag="ACG8M1_000075"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0420831.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82889..83353)
                     /locus_tag="ACG8M1_000076"
     CDS             complement(82889..83353)
                     /locus_tag="ACG8M1_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0420832.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83840..85108)
                     /locus_tag="ACG8M1_000077"
     CDS             complement(83840..85108)
                     /locus_tag="ACG8M1_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0420833.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85339..86076)
                     /locus_tag="ACG8M1_000078"
     CDS             complement(85339..86076)
                     /locus_tag="ACG8M1_000078"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0420834.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86143..86712)
                     /locus_tag="ACG8M1_000079"
     CDS             complement(86143..86712)
                     /locus_tag="ACG8M1_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFQ0420835.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86840..87712
                     /locus_tag="ACG8M1_000080"
     CDS             86840..87712
                     /locus_tag="ACG8M1_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0420836.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88054..88926
                     /locus_tag="ACG8M1_000081"
     CDS             88054..88926
                     /locus_tag="ACG8M1_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0420837.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88923..90881
                     /gene="nagE"
                     /locus_tag="ACG8M1_000082"
     CDS             88923..90881
                     /gene="nagE"
                     /locus_tag="ACG8M1_000082"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFQ0420838.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91213..92064)
                     /locus_tag="ACG8M1_000083"
     CDS             complement(91213..92064)
                     /locus_tag="ACG8M1_000083"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0420839.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92187..92654
                     /locus_tag="ACG8M1_000084"
     CDS             92187..92654
                     /locus_tag="ACG8M1_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFQ0420840.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92917..93399)
                     /locus_tag="ACG8M1_000085"
     CDS             complement(92917..93399)
                     /locus_tag="ACG8M1_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0420841.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93499..94362)
                     /locus_tag="ACG8M1_000086"
     CDS             complement(93499..94362)
                     /locus_tag="ACG8M1_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0420842.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94960..95835
                     /locus_tag="ACG8M1_000087"
     CDS             94960..95835
                     /locus_tag="ACG8M1_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFQ0420843.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95980..96132)
                     /locus_tag="ACG8M1_000088"
                     /pseudo
     CDS             complement(95980..96132)
                     /locus_tag="ACG8M1_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96400..97731)
                     /locus_tag="ACG8M1_000089"
     CDS             complement(96400..97731)
                     /locus_tag="ACG8M1_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0420844.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97880..98593)
                     /locus_tag="ACG8M1_000090"
     CDS             complement(97880..98593)
                     /locus_tag="ACG8M1_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0420845.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98768..100192
                     /locus_tag="ACG8M1_000091"
     CDS             98768..100192
                     /locus_tag="ACG8M1_000091"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0420846.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100491..101198
                     /locus_tag="ACG8M1_000092"
     CDS             100491..101198
                     /locus_tag="ACG8M1_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFQ0420847.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101185..101508
                     /locus_tag="ACG8M1_000093"
     CDS             101185..101508
                     /locus_tag="ACG8M1_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFQ0420848.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101597..102634)
                     /locus_tag="ACG8M1_000094"
     CDS             complement(101597..102634)
                     /locus_tag="ACG8M1_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0420849.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102955..103938)
                     /locus_tag="ACG8M1_000095"
     CDS             complement(102955..103938)
                     /locus_tag="ACG8M1_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFQ0420850.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104353..105123)
                     /locus_tag="ACG8M1_000096"
     CDS             complement(104353..105123)
                     /locus_tag="ACG8M1_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0420851.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105116..106051)
                     /locus_tag="ACG8M1_000097"
     CDS             complement(105116..106051)
                     /locus_tag="ACG8M1_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0420852.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106367..108016)
                     /locus_tag="ACG8M1_000098"
     CDS             complement(106367..108016)
                     /locus_tag="ACG8M1_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFQ0420853.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108133..110736)
                     /locus_tag="ACG8M1_000099"
     CDS             complement(108133..110736)
                     /locus_tag="ACG8M1_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFQ0420854.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110748..111798)
                     /locus_tag="ACG8M1_000100"
                     /pseudo
     CDS             complement(110748..111798)
                     /locus_tag="ACG8M1_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(111824..112138)
                     /locus_tag="ACG8M1_000101"
     CDS             complement(111824..112138)
                     /locus_tag="ACG8M1_000101"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFQ0420855.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112154..112600)
                     /locus_tag="ACG8M1_000102"
     CDS             complement(112154..112600)
                     /locus_tag="ACG8M1_000102"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFQ0420856.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
BASE COUNT        31963 a        24018 c        19969 g        36766 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta ccataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgacacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ctgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttgattaatc attcttacat gctgacagca
    21841 aagtcagggg caaaccattg aactgaacca acttttacgc tttcgcctgg ttgaggagca
    21901 tggatatatt gtcctccgcc taaagcaatc gctacgtggt aagttccgcc ttgtgacccc
    21961 cagaataaca agtctccagc ttttgcttga gaaactgaaa tttttgttcc agctgattct
    22021 tgaggaactg tccaaccacc gatgtcacga ccagttactt gcatgtaaac atagcgtgtg
    22081 aaccctgagc agtcaaagcc acttggatct ttaccgcccc aaacatatgg agtaccaata
    22141 tatttgtaag cttctgctac gattgctgca ccattcacac ttccagaagg agctggagca
    22201 ggtgttacag gttttggttg ttcaggtgtt ggtgttggcg ttggagccgg agtactactt
    22261 cctgtgccgt ttcctgtatc aacactttga tctgttgatg gtgttgtagg cgcaggtgtt
    22321 gttgattctt ctgttgttga agattcaggc actgttgttg attcttctgt tgctgaagat
    22381 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcgctgttgt tgattcttct
    22441 gttgctgaag attcaggcgc tgttgattct tctgttgaag attcaggtgt tgttgattct
    22501 tctgttgctg aagattgtgt agctgatgat gattcttcag tcattgaaga ttgtgtagct
    22561 gatgattctt ctgttgctga gctttgtgca gtagatgaag cttgagtagc ttgtgcttca
    22621 gcctctgctt gttcgcgtgc ttctttttca gctttttctt gtgcagcttg ttgacgagct
    22681 tgttctgcta gacgttgttg ttcacgaata cgagcttgct ctgcttcagc ttctgctttt
    22741 tgacggttca agtcagcttt cttgtcttca gcagttgctt gttcagcagc taatgaagtt
    22801 ttcagtacgt tcaaatcagc ttgtttagat aaaagatcgc ctttttgaga ttccaaagca
    22861 gcttggtttt cagctaattc ttttagttta gcatcgtttt cagctttttt gtcttctaca
    22921 gcttttttat cttgtttttg ttgttccatc aagtcgttgt ttgcttttac catcgttgtc
    22981 attgcttgaa cgcgtccaat agcatctgct aatgaatcag cattcaatac agcatcgatg
    23041 tagtttgagc ttgtgttgct tacttgtgct tcgcgtgctt gtttttggat tgtatcttca
    23101 cgtttttcaa tacgttcttg taaatctgca atgtctttta ctaattgtgc agattcttga
    23161 cgcaatgtat cttgttttgc taataggtct tgtgcttgtg tgttgatttc agaaacttgg
    23221 ctttctaagg catcgatttg tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc
    23281 ttttgatctt gctgttgtat ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat
    23341 gctacggcag tcaaggtcat tgaacatacc attactgctg atattaaact ctttttcact
    23401 cttcattcct ccgactggct taatttaata aatatctaaa tatatttaag tctttcttaa
    23461 cgatataaaa attgtaccat agcagtgtgt caacgatata atagttatgt tacaaaaatg
    23521 tttcaaaaca acttttaaaa atgacaaaac tgttcgtttc agaaaatgat catgaaaaag
    23581 ccgcgttaag tctagcattt cttaagataa caacgattct ttttcgcttt cgacctaaaa
    23641 ataaaaaaag aaattattca tcactgaata atttcttaaa gggaaaaatg aataatacaa
    23701 atataatcat gttcaacagc agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat
    23761 ttactactgc taatttaaaa atcaactgga ccaccatcgt aaacaattca taacccgtga
    23821 caaagatgat catactgaaa aattcagtaa agatgttgac atggataacg tctttcatta
    23881 catacatcaa ccatacaatt aaagggagag ctactgcata gataccgata acgccaatat
    23941 agtaagcgtc atagatagcc ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa
    24001 acgccatact gcaacataat aatgccaata tcagaaagtg ggcatttgac atataggtgc
    24061 ctttcgacca ctcccctagc attcttgtta aatgaccatc tatcaacatc aaaaagaaca
    24121 aaacgattgg cagatagtac ttcattgttt ctttcttcaa catggactaa tcctccgcta
    24181 gccgttggac aatcgtcaca actgacacgt catacatttc tgcataaggt ttcacataaa
    24241 cttcccgatc cagcccataa ctatctggtt tcgttttaat aaccgtaccg atcggcaagt
    24301 tagctggaga attccctcca agaccggatg tctggacaac atccccttct ttgatatccg
    24361 tatcaccagt taattgggtc accactaagg catggagctt ttcatcatag tttttaagca
    24421 aaccaaacgc ttcgccatta gccgaagata cccgtactgg aaaatgattg gagctttcat
    24481 tagaggatga cagtaattcg attttagacg aagccgtatt gacctcgatc actcggccaa
    24541 tcaatccttt ttgcgacatg actgccatat ttgcttcgat accgtcttta gaacccttgt
    24601 ctacgatcag catgtcctgc caactgtcag gcgaacgagt aatgacattt gccgttactt
    24661 tttcgtaact agtcagcgtc tgattcaact caagttcttt tttcaacgct tcgatttctc
    24721 tctcgtaatt cttgttttgc tgtgaaacgt catcatagct atcgattttt tcttttagcc
    24781 gctcattttc ggcataagtt gaaaaaagat tatggacaga atctactcca tttcgtaccc
    24841 accgtactgg ggcagagatt gttttatcaa ccattgcaac actgtcatta acgatggatt
    24901 ggaagaaatt gggctttcct tcattcgctc gctgcgcagc ggtcacactt agtatcgtca
    24961 ccacgatgat aacaataacc aaggtaataa taatattttt attaggattg aacttcttca
    25021 caaagacacc tcgaattaat tagactcttg tgttcaattt tatcactaaa tgccgtgaaa
    25081 caaaaggtaa gttgctcctc ttaagctttt ttttagcaaa taatagattc tgtcattttt
    25141 agcctgaaag acaaattttt ttatttgttt atggatcaat ctttgctttg aataactgca
    25201 atcataccat ctgaaaaaga aaattctgcg gtatctgaaa gaaattcgtt acttgcataa
    25261 gatgtcggat attctacttc tttattttcc aatacatact tgctgccttt taatgtaaga
    25321 ttcgagacgg gagtcaagca gcaataagct aaatacttca tatctggtat ctgtcttact
    25381 atatgctctc caggcaaata ataagacaaa taattttgac aatctctgat aataagctga
    25441 tgggcaaagg gtttgaagcg aggttccata cctaaccaga gattggctaa aagatgatcc
    25501 aatcttccgc ccgtagctcc aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt
    25561 tttaagatac ctaactgtgt atctgtatcg tctttttctg caggggaacg ggtatactct
    25621 ttggcttttg caaatacttc cttctgctct tcgttcgaca atgaatcaaa atcacccact
    25681 gccagatcta ctgggtagcc tgcttgaagc aggtacagcg caccacggtc tatcccgaca
    25741 taggcatcgt atttggacag cagagactgc ggccagtttt gcggattacc tccagcagct
    25801 aataaaattt tcatttagtc taatgcctct tttaatcgtt cgatttgtcc gactggattt
    25861 tcggctccat agatatatga tcctgcaacg aagacatccg cccctgcatc tttacagatt
    25921 tttgctgttt ctggaacgat tccgccatct acttcgattg cataagtcca attgttctct
    25981 ctacgtagat cagcgagttc cgtaattttt tctactgttt cttcaataaa gctttgtccg
    26041 ccgaacccag gattgacagt catgactagt acttgatcag ccaaaggcaa aacatgtttg
    26101 atcatggaga ctggtgttcc tggattgata actactccag ctttaactcc taagcttttt
    26161 gtcatttgaa gtgcccgatg aatatgagga gttgcttcga cgtggacagt aatgatatct
    26221 gctccagctt ttgcaaatgc tggaatgtag ttttctggat caacgatcat cagatggacg
    26281 tctaacggta atttagtaac aggacggatt gcctgaacaa tatttggccc taatgtgata
    26341 tttgggacaa atcggccatc cattacatct acgtggatgt aatctgcgcc tcctttttcc
    26401 actaactcaa tgtctctttg taaattggca aaatctgcac tcaaaatgga tggtgctatc
    26461 ttcattcttg tttcctccta ttttcgttta ccttcttttt ttgcatacat tggttttctt
    26521 ttttcgattt cttgtaagaa ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct
    26581 gtttctactc tatgttttac ttcgcagcca ggttctttag catgcatgca ctctctaaat
    26641 ttgcaatgga cagaagcttc tacaaattca ggaaattgtc tcggcagttc tcctgcttca
    26701 attgtcaaaa agtcaatcga gctaaatcct ggtgtatctg ctactaaccc gccatagata
    26761 ggaatcagtt ccacatgacg tgttgtatgc cgtcctcttc caagtgcatc agaaatctct
    26821 cctgttgcta aattcagttc cggtgatatt tgattcagta gcgtcgattt tcctgctcca
    26881 gactgaccca taaagaccga tagccgttct gggaagtaac ggatcagttc tgtcgtatca
    26941 cccgtatgat tgggtacaat caccggatag cctattttag tataggtttg cttgatctct
    27001 tcgatttttt ctgggtcgtc tgacaagtcg gtctttgtca aaaaaataat cggttcgatc
    27061 gactcgtatt ccaaggtaac tagaaagcgg tcaagtagat tataagaaaa tgcaggctct
    27121 acgatacttg tgacaatgat tccaagatca acatttgtga ctggtgggcg aactaattga
    27181 ttttttctcg gcaagatttc cagaagatag ccgtctgttt gattttcact ctcaaagatc
    27241 acctgatctc cgacaagcgg cgtgattttc cgattccgga aatttcctct tcctcttgtt
    27301 tgataggtct ctccgtttgc gtatacatag taaaaaccgc tgattgcttt tctgatttgt
    27361 cctttgataa gtgccacctc cgtttttgtt tattttacca tacgaagagg aaagtaggtg
    27421 ttattccatg caaacttctc aaagtatatg gcttgaaaat tgatcaaaag agatagaaac
    27481 acaaaaaaga gaatgcaaca aatcaatgtc gcattccctt ctgatatatt ttattcagca
    27541 cttattttga actttctgag gtgctagctg atgaacttgt ggagctggaa gattcttctt
    27601 ttgaagagtt gcttgtgcta ctggagctac ttgagctgct agaactgtct gaagagtctt
    27661 tttcagaact agaagacgct ggatctggtc ctttagagta aattacgttc acaaccattc
    27721 ctttggtaat tgtcgttcct gcccctggta ctgtacgaat cactttatct ttatccaccg
    27781 tgtttgaata ttcggaagtc tcatgcccga tatattctgc accgacacta gctaaataac
    27841 tttgtgcttc gctttttgta tagccggaga tatcattcaa tttaggctct gttccttggc
    27901 ttacgacaaa attgatgtaa gtttcttctg ctacaacttc acccgaggct ggatcctgac
    27961 tgatgatcga acctgatggt acagtgtcgc tatagtcata agtagcacta atattattga
    28021 tattgaatcc ttgtgtaaca agccaattac gaacagtttc gtagttttct cctacatgac
    28081 tactcaaagt cactgtttct ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag
    28141 gatcgacttc tgtatcttct gatggagatt gcgaaatgat cattccgctt tctacctctg
    28201 aactgaattc ctcttctttt tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg
    28261 cttcggcatc ttcataactt ttaccactgt aatcatctaa tttgattttt ttcgtgccgc
    28321 tactaatata cagagtgact tcgcgttttt gcttgactgt cgttcccgct gccgggtctg
    28381 tcttcactac attaccttct tcgattttgt catctgcaat ttcttctgtt tttgttgcta
    28441 cttctaattt cgcttttgcg agtgtttctc tagcagaagc ttcagaaaga tcagaaacat
    28501 caggaacaac aacttctcct cgcccgccag aagcaaagaa tacagctgtt ccgattccta
    28561 aaacagcaag aatagctaat aggatcagcc accatttttt ctgtcctttc tttttaggat
    28621 caggcagaac ttcttcctcc tctggtaagg tttcgttttc tggcttgtct tttggcagag
    28681 gcatagattt gaatgaatca ggcattggtg catcttccgt aaggggtgtg ataacttttg
    28741 tttcattatc catcacatga ggctgccatt tttcttcgtt tgcacgagct ggtgataata
    28801 ctgtagaaag atcatcagac atttcctcgg ctgacttata acggtctgca ggttctttag
    28861 ccgttgcccg taaaatcacg ttttccagtg cttgtggcac atttggatca agtgctttta
    28921 tagatggaag atcatcttga aaatgtttta aagcaattgt tacagcagat tcaccatcaa
    28981 acggtacgct acccgtcaac atctcataaa ggatgatccc taaagcataa atatctgact
    29041 gcttcgttgc catacttcct ctggcctgct caggggacag ataatgaaca gatcctagca
    29101 tcgtattcgt ctgcgtgatc gatgtttcag ataaagcgat agcaatcccg aaatccgtga
    29161 tttttacaac accttcatta tcgatcagta cgttttgggg tttcaaatct cggtggatga
    29221 tttgatggtt atgagctaaa gaaatagcag aaaggatctg ctgcataata tttactgctg
    29281 tttcataagg aacaggataa tgtgtttgga tatatcgttt caagtccatt cctttgacgt
    29341 attccatcac cagatactgc atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt
    29401 ttggatgaac gagttctgtt gctgctaaag cttctctctg aaatcgtcga atcgcagtct
    29461 ggtcattttg aaagtcaaat cgtaagactt taactgctac atcacgatcc aagattaaat
    29521 cgtgcgccaa aaatacattt gccataccac cgctaccgat atttccagtg atttgataac
    29581 ggccatttaa ttttttgccc aactcgatca tacactgtcc tccttatatt cgataagaag
    29641 aacggtgata ttatccgctc cgcctgcttc attggcacga tcaatcagct cagttacttt
    29701 atgagacaat gggccttctt gattgatgat cgttcctatt tcttcttcag acagcatgtt
    29761 cgtcaagcca tctgaacata acagcagtcg atcttttagt tgccaaagat gagtagaaac
    29821 atctacttcg actgttccag gcatgccgac agaacgtgtt aaaatatttt tccttggatg
    29881 gttcactgcc atttcttcgc tgatttctcc tgatttgact agttcattga ctaaagaatg
    29941 atcctccgtc aattgcatga ttttatcttc acgaatcaaa taagctctgc tatccccaac
    30001 attggcaatc gtgaaccagt catctgacag agcggccgct acgattgttg ttcccatacc
    30061 gttatattcc ggctgttctt gtccacgctg ataaatcagc atattttctt cttgaatcga
    30121 ttgaatgaac cattgggcga ttttttcatc gtcaacagct tcttgttttt cccaagcttc
    30181 gcctagattc gttaccgcca tctgactggc aatgtctccg gcacgatgac cacccatccc
    30241 gtctgctaat acagcaagct tgagacctga acggctggta aatacactgg catagtcttg
    30301 atttgtgtta cgtcgtcttc ctacatctga ttgatattca atctgcattt tttcacctca
    30361 ttactttttg cgcaaacaac aaatgaaaaa tccatctgtg taaaactgat gcggatacaa
    30421 agtcaacatt ttctcttcga ttgatgattg tagcatagga ttggtcaaaa catcaatcct
    30481 ctcaaaatca gggtgtcttt ccaagaaagc agaaacaacg tcttggtttt cttcttttaa
    30541 gatcgtacaa gtgctataag tcagaatacc ggaagacttt aaagttggtg cgcagctttc
    30601 taaaatttcc aattggattt ttggtaaatt cgctaattca tccggctgtt ttttataacg
    30661 aatatctggt tttcgccgaa gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg
    30721 atcaaactgc tctgcttcga actgtttact gacttctcta gcatccatct tttgagcgta
    30781 gacagcagaa gagacaccta gacgtgctgc attatcttca atgagtttga ctttgtgttc
    30841 gtgtacatct aaagcgacca cttctccacc gcatgacgga tctaaaaaag aagcaatatg
    30901 cgtcgtctta cctccgggtg ctgcacaggc atctaagaca tgatgttcag gctcgatttg
    30961 catagacggc gctacaagca tcgaactttc atcttggatc gtcatgacgc catcgtggaa
    31021 caatgagcta gaagctaaat gccctttttt cgctactata ccgtatggac tgacttggct
    31081 tttttcagct gtgatctctt cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg
    31141 gcgtgtatct actcgggcac tagcatggct aggctgatat agcgataaac cgagcttttc
    31201 agtttcttcg tatccgattt gatccaccag tcgtttcgtc atccatagag gcaggctgat
    31261 tttgacagaa agtctttcga taggatcagc aatgccttgc agatctggtg ctccttgacg
    31321 ctgataattc ctcaagacac catttacaaa tttccctgtc ccaggatttc cttttacttt
    31381 tgcgatttcg accgcctcgt ttaaaatagc atgtgcaggg actttatcta aaaattctaa
    31441 ttggtataca gaaagataaa gaagcatctt gacccagtca tccacttttt ttgctttagc
    31501 gatcaatggt gcaacgtaaa attccaatag tcgctgatgg ctaatcgtac catagatcaa
    31561 ttctgtaaat aaacccacat ctttttgatt tagctcgctt tgtttgatca tctcattcaa
    31621 caaaagattc gagtaggcgc cacccttgtt cactcgctct aatgtcagta atgccatata
    31681 tcgtactgat tttttcattt ttttagggat ttttttcatt atttcacctg ctgaccaatc
    31741 tgaacttgct gaccgcttcc gttaaggaaa tcatgtacgg cctgttttcc tttaccagct
    31801 ggctgtaatt cattgatggc taagacggtc tgtttaccgc aagcaatcca tagatttttt
    31861 ttgtctttcc ggatgatcgt accaggtgct ttgtctgtag tttctgccaa tacttcaacc
    31921 gataataatt tccagcgtat gccctcatag gtcgtgaatg caattggcca aggacgcatt
    31981 ccgcgtactt ggttgtcaat ttcttctgca gttttatgcc aatcgattgc ttcttgttcc
    32041 cgtgtgatgt ttggcgaaaa agttgcttct gactcgtctt gaggtactgg tttttgtcca
    32101 tccaaaatat tgggcaatgt ttctagcaat agctttcttc ctaaaaggct aagcttttca
    32161 aacatcgtcc ctacatcatc ttgtttagtg attggtatgc tttcttgcgc atagattccg
    32221 cctgcatcca tttttttgat catttccatg atcgttacac cagtttcttt ctccccattc
    32281 atgatggcat aatgaacagg cgcacctccc cgatatttag gaagtaaaga agcatggaca
    32341 ttgattgccc ctaattttgg tacttgcaat aacttttcag gcaagaattg gccaaatgcc
    32401 gcagtgacga tcacatcagg caccaattca atgatttctt ccatttctgg cgaaccggag
    32461 attttctctg gctgcagcac acggataccg tgcttcagag ccgctttttt taccggtgtc
    32521 ggcgtaatta ctcgtttccg cccaactgga cggtcgggct gtgttaccac tgcctggatc
    32581 tcgtaacctg attctatcag cccttcaaga atcggcacag aaaaagcagg tgtgcccata
    32641 aatactagct tagtcatcaa gatgttcctc catatattct tcaagttctt cttccgggat
    32701 ctgctgtatc attttctcaa tgaacaagat accgtctaag tgatcgattt catgctggaa
    32761 ggcacgggct aaatagccaa aagccgtcac ttctatctct tctccgtctc gatcataata
    32821 acgcacggtc acttcatctg ctcgcttgac cgttccatag acatgcggaa tactgagaca
    32881 accttctacg tcaaggcttt caccttttgc ttcgatgatt tctgggttaa tcagttcaaa
    32941 tttctcgcct tcatctactt cgatcacagc aattctcttg ttttgtccta cttgaggagc
    33001 agcgatccct attccgtcat tcgcaatcat tgtctcatat aaattgtcta ataaagcgat
    33061 tgtctcgtcc gtgattacat cgattggctg agcagttctt tttaatttat cattagggtg
    33121 gatcaatata ggatagcgca taatttggcc ctttcttaaa taaagtttaa tggttcgttg
    33181 tcaattgcca caaaaagacc ttgtcgctgt tctttctggc ttccattcaa aatttcatcc
    33241 aaaacatgag gaagattcgg ttcatgttta tatttgatga ttagttgata ataatatcgg
    33301 tttttcactc tcaaaatcat gctgggcgtt ggccctaata gcaagctttg agggcttaac
    33361 acttctttta gctgattggc aatctgaaag attttctttg ccgctacttg ttcttcagga
    33421 tggctggcgg ttattttcac agtaaagtaa taaggaggat agcctccacg atgccgtaca
    33481 tgcatttcct gctgataaaa ctgctcataa ttttgttttt tagccaattc tatggcgtaa
    33541 tgttgaggat tgaatgtttg gatcacgact tcgcctgctt tttccgctcg ccctgctcgt
    33601 cctgaaactt gggtaagcaa ttggaatgta tgctcactag aacgaaaatc cggtaaattc
    33661 agggaggtat cagcattcaa caccccaact aatgtcactt ctggaaagtc caaaccttta
    33721 gcaatcattt gtgtccctaa taatatatct gcttcttttg caccgaattt ttgtaaaatc
    33781 tgttcgtgtg ccccttttct tcgagtggta tctacatcca tacgcaaaat cctagcttgc
    33841 ggataaagtt ctcggagttc ctcttctact ttttgagtac ctgttccata gtagcggatt
    33901 ttattgccgc cacaattagg acagcgattg ggaataggtt cttcatgtcc gcaataatgg
    33961 cagcgcattg aacgtgtatc catatgcagt gtaagagaga tatcgcaatt aggacatgga
    34021 agaacaaatc cacagtccct acacatcaca aaagacgaat atcctcgacg attgagcagt
    34081 aggacagttt gttctttttt gtctaatcga ttttgtattt tttcctgcaa attagcagaa
    34141 aaagtagagg tccgatgatt ctgaaactct tcacgcatat ctacgatctc aatagctgga
    34201 agctgtgcag ctgctttggc tcggtggttt aactgcaata actgataaac gcctttttga
    34261 gctcgtgctc ttgattctaa agagggcgtc gcgcttccta gaactattgg gcaatgatga
    34321 tatttactgc gccaaattgc tagatctctc gcatgataac gcggtgtctc atcttgtttg
    34381 taacttgatt catgttcttc atcgataatg atcagcccga tatttttcag cggggcaaaa
    34441 atagcagatc gtgcgcctac tactacttgc gcttcttccc gctcaatctt gcgccattca
    34501 tcatattttt caccttggga aagtccgcta tgtaagaccg caactgattc tccgaagcgt
    34561 cctttgaatc gctcgaccat ttgcggagtc aatgcgattt caggcactaa cataatagcc
    34621 gttttatttt ctgacaaaac atcagcgatt gcctgaagat atacttctgt tttcccgctg
    34681 ccagtgattc cctccagcaa aaagacctga tctttttgct gctgacctgc tgtgatgatt
    34741 tgttcgacag catttttttg ttctgcattc agttccaatg ccgtcgtttg gtcaaatact
    34801 cggtctttat aagggtcgcg ataacgttct gattctataa actccagcca gcccttttct
    34861 tttccttgat tcaagacagc agtactgatt cctttatttt tgaaataagc aattggttct
    34921 tcttggctca gttcagataa acacaaaaga agttcttttt gtttcttggc attttgccgt
    34981 aattttgccc attcttcttc gatttgcttt tcagttaaca aagaacggac caaacgaatc
    35041 gtttttactt tatttcgtgt atggacttca tatttgatat ctactaattg ctcttggcgc
    35101 cagcgaatca attgagaaag gctgccttct tcttctgctt ccttccagga aatcacttct
    35161 cgctgatcaa acaatacctg aacttctggt gtgtctgcca aaggatagat caatttatca
    35221 tattctgctt tcatcacact cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa
    35281 gtaatttttt tcatataatc agctaatgaa agtaattctt cattgaccac cggagcaagg
    35341 tctagcaaac gaataactgc cttcaaagat ggattagctg attcttctga tttttggata
    35401 gccataacaa atccttggac atgacgattg ccattaccaa aagggacttc tactcgcatc
    35461 ccgacttgca aagctgtttc catttcagag ggaaccaaat aagtgaatgg ctgatcggtc
    35521 tgcatagtag gtacgtccac aatgacttca gctgttaatg tcatggttcg tttcctcctt
    35581 tttttgtctt ttcttatcaa gcgacaaaaa gttccttgcc tattttacta gagatcgatg
    35641 gatttgtctt atcttctgcc aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag
    35701 aactgtgtca aaaagttcag acacagcctt ttctaccaga caataagtgg cgaatgtttg
    35761 aaaaggaaac agctgggttt gcttttcttt ttagatgttc gctctatttt tctttattac
    35821 attttttgct cttcacggat acgtgattcc aattcgtgtt gttcacgctc tttttgtgct
    35881 tgacgttcct cttcttccat cttcaaacgt tcacgtttta attcaggatg tggatcattg
    35941 actacatttc ctgcatcgat ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa
    36001 gaatctagag taggctgtgc acttgcatcc aattcatgcg cgcgtttact tgctaaaatc
    36061 actagagaat attttgaatt tacacgatct aatagtgagt caattgaagg ttttaacatc
    36121 ataagactac atctccttta acattttaat atatttaccg attacgcgat ctactcgaaa
    36181 atgttcactg gcaataatgt ttttgattcg ttcaactgct agcggcactt catcatttac
    36241 aacagcatag tcgtaaagag ccatcatttc gatttcttct tttgcaactt tcattcgttt
    36301 ttcgattact tcatctgcat ctgttcctcg gcctacgatc cgtgatttta attccgctaa
    36361 atctggcgga gtcaaaaaga tgaatacacc atcgggcact ttttctttga cttgttttgc
    36421 tccttggact tcaatctcca agaaaacatc ttttccttca tccaatgtct tgttgacata
    36481 tgacaaagga gttccataat aattcccgac atattctgcg tattccagca tctctccagc
    36541 ttcgatcatt gattcaaact cttctttgct tcggaagaaa taatcaacgc cttcgacctc
    36601 cccttcacgc attttacggg tagtcattga gatcgaatac tgaaaatcat tatcctcact
    36661 ctcaaaaatt gcttttcgta ctgtgccttt tcctacaccg gatggaccag acaacacgat
    36721 taataatcca cgctctgaca tgacgacgtc ctttcaacta gtctttttgt acttatcgtt
    36781 tattttgcac tttttttctg caactttcaa ggttatcttt aattatagct agaaattggt
    36841 aaaaaagcta ccctgtacca agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa
    36901 cagccaaaca taaacagctt ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc
    36961 aagcttttga acgccgtgta taagaggtcg tgaagaagcc gattagtttc gagtatgaag
    37021 aaaaattttg tgaaaatagt ttctcacatt tttgcataaa tttggcttaa taccgagaaa
    37081 atggtttttg aacatcactt attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca
    37141 acctttaaat gtattcctag agcaaagaag ctaagcgaag aaatccaatt ctgtttattt
    37201 attgtatttc tttgttcagc atccttgcta aaagcccata ttggacaaag tattcactac
    37261 acccatgatc tcatcttttc gagaacgtgc tttttctgtc ggatcttcta cctcttctgt
    37321 gtcaattcga acaataaatt tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat
    37381 aaacagttcg ttctcattat agtctgcaca ggcatctttc catacgtcaa agccgttttt
    37441 ttcagaaggg atatcccgtt taaccacagt ttttccactt aattcgtgga acgttacgtc
    37501 ataatatttc attatctcta cctctttcgt cattcaatat tttgtacttg ttctctgatt
    37561 ttttctaaga tcgtcttaga ctggacgact tgatttttaa tttcgattgc atttgatttg
    37621 gaaccgatcg tgttgatttc ccgattcatt tcttggatca ggaaatctaa ttcccgacct
    37681 acaggacatt gtgcttcgat aagttcatct agtttttgta catggatcgc cagacgatcc
    37741 agttcctcgt gaatatctcc gcgttccaac aagatggcta gctccgtcaa caaccgttgc
    37801 tcatcgactt tcgctccaag aaattcctcc agcttttttt gataccttat ttgaaattcc
    37861 ttttcataga tttctacaaa actatcgagt ttttttagta cttctttgaa ttcttcagta
    37921 ttctttttca acactaaagc taaagcttga ccttcttttt ctcgactcgc ctcaatagaa
    37981 tcaagtgcgc ttttcaatgt atctagagct aactgtgcca attcttccat gctctcttcc
    38041 ggtttttctt ctaccgttac gaagttttcg tccagcacga agcgttccgc catccgacta
    38101 attgacactt gattttgact accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata
    38161 agtgaatcaa tcaattccca gttgatgacg atctgttttt cgtttttgcc aatataagct
    38221 agattcacaa atacttcgat tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa
    38281 tcgttttcaa caaagttcag gattttagga cttcgtattt gaacatctag aaaacgctgg
    38341 ttgacacttt ttatttcaat atctaactga tacgcttttg tttcgcggat ggctttgcca
    38401 aaaccagtca tacttttcat tcgacagggt ccttcctcat tacatatttt ctattgcttt
    38461 ttgcagttgt tcaaactctt cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc
    38521 tggcgcccaa tctcgaagat cgaattttgg cgggcgacca ttccagctga ctaggttcag
    38581 ttctttacgc caccccttgt tgttttctga caatatagcg atttcttcta cgatttcata
    38641 tgaaaattct tgtgccatgg ttgttcctcc ttgagataat ataaatatag gatcagtaat
    38701 gtgtcaactg gttgcttaag caattcatgc tgcaaacgat ccttgcgttt tccttgtagc
    38761 agataatcaa aataaacagt tttcgtgcgc tcattttgta ttttttgctg gtattttcga
    38821 taccttcgcc attcttcagt acttaattga ccaatttgtg ccaataaatc atccggcata
    38881 ctttttatat cttgttggca gatcatttga atcatcatgt ctacttgata gatttcattg
    38941 ggcagtaaaa aatgtttttt tgctaaaagt tctagcatcg ccaatccgca tgtctctggt
    39001 acgaccctgt tcttatataa attacgcagt ttttgccaaa attttatgct tttgaaaaaa
    39061 gataattcta actgaatttc ttttgttaag taagacaaaa atcctcgcca gtatgttctt
    39121 gcaggtttaa cagaatgaaa tgtataccag ttcccatagt aatagcctaa tcgttttttc
    39181 atttccagat agcctaattg taaatttaat tggttccttt ggctatcaaa aagcagaaag
    39241 ctgcctagtg tccacaatgt ttgacatttc caatggataa aaatgtctgg catacgaatt
    39301 tttttcgctg ggcctggccc ttgcacatct acgacaaatg cctctgttgc tcctttgtta
    39361 atcgcaatat caataggtat tttgttgcga tacccaccgt ctgcatattt attttttccg
    39421 atctttcgat aagccatagc gggataaaat gaagcagagg cgagtatcca atctggtatt
    39481 tcttctgttt ttgtctgttg gatatcagtc actacttccg ctagttctgg cagtttagta
    39541 gacaccgtat ataaacgtat tttgggatta tgtttgagta aggacaaatc caaattgtct
    39601 ttgaccatct tttccaatgg agcagaagaa accccgcctt caattagtgc tgttttcgtc
    39661 atttggcgtc tttctcgata gaagcgttca cgaaggtctt caactgcagc catttctggt
    39721 aacgcaagca cttgtcttgt cgacagcttt ttccataaat tcacagcttt tttcatatct
    39781 ccttgtaaaa tcaatgcgcc gttcaacgca cctaccgagg tacctgtgat aatctcaaag
    39841 ttgatatcat gttccttcag cgcctgccac acaccaatct gataagcacc gtgcgctcct
    39901 cctccaccta aaacaagtgc tgtatgatag accagctttt tatttaattg tgtggttcct
    39961 tgatagccgt ttttatgaaa aatacgcaac cattcttctg atagaggaga ttgaaataaa
    40021 aaacaacagt tttctttaat aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt
    40081 ttccattcaa aagtttcacc ttcaatcaac agattattaa aaataacatc tcctctactt
    40141 ttagcaatag taaaatagac ggtatatttt ttcgatactg ctttaaaagc acattgcttt
    40201 tttgcagaac gccaaaaagc gtctctactt tcttgatgac tttgaaaaaa tggaaggggt
    40261 tgttttgctt gctggatagg cgaatacagc gacattttct gtgaaaagta aacttttttt
    40321 atctccatcg cgctctcctt tttcttcaag tataccagta cgtcataaaa aggtcatgag
    40381 tctcgtattc gactttgtag attccataag aaaacaattc ataaaacctc ctttaaataa
    40441 aaaaatacaa aaatcacaaa aattaattga aaatgagagt gttttcaatg aaaacgtgat
    40501 tttgtaatgg aattttaaaa taaaagaaac aagctttttt aatgcaaatg ttgtaaaata
    40561 aaagagatta agaggaaata agaggaggaa catgatgact gagtcagttt atgtacatat
    40621 tgataccaca agtaatgctg ttttaacaaa agggctgact gctactgact ttgcaaacag
    40681 tatcgtgcat tttcctcaaa acttgctctt gcttgatcca tctgcttctg ctggagaata
    40741 tgaatcccat acagggctga aagtaatccg tggtacagaa aatattcagc gtttcttttc
    40801 ctcttctcgt aacaggcgtg gattcgatga attgaagtgg atcgacttta ctgatttaac
    40861 gatgctgaaa gaattgacac ctttagaaat ttcagaatta ttatattttg gtcatatgaa
    40921 aacacatctt cattcgccgt ttttttataa actacagaat aattttgtat acttcgatct
    40981 taatgatcag ctgaatcgga tttattatcg ctatttagat gaattttata ggatttttgc
    41041 tagtaaatta agttcgatct tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa
    41101 agaaacacct gttgaaaaaa tcagtgtgga attattgaaa gaaatgcgta atttgatgca
    41161 ggaagggatc attttttctt ttgatcaagt tggtttgatc gatggtaaat atcgtatccc
    41221 aatctatgtg attgaagatt atatttggaa attaaaaggc acccggtatc gagaagagga
    41281 aatcatcgct actttaatct actctgtcac cgatcgacac tggcaattgg tagaagatgc
    41341 cgatctttct tatctgccat tgaagtagat ctatttctta tcaaaaaata aaaaggaaac
    41401 aagaaactag gacatgattc tgtctcaagt ttcttgcttc ttttttattt acagctcctg
    41461 tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg atccctaata aaacgatgat
    41521 cgttacaata gctgtactca acccgctggc accattcatt acgaaagaaa agagccaagg
    41581 attcatcccc catagtgcat acgctcccca gaaaaccact cctgcaataa aatgccaaaa
    41641 atatctggaa agtgcgccaa tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt
    41701 attatcgtct acatagcctt tttggacatt tgaagccatg agccctgctg cgcctgcaaa
    41761 agtataggca atcgggtact caatcaacac ttgaacgaca cttaaataat aaacttgtcc
    41821 caacggaaaa tgtaggatgc cccaaatgaa acctgccagc atccctgcct ttgtccctct
    41881 tcttaacgca aaaagagtca atggaatctg ccctaatgaa atagaaaaac tgctgccgat
    41941 ctggatcgga atcaacgaca acaccatcgc taacgctgca acaatcgttc cttctaccca
    42001 aactctattt tttcccataa aaaaacttcc tcctttgaat aaaaaagtca caaaggagga
    42061 agcagctttc gaaaatagtc aaacagctgt ttattcacaa ttcctacgct cgcataaccg
    42121 atacaggtac gaagggttta gaaatagatt caatctcagc ccaattggac tcccctttgt
    42181 gagtttattt attatttatt ttttgtttca aacaatggac taactggttt gttttcatgg
    42241 atacgtttga ttgcatctcc cattagtccg ccaacactta cttcatcgat tttgtcgatt
    42301 ttacgatctt ctggaagata gatcgagtct gtaacaacta gacgctcgat agctgaatct
    42361 tctattcttt gtaaagcagg gccggataat actggatgtg tacatgaagc atacacacta
    42421 gttgcaccag cttctttcaa agcattggca gccaatgtga tcgtacctgc tgtatcgatc
    42481 atatcatcga tcagtacaca agttttgcct ttgacttgtc caatgatatt cattacttct
    42541 gcaacatttg cttttggacg gcgtttgtct atgatcgcaa tcggagattt caaaaattcc
    42601 gctaatttac gtgcccgtgt gacaccacca tggtctggtg aaacaacgac aacatcatcg
    42661 cctttgattc ctttttctaa gaaataattg gcaataagtg gcgcacccat caaatgatcg
    42721 actggaatat caaagaaacc ttggatttgg actgcatgaa ggtccaaagt cagcattctt
    42781 gttgcaccag ctttttgaat catgtttgct actaatttcg ctgtgattgg ttcccgtgca
    42841 cgtgctttac ggtcttgacg cgcatagcca taataaggca tgactacgtt gattgttttt
    42901 gcacttgctc gtttcagtgc gtcaatcatg atcagcaact ccatcaagtt atcattgact
    42961 gggctgctcg ttgattgaat aacatagaca tgcgatccac gaatactttc ttcaatgttt
    43021 acttgaattt ctccatcact aaattgagta acagatgatt ttcctaactc gacgccgact
    43081 gctgctgcaa ttttctctgc taatgggcga ttggaattta acgcaaaaat ttttaatctt
    43141 gggtcaaagt aatgttttga catggggacc tccactttct ttttcacaac tctagaattc
    43201 tacctaataa atagtagtca tattttttaa ataaatcaag tgattttgca aaagtcttag
    43261 tttagataag ggagtttttt tgcatatcct tctttattga cttgtcttgc tctcgcaatt
    43321 gccagcgcat attctggaat attgtctgta attgttgacc cggcagcaat cgaactgttt
    43381 ttagctacct cgacaggtcc gatgatattc gtgctagaac caataaagct gtggtcgccg
    43441 acagtcgtat gatgtttgtt ctttccatca tagttgacga agacaacacc acatccgaca
    43501 ttgatttctt ctcccagcgt agcatcacca acataagtca agtgaccgac tttagttcct
    43561 ttgccgattt gagcattttt cacttccaca aagtttccga tatggacgtt ttcgccaatt
    43621 tcagcttttg gtcgtaaatg tgcataaggt cccacatctg catgtttctt gacatggctg
    43681 ctttcaatga ctgagttttc aatgacgacg tgatcctcaa tcctactgtc tacgattttt
    43741 gaatgtgacc cgatgacaca atcagaacca atgactgtat ttccttggat ttgtacacct
    43801 gcttcgatca atgtgtctgg accgatttct acgcctgcat cgatgtatgt cgttgctgaa
    43861 tcgacaaagc ttacgccatt gaccatatgc atctggttaa ttcgctttct catgatctca
    43921 tttgctttag ctaacgcgat ccgatcattg actcccattg attcttcaaa atcatccgtt
    43981 tgataagcag caactgtatg gccttcttct tttaagattt cgatgatatc tgttagatag
    44041 tattcacctt gagcattgtt tgttccaact ttgcttaacg catcgaacaa agcttcgttg
    44101 tcaaaacagt aagttcctgt attgatttct tgtacaagag cttcttctgg tgttgcatct
    44161 ttttgttcca cgattttttc tacgatccca atatggtcac ggatgattcg tccatatcct
    44221 gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg cattttttcc ttggtgatat
    44281 tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg tatcgccact gataactaac
    44341 gttgttcctt tttttccttc caagaaagaa gcagcttgca aaacagcatg tcctgttccc
    44401 aattgttctg cttgtaacgc atatttactg cgttctccta gttgtgcttt aacttgttct
    44461 gctccgtgtc caacgatcgt aatcacttca tctggtttcg tttcactgac ccgattaatg
    44521 atatgttcta ccataggttt accagaaacg ggatgtaaaa ctttatataa ttttgacttc
    44581 atgcgggtac ctttccctgc cgccaaaata attgcataac gtgcgtccaa ctgcgtcact
    44641 cctaaatata gtttgctgat ttcagtttat cccagtatac ccattttttc aacaaaacaa
    44701 gtgattttct tttatcccag cgttttctgg ataaaaaaat agatagacca taacgggcct
    44761 atctatttgg taaccggtgc tctcctgcca actcctcggt cacaagtcac actactcata
    44821 aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt
    44881 acaacctctt cattaaacgt ttttcaatca gctgaccttc ggtattagct caataaacgg
    44941 caaaatatga ggagcaattt ttccgtttat tgagctaata ctcaggacag gacgctgatt
    45001 tcacaacctc tagataaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat
    45061 gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac tactcgaaac taagcggctt
    45121 tttcacaacc tcttattctg aaaaataatt tcctggcaca accgtaatat ttttcgtttg
    45181 agtatctaca tctttgacat aaagcagtga cgtataatca tcgatggcgc gatgaccgtt
    45241 gaattttgat tcggcaaata cagtgatgcc aacaagttct gattcgaatt cttcaatcaa
    45301 gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa tcatccacta caaggacacg
    45361 tgaaccacgt ttcaaacttc tcttagacag ttccatcttt tcaattcttt cagaagatcc
    45421 agacacatag ttgacactta ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat
    45481 aacgaatggc gcattcagat aataggacac agcttgggca ataggtacgc cttttgtggc
    45541 tacagtcatt acagcatcga ttttttcacc aaggtattta gaagcaatga ttcttccaac
    45601 ttgacgcagc agttcaggtt ctcctaacaa atcagagaga taaacatatc ctcctggaag
    45661 cagacggtct tgttctgata gacgttctgc tagagattca atatattttt tcgcctcttc
    45721 atatgaaatt tcagggatga acaatacacc acctgcagca cccgggattg tttccaaggt
    45781 tccataccct cgttctttaa atgttttctt gatgattccc aaatcttcac tgatagaaga
    45841 tttagcagat tcataacgtt cggcaaagct tgttaaggaa atcaattcat gcgggtgatt
    45901 caataaatac tgtgtcatgt caactagacg ttcactgcga cgtactttca cctattccaa
    45961 ctccttttaa gaaattttat cgttttacat tatataagtt tttcttcaaa aattcgagca
    46021 ttttatgaaa aaataagaaa atagttcggt atttattaaa ataaaaagaa gcctataaaa
    46081 aatttttcgt ttttataagg cttcttttct ttataattta gttatttttt cttctgaagg
    46141 caaccaatat tcgtttgatg atatttacaa tcaggaacaa agcaataaag actaatgtga
    46201 ttgttgctcc tggaggtgta tctagataaa acgagctagt tagtcctgac agcatcccta
    46261 gaaatcctac acaaacactg atagcaatca cgacattgaa gcttttgcct aatcgcatac
    46321 cgattgctgc gggaagaacc atgattgcgg atatcaaaag tgcaccggca atcgggatca
    46381 tcacagcaat agccacacca gtaatcacat tgaacatcat cgacatcaaa tgaacgggta
    46441 gcccatccac gtgggcggta tcttcatcaa aagtcagaac atacatcggc cgtttgaata
    46501 aaaagaacaa tataccgatg gcaacgaata agattcctaa aaagatgact tgctcccatg
    46561 taatggtcac gatcgaacca aacagatagg attggatact tgttgctgaa ttccctccgc
    46621 tcaaattcat caatactaac gctagcgcca aaccaccagc cattaaaatg gcaatggaga
    46681 tttctgaata ggttcggtag atcgttcgca gatactccaa tatcacagct gctaatacaa
    46741 cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa gaatcctaac gctacccctg
    46801 ctaaagagac atgagaaagc gtatcagcca tcagcgattg tcttctgatc actaaaaaca
    46861 cacctagcat cggggcgatt ccggcaatga agatagcggc aagaaacgct cttctcatga
    46921 attcatatga aagcaacgcc attgagaatc ctcctttctc accagtcgga tctgtctgtc
    46981 cgcatactgt ttgatatctt catgatcatg ggtgatcatt agaactgatt tcccatggac
    47041 atgcgcacta tgtcggagaa gacgataaaa ttcatttctg gattcttcat ccatacctgt
    47101 tgttggttca tcaagaacaa ataagtcagg gtcagtagca aaaatacgcg ctaaactgat
    47161 tcgctgcttt tgtccgccag acaattcacc tattcgccga tttcgcatat cccacatccc
    47221 tacagcttct aaagcacgct gtacatgttg atgatctttt tcagagagac gcttgaacca
    47281 gcggcctctt ggatatcttc ctgaacggac taattcgatc accgtactag gaaaacctgc
    47341 attgaaagat gcaacttgtt gaggaatata accgatactt aatttttttc cttcttgatt
    47401 tttctcagca atctttatca ttccttttga aggtttcagt aatcctaacg atgctttcac
    47461 caaggttgac ttggctgctc cattttctcc agttaaaatg acaaattcac ccgcatctac
    47521 atgataagag acatcttcta gtacaggttc atcatcatag taaaaggtca aatcagatat
    47581 ttcgatataa cgcaccttac aacctccatt ctaaaactta attgatactt tcttttaaag
    47641 ctttcagatt tttttccatg acagaaatat aattttcgcc tgctttgatt tgttcattag
    47701 tcaagctttc taaaggattc aacacttcta gcttcactcc tgtttcattc gacaatgtct
    47761 cagctacctt cgaagaggca ttttcttcaa aataaatcac tttgatgttg tttttcttca
    47821 caaattcttt tagctcagct aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg
    47881 aaatcgctac ttgttttaag tcgtattgat tcgctaaata agcaaaagca gcatgctgag
    47941 tgacaaatgt gcggtttgtt gcatctttta gctcatcgga gtatttttga tccagtgctt
    48001 caagcttttt gatataagca tcggcattct tcgtaaaagt ttccttttta tctggatatt
    48061 tttcgcctaa ttcttcagca atcgttctga cttcttttat agctaatacc ggatcgagcc
    48121 aaacatgtgg atcgtattca tgtgaatgac catgcccttc ttctgattct tcatgttcgt
    48181 ctgcttcttg cgattctaaa cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt
    48241 tgctatccac tgaatccttt aacgaatcca caaaaaattc catgtctgaa ctattataca
    48301 cgaaaacatc tgcatcggaa atttctgctc tttcttttgc acttggttcg aaatcatgcg
    48361 gctccgttcc agcagggatc aaaagtttca cgtttccttc atcccctacg atctcttttg
    48421 taaaatcata catcggataa aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt
    48481 ccttgttcgt atttccacat gctgcaaaca gtaaagcacc tatcattacc gtagctgtca
    48541 aaagatattt tttcatttat atgctccttt caatgaacaa atcgtaattt tacgatttat
    48601 taacgtgaac taatgtatca aaataaaaaa acacagtcaa tagaaatcca tcaatttctg
    48661 atttaagcat gtatattctt gattaaatcg taaaatggat gagttgctgc tcatatctag
    48721 ccatttcact acaataaaaa actgaagaat accattttag gattcctcag tttttcatca
    48781 cctattttac ttcttatatt ttattgcagg gttcgtacta aataaacttc ctcacaaaaa
    48841 ccttttaacc cattatatac tctctgcgct cttgaataat gttgacacaa ggcaaaaacg
    48901 gttggtccgc ttccactcat caatgcagca tctgctccgt acttgatcat acgctctttg
    48961 atttgatgga tgactggatg ccgctttccc gttatatctt ctaaactgtt tcccattttt
    49021 ttgatcatct gctgataatc ttgctctcgg atggcttcag caagtccgtg gatgtcttga
    49081 tgttggatgg cttgcgtatc tacttctcta aacactgtac gtgtagagac actcattctt
    49141 ggtttgacca acacaaccca gcactgtggc atagaaggta atacttggat ttcttcccct
    49201 ttgccaccga caaatgccgt acttccgtag acacagtaag gaacatctgt accgacttcc
    49261 aaaccgattt ctgccagttc ttctaacgaa cagcccagat tccataattg gttgatccct
    49321 cttagagcag ctgcacagtc tgtacttcct ccgcctaatc cagctgctac tggaatattc
    49381 ttcttaacaa agatcttgac accggttttg atattgtatt tattttttag caataaagca
    49441 gcttgataaa cattgttccg ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg
    49501 attttgtctt ctgttatttc ttcaaaaaat agatgatctg ccaagtctac gctcgacatc
    49561 accatttcca actcatgata cccatcttgc cgtctatata atacatccag tcctaaattt
    49621 atcttggctg gcgctttttc aatcaattcc atcctctcac ccattcgaaa agtctaagtc
    49681 gcaagtattc tatcataggg aaaaataaaa gtatagctta tgtctgccta gtggttgatt
    49741 ttgtcatcgt ttcaacagct ttcacagaat tttctcttca taatccaaac aagttctagt
    49801 gattcttata attctgtgag cacttcttct gccaaactcg gaacatttcc tttttctttt
    49861 cctatcagac tgagtagctg catggtagca aatccgaaat tacttccttt cctataagca
    49921 aaataacgtc cttcccaatg atcgacatat tttaatttct tttcataagc agactggaag
    49981 gaatagaaaa aattaccata attatatacg atatgcatga ctttttcttg aaagaaagaa
    50041 aaatctgttt ctccaacatt agctaatgga gctaagccta gattggcttc cgagtagccc
    50101 attttctcgt atacaataaa cagattggct aacagatagt cagctaattc ctcagattct
    50161 ttaggtaaga cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg
    50221 atgaagccaa cgactttttg atctttacgg acaataccga caccgctaga taatacatat
    50281 gatttatcaa atcgtcccac agagaagtat ttttctcgtg caccttgaag ccatttttgt
    50341 gaaacttcat ttacagcttg atgtaattct tccggcagtt gatcgtacca agtaaaatgg
    50401 tatccttctt tcatcaaacg ttgatattca agttgctgac tcagccgaga caagtcttct
    50461 gttgctagat caacaatccc tgcttcacct actttcgtga agtgaaaacc caattcatga
    50521 agcatcacta cgtagctttc tgatatctta taaaacgcaa gctgatagcc taaacaatct
    50581 gcttgtttca taaactgatt cgttgctgcc cgcatcattt taggattgcc aactggatct
    50641 cctaaaacaa agcatttgtt tcctttgatc tgataaccaa aaacgacttg atcttggtcg
    50701 tcttcttggt aataaaaata actgtaacct gacaagcgaa gctgatggct tgtagctgtg
    50761 cctccgtatg tttccaataa acggtcaaaa cggtcttttt cgtactcact gccaagcttc
    50821 gtagtatctt cagctaaata ttgataaagc gccactaaag ctagcaatga gatgcccaaa
    50881 ccaataagcc ctgagaacca cacatcatct gaaggaaaca aaataaaatg atttcctgtt
    50941 attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa
    51001 aagccgaaca agctagcatc aaagattata gctccccaag aataaacgaa ttttgttcga
    51061 taaaattctt ttctggataa ccacacagct aacagaatca agacatatac caatatcaac
    51121 tgccaagata acgtacgtgt gattgtattt aaaataccaa aagatagtaa agcaatcgta
    51181 ggcagaaatg cctttttgac ttttactgaa agtgctctag caaggccgag taataaaaag
    51241 ccaaccaata gattcactgt ctgatctaaa aaattgaatg agaacggcaa taatacttga
    51301 aatagccgac tgattgcaga cagattagtg attgttgata gaagtaccat catgatcccc
    51361 gcaaaataga cagcacttac gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga
    51421 atgttatcta aaaatcgatt gattttgact cctgtatgtg tgatgaacaa tagaagtccc
    51481 gtcataaaag gtagaacata ataaaacaac cgataatata atagccaaac tactgctaca
    51541 tcttgccgaa cagacaattg actcattcct aagatcatca aaacgtcaaa agtccccatt
    51601 ccacctggga ccatcgtcag cattcctatc aatgtagcaa tcatgaacat aggatagatc
    51661 gaaagcatcg aaatatctat tctcatcaac ttgccgatga tcaaaaatac cgcaagggct
    51721 cccgtccatt gtccaaagga tgccagtagc agaccaagca agccttttgg ataaaactcg
    51781 aagaacaatg tctttctctt tagataagca aaaaagaaaa tgactggtgc taaaaaacta
    51841 ccgccgaaaa gccagatcca atagcttcga aaaatacttt ctgactgaat aaaaaagaca
    51901 tcaataaatg taagaaacga ccatacagac aaaccagtca gcataaatag tgcgactttt
    51961 gatacagtgg ctaaaaccat ttttctattt gtctgctttc cataaaaact agcccgcaga
    52021 cttgctccta ccacaccacc aaaaccggcg agattgttga tcgtgtttgt tacccacgca
    52081 gcaagaagaa actcttttct ttccattttt ggttttcctt gtttttctaa gactctgatc
    52141 gtcacccaat catacaacaa catcggagtg acacccagca gtccagccag aatcatgagc
    52201 aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa tatcttgcca actcatgcca
    52261 ttagcaatat ttgcgacttg atttgccaca aagactaaca cggagccgaa aaaaatcagt
    52321 tttaaaatca gactatgttc ctttatccat tgcagcatca agtatcgttt atttttcaca
    52381 ttttcccatt cctaacttgt atacttttgt gtcatacccc aatgttatct tatttatttt
    52441 aatttttcca ctttagacct gttctttgct tgcgatgata gaaaaagaaa gatatcctaa
    52501 tgctaaagga gaggataaca tgaaagtagg atttatcggc acagggaata tggcacaagc
    52561 tattattgat ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag
    52621 tggacatttt gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag
    52681 taatcaggaa gttgcatcac aatcagatat cgttctttta gccgtgaaac caaaaatcat
    52741 tgaaaaagta ttggaagaac taagagaata tagccagaaa gtcttattca tttctattgc
    52801 ttcaggaaaa tcattaatag atttagaaac agcgcttgaa gatcctcagg cctccatcgt
    52861 acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa
    52921 tgaagctgcc acggaggaac agcttcagca agctacgatg atttttgaag caatcggcag
    52981 cgtctatcct ttagcagaat cagatttcag tacattcatt ggccttgctg gcagctcacc
    53041 cgcattcgtt tacatgctga tcgatgcgat gggacggact ggtgtactga atggtttgtc
    53101 caaacagaca gccactgaga ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct
    53161 ttcaagtgat aaaaatccat gggaacttgt agaccaagtt tcttctcctg gcggtacaac
    53221 tgttgcaggt gtagttgcct tagaagaagc aggattcatc ccagcaatca tcaaaggaat
    53281 caatacgacg atcgagaaag atcttgagat gttgaataaa aaataatgat agcaatgttt
    53341 tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc gcggctcttc ttttgtattt
    53401 tttattattt agcataatca gttgcacgag tttcccgaat aacgattact ttgatgtgtc
    53461 caggataatc cagttcttct tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt
    53521 ctaaatccga gatttcttct ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg
    53581 cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt ttccagactt cttaaacgac
    53641 ggatgtagtt ttctaatgat tcacttcgcg caccaggtct tgctgctgag agcgcatctg
    53701 ctgcagctac aaggacagag ataacagaag tagcttccac atctccatga tgagaagcga
    53761 tcgcgttgat tactactggg ttttctttgt acttggcagc taattccgca ccgatctcaa
    53821 cgtgagatcc ttcaatctca tggtcaagtg ctttcccaat atcatggagc aacccggcac
    53881 gttttgctaa ttggatatct tcgccaagct ctgctgctaa gataccagct aattttgcaa
    53941 cctcgaccga atgcttcaag acgttttgtc cataactagt tctgaatcgc agacgtccga
    54001 tgatcttgat tagatctgga tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc
    54061 cgtattcgcg aatacgttca tccatttctt tacgagattt ctcgaccatt tcttcgatac
    54121 gcgctggatg gattcgtcca tcttgtatca gtttttccaa ggtcatccgt gcgatttctc
    54181 ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat
    54241 cgataccagt cagcgtctca agcgttcgaa tattacgacc ttctcgtcca atgatacgac
    54301 ctttcatttc atcattcgga agggtaacga ctgaaacagt cgtttctgaa acttgatctg
    54361 ctgcgcagcg ttgaatcgct aatgataata agtttttcgc tttgcgatct gcttcttctt
    54421 tggcacgctg ttcagattct tttaccatta gagttaactc atgattcagc tcttcttcag
    54481 tcgatttcat gatgacatct cgtgcgtcct cttttgataa accagcaatt ttttctagtt
    54541 ctttttgttg atcttcaatc attttttcaa cgtctttttc tcgctcttca attaattgct
    54601 gttttgaact aagtgcttct tctttacttt caagtgagtt ctcgcgtttt tctaacgagt
    54661 catctttacg attcagcgtt tgttcgcgtt gaatcaaacg attctcttga gattttaatt
    54721 ctaacttact ttctctcagc tcactttcaa cttcagaacg gtatttctga ttttcttcct
    54781 tagcttctaa caatgcttct ttttttagag tttctgcttc tttttttgca ctatcgatga
    54841 ttccagcagc tgatgattgt gcaccagcta tttctttctc gtgacgtgac tttgcgacca
    54901 taaaccctaa accaagaccg acaattaaac cgatgatagc gaggagaatg ttgaatacca
    54961 taaaatccac ctccatacta tctttttcat ttttatcatc tatacagctt ctatgataaa
    55021 ttattctaaa ctcgtcaata tgcatcttcg catatatgtg tacaaaaaac atgcacaact
    55081 ttattctaat gtttgtaccc cgtagtgtca actttaaata aacaaagaaa cggctttcta
    55141 cttattcatt aaacgatggt ttttaaaata aatgacacta gtttcatata ggtaaacctt
    55201 taaattgaga aacttttcta ttaaattatt ctttgtagat gaacagatat ttttatttta
    55261 tgtacccact cgtataatta aataactcac gatttcttta ttcaataaaa aaacggcagg
    55321 tcaaggagag tacctactct tcagaccagc cgtttttgtt tatcataatt tttattcttc
    55381 tactaaaggc aattcttctt gtcctttttc atcttctggg acagcgactt cttcaccaat
    55441 accataagct gctctaacta gagcagaaac ttctgccatc atttcaggat gattagccat
    55501 atagatttta gcgttttccc gtccttgacc aatccgatct tctttataag aataccaagc
    55561 accgctttta tcaacaatgt ctttttctac tgccatgtct agaagttctc cttcttgtga
    55621 gatccctaaa ccatacatga catctacttc agcgattttg aaaggaggtg ctactttgtt
    55681 ttttacgact ttgatctttg tacggttacc aacaatatct gtaccttgtt tcaattgttc
    55741 tgcacgacgt acttccaaac ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt
    55801 gatttctgga ttcccaaaca tcacgcctac tttttcacgg atttggttga tgaaaatagc
    55861 gattgttttt gttttgttga tcgaaccaga gagtttacgc aatgcttgag acatcaaacg
    55921 tgcttgtaac ccgacatgtg agtcacccat ttcgccgtcg atttctgctc gtggaactaa
    55981 agcagcaact gaatcgacta ctacgatatc tacagcccca cttgatacta aagcatcagc
    56041 gatctctaga ccttgttctc ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac
    56101 acctaatttt tgtgcatatt gcggatctaa cgcatgctca gcatcaatga aagcggccgt
    56161 tccgccattt ttttgtactt ctgcaatagc gtgtagtgca actgttgttt tacctgaact
    56221 ttcaggtcca tatacttcga tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac
    56281 atctaacgca agagagccac ttggaattgt agagatttgt tggtcgattt tttcgcccaa
    56341 tttcataata gagcctttac catagctctt ttcaattttt ttcagtgcag catctaaggc
    56401 tgctttacga tcatctgcca atacgataat cctccttata tttacaaatc agagcaacat
    56461 ttcattatcc ttatcatatc ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat
    56521 tcgcatttat cattttctta aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc
    56581 attatatctg atagcagcac gatctctggc aaagtgatat ttttccgaaa ccacgccgtc
    56641 tttagatgaa atagcgatcc atactgttcc tgcagattga ccttctaacg tgtccggtcc
    56701 agccactccg gtgaaagcta cactgtaatc tgttcttgct atctcacgtg cttgaatggc
    56761 catctgctcc acacattctt tgctgactgt tccatattct gctaatagct ccggatcaat
    56821 ctccagaaaa ccagcttttg tttggagcga gtaggtaacg aatccgcctg gaaatacttc
    56881 agatacacca gcaatgtcgc ctaatgcggc ttggaaggcg ccggctgtca aactttccgc
    56941 tgctgttaca gtctgcttgt tttctttcag tagttccact acgacttttg ctagcgaatt
    57001 atcatcgccg tatccataaa aatattcccc tactcgttct tggatttttt cttctaatgc
    57061 taaaagagct tgattccctg cctgaacatc atttgttttc actgtcagtc gtaatgtcac
    57121 ttcatttggt ttggcatatg gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt
    57181 tagctcagtg accagtcgcg attcaccaat cccataaaag cgcaaaactt tagaaattag
    57241 tttttcttca gaaggaaaac gttcctctag taaaggacgt acttgttcca caaacattgg
    57301 tttcaactca ttaggcggac cgggaagaag gatatacgca tgtgtatctg tttgataaaa
    57361 agtccctaaa gcaagccctg tacgatttgg tagaggaacc ccgccttcga taatctggga
    57421 ctgttgcaga ttgtttttgg tcatttttcg atgggttgtt tcaaaatatg ccaataattt
    57481 tttgtatcct tccgtatttt gtatgagaga cttaccgagg tgagccgcag ttgcttcttt
    57541 tgtcaggtca tcttctgtcg gtcctaatcc gccacataag agtatgagtt cacttcttgt
    57601 ttcagctaga gcaatcaact cttctaaacg ctgctgatta tctcctacaa ctgtttgata
    57661 ataaacttcg atacctagat cagctagctg ttctgacaag aaagtggcat tcgtattcac
    57721 gacttgtcct agtaaaagtt ctgttccgac agctattatt tctgctttca ttacttcccg
    57781 ctcccttata tagtatacgc tgtattttta tattttttta tttaaaaaga gggcaaggag
    57841 ctgtgacaaa aatcttgtca cagctccttg ttccaaataa acagtgttct cctgccaaaa
    57901 cctcggtcat aagtcacaat atacataaaa catgaaaagc tgttttttga aattatccct
    57961 tgtgactcag agttagacgg caggctcaca acctctccac taaacgatac ttacattgat
    58021 cctttgaaca caccgctgtt tttgatgaag taatccacac ctgaatagat agtaaagatc
    58081 agacaagcat aaagcatgat ttgatctact ggaataccga tcaggctgaa tgggatatta
    58141 ttgataaaca gcaagataat agcaaccatt tgtgtagccg tcttgacttt tcccggccaa
    58201 gctgcagcca tgacttctcc atgttcgaca agtagtaaac gcaagcctgt gacggctaat
    58261 tcacgacaga caatgatcgc tactacccaa ccaggggcct ttccttggtc aaccaacatg
    58321 ataaaagcag tcataactag cattttatct gccaacgggt ccgcaaactt gccaaaatta
    58381 gtgacaaggc ctcgcgcacg ggcaattttt ccatctaacc agtctgtgat actagctaaa
    58441 gcaaaaataa ctgcacctac tagctgtgtg acagccagtg tggtgtctcc tacgttaaat
    58501 tgtccccaat ctaaaggtaa acctacaacc aaaatgaaaa tcgggatcat acaaattcta
    58561 agtacagtta atttatttgg taaattcaca ctatcgactc ctttcttccc tattctacgt
    58621 gactatcagc gaagtttcca ccgatattat ttacttttcc aaatgaattt attcaaagga
    58681 gtatttttat tgaaattgat ctttttgaat taacgaagaa ggaccgcgac acagatttgt
    58741 cacgatcctt cttttttata cctacaagta aacagatgcg taaactaatt tatacgatca
    58801 ttctgcgtat tgaagagtaa ggttcacatt ttttggactc tgattgtttt cccctggatt
    58861 aactggtacg gattctccat tcgctttgat cgttgcattg cttgctgcac caatcgtgat
    58921 ggtcgcattt gttgctgttt ccggtaacac ggtactctgt gtttcatttg ctgccagtgt
    58981 cccttgataa acataggcat tgtctactag cacacctaac catacacgat tgacagcagt
    59041 aaattcaagg gttacaggct tggtagcgtc tgtgatattt actgcgatgg cactgccaga
    59101 atcttctcct gtagctattg ccattttctt ttcttcactt gattttgttg ttgattctac
    59161 tgtagaagac tctttggtct gcgtgctttg ctctgaggaa gaggactcct cgactgatcc
    59221 ttctacttta agcgaagaag ctgtgtctcc gattattgga tcagcttgac gatcttgcca
    59281 agtcatatag cccacgacaa cgacaatcgc caaagcaacc aatcctaata aaatgacagg
    59341 aagacttgtc caaaagcgac ttggatgcga ttcttcctga tgcattgctt ttctagaagt
    59401 acttactgtt tcaggctgcg gacgttcagg gaccgatcct gtcaatttgc ttttcccatc
    59461 aaaaacatcg actaaatggt ctccatcttc tcctacagct tcagcgtatt gccgaataaa
    59521 tgcccgcacg taaaatttac caggcaattg gtcaaaatca tcattgtcga ttgcttccaa
    59581 ataacgtttt tgaatttttg taatctgctg taattcatct aaagatattt ttttattcag
    59641 gcgtgcttgc cgtaattttt ctccgatggt ttcaaaagcc actcgttcat cttctccagt
    59701 ctgtttgatt ctccgaagca tctgctgttg caacgaaaga cgttatgttt gggtgctgtg
    59761 acaaaagtca tgtcacagct ccttttttcc gaataaacat tgttctcctg ccaactcctc
    59821 ggtcacaagt cacaatatcc aataaatata agaagctgtt ttttgaactt gttccttgtg
    59881 actcggagtt aaacggcagg ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc
    59941 ctcggtatta gctcaaaaac cggcaaaata taaggagata tttttccgta tgtttctcta
    60001 atactcaggt caaaacgctg atttcacaac ctcttcctta aacggtgttc aaaagcttgc
    60061 atctgcggta ataagtccaa ccaagttaaa aacattaaga agctgttttt acttggctgt
    60121 tcttattact tgatgcaggg cagctttttc acaacctctt ggtacacggt gttccagaag
    60181 tagcttcttc ggcaataagc cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt
    60241 ccttcttatt tcttgaagct gaccacttct gtcacaacct ctttgattac ttcgtttgat
    60301 tttattttaa tataagttga ttaaaagaga gcatgatttg ttttattttc tcactaattt
    60361 ttccaacaca actaagaata ccataaaagc tgattttgga ggaggttcct actacaagtc
    60421 taaaacgaaa tttaagactt ttcctcataa aatactggtt tattttggtc tcatgtaaaa
    60481 ctcgctgaag gcctcttcac ttataaatgc ttccccagct gccagtacgt ctttcatttg
    60541 gatcgaatcg atgatttcag gaagatcaaa taaagttcga tcgccaaata aactttgcgt
    60601 aaattgattg gcaatatatt cgatcgaatt taatgattgg aaatattgtc caagcatttt
    60661 cttcttcagc aaatcgagat ttgtttctga cacttccgga tcatcagcga atccaagaat
    60721 gatttctttg actttttctg ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc
    60781 aaagtgaaat tcacgatcca agctgaattc aaaaccaaag ctgtcatcga taattccttg
    60841 attgtacatc gctagatagt ttcgagaagt attgcctaaa atcatttgga acaacagatt
    60901 gattgctgtt ttatagcgta acagttctgt tccttcttgc ggcaatgtgt ctaatccttt
    60961 aataccaagt acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat
    61021 ttcttttgtg ttttcaggga aataacgtac aatttcttgc tttggaggga aattttttgc
    61081 ttcttggttt tcccgaataa gtttcatcaa tttctcaggc tccatcttac caactacaaa
    61141 taaaaccata ttgcttggct gataaaacgt ccgatagcac gtatacaagt cttgagctgt
    61201 gattttgtcg atactttcaa ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata
    61261 caagttattt agtatgccaa aaaacatccg ccagttaggg tcgtcttcat acatttggat
    61321 ttcctgaccg atgattcctt tttccttgtt tacagtttct tctgtgaagt aaggtgcttg
    61381 tacaaaatcg atcagagtcg tcagattctt ttctacctga tccgtcgtag aaaacagata
    61441 gctggttttc gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc caaataattg
    61501 aaagacatca ccatcttctt tttcaaacaa cttatgttct aaaaaatggg caattccatc
    61561 tggaactttc accttttctt tttcaccata gggaataaat tcgttatcga tcgaaccata
    61621 attcgtactg aacaaaccat atgtcttgtg atagtcattt ttaggcaaca aatacacggt
    61681 caaaccgttt ggcagtactt catgataaag tgtttcattg atttgctcat attctgtttt
    61741 attcatttgc atttcctcct gctaaaaaga agattgcctg caattcgatt tgctcagcta
    61801 cttgttgtat ctctttgatc gttacgctct ccatacgttt caaccattct tcatcagata
    61861 attttgtttc cggcagccag ctgtccaaaa aagaagcttc gattgccgct tgcggagagt
    61921 ctagagaaag cagatattgg tttctcagca ttgcttttgt ctgagacagt tccaactctg
    61981 ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt acttgatttc
    62041 ggttcttttc atcgataccg gtttggacac tcatgaatcc tcggaacgta tccacgctac
    62101 tagaggcata ataagctaga ctttctttct ctctgacatt catgaaaagt ttagagtgag
    62161 gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat
    62221 acacatttgt ctgataagct aggttcagct ttgcttgaac gattggctca cgtacttgtc
    62281 gttccttcac gatattcact tgaggttggg tataaaacag atctggataa actgtttccc
    62341 gcgactcaaa tggtaattgc ccaactgctt cagctgcttt gtccggatca acatcgccga
    62401 caacaaaaat gtcgatttga tcatttgcca tcatttcttg atagtaggac gctagcgaac
    62461 tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt tgttccgggc
    62521 tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa agtttgttta tcttccttca
    62581 aactttccaa atatagacgc agattgttct tttccaagtc aaacgtcaac tgatcaaact
    62641 gatgattttt aatatttgga taaaataaaa cctcttttaa aaaatctacc gcttgagaaa
    62701 aaaggtttgg atcattgaca tattcaccat tcacaaaact gatccctgcg tttagccaat
    62761 gtaaatttcc tttttttcta actgataatc caaagcttgc gccataaagc tctgcaagtt
    62821 gcgcacttaa ctttgtctga tccgaataat tcaaactatt tgtttccaac atgctgctga
    62881 gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc
    62941 ggatcgtttt gtattgtttt gttggtaaga catgaagatt cacgccttct gccaattgat
    63001 acaccatatt tatatgctcc ttttcacagt tgattgcccg cttactcttt taatgggtca
    63061 acctgccttt tttacttatt cctctgcttg aaatttataa gttcaggcaa ttcgccgttt
    63121 tttctaaatg atgttacact ttatagtata gcatagatgt tttttatcaa aagaaacaga
    63181 cggctaaaag cgtatattgt ttttttattt tttatttttc gatatactaa agacaaataa
    63241 aagaagggag ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc
    63301 ttggatcttg ctgtcggcgt tgttattggt agtgcgttta caagcatcgt aaaccaagtg
    63361 gtgcaaggct tgatcacacc actaataggt tggtttgtcg caatgatcac aggtacttct
    63421 gatttagaag gagcactttc aattcttgac tggtcgccga caaaaggcgt cacatttgcg
    63481 tttggtaacg ttattagtgc tatcattaca tttctgatca ctggttttgt cttattctta
    63541 gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca aagaagagca agtggaagtg
    63601 gaagaaactc ctactgcaga agattatctt agtgacatac gcgatcttct tgccaaacaa
    63661 gtggcagaag acaatacaca tccagtagag caaacaaatc tttccgatac ttctaaataa
    63721 taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg ctttcttttt ttagattctt
    63781 aacttgctac ttgttccttt ttcatgtcga tatgtggaat atcatcttcc aaatacacat
    63841 ctgagattgc cttgaatcca aacgactcat aaaaagcttg taggtattct tgtgcgccga
    63901 tcacgattgg tttttctgga aaatttttct ggatcatgtt aatcgtttct tgaacaatct
    63961 ttcttcctaa accatcttta cggttgtcct gatgaacaag gacacgtcca aaatggatac
    64021 tctccgcttc ttcatatact cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa
    64081 acgtatgcca agcttctcca tcaatgtcat caacttcttg ataaggacac tgttgttcca
    64141 caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt
    64201 caaatttctt tacctgatat tccactaagc aaacgccccc tgctttttta ttcttagcat
    64261 accgattcgc acacaaaaaa gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta
    64321 aactgcttca gttaaaaatt cgatctcaac tgtccgagta agtacatctg aatagctgta
    64381 agatactcgt tcaaaagaat tttcttcagg atccaaatca acaacgaata ctgaaggata
    64441 ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa
    64501 catgattggg ctgccgatac gaccttctaa atctttcttg attgaagcta aagttgttgg
    64561 catacagttc acctctacta tcaactatac cacatatttt taaaattttc aagtttacca
    64621 taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc attaagattt ttctaaatta
    64681 ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc cgtaagcgct
    64741 cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat caacgccttg
    64801 catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc aattttcgat
    64861 tgcttctttt aataaaagat gctgaattgc taaaggttct tgcaatgtga tctctgctaa
    64921 aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt tttgatcacg
    64981 acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta taacgctttt
    65041 ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg cctgatataa
    65101 agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat aataggtgtt
    65161 tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc
    65221 accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc ataaattcgt
    65281 ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata tgttatttat
    65341 tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct tcattccatg
    65401 gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct attgtttttt
    65461 ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct ccttgggaaa
    65521 agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat
    65581 tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa
    65641 caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt tgggcatcga
    65701 agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga tgtaaaagag
    65761 cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc ggccacgaac
    65821 caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac tccccctgac
    65881 gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt aagctctgga
    65941 cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat cctggactca
    66001 ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc catttttgga
    66061 agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg agctgttgca
    66121 cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag
    66181 tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc acaccatcga
    66241 cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat
    66301 ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc agttggtcaa
    66361 gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc
    66421 tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt tcacgtgcga
    66481 tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag agtttattcc
    66541 ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa ttatcttcta
    66601 atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt ttatttgaat
    66661 atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt gttctttctt
    66721 tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc catccgctcg
    66781 gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc gacccgatac
    66841 gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc tctgcgataa
    66901 taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat caaaaaggct
    66961 tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg ttttgtttct
    67021 ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc aacataagcc
    67081 aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat cgggttcctt
    67141 gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc
    67201 ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt tcaatctctt
    67261 catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat tgcgagaata
    67321 aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga taagtgttca
    67381 gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa tcatcgtcca
    67441 tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc gcatcatctg
    67501 ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc
    67561 gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc ggacgacggt
    67621 attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg atcatttcat
    67681 gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg ccaatcgtta
    67741 catagccatt gtgcatccag taattagcga attttttccc tgttttcgct tcactttgtg
    67801 cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg atatcgatcg
    67861 tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg ggacgtcctt
    67921 tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat aaagcgaaat
    67981 ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct ccgacttcca
    68041 gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg gtacggtaat
    68101 acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga ataaatgcta
    68161 aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggttcg acattcaacg
    68221 ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt gctgtaatac
    68281 ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc gatacgaaat
    68341 cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca atggtgctac
    68401 gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac ataccgacat
    68461 gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg tagattttta
    68521 tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg gtactcctac
    68581 cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga ttttggcgtt
    68641 ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg ctccttgttt
    68701 aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa
    68761 taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca ttccatggtc
    68821 gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag ttaggaaacg
    68881 ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata aaaaatgaga
    68941 gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct cagctgtcga
    69001 acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc aactcatgac
    69061 tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa gaaaagaagc
    69121 gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac ttttcttcat
    69181 aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac tttgtttcct
    69241 ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag gcatttcggc
    69301 aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca gctgcttact
    69361 tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg atttttcacg
    69421 accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg atacagctac
    69481 acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa cagctttgat
    69541 ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg ctttgaatgc
    69601 gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt cattcaatac
    69661 aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat agctcatttg
    69721 aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat ctgggttttc
    69781 tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg catctagatc
    69841 cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg
    69901 tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt cgaagatttc
    69961 gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg catctggtag
    70021 atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac gtttgcttag
    70081 ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca
    70141 gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt catctccacg
    70201 taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat tataagttgg
    70261 cataccatcg cgtttttgga tgacaaagtc gccaccgata ttatcggatt cgaacgaaat
    70321 agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac ggaaacgtac
    70381 aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca agttcgcaca
    70441 tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa
    70501 ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct gatcaatcag
    70561 cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc caggattttc
    70621 aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc ttttttcgcc
    70681 atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt ctccatcatt
    70741 gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat gcaggtgccc
    70801 agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac
    70861 tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat catttattta
    70921 aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa ctggttgaat
    70981 ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt ttctctgtct
    71041 cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag
    71101 cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg taatgctgtc
    71161 catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt tggcgttctg
    71221 tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact ggttttacgg
    71281 catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag actttattca
    71341 agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg atcaatttgc
    71401 tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat ataccctctt
    71461 ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt ttcaaactat
    71521 cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc atcaaggttc
    71581 cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc acgcttgtat
    71641 ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt tgactctcaa
    71701 cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact ttcttccatt
    71761 cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc atcagtaaaa
    71821 tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc gagatcacaa
    71881 cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa gtcaagctga
    71941 cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg gccaacagca
    72001 aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta ttattcagcc
    72061 atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa atacccaagc
    72121 ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt
    72181 ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta
    72241 ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt ttaggtaggt
    72301 atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata tgactgacac
    72361 gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt
    72421 tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct ggttcattta
    72481 attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc aacccagctc
    72541 ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct gttgttgttc
    72601 gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc aaaattggac
    72661 gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg cgttcttcta
    72721 agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc
    72781 caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga aaactatgat
    72841 gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt cttgggccgg
    72901 cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca tttgttttag
    72961 cggttttgag tagttctgca gtggtttctc ttacttggct gacacttcct gccacacttg
    73021 tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca ggggagatat
    73081 gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa aattctgtgt
    73141 tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct tcgccggata
    73201 catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac agcaaagtgg
    73261 atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc acacctccgc
    73321 ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt ttagggacga
    73381 cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga gttctgcggt
    73441 ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa tttgggcagc
    73501 gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt acttttgatt
    73561 tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc aagcttaagt
    73621 atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag cagtcgtttg
    73681 atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct cgcctttttt
    73741 gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc cttcatttgc
    73801 ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg
    73861 cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc
    73921 tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg atacatcttt
    73981 tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc agatacttgg
    74041 aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg tagcgcgctg
    74101 cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc tttttctcac
    74161 cggttttcct ccctaaataa actactccta ttctaacata tccgaggctg taaaagactt
    74221 tctttacaaa ttcttcaaga aattctgcta tcttaaagta aaccattaat tcgttctttt
    74281 tccaaacgac tgcaagttgt acaaaaaaac tattttttac atgactttac tcgtcaaaac
    74341 aagtagaata gaacgaaatt aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga
    74401 aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca agtacattga tttatcccaa
    74461 tggaaatatc aatcttgcgg caatcgatca gttagctttt gtcctttctg atcttagaaa
    74521 tcggggaaag gaagtgatct tagtctcatc aggagctgta ggcgttggta tgcataaatt
    74581 acatttgtca gaacgtccga ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca
    74641 agccgaactg atgaatatct ataatcaaag attcagtgta tataatcaac agacggcaca
    74701 gatcctcgtg acaagagacg tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac
    74761 attggaacag cttttgatta tggacacgat ccctatcgtg aacgaaaacg atactgtagc
    74821 agtggatgaa ttagatcatc tgacaaaatt tggcgataat gatcagctgt cagccatcat
    74881 ggcaaaactt gtcgcggcag accttttgat cgtcctttct gatatcgacg ggttttattc
    74941 agataatccg actacaaatc ccgaggctca gatgtatcgc tatatcgata aaatcgatga
    75001 aaagattctg gcacaagcag gtggtgctgg tagcacattt ggaacaggcg gtatgcagag
    75061 taaattaaaa gccgcttcta ggatatttga agcaaacagc gcaatgattt tagcaaatgg
    75121 aaaaaatccg gcaattattt ttgatattct tgcaggaaaa gaagtaggta ctttatttaa
    75181 ggaggacttg aaatgactga cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa
    75241 caactagcac ttatgcctac aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc
    75301 atcaaaaaga atcaacaagc gatcattgaa gcaaatcata aagacttaga aaaagcagtc
    75361 gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc tgacacctga gcgaatcaat
    75421 gccatggcta cagagatcga aaaaattgct tcgttagacg atcctattgg aaaagtagat
    75481 gagatgtgga cgaacaccga cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg
    75541 atcggcatca tttacgaatc tcgtccaaat gtcacgacag atgcagctag tctagcattc
    75601 aaatcaggga atgccgttat ccttcgcggt ggcaaagaag cattcttctc gaatcaatta
    75661 ttagtccaat tattgcagca agtactggtc agtgctggcg aatctcctta tgccatccag
    75721 tttgtcgatg atacttctca tgaaactgca ggacagttga tgcgattgac agaatactta
    75781 gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg
    75841 gtacctatca ttgaaacagg tacaggaaat aatcacgtat atatcgataa agaagcacag
    75901 ttatctatgg cagtgaacat catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac
    75961 gcggcagaaa cattgctgat ccattctgag atcgcacctt ttttcttgcc agctattgaa
    76021 aaagaactgg tagaacacgg ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta
    76081 gagacggctg ctttagcaga agacacagat tgggatactg aatatctaga ttatatcctt
    76141 gctgtcaaag tggtcgattc tttggatgaa gcaattgcac atatcaatcg gcataatact
    76201 aaacattcag aaacgatcgt gacagatagt tatgcggcta gtcaacgttt cttaaatgaa
    76261 gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt ttacagacgg atcggtattt
    76321 ggttttggtg cagagattgg tatctctact caaaagttgc atgcccgtgg tccaatgggg
    76381 ttaaatgaat taacttccac aaaatatatc atttatggcg atggacaaat ccgcgaataa
    76441 tgtttcgtgt gaaacattat tcccgccttt tgcctttttt ctgtaaaggt tctatccaac
    76501 tagaaaggtg tcaatatgtt tgaaatttta atgatttttt ttatttacct tatttctctg
    76561 aatatcgctg cttttctggg agtcggtatt ttatcccttt tctttcaatt caaaaaacga
    76621 agcataggga gtcaacggga aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg
    76681 ctggttacac gcttgcacat tagttacatg gttgcattat gcttattagc gacaatcaat
    76741 tactattctt ttttcgatca ttcaatcgct tatacgatta cgctactgat tgctgggatt
    76801 tttcacttat cttataaata tcagctgaat aaaaaccact tgaatcggac tttccgctaa
    76861 aaaatatccg tacgataagt agagtgcctt gaagatcggc aaaaaactgc cggacttttt
    76921 agaggctgtg acaaagattt tgtcacagcc tctttttcca tataaacggc gttcgcctac
    76981 cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg
    77041 ccatcataat aacgaagcag ctcatccatg gacaagttca tcgttttttc tttttcttct
    77101 tccgctgatt cagccagtag ctgttcccga tacacctgat acataccagc tattttttgc
    77161 tgcatcgctt ttctagtttc accttccgca ttgattattg gcaattcttt gatatagcca
    77221 cgataaatca accgatcatc tgaaaattca atgggtaatt caacgagtgt caacccgact
    77281 tcctgaaaat attcttccag catctattat ccccccattc tttttcttaa atgaatttta
    77341 gcttacctac tgaaaatttt ccagtttcat tattttgaga aaaaaaggga atgtgacaaa
    77401 aatcgtgtca catccccttt ttccgaataa atggtgttct tctgccaact cctcaatcat
    77461 aagtcacaat attcaacaaa catgagaaac tgttttttga aattgttcct tgtgattcag
    77521 agttaaacga cagtctcaca acctcttggt aaacggcgtt caatcagctg accctcggta
    77581 ttagctcaaa aaacggtaaa atatgagaag ctatttttcc gttttgtttc tctaatactt
    77641 aggataaaac gctgatttta caacctctgt taaacggtgt tcaatcagct gtccttcggt
    77701 attagctcaa aaaacggcaa aatatgagga actatttttc cgtttgtttc tctaatactc
    77761 aggacaaaac gctgatttta caacctcctg ataaacggtg ttcaaaagct tgcatctgcg
    77821 gtaataagcc caaccaaacg aaaaatatga gaagctattt ttgtttggct gttcttatga
    77881 cttgatgcag gacagctttt tcacaacctc tgatttctta ttcttcttca tttgtagcaa
    77941 aataattacg gtgataaatg atacaacata cactgataag aacaatggca cctgcaaaat
    78001 aaaacgcata gctttcacca atatgttcac caatcacacc tgcaataaat ggtgctaaag
    78061 ctccaccgaa aaagcggaca aaactatagc tggacgaagc aacgtttcgt tgcagacctg
    78121 gtatttccat agcaatcgtc gtcaacagtg tattgataat tccttggaaa aatcctgcta
    78181 acacaatgct gatcggtaca aggactggca tagaagttcc agctcctaat aacagcaaac
    78241 aaataatgaa taagacaaat gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa
    78301 gagccggtgc aacgaaaatc gaagcaatag ccagaagcac accccagcca aaaaatacaa
    78361 aaccgacttc taattcagaa tagccaatca ataaaaatgg cgcatacgca agtaaagtaa
    78421 agaatccgaa attatataac aatgcgatta gtccaactga acgaagttta tgattgctta
    78481 acgctttgac accttcccaa aggcctactt ttctctttgg tttctcagtt tcaggtaaaa
    78541 gtaccgctag ggctataaaa ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac
    78601 gccatgaacc actgcccaag accccaccga ctagagggcc aacagccatt ccgcagccaa
    78661 gtgctgcttc atacatcatg attgcttttt ctgtgttacc aactaaaata ctgacgatcg
    78721 ttgctaaagc agtagagaca aataaagcat tcccgacacc ccagccggca cgtaacccaa
    78781 tcagcattcc gatattccca gataatccgc caagaccagc gaatacaacg atgataaaca
    78841 atcctgtcat caatgttttt ttcaaaccga tccgactaga taagaaacct gtaaatagca
    78901 tcaccacacc agtgactaac atgtaactag taaataacag ggtcgtttca gctggcgtag
    78961 cgtttaactg tgcagcaatc gtttttaaga ttgggtctac tagacccact cccataaaag
    79021 cgatcataca ggtagctgct acaactagcg ctgaactttt cccctttgtt tcttcatttg
    79081 tttgttcttg tatatctatt tgattctcca atatttccat ccctttctct ctattagcat
    79141 catacatgat ttattttaca tgtcaatatg cacatgtaaa acgtggaaac tttactgtga
    79201 tataataaag aaaataagac gagaggtagg atttttatga atactttagc ctatatatta
    79261 ttatgcgtgc ttttatccaa accacgttct gggtatgaat tgaagcagct gatcacaatt
    79321 ttttgggaag cccatcacag tcagatctat acaacgcttg ccaagttaga ccagcagggt
    79381 tatgtgaccg ttttggacaa agacgagcac tctcaaaaaa agatctacca cttgactgat
    79441 gaaggacgtg ctcttgtaga ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa
    79501 gatgaatttc tagcaaaaat ctatgctttt tcgacgctcg ataaaacaac agctactgga
    79561 ctgctattca ctagagaaca acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg
    79621 aatgacctct cgctagacaa gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga
    79681 attatgcttt gtcagcagga actccaatgg tgtcagcaag taagagaaca aatgcagcag
    79741 ttttttgagt aagggataaa cagaaccttt ctagaaatat ctattgaaga gcaaattatc
    79801 ttcaataaaa gagcaataca gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc
    79861 tatcgttcgg atcactattt ttctagaact gcattcaaga gactatgaca aaaagcatgc
    79921 caaggccttt tttcaaataa cagtgttcca tcattcatta ctttgaattg cttttagcac
    79981 acttcttgaa agcgggccaa cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat
    80041 tttccaagca ttcatataag cagagaataa ttgatcaggt attccttgtt ccatgatcac
    80101 accgaataaa gacatacatg tcaccattcc taaaaccatc aagcatgaaa tagttaagat
    80161 catttggacc ttgctttctg gatttactgg tagtttaaag gcaatttttt tcgccagcac
    80221 accgatgatg aagacatcca aaatgaaagc caccacgaat ccaggcacta gaccaatcaa
    80281 caaacttgat aaatgaagat cttgatgcag ccataaatta tacgcgctca tccccaagac
    80341 catcaaaaaa cacatcattg ttgtaaaaat tattccttct tttttatttg taggcaatct
    80401 gtaccactcc tttaaatttg tcacgaaaat catcgtagca catttaaaaa tttctcgtaa
    80461 gtactttttt tattttctgc ccttttattt cataaacttc atcagccgta cgctcgacaa
    80521 agtaagaatc atgagaagta aacaaaatcg ttcccggata tatttgcatt agcttctcta
    80581 aagcttcgat cgttgccata tcaataaaat tagtcggttc atctaacagc aacacattac
    80641 ttggcttagt aaaaagcaaa gcaatcgtca gacgggtcgc ttctccccca cttaatgtac
    80701 ataacggttt cgtcaaagtt tcctgagcaa accctaagtg attcagcaaa ctacggacaa
    80761 gcgattctga aaactctgtt tgtctcatga caaaacgaat gatggattct tcagatgtca
    80821 tttgataacc cttttgctga tatacttgaa agcttacttt cggagagaga aggattcctt
    80881 ctccttgttt gcggatatgt tctaataagg ttgtcttacc tgaaccattt tcaccgacaa
    80941 tcgcgatttt tttacctaaa gaaaactgaa aatcaccatt taccagtaat gttctcccac
    81001 ttctttccaa ttggacattt tgtcccatga tgggatagcg gctgtggagt tcaagagatt
    81061 ttggtactgg aaaacggatt tgtttcatct gctgcggctt ggttgtttct cctatttttt
    81121 ggagtcttct ctctaatgtt ttcgcattct tttggatggc tttttgtaca ctgtcttttt
    81181 gtttagagga agacaaccga tccagtctga tttgttgctt tttcttttta ctggacactt
    81241 tttccaactt ttccgcttgt tttttctttt cttggatcga tttttccaat cgttttttct
    81301 ctttcatgat cgactctgct tctcgtagct gagtcttttt ctccaattcc ttttgagtga
    81361 gataggcact ataattcccc gaaaactctc ggatttctcc gtcttttact tcccagattt
    81421 tcgatgctag ctcatctaga aaatagcgat catgactaac aaaaaccagc gtaccataat
    81481 aataacgaag ctcttcaatc agtcgatcaa tactttttct atctagatgg gttgttggct
    81541 cgtctagaag catcccttgt tcataagaag aaagaagacg tatcaactcg atctttcgtt
    81601 cttcccctcc gctccatttc cgctctgaag tttcttccag tcttaactgg aaatgactgg
    81661 ctaattccaa atttaggtcc tttgcttcag cgagataggt taattgaggc aggtagttga
    81721 aggtgatctc tgtttggatt ttcccatgat cgggaaaaag ttcaccggct attagtttga
    81781 gcaaagtcga tttaccgaca ccattttctc ctatgatccc tatacgatct tgctgataga
    81841 cacgaagaga atcaatagat agttctagct ggttgccaaa gctgacttgt agatttgtta
    81901 tatttactgc taaattttcc atatgtttta cactcctatt tcatgtaaaa caacaattat
    81961 cgatactaaa aaagagcaga aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta
    82021 ctctgaacga aataactatg actaaatcac caaatctgtc atagctttca cctattctac
    82081 tgtcgttcga aaaaatggac atactccatc catgaaattg ttgtttatac atgtcttttg
    82141 aatttattta gttgttattc aaaagttcga aacgtaattt catcgatgca gtcatttttc
    82201 cgacctcctt ttttattagg ttaccacaca cgattcaaaa aaagcaatag ctactgaata
    82261 gtaactgaaa accttttatt cgaacatagt gatcttttct ggtgctaaac gaacagactc
    82321 gtaaccttct tctaccgctt ttcctattga taaaataata actggaacat aacggtcttt
    82381 atccaaacca aatgcctctg ccaactgatc tgcttcgaat ccaccaattg gatttgtttc
    82441 atagccatga tcacgcgcaa ctaacatgaa ttgcatagcc gctaagctag aatcgacttt
    82501 gactacatcg ttcatttctt ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa
    82561 ttgttgatct ctgacttctt ttggcatctt ccctgattcg taagcttggt tgtagatttc
    82621 ttcgccatat tcgtaacatt gcatatcgcc aaaaatcatg accattgcag aagaagtatc
    82681 attttgtctc gtattgaaac ggatcaaagg acgcaagatt tcttttgctt cctcgctttc
    82741 agcgaccaca aagcgccatg gtttcatatt gacagaagaa ggtgcagtcg tcgcttcttt
    82801 gatcatttcc agcatttctt cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga
    82861 tcttctacca gtcataattg ttgaaaaatc atttttttgt tccattatta ttaacctctt
    82921 tcgtttctgt tgttatattg caaagttggg tattcaattt atctaaaagt gttagaaatt
    82981 gtttcatttc tacatcgctg aaagccgggg atagcacgga acctgtatct ttatggtcca
    83041 tttcacaatg cttgattttc ttctgggctt tttctgttag cgctacatac acttcccggt
    83101 tgttctgagg atttctctga cgcgaaacat agccatttgc ttccaatacc ttcagatgac
    83161 gagtaactgc tccttgatca atctgcaact tttcttgcaa actgctttgt agcaatggat
    83221 tttcttcttt cagtctcatc atgatctcgt atctagtaag acttataccg atattttctt
    83281 caaagatctg gacgattttt tgatcggcta atttgatttg atataaaagg tgactaatct
    83341 cttctaaaga cataatttcc tcctttctaa taattgactc gtcaacgatt gacttgtcaa
    83401 taatagaata aaaaaagaaa aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc
    83461 aatagaaaag tatagagaaa agaaattttt tgtagaatga acggaaaaaa tgataaagaa
    83521 agcacaacgc taaaaccaag attattgatt cttatcaaac tatagaagat agctcttctg
    83581 cagtagataa ttttacaccg ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg
    83641 aatattagaa attggatcag tatgcttaaa cagtaataaa aaagttatga caagatgttg
    83701 tcacaacctt ttttgagtaa acggtgttca aaaacttgca tctgcggtaa taagttcaac
    83761 caaacaaaaa acatgaaaat ctgtttttgt ttggctgttc ttactacttg atgcagggca
    83821 gctttttcac tacctctttt taataaccat aaaatcctat tccttcatat ctccagccca
    83881 tcggtgttag ccaatctctt tccttagcac tcaaggtata gtgatgggta ccagtttttt
    83941 catttggatt aaatagtcga taaattggct tggaaccacc agaataaaaa cttagacctt
    84001 cataacgcca accgattttt gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat
    84061 ggtctccact gtaaggattg tataaacggt agacaggttg tccgctgttt ggtgcttgcc
    84121 aagcaatccc ttcatattcc cagcctacag ttggcagata atttttttct ccggcattca
    84181 atgtatataa atgttctcct gtatgacggt tatacagacg atacatcgga gaagttgaag
    84241 ttggtgctgt atcatactgt gtcagattat aggtttcgat tacattgttc aatgtagaac
    84301 cataattagg cgcagtggca taacgacctg ttagccaagc cgtagcatct ttgtaagagt
    84361 tcgtattgct tttccatgca ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct
    84421 tcaataccgt tacgttatct tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg
    84481 cattcaccgt aatccattgc ccattcacat attccgaagt aggcatcgta acagattggc
    84541 cattatagct tcctttaatc ccaaatagat tgtaattagg ggcagaagcc aaagtactgt
    84601 tcccccagcc actttcaacg atggcttgag caatcatgac tgatgcatat aagtcattgg
    84661 cacttgccaa actttgtgca gttgaggcaa tactatcaat gaacgcttgt tgagaattag
    84721 cagatgagcg agcataaaaa gcatagccag tatagttttc gaattcagac aaatctgctt
    84781 gatgggtatg tgtcaatgtt tgcccatctg tcaattggtt cgtgatttct tctgcattct
    84841 ctggattgtt ctgagcttct gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt
    84901 cagttgttgg ttcttcggtt gaaattgtat tttctgagac agtagctgac tgcaaagtac
    84961 tttctgtatc gttttcaatt cctgtttctg aagaactcga tgtctgagtt gcgacagttt
    85021 ctgtcgattc ttcagctagc actgttgtgt tggcaactgc tagatttcct aaaagaataa
    85081 cgctaaataa taaattcttt gctttcatct tttttctcct ttgaattatg aaacttttcc
    85141 taaataacag tgtaactaaa aaagtaaaag caagtcaatg tccatattta aataacattt
    85201 gtttcttttt aataaatttg ctttttctgc ataaaaagac gtaaatgaag aatattcttc
    85261 tccattcacg ccttaaattg atggtcgttt gaataactat ttaacaagta attctctctg
    85321 gatattatcc gttatggatt atacttcctg tgtcgtcgga cggataatca tgttgctgac
    85381 agacatccgg tctggcgttt ctatcgcaaa tgctacagca gaagctatat cttcagatgt
    85441 taatccccat tctttttgcg cttcatgaag ttcaagagca gcctttttgt cgctgatggt
    85501 ttgatataat tcagtttgaa cagctcctgg agagatgatc gtagatttga tgttattttg
    85561 ccgttgctct tgacgtaatc cttccatgat tgcacggaca gcaaattttg ttccgcaata
    85621 aacggcggaa tcaggataaa caacatgtcc cgccacagaa tcagttgaaa tgatatgccc
    85681 agatttttgt ttttccatga ttggaagtac ggcggaaatt ccatttaaca cacccatgat
    85741 gttgatatca agcatatttt gccattcatc acggtgacct tcaactaatg gagcggttgg
    85801 catgattcct gcattattgt acaatacatc gattcgaccg aacttttcca tcgctaaatc
    85861 gataactgct tggacttgtg caaaatctct tacatctgct gtttgaatat atagctcagc
    85921 ttctggtaaa gattctttta ttgcttttag gcgatcttct cggcgtgcag ctataactag
    85981 tttagcccct ttttctgcta atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc
    86041 catgatgaca atcacttttt ctgataaatc attcattcta ttctcctcct gttttgaaaa
    86101 atctcttgct tatactcact atctcttatt tcatcttact gttcaaataa tccgttcgac
    86161 aggtttgacg attttggcag ggattcctgc aacgatggta ttgtctggga catctttcgt
    86221 aacagttgca ttcgctgcaa caatggcatt ctcgccaatc gttacgcctg gcagaatagt
    86281 tgctcctgct ccgatccaag catttttctt gatgtggatt ggctttactg acaagcctct
    86341 tcgttctttt ggatcggtta gatggttcac cgtgatgagg ttgacacgag gaccaatcaa
    86401 tactgaatct tctaaacaga tgccacctaa gtcaacgaac atcacttgac gattgataaa
    86461 gacatttttc cctatactaa tatgtttgcc gaaatctgta taaaaaggca gcagaacagt
    86521 caccgtatca tctactttgt cactaatgat attttctagc cgtttgcgga tatctgctgg
    86581 ttcatggtac ccagtattca gcgctgctaa aggctcttcg ttttccgctt ggatctgatg
    86641 gatcacttca aagagcggat ccgttactcg aatctcttta ttgacgattt gtttttcgat
    86701 gaggcttgtc attttgctcc ctccttttat ccttacttta taacggacgg cttatgatgt
    86761 ctaatactta taaaacatac ttaactattc cttttaacta tacttagtgg tatgcttttt
    86821 taaaaacagg agggaaaaaa tggatattcg tatactgacg tattttttag cagtagctag
    86881 agaaaaaaat atcagccgag cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa
    86941 acaactgaaa gatttagaag aagaacttgg tgtgacactt ttcactcgag gctcccgaga
    87001 gatacagttg acggattctg gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt
    87061 ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc atctctggag aaatctacat
    87121 tggcggaggc gaaactaaag caatctcttt catttctgat agccttcatt cgttgatcaa
    87181 ggcgcatcct gatatccagt ttcatttata tagcgggaat gcagatgata tcatagacaa
    87241 actggatagc ggattacttg attttggact cgtaatcgaa ccgacaaaca aacaaaaata
    87301 ccagtcattt cgactgccag cccaagatcg ttggggactt ttgatacatc ggaatcatcc
    87361 tttagcaaag caaacagtca tccatccgca ggaactgaaa actgttcctt tgatcatttc
    87421 ccggcaaacg tcagtggaca gtcaactagc tgaatggcta ggtttcagca tagatcagtt
    87481 atcgatcgtc ggaacatata acttattgta caatgcttct ttgatggtcg ataacgggac
    87541 ttttggtgca ttagctctag atgggatcat caatacttat gggacggaaa aagtattcat
    87601 cccactcgat ccgccattac aagcttcact gaatctcatt tggaaaaaag accagcctct
    87661 ttctcctgct gctcgtaaat ttttagatgt cctaacggag aaatacagtt aagtagagtt
    87721 tttttccttc gctttcagct ttttaacaac gaataagtta agcaaaagat ccaatgatta
    87781 aataacataa gtttcttaat ttgttccttc cttttatttc tgataattcc agtaaattac
    87841 tataattata aaaaaagaat tgacaaaaca taactgtcta tataaaattg attacgttaa
    87901 caataattcg tttcatgtga ctagatcata ctaggcatga aaaatctctg aggaacatgg
    87961 tttccctagg aggtttttcg tgtctatttt tgtttggccg caatcaactg gtctagcaaa
    88021 cgtgaaaacc aaatcttcaa aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa
    88081 aatgcagtat tggtagatga cggtggacag gaaaaagtag ctattggaaa agggattgga
    88141 tttgacagaa aaagaaatga tttgattttt gatcgtgatg tcgaacggat atttgtcatg
    88201 gaaccagaag gtcaaatcaa gttgcaaaat ttacttaatc agattgatga acgcttttta
    88261 tttgcagcag aaacgatcat tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa
    88321 catgtattga tcgctttgac cgaccacatt gctttttctg cggagaacat taataacggt
    88381 atcgtcatcc gcaacaaact tttaagagaa atcgaagtgc tttacagtga tgaattcagt
    88441 attgctcaat gggcagtaga gtatctgaca aaagagcttg ggattccata tacttatgac
    88501 gaagcaggat atatcgcaat ccatattcac agcggacgaa gcggtcggaa caataaccat
    88561 cgcagtatcc gtgaagtgac gattgtatct gacatcatcc atttagtgga atcagaattg
    88621 gaaacagata tccattcaga accattttca ctgaattatt caagactggt gaatcattta
    88681 cgactgcttc tacaacgaac ccatgcgcaa caatatgctg ttttagacac ggaaatcgta
    88741 gaaatggtca aacgaaaata cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg
    88801 ctgaccaaag aataccagct cgcgatcacg aaagaagaac tgggttactt ggccatccat
    88861 atcgagcgtt taagaagcgc aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa
    88921 aattgaaagc atatctacaa cgaatgggac gttcccttca acttccagtt gcggtcttac
    88981 ctgctgctgc tttactagta gggatcggaa actggtgggc atcttatagt aacgacattg
    89041 tcgctcattt tttacaagct ggcggtaacg cagttttagg tcaattacct ttgctgtttg
    89101 ccgttgggtt agcactaggg atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt
    89161 tggtcgcatt tgaagttcca gtaaatgttt taaaaactga ttcagtagct actttattga
    89221 atatcaaacc agaatcagtt gatccatctt ttgctcagat cagtaacgta tttattggta
    89281 ttattgccgg attgattgcg gcagctcttt ataatcgttt ccacgaagca aaattaccga
    89341 tggctttatc tttctttagc ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt
    89401 tgctgatcag tgcagtgcta ctgctcgtat ggcctccggt ttactctgct ttagtttctt
    89461 ttgctaaatt cattttgagt ttaggctggg gtggtgcagg tctttatggc ttcttcaacc
    89521 gtttactgat ccctacagga ttgcatcaag caatgaactc cgtgttctgg tttgacgtag
    89581 caggaatcaa tgatattggt aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa
    89641 tgtatcaagc tggatttttc ccaatcatga tgttcgggct tccagcagga gcatatgcta
    89701 tttacagaaa tgcacgtcca gaaaacaaag caaaaacagc ttccttgatg ttagcagcag
    89761 cttttgcttc attctttact ggtgtaacag aaccacttga attctcattt atgttcgttg
    89821 cttggccatt atatgtcttg catgcaattt tcactgggat ttctttagca gtgagtgcat
    89881 tcttccattg gacagcagga tttgccttta gtgccggatt tgtcgattac ttcctatctt
    89941 tgaaaaatcc gattgcgaat cagccattga tgttgatcgt ccaaggatta gtaacagcag
    90001 tgatttacta ctttggcttt aactttgcta tcaaaaaatt ccatctgatg actcctggcc
    90061 gcgaggaagc agatctttca gatgacgata ctgcaacgac taattcagac aataaatatg
    90121 cggcacaagc aagcaaaatc tacgctgcat taggcggagc cgacaatgta acttcgatcg
    90181 ataactgtac tacacgcctt cgtttgcaag tcaaagatac aggcctgatc gatcaaaata
    90241 aaatcaaagc cactggcgta cctggtatga agatcatcga cggaaaaaat gcgcaagtca
    90301 tcgtaggtac agaagtacaa ttcgttgcag atgagatggc aaaactacat ggtggtgctg
    90361 caacacgacc tgcacaaaca aacaccgtgg ttaaaacaga aacatttgcc ggtggaacga
    90421 tcgaacaaga tatttacgct atcgcaaatg ggaaactgat tccaatcact gaagtttcag
    90481 atgatgtatt cgcggaaaaa atgatgggtg acggctatgc tgtattacca gaaaatggag
    90541 aaatcttctc tccaatcgct ggtacgatca caaacatttt cccaacgaaa catgctgtcg
    90601 gaatccaaac agatgctggt atcgaagtct tgcttcatat gggcatcaac actgttgact
    90661 taaaaggcga accattcact ttatatgtaa aagaaggtca aaaagtcgca agaggtcaat
    90721 tgattgcttt agttgatctt gccgctattc aatctgcagg caaaaacacg gatatggtcg
    90781 ttgtattcac aaatggcgac aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa
    90841 aagcaaatga taaaatcggc tctgtttcca acaaagcctg agccatcgtc ttccccagac
    90901 ttttttatcg ataaacaaac aggagctgag acaaaaatct tgtctcagct cctttttccg
    90961 aataaaaacg gcgttctcct gccaactccg cggtaataag tccagccaaa cgtaacatat
    91021 gaagagctat tttttatttg actcttctta ttacttgatg cagaacagct tttttacaac
    91081 ctctgataaa cggtgttcaa aaaccagttt atcggtatga agtcaaattt atgcaaaaat
    91141 gtggaaagcc attttcacaa aatttttctt catactcaaa actaatcggc tttttcacaa
    91201 cctctttata cattattcct gatccaatat ttcttttaat gctgcttcaa gagaagttaa
    91261 tggttttccc aatacttttt ctaaatcatc agaggaaata gctaactgat cctttttaat
    91321 atcatgttgg atcgctaaaa acatgtcagc tgcttcttga gggaatccgg cttcttttag
    91381 attttcgaca aacgctgcat cacttgcttc aataatttct aactttttac ctgtcgcacg
    91441 ctctaatgcc ttggctaatt cttcatagtc agttagattg ccggataatt ctaagatttc
    91501 tggagagtca ctttctacta gtacttttgc tgcagcttct gcatattcac gtttcaatgc
    91561 ccaacctgtt tttccatttc ctgcagcata aacgaattga ccagttttta aagcctgccc
    91621 aatgataggt aattcattct ctacatacca attattccgt aaaaatgtat gggaaatacc
    91681 tgaatcctta atcatttttt cagtgaattg gtgatctggc gctaatacac tgatcgagtg
    91741 atcggcatct gcaaaacttg tataagcgat ataagatacc ccagctgctt gtgctgcctt
    91801 cactacattc ttatgttcgg cttgacgatt tcctggaacg ccagagacaa aaagcaatcg
    91861 atctattcct ttcaacgctt ctttcattga gtctaaatca tcataatcac caatacgtat
    91921 attaaatcca gcttctttca gtgcttctcc tttttcttca ctacgtacta gtacatagat
    91981 ttcattttgt ggaaccatct tttttaagaa ttccagcgca taaccaccaa aacctccagt
    92041 tgctcctgtt actaaataat gcatatttgc cactccctat tctttttatt tgttaagatt
    92101 tacagctgta catttataaa ttacaccttt atcataaaga gtgtggtaag ataagtcaag
    92161 caaaaaaaat gaaaggatga caactgatga agtattctct gcaatttagt gatgcaatcc
    92221 atgtacttgc ctatattgaa atgtttcaag atacccgatc actttctagt gagatgattg
    92281 ccagtagtat cgaaacaaat gcagcaaatg tacgtaaaat catgagtcag ctcaaaaaat
    92341 ccggtttgat ctttacaaaa accggaaaac cgcagccttc ccttgccaaa agtccagatc
    92401 agatttcttt actagatgtc tatcgcagca tcgaaggtaa tacacagctt atccaagtcg
    92461 atccaaaaac aaatccaaat tgcgtcgttg gtgcgaatat ccaagaagct ttagaagaaa
    92521 gctacgctcg gctgcagaaa aaggcagaag aagaaatggc taagatcaca cttgatagtc
    92581 tgatacataa aatagccgtt ttggaaaaag aaaaaagacc agaaaacaca ggcctcgtag
    92641 agagattttt ataattctct ctactgtgcc tgcatttttc tgatcggaat cgtctacata
    92701 aattctttta ttctccgggg gacaaaagcc ttgtcatgcc cctttttcct ctctaatgct
    92761 caggtcaaag cgctgaagtc atgacgtctt gataaacggt gttcaagtag ctgaccctcg
    92821 gcattagttc tgaaaaatgc aaaatatgga aagctatttc ccatttttcc tctctaatgc
    92881 tcaggtcaaa gcgctacttt cacgacctct atattatcat ggtttattga ctaccggtat
    92941 ccagatttct cccatatatt tcccgttggt aactcccatt tcgactacag catttggacc
    93001 cccaacatag gcgtaatctt ctacttctct taaaacatgc ccaaaggccg tattcgtcaa
    93061 atcatttctt aattcttcag gcgattctgc taaagcgatt acaacaagat acgttccttt
    93121 tgggaatggg atgattcggg tagtgtttgg aacatcctga ctcgtttgaa caccgacata
    93181 gtacatcatt ttcccgttat agggttcgtt gactgtaaag aaataatgat tttcagcagc
    93241 ttgtttcaat gcatctattg ttccattacc gataactttt tgctcaaatg cttgtttctc
    93301 tgcagccaaa ccgacaaaat ccgtattgct actcttcaat tccacaccaa tacccgtcac
    93361 cgtaaaatct ggtttttctt cgatcctata ctttgccatt tctcccaccc tttctattat
    93421 attaagttca tcttacataa aattaaaggg aaatgacacg attacgctct tttttctagg
    93481 gatattttta ttttttaact atttttttgc tttcactgca atccaaatct cactgtaaac
    93541 attactgaaa tcctctcccc attttgtaaa agagatctcg ggagcttcga ctaactcata
    93601 atctgaagaa ggaagccatt ctgcatagat tttcccccaa gtatcttgta aagtttgggg
    93661 aaatggccct ttattaggaa aaatggccca agtgtgttct tctatagcaa gcatttctaa
    93721 atcagcgtac ggattttctt ttgtcgtagc aaagccaatc atgtgcatca aactgccctt
    93781 ttcttccaag cgggctccat caaatccata agaaacgttg attacttgat ttggatataa
    93841 atctcctaac ttatgcatct cttccctttg agtctccgtg atcgtctgcg ctaacttttg
    93901 tatttcttga ttgactcctt caaatttgac aggaactttt ttcgccacac ctgccacata
    93961 aaactgttct ttcttttcga tacgaaattc catcgatttt cctcctctga catcaataaa
    94021 aaatgtcaag cgtggaaaag atttttgtat gccgtatctg ctgatttctg aaggcagata
    94081 tcctgaccaa tcacgaaaag ctcttgaaaa accttcgact gtttcatatc catatctaaa
    94141 cgccgtttct gtcactcttg atccatctag gagatcgcga ttagccaaag ccaatctacg
    94201 gtttttgata tagtccatta gcgacatccc tgcaataaac gtaaagatgc gttttaattg
    94261 atattcagag attcctgtat tttcggctat tattttatag gaaagtcctt ctgtcaaatg
    94321 ttcttcgatg taatcgatca attggttcag atctttaagc atatttatct tcctccttgc
    94381 ttgccttttt atcatattat caaagaaagt caattacttg atgaatcagg aaccaattta
    94441 gtcagatgta gaaaatgttg tatggatcta aagaaaattc tcaagcagcg tttcgtaacg
    94501 gataattggt attatctgcc tatctatgtt ttacctttag aaaaataaat tttggggaag
    94561 acacattcta agtaaacaaa gcggtaaaaa tatcttttat tcccttagtt aatccgctta
    94621 ctacctactg tacaaagcaa attgttgttc aaactgctga tcagaacgct gcttggattt
    94681 ttctttgcga tacatcatac ctcttttatc aattggaaca attatttatt tctaacaaaa
    94741 tcacttcatt tttgtcagat aaataaaaaa caaaaaaagt tccatcttta aaacacgcta
    94801 ttcttttact ttttctcaca ttctctaaga aaagaaaagg agaatgaatt tttgacaatt
    94861 cgagcaaaag tgattatcaa atatgtaaaa tcagctactt ttttcttaaa cgtttcttta
    94921 tactaaatat aaataagtgt ttcatgaaag gagaactaga tgaataattg gcttgagtat
    94981 tttcctgaaa acgttttgga acgcggttac agctatcatc tgcacggttt tgtccgtcat
    95041 ttgaactata caagcaagta cttgtccgca acagtttctg gcacggaaga ttataaggta
    95101 gtgatcactt gggatgaaaa gaccaacatg acttgtgatt gtctatatgc catagaagga
    95161 aaaaaatgca aacacatggc tgctgtctta ttcgcttacg aagaacgtcc aataaaaaaa
    95221 tccaactact cactttccga actctcgtcc cttgtttcct ccgctagttc ctctcttgta
    95281 cgggagcttt taacagagat tcttatagaa catccgcaat ttatcgaacg cttcaaagtt
    95341 aagatgccat ttcatgcaat aaattattca gataaattaa caactatcat ccataaatac
    95401 gatcatatta tcaagaaaaa caaaaacagg aaaacagcga agttcatcat ggagatgcga
    95461 aagttcatcc aagaagcagt tgaatcgctc attcagcaaa atgcctatct tcccgcattc
    95521 gaattgatca atgaagtgat tgctactctc gaaacattct attgggagcc tgaggatgaa
    95581 cgaacccttc ttctgataga ggactgttat tatttatgga aagaattatt agcagaagca
    95641 cctcatgcag aaaaaaggca aatgttctct tggttcgtct gccaagtcga tcatactgac
    95701 gcctcttatt caaaacgcta ctccataaaa atcctgaaag aagactttcg ggaaaaagaa
    95761 ttttctaacc aaaagaaaaa aatagataaa aaaactaaag aaacggtaaa gaaagacgat
    95821 ttcaatgaaa aatagcaagt aaacgataac aaccatccta aatccacaag aaatacagca
    95881 gaccttgctt taaaaacacg aatcatgcaa aggatgaagt aaagaagact taacgcgtac
    95941 ccaatattag tcatttgact attaggtacg cgttttgttt tataagtcat gacaaatttc
    96001 cttcgttgct gggtagattt tccggcattg ttgatagatt ttatgatact tttctacatt
    96061 ttgtaagaga ggttccactg catctgtata ttggataaaa ttctgacaac aactttcagg
    96121 tgtgtcgaac cactctaatc tttaaagata aatattaaaa taacgattaa taatattaac
    96181 agtctttatt tttcaccacc aaaaacctat ctttgcatat actaaataga cgtatataca
    96241 cagataggtt tgtcttgtga aaaataatga ttatccttac caaaaaatgt ttgtttttct
    96301 acatgttcgt acttatcaaa aaatatgatc cttattgaaa ttactggcta tttatattcc
    96361 aacgacttct tgtgttaatt tttgttatct catagtaaat tatgtttcat tttcacttaa
    96421 tttagttgtc acgtgttcgt caattcgtaa aaacggtaaa tatataaaca cacttgcggc
    96481 tataattaat atttgtaaaa cagctgctcg ccagtctccg gctgttgcta aaaatcccga
    96541 tataactggt ggcgtagtcc aaggaatttg cactactaca tgattaatta atcccacagc
    96601 agttgcaaaa tatgctactg tcaaagaaaa aatcggtgca agcacaaagg gaataatcag
    96661 actgatatta aatacaatag gcaatccaaa aataataggt tcgcttatat tgaatatagc
    96721 gggagttacc gataatttag caaagtcctt ataatctttt ctacgactga agataaatat
    96781 tgcaatcaat aaagcaatcg tatttcccga tccacccatt accgcaaagg tatctttaaa
    96841 ggccatattg ataatatgtg gaatttgctc tttgtttgca taagctgcca tattttcttg
    96901 catattctga atcaaaaacg gatctaacaa tgaacctgat attactgctt gatggatacc
    96961 aaatccaaaa aatagattag caatagatgt aattaacaaa aatcctggta aaccagttgt
    97021 aattttactt aatggctctg taactatcgt ggtaattagc ttatttatat ccatattaaa
    97081 caattgaatg attataaatg acaataaagc aaacgaggta atcgtaataa tgattgggat
    97141 taatacatta aaagacttta aaacagcggg aggaatattt ccggatagct gaatctgtag
    97201 tttcttatta ttagaaagtt taataaataa ttctgtagcc gctaatccaa caaatatacc
    97261 tacaaacatt cctgaagctc ctgtatagga tataggtatc acacccgtca cttcaacagc
    97321 tttatccgca ttttcaggag taaacatcat ctgcataggt gttaatacaa caaatgtcga
    97381 aatagcaact aataccgctg caatatgatt tgtataattt ctgcttgcac acatatgata
    97441 agatactgct gctacaacta ataatgtagt tatgcttaat gtaccattgg caattgaagt
    97501 accaatttgt tgtaacgtgg tcaatgtact agtatcgaca atttccccca tgaatcctgt
    97561 tggttctaag atcactgaat taataagtgt cacaaatcct gctaacatca taaatggcat
    97621 aaatgtagca aacgcatctc gcaaagttct taaatggatc tgattcccca acttagtcgc
    97681 aactatacca aatttttcaa atacaatgtc cttcctgcta cttttgccca tattttttct
    97741 cctttatgct tattgtaatc gattactttt tccacccaaa taatacatca cttatcaaaa
    97801 aaagtaaata cttttaatta aatatatata tcttttttag tataaaaaaa taagctctga
    97861 aaaaataatt ttcccgagct tatttttcaa caaaaacagc ttcaaaaaca aagtcttgat
    97921 ataaatgtct cgataccgaa tactcgaaag gtttaccaga cgatagagca acaactttgt
    97981 ctatctcaat cataaattca cctggatcta tttttaatat ttttgcgtca aattcattcg
    98041 cagtatctcc tttgatacgt atgtgcgaag tctttatttc cagacccagt tcatttgtga
    98101 tataagcata tacagatttc tttaaatgtt ttggttccaa gcctggtatg actgctaatg
    98161 gcatgaatgt ttgctcaatc gagtatggtt gacaatcaat aaaacggctt cgtacaatat
    98221 tatatacata gtcttttaca ctgatactta atttatcagc tacttttttc gatggaagtt
    98281 caattgagaa agtatggatt tctgaatcta cgtgttcttc accaaccacg ctaaacaaac
    98341 cttcgtttgg accaagaact cgtgagttat caattggtgt tctgacgact tcagtcccat
    98401 acccacttct acttcgcaaa actccttcgg aaacaagtaa gtctacgcct ttctttactg
    98461 ttaacttgct tgtatgataa ataactgcca attcatctcc tgtaggaagt ttctcaccaa
    98521 ttttatactc tccatttaca atttttttct ttatatctaa gtaaatttcc atatacttcg
    98581 caattttttt caatggtgac cctccaatca aaaacatatc ttcatctata ctttaacata
    98641 aataaaccga taaaatccac atcaaaatta tacacacaat aaaaaagata tatatattta
    98701 aacaaaacta tttactttaa gttgtaagcg gtgttatcat taagtggaaa caggaggtaa
    98761 aaaaattatg acaactatga aaaagctaac ttttccagat gatttttggt ggggttccgc
    98821 ttggtcagct gagcaagcag aaggaaaagg agaaacagga aaagcagaga ctatctggga
    98881 tcgctggttt aaagaacaac cttaccggtt ttatcaacga atcgattcct ctattacaac
    98941 cgatcacatc catcaatata aagaagatat agaactaatg aaaaaaactg ggcataactc
    99001 ctttcgcgtt tctatttctt gggcacgaat gtttccaaat ggcggtaccg gaaaagtaaa
    99061 tcccaaagcc atttctttct atcgaaaatt attttccgaa atgaataata acggaatcaa
    99121 agtatttgcc aacttatatc attttgacat gcctgctact cttcaagata aaggaggatg
    99181 ggaatcacgt gaagtagttg atgcttatgt tcattacgct gaaacttgtt ttaaagaatt
    99241 tggtgactta gtttgtcatt ggtttacctt caatgaacca cttgggccta ttttaggtac
    99301 ttatcttgaa gattttcatt atccaaacct cattgacttt aaacgcggag cgcaagcagc
    99361 attcttcact atacttgcac acgcaaaagc aatacaagta tttaaagaac tagctcttcc
    99421 tagtaaaata ggcgttattc taaatttgag tcctactttt cctcgtagtc aaaatcctgc
    99481 tgatgtgaaa gcagcagaaa tcgctgattt attttatacg cggagctttt tagatcctat
    99541 ggttaaaggg aatttttcta aaaagcttat cctgttatta caagaatata atcagcttcc
    99601 tgaagattat acgaaagaag atcttgtatg tatctacgaa aataccgctc aaattcttgg
    99661 actaaactat tacgagccac gtcgcgtcaa atctcgttct tctatggtgg atacatctag
    99721 tccattttta ccagagtggt ttttcgaacc acatatcatg cctggacgac gaatgaacga
    99781 ataccgggga tgggaaattt acgaaaaagg aatttatgat ttgtgcatgg atatcaagaa
    99841 ccattatgga aacatcgaag catttatctc ggagaacgga atgggcgttg cggatgaaga
    99901 acgtttcatg gatgatacag ggcaaataat tgatgattat cggattgagt atatcaaaga
    99961 tcatcttgct tacttatgga aggcaataaa tgaaggatgt aacattaagg ggtatcatct
   100021 ttggacattt attgattgct ggtcatggat caacgcctat aaaaaccgat atgggctggt
   100081 ttcactcgac cttactactc aaaaaagaac aattaaaaaa agtggcgaat tttacaagca
   100141 attaagtgat acaaatggat ttagatacga tgtagacttg ttagttgaat aatattctaa
   100201 aattccactt gaagtgaaca cattagaaaa caagaataat gagaaatacc aataacaaat
   100261 actttttctt catacttcat ttatacttgt cagtataaga gactgtgaca aatgtagtga
   100321 tcctcagaag ttaggtctgg aaatctaact tgagaagatt tttttaaact acgtccagtc
   100381 ttttttattt gtttaaaatt gaagttgaca agtcttcatt aaaaatttag aatattcaca
   100441 agtttgacga caattatgaa aatttatgtc gtgctaaagg agttttgtta ttggatgaaa
   100501 agttagatat aaaaactgcg atcaaagaca cgttacctac cgtttttggt tatatcggta
   100561 ttggacttgc atttggtatc gttgggaaag ctgccgggtt tcatccgctg gtcgtcacgt
   100621 tgatgtccct gctgatctat gctggttctg cccaatttat cacggtcagc atgcttgcta
   100681 gccatagtcc actgctctcc atcgttctct cgacctttct agtcaattcc cgaatgattc
   100741 tgatgagtat gacgattgct ccttatttca agaaaaatcg gctgcttcaa aatctgctga
   100801 ttggcacatt gctgacagat gaaagtttcg cactgggaat gaataaattg aactatactg
   100861 gacaaaagtt aaactttcgt tggatgaata cagctaattg gatttcttat ttgacgtggg
   100921 tgggttcttc tcttgttggc gcacttttag ggaattttat tactgatccg aaaaagtttg
   100981 gtttggattt cgccatcgtc gctatgttta tcgggttact ttatcttcaa gtcatttctg
   101041 atagaaacac ctctaaacga ttacagttga tcctgattgg tctcactttg attctggtat
   101101 atgtcggact gatttttatc ccaagtaact tagtgatttt agttgtaaca ctgattgggt
   101161 gcggattggg ggtgtggatc aaacatgcct tcttttgagt ttacattgct gactatttta
   101221 ggttgtactt tagcaacttg gctttctagg atcctaccat ttgtcttact gaaaaaattc
   101281 gatttgccgc aaccgttgct tgagtattta agttttgtcc cgatcgtcat tatgtctgct
   101341 ttatggttca gcagtctatt tacccaaaat atcggacatc tgccgcagat caatctcgaa
   101401 aatgctttgg cttcagttcc tacactttta gctgctattc tttcaaaaag cttattggtg
   101461 atcgtcttgg taggaattct ttccctttcg ttgattcgct tattataaat aaaaaaacaa
   101521 gagcttatgg caaattactg tcatgcgctc ttgtttttat caaagtcaaa taagaaaaaa
   101581 atcggcgtat tcttgcttat ccgttgaacg gaccactaac aacgactttt cctaatatat
   101641 gtcctgtttc tacgtctttg gttgcttgtt tcaagttctt cgcattcatc ccatctgaat
   101701 agaccttgct caatgtactg cggataatcc cttcatttgc taaagcagca atgtgcgcta
   101761 aagcttctcc ttgcgtttcg atttcatagt tatagtctgt tttagcgaac atatactccc
   101821 agtcgaagct gatagattgg tttttccaaa cacctatatc taacggctct ttgatcccta
   101881 cgatcgttcc cacatgtcca aatggtcgga caaggtgttt gatttgatca aagtagcggg
   101941 taatatcgaa taatacagcg acatactcta cttgatcgat tcctaattca cgaaaacttt
   102001 tacttaagtc gtgatgataa tcgattggat agtctacacc tgtttttttc agccattcaa
   102061 aattcttcgg acttgcagtc gcgtagactt ctaggccagc ccaatgcgct agttgattca
   102121 aaatcgaacc gacgccccca gctccgttga tcactaagat ttttttcccg cggttggcat
   102181 tttcttctgg agtcagacca aatttttcaa ataacaattc ataagcggtc aatgaggtca
   102241 acggcaaggc tgcggcttct tcatctgaaa gattttttgg tgcaagagcg acaatacgtt
   102301 cgtcaaccag ttggtattct tgattgcttc ctgctcttgt cgttgtacct gcgtaaaaaa
   102361 cgcgatcgcc gacagaaaat ttttgcactt catcacctac agcaacaact ttcccgactc
   102421 catcaaaccc taagatacgt aaagcatttc ttatcccgtt atcttggcga agtttcgtat
   102481 cgacaggatt aacagatact gcgttgactt ttaccagaag atcccgtgaa ctgggtacag
   102541 gtatctgttc tttttcatca ataaagcttt ttggatcatc gatcgacaac ccttcataaa
   102601 aaccgactac cttcattaat tccttttctg acatacgaat tcctccttag cttcatcaag
   102661 ttggagcatc catacagttt tcatttcaat atatatagta tgctatttgt tccactttta
   102721 ttcatcataa ttattctctt acttaaagta aactatttgc acttttttgg ttaaaaaaga
   102781 ggttgcgaca agacttttgt cacaacctct tttaaacggt gttcaatcaa ctgaccctcg
   102841 gtattcgctc aaaaaacgac aaaatatgag gagctatttt tgtttggctg ttcttattac
   102901 ttgatgcagg acagcttttt cacgacctct aattcacggt gttcaagcaa gaaatcattg
   102961 ttcactgaaa agcgttggat gttctttttc aaaggtgtct aagatctctc gtacttcatc
   103021 agtagatttc gtattcatca actgaactcg caagtcattt gctcctggaa atcctttgat
   103081 atagatttta aagaaacgat gtagtcctgt gatggaacgc gggatgattt ctgaataatg
   103141 atcttgcaga tctagttgca gacgaagtag tccgatcagt tctttttctg tatgttccct
   103201 cggttctttt tcaaatgcat aaggattctt gaaaatcccc cggccaatca tgatgccatc
   103261 tacgccatat ttttcggcca attcttctcc tgtctggcga tctgggatat ctccgttgat
   103321 cgtgatcagt gtttgcggag cgatttggtc acgtaaagca atgattttag ggatgacttc
   103381 ccaatgtgca tctactttac tcatctcttt acgcgtacgc aaatggacag aaagattggc
   103441 tatatcttga tgaagtaggt gactgatcca ttcttccatc tcagacattt ccgtatagcc
   103501 gatacgcgtc ttgacgctga caggcaaacc gccagcttta gccgcttcaa tcaattgtgc
   103561 cgctacttct gggcgaagga tcaagccact gccttttcca cgttctgcta cattagggac
   103621 tgggcagccc atgttgatat cgattccttg gaagcccatt tctgccatag caatgctcat
   103681 ttctctaaaa aattctggct tgtctcccca aatatgggca accatcggct gttcatcttc
   103741 tgtaaaggtc aatcttcctc gtacactgtc ttttccatct ggatgacaga aactgtctga
   103801 gtttgtaaac tcagtaaaga agacatccgg tgctgctgca tgctttacga catggcgaaa
   103861 tacaacatct gttacatctt ccattggtgc taaaacaaaa aaaggctttg gcagctcttt
   103921 ccaaaaatta gtagtcattt atttgttact ctccattcta tcaagcagtg aagtcgcaat
   103981 ctttctcaaa aacattgtca ttatactagg aaacaaaaaa agaagcaaag tgaacagctt
   104041 aaaagatgtt tctgattgag caaaaaaaga ctgtgacaaa aatcttatca caattccttt
   104101 tccggaataa atggtgttca aaagcttgca tctgcggtaa taagtccaac caaacgaaaa
   104161 ataggaggag ctatttttgt ttggctgttc ttattacttg atgcagaaca gctttttcac
   104221 aacctctcca ctaaacggtg ttcaatcagc tgaccctcgg tattagctca acaaacgaca
   104281 aaatatgagg aactattttc ccgtttgttt ctctaatact caggtcaaaa cgctgatttc
   104341 acaacctctt ttctaacttc tcaatcctct tcctttattg atcaaatacc aagtaacggc
   104401 gtacaaaaca acgatgaata gcacaagtac gatcatcgat gttgctactg gcacatcgat
   104461 tgttccaagg aatccgtaac ggaaaccgaa gatcatataa acgatcggat tgactttcga
   104521 aacagcttgc caaaatggcg gcaacataga gatggcatag aaaacgccac ctagataagt
   104581 taacggctgc aagacaaatg taggcacgat cgatacatcg tcataagact gagcaaaaat
   104641 cccgttgagc agtcctgcta acgaaaacaa gattgccgtc atcaataatg taatgatgac
   104701 catgaaccat gaatacacat gaagtggtac aaagaacaag gaaatgatcg ttacgagaga
   104761 gccgacgaga atactgcgac ccactccgcc aatcacaaag ccccaaatga tcacatgcgt
   104821 aggaacaggc gctaccaaga tttcttcgat gtttttctgg aatttttgag agaagaagga
   104881 cgaagaaacg ttggcatacg aactagtgat agcagacatc ataatcaaac caggcacgat
   104941 gaattccata tatgaaaaac cacccatgtc accgatccga ccaccgatca tttttccgaa
   105001 aataacaaag tacaaggatg tcgtgatcac aggcggaacc agtgtttgga cccagatacg
   105061 caaatagcgg ttcgtttcct tgatagctaa actttttaat gcagtaaaat aaagattaaa
   105121 catttttctc ctccgtatga ttattttctt ctgtgatttt caaaaacagt tcttctaaac
   105181 gattcgactt attcctcata gaaagaactt tgattccttg tcttgtcagc tgatcgaaga
   105241 ttccgttcac cccttgattt cgttcaactt cgacagcgat tgtctgttca tcttcaaatg
   105301 tacaagcgta tccttcaatc acaggtttgg tctcatatgg cgctaaatca aagataaatg
   105361 tttcaaattg cagtttggat agaagctctt tcatactagt attctcgatc agttcacctg
   105421 attggatgat cccgatgttg cgacaaagca tttcagcttc ttctaaataa tgcgtcgtca
   105481 aaatgatcgt tgtaccattt tcgttcaatt ctcggagaaa ctcccacatc tcgcgtctca
   105541 attcaatatc gactcctgct gttggttcat ccaagatcag caaacgtggt tcatgcatca
   105601 atgccctagc aatcatcagt cttcgcttca ttcccccgga aagcatacgt gcacggacat
   105661 ttctcttttc ccaaagattg gactgcttca aatatttttc gctgcgtttc atcgcttctt
   105721 tgcgagagac accgtagtag cctgcttgat tcacgacgat ttgctggacc gtttcaaagg
   105781 gattgaaatt gaactcttgc gggactaatc caatctgttg ctttgctcgg actagatccg
   105841 tatccagatc ataaccgaag acattcactt ttccagatgt tttattgact aaagaagtaa
   105901 tgattccgat cgttgtagac ttcccagctc catttggtcc taatagcgca tagaaatctc
   105961 cttctttcac ggaaagatcg attcctcgca atgcttcgac cccacttcca taaacctttt
   106021 tcaaattatt tatttcaagc gcatttgcca tttatttcct atctccttat agacatgatt
   106081 ctttattgta tcatggaata cagcagatga aaaaacaact tggttccagc gaaaaatcag
   106141 gttgctgggc tcaggaaaat ctcctaatga aagacatcaa tcggacgaag tcagacaacc
   106201 ttttcagaaa aaacaaatcg aagataaagg attactattc atatgtgcaa caaaaggagc
   106261 gtgagacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag
   106321 caaaagccaa gatttttgat ccaataaata ctttcgatca cttcgcctat cccaatacat
   106381 gccactgccg cttttcatca aataacgcgg cttccgtttt tgcggtttct actaaagtct
   106441 ctgggtaatc caaaactttc agcaaggcaa tcgcatttcg ggtccttgaa ggtccttctt
   106501 ttaatttgaa atcaaaactg attccttttc cttctgttac ttgttcttca aagtggacat
   106561 tctcacaata attctttaaa atctctgtca attcgatatc atgtgtggcg acaaatgcta
   106621 aagatggata ctccgcaagc caccgaacga ctgaagcgga agaagcaatc cgttcgatcg
   106681 tatttgtccc ttttaaaatc tcatctacga agcagtagca gcgttctttg gaagccactt
   106741 ggtccaacaa acgtttgatc gatttgattt ctgaaacaaa ataactgtcg ccttcaaata
   106801 aatcatcttc gattgccatg gaagtcaaca catgtccagg ttgcagggta aactgttctg
   106861 caatcgctgt ttggatcgtc tgtgctagaa tacagctgat ggctatactt ttgacatacg
   106921 tagattttcc tgatgcattg gaacccgtga ctaatgtatt cttctgccag ttgaccggat
   106981 tcactaccgc ttcttttaac aatggatgat agatatcttt cgctgtcaca ccgccctcag
   107041 taaactctgg tcggcaagtg atgggcatat aagtacggta attcaatatt gcagcggcta
   107101 cttctaattc tcccagcaat tcccacagct tgatggcttc agttgaatgc ttttctaatt
   107161 tagtgagaac gaaatgatag gagataaatg gcagcatgaa catgatgttg acatattcaa
   107221 aaatcaactc tgcttcactc ccactcttca tacgaaatga aaaacctaat ttagggatgt
   107281 ctcttaatgg tttagtttgc tgtttcagct cttcttgaag tggtgtcggc agttttgcta
   107341 gctgattggc ggctgaaatc gttgaaacca aataactcat gctattcagc tctgtttcta
   107401 gtgtttgttt cttcactaga taatagaccg tattgaatac taacccaccg attgccaaat
   107461 agattcctag tacttgtcct aaaagaagca aacccaaacc caccagcgga agcaagccaa
   107521 gaaaaataaa taaacctacg cgtccaatct ttttactttt tccatccgct agatattgtt
   107581 ttgcaaaatt atgatctttt tttcctaaac gagcgaattg atattggatt ttttctctca
   107641 gttgaggatt ttcctgataa aaagcaatca gtttttctaa ctgctgatct tcaccaaaat
   107701 caaagctgcg taaacgttga tacaacgctt ctgaacctac actagaatag gtactgttga
   107761 ttccttcgaa tacttcgaac atatccaggt cataccaagt aagatcatcg atttcgctat
   107821 cccatgaacg gaacttcttc tccgtgagcc atgcttcctt caagctttct tctttatcaa
   107881 atctcggttg ataaggaatt ttttcccatt tgctacgaac tgtttccttt aatttcaaac
   107941 gtgaaaaaat gtctaaagca actaataaaa taacagctgc aataataatt aaaacgataa
   108001 attctctttg acccatatcc ctctccgttc ctttatttgt tagctttagt atagcactgt
   108061 tgcgctattt gaaaagaggg taaaaaaaca cctttcaaaa taaaaggtgt ttttttcttg
   108121 tatattacat atttatctct catttatcaa aattgacaaa taatcatagg gaggaattgt
   108181 tgttaattct tgtttattct ccagtgcatt gacaactgtc ccaagggaaa ggatagcctc
   108241 aggtactatt ttttcttgtt ctgttggatt agctaagcga agaacaaatc cttgttcatg
   108301 aaaataagaa ggataaatcg atgatacaat taagtcttca ggtaattcaa tcaatgaaaa
   108361 tttacgagga acatcaagtt cattttgtaa tggccaaatc ttgttatcta acctgtgaat
   108421 aaatacattc agtttctgct tttgataaga aatagattgt tctaaccgtt tttctgcctg
   108481 ttttgccact ttgaactcat taaatcttcc ttcttctaca ttaaatccaa aagtgacttt
   108541 atactcacct atctcttgag ctagcggtgt ttccatcatg acatgccctt catttgtcgt
   108601 atctcctgaa gctcgcccag gtcgccaagc aagattaggt tttccaagtt cccctgttgt
   108661 tgaaaataag gttatgatta attgattttc tatacgttca tactctttta aaccatctgc
   108721 ataaaacgta aaataatgat cattttctgc cacagagaca ctcttatcga atatttctaa
   108781 attaacaggt ttctctacca tagtttctga ccaattcgga ggaatgacat caggggtatt
   108841 ttcaataaat ccgttttgaa tttgtgcaat tgatttttca gatttatcta aaacattaat
   108901 tgctaagcgc atacgatgcg agtaaacagt attatgaatt ttgagtgtgc cttcaacgat
   108961 ttgactttct cccagactga acgatatttc ataagatatt tcttccattt cgggtttttc
   109021 agataaacga tcttttaaat ctttaggaag ttgagctttt ccgtaaacaa ctaatgtttc
   109081 ttgtaaagaa tctttatata ctttagctgt ttctaatttt agagatagtt ctgtatctcc
   109141 ttctaatggt gaataatcat acgtatcgcc atcatttgct gaatcgatca aatgaacgaa
   109201 atcaagatat tgtctatctc caactatcaa attcaattgc ccatctttaa aagaaagttt
   109261 atatttattg ttacttatct cagttttgtc tatctcgatt gctgtttcta atttttcatt
   109321 atttttctca aattcaacaa cagtgtatcc tagtgctggc acatttacat ttatttttat
   109381 gtcaagttca taataagctg gttcatcaaa atattcgaaa cctgtagcaa tcatccgata
   109441 agcatttttc cgttctggaa aataaacttc tttttcaatg atattatagg gactaccttt
   109501 gaagtgtatt ttctttgaat cagctactac atgcacgatt ttcgatccac tataattctc
   109561 agtcgttgtg ttgaaaacaa ggacttcatt cgattttagc tttaatgcat cagccatccg
   109621 ttttacaata aggttttcga ttccgtcagc tatctcatta gcttctttga ttcgatggaa
   109681 aatatcttcc gcaacattat ctgaaacaca gccaccaata ctatcatgag cctggttttg
   109741 caaaatcttt ttccataacc gacgaagtag gcctttactg atatggatac catttctttc
   109801 tgcaatcagc atgagcggct caactcgttt tagaattttt tgttccaatt taaaattttc
   109861 tattttcatt tttgttctta ctgagccaat agaacgatga acacgagagt aaaccggctg
   109921 acgaagttca cctttatatt caggtaattc ttttttgttt ctgataactt ctacataaga
   109981 aggataatct gaaataatat tgtggaattt actgtattta ttcaacttct ctacgacttg
   110041 atcaaaattt aaaatcattg acttttgatc tacacccgaa ggtactaaaa tatctttgtt
   110101 ttttccttgc atatgaagca tttcaactgc ttcatccaac ttttcttttg caaattcagg
   110161 aatatcttta attgcgtcta aggtcatcat tccagtcata taaccaaatg gaaaattcat
   110221 ggcataaaca aatttatctc ccaatccttt ccagataaaa taaggagatg gaaccatcgt
   110281 ttcaaagttt aatcctcgcc aacacatgaa attatcgatt tctacttgat gcaaaagtgt
   110341 aggcaaattc gcattgaacc caaacgtgtc aggcaaatac cctaccatca ttggatctcc
   110401 atatttaagg atcgtatcac tgattccaat cattaagttt cttaaaattg attcagcatc
   110461 cactaataag gcatctgttt gtgcatacca cggtcccacg aatagttgtc ctgttttcat
   110521 cagtcgttgg ataaccttaa gcttttgcgg attgatctcc aaatactcat cgacgattga
   110581 agtttgtcca tctaaacaaa agtttacttt agggttcctt tccaattcat ctagaacttc
   110641 agtaaagacc tgatcagaca atacgatggc atcttcattt gtaaaatacc attctctgtc
   110701 ccagtgcgtg tgttgaatta tatgtgcatt taccatatca gattctccta ctttccttct
   110761 tctactgaat ttacttgttg ttctttttta tacttgatgg attttagtgc attgaccatt
   110821 aacgctgtaa ccactccccc aataacaatt gatactaaat ataaaggtat attcgtaaca
   110881 aaaggaattg ccataaaggt tgaaagcatt gtttcttgag taacaccaaa aaatccattt
   110941 agaccacatg ctactgcagt gcccaccacg atgcttggta ttactcgtaa aggatctttc
   111001 acggcaaacg ggatcgtccc ttcagtaatc cccacaaggc ccataatcat agctgtcttt
   111061 gcattatctc gttccgattc atcataaagt tttttgttta aaattgttgc taaaaacatt
   111121 ccaaatggcg gaatagcaat tcctaataac atggctgtac taggtccaaa gcttccgctt
   111181 gaaaaagaag caaccccaaa agcatatgcg attttattga taggtcctcc catatcaaac
   111241 gccatcattc ctcctaaaat agccgacatc aaagcagcat ttgctcctga catgccttct
   111301 agccaattag tcagtcctgt tgtcattgct tgaataggcg tagctagtac ataccataat
   111361 atgattccaa caactaatgt agtaacaaaa aggaatcagc ataattgatt ttagactaat
   111421 aacttgcatc ggtactttta cttttttcaa tgcattagct aaatagccac aagctaatcc
   111481 agcaaccatt cctccaataa atcccatacc aagattttga cacatcatcc cagtgataaa
   111541 agctggtgct agaccgggac ggtcagcaat tgaatatgcg atataggctg aaatcatcgg
   111601 tacgataaac tgtaatcccg tctgaccaat cattcgcagg actccccaga atgtatccgt
   111661 ctggtcccaa acacctgtgc caccaaaaat gactgcaata gaagttagta accctgctgc
   111721 tacgacaagc gggatcatat aggaaacccc actttggaaa tgatttagaa tttctcttcc
   111781 ttgtttcttg aattccatta gtaactcccc cacgatatat tttttatttg ttaattaatg
   111841 caattgcttc atcaatcgtc tcttcaccat cttttactac ctctgaggtc cctactgtta
   111901 aaatcggttt accgtcaaag cgacctcgtt ctgaaacatt tgtatctact gcaaatatga
   111961 caacatctgc ctcggaaaca tccgaaattg aaagtttgtt ttctatcccc atagccccct
   112021 gtgtttctac tttaatatct aaccctttct tcttcgcaaa cttttctaaa ttagcttttg
   112081 ccatataagt atgggcaatc cctgcgatac atgctgttac tgctactatt tttgtcatat
   112141 gaaattcctc cttttaaaat gatagagctt ttaccaattc ttttttattt ctcgaatctt
   112201 ttattctttt aacaaactcg tcatccatca atcttccaga taattctgct aaaatacgta
   112261 aatgattagt acctttatca gtgtctttta ttgctaacaa aaagacgaga tcaactggtt
   112321 gatcatctaa tgcgccccat tcaacagacc gctttaactt ggctacagcc actgttgatt
   112381 caattactgc taggcttttg ccatgaggaa tggcgatatt tttcccaatt cctgtggtca
   112441 tatggttttc tctgtcaaat acgtcttttt gaaattgttt gtggtcagac acaaacccat
   112501 tagtctctaa caatttcgat aatttttcga ctacactttt tttatcagat gcatttaaat
   112561 ctatcactat attatttata ttgatttttt cactgatcat ttataagcct tctttcaata
   112621 tataaactaa tttttcaaac gacgaactcg tttttaaatt tgctaataac tcatgattcg
   112681 aagcgatttc attgaatgtt tcataaattt tattca
//
LOCUS       DAZKNV010000002        94436 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000002 DAZKNV010000000
VERSION     DAZKNV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 94436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.002"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            166..981
                     /gene="thiD"
                     /locus_tag="ACG8M1_000103"
     CDS             166..981
                     /gene="thiD"
                     /locus_tag="ACG8M1_000103"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFQ0420857.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1186..2637)
                     /gene="cls"
                     /locus_tag="ACG8M1_000104"
     CDS             complement(1186..2637)
                     /gene="cls"
                     /locus_tag="ACG8M1_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFQ0420858.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            2979..5645
                     /locus_tag="ACG8M1_000105"
     CDS             2979..5645
                     /locus_tag="ACG8M1_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0420859.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6009..6761
                     /locus_tag="ACG8M1_000106"
     CDS             6009..6761
                     /locus_tag="ACG8M1_000106"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0420860.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(6783..7937)
                     /locus_tag="ACG8M1_000107"
     CDS             complement(6783..7937)
                     /locus_tag="ACG8M1_000107"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFQ0420861.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8122..10563
                     /locus_tag="ACG8M1_000108"
     CDS             8122..10563
                     /locus_tag="ACG8M1_000108"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFQ0420862.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(10893..11597)
                     /locus_tag="ACG8M1_000109"
     CDS             complement(10893..11597)
                     /locus_tag="ACG8M1_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420863.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(11784..12029)
                     /locus_tag="ACG8M1_000110"
     CDS             complement(11784..12029)
                     /locus_tag="ACG8M1_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420864.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12046..12897)
                     /locus_tag="ACG8M1_000111"
     CDS             complement(12046..12897)
                     /locus_tag="ACG8M1_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0420865.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13063..14067
                     /locus_tag="ACG8M1_000112"
     CDS             13063..14067
                     /locus_tag="ACG8M1_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFQ0420866.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(14308..14664)
                     /locus_tag="ACG8M1_000113"
     CDS             complement(14308..14664)
                     /locus_tag="ACG8M1_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0420867.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            15032..16219
                     /gene="tuf"
                     /locus_tag="ACG8M1_000114"
     CDS             15032..16219
                     /gene="tuf"
                     /locus_tag="ACG8M1_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFQ0420868.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(16407..18998)
                     /gene="mprF"
                     /locus_tag="ACG8M1_000115"
     CDS             complement(16407..18998)
                     /gene="mprF"
                     /locus_tag="ACG8M1_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFQ0420869.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(19024..19785)
                     /locus_tag="ACG8M1_000116"
     CDS             complement(19024..19785)
                     /locus_tag="ACG8M1_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0420870.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            19952..20584
                     /locus_tag="ACG8M1_000117"
     CDS             19952..20584
                     /locus_tag="ACG8M1_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFQ0420871.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            20643..21503
                     /locus_tag="ACG8M1_000118"
     CDS             20643..21503
                     /locus_tag="ACG8M1_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFQ0420872.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            21688..24003
                     /locus_tag="ACG8M1_000119"
     CDS             21688..24003
                     /locus_tag="ACG8M1_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0420873.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            24185..26026
                     /gene="dnaG"
                     /locus_tag="ACG8M1_000120"
     CDS             24185..26026
                     /gene="dnaG"
                     /locus_tag="ACG8M1_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFQ0420874.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            26050..27159
                     /gene="rpoD"
                     /locus_tag="ACG8M1_000121"
     CDS             26050..27159
                     /gene="rpoD"
                     /locus_tag="ACG8M1_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFQ0420875.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            27376..29517
                     /locus_tag="ACG8M1_000122"
     CDS             27376..29517
                     /locus_tag="ACG8M1_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFQ0420876.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            29713..30576
                     /locus_tag="ACG8M1_000123"
     CDS             29713..30576
                     /locus_tag="ACG8M1_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFQ0420877.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            30681..31154
                     /locus_tag="ACG8M1_000124"
     CDS             30681..31154
                     /locus_tag="ACG8M1_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0420878.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            31250..32137
                     /gene="xerD"
                     /locus_tag="ACG8M1_000125"
     CDS             31250..32137
                     /gene="xerD"
                     /locus_tag="ACG8M1_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFQ0420879.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            32156..32527
                     /locus_tag="ACG8M1_000126"
     CDS             32156..32527
                     /locus_tag="ACG8M1_000126"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0420880.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            32524..33294
                     /locus_tag="ACG8M1_000127"
     CDS             32524..33294
                     /locus_tag="ACG8M1_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFQ0420881.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            33278..33847
                     /gene="scpB"
                     /locus_tag="ACG8M1_000128"
     CDS             33278..33847
                     /gene="scpB"
                     /locus_tag="ACG8M1_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFQ0420882.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            33853..34569
                     /locus_tag="ACG8M1_000129"
     CDS             33853..34569
                     /locus_tag="ACG8M1_000129"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFQ0420883.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      34651..34775
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            34898..35509
                     /locus_tag="ACG8M1_000130"
     CDS             34898..35509
                     /locus_tag="ACG8M1_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0420884.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            35887..37410
                     /locus_tag="ACG8M1_000131"
     CDS             35887..37410
                     /locus_tag="ACG8M1_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFQ0420885.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            37647..38987
                     /locus_tag="ACG8M1_000132"
     CDS             37647..38987
                     /locus_tag="ACG8M1_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0420886.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            39141..39878
                     /locus_tag="ACG8M1_000133"
     CDS             39141..39878
                     /locus_tag="ACG8M1_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0420887.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(40043..40264)
                     /locus_tag="ACG8M1_000134"
     CDS             complement(40043..40264)
                     /locus_tag="ACG8M1_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFQ0420888.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            40295..41326
                     /locus_tag="ACG8M1_000135"
     CDS             40295..41326
                     /locus_tag="ACG8M1_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0420889.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            41313..42716
                     /locus_tag="ACG8M1_000136"
     CDS             41313..42716
                     /locus_tag="ACG8M1_000136"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFQ0420890.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKHQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            42782..43417
                     /locus_tag="ACG8M1_000137"
     CDS             42782..43417
                     /locus_tag="ACG8M1_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFQ0420891.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            43465..44145
                     /gene="cmk"
                     /locus_tag="ACG8M1_000138"
     CDS             43465..44145
                     /gene="cmk"
                     /locus_tag="ACG8M1_000138"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFQ0420892.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAIQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            44280..45509
                     /gene="rpsA"
                     /locus_tag="ACG8M1_000139"
     CDS             44280..45509
                     /gene="rpsA"
                     /locus_tag="ACG8M1_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFQ0420893.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            45691..47001
                     /gene="der"
                     /locus_tag="ACG8M1_000140"
     CDS             45691..47001
                     /gene="der"
                     /locus_tag="ACG8M1_000140"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFQ0420894.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            47244..47519
                     /locus_tag="ACG8M1_000141"
     CDS             47244..47519
                     /locus_tag="ACG8M1_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFQ0420895.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            47754..48800
                     /locus_tag="ACG8M1_000142"
     CDS             47754..48800
                     /locus_tag="ACG8M1_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420896.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQRPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            48802..50061
                     /locus_tag="ACG8M1_000143"
     CDS             48802..50061
                     /locus_tag="ACG8M1_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFQ0420897.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIAPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            50067..50648
                     /locus_tag="ACG8M1_000144"
     CDS             50067..50648
                     /locus_tag="ACG8M1_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFQ0420898.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(50730..51605)
                     /locus_tag="ACG8M1_000145"
     CDS             complement(50730..51605)
                     /locus_tag="ACG8M1_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0420899.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            51753..52085
                     /locus_tag="ACG8M1_000146"
     CDS             51753..52085
                     /locus_tag="ACG8M1_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFQ0420900.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            52197..53405
                     /locus_tag="ACG8M1_000147"
     CDS             52197..53405
                     /locus_tag="ACG8M1_000147"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFQ0420901.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPSLKEEGEALLRFAELPSVPLKEESQVWTLLISQLGLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            53559..54014
                     /locus_tag="ACG8M1_000148"
     CDS             53559..54014
                     /locus_tag="ACG8M1_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420902.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            54376..54651
                     /locus_tag="ACG8M1_000149"
     CDS             54376..54651
                     /locus_tag="ACG8M1_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420903.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            54664..56736
                     /locus_tag="ACG8M1_000150"
     CDS             54664..56736
                     /locus_tag="ACG8M1_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFQ0420904.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRHADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            56904..58787
                     /locus_tag="ACG8M1_000151"
     CDS             56904..58787
                     /locus_tag="ACG8M1_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0420905.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSGDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            58799..59746
                     /locus_tag="ACG8M1_000152"
     CDS             58799..59746
                     /locus_tag="ACG8M1_000152"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFQ0420906.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKEVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            59766..60293
                     /locus_tag="ACG8M1_000153"
     CDS             59766..60293
                     /locus_tag="ACG8M1_000153"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFQ0420907.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEIDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(60357..61010)
                     /locus_tag="ACG8M1_000154"
     CDS             complement(60357..61010)
                     /locus_tag="ACG8M1_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFQ0420908.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            61142..61984
                     /locus_tag="ACG8M1_000155"
     CDS             61142..61984
                     /locus_tag="ACG8M1_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0420909.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEEILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            62142..63038
                     /locus_tag="ACG8M1_000156"
     CDS             62142..63038
                     /locus_tag="ACG8M1_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0420910.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            63041..63754
                     /locus_tag="ACG8M1_000157"
     CDS             63041..63754
                     /locus_tag="ACG8M1_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFQ0420911.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            63774..64292
                     /gene="msrA"
                     /locus_tag="ACG8M1_000158"
     CDS             63774..64292
                     /gene="msrA"
                     /locus_tag="ACG8M1_000158"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0420912.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            64289..64516
                     /locus_tag="ACG8M1_000159"
     CDS             64289..64516
                     /locus_tag="ACG8M1_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFQ0420913.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            64668..65219
                     /gene="lepB"
                     /locus_tag="ACG8M1_000160"
     CDS             64668..65219
                     /gene="lepB"
                     /locus_tag="ACG8M1_000160"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0420914.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(65302..65844)
                     /locus_tag="ACG8M1_000161"
     CDS             complement(65302..65844)
                     /locus_tag="ACG8M1_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFQ0420915.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRVIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(66081..66479)
                     /locus_tag="ACG8M1_000162"
     CDS             complement(66081..66479)
                     /locus_tag="ACG8M1_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0420916.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWVMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            66740..67600
                     /gene="ylqF"
                     /locus_tag="ACG8M1_000163"
     CDS             66740..67600
                     /gene="ylqF"
                     /locus_tag="ACG8M1_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFQ0420917.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            67593..68360
                     /locus_tag="ACG8M1_000164"
     CDS             67593..68360
                     /locus_tag="ACG8M1_000164"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFQ0420918.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            68416..69273
                     /gene="dprA"
                     /locus_tag="ACG8M1_000165"
     CDS             68416..69273
                     /gene="dprA"
                     /locus_tag="ACG8M1_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFQ0420919.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            69395..71473
                     /gene="topA"
                     /locus_tag="ACG8M1_000166"
     CDS             69395..71473
                     /gene="topA"
                     /locus_tag="ACG8M1_000166"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFQ0420920.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            71442..72818
                     /gene="trmFO"
                     /locus_tag="ACG8M1_000167"
     CDS             71442..72818
                     /gene="trmFO"
                     /locus_tag="ACG8M1_000167"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFQ0420921.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            73016..73921
                     /gene="xerC"
                     /locus_tag="ACG8M1_000168"
     CDS             73016..73921
                     /gene="xerC"
                     /locus_tag="ACG8M1_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFQ0420922.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            73958..74506
                     /gene="hslV"
                     /locus_tag="ACG8M1_000169"
     CDS             73958..74506
                     /gene="hslV"
                     /locus_tag="ACG8M1_000169"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFQ0420923.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            74520..75920
                     /gene="hslU"
                     /locus_tag="ACG8M1_000170"
     CDS             74520..75920
                     /gene="hslU"
                     /locus_tag="ACG8M1_000170"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFQ0420924.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            75938..76729
                     /gene="codY"
                     /locus_tag="ACG8M1_000171"
     CDS             75938..76729
                     /gene="codY"
                     /locus_tag="ACG8M1_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFQ0420925.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            76811..77686
                     /locus_tag="ACG8M1_000172"
     CDS             76811..77686
                     /locus_tag="ACG8M1_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFQ0420926.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVIRYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(77818..78456)
                     /gene="plsY"
                     /locus_tag="ACG8M1_000173"
     CDS             complement(77818..78456)
                     /gene="plsY"
                     /locus_tag="ACG8M1_000173"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFQ0420927.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            78583..79017
                     /locus_tag="ACG8M1_000174"
     CDS             78583..79017
                     /locus_tag="ACG8M1_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFQ0420928.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            79183..81228
                     /gene="parE"
                     /locus_tag="ACG8M1_000175"
     CDS             79183..81228
                     /gene="parE"
                     /locus_tag="ACG8M1_000175"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFQ0420929.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            81240..83690
                     /gene="parC"
                     /locus_tag="ACG8M1_000176"
     CDS             81240..83690
                     /gene="parC"
                     /locus_tag="ACG8M1_000176"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFQ0420930.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            83967..86198
                     /gene="pflB"
                     /locus_tag="ACG8M1_000177"
     CDS             83967..86198
                     /gene="pflB"
                     /locus_tag="ACG8M1_000177"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFQ0420931.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            86442..87203
                     /gene="pflA"
                     /locus_tag="ACG8M1_000178"
     CDS             86442..87203
                     /gene="pflA"
                     /locus_tag="ACG8M1_000178"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFQ0420932.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            87288..88214
                     /locus_tag="ACG8M1_000179"
     CDS             87288..88214
                     /locus_tag="ACG8M1_000179"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFQ0420933.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            88396..89289
                     /locus_tag="ACG8M1_000180"
     CDS             88396..89289
                     /locus_tag="ACG8M1_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFQ0420934.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            89423..89548
                     /locus_tag="ACG8M1_000181"
     CDS             89423..89548
                     /locus_tag="ACG8M1_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFQ0420935.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(89682..90314)
                     /locus_tag="ACG8M1_000182"
     CDS             complement(89682..90314)
                     /locus_tag="ACG8M1_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420936.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITVAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(90462..91004)
                     /locus_tag="ACG8M1_000183"
     CDS             complement(90462..91004)
                     /locus_tag="ACG8M1_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFQ0420937.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            91139..91528
                     /locus_tag="ACG8M1_000184"
     CDS             91139..91528
                     /locus_tag="ACG8M1_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420938.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            91532..92296
                     /locus_tag="ACG8M1_000185"
     CDS             91532..92296
                     /locus_tag="ACG8M1_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0420939.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            92425..93372
                     /locus_tag="ACG8M1_000186"
     CDS             92425..93372
                     /locus_tag="ACG8M1_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0420940.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            93502..94242
                     /locus_tag="ACG8M1_000187"
     CDS             93502..94242
                     /locus_tag="ACG8M1_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420941.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT        32175 a        16291 c        19841 g        26129 t
ORIGIN      
        1 caaatgacaa ctattttctg atttattaca aatgtttttt caaataaatt tgattaccaa
       61 gaaaaggtag tggtatattt actgagggat actttgaaaa acatatgata gaaacagtaa
      121 cagcattatg aaaaatcttt ttataaaaat ggaggaatcg atttgatgga agatcagtat
      181 gtacaagcaa tgacgatcgc aggatcagat agcgatggaa gcgcagggat gcaagcagat
      241 atgcatacat tctttacaag aaatgtttac ggtgtttctg tcatgaccgc atgtgttgca
      301 ggtaattctt acggaatcgg agcaagtgtg acattgccaa cagattttat cgacaaagaa
      361 tttgaactga ttgcgaagga ctttcaaata cgtgcagcta aaacaggtat gctagcagat
      421 tcaaagttga ttgagacagt tgtaaaaaat taccaaaaat atgattttgg accattagtc
      481 gtggatcccg taatcgtaac gaaacatgga aatcttttac tagaagaatc tgctttgcaa
      541 agcttgaaag aaaagcttgt ccctttggcc gaagtactga cacctaattt ttatgaagca
      601 gaaaagctga ctggacggac attagcagct gaagaagatt ttgtgcaagc agcaaaagaa
      661 ctgcaagata tgggtgcaaa aaacgttatg atcaaaggac atcatgctaa agatgcgcag
      721 caagaaacag tcaatgacta cgtattgctc gaatcaggaa aatcattttg gttaaatgca
      781 ccattttatc ctaccgaccg gatcaacgga actggcgatt cgctatctgc atgtattgca
      841 gctgagttag cgaaaggaaa aacagttgaa caagcgatcc gattggcaaa agactatgta
      901 aaccgtgcaa ttcgtgaaga aataaatgta gggcacaaat atggacccat caatcattgg
      961 gcagctggtg aattagagta aaagaaagag gtcgtgagcc tgccgtccag ctccgagtca
     1021 caaggaacaa gttcaaaaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga
     1081 ggagttggca ggagaacacc gtttgttcgg aagaagggac tgtgacaaga tttttgtcac
     1141 agtcccttta atcttagtat atttttctct acttgaataa aaaaattata ggattggaga
     1201 aaataatcga gaaatttgtt gcttgaataa tagccagtta gacatttcct tgactgtttc
     1261 agttgtcatg gatgaacaat gtgtctcatc ttctttgaac tgagtagcaa gttcttctaa
     1321 aaactcagga tcgtaaatga cagcacttgt ttcaaaattc aatcggtagc tacgaatatc
     1381 ttgatttgct gaacctacca tgcagatttc atcatccatt atcaatgttt ttgcatggag
     1441 gaagccgttc tcatagacaa ggatttgtac attttccttg atcagctgcc gagcataata
     1501 ttgtgttgct cgataaataa aaggatgatc cggtttgttg ggaatcatga ttttcacatc
     1561 tacaccagag gcagttgcga tttttaaagc agcaatgaca ctttcatcag gaacaaggta
     1621 aggtgtctgt atccaaacac gttttttagc agaagtaatc aatttgataa atgaaagctt
     1681 gatttgttcc ctttcgttat tcggtccgct tgaaacaagc tggatggatg tatcagcaag
     1741 cttagattca tctcgatctg cttttttaaa gaaataattc aaatgatagc cgaccttttt
     1801 ttcttcaggt accgagacgt tccagtctgt taagaagcga agctggagca aagaagaagc
     1861 ggcaccgaaa atccgtatat gcgtatcgcg ccaatagccg aatttttttg ttgtatttac
     1921 atattgattg gcaatattga aaccaccggt ataactaatc tttccatcga tcacaacgat
     1981 ttttcggtga tcatggtaat tcaatcggaa acgaagtaat gccttttgtg aggtaacaaa
     2041 tgtatggaca tgtccaccat ttttgattag acgattgaaa tcttttgctt ttgtaccatg
     2101 agagccaaat gcatcatata atattcgaac ttccacgcct tctgcggctt tttcttctaa
     2161 aacatgtaag acttgctggc cgatattatc tgtcacaaat gcgtaatatt cgatatggat
     2221 cgaatgtttg gcttttttta gatcttgaag cagtgaatcc aatttctctt gtccgtctgt
     2281 gagaagagtg acagaattca ttcttgtcag cggcatacga tttaatgaag agaagaagtc
     2341 gacaaattgc tgtttgtctt tatcgcccat gtcaggatcg taatgttcaa tggtatctcc
     2401 tctaaaagac tgaaagtttt ctaattcttt caagtcactt tgtcggagat agaatttttt
     2461 cttatccgtt aatccacgtc cgaaaaataa atataataca aagcccaccc caggaagggc
     2521 aaacaatact aagagccatg cccaaatggc tgctacatct cggggtttga tcaaaatagc
     2581 caccaaagca ataagtgcat ttaatagata aagggcggtt ataatactag ataccacaaa
     2641 aatgttcctc cttacataca ataacattag tatagcatga tagaagaaag aagcctacca
     2701 aggtgaatat acttttcact cctttcatga aaatgtaggt aaatcgggct aaagtagttg
     2761 ctttttgtag gttaataagg taggatatta gtacagttga atatctcctt aggggagtaa
     2821 ccggcaacgt ttgttgcgat aatatcaaca gtaagttaac caaatggttt tctggtattg
     2881 tatgaaatgg tgagacctaa gacaaatgcg tatttgtctt aggtctcttt ttttttcaga
     2941 caggactagg gccaagatca aaaaatgggg gatgaaattt ggaaaacaag gaacaagcac
     3001 aacaagcggt ctataaagaa acgatcgact cgttgatgca gcaaacgcag agctcaaccg
     3061 atggattgag caccacgcaa gcgaaggaaa aattagaaag agatggcttg aaccagctaa
     3121 aagaaaagcc gaagaagcca acttggaaat tgttcttaga aactttcaaa gatgcaatgg
     3181 ttatcgtatt gctgattgtc gcactgattc agatggtcat gggtgactac atcgaattct
     3241 tagttatttt tgcagtattg atgttgaatt ctataatcag tgttgtccaa acaaaaaaag
     3301 cagaaggttc tttagaagcg ttgaaaaacc tttcagcgcc cgatgctcga gtgattcgtg
     3361 atggtaagga aaaaacgatt ccggcaaacg aacttgtggt aggagatatc gtgttgttag
     3421 acgcaggcga ttatgtacct gctgatggac gtttactaga tgcgggatca ttaaaagtag
     3481 atgaaggtat gctgacagga gagtcgactt ctgcagaaaa agaagtaacg gatatcacaa
     3541 gtacggtacc aatcggagat cgtacaaata tggtattcag tggaacgatc gtaacttacg
     3601 gacgcggtaa attcttagtg acttcaactg ggaataatac ggagatcgga caagttgctg
     3661 gccttttgga atcaacaact gagcaagtca ctccgttaca acgaggtctg gataaattca
     3721 gtaaaaaact aagtctggct attttggcat tgtctttatt gattttaggt atccaactgt
     3781 ttcgtattta tcttggagaa ggtacaggag atatgactgc agatatcgtc agcgcagtga
     3841 tgtttgccgt agccgtagcc gtagctgcta ttccagaagc attacagtct atcgtaacaa
     3901 tcgtgttatc tttgggaacg aataaaatgg caaaacgtca tgccattatt cggaagcttc
     3961 cagcagttga aacacttggt tcgacaagta tcatctgtac agataagact ggtacattga
     4021 cacaaaacaa aatgacagtt gttgactact ttttaggtaa tggcgatact ggggatttca
     4081 caaatgaccc ttcaaaatgg acagctgacg aacgtcgctt gatcgaaatc agtgttttag
     4141 cgaatgatgc atcgatcagt gaagacggta ctaaattggg cgaccctacg gaagtagcgt
     4201 ttatcgactt tagtgaaaaa ttaaaccagc cttatcagga aatccgaaac aactacccaa
     4261 gacaagcaga acttcctttc gattctgatc gaaaattaat gtctactgga cacacgatcg
     4321 ataacgaaaa ttacttgttt gtcaaaggcg gaccagatat cgtcttccaa cgcagtaaaa
     4381 aagtattgct aaatggtgaa gtcgttccga tgacggatga attgatgaaa aaattccaag
     4441 agcaaaatga agctttttca acacgcgcat tacgtgtact agcttttgct taccgtccac
     4501 ttgataattt tgatttatca tttgaagatg aagacgattt gatccttgtt ggtttgcttg
     4561 ctatgatcga tcctccacgt gctgaagtga ctcaggcggt aacagaagca agaagtgcag
     4621 gaatcaaaac aatcatgatt actggtgacc acaaaacaac agctgttgct atcgcaaaac
     4681 aaatcgggat ttttgaagaa ggaaacctgg ctttgaccgg gacggaacta gatgaattga
     4741 cagaagatca actaaacgaa gttttagaaa aagtcactgt ttatgcacgt gtttcacctg
     4801 agaataaaat tcgtatcgtt cgtgcttggc aaaataaagg tcatatctca gctatgacag
     4861 gtgatggtgt aaatgacgca ccagcattga aacaagcaga catcggaatt gctatgggaa
     4921 cgggtacaga tgtggcaaaa gatgcagcag cgatggtatt gacggatgat aactttgctt
     4981 ctattgtcag cgcagtagaa gtaggacgta atgtgtttga taatatcaag aaagctattt
     5041 cttatctatt tgcaggaaat ttaggtgcga tcattgcgat catctttgcc ttagttgctg
     5101 actggtccaa tccatttaca gcattacaac tgttgttcat caatttagtc aatgattcac
     5161 tgccagcaat tgcattaggt acagaaaaag ctgaacctgc tacgatgaac cgcccgccaa
     5221 gagatccaaa ttcaggaatc tttacggaca aaacattgat ttctgtaacg tatcgtggtg
     5281 tgctgattgg gattgctgtt atctttgctc aatggcttgg catgcagcat tcacctgaat
     5341 tcggtgtagc catgtcattt tcaacattga tttggtgtcg gacattgcaa acattcccag
     5401 cacgttcaaa cacacaaaca gctatccaag cagggttctt ctctaacaga agtgtcttac
     5461 tagctgtagt tgtatgtagc gcgctttact gcttaacaat gatcccagga ctgaaagaag
     5521 tcttctctat cccatcagca tttggattga cagaagtctt tacatgtatg ggaatcgcac
     5581 ttgtgacaat tgttttgatg gaaatcacta aattgatcat tgtacgagta caaggaaata
     5641 aataaaacga atcaacgagg ttgtgagcct gccgtttaat tctgagtcac aaggtgcaat
     5701 ttcaacaaac agcttctcat gtttgttgaa tattgtgact tgtgaccgaa gagttggcag
     5761 gagaacaccg tttaaggaag aagttgtaaa atcagcattt tgagctaata ctgagggtca
     5821 tctgattgga cactgtttat tcggaaagag ggactttgac acgactttgg tcacagtccc
     5881 tttttttatt tatgatagac ggaaagccaa tcattttatt attcatcaaa agagatagaa
     5941 tagataaaag aggagaataa tttattccga aaagtgaaaa catataacaa aaaattagag
     6001 gaaatcaaat gaatgaaaaa gaatgggatg aatttgctga agaatattat gaaatccagc
     6061 aagaatcgca agtaactatt gctgaagatg taaaaaatta tctgaaaacg gagaaagtcc
     6121 tgcctgctga aacagcagca gacgttgctg gaggatctgg cagatttctt tccttagcaa
     6181 aagaaattaa tcgctatgat ttgatcgatt tttcttcagg aatgctagaa aatgcaaaaa
     6241 aagaagcaga aaaaaatgag ttgccaaatg tttcctttat caaacagtcg ttagaagaat
     6301 ttatccaatc aaatgagaca tatgaaatgg tttttacagc agcaaatcca gcattggtac
     6361 atcttattca attagaaaaa ttgatgaaaa agtcaagcaa atggtgcgtg ataatcaggg
     6421 tagtggaatc aatcgatgat gttttttatc ctatcgaaaa gcaactagga atgatagaag
     6481 aagatcctaa tacatcgcca gttgtaatgg atcaatttga aacatactta attgatgaag
     6541 gattcaaagt gaagaaaaaa gattttactt attttacaca ggaatcaatt actgaagaat
     6601 tgatgaagct atactatgac gcgtacgcaa aagatcctgt tgtgaccagg tacattcgca
     6661 aactattcag tgaaaaacga gaaatcctta gtacgactaa gctgacctat agactgctcc
     6721 tttggtccgc agataaaaaa agaacctttc acgactcgtg aagggttctt tttatgattt
     6781 tattatattt tgtagtaacg aatatcattt tcgatctttg taatcgaaaa aggtacatct
     6841 gaagtatatt ctgcacattc tccgtgttca ggaagcgtct cactgaaaat cgtttcatat
     6901 tcgtcaacag tgatccgtgt tcgagaatct agcatctctt gatgagattg tgcgaagaga
     6961 tattcttgat agttttcttc cagataacct gtaaaaaatt cacttactgc accagaaccg
     7021 tagctgaata gaccgatgcg atctcctggc tgtagtgatt tcgaattttc cagtagagaa
     7081 gttagcccca ggtataatga accagtgtaa agattaccga ttcgtcggct gtaacggatg
     7141 ctttcttcat agcgagccat aagacgttcc tgattttctt cgtctgtttg gtctaatacg
     7201 ctttgcaatg ccttttttcc catcttagta tacggaatat ggaaagcaat cgcctgataa
     7261 tcttcgagtc ctcgacccga caattcttta tgtcgattcc aaactttttg gaatgattcg
     7321 atatacgtag aattagataa aggaccatca acaacaggaa attcgctata atctggacgc
     7381 cagaaatcat agatatcttc tgtcagaaat acgctgtcgt cttcaatcga taaaatacgc
     7441 gggttttgag tgatcatcat cgcaacagca ccgacacctt gcgtcacttc accaccgctt
     7501 gccaagccgt aacgagcaat atcacttgct atgactagta cttttcgttc tggatgattt
     7561 ttgacatatt ctttcgccat gtgcaaagct gcggtgccac cgtagcaagc ctcttttact
     7621 tcaaaagaac gagcaaaaga ttggattttc agtaaatggt ggataattac cgcactcgct
     7681 tttgaatgat caatcccgga ttctgttccg acgatgacca tgtcgattag ctcacggtct
     7741 ttttctgtta cgattttgct ggcagcattt gctcctagtg taatgatgtc ttcatttgca
     7801 cgattgactg ccatttggtc ttgaccaatc cctatatggt attttgcagg atcatcccca
     7861 cggctttctg ccaactctgt catatctaaa tataaattag gaataaaaaa ggaaagacga
     7921 tcaatcccta ttttcatttc aacacctctt tacttatgat aaaaaactta ctttactaag
     7981 gtatcataaa aagattaaaa gaaatataaa aaagagaata tttaaggatt gttaaaattt
     8041 aatcttagaa aaaaacaact ggaacaagag ctatttgttt ttacagcaaa gaatggtata
     8101 tttttgtagg aggtggctta cttgaaagaa gtcgttatga tagatgctgc aagaacgccg
     8161 ataggaaagt atcgcggaag tttaagtcca tttactgcag ttgaattagg cacacttgtg
     8221 actaaaggat tattagataa aacaaaactg aaaaaagata aaatcgatca agtaatattc
     8281 ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca gacagattgc tttgaacagc
     8341 ggtctccctg tagatgtccc agcaatgacg atcaatgaag tttgcggatc tggtatgaaa
     8401 gcagtgatct tagcacgcca gctgatccaa ttaggtgaag cagaacttgt gatagccggc
     8461 ggaacagaga gtatgtctca agcacctatg ctgaaaccgt atcagtcaga aacaaatgaa
     8521 tatggtgaac caatttccag tatggtcaac gacggattga ctgacgcatt ttcaaatgca
     8581 catatgggat taaccgcaga gaaggttgca acacaatttt ctgtgagcag agaagaacag
     8641 gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg ctgtcgaagc cggtgtattt
     8701 tctgaggaga tcatcccagt caagatttct gatgaagacg tgttatctga ggatgaagca
     8761 gttcgtggaa atagtacatt ggaaaaactg ggcacgttac gtacagtatt ctcagaagaa
     8821 ggaactgtaa cagcaggaaa tgcttcgcca ttgaatgacg gtgcctctgt ggtgatcctt
     8881 gcatccaaag aatacgcaga aaataataat ctgccttatt tagcaaccat caaagaagta
     8941 gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc caatcaaagc cattcaaaaa
     9001 ttgacagata gatcaggaat gaatttatca acaatcgatc tttttgagat caatgaagca
     9061 tttgcagctt cttctatcgt agttagccaa gaactgcagt tagatgaaga aaaggtcaat
     9121 atatatggag gagcaatcgc attaggccat ccaattggtg caagcggtgc acgtatcttg
     9181 actacattag cttacggatt gcttcgtgaa cagaagagat acggtattgc ttcattatgt
     9241 attggtggag gtttaggctt ggcagtcttg ttagaagcga atatggagca aacacataag
     9301 gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg aacggcgcag tcaattaata
     9361 gaaaaaaatg tattgacaca agaaactgcg ttgatttttc aggaacaaac actttctgaa
     9421 gagctctccg atcacatgat cgaaaaccaa gtgagtgaag tggaaatccc aatgggcatc
     9481 gcgcagaatt ttcaaatcaa tggtaagaaa aaatggattc cgatggcaac agaggaacca
     9541 tctgtcattg cagctgcaag taatggtgca aaaatctgtg gaaatatctg cgcagaaaca
     9601 cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa aatcggagta tcaagcagtg
     9661 atcaatgcag ttaatcatcg aaaagaagag ctgattcttt gtgcaaatga aagttatcct
     9721 tcaatcgtga aacgcggggg cggtgttcaa gatatctcta ctcgggaatt catggggagt
     9781 ttccatgcat acttatctat tgatttttta gtggatgtaa aagatgcaat gggcgctaac
     9841 atgatcaact cgattcttga gagtgtggca aacaagttac gggagtggtt ccctgaagaa
     9901 gagattctat tcagtatttt aagtaatttt gctacagaat cattggcttc tgcctgttgt
     9961 gaaatcccat tcgaacgctt agggagaaac aaagaaatcg gtgaacaaat tgccaaaaaa
    10021 atccaacagg caggggaata tgcgaagctt gacccttacc gtgcagcaac gcacaacaaa
    10081 gggatcatga atggtataga agctgtagtg gcagctacag gaaatgatac acgtgcggtt
    10141 agcgcttcga ttcacgccta cgcggcaaga aatggattat accaaggatt aacagactgg
    10201 cagatcaaag gggataaact agttggaaaa ctaacggtgc ctttggctgt tgccacagta
    10261 ggcggagctt ccaatatcct gccaaaagca aaagcatctt tagctatgtt agatattgat
    10321 tcagccaagg aactagcaca agtaattgct gcagtagggt tagctcaaaa cctggctgct
    10381 ttgcgtgcat tagttacaga aggaatccaa aaaggccaca tgggacttca agctcgttca
    10441 ttagcgatct caattggggc tattggtgag gaaatcgagc aagttgcgaa aaaattacgt
    10501 gaagcagaaa agatgaacca gcagacagct atacaaatat tggaaaaaat ccgggaaaaa
    10561 taaaaaagca atatctttag aagaataaag caagatttac agttatttta tttactgcaa
    10621 atcttgcttt tttctctatc agaaaatatg tttattatta gaatttttta tagttaaggt
    10681 taggcatctt aagaaatcag gcaactccaa gatatcttca ggtagaagag aagtcgccta
    10741 acattgtagg atcataggtg atttgttgga caggtcaagc tgatatttga gcctgatgtt
    10801 agaaggaatt tctttttact tgctgtagaa attattatat gactaaaaag gctgggattt
    10861 taaatcccag ccttttatga caaatagaat ttttatcgat cagtaatcgc tgtcgctgca
    10921 aattgttcga tcaaaggaat caaagtcaat ttgactttgt atttccgttc gagtgctttt
    10981 tcgataacga actcattttc agtagtcata gaaatagttg ctaatttacg aggttcatca
    11041 gcattttttt cattaataac tacttcatgt tcattttgtt ctgtgtaaaa tttaggatac
    11101 tcagcaacgg cttttgaaaa atcagcaaaa cttaaagcgg cattcgtatc agttgagcgt
    11161 gtattttcag ttgtgtccgc ttttggtttt tccgtttttt cttctggcac actgactgtt
    11221 tcttctgtaa ctggtgtcgc aacagcttgc gcagttggtt catcgttttt caatcgttga
    11281 tcattccagt aagacacgat ttcaataaga agattgtcac ggaatcgttc gaaaatcccg
    11341 ttttctcctg aacgaattct ctttaataca gtattgaagt tgtcatcgat tggcacgttg
    11401 atccgtgtat cttcatttgt tttcccagct aatccgatcg ttaagatttg acggtttttg
    11461 ggatcaagca tgacttgtaa cggcaaacca tagcgtcgca agctctcttc ttctagagaa
    11521 cggaataatt gtcctcttac accatccaat gaaggacgga attgatttaa taatttttgt
    11581 ttctgttttt tcttcatatg ttctctcctt cgctcatacc ctttcgatta taagaaaaaa
    11641 acagccaaat gaaaaggagt aatgcaaaaa aacttgcgta tacgcaaatt acaacagaaa
    11701 aatttgcgta ttttcccgtt ttttgaaaga aaaataaaaa atggaacgga ttatgtatat
    11761 atacataatc cgttccattc tttctatttt ttcggtatca aggcaaaaac aggtagttca
    11821 ggtgaataaa tgacttcatg ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt
    11881 tttttcagtt cttcgatgat ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt
    11941 ttctctgcat cgatcaaaaa gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag
    12001 agagaattca agcgttcgat tggatccata aaatcacctt tcgacttaaa attgggtagt
    12061 atctgggtct tttgctttgc cgactacacc atctaactga tcgatttgtt tcatttcttc
    12121 ttctgttaat tcaaaatcaa ataattcagt attttctttg attctgcttg gtgtcactga
    12181 cttaggaaga ggaaggaatt cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt
    12241 cttgtcatgt gcttcagcga tttgtttcat ttcaggcaca tcgaagattt taccagtgcc
    12301 taatggacta tatgcttcga ggatcatatc atgttttttt gcatactcaa ctacagttgg
    12361 ctgtaattcg cctggtgcaa ggaaaacttg attgaccatc ggcataattt ttgctgtttt
    12421 tgctagtgta tctagatggt ggggtaagaa attgctcaca ccgattgctt tgattttacc
    12481 tgcttcatac agttcttcaa atgctcgcca tgtatctgca tttgcttgtt cccaattatc
    12541 acgaaaagca acagggtttg gccagtggat caaaaacaga tctaaataat ctgtttggag
    12601 cttcttcaat gattcttcaa aagaagacat cacaagttca tagctgtggt ttgcattcca
    12661 taattttgtt gtcaagaata tctcttctct aggaattcca ctttccttaa tcgcttggcc
    12721 gacactttct tcattcttgt atccttgggc agtatcgata tggcgataac ctgcagccag
    12781 cgcttcttta acagaggaaa cagcgacatc cccatcaggt gtttgccatg tgccgaatcc
    12841 tactaccggg atttcgtaac catttaatag acgataagtg cttgttaatg aattcatact
    12901 ttcagctcct tttttattcg ttcaactata agtgtagcgc atttttcgaa aaaaagaatc
    12961 cattttgttt ctactcttga aatttttgtt taaaagaaaa tgattttgat tctggtattt
    13021 ttgatttttt ttccgtaaac taagacagaa gggaatgaga aaatggatat ctatttaaaa
    13081 aaagcaattc tgcatattat tgacagagaa actggttctc cagtcttttc acaaaaagag
    13141 ctggatctga caaaagaata tattcgtgat tttcttcaaa agaagatcca aaaaatctct
    13201 tctgctcaaa caaaaactgg acaactagca gaagaaagca tgatcgttga atcacttaaa
    13261 atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc
    13321 taccaagaaa gtgaagaagc acctagtgca gatgtatttg ttgttttgta tgaattagat
    13381 acagtgatgt acttatcttt attgaaagtc aattatcgtg aggcttacac tcactttgtt
    13441 gaagcagacg aagcagggat cgacaaccgc ttgattttga atcgagcaat tctaggggcg
    13501 aaaacacaaa aagcagatga agcattcgct gtgaatttga ctgattggac ctacgaatta
    13561 attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt atttttctgg aagagtgatc
    13621 gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag tgatccaaaa agtagccaag
    13681 catcttggaa aaaaatttga gacagaagaa tttgatatca tggctgattt gaaagaagct
    13741 gtctatgata cgatagaaga aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc
    13801 ttcaaggaaa acatcacggc aaaaatggct tttaaagaag aagtacaaga gcaaggattt
    13861 gtcccagaag cacctcctgt aaaagaagta caagaaattt ctgagaaaaa atttggaaaa
    13921 caaaaattca agctatcaaa cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac
    13981 ccagatttga ttgaatttgt gaataatccg gatggtacga tatccgtgat gatcaaaaat
    14041 gtggatgaag tattgaatcg tttataaaaa tgactagaac attaggtgtt caagtaccag
    14101 tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa agacgaatat aacaaaaaaa
    14161 gagcgtgaga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg
    14221 gaagcagaag caactccttc ttatttcttg gagttaaacg cttctgtccc agcctctttt
    14281 tatctaataa aattttaaga ccatttacta attatcgatt ttttctgccg catttttagg
    14341 cacttcagaa gcctttattt cttcccagct taatacacct ttacgaggat tgactttgag
    14401 tttaagatac gcattcatct ttaatggatg ttctctttct tcgcgaagcg tcacctgttt
    14461 tttttcacca tctttattat aagccgcttg cttgtaggta taagtcgtga atttctctcc
    14521 gttatctgct tgggtagctg acatttcgcc attcgtcgtg atttttgtat aataagcttc
    14581 gccgccgtaa aaataatgat aagctgcaaa acttccgccg agaaatatgc ctaaaacgac
    14641 aagtacgcca attaattttt tcatgtactt cacctctttc cttattatta acgaaataga
    14701 agatttcgtc tattgaaagt tgttggcaac agctgaattt taaacttttc ctcattttgt
    14761 tcttattgct tcaaaagaaa gttaaggact atcttgaagt ttttctcaaa aaacacattt
    14821 ttttatttat aaaaggtact tttttcgcgt ataagacaag cgagtgctct tagttgactt
    14881 tgaccaatat tgacgtataa taagcttagt tcgaatctta caaaaagtaa gtcggacgta
    14941 ttctttttga tttagtcaaa aaaagactat aataaaaagg tgagagctga aatttttcag
    15001 tgatctatat tatttaggag gtttgtaaat tatggcaaaa gaacattatg acagaagtaa
    15061 accacacgtt aacattggta cgattggaca cgttgaccat gggaaaacta ctttaactgc
    15121 tgcgatcact acagtattag gcaaaaaagg cctagcaaat cctcaagact atgctagtat
    15181 tgatgcagct ccagaagaac gtgaacgtgg gattacgatc aataccgcac acgtagaata
    15241 tgaaacagaa aaacgccact acgcgcatat tgatgcacca ggacacgcgg actatgtgaa
    15301 aaacatgatt acaggggcag cacaaatgga tggtgcaatc ttagttgttt ctgcaactga
    15361 cggtccgatg cctcaaacac gtgaacacat tttattgtca cgccaagttg gtgtaaaata
    15421 cctgattgtt ttcttgaaca aagttgattt agtcgatgat gaagaattga tcgatttggt
    15481 agaaatggaa gttcgcgagt tattgagcga atatggtttc ccaggcgatg acactcctgt
    15541 gatcaaaggt tccgcattaa aagcattgca aggcgatcca gatgctgaag ctgctattat
    15601 ggaattgatg gatacagtag atgaatatat cccaacacca gaacgtgata cagataaacc
    15661 attactattg ccagtggaag acgtcttctc aattacaggt cgaggaactg ttgcctcagg
    15721 tcgtattgat cgtggtgctg ttcgtgtcgg tgatgaggta gagatcgtag ggatcaaacc
    15781 tgaaacacaa aaagcagttg taacaggtgt agaaatgttc cgtaaaacgt tagattacgg
    15841 ggaagctggg gataacgtag gcgtgttgtt acgggggatc caacgtgacg atatcgaacg
    15901 tggacaagtg cttgctaaac caggttccat tactccacat acaaaattca aagcagaagt
    15961 gtacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcaaca actatcgtcc
    16021 acaattctac ttccgcacaa ctgatgttac aggaacaatc acattgccag aagatacaga
    16081 aatggtcatg cctggtgaca acgtgacgat tgatgttgac ttgatccatc caatcgctgt
    16141 tgaaaacgga acgacattct caattcgtga aggcggacgg acagtgggtt caggtatcgt
    16201 tacagagatc gaagcataag aaacgcgact cgaatatttt ggtaatgaaa aatgtttaaa
    16261 ataaaagagc ggtccaaaca ggatttctgt ttggaccgct ctttgttctt caattgtata
    16321 agaagagatt gtagaagcat gaactttcgt tttacttcag tctcttttat tcatcatgag
    16381 agtgttcatc tatcggtatg cagtttttaa tactttcttc gtatccattt tttcaaacca
    16441 cttattctac cttgtgtctg ctcaactggc gcattatcaa taatcagcaa agcaatcata
    16501 acatatgcaa tccaactatc tctagaatat agagtataac gtgagaccca gtttgtagcg
    16561 tacttgcttt tatattctct taatccatgg aaagaataaa aatgagaacc aaactcgtaa
    16621 accaagtatg caatcctttc ctgtaaaaaa ctctttctgg aagttccgac atttgaaaga
    16681 ggggccatcc ctaaattgaa ccattggata tgttcttctt tcatataggc aaacaaatgc
    16741 aagaacaaga aatccatact gccagaaggt gcttttttag gatcatatcg catcagatca
    16801 atcgttccta ctttattgtt cgtgtaagta ggcatgatcg ttgcaaaagc gacaatttct
    16861 tcttgggtat ttttgacaac tgcaataggc gctctttgta gataatcttc agagaaaaag
    16921 cctaaagaaa accctttttc ctttcgtgaa cccaaccaat tatcagagat atttttgaaa
    16981 gtactcattt gctcagtaga aaatggtggt tgtaagacat caaatgtaaa tccttctcgt
    17041 tcgatccgat tcaagacagc acgagtgccc ttcatttttt tccctgaagt tgtaaaacta
    17101 ttcaggtcta cataagcttc ttcccccatc ttaatgaaat cgtagccgaa ttcatgcaaa
    17161 atcataacaa tctcttcgct tgtttcgtag aaaactggta aatagcatag tcgatctgtt
    17221 tcttcgataa aagcttcgat tgcttctgga aaatcttctt tcttaccaga aggatcaccc
    17281 attacaatac atttattatt gaagcaagcg aattggagaa gaacagttgg ttcaccgtct
    17341 ttttcatagg caaacatccg cttatctttt aagaagatca attgactatc ggagtttcct
    17401 ccataagttg taaggatctt cagggccttt tcttcattaa aggcttcgcc aatctgtttc
    17461 ttttctcctt gaaggaaatg aacaaataga acgatcatga aactaacagc gatgatggcc
    17521 aacaatcccg aaaaccaaat cttttcagaa ggaaataaga aaaaggaaat aaaatggtga
    17581 cgccgatgag ggaaatccgg cagattgtat accccaataa cgatgtaaag caaggacagt
    17641 gcaccaataa tgattccatc gatcgtacgc cactcccatg aatagatcaa ttgttcccga
    17701 aataattcgt ttttagaagc aagaatgatc agaagcagaa tagacaagaa aaccaccggt
    17761 gtgaaactaa aatcacttaa taaaacataa agtaaagcta gaacaatcaa gaagattgta
    17821 ggcaaatatg ctcgtttcac acgtgctgcg atccctctgc ccataatgat taaaagaaat
    17881 cccaatagta tactaggaaa ttggataata aaatgaaatt tcaatgggtt caaactatga
    17941 agccagcgaa actctgtaaa agcttgcggg atagtggcag aaagtactag catgattcca
    18001 gaaaagtata ataagacaac cacgatttta tgcgcaattt ctgttgctaa ttgtttaggg
    18061 ataccagaat aacgctgatc aaaagtggaa ccgatatttt tgaagaaaaa gacgattcca
    18121 atcaaaaacg gaatgatgta gtagaacagg cgatagagca agatccacac aacgactatt
    18181 tctcttggca caccaatagc ggacaacccg ataatcatca ttacatcgaa actcccaatt
    18241 tctcctggaa tcatagacac gattcctatc actgaagcag caatgaataa cggaattgtt
    18301 tgccacagat caatccggat ttccattaaa taaccaacag aaaggaaact aaacaggaca
    18361 ccggtccatt ccaacaatga aactagcaat agctgtcctt gagttttaag tgaggtacca
    18421 ccaaggaatc ctttcttttt gaaagtagta aataaaaaga cgacaggaaa atatagaccg
    18481 ccgccgatca accatatcca atattgcttc aaaaaaggag caactggcgt gaagactaca
    18541 agtaaaaaag aaagcagact gtaaatagaa agtccagcca tcaaaaacaa gaaaactttc
    18601 gataatgctt ggatcacgtt tctgctctct ttcttttgtc catatagttc agagcgaagc
    18661 cccacactaa caaacccgcc gaaaccggca atattgttga ttgtattgat cagccagctt
    18721 gtctcaaaca agtaacgagg attctgcttt tgttcaagca tccgattcaa aataatatca
    18781 taaccaatca taggtaacac agagacaaga ccaatcaaca gcataagtcc gcttttccat
    18841 acaggtatag tggcaaacgt ttctcctaat tgctggatag atagagtttt accgatggac
    18901 atcaattcac cgacaataat gacaatgaca gaaatcaaaa agattgtttt gaacagtcct
    18961 aggtggtttt tcagccattg tatggtattt tttaacaaat aaatcacctt ctattcctaa
    19021 tagttatgtt tcagaaagaa attgaagaac ttctcgattg aagcgttcag gatcttttct
    19081 agctaattca tgtccttgtt ctttcacaag cacaaaggaa gcttttggta tagttttagc
    19141 tatatacaaa gaatgtttta gcttgattac atcttttttt cccacgatga tcaaagtggg
    19201 ggagttgatt ttttttaaat cattttctgt aagcccgatg tcatgcagca aaagtttgat
    19261 aactaaaaga tttttgcgaa gacttgggcg aaataaagag agtaaccata cccatgcata
    19321 atgaatatta ctgatgactc tggcagaaaa acgaacgcct ttaacaagcg tgtttccaga
    19381 atttaaaatc aatcgatgaa cttttttagg gaagctgctg gcaaatacca gtgctagatt
    19441 tgctccatca ctaaatccaa gaaaatctgc ctgatcgatt ttttccagca acatgatcgt
    19501 attcagatcc tcggccatta actgaaaatt caacatagat gcttcgtttg tcgaacgacc
    19561 atgtcctcgg ctatctacta gatacacggt atagtagcgt tcgagtacag ggacctgttc
    19621 tgaaaaaaag cggccgctgc cgtcattgcc atgcagtaaa aagagaggga agccttgacc
    19681 gctcttttca tagtaaattt cgctcccatc tggcattttt gcatatttct tttctttttt
    19741 cacataatca cctactgtgt aaagtataac gattatatca gtcattgggc aattgttttt
    19801 actgaaaaac aacgatcatt ttcgtaagat gacaaaaaat acaggaaaat tcattttttc
    19861 ttaaggcgta cacagaaatc aaggaagaaa tagccaagaa gataaagaaa tagtaagata
    19921 aaaaaagatg tcaaaataac taggtgatga aatgaagcga aaacgattat ctattatccg
    19981 tattcttttt tacatgatca ttctgacggt tattggtgcg gtgttgtttt taggaggaag
    20041 aacttatcgt tcggtaaaac gagtggaaag ctatcaaata gaaataacaa cagctgcaaa
    20101 aaattatcat atggaaaact acgagaattt gatcaaggcg ataatattga ccgaatcaaa
    20161 aggaaaaggg acagatctca tgcggagctc ggaaagtctg catggagaag ctgagatcat
    20221 tgataatcca gctgacagta ttgatcaagg tgtcaaatat ttggcggaaa tgatagtaga
    20281 agcaaagaaa caaggatgcg atttatggac agctgtccaa gcatataatt ttgggaaaga
    20341 ttatattgcc tatgtaaaaa atcatggcgg agaaaacaca gtagaattag cagaagcgta
    20401 ttctaaagat gtgctgagcc cacttttagg aaatgaggaa gggaaacaat accgatattg
    20461 gcggatccag tccttgcttt acaatggcgg ctatctctat cataatggag gtaacatgtt
    20521 ttatcctgat attgtcaaaa tgaatgaaaa aataatagag acctatgaaa aagtttttaa
    20581 gtaaaatagc aggaaatgtt caatcatgaa taaaattaaa tgaaagaagg agtgcgcaaa
    20641 tagtggaaaa aaggcaaaaa atggaaaatc aaaaagtggg gtacacaacc aaagactgga
    20701 tgttacggtt tgtgaaggga atgtttatcg gttcaggatt tatcttgcca ggagtcagcg
    20761 gtggtgcatt agcagctgtc tttggcatgt atgagcggct gatttctttt ttagcccacc
    20821 ttacaaaaaa tttcaaagaa aatgttttgt tttttctgcc tgttggtcta ggcggagtga
    20881 caggcatctt tctactttct tttttagtca gttttttatt aggtgcgtat gaaacaacga
    20941 tattatggtt ttttgtcgga tgtatcgctg gaactgttcc tgcgttatgg aaagaagcag
    21001 ggaaaaaagg aagagatact tctgatgtga tcatcatggt tgttactttt gttctggctt
    21061 atttgttttt attatacggc gctcaattat ttgacgggca agtcgatcag aattttggaa
    21121 catggctgat tgccggcgga ttgattggtt tgggtatgat cgtcccagga ttgagccctt
    21181 ctaatttttt ggtgtatatg ggattgtata aagcgatggc tgacggattt aaagaagtac
    21241 gacttgaagt gattgtgccg atcggaattg gtgggattct ttgtgttctt ggattgtcaa
    21301 aaatcatgga ttacattttc tcaaaggcat atagcaagct attccatttc attttaggtg
    21361 tagtttttgc ttcaacgatt atgatcattc ctaccgatta cgcgggattg ggagttgctg
    21421 gggtactagc ttgtcctgtt ctttttatag ccggtacagc actaggttgg tggatgagcc
    21481 gtttggagga acaatataag taaagataga ttgataataa aaacagcaca cgggtgattc
    21541 aaacaaaaag gttggcatct tttttgtaaa atcattcgtg tgtttttcta taaattttat
    21601 aaaaacaagt tgtttttaat cttggaacac gctagactta aacacgtgat tatttttgaa
    21661 agttggcgga aaatggagaa aaagaaaatg aatggactta cacagcaaga ggtagttcag
    21721 aaaatggctt ctggccagca aaatgactac caggaagatg catcaaaaag tacaaaacaa
    21781 atattcagcg ataatatatt gacgttattc aattttctga actttggtat tgggatttgt
    21841 ctgttatttg taggtgcgta ttccaacatg gcgtatttag caattattgt cgtcaatatc
    21901 gttattggaa tttatcaaga aatacatgca agaaatcttg tacggaaatt atcgattgtt
    21961 tcccaatcag aagtactagt gatccgggac ggtaaagaac aatcgatttc tactaaagag
    22021 ctggtattag gagatttggt aaaaatcgga gcaggagaac agataccagc cgatttacag
    22081 gttatatctg gacgggcaga agcaaatgaa gctcttttga caggcgaatc tgatttgatt
    22141 gtcaaagaaa ctggagctga attgctttct ggaagctttt tgacaagcgg ttctgtcatg
    22201 gctgaagtta tccgagtagg tgcagataat tatgctgtcc gcttgactag cgaggcaaag
    22261 actcacaaag ctattcgttc tgaacttgta gattcgattc gcaaagtatc caaattcact
    22321 agtttcgtga ttattccttt ggggatcata ctatttttgg aagcactgtt catccgcgat
    22381 gcttctatca aaatttctgt tattgcatct gcagcagctt tgttaggcat gcttccaaag
    22441 ggtttggtat tgctaataag tattgcatta acgacagggg taaccaaact ggcaaaaaaa
    22501 cgaatccttg ttcaagacat gtattcaatt gaaacgctgg cccatgtcga tacattatgc
    22561 ttggataaaa cagggaccat tactgaagga aaaatgagta tccagcgggt agaagcacta
    22621 catccgctgt acgagaaagc catcccagaa attatgggga cgtatctggc agaaagcagt
    22681 gataacaaca tcactatgcg ggctatgaga gattattttg agctttctaa tcggtatgat
    22741 gtgacaaaca aagtcgcatt ttcttctgat cgcaaatggg gcgcgatgga atttccagaa
    22801 ctgggagtcg tgtacgtagg agcgcctgaa cgtttggtgg aagaagatcg gcttccggac
    22861 agtctaaaaa cagcccaagc gaatggctat cgcgtactta tgttagggat cgctccaaat
    22921 cagcaattga acgaagaaaa accagcattt gttgagccgg ttgctctgtt tgaaatcgat
    22981 gatccaatcc gaaaaaacgc tcaagaaaca ctagcttatc ttcatgagga aggtgtggat
    23041 ctgaaagtga tttctggaga caatcctttt actgtctcca atatcgctag acgtgcagga
    23101 ttaccgaatt atgatgcgta tgtcgatctt tctcaaatta ctgaagaaat ggaagtgcga
    23161 gaagctgctc atcgctatac ggtttttgga cgagtgagtc ctcagcaaaa gaaattgctg
    23221 gtaaatgaat tgaaagaaag cggcagaacg gttgcaatga caggcgacgg tgtgaatgat
    23281 gttttggcgt taagagaagc agattgtagc attgctatgg cagaaggtga tggagcaaca
    23341 cgtcagattg cgaatctggt attgttggac tctgatttta ctacattgcc agaagtcctg
    23401 tttgaaggac gccgagtggt caacaatgtg acgaaagtct caggcatctt ttttatcaaa
    23461 acgatttatt catttatttt atcgattata tgtgccgtta cagcaattgg atttccgttt
    23521 atccctatcc aaatcacgct gattgattta gcgattgaag ggtatccttc cttcttttta
    23581 tcttttgaac aagataaaag aaaaatcact taccgttatt tgcctacagc acttattaat
    23641 gctttaccaa atgccttgct tgtagtagtg aatatcattg cggtgtatct acttggaaaa
    23701 acattcgcat ggggaaatgc tgaaactact actttgatgt attacttgct gattgggatc
    23761 agttgcatgg cagttgtaaa agcttgttat cccttcaacc cattgcgcat cttcctagca
    23821 gtaacgacga tcgtagggat atatgtagct gcaatgctgt tccatggaat tttggaagta
    23881 aacttagggt tgggagagag cgtaggatac ttctttgtat tcatgctcgt aaatattgtt
    23941 cttcgagtat tgtactggaa ggctgatatt caaaatcagt tactgaaaag agtagcaaat
    24001 tgatgcttaa tgagatagaa atgtgttata cttgaaaaag caatgaaata tgatacaatc
    24061 aaacatgtat aattgtgtcc tttaaaatcg cactgatttc agttagtgcg attttttacc
    24121 ggttattctc ctgaaatatc ttctgttaaa cccaaaagat atcaatagag cagggggtgg
    24181 aaaaatggct caacggattc ctcaagaggt tatcgaaaca gtacgcagtc aaacgaatat
    24241 cgttgaggtg attggacaat atgtccagtt gaaaaagtct ggtaaaaatt acttggggct
    24301 gtgtcctttt catgaagaac gtacaccgtc tttttctgtt gcagaagaca agcagatttt
    24361 tcattgcttt ggttgtggta agggcggaaa cgtgtttact tttcttcaag aactagaagg
    24421 tctaagtttt ccagaagcag tggtaaaagt ggcagacttc gaacagatac cgttagaaga
    24481 tcaatggcgt cagcgtacta tagctgtcca aaatcctgaa tctgctacgg ggaaactgat
    24541 tgctgctcat gaaaaagcag cggaaatcta tcatcacatg ctattgcata caaaagctgg
    24601 acagccagct ttagaatatt tgcaaagtcg tgggttgtct ttagaattaa ttgaagaatt
    24661 caacataggt tttgcaccta atgagcgttc ttttcttcag caagtattca agaatgaatc
    24721 aatttcaaat gaattgttag aacgctctgg attgtttgtc acgcatgatg atggccgtat
    24781 gtctgatcgt ttttatcaaa gagtgatgtt tccacttcgt aattctcaag gccagacgat
    24841 cggtttttca ggacgctggc ttgcacctga aaaagggcag gaaaaagatc agcccaaata
    24901 cttgaatagt ccagaaacag aactgttcaa taaaagacaa gttttattta atcttgataa
    24961 agcaagaagc gatatccgga aaaacggaga aattttgttg ttcgaagggt ttatggatgt
    25021 gattgctgca tggcaggctg gtatcaaaac tggattagct tctatgggga caagtctaac
    25081 agctcaacag atccaacaaa tggaaaagct gacgaaagaa ttggtctttt gctatgacgg
    25141 agacaacgca ggttttgaag caaccaatcg agggattgaa ttgcttcggc aaaacagtcg
    25201 cttagcactt tctgtcgtag tcgttccaga aaagcttgat cctgatgaat atctccgtaa
    25261 gtatggagaa gcatctttcc aagaattagt ggctcatggg cgcgaaacag tctttacttt
    25321 taaatcacgt tatttaaaac aagggaaaaa tttagataat gaaaaagaca agatcgaata
    25381 cctcgaagaa ttactagttg aacttagccg agttgtttca ccaatcgaac aagatatgta
    25441 tctatctcaa ctgtcaacag agtttcagat cggcagagag acgatacaaa aacaactgcg
    25501 cgatcttcga aggacaaatc agcaaaatcg tcaagaacct caggaaagtc aacacactca
    25561 ggttacgaga caagaaactg cacggaaaaa gagacctttg acgcaagtag aaaaggcaga
    25621 gcagattcta ttatatcgtg catttaaaga agtttctgtc cgtaatattt taaaagaacg
    25681 agaatttcag tttattcatg atgcatatgc agaagtttat tttttattcg atgcatatgt
    25741 ctcacaacat tatgaattca accttgcaga gtttttagac tttttgcaag atgaaaattt
    25801 aaggcggttg gtggtggaaa tcgaatattt accggtggca gaagaaagtt cgccacgaga
    25861 aatccaagac ttgctagatg tgatcagcaa atctggctta gctgatgaaa taacattaaa
    25921 aaaacaaatg cagcaagaag ccagacgaac tggaaacaaa cagcttgagc ttgaattgac
    25981 gattgaaatc atcaatttaa cgaaacagtt aaaacaagcc aaatagctac tcaagggggg
    26041 ccttctttta tggcaaatgg aacagataaa aaaacgtatg aagcagcagt agcagctttc
    26101 atcaaagaaa acaaacccaa acgacaagtt gtatatgatg atttatccaa tcagcttgct
    26161 acaccattca ctttgaatgc agatgaaatg gacaaattga tccaaaagat tgaagacgca
    26221 ggtatcagtg tggtggatga aaatggtgat ccatcaattc acagcttgaa gagtgctgag
    26281 aaaaaagctg aacaagcaaa aacagaagat ctatctgcgc caaccggtgt aaaaatcaat
    26341 gacccggttc gtatgtatct gaaagaaatt ggccgtgtct cccttttaac tgcggaagaa
    26401 gaagtagcgt tagcattgaa aatcgaagaa ggcgaccaag aagcgaaaca gcgtctggca
    26461 gaagcaaacc ttcgtttagt agtaagtatc gctaaacgtt atgtaggacg aggcatgcag
    26521 ttccttgact tgatccaaga aggaaacatg ggactgatga aggcagttga aaaatttgac
    26581 taccgcaaag gatttaagtt ttcaacctat gctacatggt ggattcgtca agccatcact
    26641 cgagcaatcg ctgaccaagc acgtacgatc cgtattccag ttcatatggt tgaaacaatt
    26701 aataaattga tacgtatcca acgtcaattg ctgcaagacc ttggaagaga acctacgcca
    26761 gaagaaatcg gtgcggaaat ggatcttcca acagaaaaag tccgagaaat cttgaaaatc
    26821 gcgcaagaac ctgtttcact tgaaacgcca atcggtgaag aagatgactc tcacttaggt
    26881 gatttcatag aagatcagga agcaacaagt ccagcagaac acgcagctta tgagttacta
    26941 aaagaacaat tggaagatgt actagataca ttgactgacc gggaggaaaa tgtccttcgc
    27001 ttacgttttg gtttagatga tggccggacg agaacattgg aagaagtagg gaaagtattt
    27061 ggtgttactc gggaacgtat tcgtcagatc gaggctaaag cattaagaaa attgcgccat
    27121 ccttctcgtt caaaacaatt aaaagatttc ttagaataag catgaactat tgaccagaag
    27181 agaaatcagt aaaactgttt ggtttatttt aaaagaaaaa aagcttgaga ctacgcagtc
    27241 tcaagctttt ttttctatag gaaggaaatt cattcattat ttttaagtaa atcctaaaaa
    27301 taagctattg gcgtgacgta tagaatatga tagattaaat ggtagcgtaa acctagtaaa
    27361 ggagccgatc gctaagtgat gaaaaaatgt ccaaattgcg gatcgaaaaa aatggagcag
    27421 aatactatct gtccagactg cggtcatcaa ataactgcag aagatcagca aataaaagaa
    27481 tcaattgaag aaacaaatac agatgcagct atgcaggata aatcaactga agatgcagtc
    27541 tttcctgata cagaattaaa cgatccaatc gaatggtcgg aattgaaaga tttacctcta
    27601 gaatctgtaa tggaattatt cgaaaaagca gaaccagaag acgaagaacc acctgctcac
    27661 gatcaagtaa ctaatataga gaaaaatgaa cagaagaaag caactgttca tgagacttcg
    27721 gaagaatcag gaaagaatca agaagaaacg cttgaatcaa aacaaaaaag aagagtagct
    27781 gaactgaaag aaatcgtcga taatgaggaa gaaaattcga tactatccgc ttatatcaaa
    27841 gcacatcgtg aagatacaaa agaagagcac gcgaaagagc tgctcaaaat gatcagtgaa
    27901 aaaattgcac aggaaaacaa agtagagcca gaacatgaag ctgaaaaaga cactgaaaaa
    27961 gacattagtg gagtaaacgc tgcaggtaaa gaatcattaa aaacgaatga tctaaaaacg
    28021 aatgatctaa aaacggatat cccggaaaaa actgaaacat tgtctgaaaa acaatcagaa
    28081 gacgagaaat cgaatgggtt gccggaagca gataaaaaag aaatgctcga aaaagcagac
    28141 aagaaggcaa cagagtcgga tggaataaat aatgaagccg atgctgaaac tcaatctgca
    28201 agtgaagata gcactgctct tgaagctaaa atagaaaaag aagagaacca gcctgagctg
    28261 attgaagcag aaacagaacc aataacaatc gtgccaaata ctgaaaaaac gcctcaagaa
    28321 tcaaacccag aaaaaaaaga tttagataag acacaaaaga aaaaatcaaa aaaagtgccg
    28381 tatctcgctt tagcagcagt tcttctacta ggtgggggag gctgggctta ttatgaccat
    28441 catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca aatggaagaa
    28501 cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat tcgtgcagat
    28561 atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa gaatgaaaaa
    28621 ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg agatatccaa
    28681 aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc agatgacatc
    28741 aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga ttttggaaaa
    28801 ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca aacagctaaa
    28861 gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac acgcgaccaa
    28921 tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc tgctcagttg
    28981 aatgaacaat tgcaacaagt agataagatg ctcactgata aagagaaaaa agaagaagag
    29041 gaaaagaaaa aagcagaaga agcgaaaaaa gcagaaaaag cgaaaaaagc agctgaagaa
    29101 caagcaaaac aagccgctca agcagcagct gcagctcaag ccgctcaaca agctgcggtc
    29161 gcacaagcag cacagcaaga agcggcatcc tcgacccctt cctcttcaaa ctcagcgaat
    29221 cagccaatca aatctgccag agcaagtgat attgccgatg catctaatcc agcatggacg
    29281 tgggcaccag gtgtccaaag caaagtgatt gctacatgta tccaacgtgg atatatcgtt
    29341 gaaggaggat acagattaga aaaagccaga atcgaaaatg gggaaggcta ttacaatcta
    29401 tatgccactt caacaaaatc tgcattgatg aaaggcattg gagaaagtgc tttgccattt
    29461 tacatcgtaa ccatcaactg taaaactgga tggttcggag gaaatgggag caattaattt
    29521 taggcaaatg aaagaggctg tgagcctgcc gtttaacacc gtttattcga aaaaggggag
    29581 tatgacacaa ctgttgtcat actccttttt tcacctttcc aaaccaaggc tcagctattc
    29641 aagtagataa cattatgtta tgatagcaaa gaaatgtatt aagaaaacct ttcactatag
    29701 agggagaaaa aaatgaacga tttattagca actatattta caggtattat tattgatgaa
    29761 aatgaaaaaa actactttgt ccaaaaaaac ggacaaacct ttggcttaag caaatcagaa
    29821 ggtgaacaca aaatcggtga agcagtggaa ggattcggct accaaaatca aaaacatgaa
    29881 aatcggatca ctacacaaat tcctaaaagc cgtatcggtc attacgcttt tggaatcgtt
    29941 actgctacac gaaaagattt aggtgcgttt gtcgatatcg gtcttccaga taaagacttt
    30001 gtcgtatctc ttgatgaatt gccgacaatg acagagctat ggcctaaaaa aggggatcgc
    30061 ttgatgattt cccttagagt tgatgcaaaa gaccgtattt ggggcagttt agcagatgaa
    30121 aaaatattca aatctttaag caaatatgga acagaagaaa tgaaaaacaa agatgtgata
    30181 ggaacagcat accgcttgaa attaacaggt acgtacgttt taacggaaga tttctatctt
    30241 gggtttatcc atccttctga acgatataat gaacctcgtc taggcgagca aataaaaggt
    30301 cgagtgattg gtgtccgacc agacggtgta ctgaatcttt cattgaagcc aagagcatat
    30361 gaagctatat cagatgatgc acaaatgatt ttaaccattt tagaacgttc tgcagatcag
    30421 caaatcaact ttacagataa atcggatcca gaagaaatca tgaaagcttt tggtatcagc
    30481 aaaggagcat ttaagcgcgc attaggtaat cttttgaaac aaggattgat tacacaagaa
    30541 aacggtgtga caaaactagt caaaaaatct aattgagaat cccttgcatg tttttcttaa
    30601 ctagcttata ataattttaa ttaacatagt gttatatctt tttttatttg taattattat
    30661 aaattgttgg ggttgagtaa atggtcatga atgctatttc ggcgatgaaa aaaacaaaac
    30721 agcagctaca tgaagcgggg tttaagctga caccgcaaag agaagctact ctgcttgtgc
    30781 ttttggaaaa tgagaaagag catttatctg cagaagaaat cttcttttta gtgaaaaaaa
    30841 agagtccgga aattggactt gctactgttt atcgaaccct tgaaatcttg acagaattga
    30901 aaattgtcga taaagtaagt tttaatgatg gattagcccg ttatgatttg agaaaagaag
    30961 gcgccaaaca tttccatcat catttactat gcttgaactg cggcacgatc gaggaagtag
    31021 aagaggatct tttacttgaa gtggagcaag tagtagaaga acgttatcat tttttagtaa
    31081 aagatcatcg gctaacgttc catggaatct gtcaggaatg ctatgaaaaa gaaaaaagaa
    31141 accagtccgt ctgagtgtct agacggcttt ttctttgctc agattatgga aaaagactat
    31201 cagaatgaag cggtatctga tatgatagag aggcatgagg gggattatta tgaaagagca
    31261 aatcaacgat tatctccact acttgaatat tgaacgggga ttgtccgcca atacacgaca
    31321 aagctatgaa cgtgatttgg aacagtactt gcattttcta caggagcaga aaattgcttc
    31381 atggcaggat gtcgatcgct ttttagtcat ccgttttctg gagaagttgc atgaagaaaa
    31441 aaaagcgaca gcaactgtta ctcggatgat ctcaagtctc agaagattcc atcagttttt
    31501 acggcaagag cgtatcactg atcatgatcc gatgcaacat atcgatacgc cgaagaaagc
    31561 acagaaatta ccaagtacat tgactctgac agaagtagaa aagctgattg aagcacctga
    31621 tacgacaaaa acgttaggga taagagatcg tgcaatcttg gaagtcatgt atgctacagg
    31681 gatgcgcgtc agtgaattga ttggattgaa attgggagat cttcatcttt ctcttggact
    31741 ggtacagaca gttggaaaag gagataaaga gcggatcatt cctttaggtg attatgcgat
    31801 ccaatggctg gaacgctact tagacgaagc acgtccatta cttgtaaagg acgcatctga
    31861 aatgcatgta tttgtcaata atcatgggaa aggtctttct cggcaaggaa tctggaaaaa
    31921 tctgaagcag ctagtacgag aggctgggat ttacaaagaa gtaacaccac atacgctgcg
    31981 gcatagcttt gccacacatc tgctagaaaa tggagctgat ttgcggacag tacaggaatt
    32041 gttaggtcac gcggatatct ctacgactca gatttataca catatcacga agaaaagaat
    32101 gacggatgtt tataagcagc attttccaag ggcttagtca taggaaggtg agaagatgtt
    32161 aacacattac cggaaagaaa accgtaaaat tgctatggga ctattgagtt tccataagaa
    32221 actgacaggt aaaacttctt tgttgaagga gattgatacg tacgaatctg aagacgatta
    32281 tgaacttttt ttctttacgc cagaaggttc aaccaacatt caagggatta ttggtgttta
    32341 ctgggcaacg aacgatcagc tgatcatcca tgacatttct ttgaatccgt cttatcgcgg
    32401 tgagaatatg ggctttcaaa tgttagatga attacaggaa aagtacccgg atgtctccat
    32461 ccgtgcaact gaaatcacag agccttacat tggaaaatgg ctagcaaaga aaaagaagaa
    32521 agagtgaatg agttgacgga gatcaatatt aaattagatg tattcgaagg tcctctcgat
    32581 ctgctgcttc atctgattca gcaaatggaa atcgatatat atgatatacc gatcgctacg
    32641 atcacggagc aatatatgaa ttatatccat acaatgaaaa cactagagct agctgttgca
    32701 ggagaatact tagtgatggc tgctacattg atggcaatca aaagcaagac attgcttcct
    32761 gtccaagaat tcgtcacaga tgatgaagaa ttatgggaag aagatcctcg agaagaattg
    32821 gtcactcagc ttttagaata ccgtaaatat aaatatgcag ctgaaagact gacagaaaaa
    32881 gcagaggaac gaagtcttta ttacacaaaa gaacctatga acatcgatgg gttagcggat
    32941 gctgaaaagc cgttgaagcg aggacaagtc aaaaaaatcg atttgatccg tgccatgcag
    33001 aaaatcttag aacgtaagaa attttctcaa aaagtggaaa aaacgatcac gcccgatgac
    33061 acaacgatcg aagaacgaat ggtatttatc gaagagcgta taaaaagaaa tgcgcatggc
    33121 tgtactttcg attctttttt tgagtcacct tctaaaagtg aagttgtcac tacttttatg
    33181 gctttgctag aattgatgaa aaaagggcag atcattgcgc aacaaaaaga aaactatgaa
    33241 tcaattatgc tttatccagc agtaggagat accgaacatg acgaaattaa gtgaacttga
    33301 agcccttctt tttattgttg gcgaggaagg gatcagtaat gaagaattaa gcggactgtt
    33361 aaatctcagc gaagcagaag tcacaagttt agtgaaagaa ttaaaagaat cttacactca
    33421 aaactcgcac tcagctttgc atatttttga aacggaaagc cattatgtat taacgactaa
    33481 aaaagagctg gctcccttac ttaagcgata tgcgcaaggg acatcaaaca cattatctca
    33541 agccgctgtc gaaaccttag caatcatcgc ttataaacag ccaatcacaa gagctgaaat
    33601 cgagcagatt cgaggagttc aggtttcagg agcggtacag cgtctagctg cccataaact
    33661 gattgaagaa aaaggtagag tagaagggcc aggtcggccg atattatatg gaacaactgg
    33721 ctacttctta gattattttg gtttgaaatc attagaagaa ctgcctgata cacaagaaat
    33781 ggaaatttca tttgaagaag acgtgtcacc agatctattc tttgatggaa tgaataaagg
    33841 agaataattg taatggaaag attgcagaaa gtaattgccc acgctggcat cacttctcgt
    33901 cgaaaagcag aagaattcat ccttgcagga cgtgtaaaag taaacggaca agttgtaagg
    33961 gaattaggga taaaagttgg gaaacatgac actgtggaag tggatgaagt cccaatttat
    34021 caagaagaat acggttatta tttattgtac aaacctaaag gagttatttc tgctgttgca
    34081 gatgacaaag gaagaaaagt tgttacggat cttttgccga tggtaaaaga acgtatctat
    34141 cctgtaggtc gactggatta cgatacttcg gggatcttgc tactgacaaa tgatggagat
    34201 tttgctcagc gcctgacaca tccaaaacat gaagtggata aagtttacgt tgcaaaggta
    34261 aaagggatcg ctacaaaatc gatgcttgca cctttgacaa aaggaataaa gatcgaagga
    34321 cgaaaaacat ctccagctaa attccaaatt ttatcagtgg atcctaagac aaaccacagt
    34381 atcgtggaat tgacgatcca cgaaggacgt aatcatcaag tgaaaaatat gcttcaagca
    34441 gttggtcttc ctgtgcaaaa actaaaacgt gaaaaatacg gagatctgac tttacaaggc
    34501 ctacgtcctg gagattaccg tgaactgaac aaaaaagaag tcagcagttt gctgaaccac
    34561 tcaaaatgaa cacttacttt ttataagtgt tagatgttgc gttttttgaa tagatatgta
    34621 taatgaatat gtaaacaaaa attatataag gttcgtcttc aggggcaggg tgaaattccc
    34681 gaccggtggt tatagtccac gacctatttt gcaaaaaata gctgaatcgg tgaaattccg
    34741 ataccgacag tatagtctgg ataaagaaga tagagcttat ttgacgacgc ttgatcaaat
    34801 aactctaact ctattttccc tggaaaatag agttttttca tttggagaga aacgtcaaaa
    34861 agttcgctga agaggagtcc taacaggagg atttcaaatg aagaacaccc gtgtacagaa
    34921 aatggttgca gtagcgatgt ttgctgcgat cgcgttagtt ttacagtatt ttgcttttcc
    34981 gatcatgccg gcttttagtt ttttgaagat cgattttagt gatatcccgg tattgatcag
    35041 catgttctta ttcggtccag cggccggagt tgcaacagcg ttcttgcgtt cagtattaca
    35101 tctgctgact acaggttttt ctccggataa tttggtagga gacactgcta gtttcttatc
    35161 aacaacgatc tttacattcc cgatttatta tttctttagt gtaaagaaac agcataaagg
    35221 aagaaacaaa tttttaggtg tcattacagg aaccatcgct ctaactattt ttatgagtat
    35281 cgcaaattat ttcgttatta cgcctcttta cttaatgttt ttaggactga acgcaacaca
    35341 gatgctaggc atgtctttag caaactatgt actgattggg atcgttcctt tcaacttgat
    35401 caaaggattc atcgtgagcg ctgtcttttt agtgctgcat gcgcaacttc ttccatggtt
    35461 aagtcgaaaa caacatcagt tcgaacaacg tcatacagca gtcaaataat tatcaaaaag
    35521 atcaagaaat ttcttggtct ttttttttgg aaaaaaatac aagacatgca ataatgtaaa
    35581 cgttttattt gtttgttttg agtatttttt tgatttatgc ataaaaatca atcaattctt
    35641 tgcaaatgtg aaattcttct ccttttaaaa gacgaaaatg tttgtttata aaaaaaagga
    35701 aacgctacaa tgaaaaagaa gaaagcttta aaaacctgaa aaaagaggag ggaataggga
    35761 aaaacgaact ttttgaacaa aagttttaca aaatgcgtgt tattattttt gttctgatac
    35821 tctttttgat aaaataacat tagagccaaa attgttgtct ctaacggaaa agaaaggaag
    35881 aagaagatgg aacaaacaaa aaagaaaaaa tttcaaatgc cttcagcgta tacggtctta
    35941 tttattatta ttgcagtaat cgctgtactt acttggttta taccagctgg gcactatagt
    36001 gtagacgatg caggcaacat cgtcgctgga tcatatgaac gagtacaaca aaatcctcaa
    36061 gggctgtggg atattttcat ggcgccaatc aatgggatgt taggtgtacc agcgggggag
    36121 ctaactaaag aaacacctgc tgcaatccca atctctttct tcattttggt tgttggtgga
    36181 tttttaggta ttatcaacaa aacaggggca ctagatgccg ggattgcttc agttgtgaag
    36241 aaattcaaag gaaaagaaaa aatgcttatt ccagtattga tgctgttatt tgcattaggc
    36301 ggctctactt acggaatggc agaagaaacg attccattct atgctttact gatcccagtt
    36361 atgatggctg taggctttga tacagtagta gcagtagcaa tcgtattagt agggtctcaa
    36421 gtaggctgtc tagcttcaac ggtaaatcct tttgcaacag gcgtagcttc acaagctgtt
    36481 gggatttcga tgggtgaagg tattggtctt cgattcttga tgttcgttat tttgttagct
    36541 atttctattg tatatgtgta tcgttatgca tcaaagatcg aaaaagatcc aacaaaatca
    36601 ttagtataca accaacgtaa agaagatatg aagcatttcg atattgaagc aatcggtcgt
    36661 caagaagtaa tcacgaaaaa acaaaaacat gttaatgtat tgttctttat tacttttggt
    36721 atcatgatca tcagtttgat tccttggaca accttgaatg cgaatttcac gatttttgaa
    36781 tcattgacaa actggttaac aaaccttccg gtactaggta ctgttctagg taaaagcatg
    36841 cttccattag gtgactggta cttcccagaa attactatgt tattcttagt aatgtccatc
    36901 gtagtagcaa tcacttatgg catgaaagag tctgaatttg tctctgaatt tttagctggt
    36961 gcttctgatt tgatcggtgt agcaatcgta gtagctgttg ctcgtggtat ccaagtggtt
    37021 atgaacaatg gattaatcac agacaccatc ttacattggg gcgaacaagg attaagttca
    37081 ttatcttcaa gtgtattcat cattattaca tttattttct atatccctat gtcattcttg
    37141 attccttcaa cttccggctt agctgctgca acaatgggaa tcatgggacc tatgggtgaa
    37201 tttgccggcg tcggtaagga tttagtaatc actgcttatc aatctgcatc tggtttagta
    37261 aacttaatta caccaacatc tgctatcgta atgggtgctg tagcaattgc tcgtttcgat
    37321 gtttcagtgt ggtggaaatt taccggtaaa ttaattgcga tattatttgt agccatctgt
    37381 gtgatcctag gtgtagcagc aatgttctaa acctagacaa atacaggtac aaggtctatc
    37441 ataagaatga agaaaccgat aaacggctat cgataagcac gtggacaagt caatagctcc
    37501 attcagtgag tgttttttct ttcatcattt gttaagaaca ttctgcttgc tgatggagca
    37561 ggcttaaaac gtcattattt gagaagaaga ggttgtgtcg gaggaatttg acatgaccct
    37621 ttttaacata ttaggaggat aatatcatga aaaaatttgt gacagaacaa catcatgaac
    37681 aagcattaga atcattgagc gaattgatcc gaattccttc cgtactagat gaagcagatt
    37741 caggacaagg acatcccttc ggtaaaaaag tgattgaagc tttggataaa gtattggaaa
    37801 tcagtgaaaa gctaggattt agaacattta aagatccaga aggctattac ggttattcag
    37861 agattggctc tggagatgaa ttattcggta tcttgtgtca tatggacgtt gttccagcag
    37921 gggacgaaaa taattgggaa acaaaaccat tcgatccaac tataaaagac ggctggttag
    37981 ttggtcgcgg atcccaagat gacaaaggtc cttctattgc ggcaatgtat gccgtcaaag
    38041 ctttgattga tgctggcgtg gaattcaaga cacgtattcg ttttatcttt ggtacagatg
    38101 aagaaaattt atggcgttgt ttagaaaaat ataacgaaaa agaagaagga attacgcaag
    38161 gatttgcgcc agatgctgaa tttcctttaa tttatgcaga aaaaggctta ttgcaagctt
    38221 acttgacagg accaggaacg aacgagtttt ctgtaaaagc tggaggagcg ttgaatgttg
    38281 ttcctgatgc agctccttac tctggagaaa agctttctga agtaaaagaa gcgttgaaaa
    38341 aacacgaatt cgatttcgaa gaacaaggtg aaggcatcgt cgttcttggt aaaagtatcc
    38401 acgcgaaaga tgcagcacaa ggagtgaatg ctatttctcg tctggcaatt gctctttcag
    38461 aagtattcga ttttggccca atcaatttct taggaaaatt agttcaagaa aatgcaactg
    38521 gtgaagctgt cgtgggcaaa acagaagatg aacaatccgg cgagctaacg atgaactttg
    38581 caagtttgga aatcacacca gaacaaacaa aaatcggtgt agatatgaga atccctgtta
    38641 cattcaagaa agatgattta gtagctaaat taactaaaac agcagaaaaa tatgggttga
    38701 cttatgaaga atttgacttc cttgattcat tatacgtgcc actagacagt gagttagtga
    38761 aaaatctatt ggggacatat cgcgatatta ctggagacat gactgaaccg tttgtatcag
    38821 gcggcgctac ttttgctcgt acgatgaacc agtgtgtggc attcggtgcg atgttccctg
    38881 atactcctga ctttatgcac caggcgaatg aacgatggga attaagtagt atgtataaag
    38941 caatggaaat ttatgcagaa gctgtgtatc gtttatgtgc taaataaaaa taaacataca
    39001 aaaagggcgg atattcaaat ggatattccg tcttttttta tttgatgctg gaaagtttgc
    39061 atttctctct tatttttttt aaggtataat catacttgat taagaaaaag gggtcactca
    39121 gatagaaaag gtgggagaaa gtgaaaatat ttagacgaat actaattggc ttagtcatca
    39181 ttttaggatt actcggtgga gccggttatt actatataca gcaaaatacg tacgaaccat
    39241 cgtcagaagc gcaagtgttg gtaaaagaag gaaaaaacaa agaagattac ttattttttg
    39301 aaggagagaa aaagaatcat ggaaattctc cattacttat tttttatcct ggtgctctcg
    39361 tagagccaga aagttatagt atttgggcgc aagatttagc aaaaaacggc ttttcagtcg
    39421 ctattgtcaa aatgccactt gatctagcag tgatgggcgg aaacaaagcg gataaggtca
    39481 aagaagattt tccaaattcc gattatgtga tcggtggcca ttcattaggt ggcgtaatgg
    39541 caagtcgtta tgtcaataag aatcattcag acaaacattt aaaaggggta ttcttcatgg
    39601 caagttatcc cgacaaaaaa ggaacattga cagaatcagc tgttcctgtt ttatcgatca
    39661 cggcgacaaa agataaagta ttgaatcagg aagcttatca agaagctaag cagtatttac
    39721 cggaaagaac agagtatgta tcaatcaatg gcggaaatca tggaggtttt ggcagctatg
    39781 gtgagcaaaa aggagatgga gaggcagaaa tttctaacgc agaccagcaa actgtgatcg
    39841 tcaatacatt ggaaaactgg ctgaaaaagt tgaaataata taaatgggtc ctatagggtc
    39901 cgtgaaaaaa ctagtcaatt aactatagat agcaaatgaa tctttcaaaa taagtcggga
    39961 tttcacggaa caagagaaac agatcccggc ttattttcaa gtttagagaa cttagtgtac
    40021 gtttttaaag tttcgtttat atttatattt tattttctaa taaaatcgct cgaactggac
    40081 atttttgata cgcttttttt acatatgttt cttcttccgg catcacgaac tgttgatgag
    40141 cctctggttc ttgggcaaat aaaacgattc cttcttcatc ataatcgaaa atatctggcg
    40201 cttcgatttg acaaagaccg catgcaatac agcgttcagg tacaagttta catagtagtg
    40261 acatttctaa ccatcctaac ttaaggagaa taatatgatt gtttttattt tatcgctatt
    40321 ttcatcagga cacaagctgc ggattagttc tctttaccaa ctccttgtgg gaaaacgaac
    40381 gacttcagta cttatttatg gatttaccca cgaacttttg tttatccata acagttttcc
    40441 agaattgaag caggataagt tttatcaaat tttgcaaaaa attgcgcagc aaggttggat
    40501 cgaaataaat gaaaatgaag caaagctaac gcctgcaggg gctgatatgt tgtccgaaca
    40561 tcaaatagaa catactggtt tgcgttttga ccgctatggc agaacagggg aaactagttg
    40621 gcggctcatt aaatttgctg ttcaagtaat ttctaatctg gcaacgggta ttcaagacta
    40681 tcttccagca gagacaagtc ctttttatac tttccaacta aaaaaatggc ttagtgaaag
    40741 ccaattgcca cgtgaaattt tgattgatac tgcgtatgag agtttggtgc agctgttttc
    40801 ggagatacca gaagaagcag cagatttttt agctaaccaa ttatctggaa atgagcgaac
    40861 agggctgctt ccttatcagc tggcaaaaaa caatgatgag tcagcggttt atctgcaaca
    40921 aagcagatgt atccaccttt tgttagcaca aatcgaaaaa cggccagatt cgctttggca
    40981 cgctttgatc gattcattat tacagcaaaa tttcaatcaa agcatgatga tcaccaagca
    41041 gatgtttatg aatggtcaga caattgacca gattatggca atccgtcatt taaaaagagg
    41101 aacagtaaca gatcatctta ttgagtgggc cttgtttttt gatgattttc catacgagcg
    41161 gattctctct gcagaaacaa tcgaacgttt ggaaccaaat aaggattccg tgcgagagtg
    41221 gcgctttagc gaatggaatg tagatggaca attagattat ggagaatttc gtttgtatca
    41281 aatctatcta ttgagaaagg aagcgataca gaatgttaat aaatgaatta aaaaaatatt
    41341 ttggatttga ttcatttcgt cccggccaag aagaaatcat tcaggcgttg cttgatggag
    41401 aagatactct cgctattttg cctacaggaa cgggaaaaag cctttgctat caattgacgg
    41461 ggtttttaat ggaaggtctg gtcatcatcg tgtcaccgct gctttctcta atggaagatc
    41521 aagtgacgca attacaaaaa cgaggggaga aacgagtagc tgctttcaat agtttacttt
    41581 cgcaatctga aagaagatac gtcctccgtc atctatcgca atataaattt ttgtttttga
    41641 gtcccgaaat gttgactaat ccttctcttt tagagcatct gaaaaaacaa aatattgcgt
    41701 tatatgtagt agatgaggct cattgcgtgt ctcaatgggg agttgatttc cgtccagaat
    41761 atcaacagtt aggaaaaatc cgaaagcttt taggaaaccc ggtcacactg gcactaacgg
    41821 cgacagcaac agatttagta gcaagagata tacgtcatgt actatttgat cgaccaccaa
    41881 aagagatcag acaatcagtc aatcggcaaa atatctcgct ttttgttcgg aaaacgcagc
    41941 aaaaagaaca agaacttgaa cacttcatgg aaagagcaca aggagcggca atcatttatt
    42001 gtgcaacaaa aaaagaagtc gaacgattgt atcatttatt cagggaacgt tttacagttg
    42061 gatactatca cggtggtctt gatgcagctc aaagaagaca acttcaacag cagtttgtaa
    42121 aaaatcagct gcagtttctc attgctacga atgcatttgg tatggggatc gataaatctg
    42181 atatccgtta tgtgatccat tatgatttgc cagacagtct agaaaactat gtacaagaaa
    42241 tcggtcgagc aggcagagat caggaagaaa gtgcagcaat tcttttttat caaagtgggg
    42301 atgaacgtat ccattatttc tttaatcaac tttctagaga acagcgacaa agttttgagc
    42361 tttatttgga atatgccaca gagcaagctc cctttgatga gctgcaaaaa aaatggatgg
    42421 agctgatcca gcagtctgaa aaaccagaaa attgggtgga acggctcaaa catcaggaaa
    42481 aagaaaaaga attccgcctg cagcagatgc ttcgctatat taatgaagaa aactgccgca
    42541 gaaaattcat cttagcttat tttggcgaaa aactctccga aaagccgcag aattgttgtg
    42601 atattgatgg agcaaaagca gaacttctgc caaagaggaa gcttttttct aagactgaac
    42661 aacttcattg ggaaacgatt ttactaaatt tatttaaaaa aaacatggaa cattgatttt
    42721 ttaggacaag acactttttc ctatggtata atacacacga tagagtttag gaggtaaaac
    42781 agtgagcaga aaagatagac atcaatctac agaaaataac gaaacacaag aaccatggga
    42841 acaaccaatc tacgatacag atgatgaagt ttcatcaaga agttctcaga gacaacaaaa
    42901 gaaaggaaat acattatttc tttcgctatt tttgatttta ctggtcttat gtatcgctat
    42961 tccagcaggt gcttatttct ggatcagaaa tggatcaagc aacaatgcaa cagcagcaac
    43021 ttcttctgaa acttcgacat cagtagtaga aagttctaca agtacaacaa aagaggagtc
    43081 aactgagact tcaacagtag aatctagtac aatcgcggaa gaatctactg tgtctcaaga
    43141 tacaggtgta acgtcagaaa gcagtattgc agcagagaca acaccgactt cctcaagtga
    43201 ggcaacttat caagcagggg attcaagcag caatgcagca gaaacaacac cttcttcatc
    43261 agctgcagcc ggttcaacaa cgactgttca agcaggcgaa ggtccaaaac aagtggctga
    43321 gcgtgcaggg atcaccactg atcaattgtt tgaattgaat ggcttagatc caaacaactt
    43381 tatgctttac cctggtcaag aattaagaat taaataataa tagccgcgct ttgcggcttt
    43441 tttttgagaa aaaggagtta tatcatgaca caaatcagta ttgcaatcga cgggcctgct
    43501 tcatctggga aaagtaccgt tgccaagata ttagcaaaag aattgaatta tatttataca
    43561 gataccggtg ccatgtatcg cgcagtaact tatttagcta ttacgaacaa tgtatccttt
    43621 tcagatgaag aagggctagt ttcgctgatc aaaaagtatc ctatctcttt ttcgcaacaa
    43681 gaagatggac agcatgtatt catagcatca aaagatgtga ctttagaaat ccgtcaacca
    43741 gatgtcacaa aagctgtttc tgaagtctct gcacatggaa aagtcagaga agaattagtt
    43801 gctatccaac gaaaaatagg ggaacgcggt ggcgttgtca tggacggaag agacatcggg
    43861 acagctgtat taccgaatgc agaagtgaaa atctttttag tagcaagcgt aagtgagcgt
    43921 gcagaaagac gtttcaaaga gaaccaagaa aaaggaattc cgactgatct tgaaacactg
    43981 acgaaagaga tacaggaaag agaccattat gattcaacaa gggacgtctc tccgctgaag
    44041 caagcagagg atgctgttcg tatcgatacg actggcaaat cgattccaga agtcgttgca
    44101 gcaataaaag ctgttgtttt gaaaaaaggt tatcttcttt tttaaattaa gaaaaaaaat
    44161 gaaaaacaat tgttttttca aggaaaacga acgaaatcgc tttatttttt ttgaataatc
    44221 aattaaacta aaaacagtac cgtacttacg gcagaatgtt ggttaggagg acaagtgtta
    44281 tgacagaatt tgatcaaaat caagagaaca accagtcaat ggaagacgca atgaaaagcg
    44341 tacaagaagt aaaagttggc gatgttgtta agggcgaagt tttagtcatt gaagacaaac
    44401 aagtgattgt cggaatcgaa ggggctggag ttgaaggagt cgttccggca aaagaattat
    44461 caactttgcc ggtagaagat atcagcgaag tagtaaaagt cggtgatgta ttagacttag
    44521 tcgttatcag tacgatcggc aaagataaag aaaacggcag ctacctactt tcaaaacgcc
    44581 gtttagatgc taaaaaagtt tgggaagata tcgaaagaga tttccaagag ggcaaggtga
    44641 tcgaagcacc tgttacaaat gttgtcaaag gcggtttagt cgttgacgtc ggtgtacgtg
    44701 gttttgtccc tgcatcaatg gtggaagatc attttgttgc agacttttca gactataaag
    44761 gcaaaacatt gagctttaaa atcatcgaaa tcgaaccatc agaaaatcgt ttgatcttat
    44821 cgcataaagc ggtagtggaa aacgaaagag aagaaaagaa aaaagaaatt ctttcaacta
    44881 tccatgaggg agatgttctc agtggacgtg ttgcacgtct tactgatttt ggcgcatttg
    44941 tcgacctagg cggaattgac ggtctagtcc atgtctcaga gatttcacat agtcatgtag
    45001 caaaaccaag tgatgtattg gctgtcaatg atgatgtaaa tgtcaaagtg ttgtctatca
    45061 atcctgaaca agaacgtgtt tccttgtcca tcaaagacac acagcctgga ccttggtcag
    45121 aaatcgatac aaaagctcca gttggcacag tattagacgg aacagttaaa cgtttgacaa
    45181 gcttcggtgc ctttgttgaa gtgttccctg gagtagaagg gctagtccat atctctcaaa
    45241 tttcacataa acatattgcg acaccacatg aagtgcttca tgaaggtgac gaagtgaaag
    45301 tgaaagtatt agagatccat ccagaagaac atcgtattgc attgagtatc aaagctttag
    45361 aagaaaaacc agcttcagaa gaagaaccaa aaaatgttga gtcttatgaa ttaccagaag
    45421 aaaatactgg atttactatg ggagacattt taggtgatgc gttgaaagaa gaagtagaag
    45481 aaaaagcaac cgatgattct gaaaaataat tgattttgta tctgtgactg agatgaaagc
    45541 agctgctttt gtctcagttt ttcttttgaa aagcgattag tatttcaata aggaataaaa
    45601 atacttcgtt taattgacaa tctatgcttg aaagttggca atgcattcgt taaactaagt
    45661 gagattggaa acttgtgagg aggaaataat atggcaaatc caacaattgc aatcgttggc
    45721 cgcccgaacg tcggtaagtc tacgattttt aaccgcatcg ctggtgagcg tatctcgatt
    45781 gtcgaagata ctcctggagt aactcgtgat cgtatttatg caaaaggtga atggttaggt
    45841 cgagaattca gcgtgatcga cacaggcgga attgatcttg gcgatgaacc ctttatggat
    45901 cagatcaagc atcaagcaga aatcgcgatt gaagaagcag atgtaatcat ttgtgtagtc
    45961 agcggacgcg aaggcgtgac agacgcagat gagatggttg cgaaaatttt atacagaagt
    46021 aataaaccag tgattttagc agtcaataaa gtagataatc cagaaatgag aaacgatatc
    46081 tatgaatttt attccttagg gctaggcgat ccttatcctg tttcaggaag ccatggacta
    46141 gggattggtg atattttaga tgaagcagtg aagtatttct ctgaagagac tgaagaagag
    46201 gacgacgaca cgattaagtt tagtttgatt ggtcgcccaa atgttggtaa atcctctttg
    46261 atcaatgcga ttttaggaga agaacgtgta attgtttcgg atattgaagg aacgacccga
    46321 gacgcaatcg acacccactt cgtttctgaa agtggtcaga aattcttaat gatcgataca
    46381 gctggtatgc gtaaacgcgg aaaagtatac gaaaatactg aaaaatacag cgtgatgcgt
    46441 gcaatgcgtg ccattgaccg ttctgatatc gttttgatgg tactgaatgc tgaagaaggg
    46501 attcgggaac aagacaagcg agtagcgggt tacgcccatg aagctggtcg tggaattatt
    46561 atcgtcgtga ataaatggga tcttgtaaag aaagaaacca atacaatgcg tgatttcgaa
    46621 caagagattc gtgatgaatt ccggtatctt gattacgctc caatcgtttt tgtttctgca
    46681 gtgactaaac aacggttgga acgtctgcct gaaatgatcg aacaagtaag tatgaaccag
    46741 aatcttcgta tctcttcggc tgtgttgaat gatatcatta tggatgctgt agcaatcaat
    46801 ccaacaccaa cagataaagg aaaacgcctg aagatttttt atgctacaca agtcgctgtc
    46861 aaaccaccta catttgtcgt ttttgtcaat gaagaggaat tgatgcattt ttcttatgaa
    46921 cgtttcttag aaaatcaaat cagaaaagca tttacttttg aagggacgtc catccgaatt
    46981 atccctcgta ggagaaaata ggcattttac catatcgacg tttttttttc aaaagaaaaa
    47041 gacagtttcg tttgttacgt ttctatgact aaaaaaagta tgtgaaaatt ggtaaaaacc
    47101 ttgctattaa gcggttcata tgatatcgtg ataacagaat attgaagtta atcaatattt
    47161 ctttttaaac ttctggacca ctcagaaagt tttaactaaa tgatatttct atcatatctc
    47221 ttgtggagga ggtgaatcta tccatggcaa acaaagcaga attaatcgaa aaagttgctt
    47281 cagctactga tttaactaaa aaagatgcaa ctgcagcagt agatgctgta ttttcaacta
    47341 ttcaagatgc tttagctaac ggcgaaaaag ttcaattaat cggttttggt aactttgaag
    47401 ttcgcgaacg cgcagctcgc aaaggtcgca acccacaaac tggtgaagaa atcgaaattc
    47461 cagctagcaa agtacctgca ttcaaaccag gtaaagcatt aaaagacgct gttaaataag
    47521 acagttgaaa aagcgcttgt ggctctaggg ctacaagtgc ttttcttttt atttcctagc
    47581 agaaaaggaa taaataagag acagagattc cgaatccgta tgtcatacat agaaaacaca
    47641 tgtattttat ttaattttta tttatttcca agttatgagg tgagctttgc tcttatcttt
    47701 tctagaattt gcttactaat ggtaaaataa aaataagaag aggagggatg cgtatggaac
    47761 ttgattatca agtagaagat gcgttgacga aagtgtttta cggagaaacg ctagtcagcc
    47821 agctaagaga actttccatt gatcagccaa tcttattttt aacgaatcag cgctattatg
    47881 atttgtttgc agataagatc aacccgttat ttgcaaatca agcaaacaat gactggtata
    47941 tttgtgccaa cactcaatgc aatcatttaa cagaattaaa gaacctgctt gatttcgtca
    48001 aacgctatcc cgaaaatcaa tccatgttta tcatcggatt tggaaatgaa gggatcatgg
    48061 atctggcagg tttttttcaa aaacatacaa cccttgattc atcactatgg atgatccctg
    48121 tatcgatccg ttctctaagc cgagcattaa caccgcagcg gacgattttg cagctaccaa
    48181 atcgtgtagt actgcaaacc atcaatctgc cagaacgcat cgtttatgat caaacaatca
    48241 gcgagcggca agtggacgga aagcagattg actttttgac ttttatctgt tgcggaatga
    48301 tttgtgatca tcgttttttg caaaatctgt ataaaaacta tccaaataaa aagcaattaa
    48361 cgactcggcc gtttgccggg atgatcgaag aaatgatcta tttttatcaa ttagaggcag
    48421 aaaacctgtc aaattatggt aaactgtttg aacaagcttt ttatctgacc gaaaatggcc
    48481 atctactttc tgctagtatg aaaaaatttt taggaatgat gtttcatttc gtgtggaatc
    48541 tccaagcata tccttttgat ttccaactaa aaaacttttt tgtgtggctg gacttgcttg
    48601 gctatccaat ccactggctg gaacagattt caaagatgga gtatttggaa aaagttcttt
    48661 ttttggcaga aaaaagcaaa aaaatacttg ttttagaaaa aataggtata atagacggat
    48721 accaacgtcc aaacgaaaaa gaattattga gaacaatgac ggtatttcaa caaatcgtca
    48781 gtgagataag agggaattga aatgaataca aatagcgaaa aaatgttgca agctttatca
    48841 gatgaagact tgtcacaagc acaaatcttt ttagaaaaag cattaaaaga agacccagca
    48901 gatatattag ctgaactagg cgaagaattg ctggctattg gctttttgat cgaagcaaaa
    48961 cagatttttg aacaactgat caaccaatac ccagaaaatg acggactgaa catcccgtta
    49021 gcagaaattg caatcgaaga taatgagatc gacttagctt ttgaatacct ggaaaaagtg
    49081 gataagcaaa gtgattacta tccgcaaagc ttattggcga tagctgattt gtaccaagtt
    49141 atcggaatcc ctgaagtgag tgaagcaaaa ttgaaagaag cagctgggtt gcttcctgat
    49201 gaaccattga tccagtttgc gctagctgaa ttgtattttt cagttgatcg tttcaaagag
    49261 gcagcagtgg tttatgaaac attgttggca agcgggataa atgaaatttc aggaatctcg
    49321 atgcaggaac gtttaggaca atccttaagt atgcaaggag aattcgaagc agctatcgca
    49381 cctttagaag aagcactgaa agaagaaagg acagatgatc gactgttcca gctagctttt
    49441 acgaatcttc aattgaaaga aaatcagcag gcaatcaact atctggaaga acttcgagaa
    49501 gttaatccgc attatcaatc gttatatcta tatctaggac aagctcttca agaagaagaa
    49561 atgattgaag aagcacaaac agtgttagaa gaaggaatca aagaaaatcc ttaccaagtc
    49621 gaactttatc acctggcctc ggaaaatgct ttccgtctgc atgatagaca gcgagcagaa
    49681 gaacttttac tgaaagcttt agaagtagga gacaaacaag atgaaacatt acttacttta
    49741 agcaatcttt acttggatga tgaaagatat gaagatgtga tacaagtgat caatcagatg
    49801 gaagaaactg ctaatcctta tgcagaatgg aacctagccc atgcttataa tgaattagaa
    49861 gactttaccg ttgcagctgt acactatgaa caggcttatc atgaactatc acatgaacca
    49921 gatttcttga aagagtatgc ctttttctta agagaagaag ggcagctgaa aagagcgcaa
    49981 gaattattga cttattattt aacacttgaa ccaggagata tggaggcact gtcattatta
    50041 gatgacctaa cagagaggtg agaaaaatgc taattgatgt acgggaaaag aagaattttt
    50101 taacgtggat ggtcaatcat gtatctttta gccgaagaga agttttttgg atcttgaatt
    50161 atcttgccaa tcatgaagcg attttaagca atgtccactt tgttgaaggg gcgaattttg
    50221 cggatcgagg actgcagatc agtgatctat ctgttgaagg ggaacccatg aaattgtttt
    50281 tgcagggaaa agaatttacg gacacagacc agatttttca tgaaatccgt ttgaattgga
    50341 aaaagccttt atatgtggaa tgtatattcg aaaatgcttg gcagacaaga gaatatctat
    50401 ctatcttaga agacaatcca ttttcttctt gggattcttc agtcagtgaa gaagatactg
    50461 aattaattga acgatatttt caagaaaaag aagaagaggc aaaactaaaa atgctttatg
    50521 ctcaaatcga tcaagcacta gaagatggag atagggatgc ttttttgaaa ttatctgatg
    50581 aagttaaccg aaagatcctt ttgcagacac aaaagaaaag taaccgggta agtgaacata
    50641 acaattagtt aaaaatagta tagtactaaa aaagacaaag atcagctgga tgtggaatct
    50701 ttcctcatag cctatctttg tcttttttct tatagttttt tcagtaatct tgtctgtggc
    50761 ttcaaataag taaagccttg cccttccact tcatgcacat tgatgattga aaggaaagct
    50821 ttttcgtcaa tctcgtggac gatcctctta gcttcagtta attcactaga gctaacgacc
    50881 atatagatga ttttttttga attaccagag aatgcgcctt ctccagaaag aaaagtcaca
    50941 cctctttgca gaccggtcat cagtagtggt gcaatctctt cgcttttgtt ggagacgaca
    51001 agtagacctt ttgcagaata tccgccatct aagatcgaat caatcacacg actgaaaaca
    51061 tacgaaacaa tcaacgtata catcatacgt ttcaagtcga tataggttaa tgaagcaagt
    51121 aagacgatga tatcaaatgc caatagggaa cgccccatag tgatgccgta attttgttct
    51181 aaaatccgag caataatatc gctgccacct gttgttccac ccatgcggta gacgatcccg
    51241 cttcctacac ctgcaactaa acccgcaagt agagaaacga tcagtagatc atgctgtaaa
    51301 ttgatttcta gtggaaccct ttgccagatc cataaaaaga atgacaaaga aagtgtacct
    51361 agaactgtat aggccaagga acgtttaccg aggatctttc ctcctagtaa aatcaatggg
    51421 atgttgatta ataaagtcgt ataagctgga tcaattccga ataaagctct taagatcaag
    51481 gtgatccctg agacgccccc ttctgctaaa tgattagcga tgttcaagta aacaagacca
    51541 aatgcataaa tacttgttcc tataatgata aaaagaactt cttttactgt ttttcgtttg
    51601 accatatgaa ttccagcttt caattatgta ttttcacaga atttccattt agaaattcct
    51661 ttctaaatgt agcatggaaa ttcgattttc tcaactgctc ttatctagga tttgcgttaa
    51721 agttttggta agatagtttt ggagggaaaa agatggataa aaagcgttct ttatacagta
    51781 tgcagcagga agtggatgaa tatatccagc aattcaaggt ggggtatttc tctccattag
    51841 ctcagatggc tcgattaact gaagaagtag gtgaattggc aagagaagtc aaccacactt
    51901 atggagaaaa aagcaaaaag gcttctgaac cagttaactc ggtagcagaa gaacttggtg
    51961 atgttttatt cgttacgatg atcatggcta attcattgaa tatcgactta actgaagttt
    52021 ttgaaaaaaa catggaaaaa ttcaatcaaa gagaccataa tcgctttgag cgtaaggacg
    52081 agtaaacaag atgaagtggt tctggccttg aagactctga aacggacttg tcaaacagtc
    52141 accatgcaac tgagtcttta tctcagtaca agaaacacgc aggaaaggtt ggaaaaatga
    52201 aattaaaaca attacctctg gaataccaaa aggcaattcc agttctgaaa aaattagaga
    52261 atgcaggata tgaagcttat tttgtaggtg gaagtgtacg tgatatcttg ctgaaccagc
    52321 caatccatga tgtggatatc gcaacaagcg catttccaga agaaatcaaa cagctttttc
    52381 caaaaacgat agatattggg atcgaacatg gaactgtgtt ggtattagaa aatgatgaac
    52441 aatatgagat caccacattt cggacggaat caacttatca ggactaccgc agaccagatc
    52501 atgtcgaatt cgttcgttcg ttggcagaag atttgaaaag aagagatttt acgatcaatg
    52561 cgtttgcttt gaaagaagat ggagaaatca tcgatttgtt cgatggtctg caagatttag
    52621 aagaacagat cttgcgagct gtaggcaatc ctcatgagcg gttccatgaa gatgccttac
    52681 gaatgatgcg cgggttgcgt tttgtcagtc aactagggtt caaattagag gaagaaacct
    52741 tctacgccat caaagaaaac cacgagctat taggtaaaat atctgtagaa cgtataaatg
    52801 tggaattcat caagatgctc ttgggaaatg aacgggccgc gggaatccat gcatttattg
    52861 aaacagagtg ctacatttgc tgtcccagtt tgaaagaaga aggcgaagca cttttacgtt
    52921 ttgctgaatt accatccgtc ccattgaaag aagagagcca agtatggaca ttattgatca
    52981 gccaactggg tctaaaagaa aatgagattc gttccttttt gaaatcgtgg aagtgttcta
    53041 accaaatgat taaagacgtt caagcacttg tccaaggact acgacaacga gaaactggag
    53101 ctttggaacc attcgaattg tacttcttag gcaaaaaaca tgcactgcaa gtagaagaat
    53161 tgatgatcta ttttgacgaa acacctcaga tggatgccgt aggagaatcc tatgatcgtt
    53221 tacctatcaa gtcattaagc gaattagcag tagatggtaa aatcttgcta gaagaaactg
    53281 gaaaaaaacc tggtaagtgg gttagtgaag ctttgcaatt agctgaaaaa gccgtcgtag
    53341 aacaaagaat aaaaaatgat aaaaaacagg ttttggattt tttatcgaaa gaaaaattga
    53401 tttaaaaaac actagactgt atctgctcag ctttgttggc tacttaaagt gggcagatac
    53461 gtcattagaa gaaaaaacat aagatgtgac cacttacata aatttgtgct aaactgaggt
    53521 agtacaagaa taaattacat cataaaggag tctttttaat gagtaaagaa atgacagcgc
    53581 taaaatttta ttttagaaat ggagaaacct ggacgatcaa ccgccgtcat atcggcgatc
    53641 tttggatcaa acaaatcaca acaagttttg gacgaatcaa tggcagtgaa tttgttgaaa
    53701 tccatccgtg tgctggattt aaaatcgaaa tcttccatga aggggacgca gttgcgacac
    53761 atgatatcaa cctaggcgga ctggaaatgg gcatgtttaa tcgcgcattg aaatacgaag
    53821 atatcgagcg aatggaaatc ctttaccgaa atggcacacc tgatcttgtg tacttcccat
    53881 atctagataa aggaacagaa ggattagaca atcaatatca atcaacaaaa atcagcgaaa
    53941 aaacaggtaa cttgtatatc gtgatcaatc cagatcaacg tgtagaagat gtatacgggg
    54001 aatttttcga ataaatcgat ttttacgcaa aaatgaagct gtgaaagaga tgtgtcttat
    54061 tactactgat aggctgtctc ttccacaccg tttattcaga ataagggact gtgacaagat
    54121 ttttgtcgca gccccatttt tttgttgtga taaaagaaca agaaaggcag gaatggaaaa
    54181 gtaaacattc ttttgtcaga aacttttatc tttcttaagt tttacttgat atctgatact
    54241 atttggaata gaatgaggcg ttgaaaaatt tatggaaatt tctaactagc aataaacgat
    54301 gaaacaatga aatatttttc atccaaaaag aactttgcta taatgatgga agtttgtgta
    54361 taggagatct ggaaaatgag agagagtttt gaacaacaaa aaaaactgtt gcatgatcgc
    54421 tatggcgccc tttcgatgga tgaccgccgt caaatacttt gtaagttgcg taaaagaaat
    54481 atattgatgt atcgtcagtt ggaacgtctg aaacatgatc tgcttcgttt ggagtcaaaa
    54541 cgtgtacagt gtgaattaga gggtaaccaa acacaggttg aagtagtcga aaccaaaatt
    54601 ttaaagaaaa aagaacaatt tttaaaaatg cttacacaaa ataaaaaata aaggggatgg
    54661 acgatggaat ttgctgagtt agttattgta tttgcagtaa cgatcacctt atcgaacata
    54721 gctagccgca ttttgccaat gattccagct ccactgatcc aaattttcct tggagtggta
    54781 ttaggtctga cagagtgggg acaatcaatc gattttgaac ctgaattgtt cttagttatg
    54841 attattgcac cattgttatt tagagaagga gaaaaagcag atatttcttc gattctcaaa
    54901 aatttcggga caattttgtt cttggcattt ggaggagtca ttttgaccct tgtcggggta
    54961 ggtgcgacgt tatcattcct gttgccaagt gtcccacttg ctgcctgctt tgcttttgga
    55021 gcagcgttag gtccgacaga tgcggtagca gtcagttctc tttctggacg agtgaatatc
    55081 cctaaaaagg cgatgcatat tttggaagga gaaggtcttt tgaatgatgc atctggtgtt
    55141 actgccttcc agtttgctct tggtgcgctg atcaccggat ctttttcagc agtaaacgcg
    55201 gggatgagtc tagtagtttc tagtattggg ggagctttga tcggcttttt gcttgtctgg
    55261 ttcaaacaaa aaataattca tttgatcgaa aaagcatcag cacaagatgt cacagggtat
    55321 ctgctgatcg aacttttgct tccttttcta gcctatgtat tggcagaggc atttgatgta
    55381 tctggaatca ttgctgcagt ggcagcaggt attctccaag cttctggttt taggaaaatc
    55441 tctgtgtttg atgcagaatt gtcgagcttg tcccacagta catggacaac tattgctttt
    55501 acactgaatg cattagtatt tatattttta ggaatcgaat tgacgcaagt gttctcgcca
    55561 gtatggggag acggtttata tccaaacggt cttttattag cgattatcgt attaatctct
    55621 gtcatgcttt ttgtgatcag attcatttct atcagtcttt tttatgtatt caaagatggc
    55681 agtaaaaagt tcaaaaaaca gttgaacgag atcttgatct taacatttgg cggtgtaaag
    55741 ggaacagtca gtttggctac gatttttatt ttgccatttt caatcaataa tatgatgttt
    55801 taccagcggt ctttgctttt gtttctgacg gcgggtgtca tcttagtgac tttggtcata
    55861 gggatcattg tcttgcctat gctgacggaa acagaggaag cgaaaagcac ggatttgaat
    55921 gctttgatga ttttagaaga ggtcgttgaa gttttgcgaa aagaaataaa ggaaattgat
    55981 cgtaatacaa aagaattttt agccactgaa gcagtgatag aaaattatca agaacggata
    56041 cgtgatctgt acttggaaga tttaaccgat gatgaaaagc aagaagtaca agaaatacaa
    56101 gcactgattt tgtcgatcga acgggatgga ttggatgaaa gttatcgttc gggcaagctt
    56161 tcttctaatg gttatcgttt ttactcccgt tttctttctc gattcgaaca ttctatcaca
    56221 agccagattt tgtcttttat cggcttttgg ttcattgttg tccgtaggtt aatgcgaatc
    56281 gttctccatc cgaaaatgtt ttggcaaaga agacatgctg atcgtcagac atttattagt
    56341 gatgaagata tccaagaaat cagagagaca tatcaaaaaa atactcagtt gattattgaa
    56401 agtttagata acttgactga tatttatgat gaaacgatgg ttcaattttt tatccagcaa
    56461 cgcaaacttg aaggaataaa aatgaactcg gggaatttga tttcttcgtg gatgatccag
    56521 caagatagtc tgtttacaaa aaaaatgcta agaggttatt atcttgaaag aaaaatcatt
    56581 gatgaatacg aagttgctga gaaaatcacg acgttttctg cgaacagcta tcgcaggaat
    56641 atcaatttgt tagaatctta tacgatgaac aaaccatctg ataacttttc tttccgattt
    56701 gcgtttcgag caaagtcaaa aaaacgagtc caataaaata aaaaggtaaa aattttcaag
    56761 ttttataaaa aacaaaacat atcagaacag gatcgaatcg gtcctgttct ttttttgaga
    56821 acacaaaaag aacaaatacc aaaaaaattt tcctgaagtt cactattttt atgatacaat
    56881 atccaagata aggagggaac atgttgaaag aattaaaagt aactgacctc aaaaaaactt
    56941 atggtgaaaa agatttgttt gaccagattt cttttttggt ccacgaaaaa gaccgtatcg
    57001 ggttgattgg gacgaacggg acgggtaaaa caagtctctt aaatattatt gccggtatcg
    57061 atagcggcga cggtgatcgg caaacagtgt tttatccaac tgattaccgt attggttatc
    57121 tttctcaagc agctgaattt tccgatgaat taactgttct ccaagcagtc tttcaaggaa
    57181 acagcccctt gatccaaact gttcgagcat atgaggaagc attgatcgaa ctaggggaaa
    57241 acggagaaga ccctgatgtg caaaaacgtt atgctaaagc agaagaacaa atgaataaag
    57301 aagatgcttg gactacagat accaacgcaa agattatttt gcaaaaatta ggaatcagtg
    57361 aattagataa aaaaatcagt actttatcag gtggtcagaa aaaacgagtt agtctggcgc
    57421 aagtgttgat tgatgaaccc gatttactat tactagacga accaacaaac catttagatt
    57481 atgaagcgat cgagtggttg gaaaactatt tgaaacaata ccgtggcgca ctattgatgg
    57541 ttacccacga tcgttatttt ctagatagag tagcaaaccg aatcttcgaa ctttcatttg
    57601 gaaaattata cgagtataaa ggaaattatg aagcttacgt cttagaaaaa gcagaacgtg
    57661 atcgtgtaga agtagaacaa gaagaaaagc gcaagcggct ttataaacag gaattagctt
    57721 ggatgagggc tggcgtacag gcacgtggca ccaagcagca agcacggatc aaccgtttcg
    57781 aagatctaaa ggagaacttg taccaagtaa accaagaaga tgatttagag ctgaacctag
    57841 cgacacaacg tttagggaaa aaagtactgg aaatcaaaga tggcagttac cgtataaatg
    57901 accaaacact gctagaacat ttagatttac tgattcaatc tcgggaaaga ctaggtatta
    57961 ctggtaaaaa tggtgcggga aaatcgacat tgcttaatat tctagctggc agaattcccc
    58021 tggatagcgg tacaatgtct atcggtgaaa cggttcatct tgcgtattat acacaagaaa
    58081 atgaagaaat ggcaccagat aaacggatga ttgcttactt acaagaagct gctgaagaag
    58141 caaaaacagc agatggcagt caaatcggag tagcagaatt acttgaacga tttttatttc
    58201 caagatttat gcatgggaca ctgataggca aactttcagg cggagaaaaa cgccggttat
    58261 ttttgttgaa actgctgatc cagcaaccta atgttttatt attggatgaa ccgaccaatg
    58321 atttggacat agcaacattg acgattttgg aagattattt tagaagtttt ccaggtgctg
    58381 tgatcactgt ttcccatgac cgttatttct tggacaaggt agcagataag ttattagtat
    58441 tccaaggaaa cggaaaacaa gaactttatt acggaaacat gtccagttat ttactgaagc
    58501 aaaaagagac ccagcagcct gctgaaaaag cgaaaccaaa aatacagagc aaggaacctg
    58561 ctgaaaagaa gaaattatct tacatggaac aaaaagaatg ggaaacgatt gaagatgaga
    58621 ttgcagaact tgaagaaaaa atctcattgc tccaagaaga gatgaatcat caaggagata
    58681 atttcactcg attacaagaa ttgcaaaacg acgtatctga aacagaagca caacttgaag
    58741 aaaaaatggc acggtgggaa tacttgagtg aatgggtaga agattaggag gaaaaaggat
    58801 ggaacaagcg tatcttgact taggaagaaa attgttggaa gaagggcatc gtaaagaaga
    58861 cagaacaggc acaggcacat taagcttatt cggataccaa atgcggtttg atctgcaaaa
    58921 agggtttcct ttgttaacaa cgaaacgagt accttttgga ttgatcaaaa gcgaattgct
    58981 ttggttttta aaaggagata cgaatatccg ctatctatta caaaataaaa accatatttg
    59041 ggatgaatgg gcatttgaac gctacatcaa aagtccagac tataatggac cagatatgac
    59101 tgattttggc catagatgtt tgacagatcc tgaattcaat gaagaatata aaaagcagag
    59161 caagcttttt tgcgagaaga tcctaaccga tgattccttt gctgaaacat acggcgatct
    59221 tggacacatc tacggctatc aatggcgtca ctgggaaaca aaagacggtg gctttatcga
    59281 tcaaatcaaa gaagtgatcg aagcaatcaa aaagactcct gattctagaa gattgatcgt
    59341 ttctgcatgg aatccggaag atgttcctag catggctttg cctccttgtc atacgatgtt
    59401 tcaattttat gttcaagagg gacggctaag ctgccaattg tatcaacgca gtggggatgt
    59461 gtttctaggc gttccgttca acattgcaag ttatgcgttg ctgactcacc taattgcaca
    59521 tgaaacaggt ttagcggttg gcgaatttgt tcacacatta ggagacgctc atctttatat
    59581 caatcatatc gaacaaatga aagaacaatt gagccgagaa atacgcgcat ttccgacttt
    59641 agttttgaat caggaaaagc agtcagtatt tgattttgag atggaagata tccaattaga
    59701 aggatatgac ccacatccgg cgatcaaagc tcctatcgct gtttagaatc agaaaggatg
    59761 agaaaatgtt agctgcaatt tgggcacagg atgaaaacgg attgattgga aaagaagacc
    59821 gtcttccttg gcgtttgcca aatgatctga aattcttcaa acaaatgaca gaagcaaata
    59881 cactagtgat gggacgaaaa actttcgaag ggatgggtag ccgtccgttg ccgaatcgtc
    59941 agacgattgt tttgacgaga gattcttcct ataaagcaga aggcgtgcat gtcatgcata
    60001 gtgtggaaga cgtgcttgct ctggaaaaag aaacagacgg tatctttttc atcgctggag
    60061 ggtcagctgt ttatcaagaa tttctgccat tttgtacgat attataccgt acagtcatcc
    60121 atcatgtatt cgatggagat gcttattttc cacctgttga ctggtctgat tggtcactga
    60181 tcaatactag tcaaggagaa atagatgaaa aaaatcgtta tccgcatcaa tttgaaacgt
    60241 atcagcgtaa tgagaatcct gtaaaaagcg ggacaggcga attgacgata taaaaaagct
    60301 atggatagac tagctgttat ttagagctgt cccatccata gctttatttt tttttattaa
    60361 gtaaagaata aaacagagaa gtacataaaa cctgcaccta acataacaaa caaatgccaa
    60421 acaacatgca tatagcggat agaattcaag ctataaaaga atgcgcctat cgtgtaagaa
    60481 agcccgcctg ctaccatcaa aataacacca gtcattccaa gagagtgata aagaggaaca
    60541 gcagccacga cacagagcca ccccataaaa atatagatga tcgtagatac ttttgatact
    60601 ctctcccgtt tatgcaacgt caacgcttta tatataatgc caagaatcgc aaacaaccag
    60661 attaatacaa ataaagtcca acctagccat cctcggatac tcagcaaaca aaaaggagta
    60721 taacttcctg caatcaaaag aaaaatcgaa ctatgatcga atacttggaa cacctttttt
    60781 gcttttgtaa aaatcaatga atgaaacaaa gtagacgtta aaaataaaag aatcatcatc
    60841 gatccataga tagcataaga gacaatatgg agggaggaat gcaagtgggc accttttact
    60901 aaaagaacca ctagtcccgc gatactcaat ccagtcccaa ttccatgggt gactgcatta
    60961 aacacttcat ttaatatttc atacgttcga ttaaatttcg ttttttccat gaaaacggct
    61021 cctttactag gtgtaattaa tgaaaaatca ttatttgtct gttatactaa aaatagaaat
    61081 tgtcttacat gtagtttaac atgaataagg catcttgtta aagaaagaga gagagaaaat
    61141 aatgacaaat gtaaaaatcg taacagattc ttcatgtacg atggaaaaaa atgtacgcga
    61201 tgctttaggc attcgtgtca tgccgctatc catcatgatc gacggaacag tatatcccga
    61261 tgatgaccaa ctagacggcg aaagatttat ggaaatgatg gcaaaagcaa aaaatctgcc
    61321 caaaacaagc caaccaccga ttggagaatt tatctcgatg tatgatgagc taggagaaga
    61381 cggcagtgaa gtgatttcga tccatatgac aaaaggcttg agtggaacag tagaagcagc
    61441 aagacaagcc agtaatctaa caaaaacgaa agtaacggtt atcgacagtg ataccactga
    61501 ccaaggatta tcttttcagg taattcgagc agctgaatta gcaaaagaag gtaaaacagt
    61561 agaggaaatc cttgaagaag tcaaaaaagt acaagacaat acaaaattat acatcggaat
    61621 atccacacta gataacttgg taaaaggtgg aagaatcagt cgaacaactg gtttgctgtc
    61681 tagtgttttg aacatacgcg tggtgatgaa tttcgcccat tctgaattaa tccctgtaac
    61741 taaggggcga ggaaagaaaa cgttcgataa atggtttaat aatttgaaaa atgaactgaa
    61801 agaattgcca aatgtgcgac aaatcggtat ttcacatgcg gatgcaaaag aattggcgca
    61861 agaattcaaa gagggtttgc aagaattatt cccggacatg catatccctg tactgcatac
    61921 gaatccggtt atcgctacgc atactggtaa agacgcgttt gcaatcatgt attatgtaga
    61981 ttagtcgaaa agaggataag ccctcagcct gaaaggcttg cagcttattc tctttttctt
    62041 tataaaatta ggaaaataat tgttttcttt tttcataaag actacctttt tgataaaatt
    62101 tttgataaca ttagaaccaa tcgaatacaa gaggtgaaaa aatgaaatta acgaaacgac
    62161 atctgatcct cgttttgttc ccattattaa ttgcgatcat catctatgca ggtttagctg
    62221 cttctatacc gaaagctggc ccactaatga aaccagtaac tactgtgaga gaagatccaa
    62281 ataaaaaaga aaaacttcac tacatagcta tcggagattc gctgactgaa ggagtaggag
    62341 atcaaaccaa gcaaggagga ttcgttcccc ttgtcgcaaa tgatctaaaa gaccgttata
    62401 atttgaccgc ggttgaaaca gaaaactatg gtgtaaatgg tgaacgaagt gaccagatct
    62461 taaagcgagt aaaaacaaaa gaagaaattc gaaacaatat caaaacagct gattttatca
    62521 cactgactgt tggcggtaat gatttgatga aagttatcca aaataattta ttcgggttaa
    62581 cggtcaattc ctttaaaaag ccactgaaaa actatcagga aaatgtcaca gaactattgg
    62641 aagaatttcg atccctcaat aaaaccgcac ctatttacat tttaggcatc tacaatccat
    62701 tttatttgaa ctttcctgag atcactgaca tgcagacaat tgttaacaat tggaacaaag
    62761 gaacagaaac ggtgacaaaa aaaatgccga actgctactt tatcccaatc aatgatttgc
    62821 tttatcaagg attgaatcag gaagtaggtg tcacagaaga aggaacagat caaacaacta
    62881 gcacgacaga aaatctaaat ggcatcaaaa ataatgtgct ctatgaagaa gatcatttcc
    62941 atccaaataa tttaggttat caattgatgg caaatgcagt gagagatcag ctgatcgaga
    63001 cacaaaacca atggctagag aaggaggatg atcaataaac atgaaaacaa gatctgacgt
    63061 atcttcaaac aaaacaaaga aaacaaatta ctggaaattc gccttcctta tccttcttgg
    63121 ggtagtactt ggttcgaccg tatttttagg cagccgtatt tttgctaatc gggaaccaga
    63181 actcccagaa ataccagctc ttacggaaag acaaggagat cctgtcttaa cgatcaattc
    63241 aaataaagaa aaagtcaatc aaatcatcag ctttttcctt agtgagtatc aaaaagatag
    63301 tgatattgaa tataaatttt atttggaaaa tgaagcacta ctcaatggta ctttcgaagt
    63361 actaggtttt cctatcgatt tctatttata ttttgatccg tatgtgatgg aaaacggaaa
    63421 tgtccaacta aaagctagaa gtctttctat cggaacattg agtttgccaa tcaaagatgt
    63481 gatgaatatg atcaagagaa actataaatt accagattgg atcgaagtca atacagatga
    63541 tctgactatc atgcttaggt tggatcaatt ccgaatgcaa aacgggatgt atattaaagc
    63601 agataaaatc gacttagtaa atgatgacat tcggtttagt ctatatttgc caaaagatac
    63661 ctctgatgct tcaaacaact caaataccaa caaaactagc accagcagta ctgaaagcaa
    63721 gacaaaagaa aataaaaaat catcggatga gtagtattag agggggaatc ataatggaac
    63781 gagcaatatt tgcaggaggc tgtttctggt gtatgatcca gcctttcgac acgcttcctg
    63841 gtatccatac agtgatgtca ggatatactg gagggcatgt accagatccg acttatgaac
    63901 aagtaaaaag ccaaacgact ggacatacag aagcagtgga gattatctat gatccaacat
    63961 tgatttcata tgaacaatta gtagaacttt actggcagca aactgatcca actgacgctt
    64021 tcggacaatt cgaggatcgc ggtgacaatt atcgcccggt gatcttttat ttgacagaag
    64081 aacagcggat cattgctgaa aaaagtaaga aacagttagc tgaaagtgga cgtttcgaac
    64141 agccaatcgt tacaaaaatc gaaccagccc aaccatttta tctagcagaa gaagaccatc
    64201 aagagtatta taaaaagcat cctgaaaatt ttaaaagaaa ccatgcacgc cgggctgcct
    64261 ttatcgaaga aaattggagg aacgaagggt gaatcgaagc ttttttcatt atttaatgac
    64321 actgcgaggc ggtggcacac atgatgcttt atctgttttc gctacagaag ccggtaaaga
    64381 catccaattt cctaagcaca gctctagcta cgaagaaatt tctaattatc tggaactgaa
    64441 tgtcgactat ttgccgtcca tggatatctt tgacgaagca tgggaaaaat atttagaaaa
    64501 taatcatgac atataagaga tagttttgta ctttatgatc aaaaaagttt tttgtccaat
    64561 agcctaattg aaagaattat ttttatttca gctatctagt cgcatttttt tgatattttt
    64621 cttataataa agaaagaatg aaaaaacgag ggatggattg atagagattg acaaaaaaac
    64681 aacgctatat taatcgcttc tggcttgtat tcaaatactt acttgtttct gtattccttg
    64741 cgttcatgtt gcggggattt ttattcatcc cggtaccagt ggaaggcaat tcaatggaaa
    64801 acgtgttgaa gcaaggtgat atggttgtga tggaaaaatt ttcggagatc agacgatttg
    64861 atattgttgt ttttcaatta gcagatggca cgatttatat caaacgagta atcggtcttc
    64921 caggagaaaa tgtcagctac caaaatgatc aattgaagat caatgggaaa gtagttaagg
    64981 aaccttatct aactaaaaac ctgaaatcag atcatgcaaa tgcatcctat acgacggact
    65041 ttacactaca agagctaacg ggacaatcca agcttccgga agataattat tttgtacttg
    65101 gagataatcg aagagtttca aaagatagtc gttcgtttgg cacgatcaat aaaactgata
    65161 ttctaggtaa agcaagattt gtctattatc cacttgatga aataaaatgg atccagtgag
    65221 aaacaataaa gcgtgcaatc tgttgagact gcacgcttta ttgtttaatc caaaatcagt
    65281 ttactacctt agtacgtaaa atcaaacagc tcgtttaaac acttttctag cctctaaagt
    65341 tttgataaat gaataaacaa ccattatttg aatagggatt tggatcatat tcctgatgac
    65401 tctacctaga aaaatcactt tgaaatctgc accaaacaaa acagacatca gccaagaatt
    65461 gataaaaagg ctgactggga tcataatcaa taattgggca gcgatgacgg aaggcaggtt
    65521 tatcttttta tgatataaaa ataagccatt aataaatcca ccaaggaaag ccgtgataag
    65581 aaaagcagct tgaaacgttc ctgaaccaaa tatcgtgaaa tttaaagtgt tcgacaacat
    65641 ttcaagcaaa ccagcccaga tcggtccata tagataaccc ataagcgcca tacttaaaaa
    65701 tccgaatgtg atttgaaaat aagcaggacc aatcgctatc ttgtataaga tgacatcaag
    65761 ggctaataaa agagcagagg tcgacaacaa tcttgcattc atttcgggca atctaaaaac
    65821 gtcttttgca atcaaagtgt tcaaaatatt ctctcctttg tcagttaata ataaaaggat
    65881 accataaaat caccaatgtg tcatgacaca ttggtgattt acatacactg gcatctaaca
    65941 attaaaaaaa gggtgagaag actgctttta taaactgtaa aaaagagatt gtacgaatga
    66001 aaaaaataga ggcggagaat acttatcgta tcatccgcct ttgttttttt gttataaaaa
    66061 acgtcagatt agttatctgc ttacatcttc atccatacgg gttctaatgt atttccgtct
    66121 agatcttgga cttctaatga aaacatttct tcttcaggca ttcccatatc tacttcgtgg
    66181 aaagtaccac cattttcttt tgcaatttga gcaaattttt ttacttcatc cgcgttttca
    66241 acactaaacg aaatcaaagc accacttgtt tttttattat cagctatttc tttatctttt
    66301 ataaattttt tataaaaatc atgagagaga agcattaccc aaaaagtgtc atcccatacc
    66361 attgaaccag cttcttcagt agaaaattct tcattttttt taaaacccag cttttcataa
    66421 aaagcaacgg aacgattgac atcagcaaca ggaaaattaa caaaaaccat actattcatt
    66481 tgtttcgtct cctttctgtt ttgttcgtct atcatctctt atttaggaaa cgttgtcaaa
    66541 aatttagatt catatataga aaccaaaata aaaatttaca tcatcaaaaa agtgaagatg
    66601 tgatagaatg aggactggtt cactttcact taactaatag atggaatttc tttataataa
    66661 aaaagtgaat ttatattgaa aaagaaaaaa aacaagtaaa gccggggaat attccggtat
    66721 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    66781 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    66841 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    66901 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    66961 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    67021 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    67081 ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg ttgggaaatc
    67141 tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata agcctggcgt
    67201 aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag acacaccagg
    67261 gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc tgacaggcgc
    67321 gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag acttttttgc
    67381 ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc aagaagaaaa
    67441 attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag aagactatga
    67501 tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac gatacacact
    67561 ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa agtatcaaag
    67621 aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta agaaatgatc
    67681 cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa aaggaagcat
    67741 taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac gcacaaggtc
    67801 accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga cctgtcgtgg
    67861 cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac tccaaacaat
    67921 tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc ctggcaatcg
    67981 ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa gcaagtaaat
    68041 tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg ttgatcgatg
    68101 cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat gcacgatctg
    68161 tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg atgaaagaat
    68221 atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga acaaaggaac
    68281 acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt tttgcacctg
    68341 taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga aagagagacg
    68401 aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc ttatacaaaa
    68461 ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta tccttataaa
    68521 gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg ggagctgttt
    68581 cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa acagtcgttt
    68641 atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta tccgccaatt
    68701 gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag cgttgttggt
    68761 ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa accagtgata
    68821 gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata cggtcaccaa
    68881 gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat agagcaagtc
    68941 tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct tcttttgagt
    69001 gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa tcggattatc
    69061 gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg ctctctgata
    69121 acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg aaatatttta
    69181 acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg cacggtttcg
    69241 ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt gcttttcttg
    69301 acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc ttttaatagt
    69361 aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt tagtgattgt
    69421 agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact ataaagtaat
    69481 ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg attttgaaaa
    69541 caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca aaagcctgaa
    69601 agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata gagaaggaga
    69661 agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa aaaatcgggt
    69721 ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac caagaacgat
    69781 cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa tcgttggtta
    69841 ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag gacgtgtcca
    69901 atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat ttgttccaga
    69961 agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca aagcaaattt
    70021 ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa aagaagtcac
    70081 tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag agcgcaaaag
    70141 aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc gtaagttaaa
    70201 ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa tcactttggg
    70261 taaacaagga acagtcggct tgattacata catgcgtact gattctaccc ggattgccga
    70321 tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag aattttctag
    70381 acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg aagctgtgcg
    70441 tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata aagatcaatt
    70501 gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac cagctatttt
    70561 agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga acggttcaaa
    70621 aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg gcaaagaaga
    70681 gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg ttgatattga
    70741 accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt tgattcgtgc
    70801 actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg atacgatcca
    70861 aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac taggagaaat
    70921 tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt tcacagcaga
    70981 aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca aagtggttga
    71041 tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa tcgaaaaaat
    71101 tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc cgatggtgat
    71161 aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt gtcggaatac
    71221 gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag gacaagtcat
    71281 tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc cagaatgtga
    71341 attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg gatatctggt
    71401 cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt acgaagaaga
    71461 catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt gttggagcag
    71521 ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct gtccgtttat
    71581 atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt gctgaactag
    71641 tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta ttgaaagaag
    71701 aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca gtgccagctg
    71761 gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga aaagtcaaag
    71821 agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa ggaatcaccg
    71881 tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa gcattcaatg
    71941 gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa gctacgatcg
    72001 atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct tacttgaact
    72061 gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat gccgaagtgg
    72121 cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca attgaagtaa
    72181 tggcacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt ggattggaag
    72241 atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac aatgctgcag
    72301 cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag caaaaacgtg
    72361 ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt gtgatgcacc
    72421 gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca acgaaacgcg
    72481 aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa agtgcagcga
    72541 gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa ccagtcgagt
    72601 ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg gaaggaaaac
    72661 atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag cgcattcgag
    72721 acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat gaggcaataa
    72781 aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg aagagggtga
    72841 gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa caaaatgtga
    72901 ggaattgcgc caattgtgaa caaacttaga aatattggtt aaattctgac aatttatttg
    72961 tctttttata aacgctgtgc taaattattc tctgggacaa aaggaaggtg agaaaatgac
    73021 agaagccacg tgggaacaaa aatttttgcg ttatttgatt gtcgaaagag gatattcaga
    73081 aaaaacgaaa gaagcatatg aagaagacat tctccatttc aaacattttt tggaggaatc
    73141 tggagacgct gatctgctga aggcggaata ttttacggtt cgtgtctatt tgagtgcatt
    73201 agctgatcat cgtcctagct atagcagaaa ttctatcagt cgcaagatag ccagcctacg
    73261 ttcgttttat cagtatcttc tcaaagaaga agtgataaaa gaaaatccat tttcttacgt
    73321 tcatctcaaa aagaaaaatt tgagactgcc acgttttttt tatgaaaatg aaatgcaagc
    73381 actttttgac agcgtagcag gagatagtcc tttggatttg aggaaccgcg ctttactgga
    73441 agtcctttac gggtcaggca tccgtttaag tgagtgtagc agtttgtcgg tatcagacat
    73501 tgattttgat tcagaggtca tgttgatcca tggtaaaggg aacaaagaga gatatgctcc
    73561 tctaggttct tttgctcaag atgctctgca agaatatttc agggaaggcc gccaggtatt
    73621 gatgacaaaa tatcacgaag agcatgatat cgtttttgtg aatcatcatg gaaaaccaat
    73681 cacgcctact ggaattgaat atgtcttgaa tcaaatgatc aaaaaaagca gtttggatag
    73741 tgatatccat cctcacatgc tgcgccatac atttgctact catttattaa ataatggggc
    73801 agatttgcgg acagtccaag aattgctagg acatgccaat ttatcgacta cccagatcta
    73861 tgcccatgta acaaaagaaa gtttacaaaa aaactatcgt tctttccatc caagagcgta
    73921 aaaataagga aaagaacaaa tttaggagga aacaaacatg gtcgaatcac catttcattc
    73981 aaccactatc tgtgccgtcg aaaaagacgg gaaatttgct atggctggag atggccaagt
    74041 aacaatgggt gaatctgttg tcatgaaagg cactgcaaag aaagtacgac gtatctacaa
    74101 tggagaagtt gttgtaggtt tcgccggaag tgttgcagat gcgtttactt tagaagaaaa
    74161 atttgaaggc aaactaaacg aatataacgg gaatctacaa cgcgcagctg tcgaattagc
    74221 tcaagaatgg cggacacagc aatctatgca aaaacttgaa gcgatgctga tcgtaatgaa
    74281 tgataaagaa atgcttcttg tttcaggtac aggagaagtt atcacaccag atgatggtat
    74341 cttagctatc ggatcaggag ggaattttgc gttggctgca gcccgagcaa tgaaaaacta
    74401 tgctcaaaac gacatgagtg cgaaagaaat tgcagaaaat gcgttaaata ttgccgcaga
    74461 tatctgtatc tttactaatc ataatattat cgtagaagaa ctgtaagagg tgagtagata
    74521 tgtatgaatt aaaacaaaca ccaagacaaa tcgtaagtga attagatgaa tatatcgtag
    74581 gacagcacgc agcaaaaaaa tctgttgccg ttgctttgcg taaccgctat cgccgtttgc
    74641 agttagatga aaaaatgcaa caagatatta caccaaaaaa tatgctgatg atcggaccta
    74701 caggggtcgg taaaacagaa atcgcacgac gtttggcaaa aatcgtcaat gcaccatttg
    74761 tcaaagtcga agcaacaaaa tttactgaag tcggttatgt cggaagagat gtagaatcaa
    74821 tggttcggga tttagtagaa aatgcgatcc aaatcgtaga aaaagagcag tacagccgtg
    74881 tatacacaag tgctaaaaaa aatgcagaaa aacgtttggt aaaaatcttg gtacctggta
    74941 tcaaaaaaga acagaaacaa tccactaatc aatttgaaca aatgatgaat ctttttaatg
    75001 ctagtcagca aaataccgct gaaccgcaag aagaagtgac agaagatatt cgaatcaatc
    75061 gccgtacagt cttggaacaa ctacaaaagg gtttactgga tagtcgtgaa gtaaccattg
    75121 aagttgaaga ccaaaagaaa cctgcaccaa tgatgaacaa tggattggag caaatgggga
    75181 tcgacctaaa tgaaactcta ggtgctttga caccgaagaa aaaagtggaa cggacggtaa
    75241 cagtcaaaga agctttagag ttattgatca aggaagaatc agcaaaatta gtcaaggatg
    75301 ctgatatcca tagtgaggca atcaaattag cggaagaaag tggaattatt tttatcgatg
    75361 aaatcgataa gatcacttct aaatcacagc aatctggaga agtatccaga gaaggcgtcc
    75421 aaagagacat attgccaatt gtcgaaggtt cacaagtaaa cacaaaatac gggatcatcc
    75481 aaacagatca cgtcctattc attgcttcag gagctttcca tttgtctaaa ccaagtgatc
    75541 taattccaga acttcaagga cgcttcccga tacgggtaga attagatgat ttgacagctg
    75601 aagattttgt gaagattctg accgaaccaa ataatgcttt agtaaaacaa tacgtcgcgt
    75661 tgatcggtac agaaaatgtg tcagttacgt ttacaaaaga agcaattgaa cggatcgctc
    75721 aaatcgcttt cgatgtcaac cgtgacacag ataatatcgg cgcacgcaga ctgcatacca
    75781 ttttggaaaa actactagaa gatctattat ttgaagcacc agatatgcaa atgggagaaa
    75841 taacgatcac agaagcatat gtggatgaca aacttggctc aattgcggca aatgaagatt
    75901 taagtcgcta tattttataa aaaatcggag gacgacaatg acagacttgc taacgaaaac
    75961 ccgcaagata aacacacttt tgcagcaaaa gaatactttt gacatgcaag cagatttgcc
    76021 ttacgataaa atggctgtca cactaggtgg tattcttgac agcaacacct atatcatagg
    76081 aagtgacgga gtattactag gttataatga acgtcacgat gtgaacaatg aacgaatcaa
    76141 aacaatgttt gttgagaaac aatttcctga atcttatact gatacagtgg cacagttgat
    76201 gaaaactgaa gctaatatcc caattactag tgatattact gcatttccgg tagagtcaag
    76261 agagaaatat ccatttggtc tgacgactgt cgttccgatc tttggagctg gcgaacgttt
    76321 gggtacgatt atcttatctc gtatggaaca atcgtttgca gatgacgatc tagtcttagc
    76381 agaatatgga gctacggttg tcggtatgca gatcctttat cagaagtctc gaagcatcga
    76441 agcagatgta cggagtgcaa cggctgtcca aatggcaatc aacacattat cttatagcga
    76501 attgaaggct gtacaagcta tctttgaagc attggatgga gatgaaggtc gtctgactgc
    76561 ttctaatatt gccgatagta tcggcatcac tcgttctgtg atcgtcaatg ctttacgaaa
    76621 attggaatca gctggaatca ttgaatctcg ttcgttaggc atgaagggaa cttatttaaa
    76681 agtattgaat tcccgtttta aagacgagtt agcaaaacac agttattaga agtaagggga
    76741 ctggggcaga tagaaatgtt tgttccagcc ttcccatttt aaaaagtaag tcgaagttgg
    76801 aggaatggca atgactgtta ttattcaaaa tgaccagctg atcgccgaaa tcgctgaaca
    76861 cggtgcggaa ttgatcagtc tgaaatcaaa agaacatggt ttagagtata tctggcaagg
    76921 tgatccagcg tattggggca gacatgcacc ggttttattc ccttttgttg gacgtttaaa
    76981 agatgatcag tatgtttatc aagggaaaac atatcaaatg gggcaacacg gatttgctcg
    77041 ggatatggat tttgaagtca ttgaacatgg acaagaaatg gctagtttca tcttaaggag
    77101 tacgccggag acattagaaa agtatccatt tgattttgaa ttagtgatca ggtatgaatt
    77161 aggaggagac ggcatcacgg ttcattatca agtggcaaat accggtgaaa aagaaatgtt
    77221 cttttctatc ggtggacatc ctgctttcaa tgtacctctt gaagaaggat tgtcatttga
    77281 agatttctat ctggcatttt ctccattgaa atcaagatta cgcctaccat tgaaaggccc
    77341 attcatcgat atggatcaaa agacgttagg tcagacaaat acgaatctgg ctttgaatcg
    77401 tgaacttttt gagcaagatg ccttggtttt tgaaacaagg ggtctaaatg cgtacgccat
    77461 tcgaagtgaa aaatcttccc atagcgtaac tttaagctat aaagatatgc cttatgtagg
    77521 gatctggtct ccttatccaa aagaagcgcc tttcgtttgt atcgaaccgt ggtgcggaat
    77581 cgctgacacg gtgaacagta gtggaaactt gatggaaaaa gtagggatca atcaactagg
    77641 tgcccatgaa atcttcaaga caaaatattc catcacagtg aagtaagagg ttgtgaccga
    77701 gaagttagca gggaacaccg tttaccaagg tgtgtaaaaa agctatcctg taagtaataa
    77761 gggagtgtga catcgatttg tcacactccc gttttatctc tttggaatga aaaagtatca
    77821 ggattttttc ttgctgctat tcaaaccaaa cgggattcga ctttcagtat ggtttctgat
    77881 acgcttgata ttgtctttat gccgataaaa gataaaggaa gaaactaaaa aggcaatgat
    77941 cgtcagtaac caattgggct tagccaaaat cacaggagct acataaggaa ggacgatcgt
    78001 agataaagtg atcaatactg cactgatcat actgctcaaa ctcaccatac ttgtacaaaa
    78061 taaactaacg ataaagatga tacaagaata aacaaaaaat acaggattaa atcctaaaag
    78121 cattcctgca cttgtcgcaa cagcttttcc tcctttgaac ccagcaaaaa tcggaaatgt
    78181 atggccaaga atggcgcata ccccaaacca aagagggtta atcccagaaa ggtggaagat
    78241 catcggcaaa caagtagcca atgtaccttt taaaatatcc ataagcagga caacaatccc
    78301 ggctgttttg cctaatacac gaaatgtatt ggtcgttcca gtattaccgc tcccgtgttg
    78361 tcggatatct tttttgaaaa acaatttgcc aatccagaca ccggaaggaa tagaacctaa
    78421 aagatatgct aaaataagta ataagatcaa tttcattttt taccctcttt caagttgaaa
    78481 actatccttt attttagcat gaataggtaa caggaacaat tgaaaaaatg aaagatacaa
    78541 gtataataga tggaataaaa agaaaagcaa ggggtggcag aaatgtctgt aaaaaatcca
    78601 acacaagaaa cgattttcaa ctatttggaa gaagcaaaaa atattgccgt cgtaggcttg
    78661 agcaataaac cagaacgaac aagttacatg gttgcacagg tattgcaaga caatggatat
    78721 aaaatcatac cagtaaatcc attattggct ggtgaagaaa ttctaggcga gaaagtctat
    78781 gcgaatttga cagaaatcga tgatccaatc gatatcgtag atgtatttag acggagtgaa
    78841 tttttacctg aaatagcagg tgattttttg aaaactgatg ctaaagtgtt ctgggcacaa
    78901 ttagggattg aaaacaaaga agcagctgag atgctaagaa aagcaggacg tacagatatc
    78961 gtaatggatc gttgtattaa gattgaactt ggtaagttga aagaaaacca aaaataaaaa
    79021 tgaccacaaa gaagagatga tcgatagagg ggaatgtcga aaaagcggtt aggagataat
    79081 taaaattgat ttctcgtcta ccctcttttt tttcacgacc ttttctagta tgataatcgt
    79141 ggtgcggttt tgccgcaaag tattattgaa ggagcgtttg ccttggcaaa aaaagtaaac
    79201 aacgaataca atgactcgtc catccaagta ttggaaggat tagaggcagt tagaaaaaga
    79261 ccagggatgt acattggatc cactgacagc cgaggcttgc atcatttagt ctatgaaatc
    79321 gtcgataatg cagttgacga agcattatca ggttatggca gtgagattga tgtgaccatc
    79381 catgaagaca atagtataac tgttgcagat agcggacgtg ggatgcctgt aggaatgcat
    79441 gcttccggaa taccaacagt tgaagtgatt tttactgtgc tgcatgctgg cggaaagttt
    79501 ggtcaaggag ggtacaaaac ttctggtgga ctgcacggtg taggagccag tgtggtaaat
    79561 gccttatcga aatggctaat tgtaacgatc gttagagatg gcgtagagta tcagcagaaa
    79621 tttaaaaacg gcggtaaacc tgacggtact ttgaaaaaga taggaaaaac aaaaaaagca
    79681 aacgggacga ctgtccattt tttaccagat gatacaatat tcagtacaac gaaattttca
    79741 tatgaaattt tagccgaacg gttaagagaa tctgcctttc ttctaaaagg cgttaaaatc
    79801 tctctttctg atcttcgtgg agaagaacca gtcaaggaaa tttttcatta cgaagaagga
    79861 atcaaagaat ttgttgatta tctgaatgaa gaaaaagata cattgacacc agttgtttat
    79921 ttttcaggag aaaaagaagg tatcgaagta gaggtcgctt atcaatacaa tgacggttat
    79981 tcagaaaatg ttttatcttt tgtcaataac gttcggacaa aagatggggg aacccatgaa
    80041 gctggtatga aagcggcgat gacgaaatct tataatgaat atgcgagaaa agttggtttg
    80101 ctgaaagaac gggacaagaa tctggaaggt agtgatttca gagaagggtt agctgctgta
    80161 ctttctatcc gtgtacctga aaatcttctg caatttgaag ggcaaacaaa agaaaaactt
    80221 ggtacgccag ttgctcgtac cgtagtagat aacgtcatca gtgaacaaat gggcttttat
    80281 ttgcaggaaa atagcgaaat gagccagatg ttggtccgta aagcaatcaa agccagagaa
    80341 gcgagagaag cagcacgtaa agccagagaa gaaagccgaa atgggaagaa gcgtaaaaaa
    80401 ggcgaatctc ttctttcagg aaaattgaca cccgcacaat cccgaaaccc taagaaaaat
    80461 gaattgtatt tagtcgaagg ggattctgct ggcggatctg ctaaacaagg aagagacaga
    80521 aagttccaag caattctacc tttacgagga aaagtcatca ataccgaaaa agctaaaatg
    80581 caagatatct tgaaaaatga agaaatcaat acgatgatct atacgattgg tgcaggagtc
    80641 ggtcctgagt tttctatcga agactgtaat tacgacaaag taatcatcat gaccgatgcg
    80701 gatacagacg gcgcccatat tcaagtatta ctgcttactt tcttttatcg ttatatgaaa
    80761 ccgctgattg aagctgggaa agtatatatc gcgttaccgc ctttatataa agtatccaaa
    80821 ggacaaggaa agaagcaagt cattgaatat gcgtggacag atgacgaatt ggcagcaatg
    80881 attaaaaaag tcggcaaagg atatatgctg cagcgatata aaggacttgg agagatgaat
    80941 gcggaacaat tgtgggaaac aacgatggat ccgacttccc gtacgttgat ccgcgtccgt
    81001 atcgatgatg ctgcgcaagc tgaacgtcga gtaaccacac tgatgggtga caaagtagaa
    81061 cctcgaagaa aatggatcga aaatcacgtg caatttacgc tcgaagaaga tggcagtatc
    81121 ttagataaaa aagaggatac tgaaatctct ccttcagttt ctaatgattt attagatgaa
    81181 gaacgagcag ataaaaatga aaacaatcag ttatttgaag tagaatagga ggtcacctga
    81241 tggaaaatcg acaagaagta caagaattaa ctttagaaga agtgatgggt gaccgcttcg
    81301 gacgttattc caaatatatt atccaagaac gtgcactgcc tgatatccgt gatggattga
    81361 agccagtgca acgccggata ttatttgcca tgaacaaaga tggcaatacg tatgacaaag
    81421 gattccgtaa atcagcaaaa tctgtcggaa atatcatggg gaattatcac cctcatggtg
    81481 accgcagtat ttatgaagcg atggtccgca tgagccaaga ctggaagttg cgggaagtac
    81541 tgatcgaaat gcacgggaat aacgggagta tggacggtga tccacctgct gcgatgcgtt
    81601 atactgaagc cagattatcc aagttaagtg gagagatgct agcagatatc gagaaagaaa
    81661 cagtcgatct cgtgtggaat tttgatgata cagaaaaaga accaacagtc cttccagctc
    81721 gatacccaaa ccttctcgtc aatggatcga caggtatatc tgctggatat gcaacagaaa
    81781 tcccgactca taacttagct gaagtgatcg atggcacaat ctatatgatc gatcatccac
    81841 aagcgagcct tgaaaaattg atggaatata ttcctggacc tgactttcca acaggaggga
    81901 tcttgcaagg aaaagatgaa atcaaaaaag cttatgaaac aggacgagga aaagttattc
    81961 ttcgttcgaa aacaaagata gaggcaatga agggtaataa acagcaaatc gtgatcacag
    82021 aaatcccata tgaagtaaat aaagcgacct tggtgaaaaa aatggatgag atccgtttga
    82081 ataagaaaat cgatggaata gctgaagtac gagatgaaag tgatagaaca ggtctgcaaa
    82141 ttgtcgtcga attgaaaaaa gacgccaatg ctcaaggaat tttgaattat ttgttcaaaa
    82201 acactgagct acagatcaat tacaatttca atatggtcgc tatcgaccat atgactccgc
    82261 atcaagttgg actgaaagac attttaagaa gttatatcga gcatcgaaag caagtcataa
    82321 caaaacgtag tcaattcgat ttagccaaag ctcaaaaaag acagcatatc gtagaaggat
    82381 tgatgaaagc tttatcgatt ctggatgaag taatcgcaac gattcgtgaa agtaaagaca
    82441 aaaaagacgc caaaaagaat ttagtcgacg tctttcaatt tacagaagaa caagcagaag
    82501 caattgtcac attgcaatta taccgtttga cgaacacgga tatcacagag cttcaaaagg
    82561 aatccgaaag cttgattgcg caaatcacag agttgaataa aatcctttca aatgacaaag
    82621 agcttttctc tgttatgaaa aaagaattgc gagaagtgaa aaaaaattat tcttccgctc
    82681 gtctaacgac aatcgaagac gaaatcgaag aaatcaaaat tgatacgcaa gtcttagtgg
    82741 cacaagaaga cgtaattgtc agtgtgacgc gagaaggcta tgtgaagcga acaagccttc
    82801 gttcttatag tgcttccaaa ccagaagaaa tcgggatgcg agaaggcgac tacttgctat
    82861 actcaggtga attgagtaca ttggaccatg ttcttctgat cacaaataaa gcaaatgtga
    82921 tctaccgccc tgtccatgaa ctacccgatt tgaaatggaa agatgctggt gagcacattt
    82981 ctcaaacaat ctccaatctg tctgtagacg aatcgatttt agctgttttc ccatatcaaa
    83041 aaattcaagc agagaaaaca tttgtattca tcagcaagaa tggattgatc aagcaaacac
    83101 gaatgacaga gttcgaacca tggcgcacct ataagagccg tccgctcagc tgtatgaagc
    83161 taaaggcgga agaagatgaa ctgattgctg tgtatctgaa agaagatcag ccaggcttag
    83221 atgttttctt agtaacgcat caaggaatgg gtttgcgcta tcctttaaca gatgttcccg
    83281 ttgttggagc aaaggcagct ggagtgaagt ctatgaattt gaaagatgga gataggatta
    83341 tcaacgggct gcttgtgtta gcagaaggtg atacgccgat cgtaatcgtt actcagcgag
    83401 gagctgttaa acgcatgctt gctcaagaaa tcagccaaac ttcacgtgcg aagcggggag
    83461 tgacggtcat gcgtgagctg aaaaaaaatc cgcaccgtat tatctatatg tcggaaggaa
    83521 gatcaaaaga aataaccttg atgaatcaaa aagggcagca gttaacgatt gacccaactg
    83581 atttccctat aggtgatcga acatcgaatg gatcatttgc gatggatgag aaaaaaggtg
    83641 gagaagtcat cgaagttatc gatgctcctg agattttcat cgagtcgtaa ctgttgtagt
    83701 attttaatga agagacgcca tctgtattaa tacaggtggc gtctcttttt cattcatttt
    83761 taataaatcc ttatacgttt gcaaaaaaag atgaaagtgt tcacaatgct taaatgttgg
    83821 tatgtcaacg ttgatttaaa tatatgtaaa taaaacataa aaattgttaa ataaaaaaca
    83881 agaaaaccct tgcaaagata gggtgctgtg ttatactaat cacgtaaaaa ctgttacata
    83941 aaacagaaat ttaggaggtc catacaatgg agcaatggaa tggatttaaa ggtaccaaat
    84001 ggaaagaagg cgtagacact agagacttta ttcaaaataa ctacactgaa tatcgcggtg
    84061 atgacagctt tttggaaggc ccaacagaag caacagaaaa attatgggat gaattgcaaa
    84121 agttaaatga tatccaattc gagcgtaacg gtgtctatga tatggacaca gaaatcgtat
    84181 caactattac ttcacacgat gcaggctatt tggataaaga tttggaaaaa atcgtcggtc
    84241 tacagacaga caaacctttg aaacaagcat tcatgccgtt cggcggaatc aatatggcta
    84301 acaatgcgct aaaaagcaat ggctatacac caaacgatga attgacacat attttcactg
    84361 actggcgcaa aacacataat caaggtgtat ttgacgctta tactgctgaa atgcgtgctg
    84421 ctcgtaaaaa caaaatcatt acagggcttc cagacgctta cggtcgcgga cgtatcatcg
    84481 gtgactatcg tcgtgtggca ttgtatggaa tcgactattt gatggaacaa aagaaaaaag
    84541 atcatgatat gactggttat catacaatga gtgaagaagt gattcgttta cgtgaagaaa
    84601 tcactgaaca atatcgtgca ttagcgcaaa tgaaagaaat ggctgcgaaa tatggctatg
    84661 atatttctaa accagctgca aatgcaaaag aagctgtcca atggctatac ttcggatatt
    84721 tagcagcaat caaatcacaa aatggtgctg cgatgtcaat cggacgtatc tcagcattcc
    84781 ttgatatcta tatccaacgt gatttggata atggagtaat cacagaaaaa gaagcacaag
    84841 aattgatcga ccacttagta atgaaattac gtatggtcaa attcgcgcgt acacctgaat
    84901 ataaccaatt attctcagga ttccctatct gggctacttt atccattgca ggtatgggat
    84961 tagatggtcg ttcattagtt acaaagaatg atttccgtct gcttcataca ttaacaaata
    85021 tgggaccttc accagaacca aacttgactg ttttgtattc tgaacacctt ccagaaggat
    85081 tcagaacata tgctagcaga atcgctatcg aaagttcttc gattcaattc gaaaatgata
    85141 atcagcttcg tgaacaatgg ggttctgatg attgtgcgat tgcttgctgt gtatcaggaa
    85201 cagttgtcgg aaaagacatg caattctttg gcgctcgtgc taacttggct aaaacactat
    85261 tatatgccat caatggcgga gtcgatgaag tgactggcgc ccaagttgga ccagaatatc
    85321 gtccaatcac atcagaaata ctagactttg aagaagtgaa acataacttc atgaatatga
    85381 tggattggtt agcagaacta tatgtcaata cgttgaacat cattcattat atgcatgata
    85441 aatattctta tgaagcagct cagctggctt tgatggattc tgacttgcaa cgcacatttg
    85501 ctacaggtat tgctgggatc tctcatgcgg cagacagctt gtcagcgatc aaatatgcaa
    85561 aagtaaaagc aatccgtaat gaaaaaggaa tagcagttga ttttgaagtg gatggcgact
    85621 tccctaaata cggaaatgat gatgaccgtg cagatgaatt agtttcatgg atcttggaat
    85681 acttcatggg acaaatcaaa cgtcataaaa cttaccgcaa ctcaaaacca acaacttcat
    85741 tattgacgat tacttcaaat gttgtttacg gtaaaaatac aggaaatact cctgatggcc
    85801 gtgaagctgg aaaaccactt gcgccaggag caaatccaag ttacaatgcg gaacaaagtg
    85861 ggttattagc tagcctgaac tcaacagcta aaatgaatta cggctgtgca ttggatggaa
    85921 tttcaaatac ccaaacaatc aatccttcag gtcttggaaa agaacaagat acaagaatcg
    85981 aaaacttgcg taatgtctta gatggatact tctcaaaagg agcttatcat ttgaatgtca
    86041 atgtattcag taatgattta ttgcgtgatg caatggaaaa tccaatgaaa tatccgaact
    86101 tgacgatccg ggtatctggt tatgcagtta aattccgtga cttgacaaga gaacaacaat
    86161 tagatgtctt gatgagaact tcacacgaca gaatgtaaaa agttcgtgaa aaaagttttt
    86221 cgacttagcg tcgaaaggac gttgaatagc catcgcatca aaatcgaata atcagtatgc
    86281 ttatttgaaa gaaacgattt acaggggcag gacttgtatg ttccgtccct gtaaatttta
    86341 cacataacga agcggcaatt gcgaaaaatt ttgttcagaa agcttcgctt cgacagctaa
    86401 cttgtactta aaatgaaatc aaagaaaaga tgtgaactta aatggaagaa aaaacaatcg
    86461 gctatgttca ttctatcgaa actttcggtt cagtagacgg acctggactg cgctttgtcg
    86521 tgtttatgca aggatgccgc atgcgttgcc aattttgtca caatccagat acttggaata
    86581 ttggcggagg gaaagaatac acagcagatg aacttttaga taaagcagaa cgcttcagac
    86641 cttactgggg agataaaggt ggtattactg ttagtggtgg agaacctcta ttgcagatcg
    86701 attttttgat cgaactattt aaaaaagcaa aagagcggaa gatgcatact acattggata
    86761 catgcggaaa accttttacg tatgaagaac ctttcttttc acgttttcaa gaattgatga
    86821 agtatacaga tttactgtta tttgacatca aacacatcga taatgaagag cataaaaaac
    86881 taacgcattg ggacaatgaa aatattttag aaatggctca atatttgtca aaaatcaaca
    86941 aaccggtttg gattcgccat gtactagttc ctgagcgaag tgattatgat gaatatttga
    87001 tccgactaga caactttatt caaaccttgt caaatgtaga cagagtagag attcttcctt
    87061 atcatacgat gggaaaatac aagtgggaaa cacttggttt gaaatatcca ttagaaggga
    87121 tcgaaccacc tacaaaagaa cgtgtcgaaa atgctaaacg attgcttcat acagaagagt
    87181 atacaaaata tttaacgcga taggtcgcat cggaaagaag ataagtattg cttctttccg
    87241 tttttttgct attattaaat aggagaaatc acaaaggagc gaatgacatg tcaaaaattt
    87301 tagtttttgg tcaccaaaat ccagatacag atgcaatcgg ggcagccatt gcgttttcac
    87361 acttgcaaaa tgaattaggt aaagaaacag aagcagttgc tctaggtaca cctaatgaag
    87421 aaacacaata cgcattagac cactttcagc tatctgcacc acgagtagta gagtcagcta
    87481 aagcagaaaa tgcagatgtc atgcttgtgg atcataatga attccaacaa agtatttcag
    87541 atatcagcga agtaaatatt ttagctgtag tagaccacca tcgtattgca aactttgaaa
    87601 cagctaatcc attgtactat cgtgcagaac cagttggatg tacaagtacg attattttaa
    87661 aactatataa agaaaaccaa gtaacaattc ctaaagaaat cgcaggaatc atgctctcag
    87721 ctatcatttc agatacattg ttgttcaaat caccaacatg tacgcctgaa gatgaagcag
    87781 ctgcaaaaga acttgcagca atcgctgaag tcgatctaaa cacttatgga cttgaaatgt
    87841 tgaaagcagg aacaaatcta agtgataaat cagctgcggt tcttcttgat ttggatgcaa
    87901 aaagtttccc aatgggcagt tccaacgttc gtatcgctca agtcaataca gtggacctta
    87961 atgaagtgat ggatcgacaa gcagagctag aagcagcaat ggaagatgaa atgaaagcaa
    88021 atggctacga tctgttcgta ttagttgtca caaacatctt agacagtgat tcagaattac
    88081 ttgttgctgg taaaggaaaa gaaaaagtag aagaagcttt ccaaacaact ttgaccaaca
    88141 accgtgcttt gcttaaaggt gtcgtttcac gtaaaaaaca agtcgtacct caattgacgg
    88201 ctgtatttag ctaatcaaat ggtagtatga agcattcaaa atgaatggat aagcgattga
    88261 tataaaaaga aacatagaac atactaaagg ccgaagaaat ggaggagaat aacagtcaat
    88321 tatgactctt gttcttcctc ctttttacgt aaaagccttt taagtaaaat aaaacggata
    88381 gaaaagagaa catatatgaa ctattattca aaaaataagg aaaactttta tcaaaaactg
    88441 accgatgatc cgcttttttc ttcattgacc gattatctat atgaacatcg agaacaagaa
    88501 acgattctaa gagaattgaa aaaagaattt tcgcaaaata aattttccca ttttcttgat
    88561 ttattgatcg atgcaggatt aatcaagagg gaagaacgaa gatatcattt gaactttcca
    88621 atatttgatc ctaaagatta cttgcaacaa gccacttcgg ctgctgaaac catagctgaa
    88681 caattgaaga gactctctgt tgatgaacaa aaattagcga tgggagaagt tatttgggcg
    88741 tattgtttcg aagatgaacg gaaagaagcg tatttttatg gagtaagaaa cagccgagag
    88801 acagaattgc tgaggacaac tgcaggaaat gagaagtacc gttttatcac actttcctct
    88861 atagaacact tcccgcttac tttggctaat tacttttttg tacagaagaa tcagcttcct
    88921 gtaacgaagg cattcaaaga attagccgaa cttattggag acgtaaatga atcgtacttt
    88981 tttgatcaaa tagaagttat cgttgacagg atacgtaaga ataaatataa aaatcgccgg
    89041 cctagtattt tccatcagtc tctacttgtg acgaatacta taaaggaaga agaatcattc
    89101 acattagaat tacctattgt cgaaaaaaac aattttgaga ttgaattacc aacattggat
    89161 ccttcattga caatggagga aatggccttt cttaaacgac aaatcttttc tgagctgagc
    89221 aagaaattta taccgcatgc attttcttat atcaaagaat atggaacagt tttagtgagt
    89281 aaaacctaag agagcagtaa gcaaaaatta tactgactct tgcaggagga gcctttctct
    89341 tcctttatgg ttaaaagaat tatttgagta ttttgcctat ctaccaccta ttagattcac
    89401 tacatggtct ggaaacaaag gaatgcaaaa aaatggtgag aaatgtggaa tgacaaagga
    89461 agtagtgata agaaaagtta gatttttaaa taatcaatat tatgattcag tcaagtatgg
    89521 cattttatgg gaagaactag ctgattagat taggaagtcc atttgataat ccagaatcac
    89581 taagaaacga atggcgagtc attaataatt tatccaatct tgggttattc ttttagattg
    89641 aagtgtttaa aactaaaaaa gcatttatga agtcgtaata gtcaggcttc aaaatgcttt
    89701 ttattttgtt tgttttttct ttgccacata aatacaccta gactgacgat gaagagcata
    89761 tccaacagat ttcctgcgac ttggatcgtc gaagggttgg tcagtggcat taaagcaagg
    89821 acaaaaaagg aaaacaagct gtaaataaaa caggtgacag gaactaatcg aaagaagagc
    89881 ggacatttca attggctaaa aatgagtgaa aaaataaaat aagtaaaaat ggataaaatc
    89941 acgactaaac cattcatgat aaagaagaaa agcgtattgt gattaaacga ataaaaaaga
    90001 attgctaaaa aagaaaacgt tttaaatgca atcaatacgc ttgaagcttc gtttaacgta
    90061 ccaggatgtc gatgaaaaaa ataggcaccg aaataaacag aaaacagtaa gccgcaaaga
    90121 gaagacaaaa tcaaaaaaaa cggattttct tcggctactg tgatatcaga atgatccaaa
    90181 agcaaccagc ctaatgcact agaaggcgca tgtgaggtct taaggtatga ataacataga
    90241 aaaaataaga tcgtcaaagt tgcaaaaaaa gagcctaaat gtaaaaaatt agtggttcta
    90301 cgttgaattt ccataatatc tccaaattaa attgataagt atataaagta taataacaaa
    90361 ttgatgagta tatgtcgatg ttttttaatc aaaataataa ataaaaactg tctaacattt
    90421 aaaatttaat ttagatatta gacagttttt aagtttgtga gttattttcc ttgtcgtttt
    90481 ctcacttttt tagtccagaa accacctgaa atatattttg gctcataaga aatgataaaa
    90541 gcacgctctt cgatttcttt gatcaggcga tacagttcac gttcgctttt tctaggagaa
    90601 agtatttcga gaactagccg ctcaccttcc agccccattg cagaagtctg tgtcacacca
    90661 taaccgtgtt ctctcagtat acccggcaaa cttttatctt ctgcgctatt tgctggcaaa
    90721 atcgttgtga ccatgatgta tcctaatgcc aatttgtctt caatcaaaat tccgacactg
    90781 atacctactg cgtaacctaa cgcatagaca aataaattca gtggattatc taaacgatct
    90841 aaaacaaggg ataagccgac gatataaatc gtgatctcga ccatactgac aagtggagca
    90901 atcagtcgat agcctttcat tgtcaacatg aaacgtaacg tgttcagagt gatataagca
    90961 aaattaatga ggaagatcat ccccaacatt tttggatcaa tcatttgtaa aactcctttc
    91021 atttatataa caacaatatc aaaaaaaatc gtaagtgaag aaaaattgaa actttataca
    91081 tacaaaaaaa tgataaaatg attataatag aattataaag ataggttagg tgattaaaat
    91141 gaaaacggtc aatcgtgtgt tttgtgccag ccacgtgcta agtctccttc tcagtatata
    91201 cttaggtgtc tattcgattc aacagccaat tgaggtagag aacattgttt ttcagatgtc
    91261 gctgacagat ggtttaattt taagcgtttt tttctttttg atactgttta ttggtaatat
    91321 tttcggtagc gttgccagtt ttttgaattt ttctatttat ccactccttt cgctagcatt
    91381 aggagtggtg ggactttgtt ctctgtgctt atttcccgag ccattcagtc ctgcatttat
    91441 attatttggt acactgaacc tgttccagac aactgttgga gcatggttgc tatggcgatc
    91501 aggaaattta atgaaaatag gtgagtaaca attgaatcca attatattga aacgttctgt
    91561 ccatcatatt ccagtgttag aagttgttct gaaagaatta agagaggaac gtattcccgt
    91621 tgtcatctat tatcacggat ggcagacaag taaggagtta gttttgacgc aaggaagaaa
    91681 aattgcgcag cagggcattc gtgtgatcct gccagatgcg atgaatcatg gggagcgcaa
    91741 acagccggtt tcttctattc catcctatac attttgggat agtatctacg gaaatctgtt
    91801 tgaatttgac acacttatca agcatttaga aaaaagaggt cttctacatg atcagcttgc
    91861 agttggcggg gtttcgatgg ggggaatgac aacatgcgcc ttgttggcta aacatcctca
    91921 tatagtagcg ggcgtgtgtt tgatgggttc ccctgcacct ttggaatatg gaaaagaaat
    91981 cgtaaggcgc gcatcggaat ataattatgt cgtaccaaaa gactattttg atttgatttc
    92041 atgggttaag agctatgatt tgtcattgca gccggaaaag ttagctggac gtcctctgtt
    92101 cttttggcat ggacaagctg acgaaaaaat cccttatata caaacggaac gatttgtaga
    92161 aaaaaatcgg cataagtctt acggaaaaga aattgttttt cgttcctcaa aaacacagcg
    92221 acatatggta caaataccac taatggaaga agcttccact tttttagcaa aaaatttgat
    92281 aaaaaagtat aaataattga aacggaaaat cactcatgac gatagaggat tttccgtttt
    92341 ttattttggg ctataataaa ctctgttagg aaaatttggt ataattgata gtaagaatga
    92401 caacatgtta gaaaggaaga gagcatgccc actttagcag atgttgcaaa acgtgccaat
    92461 gtttcaaaaa tgacggtctc tcgagtcatc aatcatccgg aacaggtgac tgacgaattg
    92521 aaagagttag ttttctcagc aatggctgaa ctggattacc gtccaaatat tgctgcaaaa
    92581 gcacttgtca cgaatcggtc gcagatcatc aaattattta tactggaaga aatcgacaca
    92641 actgagccct attacatgaa tttgctgatg ggaatcgcta aacggatcgg taaagcgcat
    92701 tattctctcc aattagttac aaatgatgcc ttcgacgtcg gttcttgtga tggatacatc
    92761 atcacaggtg tcagaaaaaa agacttcgat tggatcgacc gtttggaaaa accagttgtc
    92821 ttgtttgggg aaaattctga aggatatgat tatgtagaca gcgataatga atatggtaca
    92881 gcaaaagcaa cgcaatatgc cttagaaaga gattatcaaa cgattattta tatcggtatc
    92941 gaagtggacg agccttttga aatttcaagg gaaactggtt atttatctgt gatgaaggaa
    93001 gttgatcttc ctagtaaaat cttgcggttt ccaaatcatt cgacagaagt agaaagatat
    93061 atgacagaaa actgggcaga ttttacagat aaaacttgtt ttgtatgtag ttcagatcgg
    93121 ctagcactag gagcagtaag agggattata aatgctggag gacacttgcc cgaagaattt
    93181 ggtgtgattg gatttgatgg ggtattttta gaccaaatca gttcacctaa attgacaacg
    93241 atcaagcaag atattatacg tatgggtgaa gtatgtggag aaatgttgtt aaaaaaaata
    93301 gaagaaaaag gggcgagtca aggttatcgt cgtttttttc ctgaactagt tatcagagag
    93361 acaacgaatt aagtcttatt actatatata tatttatgaa attcatcgct attttcttaa
    93421 aataatcagc gcattgctac tgaaaacaat gaatctgtgc tattattgag aaaagttcca
    93481 tttttgagaa ggatggtttg aatgaaagaa atcagacgaa aacatttccg ttttcctgcg
    93541 tacgatgatg agttaggcgt aaaattaacc aacgacaaga agcgagtatt atttgacgga
    93601 caagaagatc ttttgactga acagaatcag tccccgtttg aacagatgaa agaatttcat
    93661 ttcacgaaca cgaacaccga gaaaatccgt cgcaagcgtc gtgcaacaaa tggattgaag
    93721 tcagctccgc gtaaggaaaa tttggaaaag cataaaggaa aattaccgga ttataccggc
    93781 cattaccaat cagaaatcac atcgacagga cgaaaaaaac tttttggtga ttcctctcgt
    93841 tctgtcagac aaagtgaaac aaggacagag tccaagcata ctacacgaaa cgcatctgtt
    93901 gacacgaagg tgcgggagcg ttcttatttt gttcctaaat atgtacccgc atcgattatc
    93961 ccagacccta gagaaagcaa aatttctgag gatcatttaa tcgaatcgat gaaaaaaacg
    94021 gatgactctt atctgttgtt cgatacagaa ccgacgccgt atcaagaaaa aagaaatggt
    94081 gagccgtctg tacgaacatt caatcgaaca aaaacgttag aggaaacaaa gcagtcagaa
    94141 gaaaaaaaat cgaaaaaaag ccatggtatc ttagaacgct cattacaagg attgatcgat
    94201 gatcaaggaa actctttggg agaaaatagc tattttaaat aagtgatata caaatttata
    94261 ttcggctaca gttggaaagg aaacgctgcg gcgtttcctt attttatact ctatccgaaa
    94321 gtttatatcg tatcctcaaa tttttttgag tttaagcgaa ttttttctcc caataagtaa
    94381 gaaaataatg gcaaaataaa aaaacaaact attttcgcag atcgtttgca aaaata
//
LOCUS       DAZKNV010000003        91747 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000003 DAZKNV010000000
VERSION     DAZKNV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 91747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.003"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            14..1651
                     /locus_tag="ACG8M1_000188"
     CDS             14..1651
                     /locus_tag="ACG8M1_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420942.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1796..2536)
                     /gene="truA"
                     /locus_tag="ACG8M1_000189"
     CDS             complement(1796..2536)
                     /gene="truA"
                     /locus_tag="ACG8M1_000189"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFQ0420943.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2727..3362)
                     /locus_tag="ACG8M1_000190"
     CDS             complement(2727..3362)
                     /locus_tag="ACG8M1_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFQ0420944.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3509..4729)
                     /gene="sstT"
                     /locus_tag="ACG8M1_000191"
     CDS             complement(3509..4729)
                     /gene="sstT"
                     /locus_tag="ACG8M1_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFQ0420945.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            4948..5946
                     /locus_tag="ACG8M1_000192"
     CDS             4948..5946
                     /locus_tag="ACG8M1_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420946.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            6142..7977
                     /locus_tag="ACG8M1_000193"
     CDS             6142..7977
                     /locus_tag="ACG8M1_000193"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0420947.1"
                     /translation="MQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLL
                     LLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVL
                     LIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSP
                     SFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYN
                     TKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLM
                     LSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHP
                     FTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNT
                     ETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKF
                     IQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNK
                     EVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTE
                     DSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8037..8753)
                     /locus_tag="ACG8M1_000194"
     CDS             complement(8037..8753)
                     /locus_tag="ACG8M1_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFQ0420948.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(8980..9522)
                     /locus_tag="ACG8M1_000195"
     CDS             complement(8980..9522)
                     /locus_tag="ACG8M1_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFQ0420949.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(9527..9754)
                     /locus_tag="ACG8M1_000196"
     CDS             complement(9527..9754)
                     /locus_tag="ACG8M1_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFQ0420950.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(9833..11713)
                     /locus_tag="ACG8M1_000197"
     CDS             complement(9833..11713)
                     /locus_tag="ACG8M1_000197"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0420951.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(11902..12516)
                     /locus_tag="ACG8M1_000198"
     CDS             complement(11902..12516)
                     /locus_tag="ACG8M1_000198"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0420952.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            12658..13218
                     /locus_tag="ACG8M1_000199"
     CDS             12658..13218
                     /locus_tag="ACG8M1_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0420953.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(13523..13837)
                     /locus_tag="ACG8M1_000200"
                     /pseudo
     CDS             complement(13523..13837)
                     /locus_tag="ACG8M1_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(14091..15726)
                     /locus_tag="ACG8M1_000201"
                     /pseudo
     CDS             complement(14091..15726)
                     /locus_tag="ACG8M1_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16049..16528)
                     /gene="rlmH"
                     /locus_tag="ACG8M1_000202"
     CDS             complement(16049..16528)
                     /gene="rlmH"
                     /locus_tag="ACG8M1_000202"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFQ0420954.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            16956..18245
                     /locus_tag="ACG8M1_000203"
     CDS             16956..18245
                     /locus_tag="ACG8M1_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFQ0420955.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(18284..18889)
                     /gene="ytpR"
                     /locus_tag="ACG8M1_000204"
     CDS             complement(18284..18889)
                     /gene="ytpR"
                     /locus_tag="ACG8M1_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFQ0420956.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(19094..19558)
                     /locus_tag="ACG8M1_000205"
     CDS             complement(19094..19558)
                     /locus_tag="ACG8M1_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0420957.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(19580..19900)
                     /locus_tag="ACG8M1_000206"
     CDS             complement(19580..19900)
                     /locus_tag="ACG8M1_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFQ0420958.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(20044..21123)
                     /gene="pepA"
                     /locus_tag="ACG8M1_000207"
     CDS             complement(20044..21123)
                     /gene="pepA"
                     /locus_tag="ACG8M1_000207"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFQ0420959.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            21323..21673
                     /locus_tag="ACG8M1_000208"
     CDS             21323..21673
                     /locus_tag="ACG8M1_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFQ0420960.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            21896..22843
                     /locus_tag="ACG8M1_000209"
     CDS             21896..22843
                     /locus_tag="ACG8M1_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0420961.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(22900..24318)
                     /gene="pepV"
                     /locus_tag="ACG8M1_000210"
     CDS             complement(22900..24318)
                     /gene="pepV"
                     /locus_tag="ACG8M1_000210"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFQ0420962.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            24467..25312
                     /locus_tag="ACG8M1_000211"
     CDS             24467..25312
                     /locus_tag="ACG8M1_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFQ0420963.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            25316..25756
                     /locus_tag="ACG8M1_000212"
     CDS             25316..25756
                     /locus_tag="ACG8M1_000212"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFQ0420964.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            25806..26000
                     /locus_tag="ACG8M1_000213"
     CDS             25806..26000
                     /locus_tag="ACG8M1_000213"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420965.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            26136..26821
                     /locus_tag="ACG8M1_000214"
                     /pseudo
     CDS             26136..26821
                     /locus_tag="ACG8M1_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(27229..27918)
                     /locus_tag="ACG8M1_000215"
     CDS             complement(27229..27918)
                     /locus_tag="ACG8M1_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0420966.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(27893..30029)
                     /locus_tag="ACG8M1_000216"
                     /pseudo
     CDS             complement(27893..30029)
                     /locus_tag="ACG8M1_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
     gene            complement(30077..31414)
                     /locus_tag="ACG8M1_000217"
     CDS             complement(30077..31414)
                     /locus_tag="ACG8M1_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFQ0420967.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(31666..32025)
                     /gene="rplT"
                     /locus_tag="ACG8M1_000218"
     CDS             complement(31666..32025)
                     /gene="rplT"
                     /locus_tag="ACG8M1_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFQ0420968.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(32078..32278)
                     /gene="rpmI"
                     /locus_tag="ACG8M1_000219"
     CDS             complement(32078..32278)
                     /gene="rpmI"
                     /locus_tag="ACG8M1_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFQ0420969.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(32350..32874)
                     /gene="infC"
                     /locus_tag="ACG8M1_000220"
     CDS             complement(32350..32874)
                     /gene="infC"
                     /locus_tag="ACG8M1_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFQ0420970.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(32918..33043)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            33196..33828
                     /locus_tag="ACG8M1_000221"
     CDS             33196..33828
                     /locus_tag="ACG8M1_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFQ0420971.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(33830..34735)
                     /locus_tag="ACG8M1_000222"
     CDS             complement(33830..34735)
                     /locus_tag="ACG8M1_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0420972.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(34820..35479)
                     /locus_tag="ACG8M1_000223"
     CDS             complement(34820..35479)
                     /locus_tag="ACG8M1_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0420973.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            35795..36739
                     /gene="mvk"
                     /locus_tag="ACG8M1_000224"
     CDS             35795..36739
                     /gene="mvk"
                     /locus_tag="ACG8M1_000224"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFQ0420974.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            36732..37709
                     /gene="mvaD"
                     /locus_tag="ACG8M1_000225"
     CDS             36732..37709
                     /gene="mvaD"
                     /locus_tag="ACG8M1_000225"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFQ0420975.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            37722..38807
                     /locus_tag="ACG8M1_000226"
     CDS             37722..38807
                     /locus_tag="ACG8M1_000226"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFQ0420976.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            38804..39868
                     /gene="fni"
                     /locus_tag="ACG8M1_000227"
     CDS             38804..39868
                     /gene="fni"
                     /locus_tag="ACG8M1_000227"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFQ0420977.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(40117..40920)
                     /locus_tag="ACG8M1_000228"
     CDS             complement(40117..40920)
                     /locus_tag="ACG8M1_000228"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFQ0420978.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(40940..41782)
                     /gene="kduI"
                     /locus_tag="ACG8M1_000229"
     CDS             complement(40940..41782)
                     /gene="kduI"
                     /locus_tag="ACG8M1_000229"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFQ0420979.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(41798..42805)
                     /locus_tag="ACG8M1_000230"
     CDS             complement(41798..42805)
                     /locus_tag="ACG8M1_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFQ0420980.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(42812..43456)
                     /locus_tag="ACG8M1_000231"
     CDS             complement(42812..43456)
                     /locus_tag="ACG8M1_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFQ0420981.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(43556..44314)
                     /locus_tag="ACG8M1_000232"
     CDS             complement(43556..44314)
                     /locus_tag="ACG8M1_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFQ0420982.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(44441..45592)
                     /gene="fucO"
                     /locus_tag="ACG8M1_000233"
     CDS             complement(44441..45592)
                     /gene="fucO"
                     /locus_tag="ACG8M1_000233"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFQ0420983.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(45674..45985)
                     /gene="rhaM"
                     /locus_tag="ACG8M1_000234"
     CDS             complement(45674..45985)
                     /gene="rhaM"
                     /locus_tag="ACG8M1_000234"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFQ0420984.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(45987..46832)
                     /gene="rhaD"
                     /locus_tag="ACG8M1_000235"
     CDS             complement(45987..46832)
                     /gene="rhaD"
                     /locus_tag="ACG8M1_000235"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFQ0420985.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(46846..48102)
                     /gene="rhaA"
                     /locus_tag="ACG8M1_000236"
     CDS             complement(46846..48102)
                     /gene="rhaA"
                     /locus_tag="ACG8M1_000236"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFQ0420986.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(48099..49559)
                     /gene="rhaB"
                     /locus_tag="ACG8M1_000237"
     CDS             complement(48099..49559)
                     /gene="rhaB"
                     /locus_tag="ACG8M1_000237"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFQ0420987.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            49712..50581
                     /locus_tag="ACG8M1_000238"
     CDS             49712..50581
                     /locus_tag="ACG8M1_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFQ0420988.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(50707..51606)
                     /locus_tag="ACG8M1_000239"
     CDS             complement(50707..51606)
                     /locus_tag="ACG8M1_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0420989.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(51771..52595)
                     /locus_tag="ACG8M1_000240"
     CDS             complement(51771..52595)
                     /locus_tag="ACG8M1_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0420990.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(52606..53901)
                     /locus_tag="ACG8M1_000241"
     CDS             complement(52606..53901)
                     /locus_tag="ACG8M1_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFQ0420991.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(53917..54396)
                     /locus_tag="ACG8M1_000242"
     CDS             complement(53917..54396)
                     /locus_tag="ACG8M1_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFQ0420992.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(54402..55430)
                     /locus_tag="ACG8M1_000243"
     CDS             complement(54402..55430)
                     /locus_tag="ACG8M1_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFQ0420993.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(55447..56553)
                     /locus_tag="ACG8M1_000244"
     CDS             complement(55447..56553)
                     /locus_tag="ACG8M1_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0420994.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(56782..59379)
                     /gene="adhE"
                     /locus_tag="ACG8M1_000245"
                     /gene_synonym="adhC"
     CDS             complement(56782..59379)
                     /gene="adhE"
                     /locus_tag="ACG8M1_000245"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFQ0420995.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(59684..60064)
                     /gene="yajC"
                     /locus_tag="ACG8M1_000246"
     CDS             complement(59684..60064)
                     /gene="yajC"
                     /locus_tag="ACG8M1_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFQ0420996.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(60161..61306)
                     /gene="tgt"
                     /locus_tag="ACG8M1_000247"
     CDS             complement(60161..61306)
                     /gene="tgt"
                     /locus_tag="ACG8M1_000247"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFQ0420997.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            61524..62222
                     /locus_tag="ACG8M1_000248"
     CDS             61524..62222
                     /locus_tag="ACG8M1_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFQ0420998.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(62390..65029)
                     /locus_tag="ACG8M1_000249"
     CDS             complement(62390..65029)
                     /locus_tag="ACG8M1_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0420999.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(65648..66679)
                     /gene="queA"
                     /locus_tag="ACG8M1_000250"
     CDS             complement(65648..66679)
                     /gene="queA"
                     /locus_tag="ACG8M1_000250"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFQ0421000.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            66872..68047
                     /locus_tag="ACG8M1_000251"
     CDS             66872..68047
                     /locus_tag="ACG8M1_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0421001.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            68051..68692
                     /locus_tag="ACG8M1_000252"
     CDS             68051..68692
                     /locus_tag="ACG8M1_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421002.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            68689..69606
                     /locus_tag="ACG8M1_000253"
     CDS             68689..69606
                     /locus_tag="ACG8M1_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0421003.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            69603..70274
                     /locus_tag="ACG8M1_000254"
     CDS             69603..70274
                     /locus_tag="ACG8M1_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421004.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(70815..71303)
                     /locus_tag="ACG8M1_000255"
     CDS             complement(70815..71303)
                     /locus_tag="ACG8M1_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFQ0421005.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(71504..71770)
                     /locus_tag="ACG8M1_000256"
     CDS             complement(71504..71770)
                     /locus_tag="ACG8M1_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFQ0421006.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(71770..72033)
                     /locus_tag="ACG8M1_000257"
     CDS             complement(71770..72033)
                     /locus_tag="ACG8M1_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0421007.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            72554..72694
                     /locus_tag="ACG8M1_000258"
                     /pseudo
     CDS             72554..72694
                     /locus_tag="ACG8M1_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(72836..74659)
                     /locus_tag="ACG8M1_000259"
     CDS             complement(72836..74659)
                     /locus_tag="ACG8M1_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0421008.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(75257..77962)
                     /locus_tag="ACG8M1_000260"
     CDS             complement(75257..77962)
                     /locus_tag="ACG8M1_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFQ0421009.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(78268..79215)
                     /locus_tag="ACG8M1_000261"
     CDS             complement(78268..79215)
                     /locus_tag="ACG8M1_000261"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFQ0421010.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            79405..79674
                     /gene="rpsN"
                     /locus_tag="ACG8M1_000262"
     CDS             79405..79674
                     /gene="rpsN"
                     /locus_tag="ACG8M1_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFQ0421011.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(79850..80212)
                     /locus_tag="ACG8M1_000263"
     CDS             complement(79850..80212)
                     /locus_tag="ACG8M1_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0421012.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(80223..81344)
                     /gene="alr"
                     /locus_tag="ACG8M1_000264"
     CDS             complement(80223..81344)
                     /gene="alr"
                     /locus_tag="ACG8M1_000264"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFQ0421013.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(81360..81710)
                     /gene="acpS"
                     /locus_tag="ACG8M1_000265"
     CDS             complement(81360..81710)
                     /gene="acpS"
                     /locus_tag="ACG8M1_000265"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFQ0421014.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(81840..83351)
                     /locus_tag="ACG8M1_000266"
     CDS             complement(81840..83351)
                     /locus_tag="ACG8M1_000266"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0421015.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(83673..85025)
                     /gene="murF"
                     /locus_tag="ACG8M1_000267"
     CDS             complement(83673..85025)
                     /gene="murF"
                     /locus_tag="ACG8M1_000267"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFQ0421016.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(85178..86254)
                     /locus_tag="ACG8M1_000268"
     CDS             complement(85178..86254)
                     /locus_tag="ACG8M1_000268"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFQ0421017.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            86450..88195
                     /locus_tag="ACG8M1_000269"
     CDS             86450..88195
                     /locus_tag="ACG8M1_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFQ0421018.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(88475..88912)
                     /locus_tag="ACG8M1_000270"
     CDS             complement(88475..88912)
                     /locus_tag="ACG8M1_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFQ0421019.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(88896..90269)
                     /locus_tag="ACG8M1_000271"
     CDS             complement(88896..90269)
                     /locus_tag="ACG8M1_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421020.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(90591..91079)
                     /locus_tag="ACG8M1_000272"
     CDS             complement(90591..91079)
                     /locus_tag="ACG8M1_000272"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0421021.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(91101..91703)
                     /locus_tag="ACG8M1_000273"
     CDS             complement(91101..91703)
                     /locus_tag="ACG8M1_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0421022.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        26763 a        19280 c        16408 g        29296 t
ORIGIN      
        1 ataggagaaa aaaatgaaaa aaaacaaaaa ccaaataata gatatcattt ttatgttatt
       61 tctaagtttt gcttacgtca tccctctatt catgtctaag ggaatctatc atagtgtcaa
      121 tcaggatact tactttcatt tatctcgaat cataggacta gataatgtat ggagttctcc
      181 agtaaacttc aataacttcg atcatcatgg aacaatgatg aatatttttt atccatggct
      241 tactctttat ccagcttttt tattttataa aatgatggga aatcttgttt taagttataa
      301 tatctactat ttttttatca cttttttaac aatggtcgtt tcttattttt ctatgaaaca
      361 aataaaaaac aatcgttata tttcgctgtt attttcgatt atttatacat tttccgccta
      421 tcgtgccatt gacatattcc atcgtgcttc attgggagaa gctgtcgctt taacattttt
      481 gcctttgata ctaatggggt gttacgaaat ttatattaga gattaccaaa aatggtactg
      541 gttgtctatt ggcatgacgc tagtagtgta tactcattta ctttctgtcg ctatggtttc
      601 tgtatttatt ggaggaacgt tgtttctttc tttttatttt tgggaccaaa aaatcgctag
      661 actcttaagt cttttaaaag ctaccgtcct cacctttttt ttaagtgcgg gattcttaat
      721 tccttttatt caacaatcta gagcacaaga attgaaagtc ccactgggaa aagaattaag
      781 tggtatggct cctagtgata tgctgacaca tattttaaat aataactata acaactatac
      841 tattggatta ttcttatttc tcggattgat tggtgctttt atttttataa aaaaattaac
      901 tgctgatgat ttatttattt tctttcttgg tgtatttgtt cttttttgtt caaccaattt
      961 atttccttgg caacttttta accatacacc agttaagagt ctacaatttg tctggcggtt
     1021 aaatggtttt tcttctttat ttatagccta tacgatgagt atagtgatct attatatttt
     1081 ttctactaaa aataattcat ggaaaataat ggtctttacg tttcttgcac taatattgca
     1141 tctctcagga gtaagcaatt ctatccatgc taacaaagat tcattaacac ttatagcacc
     1201 tgaagacgct gttgctatag ctgaaaatta caatcatact gattatgcaa acaaagagtc
     1261 aatctatcat cctgatatga ttaataatga tcaatattta ctaggtaacc aggaaataaa
     1321 tccaacaact cattttatga gtaacaaact tacaattgaa ttagataatt cgaataataa
     1381 aaatactgtc ttgacgacac ctatttatcg ttataaaggg caagtggctt ctattaatgg
     1441 caaactagta caaacaaaat tatctaagtt tggcacaact gaattaacta ttcctccagg
     1501 tataaataaa gtcgttatta cttatcagta cacaaaacta gcaattgctt caagatattt
     1561 atctatcgtt actttgattt tatttttact ttatcgattt actttttcta aacaaaaaca
     1621 accgagaaga gaagtacaac attctcacta gatttttatt taagaaagac tttttagctg
     1681 tacacataaa caggctaaaa agtctttttt tatatttctt taatttgctt catacattat
     1741 ttaacatcga tatttatact gtgaaacatg cgtttcatcc attatcaaag tatttttatc
     1801 gataataaac ttcatccaaa aacagacctt gtgcagggac ggtttctcct gcatgttgcc
     1861 gcactttgct ttcaaatatt tcatcgattg tttctatcgg catggcacct gtgccgattt
     1921 ctagtaatgt ccccatgata atccgcacca ttttatataa gaatccgtct ccgacaaaag
     1981 taaaatgaag catttctccc tttcgttcga tagataattc atcaatcgta cgcactgtgg
     2041 atttttttga ttttttcaat gcagaaaaac caatgaaatc atgtgtaccc actaattttt
     2101 cgcaagctgc attcagcttg tccatatcca actcttgagg gaaataaaag ctgtggtttc
     2161 gctcaaatgc tgaaggaatc acgttgttcc aaacataata gctgtatttt ttgcccaccg
     2221 cattatatct tgaatggaag cgctcaggca tttcttcgat tcttttgatg acaatatccc
     2281 gcggaaggta acgattcata aagtcgatca tttctgccag tccaatttct gtgtttgttt
     2341 taaaatttgc tacttgtcct cgcgcatggg tgccagcatc tgttcttcct gatccaataa
     2401 tttctatctc ttcatttgtc atctgatgca atactttttc gatttttcct tgaatggttt
     2461 tatcgtcatc tccaagtctt tgccatcctg aatatctttt tccgtcatat tcgattgtca
     2521 acttgatgtt tctcatattt tagtggctcc tctgtcttcc atttggtctt ctctctacct
     2581 ttttaagatt gtagcacaaa atatagctcc ttgcttctct aagacagaag ctatacaaga
     2641 aaactgtgga aatatatatt tcagaaaaac aaaaaacagc caccggatga agtatccgct
     2701 gactgttcaa tttgacggct caagttttac tgtttgagat gcaagatact caaccaggca
     2761 atgggcacat aattaaagaa aaaactgatt ctttggcaaa aacctatttt attcagtaat
     2821 ggccaagaat ttatagaagg aattcttgcc agtccataaa tcgccgcaaa aagcaaactg
     2881 atcacagaca gtccaaggta taagtggctt acgtccattt gcccattttt tcgatagatc
     2941 aagaaaagaa gaactggaaa caataaaaaa ccactgtaac ctaaacctga tccgatatta
     3001 tggacccatg tcgagacatt ccacgaagat tcatgggtat tgatactgaa caaacctgta
     3061 aagatacaat cacctatacc atagaacgcg atggctgctg taactagggt agctaacaca
     3121 cgagatgtac taacaaatgc agcatacaat gcaggcaatg acaggatgaa aaagatccct
     3181 gaaaccacag accaaataag aaacgctttt cttacaggac tggaaacctc tccaaataca
     3241 ctgatcacgc tcttcatttg atctaattca ggataataca atcctaatac gtacggagtc
     3301 aaaaaatcac tcagcacgcc taataataaa aagaaaaaac caaatttacg taaaaaatcc
     3361 atgatacgcc tccaataaca attacctatg cttttaattg ttattataaa cgactttatc
     3421 ttgatttaac agaaacctct atttacacga acatctatat aactcattaa aaactcgaat
     3481 cattttaaaa atactaaata tctaacgttc aacgttcact taatccatct aaacaatctt
     3541 tcaatttgat tttttcccca cttcttttac gcgcgcctag ctctcctatt gcagtaaaca
     3601 acagatcact tgacgaattt aaggcagttt ccattgaatc ctggataaca ccgataataa
     3661 atccaatacc gacgatttgc atcgcgacat cattagagat accaaacaaa ctacatgcta
     3721 atggaatcaa taacagtgaa ccgcccgcaa cacctgaagc tccacaagca gctaaagcag
     3781 acaaaataca taaaaggact ttcaaaacaa aaggtgcttc aatccctaaa gaatgtacag
     3841 cagtcaacgt catcaaggaa atggtaatcg cggcaccgcc catattgatc gtagcaccta
     3901 acgggatcga tatggaataa gactcttttg tcaatttcaa tctttcagcc aacatcatgt
     3961 ttatcgggat atttgcggca gaacttcggg taaagaaagc gggaagtgcg ctttctttca
     4021 aacaaaagaa aatcaatgga tagggatttt ctttaataaa caaaaacgtg aggaatgggt
     4081 acacaactaa tgcgacaaac agcatcgtac cgatcaaaac aagtaaaagc tgcagatact
     4141 ctgccaatcc agcgattcca gtcgtagcaa ttgattgata aaccaatcct aaaatcccta
     4201 tcggagcaaa tgcaataatc acttgtacga cttgtgacaa cgctatagat atctgatcca
     4261 ccaactcttt tgtcgattct gaacgtgctc gaaaagctag tcccaacaat acagcccaga
     4321 ataagacgcc aaggtaattc gcatcaataa gagattgaac aggattttgt gtgacattcg
     4381 tcaacatagt agataaaaca ctttccaaac tttgcggtgc tttttcagat actgtttctt
     4441 gtaaagtaat aggaacagta aaaattgaac ttacaataac tgctacaagt gcagaaagca
     4501 atgttcccac taaatataag atcaaaatag gcttcacgaa tgtcttattc ccaattttat
     4561 gcttggcaat tgacgccatc gtcaagaaaa aaaccagaat aggtgcgatt gccttcaagc
     4621 aactgacaaa caacgttccc aatattgaaa taaatgtcca tgtggggaaa aagataccaa
     4681 acaatattcc gactaaaata ccaacaacaa tacgttgaac taacgacata tccaaaaact
     4741 tctctaacaa atgaccaccc tttcacaatt ttaacaatca ttgtatcatt ttatgcaaag
     4801 aaactaaagg tataattttc taaaaattct aacaatacaa acaaccattt cttgctaatt
     4861 ttgtactttt tctgtctaca cgttgttttt tgagatattc taagttagga tgttattaat
     4921 gggcaactta tcaggaaacg ttttcttatg tttttgtcca atttttttgt gaggtgttta
     4981 ttcttgaaaa aaataaagaa ggagagttat ggcttcctga caatctttgt cgcttgtata
     5041 atgatggttt tacagcgtat attgatttca gcagtcacta ttcctacata tgcaacaaac
     5101 cctggtcgat tctacatcta tacattttta caaacttccg ttgttattgg tgcaaatttg
     5161 atcccacttt acatgggtta ccaatatcaa aaaatcgccc gtttaaaagt tttacattat
     5221 ttaagtcgtt ttgcctttat attcctaata gccacactag tttgcaatat ctttttttac
     5281 gtacaagctg gcagcttgaa tattcgtgat tattggctta tcctaacacc tatcagtcag
     5341 aattacttta cttatgctgt ttcttgtact ttgctttttt gtagtattcc ttatacagtt
     5401 ggatttttaa ataaattatc gaaaacaaca attaaatatc tactattatt tttaacaatt
     5461 ggattagttg gctgctctac tctatttaat aaagacccgt ttgcattaca gaatggacag
     5521 agtattttat ggatttttta tttattttta atgggttatg gtttgaaaga atggaactgg
     5581 aaagaaaagg tccgctataa gcttcctcaa gtatttatca gcttgattgt tttattcggt
     5641 ttgattattt tgatgacaca aatttcactc atcatcagag gaaatacaga tacagcgctg
     5701 aggttttcta aaccatattc tctcttcgca atgtattata ctttctcttc gtttttattt
     5761 ttagaaatgc tatctgataa attaggtata aaaggaagag gaaattttct tgctgtattt
     5821 ttgattgtca ctcaagttat atgtaatttc cctttagttt cttatcgcgt atctacattt
     5881 atgaaacgtg aatttccaaa ctcagggaag gcatggctga taaatatcgg gcagtttttt
     5941 atttgatatt tattagcagt gtccctccta gttatctttt tattttatat acaaaaaatc
     6001 cgtttcattc atcgtttcat cgaatacttc gcttttgatt cgattgaaca attaactcag
     6061 cgttggaaaa aaagaattca ttggcttttt gttcataaaa gttatttttt agttgcagca
     6121 tttttttact gctttacctt cgtgcagatt ttcgttttag aaccaaaaga aggttggaaa
     6181 gaaactatcc aggttgcctt aaaaatattt actcagcgac aagcacccat gatcctgaca
     6241 atcatcatta ttatgggatt tttcttctta ctattgttga tttccaatcg tttttggtac
     6301 gccttgactg ctaccttgat cattaactta ctgctcacta tttcgacagt aatcaaaatg
     6361 gaaatgcggg aagagcctgt ctttccttca gatttaaaaa tgctgaccgg attgtcagaa
     6421 ctattatcga tggttagccc agtcttatta atcgtgggcg gattgatcct tctcctatta
     6481 ttgattacta gtattattgt acaacgtaga ctacaaaaac agtattcctt gaagattcat
     6541 tggaaacgtc gatttatcag tatcgctgta ttattaggat gtttttcggg tgtctttttc
     6601 attaatcaca aaaattcgcc ttctttcttg ctgtttaatt tatttaaagt aaacaagact
     6661 ttctttaacc agcaaggcgc cgtaaaagat aacggaccag tcattcaatt cctaaacaat
     6721 atcgacatta aaatcatgga agaacctgct ggctattcga aagaaaaaat taatggaata
     6781 atgaaaaagt acaacacaaa ggcagatgaa atcaaccaaa caagaagtga ctggttaaac
     6841 aatcagacga tcgttctcaa tttaagtgaa agcttcagtg atcctgcacg tgtccctaat
     6901 ctgacagtac ctacagaccc tattccttac atcaaaagca ttataacaga aggaacagga
     6961 ggattgatgt tatccgtcgg ttatggtggc ggaacagcta acatggaatg ggaaggactg
     7021 acaggcttga gtatcagtaa cctgtctgct tcgttagtta caccttatac ccagctagtg
     7081 gagcgtcaga aaataagtcc aaatattacc gatctattcg atgaaaaaat agccatccat
     7141 ccttttacag ctgctcttta tcgcagaaaa caagtgtttg ataaatttgg ttttgacagg
     7201 ttctattatt tagacagtcc ggataaatta acttatacgg ataaaataga acaaagccca
     7261 cgcatatcgg atgattcagc atacaaagaa accttgaaag ctttacaaag caatacggaa
     7321 acgtcacaat tcatccaatt atccactatg caaaaccata tgccttatga tgattactat
     7381 agtgaattga actacactgc tgaaggaact gctgtcattc ctaatagaag aaaagaatta
     7441 caaacttata tgcaaggcct tcactatacc gatacagcag taaaaaaatt catccaagaa
     7501 atcgacaaaa tcgataaacc gattaccttt gttttttatg gtgaccattt acccgcaatc
     7561 tatagtggga atgattcgaa aaaatatgga ttagaacagc accagacaga ttatttcatt
     7621 tataacaaca agtatagtcg tgaacaagca gctacgttaa ataaagaagt tgttgctcct
     7681 aataactttg gtgctatggc tcttgagcat gcgaatatca aagtaactcc ttactatgcg
     7741 ttgttgacag aagtatctaa tcatctacct gcattaacaa ttgatcctac agaaagcttg
     7801 tctaatcgtt ttaatggaaa acaggtcttt gttacagagg atagtcaaat tatccaagaa
     7861 aaaaatttaa ctgagaaaca aaaagaaatt ctagaagatt atcgtctgat acaatatgat
     7921 cttgttgcag gtaaccagta cagtgcaaca tgggcgacac aaaaaataaa agactaacaa
     7981 ataaactgag caaggggttg tgataaaaga catgtcacaa ccccttgttt atctcattaa
     8041 tttgcttgtc cataaacgat ttgattaaag ccatttttca attcattatt cgctgtctcg
     8101 ttgaagtaaa gataattatc gggattcccc tgattttgtt gtgtcaccaa tacttttggc
     8161 tgattttgct gaaacccgaa tagatagacg tgctttttca gatatggttc tgtctctgca
     8221 tcggaataga cggctgtgat ttgatagtct gcttgacctg tcccactttc tgaccattct
     8281 gcagaaacag gcactccacc aatagccatc ttccactccc cgttcaaaat agcttgaggg
     8341 actttaagac catataagtc cacactcatt tgattcgtat aacttttgta ttgttgtccc
     8401 attgtttggc cccatttggt cataaatgcc tctaattgtg cggatttgtc tgcattccac
     8461 agtgtttgtt caacttgttc gctgctttct gaagaggaag atgaagcctc tacagaagaa
     8521 cttgaagtag atgtttgagt tgtttcagtc gttttggaag actctgacga agtagaggta
     8581 tctgctgttt ctgtacttgc tgcagttgac ttgctctctg tgctagttgt tgtagtagtt
     8641 gcaactgttg ctttcgctgt ttcttttgtt gattcttttt tcgattcatt cccgttggta
     8701 caaccagcta acaaaaaagc tagaccaatt gttactaaaa tccttttttt caattaaaaa
     8761 actcctttcg attactccca cttctttatt ctatcaaata agcaatgtga ttttattgat
     8821 ttttcgtatt ttctcatcaa tctttcaaat cttctaaaaa ctgagaagca cccgctgatg
     8881 ttgtctgtaa tacatcagcg ggtgcttctt ttattttaat cttcgtgatt ttccaattta
     8941 cctcacgctt tatatttgta tttgaagaaa catagacttt tagtcatcat cgtcttcctc
     9001 atccaaatct tgtcggacag tttttccttg gagtctttgt acttggtaga tgatttcttt
     9061 attgaaactt aaaagttcaa caagcaattg ttgcaagcca tatttttctt ctttttcagc
     9121 taatttgatt gcccgtgtga taaagacatt ttggaaatca aaatcttttg caaagttttc
     9181 caacattgtt gaggctggta aatatttgtt ttgaccatgt tcgtaaattt ttccataacg
     9241 catgacttct tctaaagtag acggaacgat ttcattttca atcactaact catgagagat
     9301 tttattgaac catctcgctt cttgatcagc atattctgaa aaaagggtac ttaattcttg
     9361 cgaagatgta cccaaaacat acaattgtgc ttggatcaat ttcatttctt ctaatttaaa
     9421 atttgctaat acatgcccca ccatggcgcc agcagttggt ttatgatggt cgatatctgc
     9481 ttgttttgtt tcttgaacaa atttttcttc cactatattc attgatttac gcctctttta
     9541 cttttgctga ttggacttca taacctaatt tttccacaac tgcagctaat tgttcagggt
     9601 ggacttcatc tggatcaaag tttgctttga ttttgctcgc attaaacaaa actttcgtat
     9661 tgcttacccc aggctgttga gaaaccgcat gttcgatttt ttgcatacag cttggacaag
     9721 ctagtgtatc taattgcata ataatttttt tcatcgtagt tcttccttcc tttttcttga
     9781 tagtcttatt ctagattaca gcttccataa aaaaattgat tcttatcaag ttttacgatt
     9841 tttcttcttt gctttcgtgt ccaaaataca ataaacgcat cgcgttaaag ataacgatca
     9901 agatactagc ttcgtgaacg aacatcccac tagccatgta aataaacccg gcaaataagc
     9961 cgttgagtaa aaataagacg acaccaatgg caatcactac attttcacgg gtatttaaaa
    10021 cagttttctt agccaagcgg taggcatgaa ccaacgattc aaaattagat tgcatcaaga
    10081 caacgtcact cgtttcgata gcaacatccg ttcctgatcc catagcaatc ccgatatcag
    10141 ccgcagccaa agagggagaa tcattgattc catctccaat aaaagcaacg cgcaatcctt
    10201 gttcttggta ttttttcaca aattgaacct tttcgtctgg taataattca gcatggactt
    10261 catcaatgcc taacatatca gctacataat cagcagtcat ctgattatca cctgtcagca
    10321 tcactaactg ttttgctcct gcttgtttca acttagctaa ttgttcagcg acttctggtc
    10381 gaatcacatc tgacacacct atgatttgag tgattttttt gtcgattgct acaataatga
    10441 ccgagctgcc tgtttgttgt aattgatgta aatcttgtac ttgctttggt gtgagagaaa
    10501 gtttgtgagc ggcaatcaat ttggtgttgc ccgcacaaac tgtatgacca tcaatctcag
    10561 ctgtgattcc ttgtcccttg attgtctgat tatctttgac tgctaattgt tgaaaatcaa
    10621 tgtctttctc ctgagcataa tggatcacgg cgcgccccag aggatgatcg gataacgttt
    10681 ctaatcgagc cactaaagct aagctgtccc cttcatcctc tgtatagttc ttgatagtgg
    10741 atacagcagt agttcctttg gtcaatgtac cagttttatc aaagacaaaa gtatcgattt
    10801 tggaaaaagt atccattgct tcaccgcctt tgactaagat gccccgtttc gctccattac
    10861 cgattcctgc tacattcgaa acaggcgcac caatgactaa agcgccagga caaccaagaa
    10921 ccaaaacagt gattgctaaa cgaaaatcac gactaatcag accaacaacc aacgcaataa
    10981 gtaaaacggt tggagtataa tactgagaaa atcgatcaat gaatttttcc gcatgggatt
    11041 tggtatcttg tgcttcttct actaattcga taattttggc aaaggtcgta tcatctccga
    11101 ccttagttgc ttcaatcgtc acgtagccat ctgctaaaat cgttccagag aagacttcat
    11161 ctccactgat tttgacgact tgtcgtgatt caccagtcac tgcggcttca tccgcatacc
    11221 ctttcccgtc aatgactcgt ccgtccacag gaatagctcc accagttttt actaagacga
    11281 tatcgccttc ttccacgtca tcgatttcca cttcttcagt cgttccatct tcttggacaa
    11341 cactagcagt agatggggcc atctcggtca aagccttgat tgactcccgc gttttggtca
    11401 atgttttttg ttccagatag ctaccaaaca aaaacaagaa tgtaacgata gctgactcct
    11461 tgtattctcc gatcataaag gcaccaagca cagcaatagt aacgagtaaa tcaattgaga
    11521 taactttgac tttcactgcc tgatacgcat ggatcataat aggtatgacc gcaataatag
    11581 aagctatggc tagagcaatg ttatagaaca agacaaaacc agtaaatttt ccgataaaac
    11641 caaaaataat caacacagct gataaggcgg tgatatgatt tcgatgctct tggatccact
    11701 tttgtaattt catctttctc cctcttttcc tttcattctt acgagactaa gtatagatac
    11761 ttatccatca taaaaaattg accactatca agtttagtca aaaaggcggt tttcttttgg
    11821 tagaatacac tacaaaaaat agttagcaag aagactcact aaaagtgatc ttgccaacta
    11881 ttgtcgtttc tatcgaaatt ttcattgaat gattttcctg tacagcatac atcggagatc
    11941 tatttcttta tctaagattt ttatcttgct aattttttcc tttagtcttt caaatccacg
    12001 tcgttcatag aattgatacg tacagccact atctgtaaaa aggaatattt cttttccttt
    12061 ctctcttttt tcaaattctg ttagcaactt ggtaccgatg ccttttgttt tcaaatcagg
    12121 atttgcagct aaaaaaatga tctctccatc tggcgaatgc ttctttaaat atgctgcaag
    12181 catttgttca tttgctgtct cgtaagctcc tttactttct ttagcaaata tattttgtaa
    12241 aaaatcgaat atcttaacat atatttgctg tccaaaagaa cgatgtttct ttttttctcc
    12301 ttttatctcc gccagcaaaa cacctgccaa ctcgtcctct gcatacaaag caagaatttg
    12361 agttgctcga ttcaactcca tatacaaaaa atatcttccg taaagattca gcagaagttc
    12421 attttccata tatctctcaa agttcattcc ttcaacagca aaatagatag cttttttgta
    12481 atctttcttt tctaagggtt taaaagttag tttcatcatt tcgcctcctc aacttcaatg
    12541 attgtgttat acttacatta taatagacac agtgtctact atctataatc aatcatctat
    12601 aagtttgtcg attaagcgac agctttgctt tgatatgtcg gataaggaga taggtaaatg
    12661 aaaaagacag atagacgcgt caaaaaaaca gaaaaagctt tggctgaaac actatccaca
    12721 ttattagtaa ataaaaagat tcaagcaatc actatacgcg aactaacaga aacggcagat
    12781 gtacatcgtt cgacttttta tacacattat aaggatatct atgatctata tgatcaatta
    12841 gaaagcaact tttttcggga tctaaatgaa attctctctt atgatccagc ccatagctat
    12901 gaggaactat acactcgctt gattgactat gtttacgcaa atactttttt atatcgctta
    12961 tttatcctca accatggtga tatttcgttt cagaagaaag ttaaacaagt tattgaagaa
    13021 aactatctga acatatggct atatgaagac aagaaaacga ttatcacaga agaaatgaga
    13081 ttctttacta cgtaccacgt ccaaggttgt ctatccgttc tcaatcggtg ggtagaaagc
    13141 aattacaagt actccaaaaa agaattatta gaactcttac agaaactgaa tgatcacata
    13201 gagaaaatca tgccttgaat aaaaacatac taagcttagt taagaagaac cgtaaccttc
    13261 tcgtataaca actgaatctt atttagccaa attgtttact gaagattttt tgagtaaaat
    13321 ttctataatt cctacttatt gaaaagtagt ttgtagtgct gcttctccct ctctaagtga
    13381 tatatcttgt tgtaccaatc aaattcacct catcattaat aaattacttt taggctaatt
    13441 tattacaact tataggttga agctgtaacc aatttatagt catattatat ttttatcatc
    13501 cagtttattg aattcttctc gtttacctca attcattttc aaggggaatc agctcatcat
    13561 ctaacatttt acgccatgct cgcttcattt cttgtgggta tttaaatggt ttcgcttctg
    13621 gatgtttggc tttatatcct tcgtaatcct tactgttgat aattgctttc atattaggaa
    13681 ttggatcttc acctggcata tattgcagat tagaagcatg taattttttc tcagaaacaa
    13741 accactcatt ggaaaagaca tgaatcaaat catcacttac ttgtgtaaaa tagcgacgtt
    13801 taatgacaaa gatatcttca ttgctatcta gtgtaccttc atttctttgt gcttaaattc
    13861 aaagataatt ttctcaataa agatttttga ttccagtaag attcctttac tccttttaca
    13921 acatagcgtt gtcctttgtt ttgaaacatc ttcttcccct ctttgccatt aaaaatagcc
    13981 caattctcta taaagaagat taagcttcat tattataata taaagtttaa atttggttta
    14041 ttacttactt tttcttattc tctagtaagc taatattgaa aaaaatgtaa tcagatcatt
    14101 atttttatat gttgtaactt cctgataaga aaactaatta aaagaaagag gtaactacat
    14161 aaactaatta aaaaagctaa cttcatagtt ggaggataaa tggaagaaac ttcaatgatt
    14221 gtttctcctt gtgttccttc aatcgacact agtcctatta tcaatctctc ttttttgtcc
    14281 atttactttt gcgactgttc cccaataatc aaatacagga agcgttattt tttgtccttt
    14341 agattcatgt actgtataga ctattttcga atccatcact tgataaggca tagtatgcca
    14401 ttccttgcca attcttactt catgattctg caaatgttct ttgtattgta atgcttccgt
    14461 gggtgcatag tcataaagtc ctccgggaag gagtgtcgtg taacgaataa gattttcttg
    14521 attcattacc aagtgatctc tctgagtgac aactttatgt tcatagtttg cttttgttgc
    14581 agcagataca gccaacagta ataaaacaat tgccgttata ttaactactt ttctttgctt
    14641 agctgatgtg ctcttcatga aaacgaacga taaaatcaac gagccaaaca gtacttgaaa
    14701 gcctaagatt cgccaaggaa attgaatcat ttgaatgggt gtattttgta ataaagacca
    14761 tggaaaaaat ttggtggata agagccaaga gactaccgca ctaaggtaaa tcactttttc
    14821 tttgcgatta aatcctttaa aaaagaagag tggacagatc aaagaaataa taccaatgat
    14881 tcctaccgta aaggttgtca ggtcattatt catcgcacca atcaaactat ccgagacatt
    14941 taatgcttgg tgttgtaagg tcgttttatc tggctcatta atcgattgaa ccatgatttg
    15001 tcggaacatc ggataccaaa agtatgctgt taaaagaatc gtcattccta ctgcctttga
    15061 caactccaca atcaaccgga tgctttcttt ttttcttgtt tcacttacta caaagccgcc
    15121 taagactagt aagccaacgg ctattacact cataaaagtg gaaagaacat gtgtataaat
    15181 gagtaagctc atactgactg ctaatggaat tgcacatggc tttttctcat aaatcagtgc
    15241 gtaagcataa tacataacta tcggtataac cgtaagtgca atcgcttcag caatagcaga
    15301 acgatgataa atatcaatcg tacggtaccc ataaaatgta tataaacagc taaatataaa
    15361 agccgcatcg attcttttta aaaattttag tccataatga aacatcagca tgatagtaca
    15421 aacattcaat agccaaacat ataagatata actaacgatt aaattattac ttatccaata
    15481 aaaaatgact gccggaaaaa aggtcaagta gggataaaaa taattcactc cgctcccata
    15541 atgattaaac gtcgtaaaat tgattggacc agaaaaaatt gaagataacc ctttgactct
    15601 agcaaaatgg aaggcaatat cccccgatgt agaaatagta tgaacatttc taaaataatt
    15661 gattgaataa agtccagcaa taattgctag gagaatggac aatattattt ttttctttac
    15721 ttgcattact taattatata ctcctttcat ggattgcttt atctagtata acttaaattt
    15781 taaataaatc gttatttatt tttactctca cttaaaaaag cactaaaatt ataagagagg
    15841 gaggtaatgg tctgaacacc aagaattgtt ccaacatcga attgcttaac taatgagttc
    15901 aaagcttaat tatgtggctc ttatatttac cgagcgtgga ttgcgatctc tttagcgaaa
    15961 caaacatctt tcataaaaaa aacagccata tccgctttct tggatatgac tatttactac
    16021 tactttacta tctttcattc ttcttgtctc acttatgata aggcgccccc gcattgatcc
    16081 ggaaggcacg gtagatttgc tcgacaagga tcagacgcat caattgatgt ggatacgtca
    16141 tttttccaaa agagatctga gcattgcttc ttttcatgac ggcttcgctg agtcctaaag
    16201 agccgccgat aacaaaaaca aggtggcttt ttccttggat acctaattgg tcgatttgtt
    16261 tagcaaaaga ttcacttgta ggatttttcc cttcaattgc taaggcatag acgtattctt
    16321 gttctttgat tttcgctaag atccgttccc cttctttttc ttttacttgt ctcatttgcg
    16381 cttcgcttaa attctccggg gctttttcgt caggaacttc gatcaattcg atttttgcat
    16441 aggcattcag ccgtttgaca tactcattga taccttggat caggtatttt tcttttaatt
    16501 ttcctactga gataattttg atattcatgt tttctctcct ttggtcttca tgctcacttt
    16561 gtttattata atcaattttt tcgtctatat gtttattttg gctatttttg ttaaaaagat
    16621 ttccccaaca gttatgcaca acatccacag gtttatccac agaaaacagt gttattttac
    16681 cttatttcat cacattcatt aggcaaacat acgttttata agaatttatc cactttatac
    16741 acaggctgtg gatatgtttt atcccttatt tttccaatcc tatccgcgta gttttacaca
    16801 gtatctgtgg aaaaagaaaa tcaaatattt tcatctgaaa acaatgattt ttcctaaagt
    16861 ttttcataaa aagttcacag tctcaaagta gactaaagtc aacaaataag actatactaa
    16921 cagtagataa atgaatgtaa ttggaggagg aacacatgga tagaaaaaat gtgacaccaa
    16981 agatgaaaaa aagtaaaaat aatagcctct ggcgtaagtt aggtctgggg cttgttggag
    17041 ggatcgttgg aggactactg acagctggca ttttttatgc agcgatgggc actggcaaca
    17101 atagttctac tgctacaagc ggcaatcaga attctgccgg tgaaacagtt gtggaaaatg
    17161 tcaaagtcaa tgtagattct gatatcacca aagcggtaga taaagttcaa gacgctgtcg
    17221 tttctgttat caacttacaa agtcaaaacc aatcaagcgg ttttggcgga ctattcgggc
    17281 agcaagaaga aagtagcagc tcagatgata gtaatttgga agcttatagt gaaggaagcg
    17341 gcgtgatcta caaaaaagac gggaatactg cttatgtagt cacgaataat cacgtagtag
    17401 atggccagca aggtcttgaa gtcttgatga aagacggtac gaaggtaaaa gctgaattag
    17461 ttggaacaga tgcttattca gatttagcgg tgttgaagat caattcagac aaagtcgaaa
    17521 cagttgcctc ttttggtgac tcaagtgctc tgaaggttgg tgagcctgcg attgcgattg
    17581 gttccccact aggatctgaa tatgcaaatt ctgtcacttc aggaatcatt tcttccttga
    17641 accgacaagt gacaagtacg aatgaatcga acgaaacagt caatatcaat gcgatccaaa
    17701 cagatgcagc aatcaaccct ggaaattctg gtggtccttt agttaatatc gaaggacaag
    17761 ttatcggtat caactcaagt aagatcgcaa gtacttctga atctacttct aatgtaagcg
    17821 tagaaggaat gggatttgct attccaagta acgatgtagt gaatatcatc aatcaactgg
    17881 aaaaagacgg aaaagtgaca cgtccagctc taggtatcac aatggtcgac ttatctgccg
    17941 tttctactca gcaacaagaa caaatcttga agattccttc atctgtaact aacggtgtca
    18001 tcgtgacaaa tgtccaaaca gctacaccgg ctgaaaaagc tggattgaaa caatacgacg
    18061 tcattactaa gatcgatgac aaagaagttt cttctggtgt agaacttcaa tctgctttgt
    18121 ataagaaaaa agtgggagat tctgtcaaaa tcacttacta tgaaggctcg aaagaaaaaa
    18181 caactactgt tgaattgacg atcgatcaat cggcattaaa acaaaatcaa aatagtgaaa
    18241 attaataaaa aagaggttgt gacaaagact tgtcacaacc tctttatttt ggaaatgctt
    18301 ctccgactac ggcatcctca ggcaatacta agattccttt ttttgctgga gcatttggca
    18361 aatgcaattc acgagcggaa cagatcattc catagctatc tacccctcgc aaagttcctg
    18421 gccagatcat cattccatct ggcatcatag ctcctggttt tgcaacgaca actttttgtc
    18481 cagcttcgat attgggtgca ccgcaaacga tttgcaatac tgtaccattg tctacttctg
    18541 tctcagtaat cgataaatgg tcagaatcag gatgtgggac gcatgttttt acgtacccga
    18601 caacgatctt cggttcatga tcagcttcaa gctgttcttc gaatcctgct tctttgatca
    18661 atcgattcaa tttcgctaat tcctcatctg ttaagcttac ttggccgttc ccttcgattg
    18721 ttagatgatc ggagatatgg aaaaagttcc aagcaacaac ttgaccttgt tcatctttga
    18781 tccgagcaac attccatttg cgttcaacag tgttttctgt tcctttatcg tcggctataa
    18841 taaccatcaa ggtgtctccg acgtgtgctt tgttataagc aaaaatcatg ttctttcctc
    18901 cattatcctt tgctgagatt tatcttaaca aaaaattgca ttcactgcat gaaatttttt
    18961 tcatgcttta tttccgaaga agcctcttct ggaacaccat ttattcgtaa caagggactg
    19021 tgacaagact tttgtcacag tccctttact gttttagtta attgattaaa aaggtcgtac
    19081 aagttccact tgcttaatta cttggctgtt cttcttcgtc agaaacgatc aagacatcac
    19141 aaggtgaatg acgtatcacg tagctggcta cacttcctgt cataaagcgt tcgactgcat
    19201 ttagacctga ctgcccaacc atgattagat cgatctcata tttttttggc aatttgactg
    19261 ccatggattc acgaacagaa ccatatgcaa taattccttc tatatttgtg taatcaacag
    19321 atttcccata ttctttacat tcttcgatca tttccttggc tgtttcagtt tgctgatcga
    19381 ctagattttg atcaataggt gcatagccca taaagttata aaattgctga tcgattacgt
    19441 ttgctacata tactttccca ttattacggc gagccacttc taccgctttt ttgaaagcag
    19501 caagtgcttg ttcactaccg tcgataccta ctaaaatatt cttatattct tgattcatct
    19561 tgacccctcc taacagatgt cagccttttg ttacactttc taggaacgat tcgatttcct
    19621 gttttgtttt acgatcttta ttcactagac gacctaattc ttttccgtct tggatcacga
    19681 caaaacttgg gataccaaaa atgttccatt cagcggctac atctatgtac ttgtcacggt
    19741 ctacttcaat aaattgccaa tcagaaaagt cattttcaat ttcaggcatt tgcggtttga
    19801 taaaacggca gtctccgcac cagccggcag taaagaaaaa tacactcttt ccagtttcta
    19861 cgtagcctgc taattcttct aaactatttg ggataatcat tctttgtcct ctactttctg
    19921 tttatgtatt tttcaattaa attatacacc tttctttcga actaacaaac attgatcctc
    19981 tttttataaa aaaaatctgg caaaaagcaa tcttttgcca gattttatag tttcactatc
    20041 gcattatttt ccgtatacga tcgtatttac tgttgattta tccaaacctt tcagtgtttg
    20101 aatcaacatt tctcgtgcag cttcaaaatc gcgaatactg aacatcgttt gatgcgtatg
    20161 gatataacgt cccactacgc caatcactgt acttgggatt ccttcgtttt gtgtatgagc
    20221 agcacctgca tctgtaccgc cttttgaaac aaagtattga taagggatat tgtttgtttc
    20281 agcgatatcc agcaagtact cgcgcaaacg aggaagcatg atcaaacctg gatcttggat
    20341 acgcatcaat gtaccttctc ctaaatgtcc gaatgtgcca tttttcgtca ctgtatcatc
    20401 tgctgcagag cagtctactg caaagaacag atctggcttg aatttattga cagaagcttt
    20461 agaaccacgc aagcctactt cttcctggac attcgcgcct gcaatcaatg tatgacctaa
    20521 tgtttcattt tgcaacgctt ctaaagcttc taataccatt gtacagccat agcggttgtc
    20581 ccatgattta ctgataatat tctttccgtt ggctgttttg atcgtttcag cgtaaggaac
    20641 gattgtgtct cctggaagga caccgtaact cattgcctct tctcttgatt caaacccagc
    20701 atcgaacaaa atatcggtta cttctactga tttttgtccg cttgttcctc gcaataaatg
    20761 tgggggaacg gaagaagaaa tacatggata attcttacca gtagaggttt taagtgtaaa
    20821 acgctgagca gaaacaacgt aaggattcca gccgcctaga ggtacgactt taaaaagccc
    20881 gttttcttgg atttgtgtca gcatgaatcc gacttcatcc atatgtgctg cgaccattac
    20941 acggggtgca tccgcttctt catgatggcg cagaccaaaa atgccgccca aaccatctaa
    21001 ctgtaactca tctaccagcg gttccatatg actttccata taagcgcgaa catcttgttc
    21061 aaaaccgctt gttccttgta attctgttaa ctctttgatt cgttgaaatg ttttttcttc
    21121 catatgctat tcgtctaaat ttcagactaa actcctctca gacttatatt gatctgcgga
    21181 taaaatatga ttttttctgc agaccgatcg tatttattat agcttatttt ttctggtagc
    21241 ggttatttat ttcaaagaaa atatgagagt gtggtaaaat aagcacaagg agtaacaagt
    21301 gagaagaagg aggtatgtcc acatgtatga agaaagcgaa ctaagctatt ttaaaggcgg
    21361 gttagcagtt ggaatcggtc taggattatt gagcggggta gcttcaacga tttggtatca
    21421 tcgcaaaaaa gtattgtcag cagaccaagt acttgaaaat atcaagtcat cttttctaaa
    21481 agaaggtgca atcgaaggtt cttggatctc ttttgaaaag gaacctatta ggaaattcgc
    21541 cgttcggtcg agtgcttatc ggggaggtct ttctcgaata gaagatggcg aaactgttta
    21601 ttatgaattt ttagcagatg ctcatacagg aaccgtatta gaaatttcaa gaaaaaaagg
    21661 tgcaacagat taatacgtca aaaaagtgag agaacgaata cgcacccact attcaaaaga
    21721 gaggtatcat gtccttcttt tgtagtgggt ggttttttag atagagcttt ccaaacatat
    21781 attccagtat tttcttttta aataaatgat atttagcggg aaaaactagc atttcctttg
    21841 attatgaggt atttttaatt tagcttttgt tttctatagt taaggagagt gaaaaatgga
    21901 acaacaagaa aaaattgctg ttctgattcc ttgttacaat gaggaagcaa caatttcaac
    21961 agtcattgca gactttaaac gagaattacc agaagcagat atttatgtct atgataataa
    22021 ttcgaccgat cgaacatacg aattggccgt tcaaggtgga gcaatcgtaa aaaaagaacc
    22081 tcgtcaagga aaaggaaatg tgatccgcca aatgttcttt gatatcgatg ccgactatta
    22141 tttaatggta gatggcgatg atacttatcc tgcagaagct gtacatggtt tgctcgagaa
    22201 attacgttct ggtgaagcag atatggtcat tggtgatcgc ctatcaaatg gaacctactt
    22261 tgatgagaat aagagacctt tccacgattt tggaaataac cttgttagaa atacaattac
    22321 tagaatgtat aaaacaaaaa ttcttgatgt catgaccggc tatcgaggat tcaatcgtat
    22381 ctttgtcaaa agttttccta ttatgagttc tggttttcaa atcgaaacgg aattgacgat
    22441 ccatgcttta gataaaaaat tcaagttcgt tgaaatccca atcgattatc gtgatcgtcc
    22501 tgaaggcagc gaatcaaaat tgaatacatt ctctgacgga ttcaaagtga tcatgatgat
    22561 tattaaaatg tttaaagatt ataagccttt gcttttcttt gggatttgga ccattttctt
    22621 ctttttattt ggattggtca cggggattcc tgtgattcgc gaatatatgc tgacaagctt
    22681 tattacacgc atcccttctg cgattttaag tactggattg atgactttag cacttctttc
    22741 attagtaaca gggttgattt tggatacagt cgtcacgaac gctaagaaag aatatgaatt
    22801 gaatctatat catgtttatc atgaatacca cagtagaaag taaaaaaagg atcaagactg
    22861 caaaaataat ttgcaattct tgatcctctt tttaattaat tatttcgcca aacgatagat
    22921 ggcatctgca tagattgctg ttgctctgaa caagtcatca agactcataa attcgtttgc
    22981 ttgatgcatt gtatcagtat atcctgggaa catcgctcca taagcaacgc cacgtttcaa
    23041 caaacgtccg taagttccgc caccgatgat ttgttcgtag cctttttctc cagtgtggtc
    23101 ttcatagact tgcaataatg tagccaccaa tggatcatcc attggtacgt aatgtggttc
    23161 cattacgcga gcacctcgag taactgttgc gccttcttgc cccactgttt gttcgatgtc
    23221 actttgcaat ccgtctactg ttacaccttt tggaaaacgg aaattcatat tgatgaagtt
    23281 cgcttcctct gtaccatttt cttcaaaagc aaatagtcca gcattcattg tcaatttgcc
    23341 cattttttca tcttcataag cgactcctag tttttctcca taaaaatctt catggacata
    23401 agcagctgct acatggataa attgtttagc agatcctagg aattcatagt tatctaagaa
    23461 caatgccaag aaagaacctg cattgatacc agattgtggg cttgcaccat gtgcgccttt
    23521 accaactaat tcgattttta catacgtatt gtccgcttca atcgttccgc ttactggatt
    23581 tgcttcgatg aattggtaaa atgcttcttc catcgcgata gctgcatctg cacttggtac
    23641 ttgaagtgct gcagttgctg ttcctggcac catattttcg cgaagtccgg aaacaaaaga
    23701 tttcaagaca taatctcctg cattgtcgcc tttgaagcgt aaagctaaag aaacatttcc
    23761 tttttcacca ttgatgattg ggaattcagc atctggtgag aaaccaaaat ctggttcttc
    23821 ttcatgttcg aaataataag ccatatcgcc ccagccgctt tcttcatcgc tgccgactac
    23881 gaagcgaact ttttttgata gtttcaagtc aagttcttta atgatcttca tcgcatagta
    23941 agctgccata cttggacctt tgtcatcgct tgatccgcgt gcaaagatct ttccatcctt
    24001 gattactggt tcataaggat ctgtgtccca gccatctcct gcaggaacga catccatgtg
    24061 tccaaatatc cctagcgttt cgtctccttc gccaagatca atatgccctg catagttatc
    24121 gacatttttt actttaaatc catcacgttc gccataagct aacatatgtt tcaatgcgtc
    24181 gcgaggtcca ggtccaaatg gtgcatctgg tgttactttt gagtcatcgc gctcgctgtt
    24241 gacacgtaaa agatttttca agtcttcaag caagtcttct ttacgtgctt ctacttcttt
    24301 ttgccaatca attgtcataa agttaatcct ccacttattt aagtcttcgt gttcatgata
    24361 ccacaaatta cagaaaaaaa tagttcaaaa aatctgacaa ttccttttct tatctgtttt
    24421 tctctaaaaa aaatatacgc tataatgagt aaaaggaggt ttttagatgc tgataaacga
    24481 acaactagtg aaaagagtca tcacacctcg tccaaaaatt tcacataaag gaacatttgg
    24541 acgtatcgtt ttgattggcg gcaatgaaca atatggcgga gcaatcatta tgagtgcttt
    24601 agctgccgta cacagcggag cgggtctcac gactgtagta actgatgaaa aaaatcggag
    24661 tgctcttcac agtcatctgc cagaagcaat gattgtagtt tggacggata ctgaccagtt
    24721 tctttccgta ataaagcaag cagatgtact cttgattggt cccggattgg gtacttcttc
    24781 taagagtttg gaacgtttca aacaagtact agaaaaccaa tcaaaagaac aatggctggt
    24841 gattgatggc tctgctttaa gtttacttgc tgctaatcat cttttgctac cctatcccga
    24901 acaaactgta cttacacctc atcaaatgga gtggcaacgg ttgagttctc taccgataca
    24961 agaacaacgg gataaagaaa acaaaaagaa gcaacaggaa atcggtgctg tgctcgtttt
    25021 gaaaagtcat gagacaaaaa tttatggtca ccagcacttc tacaccaatc ctttaggttc
    25081 tgctgctatg gcaacgggcg gcatgggtga cactttagct gggatgatca caggattttt
    25141 agcccagttt cctcaaaatg accaaacgat tgcagcagct atttatcttc atagtttcat
    25201 tggagaccag ctggcaaaag aacaatatat tgttttgccg acacaaatca gcgaagcact
    25261 tccgaaatgg atgaattatt tttgtaaaaa atcaatggaa aacgaggcat gagtcatgga
    25321 gaaatttaca ggttatgtgc gagaaccttt ttattatgaa acagatcaaa tggggattat
    25381 tcatcacagc aattatatcc gctggtttga agaggctcgg gtagccttat tggtacatct
    25441 agggtttccc tataaaaaaa tcgaagaatc tgggatcatc atccccgttc tggaagtaaa
    25501 ttgcagctat aaagaaatga tccattacgg agaaaaagtg agcatccatc caactatcca
    25561 aaagtatacg gggacacggt tggattttag ctacgaaatt gtgggaactg aagacaaaaa
    25621 attaaaaact actggcagta gtaaacactg ttttttactt tctgattcgc aacgattagt
    25681 gaagctgagc aaagtcaatc cggagttaga tcagttattc caagcgtacg cttctttgga
    25741 tgatgtaaat tcttaataaa gaccgtctaa gcatttttct tgtattgtgt cgagtagttc
    25801 gtataatgaa aagaaaaaag caggtgatcc ccatgtatgt cgttaaagta atgcacggtt
    25861 acatcgataa aactggctgt cgcactcggg aaaaaaactt agacaatctg ctcattttca
    25921 aagacaaaaa agaatccgaa gcttttgcta aaagaatcgg cggtcgtgtc aaaccgatcc
    25981 aagaggtacg accagattga ttcaatattt ttcttttcga ggctctaata ggcatgccta
    26041 tcagggcttt ttttgcagac tgtgttttta tgcccacacg atttgtaagc gatttatgtt
    26101 ataatagatt atatctgcat agaaaggaag gttaaatggt tatcaataat ttgcaacagc
    26161 aagcttatga atctatacgt aaacaaatca tttattccga gttagcacct ggaagtaaaa
    26221 tctccgataa agtgttagaa gaacaactag ctatcgggcg tacaccgatt cgagaagcac
    26281 tgatccaact gcgcaatcaa gagcttgtaa aaaccattcc acagtccggc acttatgttt
    26341 caaaaatcga tatccgatct gcttcattag cccgttatac gcgggaaaag ttggaaaaac
    26401 cgatcctgca agaatgcagt gcgaaaatga ccaagcaaga tcaagctaaa ctagaaaaaa
    26461 tactagaaca aaccgatcag gcagtaatcg ctcaaaataa aaaagctttt ttgatttgga
    26521 tactgatttt caccgaactt gttatgaaat tgctggaaaa cgagaaattt gggattggct
    26581 agaaagttat agtacgcact tgaaccgttt cagatggtta cgtttgacga tttcagaatt
    26641 agactggggt cgagtattag atgaacatca gacaatgctt caatcaatga ttgatcataa
    26701 ctttgatgaa gtcggatttc tttgcacgat gcatttacat atgattatcg aggagcaaga
    26761 atacgtgatt cataattacc ccgattattt tgaagatatt caggacagac ccatcaaata
    26821 agaggttttg gaatcagcgt tttgacctga gtattagaga aagaaacggc aaaatagttc
    26881 ctcatatttt gccgtttttt ttgagctaat accgagggtc agctgattgc acaccgttta
    26941 ttgagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacagccaa gtaaaaatag
    27001 cttcttatgt ttttaacttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt
    27061 tttccaagag gtcgtgagcc tgccgttcat ctccgagtca caaggaacaa tttcaaaaaa
    27121 cagcttctca tgtttgttga atattttgac ttgtgaccga ggagttgaca ggagaacatc
    27181 gtttattcgg aaaaaaagga ctgtgacacg acttttgtca cagtctcttt atttgtaatc
    27241 taaatcatac tccgtacatc ttttttctat tttttttatt tcttctaaga tcccttggct
    27301 acgaatttca ttatatggcc aaagtaagac tgcctctaat acataaggcg aaaaatcgct
    27361 ttgattcatc tcttttgaaa aactcatcgc tgctatctcg ctcaatgcac gaatgtttga
    27421 ttgatgtgta taaaaaggca accgccacag cacaattttt tcgctttgcg tataaattcc
    27481 cttaacagaa gcttcgatgt ggtgaaatag ttcatgtcca ataatcaaag cttgcgctgt
    27541 ttctttagag atcgaagcta gtcctgaaca ttttaatttt tctaacggct ccgtcatcaa
    27601 tcgaatccct tcatcttctg cataagttgc aaaagtgatt cgttcgttta tttgctctga
    27661 ttcacaggaa acgattggaa cagccatttg ttcacaaatt tctcctacat cggcaaaagg
    27721 gtactttttt ttgatgctac atgccgtttc gataccacaa tcgattgatt gttgtataag
    27781 aattttctgc ttggacaaag gaatcttttt ccaaaataaa tctcgccgaa actggtagaa
    27841 tccccaaatt tcttcgggga tctgttgtaa ttcgtttagt aactcttcta acttatgttt
    27901 gtttgatatt tccggcaacg acgatcactt cttcctccgg ttccatagta gatacttcca
    27961 gatccatcaa aagctgtagt tgttccagat ccgtcgctgt aaaatcagag actcttgctc
    28021 ctaagcagag ataaaattct ggtcgggcaa tcaattcagt ttgataaact gccatatctt
    28081 cccaaagttg ttcgacagct gtcatataat tggctgcagt tgttttcata catgaagcat
    28141 gtccacgttg gaccttgata aatccttttt gatcgatgat ccgaagactt ccagcatttt
    28201 ttgaacgatt ctgttcgccg catacataaa agaaaggtgt attttccaat aagcaaactt
    28261 catttttatt taatcgcata tcctctgcag caagctctag tgcttcttct gttgtgatct
    28321 ccttggttag atcggttgct ttcacttccg tagaaccagt agcgatagcc gttacttttg
    28381 aagtctgtgg atcgatttct acgtggactt cgatcgattc tggtgtagcg cctgattcaa
    28441 tcgctttatt catcgcttca tttttcaacg atcgtatatc ttctttactt ggcgaaggga
    28501 tgatacgttc tacaacatct cggaccattg caagtgctac accaatagaa gaaatcactt
    28561 cggcgttttc aggaatcgaa tatttcacac ccattttatt actaaagtaa gtaatcaatg
    28621 aggcagcgcc gccccctaca cctacaagag aaatctgatc tttctccaag tgatacttgt
    28681 ctgccaattc taaaatcacc ggttcaatct tagcatagga tttttccatg atctgttctg
    28741 cgatgtcttc aaccgtcgta tgacaataat cagctaatgc ttggatggct tttcgtgcag
    28801 atgggacatt tccataagaa aaatgttctt cttgcactaa tccaaggaca ttggctgcac
    28861 atgtatttgt aatagtcact tcttctccgt cttccatcac taccttgacg taatcagcag
    28921 ggtctccttc tttaggagag aaaaattcaa ccttaggacc tttgattttt tctgtctccg
    28981 taaatactgc ataatctaga ccggcaatat gtgcagaacg tggaccgaca tcgatgattc
    29041 ctgactgatt agcccgtacc atcgaaccgc ctgccacacc tagaacccga acatctaatg
    29101 aagagatata tgttgggtgg ccggtggcca cctacaattg aataatcgat tgctggacgt
    29161 ccatttttaa tgaccccgat attggttgtt gttccgccta cttcaaaata aacaccatta
    29221 gacgctctca agtacatcaa agagcccatg actgatgctg ctggaccgga aagcatggtt
    29281 aaaacaggtc gttttttcat ttcattgatt tccattactc cgccgtctcc gcgcataatc
    29341 atcaaagaaa cattgacccc tgcttctcgt acggaatctt ctgtagaggt tgccgtatct
    29401 agcatttttg gtaaaataga tgcattgatt gctgctgtcc gagttcttct tgtcaatcca
    29461 tataattttg tgatgtcaga agccatcgtt gtagggatcg attttaccga tgctgcttca
    29521 taaacaactc gttctggttc cccattatct actccaaatg ccatagaaga aaccaagacc
    29581 tccgctcttt ctctttctaa agaagaaatc gtttctgaaa cacggtctac atttaagtgt
    29641 ttgacaggta agaatgcatt gacaatctct atttttttct tattccctaa atcgatatcg
    29701 ttcaatctag tttgtcgttt tgctaaaaaa ccttctaatc caccttttgc catcccgatt
    29761 acgccgactt ttgctacgtc tccttcaatc agtgcattag tcgcttgtgt ggtagaatgt
    29821 gcaacaaaca caacatcttc tggactgata ttattttcca gcaaacaatt ttgaaaagac
    29881 tgaacgacac ctgcggctac tccacggaca tcatcgtggg ttgttttcac tgaagatttt
    29941 ccgatgattt cgtgcgtcgc attatcgatt gcgactgctt tcgtatgtgt accgccaaca
    30001 tcaattccca ttcgcacaaa acgtttcatt ttcttttcct ccattcatct aatcgttttt
    30061 atcgacgttt tgtttactag gcgttcccgt acaataagaa cgtgatcagg cataagatcg
    30121 ctccgatgat ccaaccagtt gggatggatt tcttcatata ttctcgagaa gttacttttg
    30181 tataacctaa tccccaagca acccaagatt gtgtaatatc taaatgctga ggagcaatcg
    30241 ttgtgattgc aaataacggg aacaaaaagg ctggcgacat cgttggatta acagctaata
    30301 cgacagctaa aatagctgag cctgaaccga ctagattcat tggaccgcgg aaaaatccta
    30361 gtggtgtcaa tatagcaaat acgattgcca agactaatgg tgattgcggt atccaatctc
    30421 caaaaatagc tgaaaaataa ggagaagcat acgcagctga attattgaac atcgctaagg
    30481 tcatcaagaa accaaccatt ggcgcaacat ctactgcgcc atctgtaaat aatttcgcaa
    30541 actgacgaca gatttcttta taacctccgc gcaattttcc agtaaacagc aatgcccaga
    30601 tacctgctag aataaaacct aagatgattg gaagatctaa aagaacgacc cctaaaactg
    30661 gtaataatac ggctaaccat gagatcattg gtgcgtcgcc accttcagct ggtacgtttg
    30721 ctgccattgc atagcgtttc tttttgttca ttgatatatt agcgaccgtt agtaccacaa
    30781 ctaagcttac aatcatccca atcataccaa tttggaaata gtcattataa gtatagcttt
    30841 cagccgctgg attgaaacca gcataaatcg tttgatattg tttgaaattg acgatattag
    30901 caaagattcc agccataatc gagcccataa atgagaacag tgcaaccggt actgaaatac
    30961 ctaatgacat caagattggc aacacaataa ctgcaataga aatcactggt ccgattcctg
    31021 tcatcgacat gaatataaca gcggttacaa tacatagtaa gctcatcgtg attcttggct
    31081 tgtcccctcc aagttcaact acctttcgaa tcagggtagc tgcgattccg ctatctacta
    31141 gaacacgccc gaaaaaggca ccaaagaaga catttaccaa gatcgatttg gcgtactcag
    31201 ctggccccgt cgtatagata tgcgtcaaca catcaattac tccttgccct tccatcgccg
    31261 ggtttggtga aaacgtgttt ccgactagcg ctaatcccat ccatacagta gccatgatgg
    31321 caaagccgac catcaagttg tagcctttta cacagtacca gaccatgaaa aagaatgaga
    31381 taactaacaa aataccaata ataatatcac tcatgttatt cctccgtcca ttttgttttt
    31441 ctgataagca aactaatata tcagtcaaac tcattctaac ttatgtagtt agcgctttca
    31501 ttaaagggtg accataaatg ttcagttttc aattaaaaaa ccttaattat gctattttag
    31561 acttatacgt tattgtcctg tttcatttga tggaggattg taaataaaaa aagaggaaag
    31621 aacataactt ttcgttatct tctttcctct ttataattgt ttagcttatt tagccaaagc
    31681 ttcttttgct tggtcagcca atgcagtaaa tgctgctgca tcgttaacag ccaagtcagc
    31741 taacatttta cggttgatgt cgatttcagc aactttcaaa ccgtgcatta attttgagta
    31801 gctcaagcca ttcatacgag ctgctgcgtt gatacgagca atccacaatt tacggaagtc
    31861 gcgtttcttt tgacgacgat cgcgatatgc gtagttgtat gaattcatta cttgttcttt
    31921 tgctgtttta aataaagtgt gttttgaacc gtagtaacct tttgctaatt ttagcactct
    31981 tttacgacgt ttacgagtta ctgttccacc tttaacacgt gccatgtata attcctccta
    32041 ataaaaataa atcttcagat tctgttattt gtacttctta tttcattttt gctagttgtt
    32101 ggcgaatacg tttgaagtcg ccactagaaa ccatgcttgc tttacgcaat tgacggcgtt
    32161 gtttttttgt tttgccgtgg aaacggtgac ttgtaaacgc gcggaagcgt ttcaatccgc
    32221 ctttaccagt acgtttgaaa cgttttgctg atccgcggtg tgttttttgt tttggcatga
    32281 ctatatttcc tcctcaaaat ctttcgttat ccgactatcg gctgtccaac agccagttag
    32341 tcattcaaat tacttactgt cgtttttcgg tgccagcgtc aagaacatgc tgcgtccgtc
    32401 cattttcgct ttttgttcca ctgttgcaat atccgcagtt tcttcagcta agcgattcaa
    32461 gactttttga ccaatttctt tatgggtaat ggcacggcct ttgaaacgga tagaagcttt
    32521 cactttatcg cccttttcca agaacttacg tgcattacga agttttgtat tgaagtcatt
    32581 caagtcgatc gtaggactta agcgaacttc ttttacattg atcacttttt gttttttacg
    32641 cgcttcgcgg tctttctttt gttgttcgaa acggtattta ccgtagtcca tgattcgcgc
    32701 aactggtggt ttcgcaccag gggcaactaa cacaagatcc aagtttgctt gttctgcaat
    32761 attcaatgct tctgcttttg tcttaactcc taattgctca ccatctgaac cgatcaatcg
    32821 taactctcgt gcacgaatgc cgtcgttaac catcatatcc tttgctatgg tcattcacct
    32881 ccaaatatta tgagagaaag aaaagcttac cgaataaacg gcaataaaaa aacgagttct
    32941 cttacagaac ccgcgcgtac ttcacctaat agaaccagtg aaaactatct agcccagtga
    33001 cattatcaac taaggcgaga agcgggtgct tctgctttta tttctcaacc atcatagtat
    33061 agcaaaaact aatctttttg tcaatgtttt tcatacagtt tgtcttcctt ttctgaaaat
    33121 gattagatta gcagactttc tagcagtgat tcccgcttct ttgtgctata ctaaagaaaa
    33181 acgaggtgaa cccacatgaa aaaaatcgaa cctattccac cttctcttcc tcttcttaca
    33241 aagggagagt tttatttaga agatgaggag atcttctctg gtcttctgat caacgggggt
    33301 gaccaaagct atctcgatgc caaaaatatg gtattaagag agagtcatat ccaaaaactt
    33361 acgatgcaaa aaacagtttt acgtcatttt gaatgcagta atgtcatttt tgaaaaatgt
    33421 gatttttcca atctggagtg gattggtggc agtttccacc aagtcgtgtt tcatcaatgt
    33481 aaattaacag gtacgaattt tgccgaaagt tatcttcgag actgtacttt cactgattgt
    33541 attgcttcga tggcttcctt tagtagtaca aacttgaaag ctgtctcctt cgatcattgt
    33601 caattagaag acagcgaatt ttatgaggtc acttggaaaa accttttttt gtctgacaat
    33661 cagttgaccg gttcgaactg gtttcgaact tctctgaagg gattagactt tacgactaat
    33721 ttcttcacag caatcgcttt atctcaagat tctttggcgg gactaatcgt caaccaagag
    33781 caagcacttg tgatcgccca agcccttggt ttgcagatca aagactagat caacgaatcc
    33841 gccgccacag tgcaataagc atccaaatag ataagaccaa actgatgatc aaggcgattc
    33901 cccatccgaa aacggaatgg gtaaagggta actggagatt cattccgaag aatcctgtca
    33961 caatagttgg aacggtcaag atcagcgacc agaccgtcaa aaatttcatc gtgtcattca
    34021 agttgttatt cagcaaatta ttataagtgc cagagagctg gtctaaaatc tgcgaagcta
    34081 agttcgtcat ttcaactgct tgtcgtgctt cgatcagcgc atcgtccaac tcttcttttt
    34141 ccttttctga caacttgcga taaatagcca atgccttgat ttgttctaaa agtactacat
    34201 tttgttttgt tcctgtaact aagtaaacca aaccgatctc taaatctgaa agttgcagca
    34261 gattcttgtt cgttgttttt tctcttaatt tcagattaag ccgctgacgt tcactattca
    34321 cttcctcgat taaaggaaaa aaggaatcag aaatcaaaaa caatgtacga aacaataaac
    34381 tgtatacact catgtctggc attcgttcca aaagcgatcg aattagtcga atcacgtact
    34441 cggtattcgg cgtggtaaat gtaaacaaac cgtcttcttt taaaataaaa gcgataggac
    34501 tagtttcata atgattatcg actttttgct ggtgcggaac atttgataca agcagtaacg
    34561 cttcatcaaa agaatcgtac tctacgcgcg cccgttcatt tttatctaga gaataagtca
    34621 gcatctcgtc actaatgcca tattcttctt ttaagttttt aacagctagc acatcgtttt
    34681 gctgtacatt gatccaaaaa ttacggtctt gattaaaata gtgtttttcc cgcatactct
    34741 atcctcctga catttgtttc cagtataaag aaaaaagtcg ctcaaataaa ggtttaccct
    34801 ttatttgagc aactgtaaat caaatggcta ctttggtttg gcgaatctct gctaattttt
    34861 cttcgatcat tttcaagact tcttcttttg cttgaggatc ttccacaaaa ttatagcggt
    34921 ctccatcgat ttggattttt ggactttctt tgtattcttc ataccattga tcgtaacgtc
    34981 tgttcaattc tttgtaataa tcgtatagac ttggatcaaa ggacaattgt tcatacgaac
    35041 gaccacgttt ttcgatacgc tccaacatcg tatcaaaaga tacacgaata tgaactaata
    35101 aatccggatg ttttttatgg gcagcatagg gaagttcttc catcatgttt tccagcagtt
    35161 catcatacac acgaacttct gtttctgttg ctcttcctag atctgcattt agatggaaaa
    35221 gcagtgaatc ttcataaatc gaacggtcca atacattatt gtcatctttc attgcttgtt
    35281 tgatgcttgc aaaacgttta ttcaaaaaat aaatttgcag caaaaaagca tactgttcag
    35341 ggtttgcata aaataagggc aagacttcat tatcatcaat cgattcataa aatgcctgac
    35401 tatcaaagtg ttcagccatc atttctgtta aacttgattt tccggcacca attgtacctg
    35461 ctaaaacgat cacgctcatt tacctccagc tcacttcatc actaaatatt gtgtttaact
    35521 ccaacctttt taaatatacc cccaatatct agtagtgtca attgtatttt tttctagtca
    35581 aagaagaaaa aaagtcaaaa aattcttaag aaaaaagtgt tttttcttta gaaaacgtat
    35641 tcttagtttt acttctgaga tggttttagt aaaataaagg aggaatgttt tttgagaccc
    35701 ttagtggaca aaaaaattcg tgaagcagcg caactcgttt tgggcgcttt attttttgct
    35761 taaaaatcac ttttacgtga gaaggagtta gattatggca aactatggcc aaggagaatc
    35821 aagcggaaag atcatattga tgggcgagca cgcggttgtt tatggagaac cagcgattgc
    35881 ctttcctttc tatgcaacaa aagtcaccgc attccttgaa gagctggatg caatggacga
    35941 tcaactggtt tcttcctact attcaggaaa tttagccgaa gctcctcatg cattaaaaaa
    36001 tatcaaaaaa ttattcattc acttaaaaaa acagcatgac atccaaaaaa acttgcaact
    36061 gaccattgaa agcacgattc ctgctgaacg tggaatggga tcaagcgctg cagtcgccac
    36121 agcagtcact cgtgcttttt atgattactt agcatttcct ttgtctcgtg aaatactatt
    36181 agaaaatgtc cagctttcgg aaaaaatcgc ccatggtaat cctagtggaa tcgatgcagc
    36241 cgctactagc agcttgcagc cgatttattt tacaaaaggg catcctttcg actacttttc
    36301 tttgaacatc gatgcttttt tgattgtcgc tgatacagga atcaaaggac aaacaagaga
    36361 agccgtcaaa gatgtcgctc acctctttga aacccagcct catgaaactg gacaaatgat
    36421 ccaaaaatta ggatacttga cgaagcaagc aaaacaagca atcattgaaa attcaccaga
    36481 aacgttggca cagacaatgg atgaatcaca atcacttctg gaaaagctga caatcagcaa
    36541 tgattttctt aatctattga tccaaacagc aaaagatacc ggggcattgg gtgccaaatt
    36601 aactggcggt ggacgcggtg gctgtatgat tgcattagca caaacaaaaa caaaagccca
    36661 agaaatcagt caagcacttg aagatgcggg tgctgctgaa acttggatac aaggattagg
    36721 agtacatacc tatgtttaaa ggcaaagcac gcgcatatac caacattgct ctaatcaaat
    36781 attggggtaa gaaaaatgaa gaactcatcc ttccaatgaa caacagcctt tcgttaacat
    36841 tggatgcatt ttatacagag acagaagtca tcttttctga tagctatatg gtagatgaat
    36901 tttatctaga tggcaccttg caagacgaaa aagcaacaaa aaaagtcagt cagtttcttg
    36961 acctttttcg taaagaagcc ggcctctcac taaaagcttc agtaatcagt cagaatttcg
    37021 ttcctaccgc agctggatta gcctcctctg ccagcgggct agctgcttta gcaggcgctt
    37081 gcaatactgc tcttaagctt ggattagatg atctctctct ttcaagattt gctcgacgcg
    37141 ggtctggttc agcttgccga agtattttcg gtggtttcgt cgaatgggaa aaaggccatg
    37201 acgacttaag ttcttacgct aagccagtcc cttccgattc tttcgaagac gatttagcaa
    37261 tggttttcgt tttgatcaac gaccagaaaa aagaagtgtc cagcagaaat gggatgcgtc
    37321 ggacagtcga aacatccagt ttttatcaag gctggttaga ttccgttgaa ggggatctat
    37381 atcaattgaa acaagcaatc aaaacaaaag atttccaact tctcggagaa acgatggaaa
    37441 gaaacggact aaaaatgcat ggaacgactt tagctgccca gcctccattc acttactggt
    37501 ctcctgacag cttaaaagcg atggatgcgg tgcgacaatt gagaaagcaa ggcattccat
    37561 gctactttac gatggatgct ggccctaatg tcaaagtttt agtggaaaac agccatttat
    37621 ctgaggtaca agaaacattt accaaattat ttagcaaaga acaagtaatt actgcacatg
    37681 ctggtccagg aattgcgatt attgaataaa gggagatttt tatgattgaa gtatctgcac
    37741 caggcaaact ctatattgcc ggagaatatg cagttgttga aacaggccat ccagcagtta
    37801 tcgctgcagt cgatcaattc gtgacagtca ctgtagaatc tgcacgaaaa gtcggaagta
    37861 tccaatctgc acaatatagt gggatgcctg tacgttggac aagacgcaac ggagaattag
    37921 ttttagatat tcgggaaaat ccttttcatt atatccttgc tgctattcgc ttgactgaaa
    37981 agtatgcaca agaaaaaaac attcttttat ccttttatga tctgaaagta acaagtgagt
    38041 tagacagttc aaatggccgg aaatatggat tgggttctag cggtgccgtg accgttgcaa
    38101 cggtcaaagc cttgaatgtt ttttacgcgt tgaatttatc tcagttggag attttcaaga
    38161 ttgcagcact agccaattta gcagttcaag ataatggttc ctgcggcgac atcgctgcta
    38221 gctgttatgg tggctggatc gctttctcaa ccttcgacca tccttggctc caagaacaag
    38281 aaactcagca ttctatcagt gagttacttg ccctggattg gccaggtcta tccattgagc
    38341 cattgattgc tcctgaagat ttacgtttat tgattggttg gacgggtagc cctgcctcta
    38401 cttctgattt ggtcgatcaa gttcaccgtt cgagagaaga taaaatggtg gcttatcagc
    38461 ttttcttaaa aaatagtaca gaatgtgtca acgaaatgat caaagggttt aaagaaaata
    38521 atgtaacgtt gatccaacag atgattcgaa aaaaccgaca attactgcat gatttatctg
    38581 caatcactgg ggtcgtcatc gaaacgcctg ctttgaacaa attgtgtaat ttagctgaac
    38641 agtatgaagg agccgcaaaa tcttctggtg caggtggggg cgattgcgga atcgtaattg
    38701 ttgaccagaa atctggcatt cttcctttaa tgagtgcatg ggaaaaagca gaaatcactc
    38761 cactgccgtt acatgtctat agcgatcaaa gaaaggaaaa ccgatgaatc gaaaagacga
    38821 acatgtttca ctagctaaag cctttcatga taaacaaaaa aacgaatttg acttcgtacg
    38881 gatcatccat aaccctttgc cgcaaatagc agtttctgat gtcgatctaa gtacacaggc
    38941 agttgggttt acactaagca gcccatttta tatcaatgcg atgactggcg gaagcgaaaa
    39001 aacaaaaaaa atcaaccaag atcttgcaat cgtcgcaaga gaagcagatt tgatgattgc
    39061 cactggttca gtcagcgctg ccttgaaagt cccttcttta gccgatactt atacgattat
    39121 gcgacaagaa tatcctcacg ggaaaatcat tgccaacatc ggtgcaggga cttctgtcga
    39181 aagagccaaa gaagctatcc gattgtttca cgcagatgcc ttacagattc atttgaatgc
    39241 acctcaagag ttggttatgc ctgagggaga ccgtgatttt accaattgga aagtacttat
    39301 tcaagaaact caaacagcca ttgacgtccc cctcatcgta aaagaagtcg gttttggcat
    39361 gacaagagaa acgctcaatg atctagctgc tttaggagtt catacagttg atatcagcgg
    39421 tcgaagcgga acaagcttca cccagatcga aaacgcccgt cgctccaagc gggaactgag
    39481 ttatttagct gactgggggc aatcgacagt ctcttcattg cttgaagcaa atgaagcaga
    39541 cacttctatg gaaatcctag cctccggagg tatccgcaat gcctatgaca tatttaaagc
    39601 cctttgtctc ggcgcaaatg ccgtgggtac ttcaggaacc gtactgacgc atctgatgaa
    39661 tcacggcgta gaagaaacta ttatactgat gaagcaatgg caagaagagc ttcgtctgct
    39721 ttatactatg gtcggcgcaa cgaataccgc ggccctacac caacaatctc tgatcttttc
    39781 cggaccagtg aaggattggt gcgaagcaag agggatcgac ttagtgaagt atggaagacg
    39841 cacagaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta
    39901 caaacggcgg aagtaaaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa
    39961 aagcaatttt cgtgaattcc ttcttatttc ttggagttaa atgcttctgt cccagcctct
    40021 tttttcgaat aaatgatgtt taatcagctg tccttcggta ttcgttcaat ccgctgattt
    40081 cacaacctct ccactaaaca gtgtactaaa gctcttttaa ggttgttttc cgatataggc
    40141 aagtatgcct ccgtccacat acaagacatg gccgttaacg aaatcagatg cgctagaagc
    40201 caagaagaca gatggtccag ccaaatcgat tggctcgccc cagcgtgctg ctggcgtacg
    40261 tccaacgata aattgatcga atggatgacg ttcaccgttt tcttgtgttt cgcgtaatgg
    40321 agcagtttgc ggtgtagcaa tataacctgg tccaattcca ttacattgga tattgtattg
    40381 accgtattca gaagcgatgt ttttcgtcag catttttaat ccgccttttg ccgcagcata
    40441 agcactgacc gtttcgcgtc ctaattcact catcatggag cagatattga tgattttacc
    40501 gccgcctttt tcgatcatat ccggaataac tgcttttgaa acgatgaatg gggcatttaa
    40561 atccacgtcg attacttggc ggaagtctgc cgcatccatt tcgatcatcg gtgtccgttt
    40621 gatgatccct gcattgttga ctagaatatc aactgaacct acatcttctt tgatctgttg
    40681 aaccatcgct tgaaccgctt cttcatcggt cacatcgcag acataacctt ttgcatcgat
    40741 gcctgcttct ttataatgcg ctataccttc atcaactgat tcttgattca agttattaaa
    40801 tacgattttt gctcctgctg tagctaaaga gcgtgcaatc tcaaatccaa taccatagac
    40861 agcaccggtg actaatgcta cttttccatc taaacgaaac atatccatac taaattccat
    40921 cattttctct cccttatgct tattttaatt gatccatttg caccatatcc atgtctgtat
    40981 aggtgatatt ttctccgcac attgcccaga tgaatgagta attgcttgta cctacacctg
    41041 aatggatcga ccagcttggc gaaataatgg cttgttcatt gtctacaact aaatgttttg
    41101 tttcatctgg tttgcccatc atgtggaaca cacgtgtatc ttcattggca taatcaaagt
    41161 agacataagc ttccatacga cgttcatgtg tatgacaagg catcgtattc caagcgcttc
    41221 ctggttctaa aatcgtataa cccatttgta attgacagct ttcgcataca tttggatgga
    41281 tgtattggta gattttacgt tcattcagtg tcaggccttc accagtctcc attggtttta
    41341 cttggtcgat actgattttt acatttggat atttatgatg agctggaaca gaactaatat
    41401 agaatttagc tgggttttca gcatcttgag aagaaaatac aacatgtcgt gtttcttttc
    41461 cgatatagta tccgtcttgt tttttcattt cttctttttg cccatcgatc tcgatgaatc
    41521 ctggtccacc gatattgatc acacctagtt cacgacgctc taagaagtaa tcaacaccta
    41581 gttctttgtc taatgtgatt tctaattctt tttcagtagg tgtcactcca ccaaagatca
    41641 ttcgatcgtt gtgcgtataa gtcaaactga ttttccctgg ttcaaatacc ttttctacta
    41701 aaaattcttt tctcaattgt tccgttgaat aatgacggat atcttctgga ctgtgtgtat
    41761 aacgtgtttc catttcttgc attttcttct actccttcta tcgaatgatt tttccagagc
    41821 cgcatgctaa aaattgtgcg acttcttctt gactaaattg gttgcagtcc ccatggatcg
    41881 tatgcttcaa ggcagaagct gccgtagcaa aatcaatgat ttcttgcgga gacatattgg
    41941 ataaaatccc atggagcacg ccacctgcaa aagcatctcc gccacctact cgatccacga
    42001 ttggggtgat tctatggact tgggattcca catattcatg gttcatccac aatgtcccct
    42061 tcaattcatt ttcacttgct gaatgaacgg tacgcttggt cgaataaaac acctgaatat
    42121 tcgggaactt ttcctgcatt ttttgataat aataaattag aggttgttct tctgcttctg
    42181 gcgctttctc gatacctaac aaataaagag catccatttt tccagctgag cagatatcta
    42241 ctaaaggtaa aagctgatgg attacttcgc tggcttcttg ctgtgtccat aattttccac
    42301 gatagttgat atcgaagctg atcaggcagc cagctttttt tgcagcttct atcacctgtt
    42361 tcgtcatttt ttgccatttt ttagacaaag ctggggtgat tcctgaaaca tgaaatatat
    42421 ctattccttg gaataactcc tctagcgacc attccaaatg atccatttca gcaaaacttg
    42481 atccggcacg atcatagatc actgaggcgg cgcgttcgcc actaccagtt tccatataat
    42541 aagtacctag tcttgatcca ccagataata cctgtttcgt atctactcca taacattgca
    42601 agtgcttttt gactgctttt cccaatgcgt tatcaggtac ttttgtagca aaaatcgctt
    42661 catgtccgta attagctaaa gaaattgcta cgtttgcttc ccctccgcca taatgggcag
    42721 cgaatcgttc acttgaatcg atacgggttc cctgctctgt ggacaatcgc aacatgattt
    42781 ctccgagtgt cactactttt cccataagca gctacctctt gatttctttc atttttgctg
    42841 catactgttg cgcgacttcc gttactttgt caaaatctcc tgtagctgcg ggtgctaaaa
    42901 ggttcccacc tactccgact gttacgacac cagcatcgaa ccactctttc atattgtcca
    42961 gactcacacc gccagttggc atgatattga cttgaggcat cggcgccttg aaggcagaaa
    43021 tgatacttgg tccataagcg cttccaggaa atagtttgac gatatctacc ccgcttttca
    43081 gcgctgtttt gatctcggta atagtcatac atcctggtaa gtaaggaatt tgatacagat
    43141 tgcacatctc tgccgtttct tgatcaaagg aagggctaac aatatactct gcgccagcta
    43201 agatagccaa gcgagctgtg acagcgtcta atactgtgcc tgcgccaatc actatttctg
    43261 gttggtcttt gtagaatgac aaaagttctt tgattacttg atctgcttga gggactgtaa
    43321 aagtcaactc aataccagtt agaccacctt tgatgattgc gtggcaagca ttcaaagctt
    43381 cttctttgct ttttccgcgt accaccgcaa tcactccggc gtttttcaat cgagataaaa
    43441 tatcaatttt tttcatcttc tccacctatt tcctatttag aaattttatt ttataacttg
    43501 gaaatctata cccatattat acggcagaaa agaaaaattg caaacgcttt tttcattatt
    43561 tttgaattct ttgctcgatt tcgctttttg tttgcttgag ggcactgatt atttgttctt
    43621 ttgtctcatc tgttaaacga tatttcggca tacttacact aaatgcacca atgatttgtt
    43681 cgtttttcac gattgaggct cctatacaaa aaatatcacg ttcgatttct tcatcgtcaa
    43741 atgcgatgtg ggtttctttt accgttttga tttccttttt caaccgtaat gcattggtga
    43801 tcgtatattc tgtgtaaggg atcaacggat gcttttcaag ataatcagtg tactgctctt
    43861 cactgaattc tgctaatacg gctttgccca tcgcagaatt gtataatggt cgggtgattc
    43921 cgatttttga agacatgcgg atcgtttgat gttttggatc tagtttgttc acgtacaaga
    43981 tctcattgtt gtccaatacc cctaagtgga tagtctcatc gatcttttgc tgcagctgtt
    44041 ctaaaaacgg taaagtcaac tctaccaaat cgatttgttc aatgttttta ttcgcgtagc
    44101 gaataagctt tgcacctaaa cgatagtttt tctctgaatt tttatttacg tagccgatca
    44161 tcaacaaagt atctagtatt ttcaagactg tagaagaggt cattcccaca ccctttgcga
    44221 tcgtctgcaa agagacatct tggttttccg ctaaatagtc tagtatttta gaggctttga
    44281 tcaatacagt tccataaggc tttttatttt ccatataata ttctcctatt tctttataag
    44341 aaaaattata gcggaaatac catcaattta aaagagatat ccagatataa actaccattt
    44401 ctctttacag gcaatttaat gttgaagatc cgcttcgttt ttacatcaaa ctttgatata
    44461 aagcaatgat ttcttctact gtcgtttctc ttggatttcc tggtgtgcat acatctcgca
    44521 aagcatcttc tgcaattgct ggaatatctg cttcttttac acctaattca gaaatggttt
    44581 ctgggattcc aaccgctttg ctcaaccgat cgatctcacc acaagccgct tctcttacat
    44641 cttctaaaga catttcagct gctcctttaa tccctagaac aagagcgatc tcacggtact
    44701 tttctccagt atattctttg ttatatttca tgacagttgg caaaagtgct gcacacgcta
    44761 cgccatgagg aatgttgtac catgcactta acgggtgagc catcccgtgt accagtccta
    44821 aaccgacatt tgagaagccc attcccgcaa tatactgtcc taatgccatt ttttctcgcc
    44881 cattttgatc gccatctaca gaagcttcca aagaatggcc gatgatttcg attgctttta
    44941 aatgcagcat atcagtcatt tcccaagcgc cttttgtgat aaacccttca atagcatgcg
    45001 tcatagcatc catacctgtt gatgcagcca attttttcgg cattcccatc atcatatcgc
    45061 tgtcgatgaa cgcgacgatt gggatatcat gaggatcaac acaaacaaat tttcggtgat
    45121 ttacttcatc tgtgatgacg tagttgatcg ttacttctgc tgctgttcca gaagtcgttg
    45181 gtatagctaa tataggtaaa catggatttt tcgtatcagc aacaccttct aaactaatga
    45241 cgtctgaaaa ctctggattc gtcaaaataa tcccaatggc ttttgccgta tcgattggcg
    45301 aacctccacc gattgcgatc aaacagtctg cctctgcctc tttaacaaaa gccactccat
    45361 cttttacatt ttggatcgtt ggattaggta cgatcccgtc gtataaagca taagcgattg
    45421 ctgctttatc tagaagttct gttacttttg ttgctatacc gtgctcgatc aatcctttgt
    45481 cagtaatgac agctgctttg ccgaatcctc gctgctgaaa ttcagggacg atcgactcaa
    45541 tcgctccttt tccaaaatac gatgtttcat ttaaaatcat tcgattactc attttctatt
    45601 cctcctaatt tgtattattt ttcacaataa aaacgaaaga accccaagca accggttgcc
    45661 cagttgcttg ttgctacagt tcaaagactg gcatcaattc ccaactgact ggagaggcat
    45721 ctggatttgt ctccatgata tcttccatgt acttccacca tttttgattg atagatgtat
    45781 ttgccatttt ttcccataac ttttcatctt cgatcactaa gtaaccaaat aacaaacttg
    45841 tactcggatc aagatagatc gaatagtcga tgaccccgtg ttcacgaagt gctgtacgca
    45901 tttctggcca aagttcatca tgtctttttt tgtattcttc ttgtttttct gggtaaactt
    45961 tcatgcaaaa agcttttttc accatgtcag acacctgctt tcgtatgaac ttcctccaaa
    46021 taacctgctt ttggagtgac accaaacgca tctgctaaat gccacaggtt ttcgtccgtg
    46081 attgtttgca agattggtcc ttgcgctttg acgtacgtat agacttctgc tgccttttct
    46141 gctgtctcga tcaaaccaaa gacttcatcc atgtcttttc ctgacccgta gattccatgt
    46201 tgtggccata aaaccaatcg agtttctttc attttttcag ctgttgcttc cccaatctca
    46261 tttgttcccg gaaccatcca cggaatgatg gaaattcctt ctggaaaaac aactaagcat
    46321 tccgtacaca tttgccatag cgtacgacta aaggaacgtt cgtctaattc atgcgtaaaa
    46381 ctcatcgcta atagatgact agcatggcaa tgcataacga tccgattatc tgggtctact
    46441 tctaaacggg cgatatgact catgaaatga cttggcaact cgcttgtagg aaggcattcg
    46501 ttttccagcc cccacaaaag ttccagtgtt ttgccatctt cagcaactcg aacgattcca
    46561 agattctcgg caggttcgct cgctacattt ttaaaatatc ttcctgaacc agttacaata
    46621 aaatagcatc ctgctaaacg gctggcatca aaaatcatcg agatgcggcg gatcactttt
    46681 tcaggatcca agaacggtgt gatctcttct tcttttagta aataagaaat attcccgcca
    46741 tttctttcat cccatcccaa gcgataaaga ttcgacgtcg tttcgatcat ttctttcaca
    46801 taaggcgctt gtaaaatatc tatttttttc aatatagcca cactcctatt ttcttaattc
    46861 caacacgtct ttttgatatt cctggacttc ttccagccaa tccaaaccaa ctggaacttg
    46921 atttttgtaa cagaaataat tccatacatc ggcatacggg aaatctttca attcttccgt
    46981 ataagccatt cttgaagtaa agtcaaaagc cagctccatt tctttcaatc gctcaactgg
    47041 ttccagcata gctttcagca gtgctttttg tgtatttctc gtaccgatga cccaagcagc
    47101 gatacggttg atcgttgcat caaagaaatc cagaccgata tttgtttttt ccaacaattc
    47161 gttacggact aattctttag cgatttcctg caattcatca tccatcaaaa ccacatggtc
    47221 tgaatcccaa cgcactggac gggaaacatg caacatgatt cctttgctga ataaagctaa
    47281 tgaagataat ttattggaaa tcacttctgt tggatgaaaa tgtccagcat ctagacaaac
    47341 aagtttgtca cgagtcaacc cgtaacccat ataaaattca tgggaaccga ctgtataagc
    47401 ttcagcgcct aaaccaaata gtttgctttc tactgcatct tgtacatacc gttcatctaa
    47461 ctcttctgta aaaatttcat cgagtgattc cattaaacgt tcccgtgggg taaaacgatc
    47521 aatcggatta tctttcatcc catcaggtac ccaaaagtta ttgatacttg tttgcccagt
    47581 ttctttccca aagtactccg cgattttgcg gcttcttttc ccgtgttcga tccagtattc
    47641 acgaacttct ttatctggat gagccaatgt aaagccgtct ttcatcattg gatgcgaaaa
    47701 gaaagtcgga ttgaagtcaa gaccgatttc ttcttttttt gcccactcta cccatttttc
    47761 aaaatgtttc ggctcaattt catttagatc gacagattct tctgtatcca aatagatagc
    47821 atgaaggttc aatttgtgtt tgcccggtat caacgaataa gccttctcca gatcttgtct
    47881 aagctcttca ggtgttcgtg cggctcctgg aaaattccct gtcgccatga ttccaccggt
    47941 caattcgcca tccggtgtca agaaaccttt gacatcatct ccttgccagc aatgcataga
    48001 aattttgatg tcctgtatct tttctagtac agcatctgta tctacaccga tagttgcata
    48061 tttttctttt gcttgttcgt aatttctttc aatcgtgttc atacgattac tcctttgatt
    48121 ttattcacgt accattccat cgtgttttgc ttattttcat ctgggtaaaa agtttcacat
    48181 ggaaacgact gtttgattac atttcttgct tgttctatat tcgaaaactg acctgtactg
    48241 agcatttgca tggcaacatt cccgattgct gtggcttcac taggtcctgc ttctacaatg
    48301 attccggcat aatctgctgt caattgattc agtagacgat tattcgatcc gccccctacg
    48361 atgtgcagct tttccaattt cgttccagtt aagtgttcta ctttgatcag ctcttgtgcg
    48421 taacaaagag caagattatc atacacacaa cgagcgatag ctcccgatga gacagggact
    48481 ggctgctctg tttcaaaaca gtattgctga atctcttcta tcatatttgg gggattcaaa
    48541 aatcgagggt cattgatttc catcacttgc tgcagcggtt tttcttttgc agcaagctct
    48601 gccaattccg cataactgta ctcgtactct tgcattcggg caacttcctg gatcaaccac
    48661 atccccatga tgtttttcaa aaaacgcacc gtgttatggg caccccattc attcgtataa
    48721 ttttcagaaa aagcattgcg agaaacattg gcgatctttg tttcaatccc taaaagcgac
    48781 catgtcccac tgctgatata accccaacgt tctccttgac ctggcgttcc taatacagct
    48841 gacgccgtat catgacttgc tactgtgata aaggtcacat ctggcaaatc atattttgaa
    48901 aattgttctt tttgcagatc tcctagtatc gttcccggct ctgtcaatgg tggaaataat
    48961 tccttcgaga caccgatttt ttcaagaagt tctatttccc attcttttgt ccctgcattc
    49021 agcagctgca tagtagatgc attagttttc tccgtcacca tgttaccagt aaagacatac
    49081 cctaaataat caggtatcag taacaattta tgtgcttttg ccaaattttc tttttcttca
    49141 gcaaacaatt ggaacaaggt attgaaaggc tggatctgaa tccctgtctg ctcatacaac
    49201 ttatctagag aatagatttc agaaaactgt tctactgctc cattggtacg cttgtcccga
    49261 taagcaatcg gatcatttat ccgatcccct tgttcatcaa tcagacagta atcgactgcc
    49321 catgtatcga tccccgcaaa aaggcgatca atccctgtct gctttaattt ttcaaatcca
    49381 atcaaaatct ctttgataag ataatcgatc ttccagcgat cgtgaccgtc tttgttccga
    49441 aagccgtttt tgaaccggtg tacttcttcc aagatcaaag aaccttttgc atccctcgta
    49501 cttttcatta gtcgtccgct tgatgcaccg atatcgatgg caacaaatgt tggattcatt
    49561 tctccacctc ttttacttta ttgttgatta gcactttatt aataaagcgt tatcatttat
    49621 tgacaatgct atcataatac agaatcttat attttgcttc acactatttt ggtatataat
    49681 tgcattatct tgacaagttg ggagtgttta catggattac tgggaaaaag ccaaccactc
    49741 atggtcggaa gactcaaaaa gagtgatctt gacgcctaca caaagaagca ggaatttatt
    49801 tttttatatc caagaaatcg gttacttcaa agcaccaatc ccttactata ctgaacgagc
    49861 acatttacct tcttacttga taaagtttac tttgtctggc aaaggttcgc ttacatataa
    49921 tgataatcag caacagctaa aagctggaga cttatttttt attgactgcc aagaatatca
    49981 gcgttatcaa acgatcagcg aagaaccatg ggaaatggat tggatccatt tgaatggtca
    50041 gaacgtccaa tcattttatc aggagttcac aaaagacggc cataacacct tccattcaac
    50101 aggagatcca tcagaaaaca agatccacca tttgatcaca gaattgatcc acatgcaaca
    50161 aggcacgaat gcccgtaccg atttccagtc ctctgtagct atccacgagt tgctgaatga
    50221 actgattttg caaaagtatc agctagattt cgaagaagag gatattcccg cctacgttta
    50281 caaactgaag caatacttag acgaacattt caaagaaacg attacacttg atcaattaga
    50341 acaacaattc ttattgaata aatatcagct gagcaaagat ttttccaaat ttatcggttc
    50401 tccaccaatc gattatttga tcagcaaaaa actttcttac gctaaagacc ttcttcggta
    50461 tacagaattt acggttcgaa tgatttccga agaaataggg attgagaatt ttgcttactt
    50521 tagccgcctg ttcaaagcaa aaacaggact atcgccgaga gactttcgta aattcagctg
    50581 attcatataa tatgtacgtc attttttcaa aatattttga aatatataga taaaaataaa
    50641 ataaccgcag tttctgcttc tatgtaaaca acagcagcta ctgcggttat tttttagtga
    50701 tcattctcat tgttcatctt caaaatgttc ataatgaacc aactgtttct gtgtatcacg
    50761 tttcaaaaat tctttaggcg ttatgccgaa ctctctcttg aatgctttca gaaaatgcgg
    50821 ataagaagaa aaaccacttt tactatatac agcactagag ctgcggtatt ctcgcaacaa
    50881 gtgcttggca tagatcagct ttttcttcat tacatactga tgaaacgtaa atccagtgta
    50941 ctttttaaat tctcgtgtga tatggtattt gctgacaaaa aactgctttt ccatttcctc
    51001 taaagaaagc ggatgagata aattttttga gatatattgt aacatttgtt ccacacgctc
    51061 attaggaact acagcattct gttcttgcgc actctcttct ttttgtacaa cttgattgag
    51121 aaaaatcaag tattctacca gagcttgttc atattttatg tcttcaccgt aaattttttt
    51181 atcaggagga tggtcgataa atgataattt ttgcttcaat acttcctgtt ctatttgcaa
    51241 tacacgactc ctcttctctc ccattggttg aaaacaagcc gatagattag accatggcgt
    51301 ggaacgactt tctagaaaag aaggggtgac aaagatatag acacgctcga atacatctga
    51361 agattggcgg acgatacgat gcaaatcatt ggaatggatg agcagcacac ttcctgcttt
    51421 gatcgtaaat tgtcgtccgt tcaaataaaa agtcgcttct ccctttaatg tagcatggat
    51481 ctcatagaaa tcatgatgat gatagatcgt tttattttgg ctgacgacat ctttgacatg
    51541 atagatttca tactgatcag aaaccatcgt attgacttgt tcaccgctga ttttcttttg
    51601 gagcatgtgc cgcacctcct tttgttcact tatgcacaat tttattatac cacgtttttt
    51661 gtaatcaaaa agagctgctt ttatatactc ttataaaaaa gaagagacgt ggcatcttct
    51721 agccccgccc cctccattct aaatattagt taaccaacgt cttctttaca ttattcaaga
    51781 agacttcttc cataacgaat cccatcatct tttgtttctt caagaaccac atacaggtac
    51841 ggacgattct tcatgatgat ttctttgatt tttgtgtact cgatcacacc gtctcccaaa
    51901 tttaccggca cgattttttc ctgttcgaca cgaaaatctt tcaaatgaac cgcacatatc
    51961 ttttcaccaa aacgttcaaa agcttcttct accaattgga cttgttcttg ataatcacta
    52021 cttgtgatca aattggtcgg atctaaaatg attcctagat agtccgaatc tactgcttgg
    52081 atcagctgct ctacccttgc taaagaatac accggatgat tcaaacctgg ttctatcccc
    52141 accatcattt ggtatttttc tccagctttt accaagcgac ggataacgga cacagcttca
    52201 gcaaatgctt catctgtgaa attttcttcc gtatattgga tttccggcaa aacacatcca
    52261 gtttccgaag caaccatcga cgcaccaaag gaagaagcat agcgaagata ctgctcgaac
    52321 tttgtcagca actcttgtcg tatcgttaaa tctggatgaa tcatattgat atagcaactt
    52381 aaaattccta cggtcacttc ttgcttttct aaaactcgtt tgacataatt tcccatccca
    52441 gaattgatct catttgcgcc agaaggtatt tcaggaaacg aaagacctaa ggcgagctgc
    52501 agtgtatgaa tcccttgttc ttttgttttt tctgcaagat cttctatcgt ttggacttcg
    52561 gaaagatcat gtcctctaat tgtaatgttc aacataacta ttctcctaac tcagcatatt
    52621 gggtagccac atgacgattt gcgggaagta agtaatcaaa aacaagacga ctaagataac
    52681 cccataaaaa ggaagaagcg gtttcagcat tgcctctgct tttacgcctc ctacacttgc
    52741 accgacatat agtcctgtac ctactggcgg cgtgatggag cctacacaca gattcatgat
    52801 tgaaaacaac ccgtaatgta caggatcaac ccctacactt gtgacgattg gtaaaaatat
    52861 tggtgtaaaa atcaagatag caggcgccac atccataaac atacccacca gtaataacac
    52921 aagattgact aataacagaa taataaattt attatccgtt acgcccataa tcaacgaact
    52981 aattgcctga ggaataccgg taaacgccat ggcgaaagac atcatggaag aagtagccaa
    53041 taagaacatg atcgtccctg acattgctac tgattgaaac aacatattag gtatatcttt
    53101 tagttttacc gttttatagt aaaacatagc aatcaacagg gagtaaatga cagctatcgc
    53161 tgaagcttct actgctgtaa atatccccgt caagatacca ccgataatga tgacaatcaa
    53221 tagaaggcta ggaatcgcct cttttattat ttttccagca tgagccatct gtcctttttc
    53281 gacaacaggg tatttattct ttttagcaac gatgaatgct actagcatga ttcctagcgc
    53341 ccacaaagcg cctacgagat aacctcccat aaacaaagca gagatcgaag caccaccagc
    53401 aacaagtgaa tacatgataa aagcagtact tggaggaatg accatacctg tcggagctga
    53461 cgcgatattg accgctgtcg caaacttccg gtcatatcct tcttccactt gctgagggat
    53521 caacactccg ccaatcgcgg tagaagcggc aatggccgag ctagagatgg aaccaaataa
    53581 agcattccct aacacattcg tatgagccaa agcccccggc acgcgcccga cgaacaacat
    53641 cgcaaaatcc actagtttct tagctatccc tccattattc atgataatgc ccgagagaac
    53701 gaaaaacgga atagcgatca gcgaaaaact attgatactt cccaccattt tttgagctga
    53761 actaaaagca gaaacatcaa acggtataac taacaataaa gtcatcatcg atgagaatgc
    53821 aatacttata gcaatcggca tccctaatac aagcaacaca acaaatacaa aaaataacac
    53881 taatccggct tctattgcca ttttattcct ccatttttat attttttctt gaattgctgg
    53941 cttgttgctt aatgtatcga ttagattgat caggctatag ataatgatga gtacccccga
    54001 tacaggtact gacagataaa catatcccat aggaatactt aaagaaggcg agatctgccc
    54061 cattgtcaat gtgacagcat tccatccgcc atacaccatg atcatcgcag caaataccag
    54121 aaataaactt tgaacaacaa cttctaaaat tttacttttt ttgccagtta atttttcact
    54181 taaaaccgtt acggctaaat gtgctttttg tcccacaaca tacgcggaag acaacatggc
    54241 aaaccagaca agaccgaatc gaacaagctc ttccgtgacc gtatttggat ttcctaaaac
    54301 cgttctggaa aatacttgcc ataaaacaac agcgaccatc ccaacaagca aaacagctcc
    54361 caggatctct aataccttgt ttaaaatcat tttcatcaca gctacgctcc ttgctcttgg
    54421 atcttttgat aaaggtcttt gtaggtagga tcgtttttga atatatcatg aagtggggca
    54481 actgcctctc gaaacggtgt attatctaca tcattgaatt ggactccatg ttcttcttgt
    54541 gctaaagctt tttcttcttc aattgctttt gcaaaagctt caatttcaaa aaccgttgat
    54601 tctttcgctg cttcttcaat ggctttttcc tgctcatcag ttagctgttc tttgatggca
    54661 tcattcatga tgatgatatc tggcacacgt gtatgctcat cataggaata gtatttagcc
    54721 acaccaccat gtccagctgt atacaagaca aattcattgt tttctgatcc gttgatcaaa
    54781 ttggattgaa gagacgtgta cacttcatca cttcccatag gtacgggcga accgcctaaa
    54841 agctctacca ttttgatagc ggtttcgctt tgcatcacac ggatcttctt tcccttcaaa
    54901 tcttccggcg tatggatcgg accgtctacc atataaaagc tgcgctgacc agaatcataa
    54961 taggtcaatc cggtaaatcc taaatttttg gtcgattggt agattggctc cattatttct
    55021 tcattatcca tcaccttaaa gaaatgttct tcatcattga atagataagg aactgaaaaa
    55081 atcgaataat ctttagagaa actttccaac gctgaggcac ttacttttgt gaaatctact
    55141 gctcctgact gtgtcaattc gatcagttca cgttctccac ccagttgtcc atctgggaaa
    55201 tactggatct gtacggaacc atctgttttt tcttttacta aacgcccaaa ttcattcatt
    55261 gcatcaatta ctggctggct gttgcttgca taagcaaagc gcaaggtaac tatctcattt
    55321 acatctgcat ctgcgacagt tgccacacta gaattatttc cgcagccgct tagacctagc
    55381 agacctaggc taagcgaact tgctgcaaac agcagtgatg tttttttcat atgggtttcc
    55441 tttcttttaa caataagaga cgagcaattc tgtcaaacaa agcaccgtta acgactgtcc
    55501 ataaggcatt gctgtgattc cgatattccg ataaaaatct aaactgtccc ccattcctgt
    55561 cccgattgaa acgttttgaa cttctccttt ttcatcgatt tgttcaagca atccttggat
    55621 agcacgataa gcgacttctt tatattcttg tggtaaataa cgtttatgga ccgctttcaa
    55681 aataccgtaa gcaaatcctg cagttgcaga agattctacg taagaagaag gatcatccaa
    55741 caacgtatgc cataaaccgc tttcagactg ataagttttt aatgcacgca cttgtgcttc
    55801 aagtgtttcg atcaataatt tgcgcaatgc atcttctttc gataattcta agatttcaat
    55861 gatctctgga atagcaatcg tcaaccagca gtttccacga gcccaaaatg cttcggcata
    55921 gttatgattt ccttcaaacg tccagccgtg ataccacaat cctgttcgtt tatccatcaa
    55981 gtatttgata tggatcataa actggtaacg agcttcttct aaatattctg ggcgattcaa
    56041 cagtttcccg atttttgcca aaggaagcac tgtcatcatc aatgtatcgt cccacaactg
    56101 attcttattt tccggtccat atgtggcatg ctgtaacccg tcttcatttg tccgaggcat
    56161 gtcattcatg acccattctg cccattgttc taaataaggc aaatagcgtg aatctttcgt
    56221 gtcttcatac aagtaagcca tagtcaatag cggtgccatt gtattgacgt ttttgggcgg
    56281 agcgccttct tccatacgat cctcaaacca ttcattgacc acttgataag cgcgaggatt
    56341 ttttgtcatc tggtaatttt tataaatacc atatagaccg acaccttgtg gccaattcca
    56401 cactgtccag cttttgtcat ctactttcag tccatcaaag tccaacaaaa attcaccatt
    56461 atcgtctttg atcgttgtca ggttttcaac gagcaggtca attttttctt tcactaattc
    56521 tttaggtaca aaaatctctt ctttaataat catctttacg ccaccttttt aaacgctttc
    56581 attttatatc cttaatatag cagtaatacc gtccactata aatatcgctt tttgaacaaa
    56641 aactgtctaa aattgaccta aatgttaaat aacaaaagta actttcagtt acttggaaat
    56701 taaaaaaaga acttggcgaa acaacgtttt ccaagttctt tttcatctat tttcttatct
    56761 tttttctacg ctttcttttg cttatccgtt gtaagcatca atgatgatct gtttcaattc
    56821 agagatcaat ggttctttcg gattagctgt cgtacattgg tcttcgtaag ctaattcagc
    56881 catacggtct acggttgtat ctagtgtttc ttgtgtgact ccttgagctt ttagactcat
    56941 gttgatgccg acagattttc ctaattcata aacagccgtt gctaaagctt cgactaattc
    57001 ctctgttgtt tcgcctttca gacctaagaa ttttgcgata tctgcgtaat ctgtatctgc
    57061 acggaaatag tcatatttag ggaacatcgc atgtttttgt ggatcttttg cattatagcg
    57121 gataatatgc ggtaaaagaa tcgcatttgt ccgtccatga gggatcccgt attccccgcc
    57181 gattttatgt gcgactgagt gacaaatacc taggaatgcg ttagcaaacg ccataccagc
    57241 cattgtagaa gcgttgtgca ttttttcacg tgattccata tcaggtgttt ttactgattt
    57301 ttctaaatag tcaaagacta acttgattgc ttgtaggctc aatccacgtg tataatctga
    57361 agccatgact gaaacatagg attcgattgc atgtgttaac acatccatcc cggtatctgc
    57421 tgtgacagat gctggaactg acatgacgaa ttgaggatcg acgattgcga catctggcgt
    57481 caatgcataa tctgctaacg gatatttcac atgtgtttca ctgtcagtga tgaccgcaaa
    57541 tggcgttact tcagaaccag tccctgatgt tgtcgggata catacgaatt gtgttttttc
    57601 tggtttgtcg atcttatatg tccgtttacg gatatccaag aatttttgtt ttgcaccaaa
    57661 gaaagatgtg tctgggtgtt catagaacat ccacattccc ttagctgcgt ccattgcaga
    57721 accgcctcca agagcgatta ctgtatctgg cttgaagtct gccatcagtt tcgttcctgc
    57781 gtatacggta tttgtcgatg ggttcggttc aacatctgag aagacttcga tcttcacatc
    57841 atttttacgt cgtgccaata cttcacgaac tgtatcgcag taaccgaatt ggaccatacc
    57901 agggtcacaa acgatcatga cacgttcaac gttttccatt ttctctaagt acaatagaga
    57961 gttcttttca aagaagattt ttggcggtaa tttgaaccat tgcatgttat ttctccgttt
    58021 cgctacagtt ttgacattga ttaagtttac agcagagacg ttacgagaaa cagagttctt
    58081 accataagaa ccgcatccca aagtcaatga cggaatcatt tcgttataga tatcaccgat
    58141 gccgccttct gcagatggtg tattcactaa aatacgacaa gctttcattc gaagaccgaa
    58201 tttgacatgc aactcttcgt tttctgaatg gataactgct gtatgtccta atcctccaag
    58261 attcaacata ccttcacaca aatcaaacgc atggtccgtg ttgttagctt tgatcatggc
    58321 aagaactgga gaaagttttt ctcttgatag cggataatct gggcctacgc cttccaattc
    58381 agcaatcagc attttcgttc cttttggtac actgattcct gccaattttg cgatttccat
    58441 cgcagaatgt ccaacgattg atggattgac cgcatatttt ccttcgttca tcactgcatc
    58501 ttctaatttt tgcaattcat ctggttttac gatataaact tggtgtgctt ggaattctgc
    58561 ttttactgct gcatagattt ctttatccac gatcacagct tgttcagaag cacaaatcat
    58621 tccattatca aatgttttcg aaacgatcaa atcgttcact gcacgtttaa tttttgctgt
    58681 tttttcaata taagctggta cgttacctgg acctacacct aaagctggtt ttcctgtaga
    58741 gtaagcagac ttgaccattc cagctccacc tgtcgctaag acgatcgcga tacctggatg
    58801 gttcattagc atagaagtcg cttcgatcga aggatgttcg atccattgga tacaattttc
    58861 aggagctccg gcagcgatag cagcatcacg taccactcgt gctgcttctg cagaagattt
    58921 ttgggcactt ggatggaaag caaaaacgat tggatttctt gttttcaacg cgatcattga
    58981 tttgaaaatc gttgtggaag tcggattcgt tgttggagtt actccgcaaa ccacaccgac
    59041 tggttcagca atttcaatca accctttttg gacatcttca ttgatcacac caactgtttt
    59101 atcatgtttg atattatgcc aaatatattc ggacgcatac atatttttga ttgctttatc
    59161 ttcgtaaaca ccgcggcctg tttcctctac agccatcttc gctaatggca tatgttgatc
    59221 caaagctgcc attgccattt catgcacgat atggtctact ttttcttgat caaagctttc
    59281 catttctttc aatgctgcat ttgctttttc tgccaaatca tcaatcattg cttgtacgtc
    59341 aattgtcttc gttttttctt tttctattac tttagccatc attatcctcc taatgggtca
    59401 tggttatttg ttaaataatt cacatgtata tcatacaata tttatttttc tatgtaaaca
    59461 cttttttgtg atttttttca cagttatttt taaatataaa attgctttat ttacaggtgt
    59521 ttgtatagaa aaatatataa agttatttat tattatttat atgacacacc cgattattca
    59581 atattgagca atatatccca tgctcttatc tctttctttt ttgaataaaa aatgaggtag
    59641 gacatctttc tgccctacct cgtctttaaa taagctttga tacttatttt tcttccttct
    59701 cttctgtctc ttccagcgtt tctgttgttt cagtttttac ttcaactgtc tcagctggtt
    59761 cttctgttgt ttcaacagta gtcgttgcat catttgttac gacagtccct ggtttgaccg
    59821 ttttgattgc tgcacgatcg tactcaagga agatcccttc gcagtctaaa acaactgtcc
    59881 gtttgtcatt gtcgatttct gaaacaactc catgtaatcc gccgatcgtt acgactgaat
    59941 cacctggttt catgctatct aacaagtttt gacgttcttg ctgttgtttc ttttgcgaac
    60001 gtgacataaa aaaccacatt gctaatagcg cgataaacat cacaagcatt ggtaatgttc
    60061 ccattttttt cacctcacta attctgtatc tacaaaaaac actttagcag aaaaatgctg
    60121 ataacactag ttttttactt aatttttaaa agattttcct ttagaagctt tttgcgtttt
    60181 ctttattgaa cccgtattct tcaaaaaagg cttctctaaa ttcaagcaaa ttatcatcca
    60241 tgattgcttg acgtacttgt ttcattagat tcaacaagaa gtataaattg tggtaagaag
    60301 tcaaacgaat cccaaatgtt tcatcacatt tgatcaaatg gcggatatag gcacgtgtat
    60361 agtttttaca tgtataacaa tcacatttct catcaattgg acggaaatca tgggcatatt
    60421 tcgcattttt cactactaga cggccttgag aagtcataca tgtgccattt cgagcgattc
    60481 gagtaggcaa gacacagtca aacatgtcta ctccacggat aacaccatcg atcaatgaat
    60541 cagcagcacc gacacccatc aagtaacgtg gtttgttttc ggggatcaac ggtgtagtga
    60601 attctaatac acgattcatt tctgatttag gttccccgac agataacccg ccgattgagt
    60661 aaccagggaa atccatcccg actagatctt tcgcgctttg acgacgaaga tcttcaaacc
    60721 ctgctccttg gatgattcca aataatcctt gacggtctgg attagcatga gctttcaatc
    60781 ctcgttctgc ccatcgagac gtacgttcta ctgatttttt cacgtagtcg taactttcat
    60841 cgaatggtgg acattcgtca aaactcatca tgatatcaga gcccaattta ttttggatgt
    60901 tgattgcttt ttctggtgat aaaaacatac gcgaaccgtt caagtgattt ttgaaatgca
    60961 cgccttcttc ttcgatattc cgcatatcac ttaatgaaaa aacttgaaag ccgcctgaat
    61021 ctgttaaaat cggttgatcc cagttcataa atttatgcag tccgccagct tcttctacta
    61081 agtcttcacc agggcgtagc cataaatgat atgtattact taaaataacg ccagcaccca
    61141 tttctttcaa ctcttctggg gacattgttt ttactgtagc taatgttcct actggcatga
    61201 acattggtgt ggggaaagtt ccgtgtggcg tgatcaattc ccctaaacgc gcgccagtat
    61261 gtttttcttt cttgattaaa cgatagcgaa tggcaggttg cgtcattcat ttccctactt
    61321 tctatataaa atatcttgac aactcccacc atcataatcg tttcaagtgc tttttgcaag
    61381 ttccctcggc ttccttctac tttatttaat attctttttt ttatcctttt tttatgaata
    61441 acaaaaaaaa gaaaaacatt atgacagaaa tattttttga tacatggtat attggtgtta
    61501 ttaaagaaaa ggagggaaaa atcatgcaat cttctgcaga attaaaacgc caagcaaaag
    61561 agagtctaaa aggacgttgg ggacaagctg ttttactaaa tctaatccct acattgattg
    61621 gtattgctac tattcttctt attatgattc ctattatctt gtttgccacc accatatatg
    61681 atggatcagc gagcgtctca gaagcgacaa cttcaggagg cggtagttca ggaggcggtg
    61741 gcggaattat ttccagcatc attagcgctt tgttcatgag cggtatttct tggacttatc
    61801 ttgatatttt acgtggacaa aaagatcaga tcgaaccatt caaagatgca tttcgtggat
    61861 tcaaaggttt gtttatcggc ggagtgatca gcttagctgt gctgatctcg atctttacaa
    61921 cattatgggg tttgctatta gttattcctg gaatcattaa aagctattct tattctcaaa
    61981 gctattttat ttactacgat atcgtccaag aaacaggaca aacacctaaa gtactggata
    62041 cgatcactgc aagtcgaaaa ttgatggatg gttataaagg acaacttttc tggttagatc
    62101 tttcatttat cggctggcat atcttagcat tagcaactgc tggtattggt tatctatggc
    62161 tcagcccata catttctgca acaaaagcag cattttatga acaattgcca aaagatattt
    62221 aaaagagagt gtgacttgtg accgaggggg tggcaggaga acaccgttta tcgagaggca
    62281 gtaaaagaaa cattcagccc attagcaaaa aggaggtgtg acaacattca tgtcacacct
    62341 cctttttgta tagttccagt aaaaagaaaa tcaacttaga aacagttaat cattcctctt
    62401 cttctgcttc cggtaatcga tggaacttga tcagttcatt caccgcgatt ggtacgatag
    62461 ataaaatccc taccaagaac cagtgattca aactgatgtg tactaggccg aatagttctt
    62521 gcgtaaatgg cagcaaagca acagccgttg taatagctaa tgccagtaac gccatttcta
    62581 ccaaagcttt attggtcgct aaattgactt tgaagatcga ttggctgctg cgtacattga
    62641 acacatgcag aatcgatgaa taagctaaga tcaagaatgc aacagtttga ccgacatgct
    62701 gacttgcgtc tacccatggg ctgatagtat cgacataact acctaaataa taaccaaaca
    62761 aggttacgat ggtgaagacc cctgcattta tggcaatttt ttgcaataaa cctcgagcaa
    62821 agatcccttc atttttcgga atgggtggct gatccatgat gccgtgttcc gctggctctc
    62881 ttcctaaagc aaatcctgga agtccatcag caactacatt gacaaacagt agttgcacag
    62941 ctgtaaatgg tgctccccat cctaacagca tcgcaatcaa aacaataaag atctccgaaa
    63001 tattacagct tagcaaaaag ttgatagctt tacgaatatt ctgataaacc gaacgtcctt
    63061 gactgacagc gtctacgatc gtcgcaaagt tgtcatccgt caaaatcata tctgcggcac
    63121 tttgcgccac atctgttcct gtgatcccca tggcacaccc aacgttactt gctttcaacg
    63181 ctggtgcatc attcacacca tccccagtca tcgctacgac tgcacccgta cgttgccaag
    63241 atttgacgat ccggatcttg tcttctggcg ttacccgagc atagacagag agagctttga
    63301 cacgcgcatc taattcttcg tctgataatt gatgcagttc tgatcctgaa agtgcttctg
    63361 acggatcatt caagatacct aattctttcg ctatggcact ggcagtcacc acatgatctc
    63421 cagtgatcat gactgttttg atgccagcct ttttcgctcg cttgattgct cctttacttt
    63481 ctggacgtgg tggatcgatc attccgatca gaccaatcaa acgtaagtct ttttccagtg
    63541 cttcagaaga aatatcttgc ggttcttcgt cataagtagc ataaccaaca gcaatcactc
    63601 tcagtgcccg tttaccaaag cgatcattaa cgatcgccgc ttgttctaca tcgcctgaac
    63661 taaagcgcgg agcaagaaca tcgaatgctc ctttggtgat tgagatgtat ttttcgccca
    63721 tttggtgaac tgttgtcatc atttttcgtt cagaatcaaa aggaagctcg tttactcgtg
    63781 gatatttttc ttctaattct gcctttgtat gataattctc ttcaacagcc cttacgatgg
    63841 ctacttctgt tggattacct ttgataacaa ggtcgtcatc ttcttgctcg accgtcacat
    63901 ctgtacatag tgcagccatt ttcaatattt ccatcgcgct gttcgtcatt gaatcttcga
    63961 tattcgttac ttcatcttct ttgctccata cccggcggac gcgcatttca ttttgtgtca
    64021 gcgttcctgt tttgtctgag cagataacat tagcggttcc tagcgtttca actgctggca
    64081 actgtcggat gatcgcatgt ttcctcgcca tcttctgcac accgtatgca agtgtcaacg
    64141 taacaataac agtcaaggtt tccggtacag ctgcaacagc caaggaaatc gaagtcatga
    64201 acatctcaag gagtggttct ccttgcagtt caccaatcac aaatactaaa gccgcagccg
    64261 ctaaagcgat catactgatt cgtttgccta gctgattcaa tcggacctgt aaaggtgttt
    64321 tttgcatagt attttcgttc aaaagatccg cgatcttacc catttctgta gccatgccaa
    64381 tggcagtgac gatcgctttc ccacgacctg cagcaaccgt acatccttta aataccatat
    64441 taagttggtc acctaatgac tcatcttctt cagcaataaa tgctgcatct ttttcaactg
    64501 cttcactttc tccagtcaac gccgattctt ctacacgtaa ttgtgatgct tcgatcaaac
    64561 gggcatcggc agaaatagca tcaccggact ctaaaacaag aatatcaccc actaccagtt
    64621 gctctgactc aacagtggtc actttgccgt ctcgtatgac agttgccgtt tgtttattca
    64681 tatcttgcaa ggattccagt gctttttctg cgtttccttc ttggacaatc gccaataccg
    64741 agttgatcac aacgatagcg atgatcagca gtccttcaaa taaatcccca tgttctgtag
    64801 caaatgcggt ataaaaggaa atcaccgctg ctacaagaag gatgatcgtt gtaaaatcgg
    64861 acaagcttcg aaagaatttt ttgatcatcg attctttcgg cgcctcatcg aatttattca
    64921 atccctgctt ttttcgccgt tcatccactt cttgtgaaga caacccagta tctggatctg
    64981 cttctgttac cttctttact tcttctattg tctgcttgta ttcttccatc ctattcctcc
    65041 tttaaaatct tcgtacaaaa aaaggtactt attttactat aacatccttt ttttatttac
    65101 ttcaaataaa gggcttatcg attatttgtt aagaaagcgt aaaatttaaa gtgcttatat
    65161 ttgcaaacgc taccaaagga tgctattata tagatgtaag gaaggaggat accatcaaat
    65221 agacagaaga atttctcgat agaacagtgt aagcaaacaa agttgttaga agtacaggtt
    65281 tcacccagac atgcgtgtag agtacaaacc tataaatagt gaatgcgtat ggatgtttgg
    65341 atcacgaagt atccgaaaca agaagtaatg cgatacgtaa caattgaata acgtaaacgt
    65401 ctgaaaattg aataggaaca agagatgttt caaatgttga agatgtaacg aaaacaaaat
    65461 ttttgtttaa catgaagaaa ttcaacaccg tgctttgcat gtatgatgga aagttacaat
    65521 catttctgtt tatttgaatc cttccgaggt acaagaaagc cgagcttatc gagagctcgg
    65581 ctttttcttt gtcataaaat ctttgtaaag cttttttgtt attcaaaact agcggctttt
    65641 cataacctta tttcacgaac atcgcatctc caaaactaaa gaaacgatag cgctcttcaa
    65701 tcgcatgctg gtaagcagat aaagtcaatt ctcttcctgc aaaggcacta actaacatga
    65761 ctaaagtcga ttttggcaaa tggaaattag ttgagaaagc ttctaccact ttgaattcat
    65821 agccaggcgt aatgaaaata tcagtccatc cgctgtctgc tttgatttct ccattaaatt
    65881 tcgttccaat cgtttctaat gttcgaattg aagttgttcc gacagccacg attttcccgc
    65941 catttttacg tacttggttc aatcgctcag ccgcttcttc cgtcaaacgg tagaattcac
    66001 tatgcatatg gtgttcttca attttatcta cgctgacagg tcggaatgta cctaacccta
    66061 catgtagtgt cagatagact aattcaacac cctttgcttc gatctcatca agtaattctt
    66121 tcgtaaaatg caatccagct gttggcgctg cagcagaacc attttctttc gcatagacag
    66181 tttgatagcg atctgggtct tccagacgtt ctttgatata tggaggcaat ggcatttctc
    66241 ccaatgattc aagaatctct agaaaaattc cttcatactc aaagtcaatg atccgtccgc
    66301 cgtgttccaa ttcttctttc actactgctt gcaatctgcc atcaccaaaa gagattcttg
    66361 tcccaacttt ggcacgtttc gcaggtttga tcaatgtctc ccacgtatct ccttgtgtat
    66421 tcgttagaag aaggacttct aaatgcgcac cagtatctgg tttttctcca tataaacgag
    66481 caggcagaac tcgtgtatta ttcataacta gcgcatcacc aggctgtaac tcttcaatga
    66541 tttcatggaa atgtttatct tccatctctc cagttttccg atccaaaaca agtaaacgag
    66601 aatgatcgcg gtcttttaat ggtgtttgtg cgattaattc ttccggcaag tcaaaatcaa
    66661 aatcttctgt tgttaacata tcgtcactca ctttctatca tgtgcttcat cattctatca
    66721 tgtttttcgt tctgttggca aaatcagcac tttttcactt ctattttttg ttttcctaaa
    66781 taaaaaaact accctatttg tattttttca ttgttttagg catactagta atagatagtt
    66841 cttcattgaa aatagaaaaa gaggtggcac catgattgaa tttcaaaatg tgtcaaaaat
    66901 ttataaaggt ggaaaagtcg ctgtagagga cgtcaatctt tcatttgaaa agggtgagtt
    66961 catttgtttt atcggtacga gcggaagcgg aaaaacgacg acgatgcgga tgatcaaccg
    67021 aatgactgat ccaacacaag ggaaaatttt gattgatgga aaatccatcc aagaaattga
    67081 tccagtggaa ttgcgacgtc agatcggcta tgttatccaa agtattggat tgatgcctca
    67141 catgacgatc cgtgaaaata tcactcttgt ccaaaaattg ttgaaagtca gtcaagaaga
    67201 acggaataaa acagctgaaa aaatgattga tcttgtggaa ttgccccgtg agatgttaga
    67261 tcgctaccca catgaattat ctggtggtca gcagcagcgt attggagtcg ttcgtgccct
    67321 tgcagcgaat caagatatca tcttgatgga cgagccattc ggtgcgcttg atccaatcac
    67381 tcgtgattcc ttgcaagacc ttgtcaaaga tttacaagag cgtttgggaa aaacgatcgt
    67441 atttgtaacc catgacatgg atgaagcgat taaactagca agccgtatcg ccatcatgag
    67501 tgaaggccgt gtgatccaat ttgatacacc agaaaatatt ttacgtcatc ctgcaaacga
    67561 tttcgtagaa gagttgattg gagaagatcg cctactacaa gccaagccaa atgcgacaag
    67621 agtcggcgaa gttatgctaa atacagcaat cacgattaca ccggaaaaat cattacaaga
    67681 agcaatcaaa ctgatgaggg aaaaacgtgt agatacgttg ttagttaccg ataattcgaa
    67741 tgtattaaaa ggatttatcg atgtagaaac gttgaataaa aaacgaggaa aagtatccag
    67801 tgtcggcgac attttgaata aacatgtttt ttacgtaaaa gaatccgcct atcttcgtga
    67861 taccttgcaa cgcattttaa aacgcgggct gaaatacgtg ccggtcgttg atgaacagaa
    67921 caaagtcgta ggtatcctga ctcgtgcatc attagtggat atcgtctacg atgtgatttg
    67981 gggagaagat cccgcaacta ctgatgttgc agagtcagct actcctgaag aatctaagga
    68041 ggtctgacct atgcagcagt tttttcatca gcacggttca gaaattctct caaaaggttt
    68101 tgaacatctt tatatttcag gacttgcttt gatcattggt atcatcattg ctgtaccgct
    68161 tggtgtctta ctgacacgtt ttccaaaagc tgccacgatt gtgattggct taaccagtgc
    68221 cttgcagaca atcccttctc ttgctttatt ggcattgatg atcccgctat ttggcgtagg
    68281 taaattacct gcgattatcg cactctttat ttattcatta ttgccgattt tacgtaatac
    68341 gtacattggg atgaaaaatg tcgattggaa ttatcgggat gtggcaaaag gcatggggat
    68401 gactgagttc caatccattt tttccgttga attgcccatt gctatgccaa cgatcatggc
    68461 tggtattcgt ttagctgccg tttacgtgat tgcatgggct acacttgcct cttatatcgg
    68521 cgctggtggt ttaggcgatt tgatttttag tggactgaat aattaccaac cagatctcat
    68581 tttggcaggt acgatccctg taacaatttt agcactattg gctgattggc ttctaggtct
    68641 cttggaacac cggctgacac cgatcgcact tagagaggag aatgaagaat gaaacgtata
    68701 ctaaaaatga ccatggttct tttctctctt cttatacttg cgagttgttc cttccctggt
    68761 cttgccagca atacagatga agacaccatt tcgatcacag gtggaatcac ttcagaagca
    68821 cagatcttag caagtctagt tgccggaatg gttgaacatt atacagataa aaataccgca
    68881 atcatcaaca atctggctac tacaactatc aaccatcaag cgatgatgaa cggagatgct
    68941 tcaatttcag cggctcgcta cacaggaaca gatttaacga ctacattgaa ccttcctcct
    69001 gaaaaagatc cgaaaaaagc gtttgctacc gtgaaagatg aatttgagaa aagatacggt
    69061 caaacgtggt tcccgtccta tagttttgaa aatacgtatg tctttcttgt tcgaaaagac
    69121 accgcacaaa aataccatct atctaaagtc agcgatctga aaaatgtagc ggatgaatta
    69181 gtagctggtg tagatacttc ttggatcaat cgtaaaggag acggttatga cggcttccaa
    69241 gaaacttatg gcttctcctt caattcgata ttacctatgc agattggact tgtttatgac
    69301 gcagtcgaag caggaaaaat ggatattgtt cttggctact ctacggatgg acggatcgcc
    69361 agttatgatc tagtcatgtt ggaagatgat cgtcaattct tcccaccata tgatgctgct
    69421 ccagttgtag acaacaagat attagctgat acgcctcatt taaaagaagc cttaaataag
    69481 ttaggtcata ccatcagtac ggaaaaaatg caggaattga actacgaagc agataataat
    69541 ctagtggaac catcagtagt agcacaacgt ttcttacaag aaaaccacta ttttgaaggg
    69601 aagtgaagca attggataaa atgaatgtct ttcaacaatt tttctattat ttccaggaaa
    69661 atggctccta tatctttgca caatttatcc gtcacttcct gatttctatc tatggtgtcc
    69721 tctttgcagc agttgtcggg attccggttg ggatcatgat ttctaggaga cgtaaattag
    69781 caaactgggt gattcgtttg gcgaatatca tccagacgat cccttctcta gccatgatct
    69841 ccattttaat cattggatta ggcctgggag tcaatgtcgt gattgttact gtatttttgt
    69901 attccctctt accgatcatc aagaatacgt ataccgggat gatccaagta gacaaaaaca
    69961 tccttgatgt cggcaaaggc atggggatga ctgctagaca acgactattc atggtagagt
    70021 taccactctc tgtttctgtt atcatggcag gcataagaaa cgcgttagtt gttgccatcg
    70081 ggataaccgc gatcggtgca ttcgtcggtg ctggtggtct tggagatatc attatccgag
    70141 gaaccaatgc aacagagggc acatcgatta ttttagcagg tgcattgcca actgcattaa
    70201 tggcgatcat cacggactgg cttttaggta ttttggaaag acggctagat ccagccagcc
    70261 gtacatcacg ctgatgttat tgtaaaaaac aaaagcttct gcgaccattt gttggtcgca
    70321 aaggcttttt tagttctgtc atttttaagg caataatcca ctctgattct tccctcctta
    70381 tgggcaaaga gttgcttttc ttagctattt atccattccg tatactccaa cttcatactg
    70441 ccaacgggtt catatctgca tccaccgact aagttttttt cttatccgct aaggcatttt
    70501 gccaatccat tttcccatca ctcgtcatgg aattcatacc acatgatctc taaatactcg
    70561 tctgcttgtt ctttgaattg ggcatcaatt cttacatcct ttggcgtggc tttcatttaa
    70621 gccttttcca tcagtcctcg attgttcgat gccttcagct gcatcatcaa aactggtgac
    70681 tgccgtatcg gtaacttcga tcatctttta tacaatcggg aacttgccat cctcatcctt
    70741 ggctaaaaac atatctagcc attccagctt ctcgccatgg gaggtttgcg gttcctaaaa
    70801 ccggtacacg attcttatgg actgcatccg tcgcaactag acttggcgat acgatgatcc
    70861 ttcaccagaa gagcaccccc gtaaaccaat tgatcgatat attgccaata agaaaagaca
    70921 ttggcgtaaa agatatcgat ccctcgtgat gcattgccgt tgatactgct attcatggcc
    70981 gaaagcgcca cgactttaac ttcttccgtt tgagtgacat tcatgttcgg caatgtcgct
    71041 ttggataccc gctctgctaa aggaacgaca ctggtattgt atttcgtatc tgtatctttt
    71101 ccaaaagacc atgccaacga atcctctggg aaccaataag acgactccgg ttgattgtcc
    71161 attgcttttt tcaacatact tttggctgtt tctcgataaa cgacatttcc aattgtcttc
    71221 gcctcacttt ggcgataatc gatggtcgtt gccactgcca acactaacaa cgatgctcca
    71281 attttactga ttttccttgt cacacttctt cctccttgtt ttacataaac ccgtcaacat
    71341 tccattccta aactcaaaca atgacccttc aaaggtggag atataggaac aaattaaaga
    71401 aatcatgcaa taaatccaag aaggttggtt ttagaacaaa aaaagagtct cctttttggg
    71461 gagactcttt gttaactatc taaaaaggtt ggctcttctc acttcactca taatgtgtcc
    71521 aggcagaata aatttctaca actttatttt cctcatcaac tttgtaaacc actcgatgct
    71581 gtctattcag cctgcgtgag tatctgcctt catgtgtagg tctcagcttt tcaaaagact
    71641 gcgtgggcat atatggatct tccttcaatg tctgaatcac ttcttcaaat tgtttcttta
    71701 aattcgtttg cttgattttt cttaaatcca ctttcgcaga gtttttgatt gcgactgtat
    71761 agttactcat caaagagctt cccaatcaat atcatcgata ttcgtaaagc tactgtcgtc
    71821 tttttcgcgg tctcgtactt tatctaaagt acctgtttgc tcaagaaaaa gggtttcttg
    71881 aatcgctctc cagtcttcca gcccaatcaa tacagcattg tttccactac gatcactaat
    71941 aatctcgatt tcagtatgat tttcatttac ctctttcaat aactgataaa aatttttacg
    72001 agcagtgcta ggattcatcg ttgtattagc cattgtctct cctccttttt ctgatataat
    72061 tatagcgtac ttgattaagt acgtcaaaaa aatacaataa agcacttaaa ttcagcaaac
    72121 ttttcctctt ttttacatag agaaaaagac ccctttttag ggaggatctt tgtccacgct
    72181 cacttcttac tcctttacga ctagcggtag ccaaacgtaa agtaattggt aacaacgtat
    72241 catctttagc aaaggtcgaa tccaaagcct gtgagtctat gcaacaacac caatacacga
    72301 aggttcctcg ttgcagtgtg acttgattga tatcttgaat aacctgagga tacgcacgaa
    72361 agatttgtaa cggttattca aaactgattt tggccgtcaa gtcttctact gcctcaaaaa
    72421 tgattgcctc tttcgtctcc tgtcattcat gttcactatc gatttgatac ttgcttagac
    72481 cgttgggttt gtgaatcacc aattaaaaat ggcactgagt tatggtaaca aaaaatggtc
    72541 acttgacgag gctgagattc ctacttatga agacacatgg cacttaagag tcgaggtaaa
    72601 ggaagaagct gaaaatatag gaggctgtac attatttggc aaaggattcg gaaattatga
    72661 tcaagacatc aaaatcaaaa tgttttacag ctaaatagga agaataataa catttcatac
    72721 gctgttccca tctttaatgg cttatagagg gcacctttag ctgagaataa gacaaaacag
    72781 accctctagc ttcaattaag agctagaggg tctgtttttg attttaaaac ttggtttatt
    72841 tcttcaaatg gtagctatag gtgctgacaa cgatattttc acgccaagac aatcgcaatc
    72901 ttaaccgcaa acttgtttgg ttatggagaa tattctgcca gcgtctgttt ggtacaaatt
    72961 gaggaatcaa cacagtagtt gtatagtttt gtttcgctgc atttttactt acgatatcta
    73021 cataacggat aattggattt tcaatcgagc gataagaaga gtggacgatt gaaaaacgga
    73081 catctgggaa atgcttttta aattctgctt cgatttcttt ttctttttcg acatcttcgt
    73141 ctagcgaaac atgcatcgca acgacataat caccgatcga acgtgcgtaa ttcaacgcac
    73201 cgatatttac ccgtgtcaca ttcccgacta atacaagaac ggtattcccg tcataatcat
    73261 gtagttttgc atcattttct aaacgaagct gttctgctac ttttttataa tgatcatgga
    73321 tcttataaaa aatgaacata acgattggca taatgatgaa gaaaggccaa atgtccccta
    73381 accgatagac aaacaaaatc gcaatgattg catatgagat gaacgcaccc gtaatattgg
    73441 caatcgattt gcttaaccat ctttttcctt cttttttcca tttgacgacc atccctgttt
    73501 gagataaagc aaatggaatg aacacgccga tagagtataa cggaatcaag cgttctgttg
    73561 agccatggaa aataaacagc aatacgatcg aacctagcgc tagtgtgata atcccattgg
    73621 aatagcctag tcgatcccca cgatcttgat acatgtgagg catgaattta tcttttgcca
    73681 gattgtatgc aagaactgga aaagcagaaa aaccggtgtt agcagcaact gctaaaatca
    73741 gcgctgtagc aaattgaagg acgtaataca aaataccatg tccaaagaca gctttaccaa
    73801 tttgagacaa aacagtgact tctttttcag gaacgatccc ataccaatag ttgataaatg
    73861 tgatccccac gaagaagaaa cctaagatca atgccatcat cgtcaatgta gcagcggcat
    73921 tttttgctct tggcttctta aagaatggta cagcattact aatcgcctcc accccagtta
    73981 aagaggaaga accagaagaa aatgctcgta aaatcaaagc gatagaaaca cccggcacag
    74041 ccgctcctgg aagtgcagta gcttgcaatg gcacagcacc tgtcacgata ttatataaac
    74101 caacaacgat cagtaacgag atcacaagga taaatgtgta caccggaaat aataggaacg
    74161 atgcagattc cctcagccca cgaagattca gcatcatcag tagcaaaacg attgtcacag
    74221 aaatagcgac ttgatgaccg tagagtgctg gcaccgctga tgtgatcgct tcagcacctg
    74281 ctgagacaga tactgctact gtcaacatgt agtcgatcaa taaagagcca ccggaaatca
    74341 agccagcatt ctttccaaga ttctcactgc tgacgacata tgctcccccg ccatgaggat
    74401 aagcatggat gatttgacga tatgatagcg ttaatgaaat caataaaata ataacaaaag
    74461 cggcaatggg tagcgaatac cagatggctg cagcagacaa agcgactaaa acgacaacga
    74521 tttgttccgt accatatgca atagatgata acgcatcaga cgacaataat gccaaagcag
    74581 caaatcgggt taatttgtgc tcatcatttt cagcagattt taaaggctta cctactaaca
    74641 acctttttaa gtaatccaat ttctaaactc ctttacacac aattttactt caagttttat
    74701 agtcgaaaat ttatagtaaa caagatgtta tagtacgctc actgacctta aaagtcaata
    74761 aactttaaga aaataattgg aaaaaaacag aaaaatatca agcgcttttt caaacgcttt
    74821 aatacagcaa aaatctaaca tttttttatg ggctttttct ttgaattcta taataaaagg
    74881 atagaacttg acttagaaaa tcaagttcta tcctttttga tatcttaact tttggaagag
    74941 agatgtaagg ctgctttcta cccatcattc ttactactcg aagcatagcg cagttgtcac
    75001 aacctcttga taaacggtgt ttaaaagctt gcatctgcgg taataagccc aaccaaatta
    75061 aaaacataag aagctgtttt tatttggtcg ttcttattac ttgatgcaga gcagcttttt
    75121 tacaacctct tggtacacgg tgttcaatca gctgaccctc ggtattagct caaaaaaacg
    75181 gcaaaatatg aggaactatt tttccatttt tttctctaat actcaggtca aaacactgat
    75241 ttcacaacct ctttttttaa tgaaaaatat ggctctcatg cgccgcttct ttgaatttcg
    75301 tcattttttc ttcgatgaac ggatagattg ccgttcctac gattccaaag acaacaaaca
    75361 aaccgatcat gatccagatt gctttcgtag catttggcca ataaattcct cctgcagatt
    75421 cccgtaacaa gtttaccgca tgagtaaatg gcaagaacgg attgatcatt tggaagaatt
    75481 tccctgagac ttggatcgga tagttcccgc ctccgccaga gatcgacagt actaagatga
    75541 taatagcgat ccctttaccg acattatcga ataatgcagc caagacatag acgatcatca
    75601 tgaacgctaa ggcgatcaag acagcaaatg acacgctgta gaccggattt tggacatcta
    75661 ctcctagtaa gaaaatattc cctaatgtaa cgatcaagct ttgcgcaatc gccattgtca
    75721 aaaatgtcag catacgagca acgaattgtt ctcgtttcgt aaaattgttt cggtctttct
    75781 ttcctaaata gtattctgtc gtagcaacac ttgaaagaag aacagcgccg acccacagac
    75841 atagtgcagt ataaaacggg gtgctagctg aaccgttatt tgcgattgga taaagcgcat
    75901 tggtttgtag ctcaacaggt tgtgtaaaga agtcactttc ttttgttgcg tctagtttca
    75961 ataatttgat gacttcgcct agatcgactt cttgttcgcc ttttcggatc gcgtctgctg
    76021 ctttttggat accagctttg atatttggcc agtcattgtt gatcaagtcc gcagcagcgt
    76081 tcacagctgt ttcgacttct ggcatttttt catttactgt tgtcaatgta ccggtgattt
    76141 cattttttag tgctggccaa tcattttgga taaaatcagc ggccaatcct aatttttgct
    76201 gaatgatcgg taattcattg ttgtataggt ctgccccttc attgatgcca ttgacgatgg
    76261 tatccatatt tccattcagc attgtattgg catcatggat ttcttgtcca attgcaggca
    76321 tttctttttg atatttttct aaaattgcca ctgcattcgt tacagttgct ttcgttgagc
    76381 tgagaagcga atcaaagtcg atctggtccg ctttgctcag tgcgccttgt gcagtcccaa
    76441 tcgtatcgat gacttggtct agtagagaag tgacagtgga actgatttga cctgtattga
    76501 taccagcaat gatgccattg atattattaa caacggcatc aatttgatct agcaattcat
    76561 caatagcctt cgtgtcttca ttttgaacag ctgtgttcaa agcagatagg cggttttgca
    76621 gattgcttag caagggtttt aattgattta gctgatcaat aattggctgt aatttcgtat
    76681 ttccagcact tgtttgcaat ttagtcagga actcgaccag tttatcgatt gcattttgtt
    76741 gttgagatat tccgtcaata aagccgttca atacattgct gatgtttttc ttttcatcat
    76801 cagtcagctt accatcttca atagctgttc ttacagtatc tattaacgaa cctgtcgttg
    76861 ttgccacttg tccaattgac ttcaatgtaa catctacact gtttgtgatg cttggtatcg
    76921 catctttcag ctgagaggca cctgattttg tttggtttgc tagatcactt gcctgatttt
    76981 ctaaattttt cacatctggc aagatatctt gtacttgttg gatgatcgtc aagccttgtt
    77041 ttgcttcatc gattccttgg ttcattgtct cttggatcga agcaaaatcg ccgtcgatct
    77101 ctgctagttg cttaccggca ttttggatct ctgggatttt ttcttgcaaa tcaaggatga
    77161 tttttgcttg atctttcaac tcaggcattt tgtcattcaa tgcaacgact ttttcaccca
    77221 tctcatctac tttagggatg taatccacga attcatttgc tttattcagt ttttccttga
    77281 tttcaggtag ttgactttgt aattcgagga cttgttttgt gtagccgtcg atcgtgtcca
    77341 aattttcatc tgttgataaa atcatatctt taactttatt gatacttact aggttcgtat
    77401 cgatgtcgta acctatctca ttgaatactt tcaataaagt cgaactggct gttttgataa
    77461 attcatttgt gatttgcgat tggatcgaac ttgctccttt atcggtgatt ttcggtgcaa
    77521 tcgcattgat tttttcattt accgtatatt cgatttttgg tttcttgata tcaccactag
    77581 taaaactcag cagatcttct gagaaatcct ttggcaagta aatacctgcg taatactttc
    77641 cggaacggac tccgtcttct aattgttctt ttgaatcaac gaattgccat cctaattgtt
    77701 tatttttatg aagcgattcg atgacttgct ccccaatggc cacttcttta ccttgaaact
    77761 ctgctggctt gtctgcactg taaacagcaa ttggcagctc tccagtattt ccatatggat
    77821 cccataatgc tttgatgtta aaccacgcat atagcgaagg gatgatcatg atcgcgatga
    77881 tcagaagtgt tgcaatcggg tttttgaaaa tccgtttcca gtcaagcaaa tataatcgaa
    77941 gcgtattttt gattgactgc atagttctcc cccttcttct tttttcagct gaattacttt
    78001 accatgtatt tcatactttt ttcaatcggc ttttttcaaa aaagtcgaat ttttggacat
    78061 atcacggcaa ttgtctcatt gtaatctctt acatattgag aaataattaa ggattacagc
    78121 ctttacttta tcatgaaata aaagggaaag ataattttat gccaaagttt ttatctatta
    78181 tacgtatacg caaaaaagct aaaacatttt ttgtctttgc ccctacaaaa atgtttcagc
    78241 ttttttcgtt ttttattcct gtatttctta tttttcgaat gacaggatga ttttcccagc
    78301 aggaggatgt ccttcaacta gctgatgtgc ttggatgaca tgcttaagtg aagcagacag
    78361 attcattgaa ataaaaacat gaaaggctcc tttttggtag gctttgatta tgccagcaaa
    78421 ggcttctgca tctagatatt cctttcttgg aacaaacgat tcataaaagc cttccttttt
    78481 ttgccgcaaa tctagatctg ggaggtcatt taatgcaaca tacctgccgc ctggtttcat
    78541 gatctggatg ccggtttctc ctttgatact tcctttcgtc gcatcgatta caaggtctgc
    78601 ctgatcagca aattgcagac ctggatttgt tttatcataa gcagcaaatg ctgaagctcc
    78661 taattttttt accttttcct catttttact ggatgcactg gttaagattc ggattccctt
    78721 ttcatggaga agctggatca gacttgaccc gaccgcacct gatgctccta gtatcattac
    78781 agtatctgtc ggctggattt ccgtcaaatg gttgattaga ttataagccg taattcctgg
    78841 cgtgaccatt ccggctgctt cttcccaact cattttatct ggaatttttg ctacttttgc
    78901 tgatggcaac acgacttctt ctccgtaagt cccgccgact gcatggacag ctactcgatc
    78961 acctacatga acagttgtga catctgaacc aatctctgtc acaataccag cgccatcatt
    79021 acctggtaca taagggaatt tcaatgttcg tatctctttc atttctccta aacgcaaggc
    79081 aacatcataa ggattcacac tgaatgcttt tatttctaca cgaacatgtc cagaaccgac
    79141 ttctctggga tgagcatcga tttcttcaaa aacatcttgt gcttctccgt aaccgttaat
    79201 tgcaaatctt cgcatggtca ccatctccct ttttctttaa gtttacgttt atgcctttat
    79261 tttgacaaaa aaaatgtctt ttcgttttgg cgcatgattc aaaacaaaat agttgtcttt
    79321 tttcgcgtaa cgtgttaaat tatttatcta aaagcgtaaa gattacgatt tacgctaata
    79381 aaaaataatt ggaggaattt gttgatggct aaaaaatcaa agattgccaa agcaaaaaaa
    79441 cagcaagaaa cgattgaacg ctatgctgct ttacgccagg aattaaaagc gcaaaaagat
    79501 tacgaaggct tgcgtaaact tcctttagat gctcgtccag aacgattgaa aaatcgtgat
    79561 ttaatcgatg gacgccctcg cggatacatg cgtaaattcg ggatgtcccg tataaaattc
    79621 cgtgaattag cacataaagg tttgattcca ggagtaaaaa aagccagctg gtaatccaag
    79681 tctggctgta atgtaaagga ggagggcgca tggaccactc cttggatcat caaaaaagat
    79741 acgttcgctt cttctagcag aaatgctggt actagaagca gacgtatctt tttttacgca
    79801 cagctggtcc ttttttatat gtaaaggctg catggttact tcgctatatt tatttagtaa
    79861 caggagtcag tgcttcgata cccacactaa ttttcaatgc tcggtcaact tctgccataa
    79921 tgggtcgatc caaatggcag accttttctt tcaatcttga tttatcgatc gttctgatct
    79981 gctccaacag gataacggag tctctttcta ttcctgttcc agtagctttg atcccaatgt
    80041 gagtcggaag cttaggttta gccatttttg ccgttatggc cgcaacaatg atcgtcgggc
    80101 taaaatggtt acctagatta ttttgaataa ccaaaactgg gcgtgttccg ccttgctccg
    80161 atcccacgac tggagaaaga tcagcaaaat aaatatctcc tctttttacc ataggatcct
    80221 ccttattctt gatattctct tggtatccgc tgtcctaatc cgcaagccac ttcatagtgg
    80281 atcgtaccta attgatctgc tatatcctgc atagtgattt ctttgtctgc atttttgccg
    80341 ataagcgtca cttttgttcc gacaggaaat tcttgaggca atcggatcat cagttgatcc
    80401 atacatacac gcccaatcgt ttcacagtag ttcccttcta ccaatagaga aaaaccctgc
    80461 atctttcgtg gccagccatc tgcataaccg atcggtatcg ttccgatcca ctctgcttca
    80521 ggagtgatat atgtttctcc atagccgatt ccttcacctg ctgggagttt tttgacttga
    80581 atcaattcag aaaccagctc aagtgctggc tgcaatggat aaacttccgg tagtgcgtgc
    80641 ccagagggat taagtccgta cattgctact ccataacgaa tcatattgcc gattgtttca
    80701 tcatgccata aagccgttgc actattgctg acatgtacat atcgaggaag ttcgggaagt
    80761 tttttcagca cttctataaa gcgttctttt tgcagattcc aatatgtatc atctgcctga
    80821 tctgctgtag aaaaatgggt aaataaacct tcccattcta atacacgact ttctttgatg
    80881 aatgcagctg cctcttttac ttcttcaggt gtacaaaatc cgatacgacc catcccagtg
    80941 tctgctttta gatgaatcga aagaggcgtc tctagcttac ttttctctaa aacagcagct
    81001 gctgcttgca accattcccg tgtacctgca gttactgata aatcatgagc aacagctaca
    81061 gtcagtgcgt cgtaaggaac catattcaag ataaggatgg gctgagtaaa tccagcttct
    81121 ctcaactcga ctccttcatc taaatttgaa acacaaaagc ccgaagctcc acctgcaact
    81181 gctgcctcag ctgtttcaat agctccatga ccgtatccgt tcgcttttac tactgcaaac
    81241 aattcttttc cttgcggaag tcttgcaact tcatttgcta cattttcagt tatagctttt
    81301 ttatgtatca ctgctttcgt tgggcggtgc caagcgacaa ccatcgtttt tccttctttc
    81361 tagtcttcca aaataatttg tgcaaaagct gtttcatttg tatgagtaat actgacccat
    81421 acattgcctt catgaggtga acgcgtcaca acaggctgac cattttcatt ttttaaaatc
    81481 tcgacatctt gaaaggtaac ttttccgatc ccagttcccc aagctttaga gaaagcctct
    81541 ttgcaagcgt aacgcccgcc taaaaattct acttggcgat gaaaaggcaa ggactggaat
    81601 agtttcattt catcagaggt caagattcgt gcaatgaatt ttggtttttc ttcgatcagc
    81661 cgagtgatcc taggaagttc gactgcatcg atcccaattc cttttatcat atgcttttct
    81721 cttttcaata aatttagaac actctcattc taccaaatta taaccatttt gccacaaata
    81781 agtccacaaa taacaaaaat gaaagtttct cttaaaaaag agaaactttc attttatgtt
    81841 taatcgttat ttgaacggat tacaaatccg cgttttttat cattgtgacg tttaccgcca
    81901 tctttttggc tgttattatt tttgctataa ccgccttttg atttgtttcc acgataatta
    81961 ccgccgtcac gacgattacg gttgtttccg ccaccacgtt tgccattttt attgtatcct
    82021 tttttctgca ttggcaatgg gcgttctggt gtgatcttca ctggcactgc atcagctgga
    82081 tcttttgctg tcgtttttag caaaagtgca actaaatctt gtgcagaata ttcttctaat
    82141 aatttatctg ctgtttgcag gtatttatct agaccatttt ctgcaagttt tgtttcgatt
    82201 tgttcaactg cagcacctaa ttgacctttg aatgcttctt tttcggttgg tggacgtaaa
    82261 gtcgtcatcc gttttttcgt caagttttca atcacatgca agtagtccat ttcatttggt
    82321 gtaacgaaag tcacagacat accgcctttt ccggcacggc ctgtacgtcc gatacggtga
    82381 acgtagcttt ctggatcttg agggatatca tagttgtaca catgagtgac acctgaaata
    82441 tctaatccac gtgcagcaac gtctgtcgct acaaggatat ctaaatgacc gctcttaaat
    82501 gaacgcaata cgctcattcg tttttgttga gacaaatcgc catggattcc ttctgcacgg
    82561 taaccgcgtg cttctaatcc gcgtgccaat tcgtctacac ggcgttttgt acgtccgaag
    82621 acgattgtta attcaggtgt ttgaacatca aacaagcgag tcatgatatc gaatttttcg
    82681 tattcttttg cgcggacata gtattgatcg atcaagtcag ctgtcatttc tttcgctttg
    82741 atcttcacat gatgtggatt tttcatgaat ttaacgccaa tattcttgat agctggcggc
    82801 atcgttgctg agaaaagtaa tgtttgtctt tgatcaggaa cttgtgaaat gattttttcg
    82861 atatcttcca agaagcccat attcaacatt tcatctgctt catccaaaac taatgtttga
    82921 acggttccaa gtttcaatgt gtggcggtta atgtggtcaa gcatacgtcc tggtgtaccc
    82981 acaacgatat gtggacgatc tttcaagcca cggatctgac ggccaatatc tgctccgccg
    83041 taaacggctt gtacacgtac ttttttgtcg cgccctaaac gatataattc ttcttgtgtt
    83101 tggatagcta attcacgtgt tggtgcgata actaaacctt gtaattcgtg acgatctgga
    83161 tcgatttttt ctaacattgg taatccaaat gcagctgttt tccctgtacc tgtctgtgct
    83221 tgtccaataa cgtcttttcc agctaatgct agtggaatcg tttctgcttg gataggcgtt
    83281 gcttcttcaa aaccagcgcg ttcgactgat ttcaacaatt ctggtgataa ttctagttct
    83341 ttaaatttca aatgaatcct cctatatggt tgttaactga ggatgtagct tttttgctac
    83401 cccgtcgatt tgttcggtca aagtgtattg tttctttttg acagtggcca cgcacgtttt
    83461 tatccattct tagcccctgt ggcaccaccg aaaaatcact ttgcgaagtt taggcattag
    83521 aaaagccaaa cgggtcgcgt tcagctttat cattattatg acatctggct tcaacaagtt
    83581 gtttctatgg caaaaccagt ccaatttctc ttcatctttc ggcaataggt tattctaaca
    83641 tagtttttcg ttttctgcaa gtttacagat ttttatttca tttgctgaag ttgttctacc
    83701 acttcaaata agcccatgct gttgctgcct tttagcataa tactatctgt tgcttcaaga
    83761 ttttgtttga tagcatcaat caatttattc ttttcttttt caaaatagaa cacaggtagt
    83821 tgggggtatt tttggttcaa ttcttctttt agtgcatgca tttgttcccc ataaaggaaa
    83881 atcatggcga atttctcagg atcgatatgt tcactcattt gcgcatgcat atttaaagac
    83941 tctttcccta attccagcat atctgctaac acagcgattc tgcgtccttt tgttggcaga
    84001 tttttaaaag tatctaatac cagtcccatg gctgttggat ttgcattgta gacatcgctc
    84061 aaaatagctg caccatttcc tgccgttagc cattcggttc tgttttgagt gatagaaaca
    84121 tgggcgagcc cttggcgtat ctcaggtatg gacagtccaa agaagcgccc gatcgtatac
    84181 gcaatcaaag cattcgttac attataactt ccaggcagcg ggatcgtaaa tgtttctcct
    84241 tctactacaa aatcggtttg tgcttttcct tttgctgtca cttccgcatg aacatcgcca
    84301 tttccaatac cgaatgttgt gactgtttgt actaatgttg ccgttaaagg tgtcagcaac
    84361 ggttcatctg cgggcacaac gagtaatccg tctgatacaa gtccgtcagt gatttccatt
    84421 ttggctttag cgattccttc tcgcgaccca agattttcta tgtgtgcttc accgatcatt
    84481 gtgattgctg cagcttttgg ttgagccata agtgaaagtt ccgtgatttc attggcgtga
    84541 tccatgccca tttccaaaac gatcttttct gtatcttggg gcatgtgcaa aatcgtgtaa
    84601 ggaagaccaa tattattgtt gtaatttcct tgcgtcttat atgttttgta tttttcagac
    84661 aagacagacg cggttagatc tttcgtggtg gttttaccat tgcttcctgt aattgcaacg
    84721 acttctgcgc ctactttttc caagtaatag gttgccaatt gctgcatggc tttcaaagga
    84781 tctgctacag gaataactgg aaaatttttt ggagcttgtt caacaggcaa gctccaaaat
    84841 gaagcagatg ctccgtttgt gatcgcttgc tggataaatt catgtccatc tcgcgtacca
    84901 gcaagaggaa cgaataaact tccttcggtt atcttccggc tgtcaaattc gacattggta
    84961 atctttgtca gtgcagagca ttcgctgccc acggcttgtg caatttcttg tattgttaga
    85021 ttcattgaga tctctcctaa aaaaggttgt gaaaaaagcg tttggcctaa acggcgggtt
    85081 cgcatgactc tcacttccaa gtaaatttct ctattcgtat ttagaagcta gaatgaacgc
    85141 ggttacgcaa tcactccagc ctcttcttta tttctcttta ttcatttttt tcaaaaaaag
    85201 attgacgctg atggtatcga ttcattccta actggatcag ttcttcaatc aaatcaccgt
    85261 atttcaagcc catattttcc cataagagtg ggtacatact gaactccgta aatcctggca
    85321 tagagtttaa ttcattcagg aataattcat ttttatttgt caaaaagaaa tcgcaccggc
    85381 tcaatccgct tccacctaac atcgtgtaag ctaacttcgc gtactcttgc gctttttgat
    85441 aaacttcttc tggcacttcg gctggaatct gcatttcgat tttattattg atatattttg
    85501 cttcataatc atagaatgct acgtctttta cgacttcacc aggcaaagtc gtccgaacgt
    85561 cttcatttcc taatacagca acttcgattt cgcgcgcttc aattccttgt tcaacgattg
    85621 ctcgagaatc atactgatag gctgttgcta aagcattttg cagctcttct cggttttctg
    85681 cttttgtaat gccgacacta gaacccatat tcgccggttt gacaaacatc ggataaagca
    85741 aagaaccttc acattgatca aatacttttt taggattttc tttccattga ttcttaagta
    85801 ctggtacata aggaacttgc ggcacaccag cagcttgtaa aatatacttg gtcatgattt
    85861 tatccatggc acatgcactg gtcaatacgc ctgcgccgac ataaggcata ttcaatgtct
    85921 ctaagaagcc ttggatcgtt ccatcttccc cgtttggccc atgtaaaact ggaaaaacga
    85981 tggctccttc ttctttgatt tcgcccggat tgatcacttt tcctgtaaag ccttcctctg
    86041 tctgtccact tgggtcccat gaaagatgca agacatcttt gctggcaggt ttttctgtta
    86101 gtaatggacc tttgacccat tgtccttctt ttgtaataaa tacgagttga acttggtaat
    86161 aattataata aatggcattt aaaactgaaa atgcggaaag aatggacact tcatgctctg
    86221 cgctgcgtcc gccatatagt aaagtaatct tcaaaagatt gtcctcctgt attctaaatc
    86281 gttcagtgat ttactctcat attttagcac aaaacaaaaa taaacgaata acttatttat
    86341 aaaaaaacga gccagcttct aaaagaacga gcgtcattta ttttttgtca gctagattat
    86401 ttgtcccgtt ttttataaaa agttatgata aagaaaagga gggatgatga tggcgcaaac
    86461 aaatccacgc agccgcttgg cagaaatcat tcgagtgttc atcaattaca atgtagtgcc
    86521 aaactttgta cagcaaaaaa atcccgaaca ggtaaaaaaa gcctttgaag aactaggccc
    86581 caccttcatc aagataggac agatgctttc tgttcgagaa gatttgcttt cttctgcctt
    86641 cactcaaaca ttcaaaacat tacaagatag tgtacctagc gacacatttt caacggtcaa
    86701 aaagacgatc gaaacagaac tttctctttc attatcagat atattcgatg atttttcaaa
    86761 atcgcctttt gcctctgctt ctatggggca ggctcatcgt gccaagctga agaacggtga
    86821 cgcggtagtc gttaagatcc aacaccctaa catcgccgaa gagatccgac ttgatcttca
    86881 actatttgaa cgagcgatcc ctttgatcaa atacattcct gaaactagcg tagttgatct
    86941 aaaaggggta ctccaagaag taaaacgttc cttgatcaat gaaatggact tcttaaaaga
    87001 aagtcaaaat ggcgaacaat tctatcaaaa gaacaatggc tggaaagaga tccgcagccc
    87061 caagatttat gacgcttttt gttcgaaaaa agtgatcgtg atggaagaaa tgtctggtaa
    87121 aaacttgaat catttaatga acgccgaaaa caaaactgaa acttttatca ctggaattca
    87181 aaacaagcag ctgaaacaag aagttgcaaa gcttttagtt gagaacttta tgaaacaggt
    87241 gtttgatgat ggttttttcc atgctgatcc tcatccaggg aatctgctat tccatgtact
    87301 aacaaaagaa gaacagacac aagctagccg aaaaactgaa acagtccatg aaaaagagtt
    87361 cggttccttt gcttttcgag cctccacttc tgcagaagac cctgttgcgc catataccat
    87421 caactacatc gattttggta tgatggggca tctttctgca ggacttaggc aaaaactcac
    87481 acaagccgtt ttagcgctgt atacgaaaga tgcttatcga atcgaaaaag cggtccttcg
    87541 actttgtcag caagaaggct cgtttgatga aagtcggttc caccaagaac tgacaagttt
    87601 tcttgaacag tattatgatt ctcctattga tgaaatcaac ttgcaagaag tattcacaca
    87661 tgtcgtgacg atttgtcatc aaaataatct gcagttcgat cgtgatatca cgcttttgct
    87721 gaaagcattt gggacattag aaggggtgat ccgcgtcctc gatcctgaag tttccctcat
    87781 ggaagtcgct tcgccttttg ctcaacatta ttttctcact catctggatg tagaagatac
    87841 attgaaacaa agcggattag acttattgga agggatgaag gctgcgccta agatccctca
    87901 acagctccac catctattag aaatgtggac ttcgggacaa ggaaaagtca atttggaatt
    87961 gaaaaagcaa gacaaattat tgagcaggat cgaaagtatg atcaatcggc ttgttttcgg
    88021 tatgatttta gctgcattga tcgtagggtc ctccctgctt gtccaagcag cacctgtaga
    88081 aaacgcagag gtcgtttcct tattagggat atttacgtat gctattgccg cattcgtcat
    88141 tatttttttg gcaatcgatg cattgatcca aatgtataag aagaggaaaa agtagaaaaa
    88201 ggttgtgaca gaaagaatca gcttcaagaa ataagaaggg gttttacata aattgtttct
    88261 caaatttttg tgaaaattcg gcttattttt cgaagaggct acttctgaaa caccgagaat
    88321 aaaaaatgtg aaaaagctgt tctgcaccca gtaataagaa caatcaaaaa gggaacatgg
    88381 aacacattta tcctgtttcc ctgttccctt tttgatgtat tcgagcataa ataaaatacc
    88441 ttcgttacct actatcttct gtacttggta aaccttagtc aattgccttt tttaacgctt
    88501 gacgaaaaga catatgatct ttctccgtaa agggttttgg accctttgtc cttatgccag
    88561 cttttcttaa ctttccacta tgataacgtt gttctagaag cgtgccgata ttcgcttcgt
    88621 caaattcttt tccagagtga tggaacactc gcacaccctt cggcaataca agtgaagcta
    88681 aaccataatc ttgcgtgatc aaaaagtcat tcttcttaac cataccgacg attttataat
    88741 ccgcactatc agctccgcgg tctacgtaga cgatttggac atgattagcg tattctttgg
    88801 tcgtataatg gtccacactg gtcacgataa ccacgtcaag accataggat tctcctaatt
    88861 ttatgacatc ttcttttact ggagaaccat ctccatcaat gaatagcctc attctttttc
    88921 gccttcttcc ataaatgata aacagttact aatccgctca gtaaaagacc aacattgatc
    88981 cattttgcca agataagcag ttgtacactt tctatcggca ctgattcatg gttcagcgtg
    89041 atcaataata gatggattgg ctctcccatt tcttttgcta aaacaaacaa aagcgtcatc
    89101 aataaaaact ggtggatcac actcccttta ttttgagtag tatacttgac aacgatccgg
    89161 cgatccattg gaatagctgt atcagtttga taatattcct tatttagcca gctgcctgtt
    89221 actacgtgcc agaaactaag cagaaagaca cctatcgcaa aaccatttgg aatcaagagg
    89281 accaataaag aagaactcag tccaagcaat tgcatagcca atggagacca tgttaaacgt
    89341 ttcaaaatcc atggtccgac tatttttgct gcaatcaagc ctgctgcata aggcaaatac
    89401 ataaaaatcg aaagtttttc taatccgtac agtatgccaa cataaaaact gctaaataaa
    89461 aaaaggaaat tccctagcat tccatttaga aaagtaaaca gatttagcca gcttggcaac
    89521 ttccattcct tcttctggtg tcctaaaaca aacacgaaca agatgaacag cagcaagaaa
    89581 ccataaatag caagatcaaa aagcctttca tcgaataaca atcgggcatt tctcaaaaga
    89641 aacaataagc caaagaatat caaaaataaa acaagctctc gcgtagctac cagatttctt
    89701 ttgatgtctt tgaaatccag ttcgtaacgc ggataatgac taaccgtatg gtaggccatg
    89761 acgtaaaaaa gtgtataaat agtaaagctt gctgcaatct gagtcggtgc aggcaactca
    89821 atcgcttgat acaggagaaa tagccagata gctgcaaata agtacttttt cccatccata
    89881 ttgataaaac cttgcgtctt ttcgtgaaaa ttgaccgtgg tattagcagg tacaagccat
    89941 gctgcactca gccctagcaa aacacttgaa aaataaaata aaggaaaata aaatacgcct
    90001 aatattccaa gcaatgaacc agcaccacca atcagcagag cgatcatcag caacgtgtaa
    90061 ctatctagac caaatcgtag actgttgact aaaaatagtc cagtcatccg aaaggcataa
    90121 aacagcgtaa atggcaaaat cgtcagccaa ttatgcgagt ctgttagtcc caaaaataaa
    90181 agataaggaa taaaaataac cgtgttactt aagataaagg gcgttgtttg tgtaaaatta
    90241 cgcccaaatc gtttgagttt ttcgaacatg acaatggctc cttaaacagt cttataacta
    90301 atctgctctt cgattttagc attaaagggg aaataaacca attttacaga atatattctt
    90361 gtaaaaaaaa atacagaaag aagcataagc ttctttctgc atttttacgg tacttgatta
    90421 ctcaagcaga caagcccttc tccacaaaag tcttgcccga cacccctgca tccggcaggt
    90481 gataaagata gaaatcaatt atcctgtgcc tccaaaatca attaggagct ctgtaaacca
    90541 gagtccttct cgacccgtcg cataaattta ctttaacaca gttcctatgt ttatgcgaga
    90601 gcttttttca ttttataatc gaccatttga aatccttgac cgatatctga aataagttct
    90661 tctgtaatct caaatccttc atgcttataa acctcgattg cttgatgatt cccctgattc
    90721 actcgcaaaa agatctctct ttcctttgtt tgcgcagcaa gttcttcata ccagcgaaaa
    90781 actgaagaag tcaatccttg accacgtact ttatttagca aatataattt acttaaataa
    90841 atttttccat ttatctcttc ataagcagtg taaccgacag tcttttcttc gctttttaat
    90901 aaaaagtagg acacaccttc tgtcagttct ttttgaatct gtttttttga ctgataagtt
    90961 ttcagcatgt aatccacttg tttttgacca atgatcggca caaaaacttc cggccatact
    91021 tcttgtatga ctgccatcag ctcatccagt tcattttctg ttacttttat tttttccata
    91081 cacccacgtc cttttttaca ttataaatga ccttgcgctt gatggaataa aaagagcatg
    91141 atcatgctat acacacccac cgaccacggt ttcaagaaaa tcacaatctg cataaattcc
    91201 ctaaaagata atttcgtcaa accagctact agacagatca agtcgtctgg cgcaaaggga
    91261 agcagcaagg taacaactag tactttttta atatctttcg tttttcttgt cagcaattca
    91321 tcaaatttct gatacttttt tggcgataaa ataagctgga caaaggctac gccatagtaa
    91381 cggacaagca aaaatccgat tgcttcccca atcactaggc caatacaact atataaaagc
    91441 ccaaatccat tgccaaacat cagcatgccc gctactgagg agatccctcc cggcaaaata
    91501 ggaatgatca cttggatcac ttgcaacaga acaaatatca tcactgcata cttgccaaat
    91561 tgctggataa acgcttgcaa agacgtgctc gatcgaaaaa tcccatgatg ataagcataa
    91621 agaatcaaca caaagaaaaa aaacagacca ataatgggca tgatctgaag acatttttgt
    91681 aaaactgatc cttttttaga catctatatt ccccacatct tttttcattt attaaaactg
    91741 cctcctt
//
LOCUS       DAZKNV010000004        80209 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000004 DAZKNV010000000
VERSION     DAZKNV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.004"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(121..1005)
                     /locus_tag="ACG8M1_000274"
     CDS             complement(121..1005)
                     /locus_tag="ACG8M1_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFQ0421023.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(1092..1991)
                     /locus_tag="ACG8M1_000275"
     CDS             complement(1092..1991)
                     /locus_tag="ACG8M1_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFQ0421024.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            complement(2008..2514)
                     /locus_tag="ACG8M1_000276"
     CDS             complement(2008..2514)
                     /locus_tag="ACG8M1_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFQ0421025.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            complement(2703..3323)
                     /gene="rpoE"
                     /locus_tag="ACG8M1_000277"
     CDS             complement(2703..3323)
                     /gene="rpoE"
                     /locus_tag="ACG8M1_000277"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFQ0421026.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            complement(3399..3836)
                     /locus_tag="ACG8M1_000278"
     CDS             complement(3399..3836)
                     /locus_tag="ACG8M1_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFQ0421027.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            3999..4829
                     /locus_tag="ACG8M1_000279"
     CDS             3999..4829
                     /locus_tag="ACG8M1_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFQ0421028.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            4813..6180
                     /locus_tag="ACG8M1_000280"
     CDS             4813..6180
                     /locus_tag="ACG8M1_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0421029.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            6199..7008
                     /gene="yidA"
                     /locus_tag="ACG8M1_000281"
     CDS             6199..7008
                     /gene="yidA"
                     /locus_tag="ACG8M1_000281"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFQ0421030.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(7051..7494)
                     /locus_tag="ACG8M1_000282"
     CDS             complement(7051..7494)
                     /locus_tag="ACG8M1_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFQ0421031.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            7628..7999
                     /locus_tag="ACG8M1_000283"
     CDS             7628..7999
                     /locus_tag="ACG8M1_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0421032.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            complement(8168..8950)
                     /locus_tag="ACG8M1_000284"
     CDS             complement(8168..8950)
                     /locus_tag="ACG8M1_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFQ0421033.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(8947..9918)
                     /locus_tag="ACG8M1_000285"
     CDS             complement(8947..9918)
                     /locus_tag="ACG8M1_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFQ0421034.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            10010..11404
                     /locus_tag="ACG8M1_000286"
     CDS             10010..11404
                     /locus_tag="ACG8M1_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFQ0421035.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            complement(11596..12951)
                     /locus_tag="ACG8M1_000287"
     CDS             complement(11596..12951)
                     /locus_tag="ACG8M1_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFQ0421036.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(12981..13616)
                     /locus_tag="ACG8M1_000288"
     CDS             complement(12981..13616)
                     /locus_tag="ACG8M1_000288"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFQ0421037.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            complement(13623..14999)
                     /locus_tag="ACG8M1_000289"
     CDS             complement(13623..14999)
                     /locus_tag="ACG8M1_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFQ0421038.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            complement(14992..16773)
                     /locus_tag="ACG8M1_000290"
     CDS             complement(14992..16773)
                     /locus_tag="ACG8M1_000290"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFQ0421039.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            complement(16795..17106)
                     /locus_tag="ACG8M1_000291"
     CDS             complement(16795..17106)
                     /locus_tag="ACG8M1_000291"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFQ0421040.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            complement(17096..18082)
                     /locus_tag="ACG8M1_000292"
     CDS             complement(17096..18082)
                     /locus_tag="ACG8M1_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFQ0421041.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            complement(18097..18681)
                     /locus_tag="ACG8M1_000293"
     CDS             complement(18097..18681)
                     /locus_tag="ACG8M1_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFQ0421042.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            complement(18702..19172)
                     /locus_tag="ACG8M1_000294"
     CDS             complement(18702..19172)
                     /locus_tag="ACG8M1_000294"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFQ0421043.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            complement(19191..21194)
                     /locus_tag="ACG8M1_000295"
     CDS             complement(19191..21194)
                     /locus_tag="ACG8M1_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFQ0421044.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            complement(21181..21513)
                     /locus_tag="ACG8M1_000296"
     CDS             complement(21181..21513)
                     /locus_tag="ACG8M1_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421045.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     misc_feature    complement(21613..21660)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            21850..22569
                     /locus_tag="ACG8M1_000297"
     CDS             21850..22569
                     /locus_tag="ACG8M1_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFQ0421046.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            complement(22899..24797)
                     /locus_tag="ACG8M1_000298"
     CDS             complement(22899..24797)
                     /locus_tag="ACG8M1_000298"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFQ0421047.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(24958..26220)
                     /locus_tag="ACG8M1_000299"
     CDS             complement(24958..26220)
                     /locus_tag="ACG8M1_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421048.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            complement(26213..27112)
                     /locus_tag="ACG8M1_000300"
     CDS             complement(26213..27112)
                     /locus_tag="ACG8M1_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421049.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            complement(27257..29035)
                     /gene="uvrC"
                     /locus_tag="ACG8M1_000301"
     CDS             complement(27257..29035)
                     /gene="uvrC"
                     /locus_tag="ACG8M1_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFQ0421050.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            complement(29217..29531)
                     /gene="trxA"
                     /locus_tag="ACG8M1_000302"
     CDS             complement(29217..29531)
                     /gene="trxA"
                     /locus_tag="ACG8M1_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFQ0421051.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(29618..31978)
                     /locus_tag="ACG8M1_000303"
     CDS             complement(29618..31978)
                     /locus_tag="ACG8M1_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFQ0421052.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(32093..32641)
                     /locus_tag="ACG8M1_000304"
     CDS             complement(32093..32641)
                     /locus_tag="ACG8M1_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFQ0421053.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            complement(32699..33136)
                     /gene="zapA"
                     /locus_tag="ACG8M1_000305"
     CDS             complement(32699..33136)
                     /gene="zapA"
                     /locus_tag="ACG8M1_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFQ0421054.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            33338..34255
                     /gene="rnhC"
                     /locus_tag="ACG8M1_000306"
     CDS             33338..34255
                     /gene="rnhC"
                     /locus_tag="ACG8M1_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFQ0421055.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(34633..35544)
                     /locus_tag="ACG8M1_000307"
     CDS             complement(34633..35544)
                     /locus_tag="ACG8M1_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFQ0421056.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(35945..36523)
                     /locus_tag="ACG8M1_000308"
     CDS             complement(35945..36523)
                     /locus_tag="ACG8M1_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0421057.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(36543..37211)
                     /locus_tag="ACG8M1_000309"
     CDS             complement(36543..37211)
                     /locus_tag="ACG8M1_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421058.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(37226..38296)
                     /locus_tag="ACG8M1_000310"
     CDS             complement(37226..38296)
                     /locus_tag="ACG8M1_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421059.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(38467..39831)
                     /locus_tag="ACG8M1_000311"
     CDS             complement(38467..39831)
                     /locus_tag="ACG8M1_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFQ0421060.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(39828..41387)
                     /locus_tag="ACG8M1_000312"
     CDS             complement(39828..41387)
                     /locus_tag="ACG8M1_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421061.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(41443..43923)
                     /locus_tag="ACG8M1_000313"
     CDS             complement(41443..43923)
                     /locus_tag="ACG8M1_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421062.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            complement(43907..44242)
                     /locus_tag="ACG8M1_000314"
     CDS             complement(43907..44242)
                     /locus_tag="ACG8M1_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421063.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(44256..45290)
                     /locus_tag="ACG8M1_000315"
     CDS             complement(44256..45290)
                     /locus_tag="ACG8M1_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFQ0421064.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(45380..46060)
                     /locus_tag="ACG8M1_000316"
     CDS             complement(45380..46060)
                     /locus_tag="ACG8M1_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0421065.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(46230..47189)
                     /locus_tag="ACG8M1_000317"
     CDS             complement(46230..47189)
                     /locus_tag="ACG8M1_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0421066.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            47433..48836
                     /locus_tag="ACG8M1_000318"
     CDS             47433..48836
                     /locus_tag="ACG8M1_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0421067.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            49185..49817
                     /locus_tag="ACG8M1_000319"
     CDS             49185..49817
                     /locus_tag="ACG8M1_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFQ0421068.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            50405..51844
                     /locus_tag="ACG8M1_000320"
     CDS             50405..51844
                     /locus_tag="ACG8M1_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0421069.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            52139..52357
                     /locus_tag="ACG8M1_000321"
                     /pseudo
     CDS             52139..52357
                     /locus_tag="ACG8M1_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            52606..52821
                     /locus_tag="ACG8M1_000322"
     CDS             52606..52821
                     /locus_tag="ACG8M1_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421070.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(53038..53294)
                     /locus_tag="ACG8M1_000323"
                     /pseudo
     CDS             complement(53038..53294)
                     /locus_tag="ACG8M1_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(53481..54392)
                     /locus_tag="ACG8M1_000324"
     CDS             complement(53481..54392)
                     /locus_tag="ACG8M1_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0421071.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(54411..55415)
                     /locus_tag="ACG8M1_000325"
     CDS             complement(54411..55415)
                     /locus_tag="ACG8M1_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFQ0421072.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(55412..57535)
                     /locus_tag="ACG8M1_000326"
     CDS             complement(55412..57535)
                     /locus_tag="ACG8M1_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFQ0421073.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(57540..59987)
                     /locus_tag="ACG8M1_000327"
     CDS             complement(57540..59987)
                     /locus_tag="ACG8M1_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0421074.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(59974..60363)
                     /locus_tag="ACG8M1_000328"
     CDS             complement(59974..60363)
                     /locus_tag="ACG8M1_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0421075.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(60423..60926)
                     /locus_tag="ACG8M1_000329"
     CDS             complement(60423..60926)
                     /locus_tag="ACG8M1_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFQ0421076.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(60939..61163)
                     /locus_tag="ACG8M1_000330"
     CDS             complement(60939..61163)
                     /locus_tag="ACG8M1_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421077.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(61267..63177)
                     /gene="ltrA"
                     /locus_tag="ACG8M1_000331"
     CDS             complement(61267..63177)
                     /gene="ltrA"
                     /locus_tag="ACG8M1_000331"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFQ0421078.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(63923..64060)
                     /locus_tag="ACG8M1_000332"
     CDS             complement(63923..64060)
                     /locus_tag="ACG8M1_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFQ0421079.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(64057..65241)
                     /gene="mobT"
                     /locus_tag="ACG8M1_000333"
     CDS             complement(64057..65241)
                     /gene="mobT"
                     /locus_tag="ACG8M1_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFQ0421080.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(65500..65790)
                     /locus_tag="ACG8M1_000334"
     CDS             complement(65500..65790)
                     /locus_tag="ACG8M1_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421081.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(65780..66922)
                     /gene="dcm"
                     /locus_tag="ACG8M1_000335"
                     /pseudo
     CDS             complement(65780..66922)
                     /gene="dcm"
                     /locus_tag="ACG8M1_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(66998..67162)
                     /locus_tag="ACG8M1_000336"
     CDS             complement(66998..67162)
                     /locus_tag="ACG8M1_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421082.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(67155..67829)
                     /locus_tag="ACG8M1_000337"
     CDS             complement(67155..67829)
                     /locus_tag="ACG8M1_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFQ0421083.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(67907..69247)
                     /locus_tag="ACG8M1_000338"
     CDS             complement(67907..69247)
                     /locus_tag="ACG8M1_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFQ0421084.1"
                     /translation="MYKGHRIRAGDQHLVYHFVIGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(69330..69665)
                     /locus_tag="ACG8M1_000339"
     CDS             complement(69330..69665)
                     /locus_tag="ACG8M1_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFQ0421085.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(69675..70049)
                     /locus_tag="ACG8M1_000340"
     CDS             complement(69675..70049)
                     /locus_tag="ACG8M1_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFQ0421086.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(70062..70376)
                     /locus_tag="ACG8M1_000341"
     CDS             complement(70062..70376)
                     /locus_tag="ACG8M1_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFQ0421087.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(70489..73716)
                     /gene="fss3"
                     /locus_tag="ACG8M1_000342"
     CDS             complement(70489..73716)
                     /gene="fss3"
                     /locus_tag="ACG8M1_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFQ0421088.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            74573..74827
                     /locus_tag="ACG8M1_000343"
     CDS             74573..74827
                     /locus_tag="ACG8M1_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421089.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            74991..75908
                     /locus_tag="ACG8M1_000344"
     CDS             74991..75908
                     /locus_tag="ACG8M1_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0421090.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            75901..76683
                     /locus_tag="ACG8M1_000345"
     CDS             75901..76683
                     /locus_tag="ACG8M1_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0421091.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            76684..77364
                     /locus_tag="ACG8M1_000346"
     CDS             76684..77364
                     /locus_tag="ACG8M1_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0421092.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            77357..78253
                     /locus_tag="ACG8M1_000347"
     CDS             77357..78253
                     /locus_tag="ACG8M1_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0421093.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            78465..>80209
                     /locus_tag="ACG8M1_000348"
     CDS             78465..>80209
                     /locus_tag="ACG8M1_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0421094.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGID"
BASE COUNT        23398 a        16523 c        14089 g        26199 t
ORIGIN      
        1 aaaattggtg gacagttttt tgttgtacct gtatagatat tgttaagcct ttgcaagtaa
       61 ggtagttatg tgttcaacta cttattaaaa tgtgttattt attaaagata cttgtctcac
      121 ttactgaact ggccgatgat cgtttctgcc ataatagttc tcgacagccg ttggatgccc
      181 taataaatcc ccaactgtcg tgatgcgata cccttgctct ttcagataat cgatcacttg
      241 aggaacggca cgaatcgttt caggatagat atcatggaat aaaataattg ccccatcgta
      301 tactgttgct tggatcttct gcaaaatcaa atcaggattt cttgtcttcc aatcttctga
      361 atcaacagac cattcgatga tcggtcgctg gatgatcgtt gctcctacat tcgtgacaga
      421 accatagggc ggacgaacaa aagtgggggt tttgccagtg acttttttga tctcagtgtc
      481 tgctttcgtc acttcctccg tcatcgactg ggcagaaaga gtggccagat tctgatgatc
      541 gtatgtgtga ttgccaatct cgtgccctgc ttcagctgtc tgcttcacga tttcaggatg
      601 ctgcgccgta ttttctccta agacgaaaaa agtggcatgc acgttttttt cttttaagat
      661 tcgcagaagc tgcggtgttg tggtcgctcc tggtccatca tcaaagctga ttgcgacgct
      721 tttgacagcc ggatctcggc tcgtttttgt actgtcttgt gttgattgtg atgactgact
      781 ttgtaccttt tccgctgatt cttgaatggc ttctttgacg ttagctgttt cagttgattg
      841 gcttttaatg gttgattgtt ctgattgttt gaaagattgt gacgaatgct ccgaagagtg
      901 tgtttgtcct tttacttcgg tgatcaagga ggccaccgaa gtaatttcga aaaacaaaag
      961 cacggataaa gcaataatac tgataactaa ataatttctt ttcactatat ctcttctttc
     1021 tctttttctc ttcttattat ttacttgtac ttacttgaaa attgaaactg ctagtcgcaa
     1081 ctacttctcg tctaatgatc caaataatct tccgatgcca aaatcgtttt tgtcacggac
     1141 ttaggaatga caaattctgg tgtacccata taaccaggag caatttcgta ttgagaaaaa
     1201 gtcaaaacta attgatgctc tttgttcaaa taaaaacttc gtgtaggcgt aacaagtgtt
     1261 ggtttttcta tcgtcccttc ttgaatatct tgctcagtcc aatagtactt agatggatct
     1321 tccttgactt gttcggccat ctgccgtttg acttcttttg tcaaaacaga tagataggtg
     1381 tcatctttga ataaaagtgg aagtgagagc tggacactgt ttttcttgtc gattgtgtcg
     1441 tatctttttt caacatggct atctgctgct gtttgggtga tctgcctttc aatcacgaga
     1501 aaccggttat cgtctacgat tttctgataa tctcccaaaa cttggtaatg atccgtttca
     1561 aaatttccat attctttttc agctttttca aaatctgctt gtccttcgcg aaagtatttt
     1621 tgatttaatc catgaattgt tttattttct ttctcatttt gtgtattgat cttcggtacc
     1681 tgaatatcga ttttttcaga tcgatcagta aagcgttcgc ctaagatcaa ttcaatgact
     1741 gatcctaaga tgggtaaatc ttctgcaaag cttcgaactt gactattaaa aagaaggcta
     1801 cttgttgtaa tcattacgat agccaaagat actccgaacc cttggagacg tctctttctc
     1861 cgctttgctt ttataaatga ttgctcttcg ataataaaac gctggcggat ctcctcttta
     1921 agccctttgg gaattgcttg ttctttataa gttttcttta gtttttttaa attttctttt
     1981 tgggaataca tggcactctt ctctccttca ttctaggatt tgacgtaaag cattcaatga
     2041 gcggtacatt ttcgttttaa ctgtgttttc attcatatcc aagatagtcg caatttcttt
     2101 caaacgaaat ccttcaaaaa agtagaggat cagaatctct ttttccggac tgtctatttt
     2161 atctaaaatc atatggagct ctgcaacgga agtttctaaa ggtaactgtt gggggatatc
     2221 ttgaatttca aataagtcca caggcgtcct tttttgtctg cgccaactat ctaatgccgt
     2281 gcggatcaat atccgataaa accatgcact aaaatgctcg atctcttttt ctttttcaaa
     2341 atagttcagg gctttatgaa aactatcttg catcacatct aaggcctctt ctttatcatg
     2401 tacgtaattc atcgtgatac ggaacatttt ttgataatca gtttcgatga gtccattcag
     2461 caggtgacgg tatttttcga tctgccgttt tttcttatat ccagtaaaaa tcattctcca
     2521 ctcctttctg cctcacttaa tatgacgtac aaggtgcgct aaaagtttca atttttttat
     2581 tttttatgta tttacttggg atttttatat acaaaaaaga aggtgtgaca aaaatcgtgt
     2641 cacacctcct tattctgata ggctgatcgt ctctgtcaca acctctcgta agaaaataat
     2701 gtttattctt tttcagagtc agaaaattct tcctcttcat aatcttcatc atcatcgtct
     2761 tcgtctatga tacttaaatc ttcttcgata tttcctggca agtcttcttc atcatctgtc
     2821 gggtcatctg ctccgatttc ttgcaagtca gaattataag cagcgatttc ttcatcttca
     2881 tcatcatcgt catcaaacag atcatcgtca tcttcttctg tcagatctgt atcttctggg
     2941 tcatcgtcat tgtaatcgat cgcgtcttca tcatcattga taaaggcgtt gactttcttg
     3001 cgtttacggc gacgtggagt atcttcatcc tcttcgtcca ttccatggtt tacttcttca
     3061 tcgatcgaat cgatagcata ccatgaacgc aagccccaac gattatcccc taatgagata
     3121 aagctgccgt caatattcaa gtcagtataa aattgtgcga gtgaatcacg aatttcactg
     3181 tctgatttcc caagatagtt ttggatctgg ttagctaaat cagaaaaatc catgacatcg
     3241 ccacgttgtt ctaagatcgc gtgtgctact tcgatcattg ataattcgct tttgtttgca
     3301 ccttcaaata cactaatttc caatcaggac acgtcctttc acagtctact ccttatcata
     3361 caaaatcaga cacaaaaaat caaacttttc ttttatattt acgctgtaaa atccaaggtc
     3421 aaataatatt cgccgatttt ttccggtccc atgaacagat cataatcgat tcgaaccttc
     3481 cctgctgtgg gacggtcttt caaactaaca tgcagttctt tcgtaaaagt agcaatctgg
     3541 atcataccgt atggtgttcg ataggatgtt tctaaccgtt ctttatagcc aaatttcaaa
     3601 cgcatccgca tttctcctgc acggatcagc tgtacatgac catctggaac taatttgatc
     3661 gttacaggaa tctcatcgcc cgtctcctcc tgaatctctt tataacgtat gtacagcgta
     3721 tcgccaattg tcaccatttg ccctttcaaa tcaaaataaa aatcttgcac ttccccttgc
     3781 tgttttactt ttgtacgcaa tttgattgaa atcggtgttc cttgtgataa ttccattatt
     3841 cattctcctt tacttctcat agctacattg ttcctagttt cttttgtttt gtcaaccaac
     3901 ttgtccattt ttacagaaaa ccttttttcc aaaacaactc tttgatttta gagtataata
     3961 ttgtagaaaa tatgaattta tacaaaggag ccggttgaat gaaccctgcg attcgactag
     4021 atcagcacat ttatcaaaaa aacgactttt ccccttttgc attaacagat atattaacgg
     4081 aatattctaa agaacaccag caaatctttt tacatttctg gcaatatgac tgcacagtca
     4141 tcttaggtat gaaggatgtt cgaactcctt ttctaagtga cgggatccaa acactggaag
     4201 atgcaggtta cgctccagtg atcagaaatt caggtggatt agggatcgta tcagatgaag
     4261 gaattttgaa tatttctttg attttccccc aaagtgacac aaaaaaaata accatagatg
     4321 acgcttacga gcaaatgctc ctattgacta aatacgcttt tccaaaggca ccgatacaag
     4381 cattcgaaat cacccattct tattgtcctg gaacttatga tttaagcatc catggcaaaa
     4441 aatttgccgg tatcgctcag cgtcggatca aaaatgggat ttctgttatg atgtacttaa
     4501 gtgtcaacgg taatcaggaa aaacgtgggc aagtcatgaa gcgattttat caatctgctt
     4561 taaaagaaga ctttggtaca aatggctatc ctgcagtgga tcctgctaca atggcaacac
     4621 ttgaagaact gcttgaccaa cccctttttg taaaagaagt caaagaagca tttgcaaaag
     4681 cttttgaaaa gctgtattct gcaagtgatt tacaggattc taccgactgg ctaaaaaaag
     4741 aaatccagct ggagcaatgg aacaaccaaa tccagagaat ggaacaacgt aataacataa
     4801 aggagctaca ttatgacaac cccttataaa tatcaaatgc tgcctatgga aaaagttttt
     4861 cgtgatccag tccataacta tatccatgtc cagcatcaag taatcttaga tttgatcaat
     4921 tcgaaagaag tccaacgtct acgacgcatt aaacaattag gcacttcttc tttcactttt
     4981 cacggagcag aacatagccg ttttactcat tcattaggcg tttatgagat ttcaagacga
     5041 atctgcgata tcttttctcg aaatttttca aaagaaaaaa taggcaacgg aggctgggat
     5101 gatcaggaac ggctggtgac tttatgtgcg gcactgttgc atgatgtcgg tcatggtcct
     5161 tactctcata catttgaaca tatcttccat acgaatcatg aagccatcac tgtagagatc
     5221 atcacttctc cagaaacaga agtgtatcag attcttaacc gagtagaaga aggttttcct
     5281 gaaaaggtag ctagtgtgat ccaaaaaact taccccaacc cacaagttgt ccaaatgatt
     5341 tctagtcaga tcgatgcaga tcgaatggac tatttgcttc gggatgctta tttcactgga
     5401 acagaatatg gaacatttga tcttacccga atattacgtg tgattcgtcc ttatgaaggc
     5461 gggatcgctt tttccatgag tggcatgcat gcagtggaag attatatcgt tagccgatat
     5521 caaatgtatg tgcaagtgta cttccatcct gtttcccgtg gtatggaagt aattttggag
     5581 catctgcttc atcgcgcaca cgagttgtat caagaagatg ccagcagttt tgaactccat
     5641 tctcaattac ttctgccatt tcttgacgga agctttactt tagaagaata cctcaaactt
     5701 gatgatgggg tcttgggcac ttactttact caatggtctg aatctgctga tcctatttta
     5761 aatgatttag ctaaacgttt tttgaatcgt aaaccactga aatctgctac tttttctggc
     5821 aaccgggatt caaaattagt ccaagaactc actttgttag tagaaaaggt cggatataat
     5881 cctgtttatt acactgctgt gaattctagc tacgatctac cttatgattt ttatcgccca
     5941 gaacaaggca gacatcgcac acaaatcgag attttgcgaa atgacggaac tttgatagaa
     6001 ttatcacagg ttagtcagct tgttgctgca ttagcgggac aagaacaagg agatgagcga
     6061 tttttctttc caaaagaaat ggttgatccg tccttgcgtg atcattatga tttatttgac
     6121 gaaacttatc aagaatttgc cagccatatc cgtaatggcg cattgattga aataaattaa
     6181 aatatattgg aggaaattat gtctatcaaa ctagtcgcta tcgacatcga tggtacttta
     6241 ttaaatgaga aaagagaagt aacaaaagaa gtaaaagaag cgattgccgc tgctgttgca
     6301 aaaggtgttt cgatcgtttt atgcactggc cgtcccttac caggtgtcca ggaacagtta
     6361 aacgagttga acctttttca agataatgat tacgttatta cttataacgg ggcactcgta
     6421 caacaaacga aatcaggtaa aatcatcgcc cgtcacggac tgacacatga agatttccta
     6481 gagatcgaag taatggcacg ccgtgtcggc agtcatctcc attcgatcga tgacaaagcg
     6541 atctacacgc ctaatcgaga tatcagcgct tatacgatcc acgaagcaag tttagtcaag
     6601 atgccgctaa aatatcgaac acctgaagaa atgacaccag acatgaacat cgtcaaaatg
     6661 atgatgatcg acgaaccaga aattttagat gcagcaattg cgcgtttacc gcaaactttc
     6721 cgtgataaat acacaacggt caaaagtgcg ccctattact tcgaagtact aaataaagaa
     6781 gcaagtaaag gtgcggcagt tgcgaatctc gcacagcacc ttggtattga tcaagatgaa
     6841 atcatggcta tcggagataa cgagaacgac ttatccatga ttgaatatgc tggtctagga
     6901 gtagcaatgg gaaatgccgt ttctcttgtc aaagaagcag caaatgtcat cacttcatca
     6961 aacgacgagc acggtgtagc tgaagcaatc aaaaaatatg tactgtaata aataaaaaaa
     7021 ctgagagaaa gctgatctac tcgctttctt tcagttttta tttttttcga tccatctctc
     7081 gactgcccat cggtggctac cacgtttcaa tttcacaagc gcttcttgag ggctcaccca
     7141 ccaaatttta ttggtctttt cagttggttc tcctatacgc ttccaagaat cagcaacaaa
     7201 gaaatatcct ggattataat aataagttgc acgataattc gagtaaaaat actcatcagc
     7261 ttctcccaga taagaagaaa tttctgccac aattcccatt tcttctatca gctcacggac
     7321 aatcgcttct tctttcgtct cttctccttc aatttccccg ccaggaagaa aaaaagcacc
     7381 atttggagcc tcgattactg caatctgctg atctctttct atgacaatat atgctgcata
     7441 acgggtttga taatcagcaa attgcttttt ttcaccaaaa attggtttat ccatgaatag
     7501 tttccacctt aacagtttta ttttctatcc attttacatg agaaatttct catgaacaag
     7561 cacaaatcaa ctatttcctt acttcttttt gttatgattg agtaaaagga aaaggagaga
     7621 tgaatctatg aaaatggctc acacatgtgt tcgagtgaaa gatcttgaag catcaatcga
     7681 attttatcaa aaggcatttg gttttgaaga aagccgccgc cgtgattttc cagaaaacaa
     7741 atttacactt gtttatttga cacttcctgg ggatgactat gaattagagt tgacttacaa
     7801 ctatgatcat ggtgcgtatg atctaggaga cggctatggt catatcgcta tagcagctga
     7861 tgatctagaa aaattacacg agcaacataa agctgctggt cttgagatta ctgacttaaa
     7921 aggattacct ggcactgcgc cttcttacta ctttgtcatt gaccctgatg gttataaaat
     7981 cgaagtcatc cgaggatagt tagtatgggg cattttactc ttgattgaat aaaaaacaaa
     8041 caccaataat taaaatgaga cgcaaacttt tcattaaatt gaaaaagttt gcgtcttttt
     8101 ttaacaacca ttgtagctat aaggttgcca ctctccacca atttattttt aattcatttg
     8161 aaagaaatca aataaacgag gtacctttag aaaacaaaac tgcttttcct cctattatca
     8221 cacgatcttc ttttaattca cattctagat ccccgcccct tgatgacatt tgataagctg
     8281 acaattttgt tttattcatt ctttctgccc aataaggaat aagattagaa tgtgctgatc
     8341 cacatactgg atcttcattg attgttaatt ttggaaagaa ggttctagaa acaaagtctt
     8401 tttgcacact ttctgctgtc acgatgactc ctattcctaa ttcaaaattt ttgatagctg
     8461 taaaatctgg ctgcaattta gccaccgttt tttcatcttc taatacgaaa aataaatcac
     8521 gtgctaagta ggcttcttta atcttagccc caatcgcttc ttcatattca gacaatatcg
     8581 gcactttttt cggcataata ctaggaaaat ccatgtaata ataatcttta attcttgtca
     8641 caaatagatt accgctttga gtagaaaatt taatcgtttc atcaggtatt ttgtaatagt
     8701 taaataaaac aaatgctgtt gctaatgtcg cgtgaccaca aagatcgatt tctcgatctg
     8761 gcgtaaacca tctaagctca aattcttggt ttttcttcac tgtaaatgct gtttcagata
     8821 aattgttttc aatggcaatt ttttgcatcg taccttctgg cagccattct tctagcacat
     8881 aaaccgctgc tggatttcct ttgaacacct catctgcaaa tgcatcaact acgtaataat
     8941 ctaagttcat tttaaagccc ctttctctaa tttgttataa atatattctg cacaacaaag
     9001 atcttcaata gctagaccaa ctgcgtcgaa aatcgtcggc ctcgattctc ctttataaaa
     9061 tgtttttttc tcagaaacta attcgcctaa tgtaccaaca atacaagatt cctctaaatc
     9121 tccttctgcc atggctataa gcaggtcccc gctttctgtt aaggcagctg agtaatcatc
     9181 tacatagatt tgagaagttt ccatcaacga tgtacttatc tctcttgtat caggagtaaa
     9241 tgtgcccaca gcattgatat gtgcgtcttc ccttacccac tctttttgaa gaaatgcctc
     9301 tttactagag gtcaacgtac aaatgatttc cgctggacgt actgcatctt ctactgatat
     9361 tgcatttata aacgttattt taggatactg ttttttagct ttagcgataa aagtatttcg
     9421 tctttcttct aaaatatcgt aaacaaacac tgtagtgatg ggacgaatgg tagaaatcgc
     9481 agtcaaatgc gacaatgctt gttgaccagc tccaattaaa gcaagtgttt ctgcatgcgg
     9541 atttgctaag taatctgttg ccagcgcaga tacagcagct gttcgaatcc aggtgactgc
     9601 atttgcgttt atcaatgctt tgggtagtcc gttttgagca tcaaacaaga aaatctctcc
     9661 taaatgagaa ggtaaatgat actgatgatt atccggaaaa gcggtaatga cttttgtgcc
     9721 aaaatatctg ttctccccca aataagcagg catcatcgca aacatatttt tgccttttcc
     9781 gtcaggtaaa atttccacca atcgaggatt ttggctgatt ttaccacttt cataatcaaa
     9841 aaaacatttt ttcattactt gaatcgcttc ttcaaaacta aaagaagcta ctacttcctc
     9901 aaaattaata attttcatag acaattccct cctcacaaaa gattaacttc taaaatcaat
     9961 acaatcaatg gtaaaattgt atggtataca attttaagga gtggagaaaa tgcctattaa
    10021 ttcttatgac aattacccgt taacttggcg accagacaaa caaaaattga agcgtcctta
    10081 ttatcgatcg ttgattcaac aattagaaca agatatttta aagaataaat tacagaaaaa
    10141 cactcagtta ccctcccaaa gagagctagc tgattattta gatttaaatt ttactaccgt
    10201 tggcaaggct tataaatatg gaattgagaa aggtttgctg tatacgaata ttggaagtgg
    10261 cacatttatt tctcccaatg tctttgagtc catcaccatc tctaccaatg aagtaaccga
    10321 acatatcatt gattttggtc tggttagttc ttttgaagaa tgtaataaat tcgttgtccc
    10381 gtttattcaa tcaactagta ataacccaaa tcttgttggt ttgcttaatt accaagatcc
    10441 caaaggcaca aattttcaat tgactactgc agcaaattgg ttaaaaactc aaggagtcat
    10501 tccgtcctta gaatctctat ctattgtttc cggtgttcaa aatggattgg ctatcacact
    10561 ttctgcactt ttctctccag gtgatagaat agcaacagac cgatatacat acgctaattt
    10621 cattgaattg gctcagttat atcatttaga gatcgttcca attgattttg acgagcaagg
    10681 aatgcgacct gatatattga ttcaggaatg tagaaaaaag aagattcatg gtgtctttct
    10741 tatgccttct tgtaataatc ctatagggtt tcaaatctct cacaaaagac gagagcaatt
    10801 agccgaagtg attgaaaaag aaggtctatg ggttattgaa gatgatatcc attcattttt
    10861 aacaacttac tatcaacata cgatcattcc tcctttccaa aatttattac ctaaccaaac
    10921 aatctactta gctggaatga caaaatttat ttgttctgga ttgcgagttg cttatcttgt
    10981 agttccagta catgtccaaa gcaagataga acaagcaatt tttaatataa atgtgaaaac
    11041 ttctggatta gatgtggaag tcatcactca aatcctccat tcaaatgaag caaataggat
    11101 cttagaaact aaattaagtc ttacaaaaag agccaatcag ctttttgatt ctcttttcaa
    11161 agtagaaaaa ccaacgaatc gtgtccctta ctatcgaatt cttccagttg atcctgagat
    11221 tgaccctaag ataattgaga atgactttct tgctaacggt atccgacttt atcattccag
    11281 acgctttact acacgtgcgc aaccagatgc attcgttcga atttccctat cctctaataa
    11341 ccttgaaatt ttagcttctg gactaagtat cgtaaaagaa aaaataaaaa aatatgaatt
    11401 ataacctatt gataaataaa ggaatcaaat cttattgatt cctttcaata aaaaagaggc
    11461 actacccgag gttcaacaac gggtagtgcc tcaaaaaata aacgaacatt ttgcacttaa
    11521 agtatccaag aagcaagaaa aattatttta ttttcttatt ttactaaatc actaggtttc
    11581 tgtcagaaga tgaaattatc caatcatgac actttcttct ggatatttgt attttgattg
    11641 tgttctttgt gcttttgtca tcagagagaa gaccacagtc aatacaccaa ctcgtccaat
    11701 gtacataagc gctataatga tcaatttccc tattgcagtc aagtctggcg tcaatcccat
    11761 cgtaagacct actgtaccaa acgcagagaa gacctcaaaa gcaatatatt cgatgccaga
    11821 agttttaggt atcgtttcag tcaccgataa aatcatgatg gcgactacac acaacgtcaa
    11881 cgtaacaaaa aataaagtaa gtgcccgcaa cactgcgcct tgtcggatgg tacggccaaa
    11941 tgcttccgct ctcgtacgtc ctttcaacat cgaacgcatc tggatcagca acacacctaa
    12001 cgtagttgtt ttcaatccgc cggccgtcga cccagatgtt ccgccgatgt acatcaaaaa
    12061 catcgttaaa atcagacctg catggctcat atggaggtaa tcaactgaat aatatccagc
    12121 cgttctaggt gtcacactca taaaaaaggt gtttgccaat cgttgaaaca tattcccttc
    12181 cactagcgtt gccccattgc gctctgtgaa aaagaacaca acgaatccgc ctaataaaag
    12241 ggtacctgta acggttaatg cgatttttga atgaatcgtc atcttctttt tctgatgata
    12301 ttccagtaaa tcacgccata cgatgaagcc taacccacca gaaatgatca aagcagatac
    12361 caccatgatc aaataaacat tttgctggtg attggctaaa ctgtctccta acaaatcaaa
    12421 ccctgcatta caaaaactag agattgcatg gaacaaactg taccagatac ctttcaacca
    12481 gccaaattca ggcacaaata caaaagataa agcaaccgta ccaatcaatt ggatcacaaa
    12541 ggccaatttt aggatgtaaa gcatgagctt catcacacct gatacttctt ctagattcag
    12601 cgcttctttt aatataatac gtgtgctgag actgactttc ttctttatca atgcaaagca
    12661 tagaatcgga accatcataa aaccaagacc gccgatctca atcaaaagca tgatcaaaaa
    12721 ttgaccagca ctgttccaat gctctgctgt attcaatgtt gtcaatcccg ttacacagac
    12781 agcagaagtt gcagtgaaaa gcgcatcgat aaaatttgtc ccatgcccac tattactaaa
    12841 aaatggtagg gtaagtaggc cgccgccaac taaaatcagg agaaaaaatc ctaatgcgag
    12901 aagctgaaca gccggcaaac gtttctttat ttgtttgctt tgtttaatca tcgttttcct
    12961 cttttaaaaa aagataccac ttagtcagtg gtacccatat tttttacttt gatcaacctt
    13021 gttacttctg cgcgctcgtt ttcttccagc ttcatacgaa tataatagat cgtttcttct
    13081 aattgaggga tcgtcatata ttctaatgca ttgactcgcc gacgtgtctt ttcgatttca
    13141 ctcgccatca gttgacaagt tttttcgatt tctgtcagtt ccaaaagttt tggaagcagg
    13201 gtagtaaacc gatcgattga ccgatccagt tcggcactgg aattcaaata cccgtattcc
    13261 aaaggtgtgt ctgtcagctg ttcatcatat tcaaaattca tcacaggtac ttttacactc
    13321 atgatatttt tgtctacgat agacaaatca acgttttccg ccggcaaaac aaataattct
    13381 tcgatgaaag gttccgtgat cgaagcattt gccaatacaa aatcagacat tgcttctgtc
    13441 atagactctt ccatttcttg acgcagctgg ttgttctttc gaatcaacag gatgaattga
    13501 cgcatcagtt catcttgctt atcttttaat aatttatgcc ctcttgtggc agttgtcaac
    13561 tgttttttca atcgagtcaa ttccatgcgg gtcggattca cattcaatcg tgccatcaga
    13621 actcacttcc cttctggcag atatttgtcc agcatgtcgt ctttgattcg ttttaattcg
    13681 gttcttggca acatcgatag cagttcccac cctagatcaa gtgtttcagt aatcgaacgg
    13741 ttcgtgtaga atccttgatt gacatattct ttttcaaacc gctcagcaaa cttcgcatag
    13801 atcttgtcta catcagataa agcagattca cctaaaacta cggctaattc ttttgcctgt
    13861 tttccttgtg cataggctgc aaaaagctga ttcatcgtag ctgcatggtc ttctcttgtc
    13921 tttccgggtc cagttccctt atcttttaac cgcgaaagag acgggagtac atcaattggt
    13981 ggctgaatcc cactcttgta aagctctcta gtcaagatga tctgtccttc tgtaatataa
    14041 ccagtcaagt cagggattgg atgagtttta tcgtcttctg gcattgttag aatcggaatt
    14101 tgagtaaccg atccttttag tccgcggatt cttcctgctc gttcgaataa agtagctaag
    14161 ttcgtgtaaa gatacccagg atatcctctt cttcctggaa cttctcgccg tgctgcagaa
    14221 atctctcgca atgcctctgc atagttggtc atgtctgtca tgataaccaa aacatgcatt
    14281 cccttttcat aagcaagata ttctgcagca gtcaaagcca tacgaggagt agcgatacgt
    14341 tcgattgcag ggtcgtttgc taaattcata aacatgacag aacggtcgat tgcgcccgtt
    14401 tgacgaaaat cttccatgaa aaattcagct tcttcaaaag tgattccaat agcagcaaag
    14461 actacggcga aatcatctga tgaatcgagt accgttgctt gtcgcgcgat ctgagcagct
    14521 aattctttat gaggaagacc agagccagaa aatactggta atttttgccc acgaactaat
    14581 gtattcaaat gatcgattgc agagatacct gtttggataa actcatctgg ataatcccga
    14641 gctactggat tgattacttc tccgttaata tccaaatgct tttcaggcag gatctctggt
    14701 ccgttatctt tcggtcgtcc caaaccatcg aatactcgac cgatcatgtc ttccgataca
    14761 cctagttcta aaggatggcc taaaaatcgt acagaagagt cacgtaaatt gataccactt
    14821 gttccttcga atatttggac cattgcttta tcttcttgga cttccaatac ttgtccacga
    14881 cgaatctcgc cattttgcat acggacttcg attaattctt catatttgac accagcaact
    14941 ttttcaaccg ccatcaatgg accgacgact tcaccgatcg tacgatattc tttaatcatt
    15001 gctcatgcct ccttctgaaa cgatcgtttg catcgtttgc ttgatttcac caataatttg
    15061 atctagtttt tctaattctg tttccgggat atatttgctt cgtccgatcc tttcacgaat
    15121 cgatacggta ccgtccatga tctcacttaa ataagcacct aacgacaacg cacggcgtcc
    15181 ttcttcacca aaggtcaaga tcatcttcaa cattttgaat tgtttctctc ttgaagtgaa
    15241 tgtatcgaca tcatcaaaag cattttgctg caaataatct tcacgaatgg attttgccac
    15301 ttctaatgtc agacggtcat tatctgaaag ggaatcaatc cctaccaaac gcacgatttc
    15361 attcagctgc tgttcttcct gcaaaatacg catgccctcg gtgaccatgg atgcccagtc
    15421 agcttgaagg atatgatcca tatacttccc tacttctgtt gaataaagag aatagctttg
    15481 tatccaatcg atcgaaggaa aatgtctttt ttgggctaaa ctggaatcaa gaccccagaa
    15541 tacttttacg acccgcaatg tattttgtgt gactggttcc gaaatatccc ctccagacgg
    15601 ggatacagca ctgattgcgg ttatacttcc ttcgcgacct tctgatccta atgcaatgac
    15661 tcttccagat cgttcatagt attccgcaag ccgtgaacca agataagctg gataaccttc
    15721 atcaccaggc atttcttcca aacgtccgct catctcacga agtgcttctg cccatcgtga
    15781 agtggagtct gccatgatag caacgtcata acccatgtca cggaaatatt ccgcaattgt
    15841 gattcccgta tagatagaag cttctcgagc tgctactggc atgtttgatg tattagcaat
    15901 caataccgta cgttccatca acgattctcc tgtattaggg tcaatcaatt cagggaattc
    15961 atttaaaaca tccgtcatct catttccacg ctcgccacat cccacataga caaccatgtc
    16021 cacatcggcc cattttgcaa tttgatgctg aacgactgtt ttccctgcac caaaaggacc
    16081 aggtacagct gctgctcctc cttttgtcac tgggaagaat gtatcaatca ctcgctgtcc
    16141 agtgatcatg ggtgcatccg ggtttaattt ttctttgatt ggccgactac gtcttactgg
    16201 ccatttttga agcatcgtca aatttttgtc accattttcg gtttcaatga cacatactgt
    16261 ttcatcaata gtgaatgaac ctttttcgat tgttttgatc gttcctttta tcccatttgg
    16321 caccatgatt ttatgtttta taacttttgt ttcttctacg atcccgataa catctccagc
    16381 actcaccgtt tctccggctt ctactgttgg ttcgaaccac cattttttct catggtccaa
    16441 tgcgggcaat tgaactccgc gccctaagaa attactttgt gtgatttcca taaaggtatc
    16501 taatggccgt tggattccgt caaacatttg tgaaatgatc cctggtccta attcaacaga
    16561 taaagcttca ccagtagagc gaaccggttc gcctggacca attccagaag tctcttcata
    16621 tacttgaata gacgccacat cgccacgcat ctcgataatt tctccgataa ctcctagatc
    16681 tcccactaga cacatgtctt ggatactggc atcagacatg ttctcagcca ttacaagagg
    16741 tccggagact tttatgattt ttccaatttg caaaatttct atctcctttt catactataa
    16801 gatattttga cctactgctt tttctacgtt tttttgaatt tcttccagcc ctatccctaa
    16861 tgatccttga tgattgggaa tcaatacgat agcaggtatc atttgttcct tgtaacgttc
    16921 gatcgtttct gggctcaatg ctgcacattg ctctgtgaca taaatcacgc catactcatt
    16981 ctttgccatt tcttcaattg cctgacgaac ggtttgcttg gttgtaccat aacgaacatc
    17041 aaagccaaac aatttgaatg gcaaaacaga atctttgtcg ccaactacac cgatcttatg
    17101 cgtcatagac ttgtctcacc cgctttctga ttgtttctga ttcgaaatgg cttcttttgc
    17161 cgataaccag taaacgaagg tttttgcttt ctacctcttt tgcgttcaaa aaggctagta
    17221 gtggcagtgg tccgaaagcc tgggtttgtg cttcttgata caatgaactt agataatcat
    17281 ctttcaactg ttcaagcttt acgagatcaa tatttccctc acggatgaca gggcgcagaa
    17341 aatcagcata atctgtctct aatagaaaat tcgtgtaatc ttccatatct ttatctacaa
    17401 agttcaaaaa tacttctttt tcgatacttc ccgagctgga aagtaccgtc gtcatgaacc
    17461 catatgttct tttctgcaat attcctcgag ccatcgttgt gatattggtc aagtcaataa
    17521 aagcaatgac ttctgtcagc aattcttgat atcctagctt atcggcaagc cgtcgctgct
    17581 ctgtcaaaaa ctgtcgatca taaatcacgt caattccctg aagaatggta gactcttcaa
    17641 aataatcacg tacttctcgt atactgtcca taatgctttc aggaagttca tttgaaactt
    17701 gcgtatgaat ggcatccttc aaggtttcta atgaataaaa tccatcgtcg atatacaaat
    17761 ggtccagatt ttgatttgtc atctcagctt ttgtcaaaac cttcagatta tggaaagtat
    17821 aacgcatcgt atagatccaa acgatttcag gctccggtgc tgattccttt aaccagcgaa
    17881 atagacggct ctgctccttt aaaagattct gttcgaagtc atattcatat ccgtcataaa
    17941 tatatggact gtaaatcgtg gatttcaata tttcaccaag tgcttcgaca gaatttgttt
    18001 gaatcatccg ttcaaatgtc tcattggaca aaagttcaag ctctcttccg cgaatcaagg
    18061 gatttagttc gtggtattcc atacactgat ccctccttat tcgaataatt gattggcaat
    18121 ctcaaaactc atcgttcctt ggatatcttg tacaaggctg ctgaaaagaa aattatactg
    18181 aactccttga tcgtttatca gaaaacccgc ttgatcagca acagtttcat cacttaaaac
    18241 catcataaag ggaagttcat tgttccattc atccaacaac gtctgagaaa gataggctgc
    18301 tgatttttct ccagcaatga atgctacttt tcctgtcaaa ggtaatgaat acaatgcatt
    18361 tttgataaac tggatttgtt cagattcatc ccaattttcc atttcagtta ccgcatctgc
    18421 aaacaatcgt cttaaaaatt cctgcttcgc attcaaattt tcttgtcgta cttctacttg
    18481 ctggcgattc cttagctgac ggtatttttt ttcgagtaat tcgatttgtt tttctttttg
    18541 tttttgatgt tctgtttcaa cttgcgtacg tttttgttca aagttttgat cgatcttcat
    18601 tcgctcttct tgttctaacg ccgctctttc ctgctctgct gcttcgttca tctgagagat
    18661 gattttttca atggcgttca tctgcttttc ctcctttatg cttaggcatt caacactaat
    18721 aggaaggaaa taacgaaacc taaaatcgcg tatgtttcaa ccatcgcagc aaaaatgatt
    18781 ccttttgtag catgttcagg ttttttcgct aaaatttgaa tacctgccgc tgcgactttt
    18841 ccttgggcaa tacctgaaaa caagcctgta aaagcaatcg gcagagaagc acctagaaag
    18901 ttcagtcctt gtacaactga catgtcattt cctaagttga taaaaatcaa aaaggcaata
    18961 acgaatccat acaaaccttg cgtgcctgga agcaattgca gaatcagagc ctgcccgaat
    19021 ttttcgggtt gacttgttgt caatgctgct gctgcctcac ctgtcattcc aacaccttta
    19081 gctgaaccga tccctgaaaa aatcgtcgct gttgccatcg ctaataccgc aaataccatt
    19141 ccaccatttt gactaattaa gtaatccatc attatataaa aatcctccaa ttatttattg
    19201 ttttttttct tgtgattgat gttgacgtat ttttccgccg ttttcagcgg atcaaaggca
    19261 cgtccgcctc ctgtataaaa cttcccaaaa aattcgacat actgcaatcg tgcgccatgg
    19321 acataggcac ttagcagtgt caaaaacata ttcagtgcgt gtaaagcgat gatcaaaagg
    19381 atccctacac tgaatcgagc agctggcggc atgaaagcaa ctagcatatt gaatgccgct
    19441 ccaatacttc cgcctgaaat acccaatgcc atcaaacgtg tataactgac taaatcaccg
    19501 atatagccgg tcagtccgta aagattatac gcacctttgg cagcaccttt gactttagac
    19561 ggcgtttgga taatcggaac gatcaagata cataaggcag caatgatcga tagcccagcg
    19621 ccaaggtaaa caaatgctgt attttttatc aacatggcac caaccaacgc aataacgatc
    19681 ccaattagga tcccttgcca ggcaaatcca tcactgacag cactcaagta atcttttctc
    19741 ctgatatttt cctttgctgc cacaaataat ccaaccaaaa tctgtatcag accgaaaatc
    19801 acggataaaa tcaaaatcgt attgacgtca tccgtcgtag ataggattgg gaaaggcaag
    19861 cggatgccaa acagttcttt tggtaatgac tgtccgaaaa atgaactgta gatcaatccc
    19921 cagatgatcg atggtatcga gagaatctca aagaatttta cgaaacgttt catcccgcgt
    19981 ggtagaacaa gtagtttttg agctagtatt gtcccaatga gcatcagcaa accataacca
    20041 acatctgcga ccatcatccc gaagaagaca agataaaatg gtgtcatcca aggtgttgga
    20101 tctacttctt catattttgg cagactgtac atttcagtca gcaattcaaa aggttcgaca
    20161 agcggatggt ttttcaattt agtagggact tcctgctgaa tctcttctga gtttggtgtt
    20221 tcgaaactga cgtatatatc ttcttctgat acggtttcgt ttaacacatg cagcaaattc
    20281 tgtttttctt ctgcatctac ccaaccttgc aaaacgatca gataagtcgc atggataaac
    20341 cgttctttta ttttttctcg ttctgcaacg gcaagtgtga cttcttctac ccattcaaat
    20401 tcttggatat agccactgca ctgacctaac gctgtcgtta tcttcttttg ctgctcgtga
    20461 acaatggata attgctgctt ggtctcttgc agtttttctt taggattttg ttcataagga
    20521 tacgtttctt tattgaaccc gtatttccca gcaatttctt ctataacagc aactgatttt
    20581 tttaaagcaa catacgaaag ataaacttgt tttggcgtat aatctatttc ttccatataa
    20641 acgtcatcaa gcttactcag ttcttccttg aaactttcaa aatttgctgc actcacagtc
    20701 cccatctcaa aaatggtcgt cttacttgca tacatacttg gagcaatatc cagctgttgc
    20761 caatgaagaa gccattcttc ctcttcttct aaacgatcac gttcttcagt tagttgttcc
    20821 cacttttctt ttaaatcaag gacttctttc aatttattta tgaaattttc ttcggaataa
    20881 ttggcttcca aatcttgtaa ggaaagttct tgacgtttca aatggagttt cttttgacgg
    20941 ctatcgccgt ggtgttgtat gaattggata gcttcttgga tgtctttcaa ccgattacct
    21001 aaagcgctta attttgcttc tttatcaata atcgtggtat ctggaaaata cttctccacc
    21061 cactggttgt ttgttctatt ttgatacaga tcccggattt caacgttttg gattccttgt
    21121 actgcttgta aaatcctctc ctgatttctt ttatctgaaa tgagggtcac tttttccatc
    21181 ttagtgacgg ccataagttt ctttcaccct ttcaatgatc gcaccgatcg cttgactctg
    21241 atgcttttga tattgatctt tcaaagttgc ttgcaccttg tctgcttctg ctttcaattt
    21301 cattttttct ttttctaatt cttgtatttc aaattgttct ttttcttcca ccaactgttt
    21361 tagttgttgt cgatagtttg tttggatcgt ttccaattcc tgctcttttt ctgttgcata
    21421 gatcttcagc tgctgccgca gtgtttgagc acgcttttca ttttcttctt ctgcttttcg
    21481 gatttgttcc aaagcttcta acacttgctt cacttccttt cgatttaaaa aagaggtaca
    21541 tgctttcttt tttcattgaa agtatgtacc tctaaagata acttagtata ggcaggcccc
    21601 ttcaataaaa tgtccttctc accccttgaa gaactagatc cttgaagctt acgcccaacc
    21661 tttttatttc tgcttacttt ttattataac aaattaagca atattttcaa ctatcgtcat
    21721 gaatttcaca cgaaatttct ctttacagat agtaacacag caagaacaga taagtatagg
    21781 ggcaagtctt acatagttta atttttttta aatccttgtt acaataagtc tactttaggg
    21841 ggaatacaaa tgaaaccaat catcggcatt gccggaaatc aactgattcg agcaacagat
    21901 actttccaag gaaatcaagt gagctataca ccgcaaggat tcgtggatgc agttttagat
    21961 gctcaaggat tgcctcttat tctgccagtc atgtctccag attcagctcc tcaactgatt
    22021 ggacaaatcg acaaacttat tcttgcaggt ggtcaagatg tcagtccaca actttacatg
    22081 gaagatcctc atccaaagct aacggaaaca aatattcaac gagaccaatt tgaacaggca
    22141 ctgatcttgg aagcattgaa acaaagaaaa ccaatttttg cagtctgccg gggactccaa
    22201 ctattgaatg tcgttttgga aggtacactt tatcaagatc tttcattata tccaaagtgg
    22261 tcagtaaaac atgaacaaca gcccactgcc ccgcaattta cgactcacga agtcaagatt
    22321 gtttcagaca gtttgttaag caaccttctc cccgatccat attttgtgaa ttcttaccat
    22381 catcaggcag tcaaagatct ttcaccttta ttaaaagcca tcgctttttc taacgatgga
    22441 ctcgttgaag cggttcaaag caaagatgat atgcataaaa tcctcggtgt tcaatggcat
    22501 ccggaactta cccaccgtgt acatccatct gaacagcgct tattcgattt ctttgtgaat
    22561 gaattttaat agactttctg agggggttgt gaaaaagctg tttagtttcg agtattaaga
    22621 aaaattttgt gaaaatggct tttcacattt ttgcataaat ttggcttaat accgagaaac
    22681 tggcttttga acaccgttta taccaagagg tcgtgagcct gccgttcaac tctgagtcac
    22741 aaggagcaat ttcaaaaaac agcttttcat gtttgttgaa tagtgtgact tgtgaccgag
    22801 gagttggcag aagaacaccg tttatccgga aaaagagact gcgacacgac ttttgtctca
    22861 gtctccagtc tatggaacaa tgttcactgg aattcttctc aatcgtcctt tcgatagtcc
    22921 aacagccttt tgagctgggt aatctgctgc tgcagttcca taccttttgt tgtatcacga
    22981 ttgagtttgc gtggtagttg ctgttcgatt acttttttca catttgtttg gtcggatttt
    23041 tttgcaaatt gttgttcaat aggcaaaaac ggataatgtg tcacgatttg gaaaccataa
    23101 gaattgcata atagtgaata accggcaatt cctgtcgttt tttgataagc tttggataaa
    23161 cctccgtcaa tgacaaatac ttttccattt gctttgatcg gtgactcccc tttttttact
    23221 tttactggcg tgtgcccatt aatgattgct gacccttctt cttttgtgtc gaattctgct
    23281 aaaatttttt cactgaacca ctcttcatct cgcaagtgat aataaggatt gcttttctcg
    23341 acgtgcgtat gaggctctgt gagaaaataa cgttcaaaag tcgccatttt actcttgccg
    23401 aataaaggcg aaaatggccc actccacgca taccaaatca aatcggttgc taaatcttct
    23461 tttgcagtca gatcttttgc gctttcagtt atctgttttt caaaaaagcc cagcagttct
    23521 tttccgcgat aagattggtc taattcaaat gctaagagct gtcccttctc gtctacaggt
    23581 atacagccat gaaacagcac atgctgattg ttcgtgagat acattccccc tttttcgatc
    23641 aaaaacgtca tatgtttttg cattctcaaa gagtgctgga atgaatacat caaactatca
    23701 atcacttttt gttcctcttc caagaatttt tttggatcat ctggctggat cgtttgaaaa
    23761 caagttcctt tcaactcata gagctgacct tctaaatcaa tcgttgatgc ttcatagtcg
    23821 attttttcca gcaatttacg atcgtccatt ttaaattcag gtcgacgatc caataactga
    23881 tgttctgatt tgaattgaag gatagaaagt gcctgatgga ttttttctaa ttcttcttgc
    23941 tctctttcgg atagattttt actgttttta ggcgcaaata ctggattctt ctgataagtt
    24001 tgatgagcaa aagaaaacaa tggacgtaaa ttcaacccat attctttctc taattcaaat
    24061 aaataattat agcgtgctgc aatccgtaaa agtgtcagta aacatgcctc agagccgcaa
    24121 tacgcaccaa tccacaaaat atcatgattt ccccattgga tatctacaga agaaaaatcc
    24181 atgattcgat ccatcacttt ggctgcttga gttcctcggt caaaaatatc tccaacgata
    24241 tgcaaatgat cgatgacaga tttttggatc gtctgtgcaa gtttcgttaa aaatttttct
    24301 tcttccttca tcaaaacaag ttgttcaatg atttttttta catagtcttt ttttccattg
    24361 atacggtcat cgatatacaa gagttcctca atgatatagc tatattcttt cggcaatcct
    24421 tttcgaactt ttgaccgggt atatttgact gtcgtaaacc gtaaaagatc gatcaaatga
    24481 tggatcagct gcgatttatc ttgttctttg taccaatcag tcgttaatgc atattctgga
    24541 taagccgtaa aaatagtgaa ttggctgata tccgtttccg tcatttgttc agaaaaaagg
    24601 tctttgatct tttctttaag atttcctgaa ccgatacgca gaatatgatc aaaagcagga
    24661 aattcgccat gtatatcact caaaaataac tctgttcctt ttggaagctg caaaattgct
    24721 tcgagattga tgatttccgt gatgacatcc tccgttgagg ggaatttttc tgaaagtaaa
    24781 tctaaataac ggtccattaa aacgcctcca aaaattggta tactcaatat tataaagttg
    24841 ttatacacta ttttcaatga atatatatcc aatatagtaa aataaataaa ataggtctat
    24901 acaaaaagaa gctgggaaca atagatgtcc agcttccttc tgtattttag gattgtttta
    24961 tgcttttttt cgttcattcc tcataattga aatcgattgt ttcaatgaac tccataatcc
    25021 gccttcgcta taaacgagta cattcgattt gtacatgttt gcagacaaga tcatcaataa
    25081 gaatgttacg gctacaagta ccaacaagga aatcaatgct ccacccatac cgactgtctc
    25141 atttgctaag cgaatcggca taatatatga agataagaat ggaatatacg aagtgatccg
    25201 aataacgata ttgtttggat ctgaagctcc tagtatcaat ccaagcatgt atccgcctag
    25261 agatagataa gtcactggca aaattgcttt tgctgtatct tctgctttgt tgaccaaaga
    25321 gccacataaa gctgctaaaa cagaaaaaat caaaatgcca aagatcatga atagaagaga
    25381 ataccacaag aatggtccaa tcaagttatc caatgagata ccgtctaata tatttttgac
    25441 catttccata tctttgaatt gactgtatcc tataccaaaa ataataccgt ataatgccat
    25501 ttgcgttaat gcaacaagta aaacacctgt taattttccg taaaaatgct tttgtgcagt
    25561 cgtactggac aggatcactt ccatgatccg cgtgcctttt tcagaagcga tctcttgtgc
    25621 aatgatctgc gcatacgtca aaataataat gaacaagaca atcgttgcta cataacttac
    25681 gacgtattgg actgtcgagt tatcttctcc gactgtcatt tttccttttg aatcaaaatt
    25741 gactttttgt cgagtcaaac ttgcttgttg gctcaagcta gctacttctt ctggtgaaat
    25801 gcctaattga ctcgctcgaa gcatcgattg caagccagtc agttgttgtt gtatcagtag
    25861 ttgtgtactt tgtcctaatg aattttcgct ataaagcatc ccatttatct tatcattctc
    25921 agttgagact actaaatacg catcgatttt ttcttccgaa agctcttttt gtgctttttc
    25981 ttcagaatca actgctttga actcaaaatc atctgttttg acttggctca tttgctgact
    26041 gatttgctca ttatcagcca atacgccgat tttattgaca tcactatttt gttgagcaaa
    26101 gtttcctgct acataaatga tacccagcat gataaaaggg actaatatca tgatcaagaa
    26161 agaaatcgac ttaacatttt ttaaatagac atctttggta ataatccaaa acttacgcat
    26221 cgatttcacc tgctttcaat ttgaaaatct cttccaaagt tggcggttgc tggttaaaca
    26281 taggaatgta gccgaactga gtcgcacgag taaagatttc tttcccagct tcaggatctt
    26341 ctaaggtaat ctctaacgta ttgtcttcat gaaggatcac ttttttcacg ccttcgattt
    26401 cttctacttc ctgttggctt aaaccagatt ccaagaataa cttcgtacgg ccaaatgatt
    26461 cacgaatctc atgtactttt ccattcaaaa ccatttttcc gtttcgcaac atgatcaaat
    26521 gatcgcagat tttttctaca ttatccatat tgtggctaga aaaaatgaca catgaaccat
    26581 gttttttcaa ttccaatatt ccatctttta gcaattcagc atttaccgga tctaacccgc
    26641 tgaatggctc atccaaaatg atcaatttag gttcatggat taacgtggcg atcagctgga
    26701 ctttttgctg atttccttta gacaaagatt ttactttatc cgtctttttc ccttttacct
    26761 gaaatttttc catccaaaag tcgatttttg gttcaatctc ttttcttgat ttccctctaa
    26821 gttctgcaaa ataaagcagt tggtcttgaa tcgttacttt cggataaagt ccccgttcct
    26881 ccggaagata accgatgaca tcataatctt tctccccaag atgatggcca ttccataaca
    26941 cttctccttg gtcttgtgtc aaaaaatcca agatcaaacg aaaagtcgtt gtcttcccag
    27001 ccccgttttg gccaattagc cccatgattt ttccatcggg gatttggaaa gagacatgat
    27061 cgacagctgt gtagttccca aaagttttaa caagatcctt gacttctaac atttcttcac
    27121 tccttcttca agaaatcaca tatatcctta gacaccagac gtaagcgatt tattatttac
    27181 caacaaaacg taaacgctct ttttgttgta cataaaatga taggacactt tactttcttt
    27241 gtaaagtgcc ctttcctcat tcctgatgta atttatcaaa tacgttttgt gcgacatttt
    27301 tcggcagtcc gatttcttgt aattcttctg tcgtggctgc tgtgatattt ttcaacgatt
    27361 tgaactcttt aagcagcatt ttttttcgtt ttggtcctaa cccttcaatt tcatctaatc
    27421 gggaagcaaa actgttttta ctgcgtagct gccgatggaa agtgattgcg aatcgatgga
    27481 cttcatcttg gattcgctgg agtaagaaaa actctggtga atttcgctca agcggtacta
    27541 cagccaaatc tgtaccgaat agcaactcat ttgttttatg tttatcgttt tttaccatgc
    27601 cagcaatagg aatatcgatt cctaattgat tttctaagac atcttttgcc acatctactt
    27661 gtccttttcc tccatcgatc aagatcaaat caggtaaagg caacccttcg cgaatcactc
    27721 gcgaatatct gcgatagatg acttctctca ttgatgcata atcatccggt ccgttgactg
    27781 tttttatttt atatttccga tattcttttc ttgccggttt tccatcaatg aatacgacca
    27841 tcgcagccac aggattcgtc cccatgatat tagagttatc aaaagactcg atacgtattg
    27901 gggtcgggat attcatcgcg tttcctaaac gttcaactgc tccgatcgtc cgttcctgtt
    27961 ttctggcaat cagatcaaac cgttcattca aagcaactga ggcattctta ctcgccaatt
    28021 caactaattt tttcttttct cctcgttttg gttgcagcac tttcgtagct aacaaagctt
    28081 ctacactggg cttgtcgatc gtatcaggaa tcaagacttc tttaggaatg aaatgctcat
    28141 tttcctgata aaactgaccg aggtaagtca agaaatcttc ttctgcttcg ttatagaaag
    28201 gaaacattga aacatctcgt tcaattagct ttccttgtct tacgaaaaac acttggacac
    28261 acatccatcc tttatcaatc gcataaccaa atacatctcg atccagtaaa tcagtatttg
    28321 tcattttttg gcgagtcatg attgtctcaa tggcacggat ctggtctcgg tattctgcag
    28381 ctttttcaaa ctccatgttt tcagcagctt tttccatttt ctgatggatc tctgactcga
    28441 ttttttcgtg tcctccgttt aaaaagtttt tcacttcatc aacgattttc gtatagactt
    28501 tcggatctac gtcgaaataa taaggacaca ggcattgtcc caaatgatag taaagacaag
    28561 gctccttcgt ctgactaggt ttgcattttc tcagaggaaa taatcgatcg aggatcttct
    28621 ttgtctcatt cgccgcaccg acatcgggat atggtccaaa atacagtgct ttgtctttta
    28681 gtaccttacg agtaatcacc aaacggggat atttttcatt cgttatctta aggaaaggat
    28741 aggttttatc atcctttaac ataatgttgt atttaggatc atttttcttt atcagattga
    28801 tctctaagag caatgcttcg atattcgatt ctgtaacgat gtattcaaag tcttcgattt
    28861 cactaacaag ccgttccgtt ttcgtattat ggctaccagt aaaatatgag cggacacgat
    28921 tttttaatat tttggctttg ccgacataaa tgatcgttcc atttttatct ttcatcaagt
    28981 aacagccggg ctgatcagga agtaaagcta atttgttttt gattcgttcg ttcatctggt
    29041 actccccttc atattcaatt aaagttatta tagcatgtct gtcaaaaaaa caatccagcc
    29101 tgacaacgta attatactca aaaaatatta atttgaataa ccttaactca accgcaaaaa
    29161 aaccgaggac ggaactggat tcagtcccac cctcagctta tttttgctgt aagtttttat
    29221 aaatattgat cgatcatttg acgtagttgt tcttttgaat gaacaccaac agctttttct
    29281 actacttgac catctttttt caacattaat gttggaatgc tcatgatacc gaattgttga
    29341 ggagtttctg gattttcatc cacatccatt ttagcaattc tgaattcttc ttcatcatat
    29401 tcttgttcca actgatccaa aatcggtgct tgcatacgac atggaccaca ccaagttgcc
    29461 caaaaatcaa tcaatacaag tcctttatct gtttcttcat taaatgtctt atctgtaatt
    29521 acttgtgaca tatcaaagac ctccattttt aaaatctatg actagtatag catttctata
    29581 cttggatagc gaaccatctg cttaccttta gtaagcttta cttaaattta acaattgtcg
    29641 caccatttcc gccttggttt gccggtgcaa actcaaagct tttgacgctc cgatggtttt
    29701 taagataatc agtaattccc ttgcgaagtg cgcctgttcc ttttccgtgg acaatagtca
    29761 cttgaggata accagctaga atggcagaat ccaaatattg atctacctca cttagcgctt
    29821 cttcgtatcg ttttcctcga aggtccaatt gattcggcac gtgactacta gattcagatc
    29881 gtacagcatg gataactcgt tgtgtcggct ctttttgagg agcaacaggc gtcagctcgt
    29941 cttcggacac attcattttt aatataccga tttctacttg ccactgattc ccgtttttac
    30001 gtaaaagcgt ccctctttgg ccgtaagtcg taaccaacac ttcgtctccc ggtttcaacg
    30061 ttttttgttc tttcgccttc ttcaatactt tatttttctt caaagtttct tcttgatgta
    30121 gatttgctaa ttgggtcttt gcatcgatca actgatgctc tttcacattt ccttgcccaa
    30181 tctgctgttg cattttacga atatcagcaa tgattttttc tgctttttct tccgcctctg
    30241 acacgacttc atttgctttt ttctttgctt tttccatttc tttttcacgt tcttcaaaga
    30301 aatagctgta agcttctttc aaatcatcgt gaagttcttg tgcctcagaa acaaaatgac
    30361 gcatttccag atattcggtc tctgccattt tccggcgatt ctctaaatct gtgatcattt
    30421 cgtttaaatc ttggctctca tcattcatca actgcttcgc ttcatcaata acttctgtat
    30481 caagacctaa tcggctagag atttcaaacg cattgcttcg tccaggaacg ccaatcagca
    30541 aacgatacgt tggacttaat gtatccacat caaactccat gctggcatta atcgtatttg
    30601 cccgattata tccataaact ttcaattcag gataatgcgt tgttgccatc acataagcag
    30661 actttttacc aagatcatct aagattgcga ttgctagagc agcaccttct tgcggatctg
    30721 ttcctgcacc gagctcgtca aataatacca gacttttttc attgactttt gataaaatat
    30781 ctacagtgtt cgtcatatga gaagaaaagg tcgatagact ttgctcaatc gactgttcgt
    30841 ctcctatatc cgcaaatact tcctcaaaaa taccgatttg actttcttca cctgcaggaa
    30901 tcggtaatcc tgcttgcccc atcagttgta acagacctaa agtcttcaac gtgatcgttt
    30961 tcccacctgt gttaggtcct gtaatgacga tggcttgata gtcttttccg attgtgatgt
    31021 cattagaaac tactttttcc tgatcgatca gtggatgtct tgcttgtttc aagacgacat
    31081 gattgtcttc actgattccc ggcacgatgg cttttacttc tttaccaaat cgtgcttttg
    31141 cattcatcag atccatttta ccaatcacat aagtattgtg gatgatttct tgacgatggg
    31201 gaacaagttc agcagaaagt tcacttaaaa tacgttgaat ctcatttcgt tcagcgattt
    31261 ggtattgacg caaacgatta ttcaaatcca ccacttgttt tggttcaata aataaagtct
    31321 gacctgaagc actttgatcg tggactacac cgccaaatac accgcggtat tcttgtttga
    31381 ctgggataac gtagcggtca tttcgcatgg tgatgatcgc atcacttaaa tactttgcat
    31441 ttttcccacg gacgatccca tctaactgtt cacgaacagc ttgttcactt cgccgaatgt
    31501 tctgtcttat gctctttaac tcaggagaag cgtcatcagt cacgcgtccg tcttcatcga
    31561 ttgcttcctt taaacggcgg ctcaaaacag ggatcgtgac taactgatct gcccacatat
    31621 acaaacgtgc aaattcgatt tcactgtcag aaagatcatc aatgaaacga ttcaattcgc
    31681 ttgtcgtaga caatactctg gaaacttgtg caagctccac tccattcaag tctgctccga
    31741 tctcaatccg tttcatatgg ggacggatat tttcaatttt aggtataggg atcccgcctc
    31801 gcagacgttg cactttcaat ccatcctcag tttcttgaag ccagtttgtg atcgtttgtt
    31861 tctcactcac tggtaccaat tctgccagtt cttcttttcc ttgtgcagtc actacaaatt
    31921 gtctgaccat ctgtttgact ttttcaaatt ccaatgtttc aaggattcgg ttattcattt
    31981 tatcacctta tctttcacta tgaaaaaaga gctgtgccgg acatacgcta cgcagccttc
    32041 ttaaataaac tactctgtac aaaaaacgaa atattttcca gcactatttt ccttaattca
    32101 aaatattcgt tacccaaagc tcatacatct tgttggtaag aaatggcgtt ctctcaacga
    32161 taaaacgagc gaaactatgc tcgccgaatt gattttggac cacatctaat ggaacaaagg
    32221 caagtaactg caaaatcaaa aatatagtaa cgtaagccat gattagtgac aggatgcctc
    32281 ctgcaatcca gtctacctgt ctcaagatcg gcacatacgt caatccatgg acaaaaaccc
    32341 ccacaaatcg ggtaagcagc cagccaatta gcaaaataat cagaaaagca gttcctgcat
    32401 aaaaagcttc atctaggtga aaggcaaata cctgatcaaa aaatgctaac tttgatgttg
    32461 gggtgacagc tgggtatgga atgtataatt ccaaatgact tgctaatggt ttgtaaaaat
    32521 gctgggcagc aataaatgac aatacatatc caatcgcgaa tatgatttgc aaagcaaacc
    32581 cgcgacgtgc tccagaaaaa aacgcaatta gcaataaaaa taaaatcagc aaactcagca
    32641 tgctacgttc ctttctcttc taactttttt aaatttttct tattttgata aaaggatctt
    32701 aattagaaga tttttgttta atttgtcctt ttcgtttctc gtttaaaatc tgttgtgctt
    32761 ccacatgatt tttaatggta tgatctgctt gaccattttc tttcaatact tcccgagctt
    32821 cgttctcgat tgcttcaatg cgtttcacac gattttcaag ctctgtaaat ttgatcattt
    32881 ttttctttaa ttctgctgtt tcttcttcca gctccaatat tctttcttgt ttcttcaatt
    32941 gatccgaaag cgcattgaca gccatcaaga ttgctgcttg ttcattatcc atttgtggtg
    33001 ataattgttt caattctgct aactgttcat tgatcagctt cgttacgata tccatatgat
    33061 gcttggtttc ccgtccgata atagtatatg tttggttggc aatcaccgct ttgtagcgtg
    33121 ttttttcgtg cgccatacga atcatttcct cctatttgat gaaagtttta tttagtgtac
    33181 catgaagttg gttctttcac cgttctccac aaatattttt cacatactta actattatat
    33241 gataaacttt aaaaaaatgc tatgtctcgc aatctcttag aaaacgaaaa gtcgtgagtt
    33301 gcggtatagt tttatgtata aaaacgagga gaattttatg agcaacgtca ttatcaaagc
    33361 aacaaacgac caacttagtc aaatgaaagc atactatcgc tcttatttgt taaataaaca
    33421 gattccttat actagctttg ctgcaaaaaa agacgggacg accattaccg cttatacatc
    33481 cggaaaagtg atgtttcaag gtacgaatgc agcaatagaa gctgataaat ggggggaggc
    33541 acaggataaa caagccaagc cagcaaaaac agcctcttct ttgccaaaaa atatcagtca
    33601 attatccgtt ttaggtagtg atgaggtcgg aaatggcagc tatttcggtc cgctaacagt
    33661 atgtgctgct tatgtgaaac gtgatcagct tgcagaatta cgtaaacttg gtgttagaga
    33721 ttcaaaagag ttaaaagata gccaaatcat ccagcttgct gacatcttaa aaaaaaccat
    33781 cccctataaa ctgcttgtct tatctccaga aaaatacaat gagatccaac caaaatacaa
    33841 tgccgttcgg atgaaagtcg ctttgcacaa tcaagcgatc catttgctgc taaaaaaaat
    33901 cgagccagaa aaaccagaag cgattttgat cgatcagttt acgccggaag caaattttaa
    33961 aaaatatgcg cgtttagaaa aaaatcaatt acaagaaaaa ctgtacttcg ttactaaagg
    34021 agaacaatat catttagctg ttgctgctgc ttctatcatc agtcgtgcca gctttttgga
    34081 agagttagac aaagcatcag ctgaagctgg aatcaccctt ccgtcaggag ctggaacgaa
    34141 atctgaccaa gtagcggcaa aactattgga gaaaggcggc atgcctatgc ttgaaaaata
    34201 tgccaaactt cattttgcca atacagaaaa agctttgaag ctactaaaaa aataatggaa
    34261 ctgtgacaaa agtcatgtca cagtcccttg ttccgaataa acggtgttca atcatctgat
    34321 cctcggtatt agctcaacaa acggcaaaat atgaggaact atttttccgt ttgtttctct
    34381 aatactcaga acaaaacgtt gatttcacaa cctttttctt aaacggtgtt ctcatgccaa
    34441 ctcctcggtc acaagtcaca atagtcatca aacatgagaa gctgtttttt gaaattgctc
    34501 cttgtgactc agagttgaac ggcaggctca cgacctcttc cttaaacggt gtttaaaagc
    34561 ttgcatctgc gataataagc ccggccaaac gaaaaatatg aggagctatt tttgtttggc
    34621 tgggcttatt tattactgaa aataagtggt caatgcttgt gtcaaacttg cagcaatctg
    34681 ctgctgataa ctgtctgtta ctaattcctt taaatcacta tcattattca tataacccat
    34741 ctcgattaaa atagaaggtt gaagattttc tcgaagaact tgatagttcc cagtggagat
    34801 tcctcttgaa tccagaggca gatcagtgaa ggagtcagca attgtctgtg ctaatgtttc
    34861 ctcttgtcca tagtaataat atgtcgtgat tccagttgct tcattcgcat attccgtaga
    34921 gtctgcgtgt aaactgataa agacatctgc ctttttttct tcactgtagt cgcatatatc
    34981 tccaagctgt actaattcat ctgtagtatg ggtcaaataa accgttgctc cagcatcctc
    35041 tagcgccttt tttactttta tggctgtact taatgttata tctttttctt ctgtttgttc
    35101 atcattgctt aatgccccag tatcatttcc gccatgccca ggatctaata caatcactgc
    35161 atcagatagc tcttccggtt ttgtttgtat attctttgtg actttggttc catcttcgag
    35221 ggctaaatat ccagtatagc catcatttgt cttgatctga taagcatttt ttgtttcaga
    35281 aagaaactcc gccagctctc cgccgtttat agttgcaagt ggggtagtta gcgagtcatc
    35341 tgtatatagt gtacggtcat tttttccgat tttgattaat gtctcttgtt ctgtatcatc
    35401 aaatgattcc tttgtctttg taaccgtact gttcgtactg ctgaccgttt gtccaactat
    35461 ctttttttga ccaaaaacat ctatttgaaa acagataata atgataatga ttgcaaatac
    35521 aaaagctcca attatttttt tcattcttga ctctcacctc gtagatccag actaagggcc
    35581 aaaacttaaa atcagcttaa gtaagcaaaa aaggggctgt aaaagatata accgtagaaa
    35641 ataacattac tgctaaaatg atttttttca tttttggcat atcctgaaat ctccttttga
    35701 ctattcgtgg tgattcatct acccaataaa tagtttcctt cattctacaa acaattaatt
    35761 tcttcgttat taaattaaaa cacttcctgg aacaccgaca taataaataa aaatataccc
    35821 tgataatcat gagagaataa caaatttgta tttatgaaaa actacctata taaagaagca
    35881 agatataacg atcttcgtca tatcttgctt cttcacctaa ctattttctc cctatataac
    35941 agctttacgc ttctcctaat acaccattca aatataaatc gatcaattgc gccacattta
    36001 gcggttcttc cacaggtctt ttcgaccgag tgatgtaagg tgctaacact aagaaaaaat
    36061 gccttgctgc gatttctttt gaaatcccat ttcttagcac agattggttt gctgaaaaga
    36121 tttcttcaaa aggttcacga taatttttct tccatagaaa gaaaagatga tctcttgttt
    36181 cctttgaaag attgctttca agatcgtgaa gcatcagaaa caaatcgacc agatgtgtct
    36241 caatcaaaaa ctgcgccatt tttgtcaagg ttacttgaaa tcccgtttcg cttgtttgaa
    36301 cgatttctct caaagctttt ccaacatctt ttaagtggtt ttctaaaact gccgtatata
    36361 gtttttcttt atcaccgaaa taatgataga gattgggctg ggtgatccca actttttgtg
    36421 cgatttctct tgttgaagtg ccgagatatc ccttggacat aaacaagtca gtcgcttctt
    36481 tcaaaatttt ttgctgtgta tctttgttgt atcgatggac catttttcca cctgcttttt
    36541 ggttattctt tttctttcaa tacaccatct tccatcataa atattctatc gcatttgtca
    36601 atcagccgtg tatcgtgagt aaccatgatc gttgctttat ttttgtcttt tgattctttt
    36661 gccaagatat cgactacttc tcgtgccttt tctgaatcca aactagcagt tggttcatct
    36721 gctagaataa tggacggatc attgtacaat gcacgagcga ttgcgaccct ttgccgttct
    36781 ccaccagata gttcttctgg atacttgttg atcaacttat ccacgccaag ctgctcaaat
    36841 aattcgtttg cttctttttg acgatgttca tgtttaatct tatctactaa taataactgc
    36901 ttttttactg tcagaaaagg aaccagattg gaagcttgca aaataaagcc aatttcttta
    36961 aaacgtagtt taacgcgttc gctttctttt tgattactga attcttgatc attgataaat
    37021 acagagccac tgctaggcgt ctgcaatccg cctgccaaag tcaaaaaagt acttttacct
    37081 gaaccagaag gaccgatgat tgcaacaaat tcccctttat cgatactcat ggttgtttct
    37141 ttcaatgctt taactacttg gtcgccatct tggaaacttt tttctacttc tttaaattct
    37201 attgctttca tgttcttcct ccttcttatc caattgcctt caacggatcg atttttacga
    37261 ttgtccgaac agaaaatagt gcgcctaaca cagctactac taacatcaac aagctaatga
    37321 cgccaaaaaa cagccaattg ctttggaatg gaaccgcatc aggtagaaca agggatgttc
    37381 ccactgttcc taatagacca agaagaatac caacaaatga taaaatgaat gtttgtgcca
    37441 ctacagaacg cgcaataaat cctcctgtga tcccttgtgc tttcattaca ccaaagatat
    37501 taatcttttg catcgtcagt acataaatga aaatcccgat cacaatagcc gcaataacga
    37561 tcaaaaatcc gatcataaat ccaaaagtca atacttgcgc attatatcca ggtaattcat
    37621 tgatgaattt agaaattttg atctgttcta aatcttcagg taaattactg attttacctc
    37681 tgacaactat tgcgttaatc cgtgcatttt cacttgtatc ttctttttcg aagcggattt
    37741 cttggtaagc attgatggtt gtatagagaa ctggtgagac attgaatttg gcatgatccg
    37801 taaagccagt tagtttaaac gtcttgtcac taccagataa cttaactgta tctcctatgg
    37861 ctagaccata ttcttctttc aaactaatat cgcctactgc ctcatcatcg ttatcaaaag
    37921 cttttccttc aacaagattg ggcatgatga attgattttt atcgataccg aagaagctaa
    37981 cattgatttt tccttcttct gtactgtctt tactagtcac gactccaggt gtttgggcaa
    38041 gatacgccac tttcccacct tcgacttctt ctgctatctt cttagtaatc atggacatcc
    38101 ctagatttga atttgcatct ttcgaaagca caatcgaatc tgcctcccac ttgtcgactg
    38161 ctgttcgatt atcttgagct aagccataag ctaacccagt caaaaaaaat accaggtagg
    38221 cgatcaaaaa catcacccct gcaactaacg cataacgtaa ctttgaatgc ataatttcat
    38281 ttaatgctaa aaacatttaa ctcctcctcc tgaaataatc attttataca acaattttat
    38341 cacttgataa atttttggcg aatattatgc tcaaaaaatt cttccgctat ttcattatat
    38401 gaatttttta ttctcgattg attaatattt attatatccc cacacaataa aagaccgtga
    38461 tatttctcac agtcttttat ctactctatt gctatttgct ctcttagcta gtactttaaa
    38521 agctaactca ttgaggtagt gaaaacgaga ggtgtattca gacagaaatc caaaatcctc
    38581 aactgctagc tgtggaatcg tagttttgtg tttcacgata tccgcaagca ggttcaaatc
    38641 tgataataag aattcttggc ttatcagctg tccgccaatt atttctaatg tatccggatg
    38701 gtagatcagc tttgcattta ctgttttgtt ttcttcgtcg tattgtggaa atagatcaaa
    38761 ttctcctgaa cacgaaccgg tattttgttc caagaatggc gcttcatctt ctgtcagccc
    38821 tacagttcct aaaaagtagt ctataatgac tgctgctgtt atcttttgtc tgaggtcgta
    38881 agcggttggc tgaccactca aagttagcgc tactgctctt gccatatgta cagctcgagt
    38941 aactaaaggt aaaaagagat gccgtttatt tttgtcaaaa ctgactggga cgatatctcc
    39001 aatcgcatag atgtccggat cacttgtctg cagatattca ttgactatca cagtctcatc
    39061 ctcatacaaa gccacttttt cttttaacaa tgtcgtatta ggacgagttt gggcagaaaa
    39121 aatgaccata tctgccttta ttgtttgaga cagaagttgt acggatacta ctttctcttc
    39181 tgattttttc caatcgatca agaattcatt tggataaaaa tttatttgct tagtttgcag
    39241 ctgattttga aaactgttga tcatatcctt atcgaaatat cttgataaaa cattcggcat
    39301 ataatcaact agatgaataa tgtatccttt atttctcaaa gcatctgcta attccaatcc
    39361 aatgtaacca gcaccgaaga tcactacttc ttttgcttct tttaaagcgg caagtacttg
    39421 cttagattgc actagatttt tataggtgta gacattttca gcttcaattt gtttatacaa
    39481 ggtgacagga gaggaacctg tcgctacgat taatttatca taggttatgg tctcgttttt
    39541 tccttctttg gatgcgagga tgagctgatg tttgtctgga tcaagttcag ttactctcca
    39601 ttcggtgatc agttttgccc cactttcttg aagagtccgc atgttatggg caacttcagc
    39661 taaactacgt atctttcctt ttaaataaag gttgattcca tttgaaacat agcctagtcc
    39721 atctttatga tcttcatcga tcagtaaaac ttctgctttc ggttgaagtt ttcttagatt
    39781 tagggcagct gtgatgcctt catgggaagc accaatgatc acgattttca tgttttattc
    39841 atccttaaat tcaatttttc taaataacat tcttttaaaa attggttcaa ataggggaaa
    39901 tcataattat attcgttgct agtgaataca aaaactttag cggacttctg tgacgggtac
    39961 tctttcaatt ggctagtcaa aatgatatca tactgctttt ctttctcgta ttcgactaaa
    40021 tcatatttga tcgtattcag caattgttcc tggatgattt ctttcacgat atccgccatt
    40081 agcctttcat aaggaagatc ataagcaatt tgcagacgta attctaactg cttgatcagc
    40141 gtccgtaaaa tagatgcata gcgagcaaat aattcaaagc gggcattttc ctcgtctact
    40201 tcagtaaaat caacaatagc aaatgtttgt ctgaccaatc tttcacataa aaccaggaat
    40261 tgtttatctt ctacttcagt taaccgctgt tttaatcctt cttggccaaa aatattcatc
    40321 catcctctaa aataggcaaa atgagcgtga ttttgcatca ctgtcaacgc aatcttttgc
    40381 gaaatctctt ctggaaaaac ataaaaagag aaatattctt ctatcgattg tttaaacgtt
    40441 cgattcaatt gagctactac gtcgtctttg tatttttcgc ttatcaaaaa ctcctggaca
    40501 tgcgagttat gtgtatctaa tgtaaagtta ctgatcatga aaagataaaa aaccaacgtt
    40561 tcattttgat tccaaggaaa ggcatattga aagaagtaac gggtcaaaaa tgtatggagg
    40621 tccaataaaa attgtgtcgt ttgaaacaat ccaacaggaa gattgctata atctggtttg
    40681 gattttttcg tacagcgcat tcgcttcttc ataatggaaa gccatatttc aaatttcaat
    40741 cgtccttctt ctgtaatagc aaaactaaac tctttttgca gcagatctaa aaaagtgttt
    40801 cctgataaat cactgtattc ttttttgttt tcaagatagg gacgtccaaa ccaaaataat
    40861 tggaaataaa aataacgaat ttgactttct ggaccggtca gccgcccgct ttttattttc
    40921 agatgaaact catttaaaga atcatttaat tccttcactc tgcgagacaa agtagccgaa
    40981 ctgatattaa gttccatgac aagtttctgc cgatcaaatg agccattttc caacagataa
    41041 agaagtatct gatattttgt agaatagcgc aagtaacaat gataataaac atcgactgct
    41101 gctatatttc catgtctgat taataaaata ttcccttctt ggataacaat ttccaattgt
    41161 ttgatatttt ccaagttagc ttgtaaataa aacagatctt ctttcaaggt agcccgatca
    41221 actgataagc gggtaagtac gttattaacg gaaacctctc ctttttcctc taataaaagt
    41281 tggaaaagtt tgatttgccg ttgttcattt ttttcaagca aactgaaaag ttccaagtcc
    41341 actccttcaa gcatttctga ttttaacagc agaagtttcc ttctcatcct tgaaaaagag
    41401 gatctgtgac agttatcaca gatccataca aattctaatc acttagctgg ttggcccagc
    41461 tgtcagttcc catgtgacca tgccttgata cgttgcgcca ggttgagcat tcgtactgct
    41521 atttacctct aagagtaaac catcggtatc gggaaagtca acgagaacct ctcctttagc
    41581 tgttccatca ctctcataaa tcaacgtgtt ttgaccttgc tgaatcaatt gctttgatcc
    41641 agaatgattg aagtataatt ttgttccgct taattcttga ccttgatcat tcttaaataa
    41701 agaagtcaat gtacctgtca gttgccaagg agacgtgctt ggaagccgag tatcccgcac
    41761 atcaaaagaa aaatcgcctt ttgattcata ataacttgtc ttcaacggtt tggggagatc
    41821 gttaccaaat gtaaaatcat ctggtacatt aactaatgtt aattcttgtt tggggacaag
    41881 aattgtttta gcagatgttt ggacaactgg gttaggaagc ttagcaccat ctgctaatgt
    41941 aatattgctg gaaagtacag ctgcctttgt cagtatgctg acggattgta aagaagtatc
    42001 tacagtattt aattgatagt tgtaagtaag atgaatggta tctcctattt tgctcaatag
    42061 atctgctggg acagaaactc cttgttgaat gccggtatct gcgatagttg taccatttaa
    42121 ttttaaggaa ccattgatat aagtagtatt ttcaggaagt gagatcgtga tttttttgtc
    42181 ggttatcgca tccccagatt ttgttaacgt gaatgtcaca ttttcttgaa tcgtatctcc
    42241 tgatagagca gacaggggat ctcctgtctc aggttgtctg ctaaggtttt ttagctgact
    42301 atctgcactc acagatggaa aattagccac tgttatttga ggaagagtgg tgattccagc
    42361 ttgttcagac tgccatttgt acgcaaaaga cggatacatg ttagtaagta catcgtccac
    42421 caagcgataa tcaaaataat attgccctga agccaatgca ggtagtgtag aagtagctgt
    42481 atttacaccc ccgttatttg attggatcgt ttggaaaagt tgatctgtcc atcctgtcgc
    42541 taatttttgg gttcctttcg aataaagcct gtaatggatc gaaccctttt ttagttcagt
    42601 tgctgaccaa ttggccgtga cttggtacga tgcagaagaa aggagctttc cccactgact
    42661 atcggctgtt aagtttgttg gtaaaaccgt tccgtctagc ttgtactgct ccaatacctt
    42721 taaagcaaca ggagaaagca atccgccttg cgcatctttc ccactgtaca cgatattggc
    42781 tgtctgattc aatccacttg tgcttgctgg agtatgagtc agtattgctc cttgtgtaac
    42841 gttttttcct gtaaaatagt tgactacgcg atcaaagcga ctaaatggca actgatcaaa
    42901 acgtccttca gtcagcccca tcgtcaatgt ccgactattg gtagagcctg gaaggttctg
    42961 gttatttcca tccacgtatt ctgtggtatc agcaaatgta ttatattttc ctgttgaatc
    43021 acttggtgag atgtaactat tccacgtatt tatctctgca cttgcagaaa atgcatatgc
    43081 tcctggattc aagtttccgc cagttaattt aggataaaat ctacctgcag ctggagctaa
    43141 aatcgaattg aacatacgat cttggataat attattcgaa tcataaaaat caacagaaaa
    43201 aacggccttt ttagacatag aaggttgtaa tttacccttg gtcaaaattt tgtttggact
    43261 cgtatcatat ttatctccgt tttctgtcat cttcgcgaca ttagctgtaa catcaaattg
    43321 aagcgggata tcgtccacgt tgaattcgcc tcgcgtaata atagcaataa tatctgtcaa
    43381 tagagtattt gtatcccacg accccatccc aaaacgcaag gtatggcttc ctgctgataa
    43441 taaacttccg ctagtaacct tgatgggggc accggcaata tacaagtagg cgttgttcca
    43501 gtcaattgct tttaatacat cactgcttga tacatgttcc ggcaaattga tgatcgccac
    43561 aaatgcaaat ccttgtgcag tgatattcac caaatcaagt acatttgtta gtttcacatg
    43621 gctttcccaa tgaaaacgga ccgtgccacc tttccaagga tcatttgaac catcgttcaa
    43681 ataagtagca gtcaatttag gcaattggtt agccccagtt agttggacaa gcttcccgcc
    43741 attgactgca ctacgtccac catttggagg tacgatattt tcatacgtgt atggatcata
    43801 agaaatggca ggaggcgttg ctccaacagc ttctgccgaa ggtgaaaaga taaatatact
    43861 taaaacaaaa agcgaagtaa aaaagaagga gcgaaaaaat gaaaatttat tttgtagcaa
    43921 catgttcatc ctccttttcc tttcttctcc ataacaacaa ccacgcaaga agccataatt
    43981 ctataccaat gatcaaataa agaaaacgga tcttttgttc attcgtctcc gggaatacgc
    44041 catgttgatt agattcttta taaatcggta gctgtgtctg ctgttttgat gcgccattga
    44101 ctgaaccact tggatgcgga attggactta gatcataaaa tgtaatcgta cctgaacttt
    44161 tggtatctgc ttggactggc tcttgccagc tgaagaacag caaacttgca ataatccctc
    44221 ccaataagat cgatgttttc aacgaaatca cctcatcatg ttgtttctcc ttttttcttt
    44281 ttcttgtgga cccacaaaaa cagcaaaatc aaccataaca ctagaactgc agcaaccaat
    44341 cctgcataaa gccatgggaa agattgttct tgtactgcaa aaacggaatt ttcatttact
    44401 ttttgtgctt tttctttttt gatcgtaaag ttttgtgtaa atcgccattc attactgtcg
    44461 cctgattttg ctatgatttc tgcgcggtaa tcgccggctt ttgctttatc accagctaaa
    44521 tcaagattca agtgaaaatt cgaatttggt gcaactaaaa atgcattaga cgtattttca
    44581 atataaagct gattttcata aaagatcttg ctcgtaaata tcaaattgct gataatccta
    44641 ggctgaggat tttggaaacg aagctgaaca gttggctttg cgttgacctc gtccaaatct
    44701 cctgataaaa gtttcagatc cggttctatc gtctcttgac tttcttgtaa aacgactgcg
    44761 agattataag caatacgatt tttgatttgt gctccttctg tagcattttc tgtttcagct
    44821 tcttctttag gtgaaacatg aatacccgct aatacacgtc ccttaaagct ttttgctggg
    44881 attttcactt ctataggtac agttgtttct gcatgtgctg atacattgat ttcctttttc
    44941 gcaatgagca aaacgtcacg gacatcaaac ggcaatgtct catctaacgt tgggtttttt
    45001 tgactataat cgatcgttcc accatcactc gttaccgccg gattgacaga gacctcaaat
    45061 gttcgttctt catctgaaga attgctgata attacttcta gtgtctgatt ttgttccggt
    45121 gccactaata aatcaaaata accgattgct ttatctattt ggttctctgg aaataccggt
    45181 ttgattccaa agtctcctgc tgaatccttt gcttggctga ttgacggaaa aatgaaaaat
    45241 agacttaaaa tagaaaaaaa cgaaacaaac agtcgtttac tttgattcat tgtccaccac
    45301 atcctttcaa caacaactgc ggtaaaaaat ccttcaccta tagtattttc accgcagttt
    45361 gttgaattta tttcatactc tatgctactg ggccagccac gaggttccaa gtcaaatcag
    45421 ccgtgaatgt tccagctgct gctttcggca ctttcagtgt gatatttgct ggatcataaa
    45481 cagaaagcca tgttcccaga ccttgatctt ttgctgctgt aaatattggt gtcgctgcac
    45541 ttgctttact caacccagtt acagtttgac tagttggtcc agtggattcg ttatctgacg
    45601 tacttttaac agtggatgtt ccaaaatcta attcagcgcc ttgcaaaact tgtgaaccgt
    45661 ttacaaaatc tgaaaccgaa actgtcacgt tccacccttg tgcttggcca tctgcaccta
    45721 cacctcgacg atctgatact tggagataag gtgtatcgtt ttttgaagcg tctacttgat
    45781 acgtttttgt tccgctttca atctcgtgtg taccaaatgg caattcggga actacatcca
    45841 gtgttaaagg acctgtctgg ccagttgctg gattttccgg atctgctggc tctactggtt
    45901 ttgaaggatc agtagggtta agaggctcca cggtatttgt tggttcagta aaggtaatat
    45961 ctccttttga agtcgcttga ccctcagcaa aagctggtgt tgccaagccg cctagaagaa
    46021 gtgttgaaag taataatgtc ccaatcatgt tctttttcat aataaatcac tcctttttct
    46081 tagtgaccta agtatagtag agacagtatg caaaaaatcc tcatgaattc atccgcttac
    46141 ttgaaattat gacccttttt gtataaaaga gaaaaaaaca ataaaatcgt ttacatgaat
    46201 attcttcctt ttttattaag tttcgtttgt caaattaagt tagacaaatc atcttttgtg
    46261 acgtaactca aaaatacttc cattggtgtc cgatagtgta atgattttct aggaatatga
    46321 tttcgtttcg atgccaccga ttggataaag gtttcagata caccattaaa atccatagct
    46381 ttatacaaac catctttacg taataagcca tttgaatgtt cattcaatcc tcgttgagaa
    46441 ggtgttcctg gatccgcaaa ataaattgaa atatcgttgg tattactaat ctttttccaa
    46501 tttgagaatt cttttccaca atcaaatgtg atggatttaa ataagttttt tgggacacaa
    46561 cgaaaccatt gattcagcct attttcaatg tctttagcct gtctgccttc gggtttcaag
    46621 gtaatgatga ctttagatag ccgttcaact aatgtgatga ccgcgctttt atgttttcca
    46681 cccacgatag tgtcaccttc caggtgacca aattcatgat caaactgggt atagtctgtc
    46741 tttctgtctc ggattgaccg gcgaaaccct tgttttcctc ttttttcttt atgaccgttt
    46801 ggttttcttt ttcccttcat tggtaaatcg tgagtgtcaa aggttttatc tttaaacatt
    46861 cgatacagtg tgcgtaccga acaagcaata ggaaactctg ctcgaccaat aaggacatca
    46921 ggagcccacc cttgaacaac ctttttttga atgtattcct gttgctcatc aggtaaaaca
    46981 atcggatgtc ttccgcagtt acgtttgttt ttcttatatt gtttatagta gctcattgcg
    47041 cttccaccag atttaagaaa acgatagacc ttataaatag tttgtcgaga acgttgtaac
    47101 agattggcta cttttgaaac aggttgtgat tgattgaaat aagcttctat cattacgagt
    47161 tcagttggtg taagatggtt ataggtcatt tgtactcact ccttataatt ctttcgtcgg
    47221 aactattttg agtgtagcac aaatgacttt ttttagttgt ctagcttaat tttacaatcg
    47281 gcgttttaaa ggcagtaaca ggattaaaca ttgaaacata atcgttacta aatgaaatca
    47341 agaaatatac tgtattactc aattcattga aaatatttat cataattttt aatagaaaac
    47401 actattaaag agaaaaaaga gaggtaaatc aaatgaaaaa atctttaaaa cttgcatcag
    47461 cagttatatt aatgtcccaa ctccttatag caacaccttt ccatgtgttg gcaagcgaaa
    47521 attcaacata caaaattgca aaagaaagaa ccgagacgac tgaaatgagt aattccgatg
    47581 taacagcaga gagtagtgaa cttttgacaa cttcatcaag tgaaagtagt acgacttcaa
    47641 atgccgagtc ttcaacaact tcatcaagtg aaagtagtac gacttcaaat gccgagtctt
    47701 caacaacttc gtcaagtgaa agtagtacga tttcaagtac cgaatcttca acaacttcaa
    47761 gtagtacaag tgaaataact tcttcgaaag tgacaaaacc aaaccatata gaatcttcaa
    47821 aaaaggaagc gccaaaaacg gaaggacaaa caaaaacttt ttcgacacca cagcaaatag
    47881 aatcaacaga atctttccaa tcacaaccaa tactatctgg taatgaagaa attcattttg
    47941 acaaaaatga atctgtagaa aattttatta tgaaaattgg tgagtctgcg agaaaaattg
    48001 gtcagaaata tgatttatat gcttctgtta tgattgcaca agcgatctta gaatctgcca
    48061 gtggtcaaag ccagttagct caggcaccga attacaattt atttgggata aaaggaactt
    48121 ataatggaaa ctttgtcatt atggtaacaa acgaagattt gggtaatgga acgctttata
    48181 cgacccaatc aaaatttaga gtgtatgaaa actatgagga aagctttgaa gattatgcca
    48241 aattattaac taagggaatt agtggaaata aagattttta tgcaggagca ttaaaagcta
    48301 atagtaaaac atatcgagaa gcaactaaat tccttacagg acggtatgca acagatacac
    48361 aatactattt gaagctaaat gaattaatta aaacctacga tttaaccaac tatgataaag
    48421 aagttaaagg tccacaaatg agtaagactg gataccaagt gcctattcat aattattcaa
    48481 taaccagttt gtttggaaat cgtggaaatg aatttcaccg aggacttgat atggcagcta
    48541 cacagggtga gccgattcat gcagttaaag ctggtaaggt tgttaaagca gagtttcact
    48601 actcttgggg aaattacgtg gtgatacaac acgaagatgg atcaaccgcg ttatatgctc
    48661 accagcaaca atacctagta aaaactggag ataatgtttt gcaaggacaa ataattggct
    48721 atgtaggaag tactgggaat agtactggcc cacaccttca tttggaaatt tgcaaagata
    48781 gtagtctttc tcagagcatg ttagttgatc cgaaaacctt attattcgga gactaaaaaa
    48841 ggtaatcaat ctgacaaagt aacaagaaaa tggttggatt cttagacctt tgatcaggat
    48901 attgagactg gaattgatat ctcgattacg atgggtttga caaataaaac aagtccatta
    48961 tcgaatatcg agtgtattat tgccgtcttt atgctcatat tttgagcagg tttcactaga
    49021 tgaaaacaat ttatctatct tgaggatttc gtgtacgtat cgttcagtct tgtattgtaa
    49081 attagtcata aaatcagact aagaaaaatt ggaaatattt ttttctgatt tattaaaagt
    49141 taattgaaat tatatggtac ttctttcttg ggagggtagg tgcagtgaag gaaagatatg
    49201 gtcaccttac tgttgttgag gagattactc ataatggata taaaaaatat cgttgcctat
    49261 gtgactgtgg gaatgaaacg attgtatatc gatcaaactt actaacaggt agaaccaaaa
    49321 gttgtggatg tggaaattat aaaaataggc ataaatataa aaatttgaca aataaaactt
    49381 ttggtaagtt agttgcaatc aagccaacta aactgcgaag tgaaggaact gttgtttggg
    49441 aatgtcaatg tctgtgtggg agaaaaaagt tagtatcggc aaagcgactt ctaaaaggtg
    49501 atgtaaaaag ctgtggatgt ttgaaatcaa aaaagcatca cattgaaaat aaaaaattcg
    49561 gattacttac tgcaaagtat cctttggaca ataactgttc atggaaaaca aaatgggttt
    49621 gtcattgtga gtgtggcagt atgtgtgaga taagttatag taacttattt tttggacata
    49681 ctcaaagttg tggatgttta aaaaggcaag aaacaaggac atgtgttgaa gggacagtaa
    49741 tagagtgtct aacgtcaaaa ttaccgaaaa ataatacaag tggtgttaag ggagtttatc
    49801 gttctaaaga gaaatagatt gcgtatataa ctttaaaaaa aaagaggtac tatttaggat
    49861 cgtatgattc tattaagagt gcagctcaag ctagaaaaga tgctgaaaat aaattgtttc
    49921 aacctttgat tgacaaatat cgaggtaatc attaattatt gtggataata attaacagtg
    49981 atatataaac atctataata tattattcat actattgata tttagtataa tcctatggaa
    50041 ttgaatatca tagcaatgta tttgaaaagc aaattggaaa acaaataggt gcaacaccat
    50101 aaatatgaaa aaattgggaa aaagtagaat ggaaatttgc ttacgtctca cgagatagct
    50161 cacactatta atctgaagaa caatgaagtc gacttttaga aattgctaga agaaagtaaa
    50221 gcgaattatc actagttact atagagtaag ttcaaataaa gcatctccaa cttacatggt
    50281 tacatgagga tatcaaatcg aaattactca agcttcctat ggctagagtc gcgagaagtt
    50341 gttgggcagt agacataggt tatattgttc ttagctacac gatcattaga aaggaaatcc
    50401 tattatgtat agttatcaag aagatgcaaa agtccaaaaa aatcgctggt ggattttgat
    50461 tgctatatct atgtttacct tcatgtccac attggatggc agtattgtca atattgcact
    50521 acctaccatc tcagatgata tgggcatacc aatgaatcaa gcggaatggg tagtgtccgt
    50581 ttatctgatg attgtctgtt cttgtttgtt gctgtttggt aaaattggcg atagccgtgg
    50641 gaaaatcaaa gtatttcgga ttggtacgct gatctttgtc ttgggatcgc tgttgtgtgg
    50701 gttcaatcat tcgctaggta ttttattgtt cgcacgggtg gtacaagcca ttggtgctag
    50761 tatgactatg gctacaaatg ccggaatcat cacggaagtc tttcccatac atgaacgtgg
    50821 tcgggcattg ggagcaatag gtgcgtttgt ttcattaggc tcgattgctg gaccaggtct
    50881 tggcggcttg attttgtccc aattttcttg ggcgtacatt ttttggatca atgtaccggt
    50941 gggaatcgta acgatgttga ttgctgaaaa attcttacca aaagatatca ccatgagcgg
    51001 ccatacaatc gatggagggg gctttgctgc cattgcggct acgattatca gcttttttgg
    51061 agcaatcttt ttggggcaag aaagtggctt tttccatcca gtcccccttg tactgttcgt
    51121 aatttcagtg attgcctttg tcagcttttt aaaagttgaa aagaaagcag cctctccatt
    51181 gatttctttc ggtattttta agaacaagat ttttaccatg agcttgatta cagccttgtt
    51241 gattttttct tccaacttct ttgtcaatgt agtgattcct ttttatctgc aaaatgctcg
    51301 cgggttgagt cctagctatg ctgggctgtt gatgatggtc tttcctttga tgatggtcgt
    51361 cggggcgcct ttaagcggct acctgaccga ccgggttggc ccggagattt tggtattagt
    51421 aggcttgggc ttattgtcgg taacccaggt catgtatatg tttttgtcag tggactctcc
    51481 tttgtggcta tacattgtcg ctactgccat catgggtgcc ggcaatgcct tgttccagtc
    51541 ccccaataat acgatggtta tgagctcggt cactatcgaa aacttgggac tggcaggctc
    51601 gatgaattcc tttgcccgaa atttggggat ggtcagcggg atttcgcttt ctacgacggt
    51661 cttatatcaa gcgatgtctg ctaagatggg ccagcaagta actaactata tcgcaaatcg
    51721 gccggatgtc tttttatatg gaatgaagat taccttttta ggcagctttg ttttgtgttt
    51781 tgttgccttt ttcctgacta tctggcgtat caaaaaacaa ggaggtattc agaaaaatgt
    51841 ctgaaaaaac cactgttgaa gaatttttgg aggcctgcgt atgggtgagt gggatttcca
    51901 tggatgatgg aagatgaagt gaacttctaa aagccgaaaa actcaagtat tatcttcaaa
    51961 atactagtgc tcaatgagat gcttgatttg atcacaagaa gactgcgaaa gccgctggca
    52021 accgcaagct aggtatccca ccgatggact acgttttaga ggctactggt tatgaatacg
    52081 gagccaacgc tctcatctgc ataagaatac atcacccaga ttatgtaaag attttcgata
    52141 cttctgtcaa aaaatcatta agatagataa atgatttccg tctagtcaaa ttggttcaga
    52201 atgtagacac acagatggta agaagtcact cacaattcga gaatggactt gtcctatttg
    52261 ccgtatacat cataatcgaa acgtcaacga tagtatcaat attttgacca agggctatga
    52321 atacaagcat tgccttagaa aacatcaaga accttaggaa caacggggat agcttggtta
    52381 ataagagata ccgctgttta ggcttgcaag tatactcttt tatcaagaat tccgtggctt
    52441 tagtcatgag aggcttaata ctatgaaaat tttctttagc atttttgatt taggttcctt
    52501 ttctaattat aataagatga ccactacagt aacctactga aatatataaa cagccactgt
    52561 agtaccattt tcaaagtagt ctatgagagg agaatcttca ttcttatgaa cgctggaatt
    52621 gcggatatga atttaataaa aaaaaccctt aatgatttta cttccaattc aatatcaaaa
    52681 ggtactggta tcaatttaag cacaataaaa aagctgaaaa gtggtgaaag atcagtggaa
    52741 aagctgaatc ttttagatgc tataaaaata acggaatttg ctatgaaaaa tggaaaagct
    52801 gagattgaaa tatggagata attatcgtct agtgaattac ttgccactta gctgaattta
    52861 acgatccttg gtgcttgaag ggggagattc ttgggaatag agcatacttg caagcctatg
    52921 tctttactaa caacgatatc tcttattaac caagctatcc ccgtagttct aaggctttta
    52981 cttttatcta agcaataatc gtattcaaag gaaatttttg acccttagaa agtctcattt
    53041 tatcagacgt gagcttaggc attgctgaat tttgttaatt cggttttagg ttgtgctttg
    53101 agcataatat gaaagtattc tttatcacga tttcattcat ctaaggtaat gtgatgtgat
    53161 tctgaaattc tttcaaaggc agtttttgca taagctgaca ttacatcatc aatgacatgt
    53221 ttacaatgtt tcactactaa aataaggggg taaccaagaa gaaaaactga atgattattt
    53281 gtatctaatt ccatggtata tcaaccattt cctatataga ctgattatga catggattaa
    53341 aataaaaagg cactatgtct taattgtcgg ttttcgagtt accgaatggc attcatcacc
    53401 cacctataga ggatgggcga cttctgcctg aaataagtta cactacttat aacttctaat
    53461 aaaattagat tgagtcatta ttatttaaca tcaacgattt tccagtttcc atttttttgt
    53521 aatactaatt tgtactgaaa gtagctagtg gtttttgata cattatcaag gtattttatc
    53581 tttgtactca ctagaaaatt ttttccgttt tgtagataaa ctggattctc taactccgaa
    53641 aactttaagt caatattgat tggtcgcatc gcaccatttt caacataata ctccaattct
    53701 ttttcagaag ctgatggata aagtttaaaa aatgtttcta aaaaatcggt gatttcttcc
    53761 gttgttttgg catcaatttc tgaatcgttt tctacttgtt ttgcttcata ttttgccttg
    53821 tctggctttc caatcattgt tggcaaacta gttactaaat gattcctgtt ttcatcttca
    53881 aagattgtca ctcgatatgc agaagaaatt gattgcgtct tttttccctc tgtaatatgt
    53941 tgctccacta aaaatgaaac gacaaattct tccgagtgtt tttcaacatc tagaattttt
    54001 acagattgaa cttcggaact cgtgggaata tctgctcgaa ccatatcttg gattaaagcg
    54061 agaccgtttt ctgtaaggta ctgttcgaga ttactcattc tcttttcaat tgcttctttg
    54121 ttatttttcc atgaaaaata ttctttcgca aaatcctctg taaaactttc aacgccagaa
    54181 gtattcacta ccttctcttt tataaccact ttttcatgag ttgtatgttg atcaatggcg
    54241 gtgaaatttt tataaacgcc aaaagcaaga ctacaagaca ataaaagcca aagggcaagc
    54301 accatttttc gatgcttacc cacggataca actcgttctt ttttcttttt tgggctcttt
    54361 tccttttgat tccgttcaat ttttatcttc attctttttc ctcttttctc ttatttgtat
    54421 cggccagctc cgataagatg ctgccgccaa tagttttccg ttagattcgt ccaccccact
    54481 ggatctcctg catgaaacat gcgattctcc cctgcgtaaa tgcccacatg ggtcacataa
    54541 gtaccggcat cataggttga atgaaagaaa actaaatcac ctggtttggc atcttttaga
    54601 tcaatatgag tcatggcatc atattgatcc tgagccaccc gaggaagttt caggtcaact
    54661 ttggcataac accattgggt caagccacta caatcaaacc ccgtttctgg acttgagcca
    54721 ccaaacacat aggccgttcc ttcatactta aatgcctcat caaaaatttc ttggactatt
    54781 ttgtcatcaa actgagttgt agttaggtat tgcttcacta ataaacagta aaacatattg
    54841 ccataattat accgccaccc accattttcc ttaatcgcga ttgggttggg gtaatcgact
    54901 ttttgaccac ctgatttttc ctttgaaaaa gattcagcta aagcaaaact atgcttcttc
    54961 ccgtttttcc cgacatgatc tagatacccg ccaccatagt tataggcctg aataatacta
    55021 tcttgatcac accctagttc tttggaacgc ttaaccaaag acgcaaaata gagacagcct
    55081 tgtttgatgg atgcctcggt acttaatgaa ttaggtggta atccggctga ctcagaactt
    55141 tgcataacgt cttccattgt gccaccagat tccacttgaa taatcgccaa aagaattgga
    55201 atatactctg ttatatccga ttctttggca tacttttcca ccattgcacg gtgtttcaat
    55261 acttcttctg agacactagt tccgccagga gaagtgccag aactaccatt tccctcactg
    55321 tcttcaccaa acaacaaacc cacacacatc aaaataccca taaaagagat ggtcagaaaa
    55381 gttaatgaaa taacacccac tttcttcaag ttcatttttt ctcacctgac cttgattttg
    55441 gacgatggtt cattcttttt tgtacttttt gattggtctg ctttggcaga gtggacctct
    55501 gtttcacttg ttggaaagaa tttttcttac ttgctgattg gcttttccct tttgaaatga
    55561 tttcttgact agttagtttt cgtttgattt cgggattcag atttgctctc acaatccgct
    55621 ttggtgcttc ttttttcagc atcatatctt tctgaggttg agctgcttta tctattggaa
    55681 tattcgccct tctttttccc tgacgatttg ttgcttcact cagtatcttg cgtttttcgt
    55741 ccattttcgc atttcttcgt tgtcgttgtt tttctcgcaa atccactcga tccgcttttt
    55801 cttggaacag tccgcgcttg aattcttctg gtgctttttt cgacttttcg attcctttat
    55861 ggagattgta tttcaaattc gttggcgtat tccttacctg atcctttact tgtttagtct
    55921 tatctttcac caaagcttgg gtatccaaaa ctttgccgat ttttctccca gccaaattca
    55981 ttcgggattg tttcttatta tttgaaactg gattctcctt agttaagtca gatagtattt
    56041 cgtgatcgtt cggtaatcgt gaattctttc gtagagaaga accggatggc ttaaatttgg
    56101 attttgattg ttcctttgcc aacttatttc cgactgctgc accaccacca aaagccaaag
    56161 ctcgtcccac atttcgattg agttgccgca attttcgatt cattaacatt tgcggttttc
    56221 gcatgacgcg tcttcccatt gactggctat cattactctg gaggttgaac atactcataa
    56281 tgtcgcccaa tttgaaatag ataccggcaa aggtcacaat ttgcagaaaa gcaaccatga
    56341 aaaatggata ggttgccgaa atattgaaaa acatcgtgga gatgctaaat gcagtcgtaa
    56401 tcaccaaagt aacacccgct cgcatcataa tcgtattgaa taaacgaata atcgccttct
    56461 ttcctaaact ttcataagtc ggcaacatgg acaataagaa actaattggc agaaacatcg
    56521 caaagataat gaagagaatt tgcgagaaca acataatccc tgttagaaga aaaacaaaga
    56581 aggaaatgcc aatattgaac aataccaaaa agaccacggt ccctaaacgg ttcatggtct
    56641 tggtaatact gagattcgca ttgtcattgt cttcaatctc tgccttgacc gcttcttccc
    56701 gatctttgcc tttgttttca tctggactca cagatagaat cttgttgacc cggtcttcac
    56761 caatttcttc tatgttggaa tcatcaaatt gcagtagtaa ccaaggttgt tggacttgaa
    56821 tcgaaaacaa actatcccga atcaaatcca cactatcttt tccttggctt tctgaattgg
    56881 gtacaacgat ctcggttcca agggtaaggg ccgcttcact aacatctgag ctaaagtcat
    56941 tgatttttgt gatataggta ggcgcataag caatgaacga acccgatagt agaaaaatca
    57001 tcacaaaatt aatcacggct cgaactgctt tcgtggtttc tcgttttaat aatccggtat
    57061 acgccacata cacccccaga gctaaaatca tcaataatag aaacccaaaa taaaatccgg
    57121 aggtctggag tccattttca gtaataccag ccaatgtttg gatattcttt ccaatacttt
    57181 cagccgtatc cgaaatgaaa tctaatttgt aagcctcttg aaccacataa cccgtggcgt
    57241 tcgacaaata caaactcacc gtccaaatga aattagtaat ggcataaaga ccatacatca
    57301 cgcttttccc taagccatca ccccaattcc aaggcaacca atcccaagag ctatccacaa
    57361 agaaatctag ttgatagttg ttcagtgaat atttggaata tagatttcct gcttcaactg
    57421 tatcatcaac tagccctgtc gcctcggcta ccgtaccaac taaactcaat agaactatca
    57481 gagtgagtat gctaataaaa acgattccca caatccgaaa aagtttcttt ttcatcccct
    57541 cactccattc tctcttgaac aggtggacgg gtatcaaagg catggaagag ttcttcaaag
    57601 actggatgta cctgaaccac gcctacccga ccatacaaat cctgcatcaa gcattggcca
    57661 ttttccaaat ctcgtaggcg tttttgattg ctttcatctt ctcgatccaa gccaaagaat
    57721 tccaaggttt tcttgatttc atgaatatcg gtactgcgaa acgcaaactt caacccgata
    57781 ttattcttca agcgttcatc cagtaaatca tcactatttt gcgtgacaaa gtaaaccccg
    57841 gcattcatag cccgcccagc acgaacgagc ttattcgata atgttttccc ttgcgctact
    57901 tgaagaaaac tccacgcctc atctaagtct acaattttga agatttctcg attactatgg
    57961 ataaagtcca aggcaaaagt ggaaatgacg attagcatgg aaacactaag caattccatg
    58021 gtggtatatt cttcaaaagt ggtttctgca tctggtaaaa ccaaatccgc tacttgaatg
    58081 atatttaact gcctatctaa actaatcgac tgggtaatcg aaccatctga gaaaagcaaa
    58141 tgggcaaaat cataatcggt aaaggactcg atgtgatccg cgatattttc cgcaactggt
    58201 gagccttctt ttcgaagctc attaattact tgtaataatc cccgttgatt gctttgggta
    58261 accgtccgaa tggccttacg caacactgga aacttctccc catctcgact agaaattcct
    58321 gttaaaaagg tcagaatatc aattgctaga ctttcagaat ccttcttttt ctccataatc
    58381 acataaggat caagtaatcc ttgatttttt ggcttactag ttaagttgag aatattgatt
    58441 tcatccgcaa tttctggcaa ggtttctttc cagccacccc gttccccttt tggatcgaca
    58501 atcacagctt gtccaccaaa aaggacggcg taataaacta agagattgtt actaaaggac
    58561 tttccgccac cgagtgaacc gaggaatgcc gctgctagcg cattggtaac tgaatccttg
    58621 accccttgtg aggccaatgc cggtttcagg taaacattgc gccccgtatc tacgttataa
    58681 ccaaagtaaa tgccttccaa ctcccctaac atctgagtgg cgccaaaacc aagtccggcg
    58741 agaaaatcag acgtaacata ctggatataa tcattcatgt atcgcttact agaaggtaag
    58801 aattcttcat gtagccccat catatcgcca aaaggccgga ctagttttac attggtatca
    58861 tcataaaaat ctagcacttc atcacaccgg cgctttagtt catctactga ttcggcactt
    58921 actcgaacca catagctcag tttgtacatg gattctttgg actgatccaa ggtagtttcc
    58981 aattcatcta cggaatccaa tgcatctaag acattggaat ttgtttcatt gtcagattga
    59041 taggcatggt tgtccaagtc ttttaattcc tttttcttat tgcgaacggt agcaagtgcc
    59101 tttttgttcg tcacaatctc cacattcata ctagtgtcaa ttgggaatgt aaattgttgt
    59161 tgctggtaat agaaaagttc tgaggaggga aactccattt cccccacaat tgtattaatt
    59221 gttaagtacg ctacatatga ttcatgattc tcatgttcca tgcataagta ccggggcttt
    59281 tcttcaatca aacaacgact gggacgtaat aagtcgtaac gtttcaccaa agtttccgac
    59341 ttcagctttt tctttggtag ctgaaattca tattcttcaa atggtgtacc cttttcgcca
    59401 tagatatgtt caatcaaata catcagatca ctcggtgtga ctcgtctgac tttaaatctt
    59461 cgagccaatt tactttccat tagtttttca agcttggtat atcggcgaat ttcttcattg
    59521 gataaggaaa caaaatcgcc catcaaatga tgattcactc catagacaaa ttcttgaaag
    59581 ccggagaaga aagatttctt gagattcttt agattgacct cttcatctgt cgcaatcagt
    59641 ttgaagccaa taaaaaagcg ataatcaatc tgactatcgc caatcatgga tactaatgcc
    59701 tctgtctgta aatcaattcg ttgtttcgct acttctgtta atcgcccggt aatttccttt
    59761 tttgatcgtt cttgcgtggc acgaatacta ctttctgtgg caatttgtaa ggcatgaatc
    59821 ttgccttcac gattttgcgc aatcaattga cgaaagttat cgtggacttg atatttctgt
    59881 tcaggtgaca aaaaggagta attgtaaggt attaactcat agtaggcaaa acattctccc
    59941 tcttgattaa agacaagatt attttcaata tacttaatcg ggtacatagt tcacactcct
    60001 taccagagta atgggttcgt cccatcgttt cttctgttct ttgactttct ttcctgcgaa
    60061 agtgacctta aatcgtaagt gatagctaat aaaagatcgt aaaaatccca atggtttctt
    60121 accgtcaaac gttttttgcg acatgaacca agtaactgcc accggtatac ctaagtattt
    60181 taaaaaggcc ccctctatca tagatagtgg aggcacatgg gcaaatacga tgacaaacag
    60241 caaggataaa acaaaccaag ccatctggtt aaaagtcaca ggaaaaggca gttgaaagtc
    60301 attaattgca taaatgacct tttcaactgc ccaaatactg gtgtagcttt ttattttctt
    60361 catcaaatca ttcctttaaa aagaaggata gtttagaaat caactaccct tcaataattt
    60421 tgttaatatg gatactcaaa aacacctcga ctcgttacca aataattgcc tccaatctcc
    60481 aagtctctac cacacgcatc aaaatcaata tacgtcttca agtgttctgg tacttctcca
    60541 aaatcaccag cttctacaat caagaaatat gctacatcac tcatatcatc gcaatctgga
    60601 taatagataa tatcatccac atgctctacc atctcctcaa aagaattgaa gaaagcatgt
    60661 tgaatctcag aagcaacttc accaactggc gttccttcaa gttcctccgc taagccacac
    60721 aaccgattaa tttcctcaat tggcgtatac tcatcaatct caaagggaag ttcataatca
    60781 tgaattgcat attcctcgta ttcgtcattt aacccaattc gttctttcac ttcatcaaaa
    60841 tcgacaggtg gggtaaacca cgcccccacc aattcacctt cgttatattt cccgaggttc
    60901 gcaatataaa cacgcatctg ttccatcgtg cttccccctt acgcaccgac aattcggtta
    60961 aacaaactga gtaagacatc cttcacccca gaagcattaa agaccaatcc gaccgcaatc
    61021 aaagcaatca ccaaaaagcc aatcagtttg gaaaactccc gcttaaatcc taaaaacaaa
    61081 ccaatgacca caattgccag taagactaag gattgggcat tggttaaaaa ccattgatat
    61141 atggataggt aagttcctga tattataaat atctcaaact tttcccccca ttcacacgga
    61201 gcgtgcgact ttcaccgcac tccgcgttcc atcgtgttta tattgaaaag tatttatgta
    61261 gtagacctat atcaagttta attcttgatt gccagctaat actctatatt tatttagtct
    61321 tatgagctgg actttattta gcttcaatag agctatatat ttttgtattg tttcttctgt
    61381 tttagcgtgt attagacggt gtaccgcctc ttttaccaaa ataagatttt tataatcgtc
    61441 atttccacca gctccagttg gtacaatatg atgacaatgt atttcattag cttgttgaaa
    61501 ttcttccaga gttatagcac attttccatg ttgagcagaa aatagcgaaa ttcgattgtc
    61561 tgcgtattct attgtgcgat tttccaaaga taatttcatt aactggtaca tcagtaattt
    61621 atcaacactt agattggtgt ggataaattt tcttccctct agagtgtagc aattcgctaa
    61681 atacaccttt gccattggtt ttctgtgttg gatatatcca acagggaaaa taggttcgcc
    61741 ctcgccagca acataccgaa gcattttaga tttaccatat cttgttgcct cctttgtcgt
    61801 aagttgtctg cctgtttttc tcaatctgcc ccttttgttt gtacctaatc tgttagtgaa
    61861 gatagccatt acagctctat tcagtttcat acaatccaga tttacattcg ttgcaatctg
    61921 ataataattt tgcataccta ataccattga attataaagt cttgtttctt ctaattccgt
    61981 tttccctttt gagggagaag caattttctt tgcctgtgat accagcttgt ctttttggtt
    62041 tttgaattgt ttatcactta tatgtgattt aacaactaac ttctttcttc tcggtatcat
    62101 tttaatcttg aaaccaagaa agtcggagta tctttttcta acatttacaa ttcttgtttt
    62161 ttcttgtgat acttccaatt ttaatcgttg ttcaatccat tgagtgattg ctattttggc
    62221 tttttcagca ctttccttgt agcggcagaa aactctaaaa tcatctgcat aacgaaccat
    62281 atacatttcc tttaactttg ttttcttcat ttctttgtaa gcgttgcttt tacatgggct
    62341 accgctttta ttgatatgaa ccacatagtt ttttgtaaca ggattttcct gccattggct
    62401 ttctacccaa tggtctaact cattaagaac aatgtttgct agtagtgggg atattattcc
    62461 cccttgcgga gttcctttct ctggatatgt tattgtaccg ttagtcattt tgattggagc
    62521 ttttaatatc ctttttaaaa tgaatatcaa gtgcttgtcc cgtattccca tagcccatat
    62581 ctgttttatc agcttggaat ggttcacgtt gtcaaagaaa cccttaatat caaattcaat
    62641 cacataatgt agctggctga tttgtaggcg gttataggtt gcttttattg cattttcaac
    62701 tgacctatta ggtctaaaac catagctgtt ttcactaaat ttagcttcgc agattggttc
    62761 taatacttgt tttatacatt gttgtataag cctgtcccac atacaaggaa tacctagagg
    62821 tctggtttta ccatttggtt ttggtatttc ttttcgcctc actggcttag gtcgataccc
    62881 atgtggactg cctgcaacaa tgtatcttac ttttttgaca actgtttctg ctggcaattt
    62941 gccaatatct ttaattattg taccgtctgt tcctgctgtt ttactgcctg catttgcttt
    63001 gatatttcga tatgccagta atatattttc tctcgatagg ataatatcca taagatgagt
    63061 gaaaatatct ccattcttac ttttggcata taaatcatca aaggtgtttt gcatttcgta
    63121 atattcagcg tgtcttaaat cttctacaca caatgtttca tttttatttt taggcataag
    63181 gcttcactcc tttacttgaa attgagtgag cttttttatc ttactcgtaa tccttattga
    63241 aacaacataa tacttttcta atatatacac gacttgaggg cattcctcca ttctcattac
    63301 aagaatttct taggttcgcc ctctgctttt cagcattagt tcaactgctt attgttcttc
    63361 gtcagtttat tctcttgatg agaacccaat acctttcctc gttccgataa tcttatctat
    63421 acatatatat ccttaggtca ctagctataa gcctgctggc ttgataccgc ctgtaacgtt
    63481 atatggcatt tcataaccta tattcttact ttgccacacc agctacgatt tctcgtacct
    63541 ttgcatttct acaaagttca aatttagacc cgtacattcg ctgtttcgtc agttccttat
    63601 agaacattct aaccatagat attttataga cccccgacct gttggatacg ctacccacct
    63661 ctggatagtt ttcgatagaa gatatatgtt catcaactat tacggtatct ttcagccgtc
    63721 tttaccgagc ttcaaacatt ctgagtttcc tcatacaatg cttgtcggag gctcagggca
    63781 ggcgtttcag agcgttactt catcattcca cctgtcagat tatcagttct cctaataacc
    63841 aaactttttc gttcttttat tagtgcctta gcttttcact aaggaacgag tcgcacataa
    63901 attttgtccg aaattcatct tgtcactttc ctttcttttc cattgctcga tccgctgctg
    63961 cacttgcatt catcaagcac atcacagtaa caccaagcat actgccacca aataccaaaa
    64021 aaatatcttt tacaattccc atgacgattc ctcttttcat ataatcaaat tttcaattgc
    64081 catactttgt tgctccaaaa tctttttatg tcggtctgat aagcgtgcat tctgtaccat
    64141 atcctggata taggttgtcc gattcaatcg atccaactcc ttagccattt tccacgtagg
    64201 ggcgacttgt cggcctagcc aattcaaggt tcgttcaatg gtatacggtt ttggctcgga
    64261 agttaattga atctctttcc gattccgtcc aataaaacgc ccccattgtt cattcaaggg
    64321 ccagttggtt cgccttttac cttctacttt atccgcaaat cgcaagtaac gattgataat
    64381 ggaaaacgtg gtgctctcaa tgctacgacc ttttaacaaa tcttgaatcg catgaaaagc
    64441 acggtcattt ttcagtcgaa tctcaaaacg atttttcgtc tcagtttggt ctaatggaat
    64501 ccctaacttg atatattgtt catagtcttt ttcatacaaa cagaaataaa cctcactctt
    64561 gagactgccg atatataagg tattgcccat gccgtccttt tcatcagcct ttaaaagttc
    64621 cccggaacga taacttttaa aggtacgaaa caaggagata cattcttcct tctgacattt
    64681 tttcgttagc tcaggtatat ccaatagccc cactcgatca ttgattgcca agtccaagcg
    64741 tttcatcacg ccaccggcct ttagacaatc ctcgaaaaag tcgtaccagc tacgcttttg
    64801 agcgagtaaa aaagtttcaa attgtcggca acctcgcccc tttaattcta aaagcacacc
    64861 tttatcttct tcatgagaca acatcaccac aatatcaccc atgacatact gttcttgata
    64921 ggagtaaaag gcataatctt catggagcat atactcaaat ttcaaatgga gaatttcttg
    64981 aataattttt cgtgcatccg ttgtgggaaa gcgaatcctt acatagtcaa acagtaacgt
    65041 caaaggcaaa tcgggattaa agctttccag ttggtcaaaa attttcctca tggtttttat
    65101 agatgcggtt acgccaccat tttctatctg atttaagtac ggccgactaa gtccacaagc
    65161 cgtagccaat ttattttgtg aaacgccgta ttcgttgcgt cggtctttta atagccgata
    65221 atctaaattc cgttgtgcca agttctcacc tccaaattca aggtgttaac tttttcaaat
    65281 gagttaacac ctatacaaat tacttactat ctttgataca acaagcattc ttaatggttg
    65341 cttacttatt ttttgtgttt ttgtaccccc ctgttagata cgggggtgag acatcatggt
    65401 cggctaacgc cgtccatgaa caggcacagc accacggagg atttctgctt cgcgaatcct
    65461 ccgcggtcag cgcctaacag tcagttgtgt tggtttaggt tactcatctg taataccatt
    65521 tacttccaac tctgctttca tttctaacaa gtattgacga atatctggtt cttttgcttg
    65581 gtccgcaatc cgctcaaatt ctgcaattac ttgatttatt tcaattcgag catccgtctc
    65641 ctcattcatt aaatatggat cgccagcgac tttgacacca ttcttgcgaa tatcaaattt
    65701 taaccgtcgc aattgttctt ctaattctgg gtctgactga atctttccaa tcacccaata
    65761 aatttctcca atcaactcat cataaaccat gtacatccaa ctcttttaat cttctggcaa
    65821 tatcaaaaat gaccggaact gttacagagt ttccggcttg cttatacaac tgactatctg
    65881 aattgacttg agaatctcga tcaaaagccc aatcgggaaa gccctgaagt cgccaacact
    65941 ctctaggtgt tagcttccga atttgatact gatccgtgac gatcgcttgt tggtctcctg
    66001 ttagtaaggt atgaacactc tgttttccca gacgacctcg gcgacttgtg gaattaggaa
    66061 aagccagatt cacactgtct tctggcttca cctcttgata ttctgtttca ttttttcgaa
    66121 tcatgatttt tgtaccacct tgtttcgttg acaaggtggg ggcggttcca gtaacttcat
    66181 aaactcgatt accttgttca aactttcccg gtaatagtcc tgctacagag attccatccc
    66241 ttgctggcag tgcgattttg attccttcat cacctgttaa ggttggcgct acgccatctg
    66301 aaccatagac ttgtccaccc attcctcgat tggaaggatt gatatttacc aaatttctga
    66361 tgttttgatc agatgttgaa gacggtccaa tgataggaaa tacttgttcg gtacatgcgt
    66421 ctcgagaatg tccgataagg aatatccgct cccggctttg gggaatgtag gcctttgagt
    66481 taagcaccta ccactccacg tcatacccca atccatccag cgttcggagg atcgtctcga
    66541 acgtagcccc tccttcgtga ttgagcaatc ctcggacgtt ctcaaggaat aaaagcttag
    66601 gtcggagaag agtggtgaac cgagcgattt caaagaataa agtacctcga gtatcggaaa
    66661 atctttgccg ctttcccgca attgaaaaag cttggcacgg aaatccgccg caaaggatgt
    66721 ccactggtcc gagggattga ataaactcat ctgatacact tgtgatgtca tgcatttcca
    66781 cctccttact tgtatcatga attgctttat aactacgtct agcaaattta tcaatttcac
    66841 aaaaaccgat acaatgatgg ctcgcctgtt ccatacctaa acgaaagcca ccaataccgg
    66901 cgaataaatc taaaaatctc atacattacc tcattcattg caaagaaaaa agccaagaac
    66961 attttgctct tggctcatac attattaatt tgtcctacta ttttttattt aatccaacta
    67021 atttccgttg tttttcattg gcctgatcgg ctacatattt aatcaccgtt ttgaactctt
    67081 ttgcagtagc attttccgat aaatccgcaa tgctcttatt gtatttcttt acaattttcg
    67141 ttacttgttc tttctcagtc atgtaattga acctccaaat ctttcctact ataccctagt
    67201 ggtaaaaata attctagatt atccgtagca taatgaactt cggaaatatt attcgtataa
    67261 tcttttatta tgatatgaag caatacatct ggatgtttac tctttacttt tgcaatgttc
    67321 tctcttgatt tgaaaaaagc gttaataaat gcctttttcg gcacatgacg tccctctgca
    67381 atttcacgtt cttgtgtaaa tttccaagcg attttagggt cttgataaac atagaaaatc
    67441 gtcactcgaa aatgtttttt caacgcccgc gagatatttt tttcagcact taatattgca
    67501 aaagttgcat ccagaataaa agaatagcca tgatctaaga catatctaaa tgcctgctct
    67561 accaaccaag aagatgcttt ttgaaagaga ctagagtttt ttccattata atcaggaaac
    67621 tgggtgcgaa agtaatccgc atcaataatc acatggttat cataattctc agctaatcca
    67681 atggcaacct ctgattttcc agccccagga ctccctgcca taaaaactgc gtctcgtcca
    67741 acttcggggg atttcccttt gataatataa gaaataaact tatccttatt tgcttttgca
    67801 tactctaaat aagaatcatt actttccata ttaattatcc cctttcttcc tactatataa
    67861 aagtattata cgttacttga agtataaagt cagtattgaa gatcactcaa tcattcatct
    67921 tttctaattt actaattgaa tctaagaaat catacccttt tggtacaagt ggcgtataaa
    67981 actcactaat cacactgcca cctgtatcca cataacctcg acctttgatg tgcttcataa
    68041 agaagttttt ttcgacctcc ccaaacatca tggaatatcc gagttcactc atacgaccca
    68101 aagccacgcg aaagttgaat tgatcgcgga ttccgtctcc taaatatttc gcatccggcc
    68161 tttggcaagc caaaatcaga aagaaaccag attgacgacc caacatcacg atttgtttga
    68221 gcttattcaa aatcaccgca ctttctttcg tcgttaacat ctccatataa gccacgtatt
    68281 catcaaagat taaaaagttg ggtggaagtc caagataggc ataattctct cctgttttgt
    68341 agttagacat ttctttcatt gccttgctac gagccatcat acgttcatag aaatcttcca
    68401 cacaagcaga aatttcttcc ttttgtgaat aaacatgagg catcaccgta cctaaatcag
    68461 ctaaatctgc atttttggga tcgaggataa acaattctgc atctgacttc aatagtgctt
    68521 cgataatggt gaggaggaaa taggtcttcc ctccacccgt gccaccagcg attaacatat
    68581 ggggtaaaga atcataagcc catacttgat ttttcatcaa tcgcagagtc ccattttctg
    68641 ccactacttc gtctatccca attcgattgg cgatcatatc atacagtaaa gtatactcca
    68701 cataggagtc tttgagttcc ttttctacta actcacaata cagtccgctt tctaacttct
    68761 tttccaattt taaaagctga tcttggtatt tcccaagtga aatttgaacg cgaatagaca
    68821 gtaatccatc tttcattcga taacagattt tggggaagta actgatagtc tctctggttc
    68881 ggctactatt caaatctttg aaaaagcctt cactttgagt ttgtttcact tcataccaat
    68941 ggttctctag aatcatccga gctagctttt gtcgatgcca caagcttcgc caatgatcaa
    69001 gaaaaaagtg aatataaagc aatatcatag ctcctgaaaa agcgagactt ccaagcagac
    69061 atactaaatc ttttatagac caaacgattt caatagtaga aagtgatagc ttagaaatat
    69121 caaattgtct aaactcttga aaataaaaga cgctcatcca accgatgaac agagcgagta
    69181 gccagccaat aacaaagtga taaaccaagt gctgatctcc tgcgcgtatg cgatgtcctt
    69241 tgtacatttt gatggtttcc acctccaatc gaaaaagccc aataggattt cattaggcaa
    69301 tttcaaaaag ttatgctagt catttactgc tacgaggagg ggagttgttt cgtttcaacc
    69361 aattgattta aaaagccttc aatagcatcc ggcatctcca caccaatttc ttccaaaatg
    69421 gattctgcct gccgacataa gttttcattt acttcgacaa ctataaagaa agactcttct
    69481 tctcctaacc agtctagtac atcagagtct tcttcactgt cgctattttc tccaagtaaa
    69541 ccttgatgta taatcagaaa cattttttca tcagaggtta atgctttaac gagttgttcc
    69601 tcagtcagct cgccttttcc atattgatcg agacaatcta aaatatgttc aacattaatt
    69661 tccataatct tcacctattt ctttctttca ttttggttcg taggatttcc ttgattcggc
    69721 tgccgcttca agactaaatc atccgcctta atgaaccaat taacggtagt tccttctcga
    69781 aaaacataat tggcaacggt atccacgatt ggattgacca actctacctc tgcatcataa
    69841 gcaaactcgc gtaagggtac attagctggg atactaactt gaatcattcg cccttgtgca
    69901 gaggatttta aattataggt tcgttctttt acctcattac caattgttcc atcctcattt
    69961 tgcttccgta cttctcggcg taatgcggaa aaacgcaact tcccaaatgt taaacctgaa
    70021 tctacgacaa taccttctgt taatctcatc ttcttttcct cctatgcttt cactaaatca
    70081 tcaacataca acacgtaatc agtaaaccca cgattctcaa tctcatagcc tttggcaacc
    70141 aaatggggat tcacggcttt tagcggttgg tcttgatcaa aatccttttc accggcttcc
    70201 gcagctacta ccacctcaat atcatcggcc cgttgcttac tggaatacaa atgataactg
    70261 cgaccaatca ccgtagtatt ccgtccatat ccttctgtta taatttctcc ttcaccggca
    70321 taacttaact ttccaaaggt ttcagccata tctggcacga caaatttcaa ttccatcttc
    70381 ttttcctctt ttcattgtta gttttggata caaaaatagc gcgactactt ttttaggagg
    70441 cggtcgcgca cgttggttct taggatttac ttgtatcatc tcatcacctt agttccggcg
    70501 attccagaaa taatagcccg ccgtcgcaaa aatcaaagta aaaccaatga acagtaaaac
    70561 attggaattt ttctccccgg tttgagggaa ggtcttcact gtgggactag attcttgaga
    70621 gccacttgga acagttggtg tttccggttg tttcggcgta cttagtatgg ttggaacttc
    70681 ttttggtgtt aaggtttgag atttttcttt caaatcttca ttgtgttttc cattgatatt
    70741 cccatcttta tcgtaattga tttccgcaaa agtaaacttg gttccttctg gatattttcc
    70801 ggtatctact tttttcgcaa gcacagtttt ggtgaattct ttatcattta cttcataatc
    70861 aatcttgcca gatttccaaa tttctttgtt tgtaccatcc ggtaataaag catacagaat
    70921 tgtttcgaaa gcttcttttg agccatccag tacatcatga gtaatcgaca catcatcaaa
    70981 catatccacc acatcaccat gagtaaaggt ctgagaaccg ttttctaggt gggcctttgt
    71041 ttggatagaa acatggtgtt ccactgtaca actgacagtt tgggcttggt tattcaagct
    71101 aacatccttc gctactggct tatcgcctgc ttcaaaagct tccttatttt catacacata
    71161 gttgaataag acaatagttt tatttaaaac ttgttcggcg gttaatttat gctgaatttt
    71221 ccaagttcct gttttctctt tgttcgccaa cgttgcgctt gtttctgcaa tcaccactgg
    71281 tttggctttt tcatcttttt cttgggcagc ttttgtcgca tccacatcaa tggcttgcgc
    71341 taccacatac cagtcttctt tgatttcatg tagattgtaa ctcaatttat caactagctc
    71401 ggtagaatcc agagaagtta attctttgtt tccgtctttc caagtcgcaa gagaagttaa
    71461 actatcttct tcctcaggca aatcatagag cattaaacgg ttcaaactaa cagaaaatgc
    71521 tttgttcgtc agcttctcgt aaggaacggt caccgtttta attggttgtt tttggtcttg
    71581 ttcggtaatg gtaaagacat actcactctt cacaaagtct tctttgtttt ccttaaaagt
    71641 agaacggatt tctaatggcg taatcttttg aaaaccttct ggggcttcta cttcttcaag
    71701 taaataatcc ccataaggaa gattttcaaa cttgccataa ccatcaaacc ctaattgctc
    71761 gttataagct gtggtcgctt catcttcggc acctgtgatt tcattggtcc cttccaatgg
    71821 cgacacttta aaggtcagat cattgaagcc agtttcggta gtgcccgcag ctgatccagc
    71881 aaatttaaag aaatcaaagc caaagcgaat cacttgttct tttgccgtaa catttcgggt
    71941 aatcacggca tttttttcgc tatcatccac ctttttgatg gatacaggat actttgtttc
    72001 atcaaggcta tatccttcgg gcgcttttgt ttcttggcaa taatactcgt tgatagctaa
    72061 atgtttaacg gcaacttggt tcttttcgtc taaagtcaaa gtgaccgttt catcagaacc
    72121 tttcgttccc ttcgctaact ctggtttaaa agcctcactc catttaacag cttttccatc
    72181 cttagcagta aacaaggtgt attcagcacc ctcaaagact gccttacctt gtgctttatc
    72241 cccagtatct ttgtcttctt tcgtcaaagt ggtttcgcca gtgacttctt gattttgccc
    72301 ttttacgtta ctggtaacag gggctacggt ttgattggca tacttcaatt cgacttttac
    72361 aggtttgaac gtattcacga acccatgact agctttagtt tcggtcacat aataggttcc
    72421 caattccaac gcattagcaa tctcttttgg tgtttccgca tgaccgtttt catccgtggt
    72481 catttcttga acgatttcac cggttggact gtctttgcga atggcaaacg tattaccagc
    72541 taaggaataa ttgtcattcc aaagatcact ccctgtttca actccgcttt tatccagaat
    72601 gatttgccct ttttcccgtg cgttttttga agtcacgtaa atggtttcgc ctgctttaat
    72661 ggtggtagtc atgggggtgg tatcaatcgt ataaggcgcc ggtactgatt tttcggtaat
    72721 ggttactttt gtaccatgag gaatctcatc caatgtagca atgccttctt tgtcagtagt
    72781 cacgtctttt gcaggtaaag tttttccaaa gtctaaatgg aaaaccgttc ctggtacaac
    72841 atcacccgat tctttatcga cttttttgat ctttaaagaa ccctccgttt ccacatcaat
    72901 tttgattgtg taggtattag gtttatcaat cgccccggcc attaaagtct gttggccagc
    72961 ctttttatag gcgacaggtg ttccggtacc agcagatttc ttaagcgtca gcacaccact
    73021 ttcttttgaa ttggcatttg gggtgattat caactgatta ccattcacac gataatcaat
    73081 gtttgcggca ttttccacaa cctcatcgaa ctctgacaaa ttcagattat tcgtatccgt
    73141 cacagtagtc gattgcccta atactgtttt agccgtacta ttatggaagg ttggtttctt
    73201 ctgataatcg tcaatggctt gatttatttt tgcctcaatg gctgcgatat ttacggcact
    73261 accatctgat cgttttattg agtgaagggt atacccatta acttcttgcc agatcatctt
    73321 ctgtgccaca atatgagtat ctgcatctgt acctactttt ttccataaaa cggaaactaa
    73381 tttggcttta tcggacatat ctggtaacgg gtttttctca tagccaggag tgaactcatt
    73441 gtaaatcggg actcctggtt caatacagaa aatatcttgt ttaaagccgt tgtacactgc
    73501 ataatgcgga acagtgactt ctgacattgg acgaccatca ctaaaagttc cttcaacagc
    73561 atattgatgt gctaaatcta gttctacggt taccgtttgt ggatgggtaa tttcatcagc
    73621 aaaagtaatc gtaggagcaa ttgctccaac aattgcttga acagccaaac tcaaaatagt
    73681 taatacacat aatttctttt tttgtttttt atacatgaaa tgttctcctt tcaaattaag
    73741 cacaaaaaaa taagatgctc gcttgaacat ctttgtttat aaagtctttt taaaattttt
    73801 attgactgaa tagaatggat ttgagaatga atgagcctaa aaatttaatc taaaatacga
    73861 aatatactgc ctttaaatta gaacacattt tagaacacaa acatttcaaa tttaatcaaa
    73921 tataataaaa tatatttacg ggaaaacctt tataaatcaa ggtttttcaa acttattcaa
    73981 tgatacgaag aaaaaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg
    74041 ttaattgcga ttatcgttcg agttcacgag ttacgagaat cgtactgggc gaagcaatgc
    74101 tgagcgcagt taccttaatc ctaacttttc tggcactttc cacaatttgg aaagtgcctt
    74161 ttttgtgttt ttagctatgt taataggtag gattcttggt ctataatatc attcgatcta
    74221 taaacaaacg ggaaaaagat aaagtatcat caaacaatat tatttatccg cttctgaggt
    74281 tgtgacagaa gtggtcagct tcaagaaata agaaggaatt tacaaaaatt gcttctcatg
    74341 tttgataaat attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcggaa
    74401 gaagggattg tgaaaagtct tttgtcataa cctcttattt ggtagctaat tgtaaatccc
    74461 aaacggcatg tattattttt cataagtccg tttttaagga ttaatgtttt cttttgcttt
    74521 ttatatggtc tggcttcagc gagaagttcc aacgcatata caaggacgac ttatgtcaac
    74581 gataacaacg attaccatgg tggccagtcc acttggatta gcactgtttg gtgcgctctt
    74641 tgattggaag acaacgcaac cacgtctgcg agacagtcta atttttctgg gagggagtct
    74701 tgctatagtt atccttataa ccggtctggt aaaattactc aagcttgatc tgaaagaagc
    74761 aaaaattttc agtgaagagg aatacagaga aacgactttg gtcgaaaaga aagaatcagg
    74821 aaactgatac aagcgtataa caaactgcct gataatagga aagacacgta ttgtccgatt
    74881 gttttttttg acattcaatt ggaaaattta cactttcttt atacatttct ggctgctttc
    74941 tttatacccg tcaactatac ttcactcatc aataagaaag aaggataagt atggattttg
    75001 gaaatgaaac ggtcttgaaa gcaactggta taaccaaaaa atacggtgct gccaaagcat
    75061 tagataaagt atcaatcgaa atcaaacgtg gaatgatcta tggattgatt ggggaaaatg
    75121 gagcgggtaa gtctaccttt atgagaacta ttatgggttt gatctcgatt gatgaaggtt
    75181 cgatcgaatt atttggaacg acggatttgc aggcagcaag acgacgtatg ggtcaatcga
    75241 ttgaaacccc tgctctttat ccagaattaa ctgcaagaga taacctacgt atccaagcag
    75301 cgaacggcgg tgtgtcggat agagaaatcg aagacctgct gaaaatgatg cgattggaaa
    75361 atacagggaa aaagaaagca aagaatttct ctttaggtat gcgccagcgt ttagctattg
    75421 caaatgcact gatcacgaat ccagaatttt tgattttgga tgaaccgacg aatgggatgg
    75481 atccagcagg gatggcagaa atgcgagaaa tcatccaacg tttggtaaaa gaacggggca
    75541 tcaccgtctt gctttctagc cacttgctag atgaattgtc acagatcgcc actcactatg
    75601 gtattttgca tgaaggacac ttgatcaaag aattatcgaa agaagaattg gcacaagaat
    75661 ctcgtcaatt tataaaaatt gacacttcgg cgacggaaca agcagtaacg gttctcgact
    75721 ctcttggtta tagggattat tttgtacaat ctagccgtgt tatccagctt tttgaaggaa
    75781 ttgaccaagt agcagccatc aatcaagcat tggtagaagc aaaagttcct gtggatggta
    75841 ttcacctagt tgggcaaaaa ctggaagatt atttcttaca attaactgga ggcaatccac
    75901 atgtttaatc tattaactgc tgaaaaaata aaagtatgga agagccgtaa aatgtgggtc
    75961 tcactaggac tgatggtcgt acttccgctt ttttattctt ggaacgaatg gtatatgcat
    76021 acaaaatacg gcaatgaatt aaaccaagca acggatacag tcatcaacgg tgcaacaggg
    76081 attttaatgg tagaaaaaat ggctgcatgg attcttctgg ctttcgcagc atttgcgtgc
    76141 ttttatattg gggaagaatt tcaaaacggt acgattcgca atacgttatc tttaggacgg
    76201 aatcgaatga cttattatgt gtcgaaactt ctcgttacgc ttttgatcac aacacttggc
    76261 gtggttttga tcacgggact agccatgctt gcttacacac ttgctttcgg atttggtgaa
    76321 gttgagggaa tcaaaaacta tggaaattat gttctaaaag tatttcctgt attgcttctg
    76381 ctgacattag ggacattatc tgttccagtg gctttgacat tcatcactag aagtaccagt
    76441 gtcagtttgc ttctttcttt tctttatatc atgggaacgg ccttcattcc cggtgttttc
    76501 gcaaaaatca aaggcttgga atttctaacg gagtggttta cggaaacgtg gctcatgtat
    76561 acggactttg cgcaacaagc aacttattcg caagcaccga aaatgattct ggtcagtcta
    76621 gtaacaatcg tggtatcatc agctctagga atgtttattt tccaaaaatc tgacattaag
    76681 taggtggtcc tgctggaaac tattttgatt atcgaagacg atgaagctgt tcattcctta
    76741 ctggaggagg ttcttgaaca gagatacaaa cttcttgatg cttattcagg tacggaagga
    76801 aaattattgt taagcacata tcctgtcgat ttgatccttc tagatctcat gcttccaggg
    76861 ctttcaggtg aagcattgtt agcagaaatc cgacagacat cgaatgttcc gatcatcgtt
    76921 ctttcagcaa aaagcgatca aagagataaa gtttccttgt tggcagcagg agcggatgac
    76981 tatgtgacga aaccatttga tatcgaagaa cttttgttac gaatcggcat ccaacttcgt
    77041 catcagactt ctgtccaagt aaaagatctg tcgcaacgca tctattacaa ggaaatctta
    77101 ctggacaaag agtcgaggga tgtaaatgtg aatggtgtgg ctgtccattt gacaggaaga
    77161 gaattcgatc tgctgaagct ttttttagaa catccgaaaa aagtattttc gcgagcaaat
    77221 ctttatgaaa cagtttggca agaaccatat tttgatagtg agaaaacagt gaatatgcat
    77281 atttccaatc ttcgagggaa gctagcaaag gcacatgctg tgtatattca tacggtgtgg
    77341 ggagtggggt ttagatttga ttaaatggct gttgcttctc gttgttatct ttatgggaag
    77401 ttttattttc ttcctgcaaa gggaaatcaa gagattaact aagaaaatcg ccactctttc
    77461 tgaacgacaa gaatatggtg gtcgtctttc agtcgaattt cgagaaaaga atctaatgga
    77521 cctagtagat gcactgaata catggttgga tgaaaatgaa caaaaaggac aagcatttca
    77581 agaaatggaa gaaaacatca gactatcgat cgtcggcctt tctcatgatc tcagaactcc
    77641 tttgactgct attaacggtt atgtacaatt actggaacag gtagaggata cggagaaacg
    77701 ggagaagtat ttaacgatca tcaaacaatc tgttgcaaga ttactcagta tgacggatca
    77761 gttttatgat cttgctcgaa tagagacgaa gcaaaaagaa atggatctcc atacgctttc
    77821 tttttctaaa gaggtggaag aagtattttt ctctttttat gaacaatttt ctgagaaaaa
    77881 tatcgaggta gcgttcgctg aacactcgat aaatacaact gtattagcag atccgctcat
    77941 gttgctgcga gtgctgcaaa atatcataca gaatttattg cgttatgcag atggacaagc
    78001 aaaggtgaca ttttcaaaag aggatccatt cattcgatta acagtggcca atcctatcaa
    78061 accaggaacg caaacctctg ttgaaaaagt cttccagcgt ttttataccg aaaataccag
    78121 ccgcacaaat acggaatcta gcggaatcgg gctttacctg tcaaaaaaat tggtggaagg
    78181 aatgggagga gagatgaccg ctagattaga cgggggcatc ttctccatct ccgtcaagtt
    78241 gcggagggtt taattataca agattagtga gaactagtag aaaaatgtat tatcttatat
    78301 atatttaata gagaaaaaag cctgtgatat aaatattgca ggctttttta ttgatttgaa
    78361 ataatcaaga atattagaaa cttctacatt aatcaagaac tttcttctgt atgaaaatag
    78421 agataataat tgtacactta agctgtattc aggaggtgaa gataatgggc atcgaattta
    78481 gcgaacggca aatgaaaata ctatactttt tgattgaaaa tgagcacaca acttacaaag
    78541 aattatcaga acaattatat gtatctacga aaacaattag caaagatatt ttaattttga
    78601 aagaaataat ccaaaaaatg ccagatgtac aaatgttggt tcaacctaaa aaaggcgttt
    78661 cgcttattgg aaaaaaagaa acacttcgaa atttattatc cagtcataaa atcaatatcg
    78721 cagactctcc ggaggaccgt ctaacttatg tgtttgctaa attattgaat actaatgatt
    78781 ctctaaagat tcaaaatctt gctgacgaat tatacgtgag caggtcgacg gtagaaagca
    78841 caatgaaaga tgttagaaaa agactaaaca agcatgggat gtccttagtt tcagatcgaa
    78901 atggcgtgcg catcaaagct gatgaaaaaa gtaaaagaag gttgatgtca gaagttgtga
    78961 actattattg gggtggcttt acagcatcta acagtaaaac agatctctta gacttgaata
    79021 tcaatttcat tggtgaagcg aataatttct taaataagga catattgaaa aaagtagccg
    79081 aattgcttaa tcgatacatg aataagacac aattgaaatt tacagattat gaatttcaaa
    79141 ctttagctat ccaccttgct attgcgatag aaaggattga aacaagcaat ttcttatcac
    79201 gtagtaataa ttctgaagaa gaaatctcaa agaatacact tattttaatc aaaatgattg
    79261 aaaaagcatt ttcaattatt gtgccaatag atgaacaagc ttatgttgac attcacatta
    79321 cttcgattga aaaaaatgct atgaatcacg acttagatca aacgaagctt tcctatttag
    79381 atatgggtgt tgagctacaa gagttagtaa gaattaaatt aaatgaattt tatcctgatg
    79441 aagaattgat caataatcta gtattacatc tcaatgcagc agttaaaaga ctcaaattgg
    79501 gagtaaatat ctataaccct tatacggaca aaatcaaata ttcttttaaa aggtcattta
    79561 tgataagtgt agatttatta gaggaaatcg aagagagatt ctgtatacat tttaatgaag
    79621 atgaaatcgc ttacgtaaca ctccatattc aatcactttt ggatcgttac aaacctgaca
    79681 aaacgaaagt gatattagtt tgtagtagcg gatatggaac atcaaaatta ttagagcaaa
    79741 gaataaataa cggttttgca gatatggttg agatagaaga tgtactaagc atcaatgaac
    79801 tacaagatag aaaagtcact gatgaacttg ttataagcac gattccgatt gaaaatacaa
    79861 attttcctgt tattgttgtt agtcctttga tgttaggggc agatgtcaga aaagtaaaac
    79921 agtatctaca gttaaatgaa caaacagaag atgcttttct aaatttatta gataaacgat
    79981 tttgcttttt tacccaccaa ataaaggata atcaagtgaa cgttttaaat ataattacca
    80041 aaaaattggt aaaagaaaat tacgcgaaag aagggatact agagggagca atcaaaagag
    80101 aaaaactatc ttcaacagcg atgaatgatt ttgctatgcc gcatatcgaa gtagatttta
    80161 taaaaaagcc agtaatctgt gtctacgtta atccagaagg aattgattg
//
LOCUS       DAZKNV010000005        77849 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000005 DAZKNV010000000
VERSION     DAZKNV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.005"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            50..1192
                     /locus_tag="ACG8M1_000349"
     CDS             50..1192
                     /locus_tag="ACG8M1_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0421095.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(1290..2681)
                     /gene="sufB"
                     /locus_tag="ACG8M1_000350"
     CDS             complement(1290..2681)
                     /gene="sufB"
                     /locus_tag="ACG8M1_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFQ0421096.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(2686..3156)
                     /gene="sufU"
                     /locus_tag="ACG8M1_000351"
     CDS             complement(2686..3156)
                     /gene="sufU"
                     /locus_tag="ACG8M1_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFQ0421097.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(3143..4378)
                     /locus_tag="ACG8M1_000352"
     CDS             complement(3143..4378)
                     /locus_tag="ACG8M1_000352"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFQ0421098.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(4375..5661)
                     /gene="sufD"
                     /locus_tag="ACG8M1_000353"
     CDS             complement(4375..5661)
                     /gene="sufD"
                     /locus_tag="ACG8M1_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFQ0421099.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(5674..6447)
                     /gene="sufC"
                     /locus_tag="ACG8M1_000354"
     CDS             complement(5674..6447)
                     /gene="sufC"
                     /locus_tag="ACG8M1_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFQ0421100.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(6644..7492)
                     /locus_tag="ACG8M1_000355"
     CDS             complement(6644..7492)
                     /locus_tag="ACG8M1_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0421101.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(7516..8202)
                     /locus_tag="ACG8M1_000356"
     CDS             complement(7516..8202)
                     /locus_tag="ACG8M1_000356"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFQ0421102.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(8195..9229)
                     /locus_tag="ACG8M1_000357"
     CDS             complement(8195..9229)
                     /locus_tag="ACG8M1_000357"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421103.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(9292..9548)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(9624..9962)
                     /locus_tag="ACG8M1_000358"
     CDS             complement(9624..9962)
                     /locus_tag="ACG8M1_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFQ0421104.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(9964..10320)
                     /locus_tag="ACG8M1_000359"
     CDS             complement(9964..10320)
                     /locus_tag="ACG8M1_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFQ0421105.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(10326..11513)
                     /locus_tag="ACG8M1_000360"
     CDS             complement(10326..11513)
                     /locus_tag="ACG8M1_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0421106.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(11704..12549)
                     /locus_tag="ACG8M1_000361"
     CDS             complement(11704..12549)
                     /locus_tag="ACG8M1_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0421107.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            12783..13748
                     /locus_tag="ACG8M1_000362"
     CDS             12783..13748
                     /locus_tag="ACG8M1_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFQ0421108.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            14125..15168
                     /locus_tag="ACG8M1_000363"
     CDS             14125..15168
                     /locus_tag="ACG8M1_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFQ0421109.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(15230..15694)
                     /locus_tag="ACG8M1_000364"
     CDS             complement(15230..15694)
                     /locus_tag="ACG8M1_000364"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFQ0421110.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            15940..16887
                     /locus_tag="ACG8M1_000365"
     CDS             15940..16887
                     /locus_tag="ACG8M1_000365"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0421111.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(17098..19170)
                     /locus_tag="ACG8M1_000366"
     CDS             complement(17098..19170)
                     /locus_tag="ACG8M1_000366"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0421112.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(19103..19480)
                     /locus_tag="ACG8M1_000367"
     CDS             complement(19103..19480)
                     /locus_tag="ACG8M1_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFQ0421113.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(19609..20169)
                     /locus_tag="ACG8M1_000368"
     CDS             complement(19609..20169)
                     /locus_tag="ACG8M1_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0421114.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            20319..21611
                     /locus_tag="ACG8M1_000369"
     CDS             20319..21611
                     /locus_tag="ACG8M1_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFQ0421115.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(21671..22789)
                     /locus_tag="ACG8M1_000370"
     CDS             complement(21671..22789)
                     /locus_tag="ACG8M1_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFQ0421116.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(22803..24224)
                     /gene="arcD"
                     /locus_tag="ACG8M1_000371"
     CDS             complement(22803..24224)
                     /gene="arcD"
                     /locus_tag="ACG8M1_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFQ0421117.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(24470..25591)
                     /gene="mnmA"
                     /locus_tag="ACG8M1_000372"
     CDS             complement(24470..25591)
                     /gene="mnmA"
                     /locus_tag="ACG8M1_000372"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFQ0421118.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            25995..26594
                     /locus_tag="ACG8M1_000373"
     CDS             25995..26594
                     /locus_tag="ACG8M1_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0421119.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(26732..28018)
                     /gene="efmA"
                     /locus_tag="ACG8M1_000374"
     CDS             complement(26732..28018)
                     /gene="efmA"
                     /locus_tag="ACG8M1_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFQ0421120.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(28289..28633)
                     /locus_tag="ACG8M1_000375"
     CDS             complement(28289..28633)
                     /locus_tag="ACG8M1_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFQ0421121.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(28770..29915)
                     /locus_tag="ACG8M1_000376"
     CDS             complement(28770..29915)
                     /locus_tag="ACG8M1_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFQ0421122.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(30095..31069)
                     /locus_tag="ACG8M1_000377"
     CDS             complement(30095..31069)
                     /locus_tag="ACG8M1_000377"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFQ0421123.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(31149..32024)
                     /locus_tag="ACG8M1_000378"
     CDS             complement(31149..32024)
                     /locus_tag="ACG8M1_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFQ0421124.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            32154..34061
                     /locus_tag="ACG8M1_000379"
     CDS             32154..34061
                     /locus_tag="ACG8M1_000379"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFQ0421125.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(34602..37880)
                     /locus_tag="ACG8M1_000380"
     CDS             complement(34602..37880)
                     /locus_tag="ACG8M1_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFQ0421126.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(38151..38696)
                     /locus_tag="ACG8M1_000381"
     CDS             complement(38151..38696)
                     /locus_tag="ACG8M1_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFQ0421127.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(38708..39400)
                     /locus_tag="ACG8M1_000382"
     CDS             complement(38708..39400)
                     /locus_tag="ACG8M1_000382"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFQ0421128.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(39419..39703)
                     /gene="macP"
                     /locus_tag="ACG8M1_000383"
     CDS             complement(39419..39703)
                     /gene="macP"
                     /locus_tag="ACG8M1_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFQ0421129.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(39716..40279)
                     /locus_tag="ACG8M1_000384"
     CDS             complement(39716..40279)
                     /locus_tag="ACG8M1_000384"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFQ0421130.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            40507..41169
                     /locus_tag="ACG8M1_000385"
     CDS             40507..41169
                     /locus_tag="ACG8M1_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFQ0421131.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            41293..42489
                     /locus_tag="ACG8M1_000386"
     CDS             41293..42489
                     /locus_tag="ACG8M1_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFQ0421132.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(42590..43966)
                     /locus_tag="ACG8M1_000387"
     CDS             complement(42590..43966)
                     /locus_tag="ACG8M1_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0421133.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(44003..44869)
                     /locus_tag="ACG8M1_000388"
     CDS             complement(44003..44869)
                     /locus_tag="ACG8M1_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFQ0421134.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(44958..45983)
                     /locus_tag="ACG8M1_000389"
     CDS             complement(44958..45983)
                     /locus_tag="ACG8M1_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0421135.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(46001..46675)
                     /locus_tag="ACG8M1_000390"
     CDS             complement(46001..46675)
                     /locus_tag="ACG8M1_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0421136.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(46859..47752)
                     /locus_tag="ACG8M1_000391"
     CDS             complement(46859..47752)
                     /locus_tag="ACG8M1_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0421137.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(47826..49523)
                     /locus_tag="ACG8M1_000392"
     CDS             complement(47826..49523)
                     /locus_tag="ACG8M1_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0421138.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(49516..50829)
                     /locus_tag="ACG8M1_000393"
     CDS             complement(49516..50829)
                     /locus_tag="ACG8M1_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFQ0421139.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(50829..54770)
                     /locus_tag="ACG8M1_000394"
     CDS             complement(50829..54770)
                     /locus_tag="ACG8M1_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0421140.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(54879..55337)
                     /locus_tag="ACG8M1_000395"
     CDS             complement(54879..55337)
                     /locus_tag="ACG8M1_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0421141.1"
                     /translation="MKGLKLKILQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(55635..56153)
                     /locus_tag="ACG8M1_000396"
     CDS             complement(55635..56153)
                     /locus_tag="ACG8M1_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFQ0421142.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(56155..56772)
                     /locus_tag="ACG8M1_000397"
     CDS             complement(56155..56772)
                     /locus_tag="ACG8M1_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFQ0421143.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(56769..57557)
                     /locus_tag="ACG8M1_000398"
     CDS             complement(56769..57557)
                     /locus_tag="ACG8M1_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0421144.1"
                     /translation="MTVIGIILIIPLLWMVFTSLKPMEEIVRYPPTFFPEKIVWENYL
                     DTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYGFAKLDFPGKKLMFALVLSTMMI
                     PGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFNIFLMRQFYLSINNELIEAAEID
                     GANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFLGPLLYIQDQEKYTLQIGLQVFQ
                     NQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGMDLTGGSKG"
     gene            complement(57619..58530)
                     /locus_tag="ACG8M1_000399"
     CDS             complement(57619..58530)
                     /locus_tag="ACG8M1_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0421145.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(58571..59905)
                     /locus_tag="ACG8M1_000400"
     CDS             complement(58571..59905)
                     /locus_tag="ACG8M1_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0421146.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            60113..60943
                     /locus_tag="ACG8M1_000401"
     CDS             60113..60943
                     /locus_tag="ACG8M1_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFQ0421147.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(61187..61436)
                     /locus_tag="ACG8M1_000402"
                     /pseudo
     CDS             complement(61187..61436)
                     /locus_tag="ACG8M1_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(61627..61821)
                     /locus_tag="ACG8M1_000403"
     CDS             complement(61627..61821)
                     /locus_tag="ACG8M1_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421148.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(62326..62511)
                     /locus_tag="ACG8M1_000404"
     CDS             complement(62326..62511)
                     /locus_tag="ACG8M1_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421149.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(63361..63702)
                     /locus_tag="ACG8M1_000405"
     CDS             complement(63361..63702)
                     /locus_tag="ACG8M1_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0421150.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(63702..63932)
                     /locus_tag="ACG8M1_000406"
     CDS             complement(63702..63932)
                     /locus_tag="ACG8M1_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0421151.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            64219..64557
                     /locus_tag="ACG8M1_000407"
     CDS             64219..64557
                     /locus_tag="ACG8M1_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421152.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(64762..65324)
                     /locus_tag="ACG8M1_000408"
                     /pseudo
     CDS             complement(64762..65324)
                     /locus_tag="ACG8M1_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(66056..66637)
                     /locus_tag="ACG8M1_000409"
     CDS             complement(66056..66637)
                     /locus_tag="ACG8M1_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0421153.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(66820..67446)
                     /locus_tag="ACG8M1_000410"
     CDS             complement(66820..67446)
                     /locus_tag="ACG8M1_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFQ0421154.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(67468..68799)
                     /locus_tag="ACG8M1_000411"
     CDS             complement(67468..68799)
                     /locus_tag="ACG8M1_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFQ0421155.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(68954..69355)
                     /locus_tag="ACG8M1_000412"
     CDS             complement(68954..69355)
                     /locus_tag="ACG8M1_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFQ0421156.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(69441..69647)
                     /locus_tag="ACG8M1_000413"
     CDS             complement(69441..69647)
                     /locus_tag="ACG8M1_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421157.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(69742..71244)
                     /locus_tag="ACG8M1_000414"
     CDS             complement(69742..71244)
                     /locus_tag="ACG8M1_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFQ0421158.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(71262..71717)
                     /gene="argR"
                     /locus_tag="ACG8M1_000415"
     CDS             complement(71262..71717)
                     /gene="argR"
                     /locus_tag="ACG8M1_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0421159.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(71815..72432)
                     /locus_tag="ACG8M1_000416"
     CDS             complement(71815..72432)
                     /locus_tag="ACG8M1_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0421160.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            72653..74026
                     /locus_tag="ACG8M1_000417"
     CDS             72653..74026
                     /locus_tag="ACG8M1_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0421161.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            74101..75213
                     /locus_tag="ACG8M1_000418"
     CDS             74101..75213
                     /locus_tag="ACG8M1_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0421162.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(75285..76922)
                     /locus_tag="ACG8M1_000419"
     CDS             complement(75285..76922)
                     /locus_tag="ACG8M1_000419"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFQ0421163.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(77090..77698)
                     /locus_tag="ACG8M1_000420"
     CDS             complement(77090..77698)
                     /locus_tag="ACG8M1_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0421164.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT        22046 a        16528 c        13903 g        25372 t
ORIGIN      
        1 tcttcaaata acttctctac ctgcaataat gaagtaagga gagaatcaaa tggcaacatt
       61 ttttagttat aaattacaaa atggcgaaaa atattgggga tttgaaactt atttagggaa
      121 agatcccaag actggaaaag atatacgtac aaagcgtaga agattcaaat caaaagctga
      181 ggcgcaaaca gcacttaata gactacttgt agactttaaa gaaaaacaag agtttaaaat
      241 caatgttaca acttttcaag agttgtatga attatggatt gataactaca gaacaagagt
      301 aaaaccgtct tctgttgccg ttgctcaacg tttttgcaaa aaccatatat tacctgcttt
      361 tggggaatta cgattggata aaataagtgt tagctattgc caaaaacagg tgaatgaatg
      421 gcacaaaaca ttaaaacaat atggtttctt gagaaaaaca actgctcaaa tatttaaatt
      481 tggagtagca atggaagtct gtaaggataa tcctatgtct aaaacattgc ttccaagaaa
      541 aattgaagaa gaacaaccct tgaagtttta cacgaaagat caattacaac tgtttttaca
      601 gaatactaaa gaaaataatt cagttaaact gtacactttt ttccgtttat tagcttatac
      661 aggaatgcgt aaaagcgaag cattggcgct tcaatgggaa gatatagact atttcaataa
      721 aacaataaca attggtaaaa ctatcgctca agacgagttt aatcaagtag ttctacaagt
      781 acctaaaact aaaaattcat caagaacgat tcagcttgat gattttacac ttaaacaact
      841 gcgtatttgg caacaagaac aaatgaaaat aatgatctta tatggctata acacgaattc
      901 accaaaacag tttcttttca ctacaaacac aaacaagttg tactaccccc aagtagtaaa
      961 cgattggtta gactggattt acaaaaagac accgatggag cctcaaatta ctccacatgg
     1021 atttaggcat acccactgta gcttattgtt tgaaagtggt gcgtcgataa aagaagtaca
     1081 ggaacgatta ggtcataaag atattaaaac taccatgaat atctatgctc atgtcacacc
     1141 acaatctgtt aagaaaactg gtgaccgatt tgcaaaattt atgggcgaat aattccaaac
     1201 gtagccaaaa acgtagccaa ccattaaaat acaaataaaa aaacgctcga aacgctttaa
     1261 tatcaacgtt tcgagcaatg aaatagttat taacctacag acccttccat ctcataactg
     1321 atcaatcgat tgagttcgac tgcatattcc attggaagtt ctttggtgaa tggttcaaca
     1381 aagcccatga cgatcatttc agttgcttca gattcggtca ggcctcggct catcagatag
     1441 tagagttgtt cttctgagat ttttgagact ttggcttcgt gttctaaaga gacttggctg
     1501 ttgtggatct cattgaatgg gatcgtatcg gatttcgacc attcgtccat gatgatcgtg
     1561 tcacattcga tatgagagat cgaacccgca ctgtttttgg caaaggttac ttgtcctcga
     1621 tagtttactt ctccgccgtc ttttgaaatt gatttagaga cgatagagct agatgtattt
     1681 ggtgcattgt ggatcatttt tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg
     1741 atggagagca tggtgcctcg tgcacctttt ccatctaagt aaacacttgg gtatttcatc
     1801 gttgtttttg cacctaggtt tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt
     1861 gctcgtttgg ttactaagtt gtacacattg tctgaccagt tttggatcgt tgtgtaacgg
     1921 caatacgcat cttttcttgt aaagatttct acgatggcgg catgcaggct gttacttgaa
     1981 taagtaggtg ccgtacaacc ttcgacatag tggatgcttg ctccttcgtc aacaatgatc
     2041 agcgtacgtt cgaattgccc cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga
     2101 acatcgactt tgacgccttt tggcacgtaa ataaaggtcc cacctgacca tacggctgaa
     2161 ttcagcgctg ctaatttgtt gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat
     2221 aattcagggt attctttcaa agcagagtca gtgtcagtaa agacgattcc taacttttcg
     2281 aattcatctt tcatattatg gtacacgact tctgattcat attgtgcgga agcaccggct
     2341 agataagctc gttcagcttc tggtatacca atcttttcaa atgtatcttt gattttttct
     2401 ggtacgtctt cccagtcacg agcgggtttg tcacttggtt tttggtaata tttgatggca
     2461 tcgaaatcga tgtctgaaag gtcggggccc catgtttgca ttggcatttt gttaaatgtt
     2521 tctagagatt tcagacggaa ttcaagcatc cattctggtt cgcctttgat tcttgacatc
     2581 tcacggatca cttcttctgt caagccttct cctgtactga aaaccggttc gacatcatcg
     2641 tgaaacccga atttatattc ttctaattct ggtacgccca tgttctcact cctcttcctt
     2701 gtggtaatga tggaaagctg cggtaccatc gttttccatt gcttttccta gtgctttcca
     2761 ggcaagtgtc gcacatttga tccgagcggg aaatttagct acaccaccaa gcatagcagc
     2821 atcgcctaat tggtcgggat ctttgacttc ttttccttgg acaagctgta gaaagtctac
     2881 agttaaatgt tctgcttctt ctattgattt tccgatgacg gcgtctgtca tcatcgaggc
     2941 acttgccgta ctgatggagc agccactgcc gtcaaaggcg atatttttga tgattccgtc
     3001 ttttacatcg acttgcaatt cgatcacatc tccacatgtg gggttgttca attcgatctt
     3061 gcttgtcgag tcagtcaagc ttccacgatg atgcggatgg gaagaatgat ccaagatcac
     3121 ttgacggtat aaattgtcta atttagatag tcccatgttg gaaaaactcc tttgttgcca
     3181 tgattgcttc aactaaacgg tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc
     3241 gagcagtcgc tgatacttca aggtacttca atagcggttg cgcacaatga tgacctgctc
     3301 tgacggctac cccttccatg tctaaagctg tcgcgacatc atggggatgt aacccatcca
     3361 aattgaatgc aacgactcct gtccgaaaat tcgggtcttg tggaccataa acagtcaatc
     3421 catcaattgc ttgtaatttt ggcaacacat aagcggctag ttcttcttca tatcgatgga
     3481 tattgtccat accgagtttt tgcaaataat cgattgcatg gcctaatgcg atagcgccgg
     3541 cgatatttgg tgtccctgct tcgaatttcc aaggtagttc tttccatgta ctgtcgtata
     3601 attcgacaaa atcgatcatt tcgccaccaa attcaacagg ttccatttct tctaaccatt
     3661 ttcgtttacc atataaaaca ccaatacctg ttggtccgca cattttgtgt ccgctgaaag
     3721 caaagaaatc acagtctagt gcttggacat caatggccat gtgcggggca gattgagcac
     3781 catctactac gatgaccccg ccgttttcat ggacaagttc agctaattct tgaacaggat
     3841 tgaagacacc taagacattg gatacatgag caatggagac gattttggtt ttgtccgtaa
     3901 tctttttcgc tgcatcctcc atatccagga agccttcttc tgttagttcg atatatttca
     3961 agacagcacc tgttcgtttt gccaactgct gccacgggat aacattagaa tgatgttcca
     4021 tgtaagagag cactatctcg tctcctgctt tgatatagcg gtcgccgaag gttctggcta
     4081 cccaattcaa gcttgtcgtc gtaccacgag taaacagcac ttctgctgtt tcttttgcat
     4141 ggatgaacgc ccgtactttt tctcttgctt gttcataatc atgggtcgcg cgttctgcta
     4201 acgtatggac accgcgatga acattggcgt tatcgtgttc gtaatagtac gctaatgcct
     4261 ggagtacttg ttttggcttt tgggtcgtcg ctgcattatc cagataaact aaaggttcat
     4321 cattgacgtc ttgaaataag ataggaaaat cattgcgtag ctttttagca tcgatcatcc
     4381 attcaacttc ccttcgatta cttcgactaa ttctttccga acttgttcta cagggattgc
     4441 tgttaagaca gaaccgagga atcctcgaat cactaagcgc tctgcttctt ctttatgcaa
     4501 tcctctactc atcagatagt acatttcttc tggatcaact cgtcctacac tggcagcatg
     4561 tccagcagtt acttcgtttt catcgatcaa aagaatagga ttcgcatcac cacgtgcttt
     4621 atcagaaagc atcaagacac gactttcttg ttgggcatct gcaccttttg cccctttcaa
     4681 gatgtggccg ataccattaa aggtcaatgt tcctttttct cggatcactc cgtgttgcaa
     4741 aatatgcccg atcgtatgag gggctttatt ggttactcgt gtatcgattc cttggatttg
     4801 tctgcccgag ctgattgcca cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc
     4861 tgagtcaaag tcagcgatca catgaccgtc attcatgaca ccaattgccc agtcgacaga
     4921 agcatctcgt aaaatgtgcc cacggcgatt catataagaa gtaatatttt ctcctaattg
     4981 atctacggct gaatatttga tttttgaacc agctttagcg atgacttcca cgatgatatt
     5041 acctgatgat tttgctactt gttctttggt tgtctggaaa cgttccagat aagaaaattc
     5101 actatgttca tctgccacga tcaacacatg cttgaagaag tgctcatcgg atgcgccatc
     5161 ttgaatgaat aaggactcga gtggttcatc gatcacgaca tttttaggca catacaggaa
     5221 aataccgctg ttcataaaag ctacatggag tgcagtcaat tggtcttcgt tcatgtttac
     5281 tgcttttttc atataatatt cttggactag ttctggatat tcgatcattg cagtgaacaa
     5341 gtcggtaaaa atgactcctt tttctgctaa ttccacaggc agttgttcaa aaatcgtcca
     5401 tgaaccttgt tggacaagca caggattgtc tttcattgca tcaaatgccg gaatcgtgcc
     5461 tgtttcactg atggtttgtg tttctttcac atcaaataac gaccagcgat ggaatttcac
     5521 ccgatcgata tgcggcaatg gcagttcatc tgctttcgct agtgcgtctt gacggaaggt
     5581 tctcatccaa tcaggttcgc ctttacttaa agaaaaatca tttaccgcgt caagataatc
     5641 gagccagttt ttttctttca ttcttgctcc cccttacgct tcttcttctt tatagtcgat
     5701 tcctaattct ttactgatac cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc
     5761 attccctgtc atgactactc ggccttccat catgatgtga acgacatcag gtgtgatata
     5821 gttcaataat cgttgatagt gggtgatgat caatgcaccg aaattgtctc cgcgcatttc
     5881 atttactcct ttagcaacga ctttcaaagc atcgatatcc agacctgaat cgatttcgtc
     5941 taaaattgca aatgtaggtt ctaacatcaa caattgcagg atctcattcc gtttcttttc
     6001 tccgccagaa aaaccttcgt tcagataacg ttcagccatt tcttctggca tatttagtaa
     6061 agccattttt tcatctaact ttttcaaaaa tgccataaca gaaattttgt cgttttcatc
     6121 acgtttcgca ttgatcgctg cacgcatgaa ttccgcattc gtgatacctg gtatctcact
     6181 tggatattgc atagctaaaa ataagccaag tcgcgcacgt tcatctactt ccaagtctaa
     6241 aacatttttc ccgtcaaaca aaatttcgcc ttctgttact tcatagtttg gattgcccat
     6301 gatagcggca gataaggtag attttcctgt gccgttaggt cccatgatgg catggatttc
     6361 tccggttttc attgttaggt ttacgccttt aaggatttct ttttcctcga tcgacacatg
     6421 tagatttttt atttctaaga cagacatgca ttataccccc aaattctctt tcgttctcac
     6481 tcattttaga ctaattgaga atgaagcgca atgaccttcc ttactaaaat caaatatctt
     6541 ttatttatta ttaaacaatt ttgatttcta aattagaata ggtataaaaa agatgagaaa
     6601 taagccatta cagacttatt tctcatcttt tttgttccat accttatttt gcatcagcct
     6661 ttactggttt aacagagccg ccccatttgt ctgtgatcca ttcttggact tctttgcggt
     6721 gaagcacttc aatcagtttt ttgattttgt cactgtcttc atcaccttta cgagtcgcaa
     6781 taatattcac gtaaggagag ttgtcctttt caagcaatac ggcatcttct aatggattca
     6841 accctgcgcc gtaagcgaag tttgcgttga ttgcaactag gtcaccttca tcattttggt
     6901 acgtagaagc taaaagtgat gggtcgatcg tatggttgaa cttcaagttc ttagggtttt
     6961 cttcaatatc atcgaatgtt gctgtttcca gatctactcc atctttgact ttgactaagc
     7021 cagcatcttg tagaattgtg atgatgcgtc cccagtctga ttcagaattt gaagtaatga
     7081 ttgttgcacc atcttttaat tcggaaacat ctttgacttt tttagagtac aagcccattg
     7141 gttcgatgtg gacagcaccg gcattgacaa agtcatatcc tttttctttg atttctttgt
     7201 tcaaataagg aatatgctgg aagtaattgg catcaatgtc gccttcttcc aaagattggt
     7261 tcggtaatac atagtcatcg aatttgacga tttcaagatc gattccttca tctttcaata
     7321 atggtttcac atgttccaaa atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg
     7381 tcgtgtcgtc tgctttattt gctgaatctt tgctgtcgct gttgttaccg catgctgcta
     7441 atcctacagt cagcaaaagc gctgctgcaa atccaaaaat tttctttttc atatcctaca
     7501 tccccctata tcctattatc ttttgtctgt tttcttagtt aagaaatcac cgattccttg
     7561 aacgataaat acgattagta aaataattaa agtcgcaacg aatgtcactg ttagattacc
     7621 acgctggtag ccttcctgcc aagcaagacc tccaagtcca cctgcgccga tcgcgccggc
     7681 catcgcagta aatccgatca tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg
     7741 aatactttca ggtatcaaga ccttccagat gatttcccag taacttgctc ccattgcatc
     7801 tgctgcttcc agtacaccag ggctgacttc acgaaaagca atctctacta gacgggcata
     7861 aaatggtgct gcggataaaa caagagctgg aatggctgct tgcgcaccta gcatagtgcc
     7921 tacgattgct ttagtaaatg gaatgatcaa aaccatcagg atcataaatg gcgttgaccg
     7981 gaaaatatta ctgatgatcg atacgattcc ataaatgatt cgagcatacg gtttgttttt
     8041 gcgtccaata gagtaaagga tcaatcccaa aactaatccg atgatcgtca ctaagaccat
     8101 tgagattaat gtcatatata gtgtatcaag gatagcctga ttcatcgttt ccgggttgat
     8161 ttgtttaaaa tctagatatg tttctgaaaa gcttttatcc acgatggatc acctcaattc
     8221 ctactccttg ttctttgatg aacacttctg cttgatctaa ttctttggtt tcaccagtca
     8281 tcaagacagt caatgaacca aaggaacctt ctttcacttg tttgatcttt ccatacacaa
     8341 cgttgacatc gatgttatag cgtcgaatcg cttgggaaat gactggctcg ttggcatttc
     8401 tttcgctaaa ggtcaaagtt gccaaacggc cgcttggatt ttctttgatg agttcagcta
     8461 atagttctgt cgaatcagct tctggttcga tgtcttgttg tacaaagcgt ttggttactt
     8521 cttttttcgg ttgtctgaag acagtcaata cgtctccttc ttctacgact ttccccaact
     8581 ccatcacagc gactttgttg cagattttgc ggatcacatt catttcatgt gtgatcaaga
     8641 cgatggtcaa attcaatttc ttattgatcg ctaacaataa gtctaatact tcttctgttg
     8701 tttgcgggtc caatgcgcta gtagcctcat cacaaagcag gatctcagga tcatttgcca
     8761 atgctcgtgc gataccgacg cgttgtttct gtccgccgga aagttgtgaa ggatatgctt
     8821 gtccgcgtcc ttctaacccg actaaacgca acagttcttc tgcccgttct ttacgtttgc
     8881 tctttggtac gccagctaat tccagcggca gctggatatt ttcaagtaca gttcttgacc
     8941 ataacaggtt gaaatgctgg aagatcatac cgattttctt tcggaatgta cgtaattctt
     9001 tgttttttaa ttttgtaata tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct
     9061 caagtccatt caggagacgg actaatgtac tttttcctgc gccagaatag ccgacgattc
     9121 cataaatatc ccctttttca acgtttagtg aaacgtcatt gacggcttgg atgtttccgt
     9181 ttttcccatt gaatgtcttt ttgacattcg ttagttggat taatgacatg ccattcacat
     9241 ctttctctta taatttttca aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac
     9301 gaaagcttga acttccgtgt taccaccttg atttaccgtt acttcgcaat aacagcctct
     9361 tccagtactt ggacttagct tctttccgta tactgtcgcg ctgtaacggg cactcccgta
     9421 gtaagtttgc ttacgctcgc ttactctgct ctaagaccat cttccatctc attttcgtta
     9481 cccattttca gcaaacaggg ctctcttcaa acgtccgtga catgtactct tcttttcaaa
     9541 gctttctcgt ttcatatagg attgcttatg attatagcaa ctggaagaat cagtgtcaac
     9601 ttttttcaag tgattttctg attttataat tcgtcaaatt cttttggatc aacatctttg
     9661 aaacttaaga tccacgcatt catttcatct gaatcattca agatattgat atcttcaccg
     9721 attttatcat taacagaaga aactgtaccc gttagcgggc tggcaaattc attgaccgct
     9781 ttttccgctt caacttcgat cagaggttca tcttttttta gcgattgtcc tgcttttggc
     9841 agattggcaa acgtgatgtc tccaagttct tcttgcgctt catttgtcaa accaacacag
     9901 tattcttttc cattaaataa gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc
     9961 attttatatc agttctcctt cataaatttt ttcattgaat ccaattgcaa caagctggtc
    10021 ctctcgtaag atcagtggtc gcttgatcag cataccatct gtcgataaga cttggctcgc
    10081 ttttgaagcc gtaaactcgc ctacttgatc tttcagtcca agttcccgat atttcatccc
    10141 gcttgtgttg aacaggcgac ggattggtac ttgactcgtt tctagccaag tctcaatcgt
    10201 tgaggccttc ggtacttctt tgatcatatc aacggtttga taactaacgc catgctggtc
    10261 taaccacgct ttggcttttt tgcatgttga acatttcggg taccagtaaa aggtgtacaa
    10321 ttttcttacc tccttgaaga tcttgcaggt gcttcatttt ggtatctcat cgataatatc
    10381 aacccgatac cgatcatgtt ccctaaaatc gaggatcctc cctgactaat gaaaggcaat
    10441 gggatccctg ttaaaggaag taatccgata tttgctccaa tattctcaaa gacatggaac
    10501 agcagcatca tgatcaaacc gcttgcgata taggcgtaaa attcattatt cgtatcgaaa
    10561 cacacccgaa tcatacgata gattaaaata aaatacaaga aaatgacgaa tgcaccaccg
    10621 ataaagccga agttttcacc gataacggta aaaatcatat cggactcacg aacaggcaca
    10681 tagatattgc ttacgttgaa tcctttacca aacaagccac cggtaccaat tgccaaaagt
    10741 ccttgggccg gctgataact cattcctgac gtatcatgga aagggtccag ccatgaatca
    10801 atacgtgcaa actgataaga tttgaatcca actttataaa gcaagtctct tccgccttca
    10861 gtcgtaacca agaagatcgt tcctgctcca acgactactg ccaagattac tacaggtgcg
    10921 atgatgcgcc aagagattcc agacatcagg aaaatcccgc caaagatcgc aagaaagaca
    10981 agcatcgttc caaagtcatc ttgggccatg atcaatgcta aaaccggtat tgtcacgatc
    11041 aagagcttcc caatcagcca aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta
    11101 tgtttagtta cgatcagtgc catcatcaag atgtacgcaa tcttcatcaa ctctgctggc
    11161 tggaaagtaa acgcaccgaa tcgaaaccag tttttagacc ctgttgaagc agctaaattc
    11221 tgatcataga atttgagcaa gagtcccatt accactaacc ccaaaccata aaggtaagga
    11281 gtcagtttcc agatccattt ggaattcaaa tgcatgatga caacgattgc tgccgctcca
    11341 actaaatacc agacaacttg catccctacg cctttcaaga ctgctggatt gttcggatca
    11401 tggctaagtg ctacatataa tgagagcaga ccaatcaaac ataacagaaa gactggtaaa
    11461 atcacgccat aatcaatacg attatcgttc gaagctttta attttttttc catgtttcat
    11521 cccttttctt aaaaaccata ctgctgatta ttatagcggt ccagttagat aatggaaagt
    11581 ctttccatag acatttggga aaaattaact ttccgtttgt gcagttgctt gagcaaatgc
    11641 agtacaaaag cctactgctt atctttagtg tatcatagaa ctttttttga tacatgcaat
    11701 tatctaccag ctgagattct cctcgctgtg agaagtttct gtgctttcat tgtatcgaag
    11761 gatctcttcg gcaatctcta gcagctgatc agaaaccaga ttggttcgtt ggatgaaata
    11821 aaaatatcga tggaaattca acggagtcat tggcacattt tctggaacag agcgcttaga
    11881 caaaatcgag cgaccgattc cttccttcag caacgcaaca attacatcgt tacttttcac
    11941 gatcatcttc ttatcttgga tattcatctc ttcaaaataa cgctgcgtgt aatgaaaaac
    12001 accagagttt gcttctctta caagccacaa tttgcttttt gggtccccag cgatgactag
    12061 ctggtcttcc atcaaagagt atctttgtac gccggaagtc tctaatggct tttcgataaa
    12121 accaaaatcg gattcatgtt tcgctacttg ttctaatgat tcatgagaat tcgtgatttc
    12181 gatctcaaaa tgcactttag gaaacctttt gatcagatgt ttcatcaact gaggcaaaag
    12241 atagacagca aaggtgtggg aagcaacgat ccgacatact tcttcttcat tttgttcatt
    12301 gagcaatttt tgctgagttt cttcccattc ttctaacaaa accagtgtcc gttcatataa
    12361 taagtcggct tgcttagttg gaagcatctc ttttcttccg ttacgttgaa aaagatcgat
    12421 attcaattcc cgctccaact gtttgatttg attcgagact gctggttgag ataaaaacag
    12481 tacttctgct gctctggaaa aatttcttgt ttcatatact gctcgaaaag tcgttaataa
    12541 cttaaacatg gcaccacttc cataactttt tatgataatt actataaaaa ctatttgatt
    12601 taaatataca aaaaaccatc tataatagaa atgtacaaca aaacagttgc tgatccaact
    12661 agtaacttag atgaagacaa tcagctgtct gcttgctcgt aatcatacat tcctattcat
    12721 tttacaatgt attcgttcat cttggtacta aaatctatta aataaaaagg agaatattat
    12781 atatgaagaa ctttttgaaa attattccga tcccgatctg cgggttgatc cttgggttag
    12841 cttcccttgg aaatctgttt aaagactatc accatgttgc tttaggcaat ctaactggcg
    12901 gtatctctat gattcttatg atattcattt ttgttaaatt gtttatctta ttcgaacaca
    12961 cgaaacaaac gttgcatgat ccaatcatcg cctccgtttc accaactttt acgatgtcac
    13021 tcatggttat ttgtacttat tttgtttcat atgaaagtat tgcaccaatt gtcaaattca
    13081 tttggctgtg cgctgttatc ttccaagtga tccttgtctt ttatttcaat tatcaccatg
    13141 ttatcaaagc tgatctttca attgaagcaa tttatccaag ctggtttatc atttacgttg
    13201 gatttggggt catcactgta actgccggga acttcttccc acttattgga aaaattttct
    13261 tttggatttc attgatctgc tatgcgttct tattgccgat catcatcaaa cgtgtctttt
    13321 tcgtaagaaa tatggctcat ccgacacgtc cgctgattac gatcgttgca gcacctggtt
    13381 ctctttgcct aacaggttat cttaaaaact ttgctgaacc taatttttat cttgtcgtag
    13441 cattgttcgc tttatctcaa gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt
    13501 tcaagcttcg tttttatcca agctatgcag cctttacatt cccgcttgtt atctctgcaa
    13561 cagctatatt tactactgtt cattacttca acagtttagg tatctatagt agcgtattgg
    13621 atttcttaaa agttgcggaa tgtctgtttg caagtgtagt tgtcttctac gttcttgctc
    13681 attacgtacg tttcttaatt aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa
    13741 tcgcttaata atcgattcaa taggttgtga aaaagctgtt ctgcatcaag taataagaac
    13801 ggccaaacaa aaacagctgt tcatgttttt gtactggttg ggcttattac cgcagatgca
    13861 agcttttgaa caccgtttac caagaggtcg taaaagaagt ggtcagcttc aagaaataag
    13921 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa
    13981 gctacttctg gaacaccgtt tattcgaaac aagaggtcgt acaagacttt tgtcacgacc
    14041 tcttgttctt ttgtcaaaat actggtttag tgctactatg ttcgagtatg cttttagtat
    14101 ttattgacga aaggaaccga tcaaatgaaa tcattgtcac atccaataaa atctgtaaag
    14161 gattcagcgg tccgcgaaat cttacccggt ttactgcttt cttttgccat cgctgccttc
    14221 agcaggcttc ttgctattta tctgccacag ttaggtggag cgactattgc tattttattg
    14281 ggtattttat taggaaatac tttttttaaa cagcctgttc tagcaatcgg cacaaaattt
    14341 gctgaaagca aactattaga attctctgtt tttttactag gtgcaactgt cacagctcaa
    14401 acgattgctc aaattggtgt aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact
    14461 atcatcggtg cttacttgat tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg
    14521 atggctggag gaaacgctgt ttgtggttct tctgctattg cttcaatcgc cccttccatc
    14581 catgcgaaag aggaagaaaa aggacagatc atcacactag tcaatctact gggtactgtg
    14641 atgatgttga ctctcccttt tcttggatta cagttgtttg gtggaaatct cattgaaaaa
    14701 agtgcacttt tgggtggtac actccaatct gttggtcaag tagtcgctgg ggcaagctta
    14761 cttgacaatt ctgttgtcga attcgccatg ctatttaaga ttctacgtat tatgatgctc
    14821 gttgttgttg tctatctgtt tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa
    14881 acgccaactg atacgcagaa aaaacgaaaa ttaccgcttc cttggtatgt attagggttt
    14941 gtgatctttt gtttggtcaa cagcttgttt tctttacctg tagttattga ccaatcggca
    15001 cattttatca gcagctggtt tgagatcact gctttagcgg caattggtct gcgtttagac
    15061 tttgcaaaat tcatgaaaga aggtacacgc ttcttatctt atggattagc tgtcgggctt
    15121 ctccaaacag tgatggcttt actatttatt tggctgatca aagtttagaa tgaacatgaa
    15181 aaaacagttg tgattctcgc atggaacaat gtccgaatca caactgtttt taattttgca
    15241 gatatccttc taacaacaac aattggcgtt tgatttcaac cccatctatt gcgtttccca
    15301 tatatcctgt cagttttcca ttttgcccga tcactcgatg acaaggaata acgattggca
    15361 atggattggt tcgatttgcc tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa
    15421 cggctacttc tttatacgtt cggatttctc cataaggaat ggtcgacaaa gctttccaga
    15481 cattttgctg aaaaggcgta cctctcttta tagataaagg aacatcaaat tcttttcttt
    15541 ttcccgcaaa atattcttca aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg
    15601 attcgctttc tgaaattggc tgaaaagata cagcagtcaa tccggattca tctgcatcta
    15661 accataaaaa gccgataggt gtgtgtattt tcattttgtt tgctcctagt caatagactg
    15721 gaacttcctc ctttttctct atccaaaact acttgccaac taataaaaat tgttcttaaa
    15781 agtttgataa accgaggaaa catggtaaac taaatacgtt agtttacaaa aagaatacct
    15841 gttcttttac gtaaaatcaa attttaaagg tgttatttaa ggtttattaa attttgaatg
    15901 taaaccatat ataaacatac gattgaaagg atagaaacga tgaaagtatc aattgttgtc
    15961 ccatgtttta atgaagaaaa aactgttcct cttttttttg atgaggttga aaaattcaaa
    16021 ggtgcccatg agttcgaata tttgtttatt gacgacggat caaaagacgg tacgttagca
    16081 gcaatcaaga agctagcctc agcttatcct tatgtccgct ttgtctcatt ttccagaaat
    16141 tttgggaaag aagcggctct gtacgctgga ttgcaagctt ctacaggaga tttagtgacc
    16201 gtgatggatg ttgatctgca agatccgccc gaactgcttc ctgagatgat caaccggatc
    16261 actacttctg atatcgattg tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg
    16321 atacgcagtt tctttgcgaa aaaattctac cagttgatca ataaaatcag cgatacagaa
    16381 atggtcgatg gcgctcgtga tttccgcttg atgactcgtc aaatggtgga tgccgtccta
    16441 gaattaacag aatacaaccg attttcaaaa ggattattta gctgggtcgg atttaaaaca
    16501 gaatatattt cttatgaaaa ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg
    16561 aaattattca actactcgat tgatggtatc gtgaacttct cggatgcacc gttaacgatt
    16621 gcttcattta tcggcgcttt gtcttgtgtc ggttctggta ttgcaatttt gttcattatt
    16681 ttgcgggcat tgttgtttgg tgatcctaca tcaggatggc cttccatggt ctcgatcttc
    16741 ctgttcattg gtggaatcca attgttatgt cttggaatca tcgggaaata tattgggaaa
    16801 atcttcttag aaacgaaaca gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag
    16861 ccaaatgaat tgaagcctca ccaataatat acgtcaaatg aagtaaacat ttttttaaat
    16921 gaaaaaggac tgtgacaaaa gtcttgtcac agtccttttt tccgaataaa tggtgttcca
    16981 gaagtagctt cttcggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
    17041 aattccttct tatttcttga agctgaccac ttctatcaca acctctttca tatcttatta
    17101 cttcttcatt gctgctttta gtgctgctgc taatgggctt tcttctggtt cttctgcttg
    17161 tgcatatttt ttcagcaagc gtcgttcttc atgtttggtc attttcttct tctgctcttt
    17221 tttatcaagc aatttttctg tcgttccatc gtatttacaa cggaaataag caccgttttt
    17281 accttcgatg atttccattt tccggtgaca ttgcgggcat cgatgattag agacttttgg
    17341 atcttttctt ctgcggtagt tgcaatctga attggtgcag acatagattt tgccgtcacg
    17401 tgtgtttttc tcgcgcagat tggccccaca ttctgggcat ttcttttggg taatcgagaa
    17461 atcttgatat tcttgtttgc ttgatttgat ctcattcacc aagcgttttg tttctttttc
    17521 gattccattc aagaaggttc ctgcttgttt ctttcctgca gcaatagctt caaggtcttt
    17581 ttcccagctt tctgtcaaat ctggtgttac taaagaggga tttaccaata ctaataattg
    17641 cttaccttta ggagatactt gcagtccttg aggggtacgt tccatcagtt cagatttgat
    17701 tagtttctcg ataatctctg cacgcgtagc tggggttccc agactgtatt tttccatttg
    17761 accaagcaag cttgcttctg acaatggttt aggcggtgca gatagttctt ttttgatggc
    17821 gaaatcggga ttgattctca ttcctttttc ccatttgact gtttccgtct cagtttcagt
    17881 ttcgcctttc catcctgctt ggacgacacg attttgccga aaaatgaatc gttctttacc
    17941 aaattcaacc gtaacttttg tttggctgac tttatggggt tgagcaaaca gtcctaaaaa
    18001 acgagagaca atcatttgat agatttttcg ctcttcatta cttaattttt cataacgtgc
    18061 tctgttttca gttggcaaaa gtgcatggtg atcggtcact ttactgtctt ggaatacttt
    18121 tgtctgttgg acgatggctc cgtttttcaa atactgcttg acctcaggag caaagtcgct
    18181 gactgcttgc aatcgttctt tcatcgtact tttcatgtca tttgtcagat atttgctgtc
    18241 tgtacgcgga taagtaacga tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt
    18301 tttctttgca gaatagccat agcgttgatt ggcttctctt tggatctctg ttaaatcata
    18361 aggcaatggc gcagattccg tttttaattt ttcttggact tctgtgacag ttcctttgct
    18421 tgtactgatc aattgaacaa gtttttgtgc ttcttcttgt gtttttaaag caaattgatt
    18481 tttttgaagc attttggctt gttcttttcc agcttgcaac gtgatcgtga aatacgtttg
    18541 tggacggaac tgctcgattt tcttttcttg gtctctcact aatgctagtg tcggtgtctg
    18601 cacacggcct gctgataaat tatccgcgta cttcacagtt aaggctctgg tcacattcaa
    18661 tcctaccagc cagtccgctt ttgcccgggc aagagcagat tcatacaatg catcatattc
    18721 tttcgcaggt cttagttgct tgaatccagt tttgattgct ttatctgttt gagaagagat
    18781 ccataaccgc ttcactggtt tattgaaatg cacatactct aagatccagc gagcaacaag
    18841 ttccccttct cttccggcat ctgtcgcaat gactgcttct gagacatctt ttcgctgagc
    18901 cagctgcttg attgctttta attgatgtcc tgttttagga agtggtttga ttcctagttt
    18961 tttagggatc attggcaacg tgtccatttg ccagctctgc cattccttat tcagatcttc
    19021 cggcattttc aatcctaata aatgaccaag ggcccaagta acgatcacct tgggtccttc
    19081 ataataattt ttgtgctttt gattagcacc aagcaccttg cttaggtctt tcgcaacgct
    19141 tggtttttcc gctagaatta gttgtttcat aaaattcctt tctgctttct actgtgatgg
    19201 gctgatgatt tttcaacaac gcaagtccct tgtattgctg taaatcatcg tcacactctt
    19261 cacaccagcg ctcatctccg tcattccaaa aggcgctgag aaagttactt tttgcattga
    19321 tatattcata attttgatgg atttcgttcc attgtttttc gtacgcttgt cgtgcttctt
    19381 cgaaagactc gaatgtttct tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc
    19441 aaggctcatt gtccccgaac atggtaatta cttgatacat actcgtgctc cttctttcag
    19501 cttttctaga ctcatcttag tcacttttca agaaagttgc aagaattttc tcttataaaa
    19561 gggtcattta atgaacatct taaaattgtt acaaatgaat ctgattgttt aaggcaaagt
    19621 agcgataaag ttattgatca tccaaaaata gctgtcttct ggatcgattg ttggttcttt
    19681 tgtaaagtat cctaaaaaac gtaaggaaag ataaccgtgg atcatactac gaagttccct
    19741 gcttcgatga actttttctt ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat
    19801 ctgattcgtt tcatggattc catctaataa aacagcttca ttggtatgcg gtacactgat
    19861 cagtaactca tacactgctt gatttgaaaa agcaaaggat cgataagttt ctgcatagat
    19921 ctgcagtgct tcctgaccac tttttcccac aagagcccgt cgcagctggt cattaagttc
    19981 ctgcagaagt ttcgctgtta gcgctgtttt gacatcacga atatttttga aatggttata
    20041 cagcgaggga gccttgatat ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac
    20101 atccatctct tctgctagtt ctcgaaagca gtcgatgatt ttctcttgag acagatttct
    20161 ttttttcatt tccatgtttc ctctcataaa ataaatcctt cactctttca gtttaccacg
    20221 aaaaagaaag agaaaaaaga gactttcatt gataaactac atattgtagt ttataataaa
    20281 gagctgtaga tgaaaatttt cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa
    20341 aattatttag gaaaagagaa acttgggaac aaaacttgtt tgtcttatgg tttggaacat
    20401 ttatggctgg tatcggattt agtttagtca tgccttttat gtcactttac atagatacgt
    20461 taggtaatta tagtacgtca caattgaact tttggagcgg attgactttt tcatctactt
    20521 tcttggtgac tacgcttatc tctccttggt ggggaaaatt agccgaccaa aaaggaagaa
    20581 aattgatgct gttgcgtgct tcattaggaa tggcaatcgt catttctttg atgggttgcg
    20641 tgactagtgt gtatcaatta gtcgcattgc gtctgcttca agggattttt tctggttata
    20701 tcagtaatgc cactgccctt gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc
    20761 ttggaacctt agcaactggt tctgttacag gaacattact tggaccgctt cttggcggga
    20821 tctctgcttc agcgtttggc tatcgcccta cctttttcat tacagggatc atcttatttt
    20881 tcgtcttctt gttgagtctg tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa
    20941 acatggtttc tgccaaacag attttcaaag acttgaaata tccacacgtc gtcatcggta
    21001 tgttcgtcac aacgatgatc atccaagcat ccaacaattc cattagtcca atcatcagtc
    21061 tgtacattcg ccaattgctg catggacatg ggaatgttac gttgatcagc ggaatcattg
    21121 cttcgatacc tgggattgcc actttgatag ccgctccaag atttggtcgc ttaggtgaca
    21181 agattgggag tgaaagaata cttgcgattg gtttgggttt tgcgattctg gtttatatcc
    21241 caatggcatt cgtcacgaat gtttggcaat tagctgcctt acgttttttg attggtatct
    21301 ctgatgcttg tctgctccct gctgtccaag cattgatcac aaaatattcg cctcatcaag
    21361 ctgctggacg gatcttcagt tataaccaat ctttccaagc aactggtaac gtagtagggc
    21421 ctatgatcgg ctccagtgtt tccagtgcat ttggttatcg cggcgtcttt ctttcgactt
    21481 ctcttcttgt tttggtcaac ttcttgcttg tacgacacaa tacacaagag atccatcagc
    21541 aagaaactgc agaagaaaaa gcttcaggag tctccatagc ttcagggcac tctccttctc
    21601 atagacaata agcgtaaatg aaaaacactg cttgaacagt tgtcacagac tgtccttgca
    21661 gtgtttttgt ttaggcctgt tttttcaaga actcagataa gaggaataat cccttttcca
    21721 aggtttcttt tttacaacag taacctagtc gggcatgctt cggtaaatca aaggcacttc
    21781 ctggtactaa tagtactcct gtttcttcta ataaattgat acaaaatgtc tggtcatctt
    21841 cttcgatggc taatttaatg aaagaagtag agacgtaatt gggagcgaca agttcaactt
    21901 tcggttcatt ggctacccat tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt
    21961 ttcgcgccaa tattttttct ttattcttca atgcatgtac agcaagatca tctgacagga
    22021 ctccgccgca aatcatcgtg tagtctcgat actttcgaaa aacttctgcc aactcaggtc
    22081 cagtagctgt ccagccaata cgaatacctg gaatggagta ggttttggat agggaattgg
    22141 ttgctatacc tttttcatag acatctacga tcgacaagaa ttcaccttta tccgttaaag
    22201 gcgcatatac ttcatctatc aatacatatg catctactgt acgagcaatt tctgcgattt
    22261 tttctaaagt tttccgatct agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga
    22321 tgatttttgt ttcaggtttg actaaggctt ctagctgttc taaatcaaac tgccaatctt
    22381 cttcttcctt caaatgaaca aagtcaacag cggcacctaa agatttgggg atgtcatata
    22441 attgctgata agtaggaagc atcgaaacaa catggtctcc tgcttccact aacgcgtata
    22501 gagctaaaag attagcacca gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg
    22561 tttgataaag agaagcgact tcttgtttga aaacatctga tccttcgatc cagccatagt
    22621 ccaatggttc gtttttgcgt ttttcgaaaa atttacttac gctagtccca tctaagccaa
    22681 cgagttcgtc taatgtcaat gcttcgatcg agctttgtgc aatatcatat accgctttct
    22741 tttcccattt atttagccat tcttctacac cgaaatttgc gattttcatg tttctttccc
    22801 ccttatatct tgatccagcc tacagcaagc aacccgattg aaagcagtgc ggccacacaa
    22861 atcagcccaa tcattacttt ttcttttccc gtaatttgat gtttggtttc acgacaagcg
    22921 atccagtaga agcaaaaacc aggaagatag gcaatactac ataaaaggac ataagaaaat
    22981 cctgctaaaa tgatgcccat caattcaaaa actacagcaa tcccaccgat cactacttgt
    23041 tttttgattc cttcttttaa agaaaactgg acttgataga tcccgacaag tagataacaa
    23101 atcaaaattg ccgctgtaca taaagaatag gcaaattgat aggcataatc agtaactaag
    23161 aaagtcaata agaatagatt agtcaagatt gcagtaacaa ctaacgaata agttggggca
    23221 ttttttttat tcgtttttcc ccaacctttc ggcaacagac cgtctcgagc catcaacatc
    23281 gttgtttctg ctgggagcat cgtccaagac aaccaagaac caatgatcga aataatcaag
    23341 ccgatattga tcagcgctgc tccccaattt cccacgattc cttttaaaat atttgccata
    23401 gcaggttgtg aaatagttgc taactcttct tgagataaga cgccgtatgg caagatcgaa
    23461 gcaaggatat agataaacaa taaacaaagc agaccaatga tcgatgcttg ctgggcttct
    23521 gaacgtttct tcgcgcggtt ggctaaaaca cttgcgcctt cgatccctac aaagacccac
    23581 atcataacca tcaaacaacc tttaatctgc aaccagatcg ttccttgctg ccctgttcca
    23641 ttcactagat tatcagatac gttaccccaa aaatcagcag tgaatatatt cactttaaat
    23701 gcgataaata caaatattaa aaataggaat aatggcacta atttacagat cgtcacgatt
    23761 gtattgatga cgctcgctcc ttcaactcca ttgtttacta ataaagtcag accccaaata
    23821 aaaatacttg caaataaaat agaaggaaca ttttgtccac ctttgaatat cgggaaaaat
    23881 tctcccatgg cgctcatcag catcgttgca aaagcaacat ttcccagcca cgcagacaac
    23941 cagtaacccc aaccactgat gaagccacct aatttaccaa atgaagcttc cgcgtaaccg
    24001 aaaataccac catctagatc tggacgcttt tctcctaaat gattcagcga taataccaaa
    24061 gctaaaatac caatcccaac gattatccat gaaaggatcg ctggccctgg agctgcagaa
    24121 ctagccagat cacttgtgat cccaaacaca ccgcttccga ttgacgaact gacaaccaga
    24181 gcaaccagtc cccatttgct aatacccgtc gatttctttt ccatttccat caccctcact
    24241 tataaaattg aacaaatcac ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt
    24301 aacaaaaagc aactttattc atattattgg atattatgaa ctttttacac aagtatttca
    24361 agtataaaat gaataaaaat taattttatt gcaaaaaaac agctatgcta tccaaaagaa
    24421 aaggtgtttc ttttgttagc catagctgtt ttgattcatt taatatcgct taaacgtatt
    24481 gtaaaacttt tgtttcttga tatgcgtggt cgatcaaacc accacccaga cattccattc
    24541 catcataaaa tacaactgct tgtccaggag tgattgcacg tacaggttcg tcgaatacga
    24601 cttctgcacg attatcatcc aataagcgaa ctgtcacagg aacgtcttgc tgacgataac
    24661 ggaatttcgc tgtacacttg aattcttttg gcattggttc attcgtcgta aagtggattt
    24721 cacttgcatc caagcttgtg gcatacaatg caggatgatg gaacccttgc cccacatata
    24781 atgtgtttgt cgctagatct tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc
    24841 caccgatccc tagtccttga cgttgaccaa tcgtataata catcaagcca gcatgttgtc
    24901 ctttgacttc accatcaaga gtgaccatat ttcctttttt tgctggcaga tagttgctca
    24961 aaaattgttt gaagttcttt tcaccaataa agcagattcc cgttgaatct tttttcttag
    25021 cagtcgcaag gcctgcgcgt tcagcaattg cccgtacttc tgatttttcc atgccgccta
    25081 gagggaacat cgtttttgaa agctgttctt gtgataattg gctaaggaag taagtttgat
    25141 ctttattatt gtctactcca cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt
    25201 gcgcataatg tccagtagct acataatcgg cgccaagatc cattgcataa tccaagaatg
    25261 ctttgaattt gatttctttg ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt
    25321 attcggctag gaaatattca aatacacgat cccaatattc tttttcaaaa ttcacagagt
    25381 aataaggaat cccgatttga gcagctactt tcgctacatc cttataatct tccgtggccg
    25441 tgcatacacc gttttcgtcc gtgtcatccc aatttttcat gaatattccg atcacgtcgt
    25501 atccttgttc ctttaacaaa agtgctgtta cagatgagtc gacaccgccg ctcatcccta
    25561 cgacaacgcg tgttttgctg ttgtctgtca tgatatcacc atcatttcaa ttagattctg
    25621 aaacatctac gagttgaagg tcgcaacttt tcagtatttt acattatacg tcatatttct
    25681 gaaaatttca tcccttaatt atcaagtcgt aaaaatactg ttctactgga cctattcagt
    25741 acacaaacat gatagtcaac caaaaaatca ctcatctttt gagcattcga tataaaaaat
    25801 tggcatactc ataaaaaggg ccagcctttc ggcaataagg aataatttta taaattgtga
    25861 aaaactattt ttcaaaattg cttcttatcg cttaaagctg cacgtctcat ttacaacctt
    25921 ttctttttag atgttatgag ttgctcagat aagtgatttt gtttactcta agaaaaaagg
    25981 gaggcaaaag atacatgaat tactttatca gtgatatgca ctttttccat gaacgcttat
    26041 taggaaaaaa cgactttgct ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt
    26101 tgatcactag ctggaatgca gtaataaaag aaaccgacca tgtttatcat ctaggcgacc
    26161 ttgctatgca tccgcaatat gaaaaagcaa atgcagaaat tttggaactg gtcactcaac
    26221 tgcaaggaac aatccacttg atcaaaggga accatgacag tcgcgctttt ttccgttatt
    26281 tagaaaaaaa tgatcctagg cttactgacg gaagtcccaa attttatttt tatgatgtag
    26341 gtgccatcgt taaattcgac catcaacaat attacttgac tcattatccg atgttgctcg
    26401 ggcctaacga cactatccgc aatcttcatg gacatatcca tcattacagc gtacctatcg
    26461 agaacgatgt caatgtaggc gtagacgcac cggaaagaga actcttaaag gaaaaactac
    26521 catttggcac tccgttatct gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt
    26581 acgataggtc gtgaaaaaac tgccctatat caagtattaa acaaataaag ataattactc
    26641 atatttttca tttgagtagg cttattgcca caggaacatt aggatcagaa atggagttgt
    26701 aacaagactt ctgtcacaac tccattccat actattcgtc tttttgctca tggtgttctt
    26761 ttaccagttt tttctgtaat tctttatcat aatttcgggc agctgacgtt aaaaataaaa
    26821 cgattccgca taataaaatc ccgattccgg aaaacaagaa cattttttct acccctaaac
    26881 gatcagctaa tggtcctgca aataataatc caattggacc tgccaggttc atcaaagagt
    26941 tgaagttccc taagacacga cctaaaacat tcgattcata actctgctgg atcattgcca
    27001 tcagcagtgt attgaaatat ggcgttgcac aacctgctcc tgcattcaag ataagaaagt
    27061 acaagaaccc ttgactatcg tttggaacca atccgcttgc accgatcgtc aggcccataa
    27121 tgatgtaggc tataataata ggtttcattc ggtctttcca tgttcctata aaactgatca
    27181 gtgcaccgcc taagagcatt ccgactgcgt agactacttc cactgctccc gcctgtccaa
    27241 cggaaccacc aaagtaatct agcgtcatca atggatacag actgattgct ggcatgaaca
    27301 acagcatcac aaatgcacca ttgatcgtta tgtaccataa ccctttatta tccatcaatt
    27361 gctgcagccc aaattttgca tctttaaaaa tagtaagcgg aacttccaat atttcaggag
    27421 aaacttttgg gatcttcaca aaaatcaata agccgacacc aaaaactgcc cccaatacat
    27481 ctaataaaat aaggtaattg acaggaacga ctgaaaacaa agccgcacct agagctggcg
    27541 caatgatgaa attcgctgat tggaccattc ctaactgtcc attcgtcctt gttatgtgag
    27601 aagatggaac gattgtcggc ataatcgact ggatcgttgg catttggaat gtttgtgcga
    27661 ccgaacgcat aaacaaagac acaaaaacta gccaaatcgg gaaggattct gaaatcgttc
    27721 cgactactgc taaaataagc gcgaaaatcg ctacaataat atccgtgaca atcaaaagag
    27781 cttttttatc ccagcgatcc actagcggtc ctacaaatgg gcttagtaaa accatgggaa
    27841 tcattcctag taaagtagca aaactcaaaa ttgtcgccga accggtttct cttgtcaaat
    27901 accagatgat cgcatattgg acgaccatac tagtgattcc tgacaaaaac tgtcccgata
    27961 aaaagaacaa ataatttctc ttccaattcg ttaaaacgac cgactgttca ttttccataa
    28021 acatccctct tttctttttc attttgtata gcgtttgcac aacaatcatt atacgggatt
    28081 cttttttcaa aaaatacctt tttccctaaa taacaatcgt ttcaatttaa atttctttac
    28141 ttagaaacaa taaatcagca aaatattaaa aataacaaca tgtgttaaat ttaaaaataa
    28201 aaaagacaac taatttgcgt cgtccttaca aagttagtca tctaacaata ggccgtttca
    28261 aaactagttg tctttttata tccacagatc attcgacttt ttcgaataac ccacggctaa
    28321 tcatcccatc catcagaaaa taaaatttat cttggctcat tttctgtttt ggatctttga
    28381 aaatattgac tgctttcaat ccatttgctg tagtgatcga cattttcaat gtttgaatat
    28441 cttttgatac agtgattttt aatttgaatc cttctttgct ttgcggcgtg gcatctaatg
    28501 gtcggatcaa ttgataattg cctccgtttg tttctgtaaa tccattatcg cgcaatgtat
    28561 atctttttgc atcaggatgc aaacgatagc taattggtgc gcccagtacc gttgctgttg
    28621 tttcaaatgc catgattttc acctcgataa aattagtttc tctttattat aaaagtttat
    28681 cctgattttt actaggtttt tcagttaagt tccctaaaaa atgaaggcgt tctctcagac
    28741 atctgttcat ataagaatga cttcactagt tattttttga cagcacgaac taattgatca
    28801 aggaaatact ggatgtcgtc ttcggtattt cccaaaccaa agctgatacg gatggattct
    28861 tttagtatcg gtgtatcttc tccatacatt gcttctaata cgtgtgaagg ctcgatattt
    28921 cctgctgtac aagctgaacc agtagaaata gcgaccccat taagatcaag cttcatcagt
    28981 agcaaatcat ttgcttcgcc aattaagcga agattcaaca catgagggag tttattcgtt
    29041 aaatcaccat ttacttgata agggatttcg tttgcttcta atgtatcaag aatcaattgc
    29101 tggaatcctt tatatttgtt gttacgtgct tcacgttctt caggtgacag cagttcaact
    29161 gcttttgcca taccccagat ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc
    29221 tgctccccgc ctaaaagcaa tgcagggata tttactccgt ctcgtttata taagaaaccg
    29281 acgccttttg gcccattgat tttatgagca gagatactta ataaatcgat tcctaattct
    29341 tctggatgga tcgtttggtt tccgtacgct tgtaccgcat ctgtatggaa ataagctgga
    29401 tgatccgcta aaagttcacc gatttctttg attggcatca aatttccgat ttcattgttc
    29461 ccgtacatca cagagaccaa gatcgtatct tctcgtaacg cttttttgac ctcttcgatc
    29521 gacagattcc ctttttcatc tacaggcaga tatgtaacgt caaacccctt tgtctctaaa
    29581 tatttcatgg tattaagaac agcaggatgt tcgatagctg tagtgattag atgtctgcct
    29641 tctttttgac gcgagaacgc tgtttctaag atagctgtat tatccccttc tgttccccca
    29701 ctgttaaaga tgatctcgtg aggttttgct tgcagactgt ctgcaatgat ttgtcttgct
    29761 gtttccaatt tttcatgcgc gtggcgacca aatccatgta tgcttgaagg atttccaaac
    29821 gtgtcttgca tgattgccgt catcgcttca attacttgtg gatgcatggg ggtagttgcc
    29881 gcatgatcca gataaatagt tttcacttca ttcatccctt ccaaattatt gctaggcaca
    29941 ttctagcata aaatagcgaa caaaccaaag aagagctcat ttttgtctag aggacgtttc
    30001 atgggcatag aaaaaaggag ctgtgacaaa agtcttgtcg cagctccttg aagctgctca
    30061 cttctgtcac aacttctttc cctctttttt ttgtttattc gaattctttt tcttccagac
    30121 ggaataacgg actcatcggt gtattttcat ggatgcgttt gaccgcttca cccattaatt
    30181 ctgaacatgt aacgattgtt aagttttctg gatgacgatt ttcttctgtg aaaacagaat
    30241 cagtgataca aatatctttg attggtgcat tgtctaaaat acttttcgca tgatcggaca
    30301 ataatccatg tgacgcacag gcatatactt cttttgcgcc gttttctttt aatacatttg
    30361 ctgctcgtgc aagcgttgct cctgtgttca agatatcatc taccatgata catgtctttc
    30421 cttgaacatc accgatcaca taaccaccct cagttgaagc atcatctgca tgatctacga
    30481 tggctaatgt gctgttcaaa tattctgaaa gactacgtgc acgctgaaca ccgctgtttt
    30541 ttggcgaaac aactacgatg tcatctcccg tcagacctaa ttgacggtaa taatgagcaa
    30601 acaacggcat cgtaaataaa ttatctacag gaatatcaaa gaatccttgt acttgaaccg
    30661 tgtgcagatc taaagtcagt actcgagttg cccctgcttc ttcgatcaag ttagcgatca
    30721 atttcgcagt gatcggttca tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt
    30781 aaggcaatac gacattgatc gttttcgcac ttgctcgctt cattgcatcg atcatgatca
    30841 gtagttccat atagtaatca ttgacaggtg cattcgttga ttgaacgata tacacatgat
    30901 cccctcgaat actttcttcg atattgatgg aaatctcgcc atcactaaat tgcttcacga
    30961 cgcttttacc taattctgtt ccgaacactt tcgcgatttt ttcagctaat ggacggttgc
    31021 cattcaaact aaaaatcttc aacgtgtcat cctgatactt attactcatg tagtcctccc
    31081 caaaacttct ctattcttcg atagtttaac atatttttcc aagattttct gttaatttca
    31141 gcaaattctt aaggaagtga aactgttccg ttactccaac tggcaggaat gactttatga
    31201 taatcgcccc agttgtcgtg tactttgtaa taacgttctc ctgtttcagt ttcaaaataa
    31261 gcgtacgctg tcacccaatg attgccatat gtactgccaa gtactttcaa aataccaatc
    31321 atcacaggtt tgccttcacg tatacgtttt gtagctcgct gccatgaacc tagaagagtt
    31381 gctcgtgcac gctcatgatt gccattcttc tttaaaaaac tagaaatccc tgtactaacc
    31441 tgaaaaggaa tcgtaggaag tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa
    31501 accaacgaat cagccgtatt tttcttgcga atctcatttg gaagcatcca ccccttacga
    31561 tagtcttgat aataggcaag gagaactgct gccgcgtaag taccacaaag atagcctgag
    31621 ggggtagccc atttcttata cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt
    31681 gcgagttcct ttcctgacct tttttcttcg atcaaaacgg gaatatcttc ttttctgttg
    31741 atccatctag ataactcgat tggctcttca ttgatcagct tccatttttt acaagaaaga
    31801 ccctcttgat aagtatattt tgctggagaa tattctaccg gatgtcctga ttgatcgata
    31861 atcacataac tttgatcttc aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac
    31921 tgcagctgct gagtgctggc taatttttta atttttttat ctactttgaa atataaaggt
    31981 ttatccacta cttgattcag ttgggatcgc ctcctttttt tcattataag tgaaggattg
    32041 aaaaaaacaa atcagtttga ttgttcgaat tttcaatttt ttatgttcta tttgttaatt
    32101 ccttcatttt gtaagataat gggcacacga aacaaaaaag gagcgatcga tgaatgaaca
    32161 aagaacgatt gaaacaagat ttctatgaag cagtcaatga agaatggcaa aaaacagcaa
    32221 aaatccctgc agataaacca gctacaggcg gtttccaaga tttagttgac gggatcgacc
    32281 aacttttgat gggagaaaca gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa
    32341 aaatgaaaca tttccttgca tattatcaac tggcaaacga ttatgaccga agaaatgagt
    32401 tgcatgctca accgcttcaa cctataatcg aaaaagttga atcattgcag tctttcgacg
    32461 aattgaataa gcaatttcca gaatggctgt tggatacatt accattgcca tttaatctgg
    32521 atgtagatgc agatatgaag aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt
    32581 tattccttcc agataagacg tattatgcat cagaccatcc caacggtgca caactaatag
    32641 gcgttttctt tgatatggct gttcagttat tagagcttgc cggcaaagaa aaaagtcagg
    32701 cagaagcaat cacggaacaa gcagtgcaat ttgataaatt gattgctcct catgtaaaaa
    32761 gtgcagaaga aaacgcagat tacagcaaaa tgtataatcc gcaatctttt gatacattta
    32821 ttaaatacac agataaactg gacttgaaaa aacttgtcac gggtttgatt gggacaactc
    32881 cagataaagt gatcgtaact gatccagtgt acttcgatca tttgaatgac atcctgacag
    32941 aagctcattt tccgttattc aaaagctgga tgatcattaa aacagtacgt tctcttagtg
    33001 gttatctatc agaagaattc cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa
    33061 cagacgaagc aatgcctcag aaaaaagcag cgtattacct tgcctctgga caattcgatc
    33121 aagtagttgg cgattactac ggaaaaaaat attttggcga agctgctaaa aaagacgtag
    33181 aacaaatggt gaaaaaaatg atcgccgttt ataaaaaacg tctagaagaa aatgactggc
    33241 ttggggatgc aacaaaagaa aaagccgtca taaaattaaa taacttaggt atccaagtag
    33301 gctaccccga taagatccca gcattattcg accagttcaa aacagtacct gcagatcagg
    33361 gtggtacttt gctttcaaat actcttgttt tcagcaaact cacattaaaa gatcgtttca
    33421 gcaaatggaa caaaccagtg gatcgttcag aatgggaaat gagtgctgac acggtcaatg
    33481 cttattatca tccatttcgg aatgtgatcg tctttccggc agcgatcctt caagcaccat
    33541 tttacagtct agaacaatca agctctgcta attatggtgg aatcggagct gttatcgctc
    33601 atgagatttc ccatgcattt gataataacg gcgctttatt tgacgaatat ggcaacttga
    33661 acaactggtg gacagaagaa gatcttacac aatttcaaaa caaagcacaa gcaatgatcg
    33721 aagaattcga tggtctgcct tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg
    33781 aaaatattgc tgatgcaggc ggtctaagct gtgcattgga agcagcaaaa acggaatcag
    33841 atctttctat cgaggaattc tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa
    33901 aagaatacca acaactttta ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa
    33961 acgtgcaacc aaaaaacctt gacgaattct atgaaacatt tggtatcacg gaacaagacg
    34021 ctatgtatct agcgccagaa aaaagagtgc gaatctggta agaggttgtg ccagaagtgg
    34081 tcagcttcaa gaaataagaa ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt
    34141 cggcttattt ttcgaagaag ttacttctgg aataccatgt attagaggtt gtgaaaaagc
    34201 tgcttagttt caagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa
    34261 atttgactta ctaccgagaa actggctttt gaacaccgtt tatcgagagg ttgtgaaatc
    34321 agcgtcctga cctgagtatt agagaaaaaa acggaaaaat agttcctcat attttgccgt
    34381 ttgttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa
    34441 aagctgtcct gcatcaagta ataagaacag ccaatcaaaa gcagcaagga gaacctcatc
    34501 tataaaaaga tagaaggaag tgagacatct attggtctca tttccttcta tttttacttt
    34561 cctcagtcaa ttgttttaca tcataaaagg agaaattcca cttatttttt tcgctgtttc
    34621 atgacataaa caactacacc gattaacaaa attcctccag ctaatgctag caacgggtta
    34681 ttaaattctc ccgtttttgg gagtccttga gtgccatttt tttcactttc ttttgctgtc
    34741 ctatccggat gagaaggttt tccatttggt tttccatttg gtgattcatt tcctggattt
    34801 tctctttctg gtttgtcatt tcccgggggc acatcggcag tttctcgcac agtgatcgct
    34861 ttttgctggg taacagattc tgtatgagca gaccattttt ccccatcaaa tatttccgaa
    34921 cgataagtga cttctagcgt atattctcct tttgaaggtg ctgaaaaaat agcggtatga
    34981 ttagaaaatt gagcacttga ctgtgtttca acgatttgga tcttttctgg gaaataacgc
    35041 atatcttcaa agacaggcgt tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa
    35101 ggcttcagtt caatgatatt tccttctgca ttctccgcca caccatttgc ttcttgtata
    35161 ataatcggat tattttgttc atttggtttt gtctgatttg gttcttgtac gattgcatac
    35221 tctggatatt ccgaagacgg tgaggtttct ccgtcaaaaa tagcacctac agataatgga
    35281 agaccatcca ctctttcctt ttctgtttga cgattccccg gtttaatctg catcagtcca
    35341 tgaacatgga tacttccatt ttcatagcgc gtaacaggct gctgaccttc tttcgaacat
    35401 gtatttagag actcgatcca atcttttgat atggtatgtc caagagtatt ttctgattgt
    35461 ttctctcgtt cattccaata gtagttcaac gagtggtaga tttgatcttc gttttgattc
    35521 aatgggcgga tctgctctct catctcaaga ttctctgttc ggaaagataa gataccagaa
    35581 gcatggtagt ctgtgtttcc tgctgaagag gtataaagag ccacattata tgaaccgtta
    35641 ttaaaacttg tactgctatt gacgataata tctgttccgc tattggaatc gattcctttc
    35701 gcaagatttt cgaaagacaa actattgatc aattcatgag ggcccgttaa agaagaaccg
    35761 cccattttga atccattacc gttaccttct ccctcaattc ctggtaccca gccgtttcga
    35821 taagcaactg agtttttgat gattactttt ccgatcgaac ctgtttcatt tttagcaaaa
    35881 aggtcccaac cgtcatctgc attatgatac gcgatacaac cgtcaaatac atttccttct
    35941 cctattgtca gtttggccgc aaatccatcg gcatcttcaa atcctggatc ggcattttca
    36001 aaagatgtac agttcttgac taagttatgc gcgggccatg cttcgaaagg atcatttgag
    36061 ctaccgctga tttggattcc tgtatttcca ttccgataag catgaatctc ttcgatcaaa
    36121 ttatgatttc cagaaatctg taatcctttt tgcatagctg cactatttgt aatgtcaaac
    36181 cctcgtaaac cccagtagtg actgaacagt gtcatcccat ttccagttcc tttaaaatca
    36241 agtacaggac gcttgttttc tggatttttc tctgcaatca actgaatcgg gttttctctt
    36301 gtcccgttaa cgccttttgg aatcgtcaat cctctttcga aggaataagt tccaggcgcc
    36361 atgacgattg tctgcccagc atatgcgtat ctcaatgctt gtgtcagaga taatggattt
    36421 tgtctgcttc cgtttcctgc atctgaccct tctggtgtta cataaactgt cgaatattta
    36481 ggtttacggt agtccactgt atgaagaatc tcttttgttt cataactagt catctctacg
    36541 tattcttctg gcggatagtt tttatctggc gtaaaactga aagtaaattc gttcgttcct
    36601 tccatcagtt ttgtctgata atcaaattcc cgattcgcag tgatagccaa gttttttgcg
    36661 ttcttaagca cctctcctgt tgctttattt ttaattgtca ataatccgtc agcatttgct
    36721 ctaaaggaca tagtatgatc ttggtttcct gaatgattac tagaggtcac agtgtaaatc
    36781 ggatcaatca agcgagtagg tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa
    36841 gcaacttcga ttccttctac cttgatcgtc atattccttg ctgcagcaaa tcctgcataa
    36901 ataaccgatt catctgaagc gtataatttt tcccagtcat acatgatgtc agaagccatt
    36961 tcttctcctg tttcaggatc gtaataatat gcctctaaac cagtattcgt ttttttcatc
    37021 tctacgtcca gtttagtaat cgagttcgtg gccggaaaca gattcccatg accgtttccg
    37081 aatatattat aagaacctgt ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt
    37141 gtttccactg agacactccc aggagctggc gcagcttgcg gatcttcaga tgatattcct
    37201 gtgattgccc gtgtccccaa tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc
    37261 acttcttgtc tatccgagtc ccagacatat tcgatccgac tgcctagtat ggcaaatgaa
    37321 tttgaataaa atgcctgccc aaacaaatga ttttttggta ctgcgtctct taccattaaa
    37381 gcaaatcctt cttgggcatt cgtataggtc caagattcta tttcgatcgt cgcccgcatc
    37441 ctaaagttga tgtctttggg gattgcttga taataatagg tcattccatc tgatccgctt
    37501 gactggaatt ttccgccgtt attcgtggaa gagagccgca cgccgtcttc taatggttca
    37561 atggcatacc tactagcact tgtgctttct ccgaaaacaa cccctttcca ctcttcattt
    37621 gcttcttcag attgcttttt tgtcttttca ttttctgatt ctttcatcat aggatcattt
    37681 ccttcttccg tatccatatc ttcactagtt cttggtattt cctccattgt tgacatccct
    37741 tcaatgttca cgtgtgcatt ttcttcgttc acagactgtt gttcgttagc agcaacttca
    37801 acgacagaaa ttaaaaccgg ggtactgagc ataaggagat tcatcattag cgcactgtat
    37861 tttatacgtt tttttaacaa gtgtattcct cccgtaacaa attagaaagc gtttacttaa
    37921 agtattacct aatttatttt tactgtcaat aaaaaacaaa attataataa gtgtatttta
    37981 taaaaagaaa aaatataact taagttgttg ataataaaga gatttattaa cggaaaaaaa
    38041 ataagttttt ttaaaataac gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc
    38101 tcttctttta ttattttgtg ctttttattt tatcaaatca ctttgttttt ttataaaatt
    38161 tctgcgccta gtgtggactc aaaatgtctc aatgcccatt catgtccaac gggatcgaaa
    38221 cttgccacgg aatctttgaa aatatggagt ttgtatccta gattatacgc atcgactgct
    38281 gtatgcaaca cacagatatc tgtacatacg ccggtcaaat aaatatctgt gatctggcgt
    38341 tctcgcaaac ggatgtctag atctgttcca ctaaaagcgg aataatgccg tttgtctatc
    38401 caataaacat tttcctcttg ctcatagtct tggtataaac tttttaaaga gccgtacaat
    38461 tcccgtccac ccgttcctat cacattatgc ggaggaaata agcggttctc cggatgaaag
    38521 gaatcttttg gatcatgcgc atcaatggca aaaacgacaa aatccttttg atcaataaac
    38581 ttctttgtat gagcagtcag ctttttttca attacttgtc ctgctgtccc agtagtcagc
    38641 tttccatcct ctgcaacaaa atcatatgtg tagtcaatcg agatcaatgc gttcatctta
    38701 gtcctcctta tacgagatgt ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg
    38761 cgtcttcgat aaattcgtca aagctttgtg tcgccgagtg atctgctgtg tcgctcattg
    38821 cacgtacgat caaaaatggg atattgaact gacgagctgt ttgtccaaca gcggctcctt
    38881 ccatttcgca agctaatgct tcagggaaat tcgttaagat ttctttgatt ttatctggcg
    38941 agtcgacaaa tgtatcacct gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt
    39001 ttgctgcttt aaccatttca ctgcgcaaat atgtgcttgc ttcataatat agaggcattc
    39061 ctggtaattg tcctgggttg tagccaaatc ctgttgcatc tgcatcaaaa taagctactt
    39121 tgtctgatat aacgatgtca cctacttgta agccttcacc gattccgcca gctgaacctg
    39181 tattgatcac catgttcacg ccgtattgtt ggatcaacag acttgtggta atagatgcta
    39241 agacttttcc tataccggaa cgtacgacga tcacttcgtg gttacctaat gaacctgaaa
    39301 taaataaagc gcctgcgcgt tcccatgata atggttcgct taggttctct ctcaaaattt
    39361 ttacttcttc ttccattgcg ccgataatac cgattttcat ctttttaatt ccttctttct
    39421 atataaatgc gattgctaaa aaaaccacac ataacattag gataacaata ataagagatt
    39481 tcatcaaaaa agagttccat ttggtcgtct tttcccgttc gctgatcctt gttttcgtga
    39541 ttggtttatt ctttttgctt tctttacgat aaaagctggc aatctttttt tcttcttgct
    39601 gataagctgt ttctgctttt cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc
    39661 gcttgcgaag ttcgcttcgc gtaataagcg gtcctttggc cataagccga tccctctact
    39721 ttcctttggt caatagttcc cagtattgaa tcgcataaat cgtctttgca tcacaaatca
    39781 actgatcttt catcgcttgt tgcgcctctt caagagttag atgatacaac tccagtactt
    39841 cgtcttcatc ttgtgctaaa ggattctcga ccttctctac cccttgtgca tgataaatat
    39901 gaaggacttc atttgcaaaa cctggtgaaa gatacatcga agtaagatgg ctcagcgact
    39961 tcgcacgata gccagtttct tcttctaatt ctctagctgc tgtcatttcg ggattttgtc
    40021 cttctcctgg atcgattttt ccagctggaa tctccaaaat cactttttct aaaggttttc
    40081 gaaattgttt gacaagaagc agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc
    40141 caggatgaaa taccagttct ctcttcgaag ttcctccatc tggcaaacga acttcgtcta
    40201 cagcaacatc aataattttt ccgctataga tttctttgcg actgattgtt ttttcttcaa
    40261 attgctcatt gttcagcata tcttctcctg ctttctttgt aatcataact gctttttttt
    40321 catttttcaa tttttctcaa aaactcctta ttagtttacc atagataaac cttagatttt
    40381 ctctaaatat agaaaatcct tctttagtcc gatactcttt ctagtagtcc gtatgctaaa
    40441 ataagtatgt aatcgaataa cgaaaagaat tcaatactca acgataaatg acatggaggg
    40501 tttattatga taaaacgaaa ttggccgtgg cttctagcat tggtcttgct atttctcttt
    40561 gtccgaaaca atagtttttc ttttgttcta ggacttttat tgataggtgt agttttagtt
    40621 ttgtggggac tctttggttc gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg
    40681 actgacgaac ttgaaactca ctatgaaaaa agcggtatga cagcgaatga aatttcattt
    40741 tttcgacaaa caatgaatca aacaaaaaat gagatcaatc aattgcaaat gaatatgcag
    40801 cagacagcca aacttaaagc aatcgatctc cgccatgatc cagtcaaagc agcgaaagct
    40861 ttattcaaag aattggtgaa agaaccaaac cgactgcatg aagcaagtca gtttctttat
    40921 acgcatctgc cgaatctagt tgatttgaca aataagtata atgagatcaa tgaccatgag
    40981 atcaaaaaca aacagaccta tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg
    41041 tcagctttaa tcgcacaaga ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac
    41101 gtagagatat ctgttgcgaa acagagctta aagcgtgata ataaatatga accagaacaa
    41161 aaggattaac tcttttgttc ataaaagaag actcggaaca ttcagatgat gtctggctgt
    41221 ttcgagtact ttttctaaag tagagacatt catgtaagaa tcgagaacag attcaacaag
    41281 gaggaatttt ttatggatca taaaccgact gaaacaaaag atgttacacc agttaacgat
    41341 acacttgaag atttattgaa caacccgttt tcaactccaa cagatacgct gaccacttca
    41401 caacaagcgg agattgatca gctccaagag caacagacag ctgctcgttt aattgacaaa
    41461 ctaccggcgg aacgccaaga acaagctaaa cagctagcag caaaaatcga tgctaatgat
    41521 gcacagtctg tcatcagcta cggatcggct gcccaagcaa aattaagtga attctcacaa
    41581 tcgatgttga atcatgtgca agcacaagat attggtcctg taggagattc cttaactgaa
    41641 ctgatgtatc gtctccaaga agccaatcct gacgaactgc gtgccggaga agggaacatc
    41701 ttccagcgtg tcttcgggaa ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa
    41761 aagattggtg cacaaattga caagatttca gtgaaattag ataaagaaaa agacggtctg
    41821 ctaaaagata atctgatgtt agaacagctt taccagaaaa acaaagacta ctttgatgca
    41881 ctgaatattt atatcgctgc tggagaattg aaaatggaag aacttcaaac aacgatcatt
    41941 ccagaagcga tgaaaagagc agaagaaact ggcgatcaga tggatgttca gattgccaat
    42001 gattacacgc aattcctaga tcgtctggat aaacgtacgc atgatcttcg cttagctaga
    42061 cagatcacga tccagcaagc accacaaatc cgtttgatcc aaaacacaaa tcaggccttg
    42121 gctgaaaaga tccaagcatc tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg
    42181 atcgcattga ccttgcttcg tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa
    42241 acaacaaacg acttattgaa gaaaaattca gaaatgctga aaatctcagc catcgaaaca
    42301 gcgaaagaaa atgaacgtgg aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat
    42361 ttgatcgaaa caatccaaga gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt
    42421 catgcagaag tagagcttgg acacatggaa gaagatctga aacaaaaact gttggattta
    42481 acccaataga tcacctttcg cttgttacta aaacaaacgc ccaacaacag tttattacaa
    42541 ctgttgatgg gcgtttttct tatctttctt ctaacttctc cattggagtc tatttctcat
    42601 tcatcttgct gtgtccatag ccatagccaa aataaatgat cagtccaata accattacga
    42661 taccgaacac gatccatgtc acagtttgca gacgaagcat caatacaata caagtcaaga
    42721 tggagacgat tggcaatagc ggaacgaatg gcactttgaa ttctccagct tttggtttgc
    42781 caaacatttt tctcaacttc agtaagccta gactaacaag catcaaatag gcgagcgcca
    42841 tgatattcgt tagttccgct aatacattca atgggaaaaa tccggcaaag aatacagctg
    42901 ccacaccagc ggcataagtc gcttttttcg gtgtacgatg cttttgatcg atttctgtca
    42961 taaacttagg aagtaagcca tccttgctga cagcaaacag taaacgagca agtgaataca
    43021 tcatcgagat cgttaccgtc agtagcgtta aaattgcccc tacagcgatc accgcgccca
    43081 ctgttccatg tcctacatac ctcattgcaa aagccactgg gtcattgact cctagttcag
    43141 tatacggaac gattcctgtc aagatcagcg tcacgatgat gtaaaggaca gtagcaatca
    43201 gtatcgaacc aatgattcct cttggcacat ctttttgcgg gtttttgact tcctcggctg
    43261 ccattgcaac ggcatcaaat cccaagaaag caaaaaacac aagagctgca ccatctagca
    43321 caccggaaaa accaaaaggc atgaatggct gccagttatc aggtttaacg aaaaatattc
    43381 ctacaatgat aaacaacgcg atgataccaa atttgacata taccatggca ttattcaaac
    43441 gtaatgcttt cttggcttca agcgacacga tgtaagtgac gaatatcact acgagcaccg
    43501 caatcaagtc aatgtatgta ccattttccg gattgtaccc gccagttaat gcttgtggaa
    43561 gttcggcccc taaacttttc aaaaaacctt gcatatagcc agaccatccg gaagcaacag
    43621 aggaaaccgc tagtaaaaat tccccgatca acaaccaccc tgtcagccag gcagcaaatt
    43681 caccaaatac aacatacaga taggcatatg gcccaccaat cactggcact cgcgaagcaa
    43741 attctgcgaa acttagtcca gacaaaatga caacgattgc agctaagaca aatgaaagtg
    43801 acagtgctgg accagcattt tgattggccg caacccctgt caccacaaat attcccgtac
    43861 cgatgatcgc accaattcca agcatgatca aatcagacgt ttttagttct tttttcatct
    43921 cactcgtatg attgagattg atctctttct tacgaaacaa atccattgaa gttcctcccc
    43981 attttaggtt ggaaaacagc gattaaactg ttttcatata ccctaaaagg ataccaccta
    44041 aaatgactaa aaggcaacca acaataacat aaatgagctc ttttttcgtt tttctttcgc
    44101 caaggatgaa aatcccacct aaagtagaga taatgatccc catttgtgaa agtgagaagc
    44161 caacagctaa accaagtgat ttgactgtta gaagcatgca gatgtttcct aagccccata
    44221 ataatccaca gatcatgttt ttccacacaa actgatcgac tttaacttta cggaaagcaa
    44281 agaagcttgc gcctaagatc attccgatac tttgaggtaa gataattgac atcgcatcca
    44341 aattcgccca gttgacgatg atggtatata caccataacc aatcgtagag aagatcaatg
    44401 ctctaaaacc cttaccaaaa tcaagcattt tattatctgt atctattttt ccttcgtcat
    44461 cttgtcgggc agtcaaatac gcaccgctta caagaagagc taaagcaata ataccgtata
    44521 cataatcttt cgtttgtgtc cattcatgga agaaaacggc tcccgcaatc gtattcaaaa
    44581 ttaattgaaa accagtagac aatggtagcc ctacagaaac acccatgtac ttcattccat
    44641 ggaactgtcc attttgtcca acactccaag ctaagccgga taaaaatccg atcaagaaaa
    44701 tccaaggggt gattacagga ctaacaacga aaaagacaac taaagaaaac agaaatgcac
    44761 cgatcgtcat tcctagtgtt tgttgattgg catcgccacc aattttacca cttactaaac
    44821 caatactacc ccatgccaac atagggacta atgctattaa aatttccata accaatctcc
    44881 ttttatttca catgataaga aacttatcag cgaaaacgtt aacaacacaa gcactttttt
    44941 tcgtttctaa cgattttcta acgtttttca ttataaaaat ttaagattgg gaaaaataaa
    45001 gtcattgttg tcccttttcc ttcagttgat tcagccgtca aatggatacc taatttttcg
    45061 gccagatttt ttgctaaata aagtcctaat cctgttgaat gtgttttgct aagtcgacca
    45121 tttctcccag taaatccctt atcaaagatc cgtttcaagt cttccgctgg gataccgatc
    45181 cctgaatctt taactgaaag gctgactcct tgcgcttcct tttctatgct cacaatgatg
    45241 tttccgtgat ccggcgtata tttgatggca ttactaagca attggttgaa gataaaagcg
    45301 atccatttag catcggtcaa aacagtatga tcctcaccaa cgatctcgta gcgaatattt
    45361 ttttggataa aataatttgc ctgactgcgt atcacaggct gaatgattcc ttttagtcca
    45421 tattcttgga tgaggtagtc ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt
    45481 tctacgtatt catcgatttt tgataattca ttttctagta atgtatactt ttgatcgtca
    45541 atatcgaact cgatcgaacg aactagcaat ttagaagcgg aaagtggcac tttgatttca
    45601 tggacccatg agtcaatata atctttttgg tcttgttgat tactgattgc tgattgcatt
    45661 acttcttggt gttcacggat cagctgattg atatattctt ctaccagttt ttcttcttct
    45721 gtcctcccac cactcaaata attttgcaaa ggggaagttt tttgtatgtc ggctaatttt
    45781 ccccaccatc ttctcttgct caagtaacca cccagcagat aaaaaatcag aaagacgccc
    45841 tcaatcaaag ctaaataagc aattgtgctc aaatcaactt tgatgtttgg cgccagccac
    45901 atcacaaaga tcgtcaatgc aataaaaaac agccatccca agatcaatgt ccactgatct
    45961 ttcaaatatt taaaaaaatt catcttaacc gctcatcctt tcagggaacg atatatccct
    46021 gtcctacttt tgtttcgata tatccttgga tacctgcctg ttcgattttt cggcgtaacc
    46081 gattgatgtt gactgtcaat gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc
    46141 gcagcaattt ttcccgactt aagatctttc cattgtgctt catcaaaata aataatagac
    46201 gatattcatt tttgctcaaa tcaatgatct ctccgttgat ttccatactt ccgttgtcaa
    46261 cattcaacgt aatgccattg tggctcatca tttcactaga taattctgtg tagttgtaag
    46321 aacggcgaag taatgcattg atttttgcaa tcagtacatc gatttggaaa tgttttgtca
    46381 caaaatcatc tgcccccatg ttcatagcca tgatcatatc catattcgta ttcctgctgg
    46441 agataaaaat gatcggtact ttcgatactt cacgtatttt ttgacaccaa taatagccat
    46501 ccaaaacggg aagattaata tctagtaata caagctgtgg ttcttctctt tcaaagtctg
    46561 agaacacttg attgaaatcg gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct
    46621 ccatgatcaa ttgtcgaatg atctcttcgt cttcgactac catgattttt gccataaaaa
    46681 atccctccat ctttcttctt gctactacaa tatcaaagaa gcccttgtga aacaagttgg
    46741 cttacctgga aaatgtcatt ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat
    46801 cgcgtttgtc tcttccaagc agcttaaatt tattatgtta ttcttaataa ttggtctatt
    46861 atctgttatt tttctttcgt tgtttttgtc ttttaaattt tcgataacac caataaccga
    46921 aaagcgttag cactagcaat atacctagaa ggagtataag taatcgataa agatggtatt
    46981 tttttgtctg ttctatcttt gaagagactt cttctgtaaa gggaactcgt cttcctgtca
    47041 ctagtaatcg gtgagtgttc acggtgtaag gtgtacaagt gataagtgtg actagatcct
    47101 gcttttctct aattgctaat gtatttgttt ttgttggaag gacaacaatt ttctcaacga
    47161 cttcataagc gagcatccga ccatacactt caagatagaa tcggtcatct tgctccattt
    47221 cttcaagatc cgtaaagagt tttttctcag caataccgct atgggcggta atcacggaat
    47281 gtgtactctc tcctccagtt ggaaaagagg tgccttgcag gactgtcgct cctctatcta
    47341 acaaaagatc attcgtttca tcaaataaag gcaagctaac attgattttc ggaatataga
    47401 tggctccgat catatgttgt tcgtaatatt cttttcctgg attttggaca tttctaaccg
    47461 cttgctcaaa aggatctttg acttgtccca ttcctgggat tactgatgta tgagcaagcg
    47521 tctgattttt cttttcatgc actgctaatt gttgctcatg tttttcttct ttatcgcgtt
    47581 caagctgctt ttgataattc tcgatccttc tttgatccaa ataattgctg agagcatctg
    47641 ctaaaaatgg atatgtaaaa actgcagctc cggcaagaaa catcactgcc ataaataatt
    47701 gtaataaaag actgatttgg gtttgaggtc tattacctat tttctttttc attttcttca
    47761 ccttcttatt taaaaaaact gcagcaacct ttataaaacc gattgctgca gcttattttt
    47821 gttgcttata cttcagactt cattttagat ttacggtacc agctgtacgc tccaatcatc
    47881 aaacttattc cgattagtaa gaatgccaag agcccgttcc caccagtagc aggaagtgac
    47941 ccgcgtttca tattcggtac tctttctggc cctggatttt ctactcctac gatctgaatt
    48001 tcttcattat agcttccata agagatgata aattcagtaa aggctgcctc acctgttgga
    48061 agtacataac cttctggcgc catggtctct ttcatttgat aggttccata atctaaccct
    48121 tgaacctcaa agtatccatt tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc
    48181 cactcaattc tatctgctcc tgattcataa acagctaaag gcgactcccc tttataaaat
    48241 attgcgtatt cagaacggtc ttcattccac aattcgaatc ttgcatcttt aagcaattca
    48301 ctgcttgatg catcatattt ttcaaacttt cttccacctg ttgtgacttt ctctggcggc
    48361 tctactcctt cttcataatc aaattcatca tttcgtccga tttcaataac cgctgtgttg
    48421 ttatggaaat catccgcttc tagttctgtg gaaaccttca aattatacgt gatcgttaaa
    48481 tctcctccac gtgcatctgc taatctacct aaagtatcta ctttggctac tccattttct
    48541 tctgtcaaaa tcgtcacgac aaacccgttg cttactactt ctactatata atcttgtcct
    48601 tttgttaaaa tcgtctcgcc ggctcgcact tctatttcct gatcataata agttagacca
    48661 actgtaggcg tatctgtgat tttgtaattt ttgataacag cgcttccgtt ttcaaggaca
    48721 gaatcgatga aataaggaat aggtgctgtg atcgtgtaag aagccgtttt tcctctttct
    48781 agatcaatat aagaaatcgt ttcttgttct ccagcttcat taataatcgt tacttgtcta
    48841 aggtcgcttt cctctacatt catctgttta tctgcttctc tgatttcgtt tttcggatac
    48901 aaatgcacat ctgtattgta tgtgtctttc catgtagaac catcccacac gccatccacc
    48961 atatcaggca tcatcactgg catcataaca accattggag acgcgattct ggaaatatga
    49021 gctggcgaat aagtttctaa gaaaagatag actttatctc tagaagaagg tgcttcttcc
    49081 gtcacttgga cggtagagaa taccgcttct ccagcttcat tcgttgtttg tttgtcaata
    49141 cttgtcagtc gatattttaa aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc
    49201 gcttcggcag aattaagacc gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa
    49261 tcgtaatata cttccgttac gtcaaacaaa tcaaaatcga ctcctggaat attttcttca
    49321 ccaaaatccg tagaaaccaa tccgctattc ggtcgttctt ccggaacaga tgagaaacct
    49381 tttttgtgta atgtaatcgt cacttcactt ggtttttgtg cgacttcttc ggctttgact
    49441 agttttccgt tcccgaaaat ccctattccc gcagtaacga gtaacagtac actcattccc
    49501 gtgacaatca tttttttatt catttttttc tccccgttct ttttttatta ataaaacagc
    49561 acctaacaat aaaagaattc ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg
    49621 gaatacggac cattttcctg attgacctgg attgcttgga ccactcggct ctttcggttt
    49681 gtccgttgtt tcttttacgg tctcgttata aacacgtggt gttgcggatt cataggcaga
    49741 gactggaact ttcccggatt ctaattcagc catctcctgt ccgttaacta ctacatattg
    49801 tggttggcct tttgcatcca cccaaaattc agggatgatg acctcgattc tcttacttgc
    49861 ttcatccatc tcgtaacctt ccacaccttt taattcttca aaataatagg tgccagaagg
    49921 caagaaacgt tgtcctgtcg taacaaggcc ctctttatcc gaaatgaatt tgcttacatt
    49981 tttgtcattc aaaggatcat tgtctgctgg tttgatccat tgatttttca agtcattagc
    50041 aggagccata tctaaataat atttcccccc ttctatcatc tgatatagag caaaaacagc
    50101 accttctaat ggttttcctt tttcagttgt tcctctttga cgtccatact tgaagaagta
    50161 tggatctctt agataaccga catttttagg atagatatga atctcttgca gttcctcggt
    50221 tgattctgtc gggtgataaa ttggcaaaat agcagcaatt gggatagctg tctgatcgat
    50281 atcaacatcc aatccaactt ctggatcaat cgattcttcg aaaatcaaat aaactgcatc
    50341 ccgatcttgg tttttcttag gtgctttgat acgtgcaatc ccgtctccta atccgccaac
    50401 cgtatctttc ccagttgtta ccgaagtccc tatttggaca agcctttctt ctgtgattag
    50461 ctgacggata ttgtttctgt tcgtttcagc gatttgctgg acgaattctt taggagtcat
    50521 gttttcagca gctttttttt catgataata atcggtcatg tcgtaaatgg caaatgtcgc
    50581 tccatttagt ggcaccgtct gtgaaatgat atctgctgtt tcccctgctt cctcagagat
    50641 agccaagcca tcattttcat ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat
    50701 ccgtttatgc aacacgaatt ccacgacatc ttcccctgat tcttctgccg acatcgcatg
    50761 tggaagaagg actgctgcaa gcggtagtaa aacaagtaat tgaagcatca aacacaacag
    50821 ctttttcatt accttgctcc ctccttttta gattgtctga caaacaaacc ataggctgct
    50881 cctgcaagcg ccatgaagaa tgcagcaagc aggatataga ataatcgtcc ggatcctcct
    50941 gtagcaggca acggattttc aggatcgttc ccgacactaa gctgtaatct gattcgattt
    51001 gtctccaaaa gttcatattc taactcttgc tgtagatcag gcgtctctgc ttcttcgttt
    51061 ggataatacg aaatctcaac ttttagtgta cccgcttctt ttcctggaac tacccgatca
    51121 ttttctatgt caggttcttc tcgataacta atttctaaaa taaagtaacc tggaagtttt
    51181 ctatagctgt caggtgactt cacttccttg atccgataga ccccttccaa caagtctgaa
    51241 gcattgaata gggaagaatc gtttggatct ggtgccaagc ctccctcgat gatttcatac
    51301 tctcctgcac tattttgttt ctcaattgaa aattctgcgc cttcaagacg tcggctattc
    51361 atactgtcaa ttttcaaaag ttccaaatcg attggcgcta gttcatcttc taaggttact
    51421 tgtagtacac catcgatgat ttcatagcct tccggcaagg gagcagtttc gtcttcgatg
    51481 accgtatctt caatgataaa cttaccttct tcattcagtg caaactggaa cacttgatca
    51541 gatagccgat acccatttgg tgcgacagat tccgagacct catattcacc aatagacaga
    51601 tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta ctcctacggc acgagaatag
    51661 aagtatccga tcccaggcaa acgtttcgat tcttctggtt ctaacggatt accagtgtat
    51721 gctcgataca gcgggaagga agaatccccc actttcctga tatcgaaacc tgcaccatct
    51781 aatgtatggc cttcatggtc taattttcta actcggatct cccgataatc aaacgtattg
    51841 taagcagtga atgctaccca taaacgatcc tcttcatctg ttgtatacgt gagatattgc
    51901 caattttctt cacctgtttg cttgagttgg atagtcccta tagcattatc gtaaagtcgc
    51961 aagatccatg tgtcattttc atcaggttct ttgaaacctt ctgggttctg gctctcaatg
    52021 attttgtatt ctgcatagtt ggtagtttct tcactatcct tataaacaaa tgaatctggc
    52081 tctccgattg gatgaataac tttctcacca tccacgatta catatttccc gtcttcatct
    52141 actgaataga acgtgagtct ccctttctct tcctctactt cgttcacacc agaaagccct
    52201 ttcgctactg gatatccgat ttccagtccg ttaccatctg tttcataaag ttcaaactct
    52261 gcgccattga ttggcatatt actgccttca attagtttat tgatattcat gtggattggc
    52321 ttgaattcat ttcgcatttc cagtttgaca tacaactcat catactctgt gccttctatg
    52381 ttaggctctt gtacaacaga aagcttgtga tattctcctt cataatagga attcggatct
    52441 ttaccttccg gtccgccgac tctcgaacca gatgtatatt catctacaag ctcgtagtga
    52501 cctaacatct catcttcgtt ggctgcatat tttttgattt ggaattgata cgtctcatct
    52561 actaactgat aacgtggtgg tccagcgatc tctctgatcc aaaatatgtc gctgactgct
    52621 ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga tcgctattcc gtccgtggta
    52681 gttttacttg tttcgattgg ttcggcttcc ccactctctg gattttggtc atataatgca
    52741 aattcgactc cagccaacgg ctcgccattt tgacccttct tgctgacttg gaaattacgg
    52801 cctttatgtt cgtaacgaat ggaagaagat gggaaataca tccgtccagt agtgatatca
    52861 ttctcataat cctccaggtt ctgaatatag gccatattgt tcactgtgca aaaatttccg
    52921 tcttgagctc ccgcatcaag ttttacttgg tacttgatcc tgaccatttc cccttcacct
    52981 aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc
    53041 gccactactt ctggtggggc ttgtccatga cgttcttcat cccatatttc tggctcttgg
    53101 tacttcatgc cgttttctcc tggatctaga tggtaaaact gaatatctgc cgatctgcca
    53161 gctccaaatg gtgagacatt aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt
    53221 ctcttgaagg tagaagagat atcctccaag gctgtaacaa tgtcattctt gttgttcgca
    53281 ttgtaatatc gcggtgttac gccatcttct tctaaatcag caatattttt caatacattt
    53341 cgtccaatag catctagtcg ttgtctcccg ctaacgtttc catcgattcc taaaccaatg
    53401 gagaagatac ttggcgggtt ctcttgatac ttgtttttca gccaatgatg ataagcaact
    53461 gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc cattcgtatt gttattagaa
    53521 gaaccatcac caacccagtg agtcgcttta ttatctcctt cttttacctc tccataacga
    53581 tagtgtacat ttacttcatc ttctggacgg ttaaagtcag atgcataggt aactggatga
    53641 gtaaaccctg cattagaagt attcccagaa aactcctcaa aatttctgaa caaaacgtca
    53701 ttatcttcag caatcttatc ttccatcaca gtccagttgc tccaagctcc attagtgctc
    53761 gtacgataac ttgactgaat cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg
    53821 attaggattt tttctggatt tctattttct ccgccattgt ctttatacaa tgtttcatag
    53881 ccatttttaa gccctagtgt aagcggagtt cctccgattg gtgtacgatt taatgctgta
    53941 ttctcacttc ccgtcaaacg attgatatca tttgtcaatg gaaagatgtc cgaactgatt
    54001 tgctcatggt tattgatagc tgtactatta tggtaaaaat tcaccatacc gattcgaata
    54061 tccagactcg ggtcagagag cagatcttta ctcatttcgt ttactgcctc aatcaacgca
    54121 gcatttttag tttgactatt ggtcccagcg gttaattcac tcatactcgc tgacttatct
    54181 agaacaaaaa cgatatcgat tggactgatt tcctttttct cgcccccgat gacatctaga
    54241 tagacattgt aaagggttgt tgcatcttca ggatgtagat cagatgctgt gctgcttggc
    54301 agaacaggtt ctacccattt tttgatgtac gccccgttat aatccaagta actgttttca
    54361 aaattccgtt catttcccca aagctgaacg gtttgagctg gaacgtttct atcttcttcg
    54421 cctgcagttg atccattatt agtagcatag tcgtaatttc gccagttcgc tcccccgttt
    54481 gtataatcac tatcatcgat caagttctct ccgtcatatg gcgagccttt gtctccttga
    54541 tagcgttcat tgctttgtgt ccaatttcct aacacttttg tatagtcatt cgttgtaaac
    54601 ttcgggtagc gatgctgttc gttttcaact tctccgctag gatagatata ttcatagggg
    54661 tcttgcgtag ctgttggccc aagacgctcc aaaataccgt tgaataactg gcgttgaatg
    54721 cgctggagtg cttgaccgct gggtacgatt ggttcgtcca gcttttccat ctcattttct
    54781 tcgctacgtt gaatttcagc ggaatcttct gtatcagttt cattttcttg taattcttgg
    54841 ttatctattc tttcatcaac caccacttga agaggtagtt acccttcgtt cacatcgggg
    54901 atcttttctg tttcaaaaat caatgtgccg gtttctgctt cttttgaata aacttttccg
    54961 acataccatt cttgaccatc gatcgtctcg acttttaggt cttctccatc ttcatcatag
    55021 gaggatagac ctgttccacg aacgtttttt acggtaccaa tcccggcggc tgccgcatcg
    55081 attgctaaac gtattctacc ttcattggca ctttcctttt tttcaaaagc cagatgccat
    55141 tcaagggttt cttctttttc aatatacttc ccttcaattt ttgcatagtc ctcatctaag
    55201 aatacctcat cctcctttgt ttctgttgac tcagcagcta catccagggt cgtcatatga
    55261 tagactgact ggaaatatgg tccaaatagc aaactgacag ttactaactg caaaatcttc
    55321 aattttaacc ctttcacatc cttatactcc tttcaaaaat atttgtcttc tttcacaaca
    55381 atcaacaaaa caatgcccat ctaattataa tttaatttaa ttttaatttt aaatcaaatg
    55441 atatcctttt tagttaaaaa acaccaatta tacaacattt attattaaaa ttaaattata
    55501 aaattttata acgttctcat ttaacaaaac ttaagttatt aagacaaatg aataaacaac
    55561 tacgctttcc tcgaaacaaa aaaataaagc acaaatgcgc atttacgcac tcatgcttta
    55621 ttcgtacaat taattcagat aacggcagcg cataggatgc caataacact tcctaaaata
    55681 gctcctccta aaatgtcagt aggataatgt aaaagtaaaa aaatcctcga ataagcgatc
    55741 aaacaagcaa ataaaaaggc taatattcct gcaactggac ttaattcgaa caacgcagct
    55801 actgataaaa aggctagcgc tgtatgtcct gaaggaaaag aagaagtctt cggtttactt
    55861 gtgtaaagga caagccgacg atttttttca taaggtcttt tccgtcttgt cgtttttttg
    55921 ataaaaagca aaccaacaaa aaaatagatc aaactgccga taagaatggc tagaccatat
    55981 tctctagtat caggtatcaa gactaaaaca gcagcaagga gcaaccaaat aaaaccacca
    56041 ttagagatat tactgataaa tttcaaaaaa ttgatttttc gactatccgt tttccgttgc
    56101 ttggcgaact tgttgataat actatcatcg attttagcaa tcaaacgcaa catgttattc
    56161 ctccttttta agaacctttt cttgcgtacg atggataaaa agcaggactt gaaaataaaa
    56221 caagaaactg aaacctaata aagcaaaata gattggtcct gcaaaccaga atgcgacaag
    56281 aaggatcaac gtgcctgcca aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa
    56341 aaatgcagta atccaagaag cttctttttg ttccagttga agcaagattt tgtaactaaa
    56401 gagaagcgcg cttaatagaa gcaaaaacaa cgtagtatac atcaatgtat agccaattcc
    56461 cccaccccaa tagcggaaaa tctgataatc gatcaataga agaagaaaat aaacacttgc
    56521 taaactatct tgctttccat aaagagagaa gttctcacga aactttttcc agaatagtga
    56581 accgagcttt ttctcttcat tttttttgta atgataaatc atatacagaa ctgttcgact
    56641 tgcagttcct aatgtgaaaa caggcaagac gcacaggaac catagtagct gtaaatggat
    56701 aagacgtgga atccattcaa tgatttctaa gaaataatca ttggcttttt taccaatcga
    56761 tcgattcatc atccttttga acctcctgtc aaatccatcc cttcaatgaa ataacgttgt
    56821 gcaaaaaaga acagcaaaat cgtcgggatc aagacaagtg ttgctcctgc catcagataa
    56881 ttccattgtg tcgttgcttg gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt
    56941 tcttgatctt ggatatataa cagaggacct aagaaatcat tccaagctgc gttgaaggaa
    57001 ttgatcgcaa tggtaatcaa ggcaggtttc gtcaatggaa gcatcaaatg actccaaata
    57061 tacaaatgat tcgctccgtc gatttcagca gcttcgatca attcattatt gatcgataag
    57121 taaaattgac gcatcagaaa tatattgaac gcattgccga agaacgatgg aacgatcagg
    57181 ggcaaataag tacctaccca gccgatcttg gagaataata catattgagg gatcatcgtt
    57241 acaaaccccg ggatcatcat cgtagaaaga accaaagcaa acatcagctt tttcccagga
    57301 aaatcaagct tcgcaaatcc ataagcaata aaagaatttg aaaggacatt accgatcact
    57361 actagcacag tgatgaataa tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc
    57421 gtatccagat agttttccca tacgattttt tctgggaaaa aggtcggagg ataacgaacg
    57481 atttcttcca ttggtttcaa tgaagtaaac accatccaaa gcaatggaat gatcaaaatg
    57541 attcctatta ctgtcatgag gacataactt agtatttttt tgtttgccga ttcacactgg
    57601 tctttttgaa ataatccatc atttgccgtc acctccagaa taatagaccc acttaggtgc
    57661 aagcttcaaa ttgacaaacg tcagaaccaa cacgatcaga aacaggatca ttgacatagc
    57721 catcgcataa cccatatcaa aagctacgaa cgccttgttc cacatatgca gattataaaa
    57781 aagcaaagaa tttgcaggtc cgcctgttcc atttttcgtc atgacataag cttcttgaaa
    57841 aatttggaaa gaaccgatcg tagaggtgat cacatcgtaa aaaataatag gagtgattaa
    57901 tggcaaagta atacttttga actttcccca aacgcctgct ccatcgattt ctgctgattc
    57961 atataaagat ctaggaacat tttgtaatgt agctaagtaa agtagcattg ctcctccaga
    58021 actccatatt ttcatcaaaa tcaacgcagg tttcgtccat tgtggatcaa acagccaagc
    58081 tggtccaggg atatggaacc agcccagaaa tgtgttgatc aatcctgcag atggagaaag
    58141 cagctgcatc cataagatgt agactgctac tcctgataag actgccggta aatagaaagc
    58201 tgtacggaat acactgattc ctttgatttt ttgattgagt actgtggcta aaaacacact
    58261 gaaaatcgtc gtcagcggta cattgaagat gacgaaataa acggtgttgt ataacgattt
    58321 ccaaaataaa tcatcgtgaa cgaacattct tttgaaattt gctagaccaa tgaaattcat
    58381 cttggatgtc aaattataat cggtgaaact accaataact gaaaaaagca taggccctag
    58441 cataaatacc aagaacccga taataaaagg cgagataaat aaataggccc atcttgcttc
    58501 ttttttcttt cggatagata aacgcttcaa attttcttgc ctcctctgta cctagacagt
    58561 caaaaatgga ttattgattt tgcttgacta agttttctac tgctttttgt gcatctgcca
    58621 atccttcttt tggtgatttt gttcctaaaa gaatctggtc aatctgttca ttcactaatg
    58681 tcgtgtaatc cggagcatct aaaggaactg gtgtgatcac cgtattttta aagttttcgt
    58741 ccgccatttg atagatcatt tttcctttat ccgttaggtt gtcattattc actaaattct
    58801 cattggctgt cttgctcgcc atgatatcaa aacttttttc gccgaatttt tcttgtactt
    58861 ctggagaaga aagatatttg atgaattcat aagaggcctc aggatctttt gctccgtatg
    58921 gtacttccaa gacgaatccg ccaccccacg accaatggcc tgaaccttct tctttttctg
    58981 ggagctgcat cacgccaaaa tcaaaatcat ccggtgcatt ttccatcaaa ctagagtaat
    59041 aattgatatt ttgggcacgc atggctacta atccggaaat aaatggatca gatacaccag
    59101 acccaaattc ggcttctaat ttattgatcg tatttttccc ataataatct tgccagtctt
    59161 ggatccactc caaggcttcc actttatttt tagtatcaat cttgactttt tcatctttgt
    59221 caaaccaact agtcccgtta tctgcgttta gcgcccatac atcagcccct aaattccata
    59281 atggataaaa accgatgcgt gtaaattctt ttccttcttt tttatctagt ttacgtgctg
    59341 tttcttctaa ttcatcccaa gttgtcggta gatcttgttc actgattcca gcttctttaa
    59401 atatcttttt attataaaaa atgacttgtg tatctgtatt gaatgggatc gcataaggat
    59461 caccttcata ttctactgta tcccaaagct gcggataaaa atccttagaa gtgtcttttt
    59521 ctacatattt ggagagatta gttgcttgct gtgcttctgc tctttgggca acggaattta
    59581 tgtcctgtac aataacatcg ggtgcatttc cagctgttat tgcagataaa gatttagtcc
    59641 agatgtcacc ccatggctga tacttataat ttacatggat ctcgttttgt gattgattga
    59701 aatcctcaat gatttcttcg atagcttctt ttcgtgcacc ggatccccaa aaggaccaga
    59761 aatcaatatt ttttcttcca tcacttgttt tttcagaaga atttgctgca cttgaactgg
    59821 catcgcttgc attacttgat ccgcatcctc ctaataaaaa caatgctgaa cttgccagca
    59881 accctgtaaa caataatttt ttcatatttt acctccaaat tttaatgtaa ccgatgccgg
    59941 ttttaatata acgatatcat tttgttctga aaataacaat ttataaggta tgattctaaa
    60001 aaaattatta atgataccaa tactttatat aattcgcgag cgctttcttt gaatttttta
    60061 atctttcgta gcagaatgag aatgtattaa aaatagatta ggaggaattt tgatgtttag
    60121 acaccagaaa gaattgcagt ttgaagcaaa accagatcgt ccgaatccat taatcgcgaa
    60181 atatctgcag gagctgatcg gcggccaata tggcgagatg agtgtagcta tgcagtacct
    60241 gttccaaggc tggagctgcc gaggagaaga aaaatataaa gatatgctga tggacattgc
    60301 aacagaagaa atcggccacg tggaaatgtt ggcgacaatg gttgctcgtt tattagaggg
    60361 tgcgcctgtt gaagatcaag aagcagcgat gcaaaaagat ccaacaatcg gtgccattat
    60421 ctctggaatg aatccacagc acgcgatcgt agctggctta ggacctcgtc ctgctgacag
    60481 cgtgggcaat ccatggagcg gtgcctatat cattgcgagt ggcaacttgt tagcagactt
    60541 tagagctaat ttaaatgccg aatcacaagg aagacttcaa gtagcacgta tttacgaaat
    60601 gatcgatgat cgtggcgtaa aagatatgct gtctgttctc cttgcaagag atagctatca
    60661 tcaaaatcta tgggaatgtg cagtgaaaga attagaagaa aaagaaggtt caatcttagt
    60721 cccaagtact ttcccgcgtg acaaagaacg aaaagacatt gcttatgact tctataactt
    60781 ctcagaggga gaccaaagta gtgaaggttc ttgggctagt ggcaaagcac tggatggcga
    60841 aggcgaatat caatggttga aagaacctaa gatcgaaggc gctgcaccaa aattagaacc
    60901 agtaacacca aaaatgtatg ggacacctcc attcaagaaa taaatatcta cccgtagaaa
    60961 cacccgtttt ttgttccaca cgctttgtga gcaaaactga ctaaagtcat taatcataac
    61021 cacccttcaa aagggtggtt ttctctagag ctataagctc aaatcaccgg ccagcgccta
    61081 aagacgctgg ctttcatatt ttatgttcaa gccatattgc ctttgccagt tttgcccacc
    61141 tcttaaaagg tttatgtact actccttagc ccttaaaagg atcgtcttac tctcgtacac
    61201 tcagcttatc taacgcacta tcatgttttt cttgttcttg aatgtacttt ttgatggtcg
    61261 cttcattttg tcctactttt gtcacatagt atccttccac ccaaaagtgt cgatacccaa
    61321 atttatattt tagatttgca caatctcttg atgatctcct gaatattggc tcgatattga
    61381 ttataaatta tttttcttct atactttggt gtgaatacaa tgtggtattt acacatctac
    61441 tttgtacggg ctaaactatt tccctttatt gctccacccg catagcaagt ggttttgtat
    61501 ttcaatcgct cggcgcgctc aattaggtct aaagacaata aatctaaaaa cccgctgctt
    61561 cactgacaga aacaacgggt tttcagaaaa aaatgaaatg aaaaagatct cttacggcaa
    61621 tctattttat ttttttgatt ttttataaat ggaaaatgct tcaagaagtc caagaaataa
    61681 agccgtataa aaacaagaac ctatgaaatc tttatttatt agatattcaa cagaaatccc
    61741 gataacacta gccaacaata tatttatcag aagtgtaaaa taaggatgct ttttatagaa
    61801 tagaactagt gttgttttca tagactctcc tttcttcata tttccaatta atcacaaatt
    61861 cacggcatta ctagaaaaat taaaggggcg cagaagtgga aaaatactct tcgactttcc
    61921 ctacaaacca ggccatcttg tgtttaataa ctataccaaa tctaaggtac ctctaaatct
    61981 aaattccatt tgtggcggtg acctccaatt tttaactctt ctatctccca tccagtatac
    62041 ataaccttga tacttcgacc acttatatat cgaacacaca aatacctatc cattgcagga
    62101 gtactaccta acttagttgc tacttgcatc taaataacag ctgaaaagat aggacttact
    62161 cttagtaaag tatctgaact attaattttt aaactatcat ttttatcctc aactacatgc
    62221 acatctgttg caacttcact ttctgtctca tccagataaa tgattaagga atcgggaatt
    62281 gcaatatctt cagctgacgc tggaatagtt gagctaaatt agtcatcata tctttattat
    62341 aaaataacca acagcaaaaa atacaatgaa aaacaaactt ggaactaatg tatcattaat
    62401 aaatgttgaa aaattcagca actcattact gtatgatttt agcagcccaa ccaacatata
    62461 ccctataaaa gctaataaga tggttaggaa tcctttagaa tttttactca ttcatagaca
    62521 cttccttaaa taacttttat tatagaaggt attgtaaata ataatattga caaaaagtga
    62581 ctcaaaataa aaaaaacctt acattatact ggaatgaact gtattgatag tgtacctaaa
    62641 agctctactg acataagatc gtgtaatcgg taaagtaatt ttattaatta tacgggatgt
    62701 aatcaattag agaataaact aatcataaaa ggtactttta cattcataat tgtcgctttg
    62761 agattctact ttggttcact atctgaccca attgcacatt ttcgatcatt acaagtattg
    62821 gtgtcgttag aacaactaaa taaaaactag cggtagattt ttcagaatct atgctaattt
    62881 ctgtatggat gttccagtga tggcaaattt ctcttttcat tgtttttctt gtcgcatgat
    62941 atgccttttt gtgttattca gttaaactat agaaattctt tcctagacag atcttgatcc
    63001 caaattttac gtttttgagc atcgatatag tttaaaatga cattactcat atctaaagag
    63061 tttagatttt ttaggactaa aactgtcagt tgttcttttt cttctttctg ttaaagtatt
    63121 gtcgcgactt ttcgtatacg ttaagatatg tcgtgaaaaa acaagttttg tgacacaaaa
    63181 aaacgaatga cttgaggaaa tcacctcaat cattcgttta aaatgctata tattctttag
    63241 tttaagatac ggaaattaat gccatcgacc acactagtag aatgaacgac atttacttgg
    63301 ccttttttta atttcgttat gtttagcata taaaaatatt atagagttta cttacaatgc
    63361 ttaaaacata tactgtataa tctgatcaat tttagccatg tcttgcaatg gtaagttttc
    63421 tatttttttg agttttcgtt ccttaaaatc aagagatttt aattgtgtaa taattacttg
    63481 tccttttata tctagctctt caggtaatga gtaacgtgtc ggtaaattct ttatagtgga
    63541 agtaattgga catatgaccg aaaacattgt tttacggtta aattcataac gagagacgac
    63601 tagtcctggt cgtctttttt gaatttcttt tcctacggag ggatcaaaat caatccatac
    63661 aatatcacct tttttaggaa tataaattct ttcttctgac actataaaat ttctctccct
    63721 tcaggagtta aatcttccca ttcgtctttc tcataatact cggcctcttc cccaccacta
    63781 aatggatctt caatttttgg aactaacgta attgttccat catcagaata cacaacgata
    63841 tattcttggt tttctgaagg tttctttccg ttatcagaag gtaaagttac cactacagaa
    63901 cttccttgta atctagattt tgtaacaagc attatcatca ctcccttaat aaaagtatac
    63961 tatataacac taagtaacgc aaaattcccc tttgtaaact atctagaaaa ttgttttgtt
    64021 taaagtatat cttattggat ataaatagaa ataaattgta gccagttcat tttttcttta
    64081 actaaaaaaa taatccaaga aacattgaac ctatggatcc aaaagctacc caaatactat
    64141 agctaacccc ccgctacctt caattttgca gataaaacgc tttgggagaa aatttcaaag
    64201 acaacaggcc atcctatcat gcccgattat aaacaaaaag ctggctattc cttttgctct
    64261 gacaaatttc aattgggaaa gttcacgaaa ctagcaggtg aagaagtttc aactgttcgg
    64321 atcaaagaat gcccgcttca aatagaaaca ttggttcaac gaatttcaac tagacaagac
    64381 tttgctattg tagaacgtga gatcgtagct atttttgtag aagaagggat tttacatgat
    64441 ccaactcata tcaatgtgga taaatggcaa cctcttatct ataaattcag agaatataca
    64501 actgccaacc agtcgttaac tttgaatttt agattccaag aattcaaaga gtcataatga
    64561 taaacatcgt taggtataaa taaaaaagac tcgcagcacg agtaaaaaac aaatagaagc
    64621 tatacattag aaaggtcgac tgtgacccta tagatgcagt atatgcagct tatgagcatt
    64681 tcttctgttc tctttgtttt tgggatctgt gctgaagtct ttttcgtttt ttgccgctct
    64741 ttctttgaaa aatcgattat gttatacctt ctccattact aattcaggca tctgctgagt
    64801 aatgattttt cgcgcaaaag aaatatctgt tacccaaggt tcgatttgtt cttcagtcaa
    64861 gacaagcggc attcggtcat ggattggtgc gactgtgcgg ttaggttcag tagtcattat
    64921 gattgattct gccatttttt catcctgatg gctacgataa aaaccgccaa tatacactat
    64981 tttttcctta tttgaaaaca taaatttgtc tttttcttca ttccactcat tgggaaaaca
    65041 caacgatttt gcaaaaatgg ttgatgaaag gtcttttttt cttctactgt ctctgcacgg
    65101 gcattaatca tcaattgtcc ttttttaaat ccggtaaatc cccacttcat gatttccgga
    65161 gtgaggatgt tttcttcctc ttttcttaac gtcacaacaa gatttgacgg aaaaacttct
    65221 ccagctgcta attctgctgc ctgcttcggt tgtttcgtct gggcttctcg ataataattc
    65281 tgaaggagct ctgactctag atcaaaaaaa taacgaccac acatcctaat ccctcccaat
    65341 ctttttttct atcatacact gcaacaagaa gttcgcacca acaaaacgct ttcaattttt
    65401 gtagaactaa aaaagttgtg acaagtgaca aactctccag tgaatggtat tctcctgcca
    65461 actcctcggt cacaagtcac aatattcaac aaacatgaga agctgctttt tgaaattgtt
    65521 ccttgtgact cggagtgaaa cggcaggctt acgacctctg ggtaaacggt gttcaaaagc
    65581 cagtttctcg gtattaagcc aaatttatgc aaaaatgtag aaagctattt tcacaaaatt
    65641 tttcttaata ctcgaaacta agcgactttt tcacaacctc ttccttaaac ggtgttcaaa
    65701 agcttgcatc tgcggtaata agcccaacca aacgaaaaat atgagcagct atttttattt
    65761 ggctgttctt attacttgat gcagggcagc tttttcacaa cctctccact aaacggtgtt
    65821 caatcagcta accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    65881 gtttgtttct ctaatactca ggtcaaagcg ctgatttcac aacctctaat acacggtgtt
    65941 ccagaagtag cttcttcgaa aaataagccg aaatttcaca aaaatttgag aagcaatttt
    66001 cgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctct aattattaaa
    66061 gaaccttttg cgaagttaac aatctttctt tgatcaattg aaaattctgc ctaagtagtg
    66121 atagatcctg tgtgactttc aacaataaga tacttccctg gatttcagca atcaacgctt
    66181 tggcttgacg gtctgcttct tcatcggaca gtttttcttc agaaagtgcc aggatatttt
    66241 gtttcgtata cttgacccat tgattgacta attctagtag caacagacgg tattcttcat
    66301 ccactgtact caactcaata atcaaattac ctacaggaca gccatgataa gtgatctgtg
    66361 tctcatgatc agcgaaaatc cagtccaaca tttcttctaa tgcttcttct ggctgttttc
    66421 cagcatttaa gatgtcttcg aacaattctg tctgccatac gtccatatgc gcatggatca
    66481 ccgctagaca aacttctttt tttgaagaaa agtaataata aaattgacct tttcctgtat
    66541 cagaagctgc tagaatatct cggattgacg tttcatgata gcctttttta taaataagat
    66601 ctttggtcgc ttccaagatc ttttcctttg ttttcaatga tattctcctt tttcatttct
    66661 catagtccta tattatacag taaattcatc attttttctt cttaatcgtt taaaaaagac
    66721 tgtgccaaat tatctgacac agccctcact ataaaactgt tctcatatag ctagatgttc
    66781 attgattcaa gaactgcgag gacaaaagca attcctatct tatgatagtt gctctaatac
    66841 ttcctctgtt gtcatcactt gatctgcaat aaagccaaag ttcgtcaacg ctgcatccat
    66901 tgcttcttgg ccaggagcac caattgcatc tgtcgctacc acaacattga atccactctc
    66961 taccaattca cgcatatggg aatcgctaca caagtttccg ttcattccac caagaattac
    67021 tgtgtcgatt ccattttttc tcaattggag cgccaaatca ttgctttctg gtccaaagat
    67081 tttatgagga gagctgatga tcgtattttc atccaaataa ggtttcaatt cttcgataaa
    67141 atcggctcct gaaccttctt ccactgattc atattgactt tttctagcaa acatctgctg
    67201 ctcaagcatc atatgttctc ctgcaccgcc aaattgccat ttatggtcat gtgggtaaaa
    67261 ataatgagga gaaataaaga gtttgtatcc tttttctttt gcttgtttta ccatttcaat
    67321 catattttcg atcgtattgt atttttctaa gatatctttt gtcaaaccaa agccaccgcc
    67381 tgctggtttc aagaactcga cttgcgggtc agtgagaact actgctgtat ttttattatt
    67441 gaacatggtg gattctccat tcgttattta ttttaataca tcatttagag cttcactcat
    67501 tgtcggatga gaatagattt gatctctcaa taacgtataa ggaagttttc cattcatagc
    67561 tagcgaaatc aagttgatga cttcatgaga atcttccgca tagatacttg cccctagaat
    67621 caagtcagtt tcagggtcga ctaaaacttt gaatacacct ttaggatctt ctaatacttg
    67681 tgctttaggg acaccgcttg tcatatactt gaataatttg taattgacgc cttgtgcttt
    67741 ggcttgtttt tctgttaaac ctacattgga taaagtcgga gtgataaata cactgtaagg
    67801 cacagctttc cggttattcg ttgttcgttt attctcgccc ttcaactgat ccataatgat
    67861 tcgataatca tctagagaga tataagtgaa ctgcaatccg cctttgacgt ctccaatcgc
    67921 ccaaatgttg tctgcatctg tacgaaggta ttcatccaca gcgattgctc cgcgatctgt
    67981 tagtttaaca tctgtatttt ctaatccaag tgatgctgta cttggttttc ttccagttgc
    68041 agccaaaact tttgacgctt ggattgttac ttcttggcca tcttctgtaa aggtgacggc
    68101 agctgttgat tcttggtctg ctacttgatc tacagataca cctagatgga attcgattcc
    68161 cgcatttgtc atgtcttcta aaatcatttg cgcgatatct tcatcttcac gtggaagaaa
    68221 ttcagaatgg gcatcaagaa cgacaacttt agatccgtat tcattgaaca ttgatgcaaa
    68281 ttccaagcca atatatccag ccccgatgat cactaatttt tccggtaatt gttcctgatc
    68341 catcgcttgc gtagaatcaa tcaagtagcg acttgtattc aatcctttga ttggtaaaat
    68401 gattggttca gaaccagtat tgatgaaaat ccgttcgcct tcaacaatca ctttttcacc
    68461 attattcgtc acttcgattt gatggttaga aagaaaacgt gctgtaccgt ccatcactgt
    68521 cccagttgcc tcatcgctga tcatatgata atttttggcg cgaagcatgc ccgtcaattt
    68581 ttctttccga gcaacagcct ctgtaaagtc gattcctctt tctccattga aaatcaatga
    68641 tttagaagga atacagccga tgttgataca tgttccgcca tacatacgtg ttgacttttc
    68701 aacgactaaa accgattcac cttttgaagc taacgccttc gctaaagtct taccgccctt
    68761 tccaaaaccg atcacaatat tttgatattt ttccatcatt tttccctcgc ttctttttta
    68821 cctaccgatt ggtacaaaaa tatgataacc gataattgtc tattctccaa atcatctgct
    68881 ttatttgtca aaaaaaacca gacaaaaagc ggtcctttca cgtttttagt ctggttcgat
    68941 ttcctttatt cttctaaaca atcgttactt ctacatcgat atttcctcta gttgctttgg
    69001 agtaagggca gaattcatgc gcatcttctg caattttttg ggcttcttct tcgctgatgc
    69061 catcgatatg cacttctaat actacaccga tctgatagcc gccatcatct aaattataaa
    69121 gagagacacg tgcttttact gtggactctg ctgtcattcc tgcttctttg atcatatgtt
    69181 gtaccgcccc attgaaacaa gaagcataac ctgctgcaaa taattgttct ggatttgttc
    69241 cttctgcatg gattcctgga ggagtgattt tcatatgcat cgagccattt ggtgcctcga
    69301 cttctccatt gcgcccgcca tggttgatca ttgctgtttc gtatgctttt ttcattgtac
    69361 tgctcctttc gattgaccat ttgctacttg gctataatta tagtgtatga caagtaaggc
    69421 gctttctaca aaaattctgc ttattcgaat accagaatgc cgtcttctac tatttttcca
    69481 aaaaacaaaa aaatactact cgtgaacaac agcgtcatat ttgttccaaa ataaatagca
    69541 atcttttcta cataatcttt tatatgattg attttaagat acatatatac cagaaagttg
    69601 accccataaa ccaatactgt taaaaaaata accatattcg ttaccatttt ttcctccttt
    69661 tgctggtctc cctaccagca ctcgatttaa ccataccact ttttttgccg tccaagcaac
    69721 tagcctttca aaaagactgg tttattctgc tgttaatgat tcaagatcag aaaaatgtcc
    69781 gaataatttt gctaatttta ctaacgccaa cttgttcttt ccgaattcat cattttctat
    69841 ctgtaatact agtaacggct catgtaagct taaacggatc aaaaaccagc cgtttccgta
    69901 tggctcttct agatcatatc gaataccttc ttcattttcc gggtcgaagt tcatcccttt
    69961 ttcttcttcc aacagtcgct tcatttcttc taatatcttg tttccttgtt cgcgtggttc
    70021 atcgctgaac aattttaatc ggatttcttg tacttctacg ggctgtttca actctttgat
    70081 ttgttcatct aatgtgatac cttttctttt taattctggc aaaagcatca ggatctttgc
    70141 gatgacatat gcaccatcat ccagaaaata gttttccttg aatgcagcgt gtccgcttgt
    70201 ttcgatggct agctgtgtat ctttcccaag acggttaagt tctaatgctt tattgattac
    70261 atttcgatag ccggaaatat aacgaacttg gatgcctcct ttttcttcaa tgaatctttg
    70321 tagatgagaa gaagtagggg aattcgtcac gattcttgtt cctggatgct cttttaatac
    70381 gattgtactt aatactgcga tcaaattatt tcgattgatc actgttccag aagcactgac
    70441 aactgcagaa cgatccacat ctgtatcgaa aatgatccca agatctgctt catttgctaa
    70501 aacagcctgc ttgatacttt ccatcgcttc tttattatca ggatttggga tatgattagg
    70561 aaatcggcca tctggttcca aaaattggga acctgttgaa tccgcaccta agctattcaa
    70621 tactttttca gcaaagaatc caccagcacc atttccggca tcaacaatga ttttccaacc
    70681 atttagtggt ttgctttcta gtgttccaat ccccttttta atttttgtga ctaaatcttg
    70741 cgcataaggt gtcaaaaggt ctgctttttc tacgcttcca gtttgttcgc tttttatttt
    70801 ttgctgctgt gataggataa aagcaatatc ttctttttct gctcctcctt ctgaggtaaa
    70861 gaattttatt ccattataat aatagggaag atggctagca gtcagcataa ccgcagcatc
    70921 gcacgagaac tgttcaaatt gagtggacat aaacatagca ggcgtagtag ctaattcgaa
    70981 atcgatgaca tgtatccctt gttctttcag actttggatc aacgcctctt tcagtgctgg
    71041 tccgcttatc ctactgtcat gaccaatccc aatcgtccat tttttatttg gatcggttga
    71101 tttcttcttt ttctttatcc agtttgctag tccccagccg atctttttta ccatgtctgt
    71161 cgtcaagttt acttcatatc cttcaactgg taatgcgatt cctcgaatat ccgatccatt
    71221 ttgcagcgct ttcatatctt tcatataaaa gtcctcctca tttattccct cattttttcc
    71281 agcttttctg caaatcgctg tgcttcttct tctgagcggc aaataataat gaatgtatct
    71341 acaccggcca tcgttccgac aacttcaggg taagccactt catctagcca attcgttacc
    71401 acatcggcac catttcgttc agtcaatacg ataaccatga actgaacaga ctggatacgc
    71461 aaaacctcgc gtctaattgc tgtacgcaaa cgttcttcat ttaaagaaac agatggctgg
    71521 ttaaataatg tatagcgtac tattttgttt tcattttgac tttttactaa cttcatttct
    71581 cgaatgtctc gagaaatcgt tgcttgagtc acatcggcgc ctgcttcatg cagccgcgca
    71641 agcagctctt cctgtgtccc aataggttgt tctgtaatga tctggcggat cagtgcttgt
    71701 cgctgtttct ttttcatatt agacacctct caatgttgat tatagcaaaa gataagtaat
    71761 atttcttcat attttggtat tttttacttt tattttttgt tttcattcag gttgctaacc
    71821 tttttctatt ttaacacgca aaatcgtctt cattttttca ggtgctgatt ttcttggatc
    71881 gctgatgtaa atctctttgt gttctttaga agctctttca tagccttctt ttgcgatgaa
    71941 tgcttctaat ttctcaaacg ttgctggttc ttcggcatag ggcccgacgt gtaagatttg
    72001 ggcacaaaga ccttcttcca tctttttgaa tactacttgt tctttcaagt cttccggaag
    72061 tttgctagaa cgctgaatgg cttcttgtgc tatcgcttct gtaacaaagt caggctgtcg
    72121 gatcatcaat tgataagaaa aatgttcttt tttcatcact ggttcatgca aatacttttc
    72181 ttgcagtccc cattgtcctt ccagtggata gacagtatac atctgataat caggaatcag
    72241 ccaatttttt ttaggcgaca tgcgtattgc atagctgact gcatatagac aggctactct
    72301 tcgtttaaag tcttcctgat tcgggtcgcc gatccctctg atgctaaaga atgatttttt
    72361 aggaacctct agtatttgcg ggcttttttt catactatag ctcttgtctt tacgccattc
    72421 aattttttcc atttttcttc ctccgcgaaa ttccatttag ttatttatta tcatacctct
    72481 ttttgagtga cttggctaat cgtgttgaca ctatttttca gtttgtgcta gaataagtga
    72541 agtaaataaa tcgtacagat aacacgtttc ggcgtgtcga gagagaggcg gtttctattt
    72601 ttataataga aatcactctc tttttttacg aaatttttta gaggtgatgt aaatgacaaa
    72661 acaaaaacag ctgcttttag tacctgcagt aattgcaaca gggatgatgt cttttgcggg
    72721 cgtattgatc gagacggcca tgaatgtaac tttcccaact cttatcagac agtttgattt
    72781 aacgactgca caagtccaat gggtaacaac gatttatctt ttgatgattt cgatcattgt
    72841 tccgctgtct acttatttga atcgcaattt tagtctcaaa aaactctttt tagcttcaaa
    72901 tctgcttttc ttggcaggta taatgatcga tttcttctct cctaccttca tggtcctatt
    72961 gtttggtcga ttgctccaag gtgcagcgac aggtatcgct cttccgttga tgttccatat
    73021 tatcttgaca tttgcccccc tcaatcgacg aggcgcgatg atgggtgtcg gtactttgac
    73081 aacggccatt gctccagcaa ttggccccac ttatggaggc attatgactt cacattttac
    73141 atggaatcat atcttcctgt ttcttgtgcc cgttttgttt ctttctttga ttatcggctg
    73201 gtttgctatt cccgagatgg cagtacaaaa aagtggttat ttggattgga taagcgtttt
    73261 aggaatttgt cttttgttta gtggaagtct aacatttttg agtacgttgg gaacagtttc
    73321 cagctggatt gctttaatca tcggcggtat tggctggttc cttttttact atcgaagtaa
    73381 aaaagtggag catccactga tccgactgtc tattctttca aataaaacat tccgcttgtt
    73441 tttgattggc ttcttagttt atcagttttt attacttggt gtatcttttg tcttgccgaa
    73501 tttccttcag atcgttcaag gaagtagtcc ttttgtcgct ggattagcga tgcttcccgg
    73561 cgcagcggtt ggtgctttgc tttctccttt ttccgggaaa atgctggatc aatatggtcc
    73621 gaagaagcca atttttgctg ggctgattct ttctttgatt ggttggctag cattattcct
    73681 actcatagga cacgcttcag tgggtgtatt gattgcttgt catgtgtttt atatgatcgg
    73741 tatcggatta tcttacagca atatgatgac caccggaatg aatgcactga atgaagaact
    73801 acaaggagac gggaacgcaa tgttcaatac cttgcagcag ttttctggcg ctgtggctac
    73861 ttcattagta gcggtcatta tcaattacgt ccagcatcat acttcccata actatgaagt
    73921 gtctactaca ttaggatcaa aagcagcatt aggcgtcttg ttgctgttgc ttctcgtaag
    73981 ctttgctcga ttcgcctatt atctgttctt tgctaaaaaa gcgtagattc catatacggc
    74041 aggtgttgca tctgccgttt ttttgtgtga aaatggttgt ttgtaaaagg aggctttttt
    74101 atggaaaaaa ttgccattat cggtggcggg atcattggta tgaccctagc cagttactta
    74161 gatacatcaa aattcaatgt tgctttattt gatgaaggga caggacaggc aactaaagct
    74221 agcgctggga ttatctcccc ttggttgtcg aaacgcagaa acaaacaatg gtatcgtctg
    74281 gctaaagacg gcgctgcttt tttccctaaa cttataaaag atttccaact tgatcaaacg
    74341 atttacgcac aatcagggac acttttgctt cgacctgaaa aagatttagc tgaattggct
    74401 gttcttgccg agaaacgaaa agaagaagcg ccagaaattg gaaacatcga atggctttca
    74461 cctgaacaga catctcaagc acttccgtta ttgaaaccag cagtttcact gcgtatcagt
    74521 ggtggtggtc gtctggatgg aaaagcatat ttagaacatc ttggtcagcg tttagcacaa
    74581 aaacaaatgg agcagatcca ggcaaaagtc actttgcata agaagagcga ttcttggctc
    74641 atcaagggac cgtttggaga atacacagct gatcgtgtaa ttttgacacc tggcccggca
    74701 cttaagcctt tattacaaga attaggctat gctgcagata tacgtccgca aaaagggcag
    74761 ctcttagcat ttcagacatc ttataagatg agtcaagact ggcctgttgc tatgcttgac
    74821 ggagaagctg atttcattcc tttcatggat ggaaagatcc ttttaggtgc tacccatgaa
    74881 aacgatcaag gctgggattt ggctcctact agcgaagctt ataagggatt gactaagagt
    74941 acagaacagt tcttgactga tccagatcag ataaaaaact ggccatacga gttccgtgta
    75001 ggtacccgtg cttatacgtc agatttttcc ccatttttcg gcgtactgcc agatgatcca
    75061 agcttactgg ctgctagcgg tctaggctct tctggcttga ccacaggtcc ttatatcggc
    75121 tatctattag ccaacttctt aaatactggt cattggccta cggaagatta tcaaaaggac
    75181 atctccacct atattacgaa aaatccatca tagaaaaaca gctttttcaa gtaaggatcc
    75241 cgagcgatat tgcgcatgga ttacttcttg aaaaagctgt tattttagtt caatttctga
    75301 atcaaattct ccaaactttc ttttgcttca tctggcaaga gatcttttcc tatctgagct
    75361 tcaatgaatc gtaaacgaat atcaagtcgt tgtttcacca gatttttata ggacgtatcc
    75421 tcaaaagaaa caggaaaatc tggtataggt aaatagtgga tgtcttcaaa tggaccaaac
    75481 gacttgaatt ctgccgtttg ttgcacgatt ctttcaacga ttgacaatgt cgtttcaggt
    75541 ttgatttttt tatcatcgaa atatccagta ttcaggacat agcaggctgt ttgctgtttc
    75601 aaaaacaact ctcgaaaagc ttgatagtct tccctaagag gatagacacg gaaaggatta
    75661 gcaaatggtt caatgactag ctcatctagc tgtctttttg tagtgatatt ttccgcgtct
    75721 gatcgttttg ttgctaatgt tgcaccaaaa gacgctgcta aaactgggtc attgatcttg
    75781 ataattggcg gaagcgaatc atctttcatg atccaaaaaa cagcatcgat cttttcgcta
    75841 agatgatcga ctcggtcggg tgtcgcataa cgtgatttga ctgtccgccc atttccgttt
    75901 cgtatatctc ctgttactag gactttttct cctttacttg tacatgtcac gcccacattc
    75961 tgacaagtaa ggaaagaaga aatggccgga tcatcagacg gatagtcttg tgttttatca
    76021 aagtaagaag gttccaaggc agtagcaaaa ccattttttc gagaaataac gaaagcatcg
    76081 tcatgcaaga tcgaaacaga gtgaccttcc gtatgttttg ctaaggtaat cgttgatttt
    76141 ccagaaccgg acaacccaaa tacagccatc gtataggtct ggtcattact agcatattgt
    76201 ttcatcccac cgtggcaggc aataaagcca ttgcgatttc ccaatgccca agcaagcgtc
    76261 aaagtcgctt tttttaattc tccaaagtaa cgtaatccta gcacagccgc tgtattatgg
    76321 agagcatcaa acaaaatgag tccatttgga aatgtttcat gtgtccattc gggatcacaa
    76381 aagatataaa gatctccctc atcaaaggaa acagactttt gataagtctc taagatcttc
    76441 gaattcgctg gctgaaaatt cagcaaataa gaatacaaat tgttctcaaa tccttctgga
    76501 atcagcaaat gactttgcac agaaaattct tcagataggc caacgattac ttttgtatgg
    76561 taaaactggc gcttgcgact ttgatacaca gcttctctta aaattttctc gtatttgctt
    76621 tgttccttgt ctaagtcctc aaagatccgc cgagcacttg ctgttcttcc cacaatgctt
    76681 ccatcattga atactagtgt cctaacatca gctggtaaat ctagttcttc agcatgtgag
    76741 attgttaaat ctgtgatgat cgttcctgga ctcccttttg ctagttgata agctgtcttc
    76801 ctatcaaaaa cttcatgaac attattaccg taaaatgtcg tttctacaat cgatcgaata
    76861 ctggataaca gtggatttcc acttgtgatt tcgtttaatt cgagactctc ttttgtactc
    76921 atggctcctc ctcattccct aaacaaaaaa acgttttctt tattatacat tattcgagtt
    76981 tttatttgta ctgctgcgct gtgggaagca aacgagttat ttttcacaca aaaaaaccga
    77041 gaacttgaat aaacaagttt ctcggtttca tcattttcct tttatcggct tagtaccagc
    77101 cgtttgctaa ccagaatgtt ttagcagcat cccatgaacc ataacgagat gttacatatt
    77161 gttctgctac acgttcttga ttggcagctg aatagtcgcc gtttaagtat gaagcatcta
    77221 attgataacg gccgatgtaa cgtccgttag tagctgtgta tgaaccgcct gattcttttt
    77281 gtgcgatcca ttcttttgca gagcttgaag ttggcgctgt tgcagcagct ggggcagcag
    77341 gagctacttc aactgtttca acaggtgcaa cgtatgtatg ttcttgcgtt gctgtttcag
    77401 ttgtagatgc tgtattttct gttgttttgt tttctgttgt tgctgaagaa tcatttgaag
    77461 ttgggattgt taattgttca ccaacataaa tgcggttgat gtttgcgatc gaattttttt
    77521 cagcaattgc atcgatcatt gagttgtctc ctgcaaattt ttgtgagatc ttagataatg
    77581 aatcacctga ttttactgta taaacttcat cagcgtgagc atttgtagtt cctacaaaca
    77641 ttgcagtagc accagcagca aaagttgtac ctaaaacaat tttcttaaat gaattcatat
    77701 taaactcctt tttttctccg ttttttattc tttcgacgct attaacttta tcatttagaa
    77761 atatttcata ggtaaaagaa acatgacatt taatgacaaa ataacgaatt atttaatatt
    77821 tgtaacattt aaacaaatat ttttttgat
//
LOCUS       DAZKNV010000006        73272 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000006 DAZKNV010000000
VERSION     DAZKNV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.006"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            425..811
                     /locus_tag="ACG8M1_000421"
     CDS             425..811
                     /locus_tag="ACG8M1_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0421165.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            905..1096
                     /locus_tag="ACG8M1_000422"
     CDS             905..1096
                     /locus_tag="ACG8M1_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421166.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            1610..1942
                     /locus_tag="ACG8M1_000423"
     CDS             1610..1942
                     /locus_tag="ACG8M1_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0421167.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            1852..2046
                     /locus_tag="ACG8M1_000424"
     CDS             1852..2046
                     /locus_tag="ACG8M1_000424"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0421168.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            2085..2231
                     /locus_tag="ACG8M1_000425"
     CDS             2085..2231
                     /locus_tag="ACG8M1_000425"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421169.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            2669..4009
                     /locus_tag="ACG8M1_000426"
                     /pseudo
     CDS             2669..4009
                     /locus_tag="ACG8M1_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4250..5866)
                     /locus_tag="ACG8M1_000427"
     CDS             complement(4250..5866)
                     /locus_tag="ACG8M1_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFQ0421170.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            5984..6202
                     /locus_tag="ACG8M1_000428"
     CDS             5984..6202
                     /locus_tag="ACG8M1_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421171.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            6397..6858
                     /locus_tag="ACG8M1_000429"
     CDS             6397..6858
                     /locus_tag="ACG8M1_000429"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0421172.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(7051..7290)
                     /locus_tag="ACG8M1_000430"
     CDS             complement(7051..7290)
                     /locus_tag="ACG8M1_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421173.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(7314..8837)
                     /locus_tag="ACG8M1_000431"
     CDS             complement(7314..8837)
                     /locus_tag="ACG8M1_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFQ0421174.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(8855..8977)
                     /locus_tag="ACG8M1_000432"
     CDS             complement(8855..8977)
                     /locus_tag="ACG8M1_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFQ0421175.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(9007..9990)
                     /locus_tag="ACG8M1_000433"
     CDS             complement(9007..9990)
                     /locus_tag="ACG8M1_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFQ0421176.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(10014..10163)
                     /gene="rpmG"
                     /locus_tag="ACG8M1_000434"
     CDS             complement(10014..10163)
                     /gene="rpmG"
                     /locus_tag="ACG8M1_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0421177.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(10184..10561)
                     /locus_tag="ACG8M1_000435"
     CDS             complement(10184..10561)
                     /locus_tag="ACG8M1_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421178.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(10593..10772)
                     /gene="rpmF"
                     /locus_tag="ACG8M1_000436"
     CDS             complement(10593..10772)
                     /gene="rpmF"
                     /locus_tag="ACG8M1_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFQ0421179.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(10787..11056)
                     /gene="rpsN"
                     /locus_tag="ACG8M1_000437"
     CDS             complement(10787..11056)
                     /gene="rpsN"
                     /locus_tag="ACG8M1_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFQ0421180.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(11579..13345)
                     /locus_tag="ACG8M1_000438"
     CDS             complement(11579..13345)
                     /locus_tag="ACG8M1_000438"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421181.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(13305..15059)
                     /locus_tag="ACG8M1_000439"
     CDS             complement(13305..15059)
                     /locus_tag="ACG8M1_000439"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421182.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(15169..15738)
                     /locus_tag="ACG8M1_000440"
     CDS             complement(15169..15738)
                     /locus_tag="ACG8M1_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFQ0421183.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(15756..17171)
                     /locus_tag="ACG8M1_000441"
     CDS             complement(15756..17171)
                     /locus_tag="ACG8M1_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421184.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(17182..17850)
                     /locus_tag="ACG8M1_000442"
     CDS             complement(17182..17850)
                     /locus_tag="ACG8M1_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFQ0421185.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(17980..18564)
                     /locus_tag="ACG8M1_000443"
     CDS             complement(17980..18564)
                     /locus_tag="ACG8M1_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0421186.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(18895..19128)
                     /locus_tag="ACG8M1_000444"
     CDS             complement(18895..19128)
                     /locus_tag="ACG8M1_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFQ0421187.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(19143..20093)
                     /locus_tag="ACG8M1_000445"
     CDS             complement(19143..20093)
                     /locus_tag="ACG8M1_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFQ0421188.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(20090..20932)
                     /locus_tag="ACG8M1_000446"
     CDS             complement(20090..20932)
                     /locus_tag="ACG8M1_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFQ0421189.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(20934..21653)
                     /locus_tag="ACG8M1_000447"
     CDS             complement(20934..21653)
                     /locus_tag="ACG8M1_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421190.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            22201..22503
                     /locus_tag="ACG8M1_000448"
     CDS             22201..22503
                     /locus_tag="ACG8M1_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421191.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            22575..23801
                     /locus_tag="ACG8M1_000449"
     CDS             22575..23801
                     /locus_tag="ACG8M1_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0421192.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(23889..24281)
                     /gene="rpsI"
                     /locus_tag="ACG8M1_000450"
     CDS             complement(23889..24281)
                     /gene="rpsI"
                     /locus_tag="ACG8M1_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFQ0421193.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(24297..24725)
                     /gene="rplM"
                     /locus_tag="ACG8M1_000451"
     CDS             complement(24297..24725)
                     /gene="rplM"
                     /locus_tag="ACG8M1_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFQ0421194.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(25259..25726)
                     /locus_tag="ACG8M1_000452"
     CDS             complement(25259..25726)
                     /locus_tag="ACG8M1_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFQ0421195.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(25846..27384)
                     /locus_tag="ACG8M1_000453"
     CDS             complement(25846..27384)
                     /locus_tag="ACG8M1_000453"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFQ0421196.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            27464..28150
                     /locus_tag="ACG8M1_000454"
     CDS             27464..28150
                     /locus_tag="ACG8M1_000454"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFQ0421197.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(28351..28878)
                     /gene="msrA"
                     /locus_tag="ACG8M1_000455"
     CDS             complement(28351..28878)
                     /gene="msrA"
                     /locus_tag="ACG8M1_000455"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0421198.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(28962..29639)
                     /gene="pgmB"
                     /locus_tag="ACG8M1_000456"
     CDS             complement(28962..29639)
                     /gene="pgmB"
                     /locus_tag="ACG8M1_000456"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFQ0421199.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(29636..30766)
                     /locus_tag="ACG8M1_000457"
     CDS             complement(29636..30766)
                     /locus_tag="ACG8M1_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFQ0421200.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(30766..32949)
                     /locus_tag="ACG8M1_000458"
     CDS             complement(30766..32949)
                     /locus_tag="ACG8M1_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFQ0421201.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(32946..33971)
                     /locus_tag="ACG8M1_000459"
     CDS             complement(32946..33971)
                     /locus_tag="ACG8M1_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0421202.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(34016..34843)
                     /locus_tag="ACG8M1_000460"
     CDS             complement(34016..34843)
                     /locus_tag="ACG8M1_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0421203.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(34840..35907)
                     /locus_tag="ACG8M1_000461"
     CDS             complement(34840..35907)
                     /locus_tag="ACG8M1_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFQ0421204.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(35933..36769)
                     /locus_tag="ACG8M1_000462"
     CDS             complement(35933..36769)
                     /locus_tag="ACG8M1_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0421205.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(36766..37635)
                     /locus_tag="ACG8M1_000463"
     CDS             complement(36766..37635)
                     /locus_tag="ACG8M1_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0421206.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(37705..38988)
                     /locus_tag="ACG8M1_000464"
     CDS             complement(37705..38988)
                     /locus_tag="ACG8M1_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0421207.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(39002..40687)
                     /locus_tag="ACG8M1_000465"
     CDS             complement(39002..40687)
                     /locus_tag="ACG8M1_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFQ0421208.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            40962..41987
                     /locus_tag="ACG8M1_000466"
     CDS             40962..41987
                     /locus_tag="ACG8M1_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0421209.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(42582..46235)
                     /gene="rpoC"
                     /locus_tag="ACG8M1_000467"
     CDS             complement(42582..46235)
                     /gene="rpoC"
                     /locus_tag="ACG8M1_000467"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFQ0421210.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(46314..49931)
                     /gene="rpoB"
                     /locus_tag="ACG8M1_000468"
     CDS             complement(46314..49931)
                     /gene="rpoB"
                     /locus_tag="ACG8M1_000468"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFQ0421211.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            50659..51627
                     /locus_tag="ACG8M1_000469"
     CDS             50659..51627
                     /locus_tag="ACG8M1_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0421212.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            51645..52550
                     /locus_tag="ACG8M1_000470"
     CDS             51645..52550
                     /locus_tag="ACG8M1_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421213.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            52547..53353
                     /locus_tag="ACG8M1_000471"
     CDS             52547..53353
                     /locus_tag="ACG8M1_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421214.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            53510..54478
                     /locus_tag="ACG8M1_000472"
     CDS             53510..54478
                     /locus_tag="ACG8M1_000472"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFQ0421215.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(54795..55319)
                     /locus_tag="ACG8M1_000473"
     CDS             complement(54795..55319)
                     /locus_tag="ACG8M1_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFQ0421216.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            55606..57303
                     /gene="scm"
                     /locus_tag="ACG8M1_000474"
     CDS             55606..57303
                     /gene="scm"
                     /locus_tag="ACG8M1_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFQ0421217.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSS
                     TTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDN
                     RTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(57458..58444)
                     /locus_tag="ACG8M1_000475"
     CDS             complement(57458..58444)
                     /locus_tag="ACG8M1_000475"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFQ0421218.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(58467..59033)
                     /locus_tag="ACG8M1_000476"
     CDS             complement(58467..59033)
                     /locus_tag="ACG8M1_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFQ0421219.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(59047..59463)
                     /locus_tag="ACG8M1_000477"
     CDS             complement(59047..59463)
                     /locus_tag="ACG8M1_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFQ0421220.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(59920..61854)
                     /locus_tag="ACG8M1_000478"
     CDS             complement(59920..61854)
                     /locus_tag="ACG8M1_000478"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0421221.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            62156..63091
                     /gene="pplA"
                     /locus_tag="ACG8M1_000479"
     CDS             62156..63091
                     /gene="pplA"
                     /locus_tag="ACG8M1_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFQ0421222.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            63181..64284
                     /locus_tag="ACG8M1_000480"
     CDS             63181..64284
                     /locus_tag="ACG8M1_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFQ0421223.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            64297..65250
                     /gene="menA"
                     /locus_tag="ACG8M1_000481"
     CDS             64297..65250
                     /gene="menA"
                     /locus_tag="ACG8M1_000481"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFQ0421224.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(66064..67410)
                     /gene="gor"
                     /locus_tag="ACG8M1_000482"
     CDS             complement(66064..67410)
                     /gene="gor"
                     /locus_tag="ACG8M1_000482"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFQ0421225.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWKASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(67544..68797)
                     /locus_tag="ACG8M1_000483"
     CDS             complement(67544..68797)
                     /locus_tag="ACG8M1_000483"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFQ0421226.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(68803..69726)
                     /locus_tag="ACG8M1_000484"
     CDS             complement(68803..69726)
                     /locus_tag="ACG8M1_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFQ0421227.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(69947..72439)
                     /locus_tag="ACG8M1_000485"
     CDS             complement(69947..72439)
                     /locus_tag="ACG8M1_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFQ0421228.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(72446..72913)
                     /locus_tag="ACG8M1_000486"
     CDS             complement(72446..72913)
                     /locus_tag="ACG8M1_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFQ0421229.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(73049..73122)
                     /locus_tag="ACG8M1_000487"
     tRNA            complement(73049..73122)
                     /locus_tag="ACG8M1_000487"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(73086..73088),aa:Arg,seq:acg)
     gene            complement(73180..73253)
                     /locus_tag="ACG8M1_000488"
     tRNA            complement(73180..73253)
                     /locus_tag="ACG8M1_000488"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(73217..73219),aa:Pro,seq:tgg)
BASE COUNT        22049 a        14945 c        12602 g        23676 t
ORIGIN      
        1 cgtttctaaa tattccaatt tgggaatcca ataaaaattt tcgttcaaat acgtgtctat
       61 tcgaactctt ttctagttgt taattatgaa gggggaagaa ataaaaaata caatctatac
      121 acgaataaga atattatcca aaaggaggtt ttagaaaaga tttattatac gtaaaaagct
      181 caagacattt tcttagccat aaggacatgt ttgatattta agaagatata tgaattttct
      241 tttctaagta taaagataac tatccattat caactaaaaa aacatttttg aaaataaaca
      301 tcagcagtcc tatcaatgca tgtgagctta tagaagttat tcgcagcgca gcataattgc
      361 attagcttct tttcgtgttt tttgcctctt ttccctttaa atcttaatgg aggaggtgtg
      421 caatatgtca gataacgacg aacgcgtaaa tgcccagttg attcgattct ttgaaaaggt
      481 cattttgaac accgctaata cttattataa aaaacaagaa gaaattcaaa aacatgaaca
      541 acttgatcaa ctcccaccat atttgtttac taaagatact ataaaattta aacaaccgat
      601 taatgtttta aatgtgactc tccttgttga agatataaaa ttagcaaaaa tccttccttt
      661 gttgaaagaa cctgaacaaa tttttcttat cgaaaaattt atctttgata aaactgataa
      721 agaaattgga aaggttctgg ggattacaag acagggtgcg acaaatttaa aacatcgact
      781 ttacaaaaaa attcaaaaaa tgctggttta atatctgcat aataactaat tttgtatgct
      841 tctttgctcg ttctcctcct tcccaaagaa atagattata agtccatggg aagaaggtag
      901 atttatgaat tctttaaaag aagatttcat tttagcaaag gctggaaatg aagaagctgt
      961 tgaggcaatt ctcaaaagat ttagctcttt gattcataag caatcctgga gaactggaaa
     1021 atatgatcaa gattgttatc aagaatgtat gcttgcaata tatctagcta tctcgaaatt
     1081 cgaaattaaa gaataactca actaagggag tctgtgacat aagtaaaaag atagtttcaa
     1141 atttcgaaca ataaatttga aactatcttc tttataatta taaagtatcg attttacagc
     1201 gttctataat gattcataga atctaaaacg aatgatttta attatcaacg ttttttaatt
     1261 cgtttttagc ttaaaaataa cttttgtcac agtctcactc ctaaaattac tttatttacg
     1321 tatgaagtgg gcaggaggtc gaatccagaa ctgggctatg gtacttcaac gaggacttct
     1381 cctctagaat tgaaaagcat gcgatttacc ttccgtaacg acggtagatt tattcaacta
     1441 tgtgtccaat caaaatttgt ctgatttcaa aaatagtcaa gagaattttg gttgttaaaa
     1501 actcttatct atcaacttcc acagtttagt tgacaaaccc tgatactaag ttgggctatg
     1561 atacactttt cttgactatc agttacgtta ccggaaggaa tgaactctat tgagaaaaac
     1621 atatgatcgt aaatttaaac taaagatttc acaggatatc cttgagaaaa aagtaactac
     1681 caagaaaatt gctgaagaat acaatatctc tcgtccaaca atttcccgat gggtttcaga
     1741 atatcgtcga tacgggaaaa atgcttttgc tggacaagga aaaagattac ctgataaagc
     1801 agatttctac attcttgaac aggaaaataa acgactaaaa gaggaagacg agtgttctac
     1861 gaacacaaag atcgatacgg atctccaggg atcactcaaa aactttacga tgaaggaatc
     1921 gaaatcaata aacgtgttgt agctgttctt atgcgtgaaa tgaatttatg cacaagagga
     1981 tttcatcgac gcaaatcttc tcatggtaga gaaaaaacaa tcaaagaaat ggtaaaaaaa
     2041 tgttgaatcg ataatttgaa cagaaccaaa ttgatgctgt ttgggtgatg gatattactt
     2101 acattccatg taatgacggt cgcctctatt tgtccaccta tattgactta gcaactcgta
     2161 ttctacgtta ctatatggta gattcacaca tgaaaaaaga gattgtcgtc cgtccattac
     2221 aaatttatta aggagaattg cctacggtaa ttcattccga tagaggtagc cagcatcggt
     2281 cttttattta tcaagagctg ttgaacgacc accacatcac acattcagtg agccaaactg
     2341 ggactcctgt tgacaatgca gtaattgaag cgtttcatcg atcaatcaaa tgagaattaa
     2401 tcgactccaa caaatataaa agtaaaatag agatgaaggt gttaatccaa gattatttag
     2461 aagactacta cccaaacaaa agaatccata caaaatttat gatgactcct tgacaatttg
     2521 aagcgaagaa aataagggat ctataatatc tagtgttggt gacgccttct gttgccaata
     2581 ctttttcttt tttctaataa acgcaaacag acaccttaaa atcctttaga ataaagtcga
     2641 cgaaaaccat tcaaaggagt gtttcaagat gtcctattca gagtttacca aagagttact
     2701 agatattcta gacctaaatc ttatctttca tgaagatgcc tttcgcaaag agcgaatcaa
     2761 tgacgaaaca tgttttgttt ttgatggcac attgacctat caaccggagg aatgctttca
     2821 tcgccactat caaaatgaac aaacgatcat taaatagggc tggaaaaaag tatccatctt
     2881 attgaatgat gtcagtaact acaagaccat tctgcggatt aacaaacagc gcttcaaatg
     2941 taaacactgt ggaaagactt ttttagcaga agattcagtt agtgatcgtc gctgctccat
     3001 tgctcgcaga gtcaaacaag ccattcttga gctattaagc gaacctcttt ctatgtcttt
     3061 gatcgcacgt atgaagcaca tttctccgac cactgtcatt cgaatacttc gcagccttcg
     3121 gcctaaaacc atttctttga gccagctgtt accagaagtg gtgtgtttcg atgaattcaa
     3181 atcagtgaaa aatgtctcgg gagccatgag ctttgtcatg atggacggca agacccatca
     3241 actgattgat attgtggaaa atcggcaact caatccttta cgcgactatt tcttgcgcta
     3301 ccctataaaa gtccgtgaac aagtgcgtct agtggtttca gatttctata caccctatcg
     3361 cacattggtg aaagagtgtt ttccgaatgc ccgaatcgtc gccgatcgct ttcatattag
     3421 ccaacacatt ggtcgggctt ttaccaacca ccgaattcaa gtaatgaaga cctttaaaaa
     3481 aggggatcgt cggtcgaagc acttaaagaa atactggaaa ctacttcaaa agaatgcgtg
     3541 ggaattgaaa ggtcagcatc gctactggcg tccgtcattt cgagatcatc tgacagaagc
     3601 agagatagtc gatcggctat tatcttatga tgattcctta aagcgaggct acgaagtcta
     3661 ccaggatttt ctttccgtta tcagaagaca agatgttcct gaattcgtcg cgctcctaaa
     3721 agaagactac aaggagttgc cagagcacta ccaaccagtg ttcacgacct tcaagaaata
     3781 ccaaacagaa atcaaacgag cgttgcgcgt tccctattcc aacggcccta tagaatgttt
     3841 gaataaccat atcaaagtac taaaacgaat tgcctatggc tatagaaact ttcaaaacta
     3901 ccgagaacga atctttttat atcgaggaaa atattttaag aaaactaaga atactaccca
     3961 actgactaaa gccagaacaa caacacggct agacaagata gctgtctagc cgtgtgagta
     4021 tctcgattat tctattgaat ttcttcacca acactcattg acgaagagcc aaaataagta
     4081 atctaaccga ctgttaacta aaccattgca ggtcccgtta aagatacttg tgcctgttgt
     4141 caccgcttct ttttcttgtc cacaagcgct taacacactt aataaagccc ctgctattat
     4201 taataataat atctttttct tattaaaaac ctcctcatct atttccagat tagtaaatgt
     4261 agtaatctgt gctttctttt ttctcaatac taataactaa cttatggggt aaacaaatac
     4321 tcgtttgacc gggttttgag atccatccag ttctaaccgc gatttgatca ggactattat
     4381 cttctttaac tcgaattctt ccatctttaa tctcaacaat attatattgt cccttcgcag
     4441 gatgataatt cacgagttta tgattgatct tatccaaatc gaagcgatcc atttccttgc
     4501 catcaattcg aacgatggca tatttgatag catcttcagt tgtttcattc tccttttcta
     4561 tagagaatac aaataaggga ataaaagagg taataatcaa aatgccaata attatgacat
     4621 cgcctatctt gacaccagct tttcttaaaa atttcattaa cgatatctgg ctaaacatat
     4681 tagacttttt ccatggaaat ggtgaaattt ttcggaaatt atctgcatta agagaatcag
     4741 ttaaacaacc ctcaagttgt tccttaatac attgttgatc catcttcata ccaataaaaa
     4801 ctagtttatt aatgcgttca ccaaacaacg gatgccaggc ttccttcaat tcgggatttt
     4861 tttgtataat catttgacac tcaattttag gtaaactagc tacccaataa tttaatgatt
     4921 caatactttt atagctaccc gatgtttcaa agatcgtcga aaaatcacta tgttgggcaa
     4981 accaaagaaa cccttttgct cttgtaatat tgccaggaaa atttttatcc gtaagatggg
     5041 caaatttttg tgcgtcaagg agtaaccgat ttcgatagat aaaacttgag ataccatatt
     5101 cttctgtttc aggaatatga ttttgatagc caagctctaa ctctttgaac cagcccactg
     5161 aataggaagt ctcatctata ttaaaaagat ttgtatttag aattttcgat aagtctactt
     5221 cacctttaat tgtcctaatt attttggcat tggactgtaa cttagcaatt agaccgttaa
     5281 ttttgtaaat cgtcttggtt gacactaagt cactattatt taaaagtaat atgttacaac
     5341 actcgaattg atcaattaac aagccacgaa tatcctgttc ttcttcaact acattacctt
     5401 cagcttttct ttcctgaatc ttttcacccg tttcgaaatt atcccaaaaa cgttttacat
     5461 ccactactat aataatggca ccaatctcta atcgttgggt caaatcaatg tctaaagggt
     5521 ttttagctaa tataattgct tgaataattg gaattggttt gctgattcct gaagcttcaa
     5581 taacaatttg attcaagtca gaaaattgca ctaattgatc tagttcaaca atcaaatctt
     5641 cgcgtaatgt acaacaaatg catccattcg gcatcgaaac aagtttttct ccagttcttt
     5701 taaaaccttt cttgtcgact aataccccat caacatttac ttcccctatg tcatttacaa
     5761 tgacagcaat ttcctttccg tgatcaccgt acagaatatg atttagaagt atcgtttttc
     5821 ctgaaccaag atagccagtt aagattgtaa taggtatttt tttcataggg aacctctttc
     5881 tataccttga atttacactt taagtgcaac acataaaaat gagtcataat cgatatccaa
     5941 ctagtataag tttgtcgaga acactcctag aaggaaaata attatgagcc agtatcgtca
     6001 tcttactata ctcgaacgag aaagaatctt tctgcttcac gaagaaggat tttctattag
     6061 tataattggc aacgacattc agcatagccc gtttactatt ttacatgaac tgagaagaaa
     6121 caagaaaaaa actattcacc ttccaaagcg gaaaaaaatt atgcttatcg aagaaaaaaa
     6181 tgcggacgtt atcacattct aaatgatccg tgagtttggt caattgttcg tcatttattt
     6241 gtcgattttc agtggtcgcc agaggaaatc tcgaatcgtt tgaagcatga acatatggac
     6301 ttttcaatta gttttatcac gatctaacgt gcaatttgca atgatctttt cgatacagaa
     6361 cccctctcac acggcaataa aggcctgatc cgttcattgc accatcgagg aaaaacaaga
     6421 catacaaaaa atcatgtcga gtctcgtgga aagatttgcc ttactcattc gatccatggc
     6481 cgtccaaaat ccgcagatga tagaagtgat tttggtcatt ggaaagccga tattgtagct
     6541 ggcaaaactg gtggtacttg tttagtgact ttgacagaca gaaaatcatg cttcctttta
     6601 gcaggaaaga aggtccccag aaagaaagcc gcttatgtga gcgagaaaat gattgaactt
     6661 ttaagcagta ttccaaatga ggcggtcaaa acgatcactc cagatagagg aaaagaattc
     6721 tccaatcatt tcgcagttac agaagcattg aataatatgc ccttttattt tccagatcct
     6781 catgcccttg gcaacaatga acaaattaaa atacgaatag actcattcga gaatacttgc
     6841 caaaatcgaa agagatagct acggtagata actcaacgat aaatcagatg attgaaaaac
     6901 tgaataacag acctagaaag tgtttagatt ggagaacacc ttatgaagtc ttctttgata
     6961 aagtgttgcg cttgatttga caattcaaga cataataaaa agcagatcaa atccaaataa
     7021 gggaaaaatg atctactctg gtattatcaa ttaattggcc aagctattat gccgttttgc
     7081 taaacgtcta cttcttccag tattgacctt gataaaacaa caatcaggat cccgttttaa
     7141 tactctatga actgtgtcaa tactaacatg taaagttgca gcaatatcag ctaatgtact
     7201 cccatttaat ctcatttgct ttgcaaatcg ataacgccga taagcatcaa tattcttgga
     7261 atccatagac aataatactt ttcttaccat gtatttcctc caaaaattga attttaatga
     7321 gccatcattt cttgagcaat ttcatgttta gacaatgaag ctggatagaa agtaggccaa
     7381 ttatgcaatt cattatagag tttttcttga ctttctccac caaagaaaat atggaaatgc
     7441 tctgccttac ttggtgcaat tccatgatca ctaaattgaa tatatttaaa acgaccagca
     7501 cctgcatcat cagtttcaaa attaaaacga acaccacggt ttcctttttc ataattcaaa
     7561 attttgtatc caacatattt gtatgtgtat tgatgatgtt caccgttgac tacaaaatca
     7621 atggtgttgt ctttaatgtt gatagtatca atatctgtct tatagccagt agtataataa
     7681 tctttgtact cggcagctgt catgtcttta ttgatttttg ctttgtaatc gaaaacttca
     7741 tccaaaattc catcttttaa caacggataa acagattgcc attcgcctgt ataatcactc
     7801 aattcgcgat ccttcacatc ggcatcttta aagtacccat tagcaactgt cttttcatcc
     7861 ttcgcttctt tttctggaac tacctcttca ccagcaacca tagttgtttt ttctaacgct
     7921 tttagattgt cttccattac tgaaacataa tcttcaccat tatccatttg ttcttttgta
     7981 agactttcaa gaggattcag tacttccaat tttatcccag cttcgttggc caaagttttt
     8041 gcaattttat cattagcatt cttttcaaag taaatataat tgatcttatt ttttttaaca
     8101 tactctttta attcagctaa tcgaccagaa gatggctctt cttcaggact tagtccagca
     8161 ataggaactt gtttcaatcc ataatccaaa gctaaatatc caaaggctgc gtgttgcgtc
     8221 acaaaacttt tttgtttcgc ttctttaaga ctagtggtat agtcagcatc caaccgtttc
     8281 agtttagtca aatacttttc agcatttgtc tcaaatactt ttgctttttt cggatacaat
     8341 ttaactaact gatccttgat atttgaaact tccttaattg ccattttggg tgaaacccac
     8401 gtatgaggat ctagttcatg atggtgatct tcttctccgt gatcatgatc ttcttcttca
     8461 ctacctggca ataaaatcat gtcttttgtt ccttctacta cattaggccc agctttcttc
     8521 caactttctt tagcttttgg tacccatgat tccatgtttt cgttatgata tacaaaaaca
     8581 tcagcatcat gagcttttgc catatcctta gctgagggct catagtcatg aggttctgat
     8641 cccgctggaa ccattaaatc cacgttcgct tcatcgccga cgatgttttt ggtgaaatca
     8701 tacattggat agaatgttgt tacaatttct aattttccat ctttatcatt cgatactttt
     8761 gcatcattag tgctggagca agctcccaat aatcctagag ctgctatccc aataagtcct
     8821 acactgattt tcttcattct ttttccttcc ttaattatgc taatttcttc attttatttc
     8881 gtttatgttc tttgataatt tttaatgccc tttttctagt tttaatattc gggcttttaa
     8941 gtcgtcgata tgcactagat atatccgttt tctccattag aaattacccc caatcactac
     9001 ttatcattat ttgctttccg ccagtaattt atcaaaactc tgtttgatcc tttcttcatc
     9061 caacattttt ccgattagaa taatagtggt ttggtctttt tgtcgagtgg tgtattgaaa
     9121 attaacctgt tcgtttacct cttgcatggc aactataaaa tcctgctctt gtaaagcaat
     9181 caatccttta aaacgataca ggctcccttg gttggttaaa atcagccagt caatccattg
     9241 gagtaaaaaa tcttttttta tgtcttgatc tgaagttaag agaattgatt taaactcatg
     9301 tacttgatgg tgttgatgat agtatttgcc attatagtga ttttctgatg aatcactttc
     9361 aaaaactaag ggatgattaa attttttcaa attataaaaa tccttttttt gaatcgtttc
     9421 actatgtgtg aacattcgaa tatcggataa agggttaata cttttgattt ctctctgtaa
     9481 tttttttagt gcagataaat tcaagttttg ttttctagac acaaaaatgc gatctgccat
     9541 gacaagttgc ttaagggctt gtggttctct ttcaataagt tcaaaactgt cactatcaat
     9601 aacagtcaat aaactatcga tatatactct tcctcttagt tgaggcgctg ttaaaagtgt
     9661 ttgaatgatt ggttggggat ctgctatacc tgtagtttca atgatgattt gtgaaattgg
     9721 ttgttgatgt tcttctattg tttccagtaa agaaatcaat attgctaata aatcactgcg
     9781 aagactgcaa cacatacatc cattatttag ttgtaacacc cgttcctcgc tatgaactaa
     9841 taatttgtga tcaatcccaa cttcaccaaa ctcattttca attataataa tttcttccct
     9901 ggggtagggt gagacttgca aggcttgatt gattagcgtt gtttttccag cccctaaaaa
     9961 cccagaaacg attgtaactg gtatgcccat tttgtcacct ttttaccact tagctatttc
    10021 acttctttaa aaattgcccg tctgcgcaat tttggcgaat acttttttaa ttctaaccgt
    10081 tcagggttat tccgtttatt tttgctggtg agatacagac gttctccagt ttcgacacat
    10141 tccaaaataa tattttgacg cataaatctt cctccttcaa tacttatcga tcttcaagat
    10201 atgcttgaat ttgttgtgca tcttcaaaag ttaactcgcc agattccaat tgtgaaacta
    10261 aattttcttt catatcaaca ggtatctccc aataaccatc gatacattga aataactcct
    10321 cgtcatactc ttcaaaaatt ggatagattc ttaaaaaatc atcaaatgat aagccttggt
    10381 cctcatagta atctttgact aatccatttt caattgcctg ttgggtcggt aaacccgttt
    10441 cagtaataat tcctctctct accatcgaac gataaaaagt gcatttatct agcgattgct
    10501 gggtcgtttc aagataatac tttaatcctt cttcaactaa aggtgggtaa ataatttcca
    10561 ttttgattcc ctcctaaaag ttatatatta aactattttg aagctccttt aattactttc
    10621 tttccattat agtacccttt taaagataca tgatggctac gtctataatc accattcgct
    10681 tcgtcaaatg aaatttctgg ttttactaca gtttgatgag ttcttcttaa ccgtttcttc
    10741 gccttagatg tttttcttgc tggtactgcc atgatatttc ctccttttac caacttgctt
    10801 tttttactcc aggaatcaac ccttgatggg caagttctct aaacttaata cgggacatac
    10861 cgaactttcg catataccct cttggacgac catccgtctg atcacgaagc ctcagacgat
    10921 tcggatttga atctcttggc aatttagcga gagcggtgcg atctcctgcg gcttttaatt
    10981 cctgacgttt atctgcatac ttttcaatca tcgccatttg tttctttgct ttagcaattt
    11041 tcgacttttt tgccatatac ctttatactc cttttatttt gatttagaca cctcaaatcg
    11101 taatcgttac gttttgacac tgatacttta ccaacaagag ttgctcttgt caacaataaa
    11161 taacatgaaa taaaactcat atgaatagat aactatttga aaacgaattt atcggtacat
    11221 agagataatc aaatcattta aaagaatatg cagtttaggc tctgaaaaat aagaattcac
    11281 ttttattagt ccaatcaaac acaaataccg ttttaagtag cttttcctct acttaaaacg
    11341 gcaatatgaa agaaactata actttttatt caatctttta tgtttaactg gtttatcgcc
    11401 aattttttaa aactttgatt attccttata ttataagaat agacattaag tgaactaatt
    11461 caatcatact gattctttcg tgtattcaaa attagatgct gtttaataaa attattcttt
    11521 ttgaaaaaga attataacta tatcccaaaa attgtaggtt aatttaaagc ctatttcatc
    11581 atcgtgattg agcttctttt tcatagacga atttctcaga tagtttagtt ttctttatga
    11641 gatttttgta tatttctgac cttcgataca actcattatg agtaccttga tcaactagtt
    11701 ttccttgatc catcactaca attttattta ccttttcaat agacttcaag cgatgcgata
    11761 taattagtac tgtcttatct tgtattaaac gatttaaact ttcctgaata cgtttttcat
    11821 tttccgcatc taaactggca gtaatttcat ctaaaattaa aattggcgca tttttcaaaa
    11881 aagcccgtgc tatggatagg cgttgtcgct ctcctccaga aagtgaactt ccgttttctc
    11941 cgaccaatgt atgataaccg tcaggtagtt tttcaataaa gtcttcgcag ttagctaaac
    12001 gagctgcttt tttcacttcc tcatctgacg cttgactatt tccaatacgt atattttcca
    12061 aaatacttgt attaaacaaa gttacctctt gaaaaacaat agcgattttg ctaaacaaag
    12121 aagctggaga tacacgttta atatcatacc catcaattaa aatacagcct tcatcataat
    12181 catacagtct agacactaat ttcaagatac tagttttccc ggaaccacta gcacctacta
    12241 acgcagtcac ttctccttgt ttagccgtaa aagagatatg atctaaaatt ggggtattgt
    12301 tatcatatga gaaagagaca tctcgcaact caatgtcaaa agatttcaga ggactatctg
    12361 atccctcttg gatactggtt tccttcatag ctctaattcg ctgtatttta ggagctaaat
    12421 aaaatatttc aagcactgct tctttcatag aatcgaagga atcctttatt tttattgcgg
    12481 ctagtaagta accaacgacg tagagtatag tcacttcacc cgttaacagt aagtgaacac
    12541 ctactagaat gactactgct aaactaacat atgagaaaat agaggataag gccatgactg
    12601 aaaaagtact taattctacc tttaaatgaa tcctttcact ctcttccatt tttttgaaaa
    12661 gtctgtcttg aactttttta gatagattaa agctattaat ctcttgctgc aattctatag
    12721 tttcttgaaa ttcttccgag ttttctctca aagtatcgta atatttagta ttggctttcg
    12781 tttgggattt ctttgataac aagattaaga caaaactaaa taacgttggc aaaataacag
    12841 ctaatcccat tttgacatta ccaaccaaaa gcatcactga aataaaaggg aaaaacagag
    12901 ccataccgcc ggctttaggt attgcatgac tcatcgcatg ctcaatacct tcaacgtcag
    12961 acatgatagt ttgagataaa tctgataaat tatgttttga aaaataggat aatggtaaat
    13021 ttgacaaatc gtctgcaatt tgcactctta aatgcgcact ttctttataa gtactattat
    13081 ataagttttc atactcccta tctaacaacc aatacatgaa aagcaaagta acaaacgata
    13141 cggcaaaata aagccaacgg ggctttgtat tttctaaaac taattcgtct atcagcatca
    13201 ttataatgaa tgctggtacc atattaatgc agtatacaaa aaaactagaa atagaagctt
    13261 tagttaaagc ttctgcgccc tgatcactta aagcaaattt gtttttataa aaacttttca
    13321 ttgtcaagcc tccaatcatt tgcattctca taattagtga ccaattgttt atacacttga
    13381 tgtttagcca ttaattcatt atgatttcca cgttctacta ttttcccttc tgacaagaca
    13441 agaatttcat ctacagattt aatgctggat aatcgatgag ctatcataat aactgttttt
    13501 tcttttatca gatgttgaaa agccttttgt agttcatact cattatctgg atcaatagat
    13561 gcactggctt catccataat aacaatcttt gcatctttta aaattgctct ggcaatagct
    13621 atacgttgtt tttctcctcc tgacagataa actcctttac taccaattaa ggtatgctct
    13681 ctttcgggaa atttttctaa aatcgattcg caaccggcta atcttagcgc gtcaaatact
    13741 ttacttgctg gcgcttgagg atttgctata gaaacgttat cgtaaatact ctgattgaat
    13801 agtttcgtat cttgaaagac aaaagcaatt gtgttaataa ttgtgtcttt tgaatagtga
    13861 tttaaaggct taccaccaat tttaatctgt cccttatcca cattgtagaa acctgaaatt
    13921 agtttagcta tcgtactctt tccgcttcct gattttccta ctaatgcata aattcttttt
    13981 tgttctaaaa ctaagttgaa attttctaaa acacactctt ctttgtatga aaagctgaca
    14041 ttttcaaatg caatgtcaca atttttaatc tgtgtctcgt tcccatattt tagttggtct
    14101 tgcttcattt ctaaataaag ggagtctagt gtttcgactg catatcttgc ttcaaacaag
    14161 tgcatactta catacattat tctcatgaaa gaaacaaaaa taattccact taaaaaaaac
    14221 aacatcaaca agtcaacagc taatatcttg ggagtggtaa gagaagttat aaaaaaggtt
    14281 ataggaacta tcaaaatgca aactatgcca aaaaatagcc attgaaaaag aacaaaaggt
    14341 gttttcccac tcaaagaata cttatatgca aacttagcat aatcgttaat tgctttattc
    14401 aaggctttaa atgatgttac tttagcacca aatatcttta taacttgaat tccgcggata
    14461 tattctaccg tttcagagct taacacatct aacgattctt gatatttttg aataaaattt
    14521 gtattctctg tcattttctt taacaagaat acaccaatta ctaacatggc gattagaacc
    14581 aatccaattt taaagttaat gaaaaagcct aaggcaactg ataaaacagg tgttactatg
    14641 gcttgagcac tatctggaat caagtgagca attgccatat gtgttttagc cgcgttgtca
    14701 tcaattgtct ttcgaatata tcccgaagaa tttaaatcaa aaaaacgaaa acttgcttct
    14761 gttaaaccgc taattccctt ttttctcaaa ttagtctcta agcgaaaccc aaggatatga
    14821 gaaaataagc cagaaaaaat ataaaataaa gctcctaaag ttaaccaagc aacagtttga
    14881 accgcataac tcttagctaa atattcatct cctacaataa ttagagactg aagaaatttg
    14941 taaatactgt aatatccata gactgttaat acgacagaaa aatcagaaaa taaagtggct
    15001 aaccatccgt agtatttcat tttagggaca taactaaata attttttgta tactttcatt
    15061 ttttcctccc ccgcattcaa tttcttctct tattcgttta caactgttaa tgctttccgt
    15121 aatagcgtaa attagagatg tacaaacaga taaaaggtaa actacgttct attttttgta
    15181 tttttttaag acttttcttc caatcaatac accaatcata gataaacttg ctacaactaa
    15241 cactgaaatg attccccata tacctaccgc atagtggatc attgcatcca ttgttgcagc
    15301 agattgtcct ttatctatcc aatcttgacg aaaacgatct gtaaagaacc atataggaat
    15361 ccactgtccg gcagcactgc ctaattgcat tagagcccaa gacgcaactt gaggaattgc
    15421 tcgatcatat ccaaatacag atagaataat atcagctaag atcgccatac taatcgaact
    15481 gataaaccaa ggtaagtacg ccccgcccat taacgtaaaa aataacaata aaacaattgt
    15541 gtaaatagta aaaattcctt ttctagggta gttatagcta atataaacaa atatgattcc
    15601 agataataat ccaaaaatcc cgggggatat gctgtgacca aacgccccac caatactact
    15661 aaccattatt gaaaaaaagt aaattactag ggaaataact gtagctaaac caataaaaat
    15721 ataatctttt gttttcatat atattctcct caattctatt tcgttatgtc attaaaaatc
    15781 tgttctatca aagttgaatc ttctactcta agttttatat ctttttttat tccaccattt
    15841 tttaaataaa taattctatt gcatgtttta taaagaaatt ccggatcatg agtagctata
    15901 actactgcac ccttttcttt taagtcttta ataaggtcag caatcctttc catattaata
    15961 taatccaacc cacttgtagg ttcatcaaat agaaataaat tagtttttga caatgaagct
    16021 atagaaacca ataatctttg tttttctcca ccggataaat caaacggtaa ttgatctttc
    16081 attttataaa gttccatttt ttttaaaatt ttttcttgct gatctttact aactatttca
    16141 ttccccaggg ctaactcgct cctcactgat tctgtgaaaa attggtaatc catttcttgc
    16201 attactaaaa acggcgatga caaatttttt ttattttcga ttatctttcc tttggtaggg
    16261 cgaataatct tcatgagtat tcttagtaag gttgttttcc ccacaccgtt tttccctacc
    16321 aaaccaataa catctccaac tttgacatca aaatttatgt cttttagaat attttcataa
    16381 gtaatttctt caacttttaa tacatctgca cttacctttt cgatataggg aacttcaatc
    16441 gaactattaa aaatgtcaaa tttccttaat gcgttattgt tttcagtttt taacaactga
    16501 atagttgtag tttttacagt tctattttta acaaatagaa cttgatcaat taattctttc
    16561 aaatagtaaa aacgatgttc agctataaca atagtaaatc ctttattttt taaatcacaa
    16621 agtaagtcag caagtttctt agtcgctttg aagtccaaat ttgaagacgg ttcatccaat
    16681 ataattaatt tagagtttag cgataaacta catccaatag aaattttctg ccgttcacca
    16741 cttgatagcg aaaaaatgtt tttatctaat atatttgaaa gatctaataa ttcagctaat
    16801 tcattgattc ttttatccat atgctctttt gtaaatccaa agttttccat cgaaaatact
    16861 aactcactcg ttgtatttgt tgtaaagaat tgtcctctag gatcttgact tacgtagcca
    16921 atattttttg atatactttc ttgtgttaag gattgtagcg agttattttc aaataaaatt
    16981 tccccaacca attttccgtc ataaagtctt ggaataagtc cattcattaa ctttaatagt
    17041 gtggatttcc cactcccaga agaaccagta atcaatgtaa gactgccttt ttttattgaa
    17101 aaattaaggt caacaagcgc ttgttcctta acatccttat atgaaaaaga aacattgtta
    17161 aattcaaaca attctttcac ctcaaatcaa aatacttaag aaaaaaatag taacggaaaa
    17221 caggatgata tagtctaata agctcatgtt tgttttatag taagaacttc ttttcacagg
    17281 agattctatc ccctttgtta ttgcattagc ggtcatttct tcagcaatca tagttgcacg
    17341 tataagaacg ggaactaaca gaaattccaa atattgcaga ggctgaaaaa aagacaagcg
    17401 aatgtttctc atttttaaag attctttaat cattcttatt tcagaacgat aagtcggaaa
    17461 gaatctgatc actactgtaa tacttaacat tatttttttc ggtaaatgta ttttttctaa
    17521 agaggataat aattcattgc tagtatagac actaaccaac aaccatgaga tcattacgac
    17581 cggcaacatt cgaaatacaa tatataagga tgtcgcaaaa aatatagtaa aaaactctat
    17641 cttgatagca tcaataattt tcattactaa aaacagaact gaataaatca agatgaaata
    17701 aatacatgtc tttattttac gaaacatcaa tactaaaact gtagcaataa tgaaacaccc
    17761 cacttgaaat atatttccct ttcctaaaaa aataatgacc ggaaaaaaaa tatttaaagt
    17821 aatcaaggtt aacggattga tttttgacac tctttcacct ccaaaaaata agatcgcact
    17881 gttatcttaa gctgataaaa atgcaccgtt attcagataa cagtgcgatc ttatcaaaaa
    17941 gcataactga gaacaattct caatgcaagc tttttttaat taactcagta attcaatcca
    18001 cccaggaaca gaaaattgat acaatcttct ggttaatagc atagtctttt cttttgaata
    18061 gctatgcttc aatatatcat agaatgtagc gtagaatgag taaatgtaga agtggatttc
    18121 ttcttcatta aagactaaat tttgattgat cattccgata gtctttaact tatctagaca
    18181 acagactgtc tttttcgtca caaatgatgt aattttttca acaatatctt gatatttggt
    18241 tccagctgat tggaataaaa tcaaatcgaa tatacgttta ttctcaaaaa tataattaat
    18301 aaatggatct aattcattga agttctctct ccaacttttc tctatatcta tattttctaa
    18361 gtttaagagg tatttggtaa actcttcatt atacatatta ataagcgcat taatatgcgg
    18421 ctgaataatt tcttcaaata acgcttcctt agaagtaaaa tgtttataaa aagcacccgt
    18481 agttacgcct gcggtcaggc acagttgcct tatcttagtt tgctgaaatc cttctttttc
    18541 aaaatggctt agtccacttt ctattaactt ttggtgagtt ataatataat ctctggtttc
    18601 tatgggtact tcctcctaat aagatgaatt aactttatta tcttacacag gacttgaagt
    18661 ttcaatcgtt aacgtttatt actgaactca ttccttagag ctaaactaat gagaaagagc
    18721 agaataactg atacaaaaag caatcctaca agaattaata gactcatcta aatcattcac
    18781 cttttctaaa ataatccgag aaagatttaa aaaaattata tccagctatt aggataagtc
    18841 ctatcataat cactccaata gccattttct tatcctccct aaaaataaag tcttttactt
    18901 aaaacctttt ttgtaatcgt caataaattt tttcccttta tcagttaatt gaaatcctat
    18961 atctaaatag tcctcatatc taagtttagc cagcatctca cttacagatg ctggactaac
    19021 acttagaact tttgctaaat cattattttt taatttcttt tttctttttg ataattcctg
    19081 aattgctagt aaataaatta gtatagtagt cgttttaatt tgtaccatac ctaccctcca
    19141 aattatttcg aaaggccttc agcaatttta tccaggttcc atttcatcat cgcatagtaa
    19201 ctatcaccat cttgtccttt ttctgcaatt gaatcagtaa aaatcgttga atagatagga
    19261 atattggtat cttttgatac tgttttcatt ggtctatcat ccacactgct ttctacgaat
    19321 aaggagggaa cttttgttgt gcgtaatttt tcaactaagt gttttatttg atctggtgtt
    19381 ccttcttctt cagtgttgat ttcccaaatg taagcagaag gcacattata cgctttcgag
    19441 aaatatttaa agcatccttc acttgtaaca atcatttttt tatcattcgg aattgaagca
    19501 aatttagatt tagcttcttt gtctagagaa tccaattttt caatatactt atctagattt
    19561 tctttataga attttttatt atcaggatct ttttccgcta actgtttttc aatattttta
    19621 gcgtaaataa taccgttttc taaatttaac caagcatgag gatcttcctt ccctttctca
    19681 ctctgaccct ctaagtaaat aacatctatg ccatcacttg ctgcaaaata gtctttgttt
    19741 tcctctttgt tcgcattttt aactaatttt gtaaaccaag catttcctcc agtttccaag
    19801 ttaacaccgt tataaaaaat caaatctgct tttgaagttt tttgaacatc ttcaggcaaa
    19861 ggttcatatt cgtggggatc tttcccaata ggtacgatac tgtgtaaatc aattttatct
    19921 tttgctatat tttcggtaat atctgctaaa atcgaattag taactactac ttttaatttt
    19981 tcgttcgaag ccactttatc tttgtcttta ctatttattg aacatgcccc gaatataaaa
    20041 agagcaatca aaatccccag acttcccagt actgctttcc attttctcat cataacgatc
    20101 tctccttctt tcttaaaaat ttttgttttg gtgagattag aaaactaatt acaaataaga
    20161 atgccgctgt taaaacaata cttgatcctg ctgctatgtt aaaactataa ccaataaaca
    20221 atccaagcaa tgatgaactt gctccgactg ttgcagaaat aaatatcata gttttcaagc
    20281 tatttgcata taaatatgct gtagctgctg gtgtaattaa cattgcaaca attaatatag
    20341 ttcccacact ttgcatagct gttactgcta ctaaagttaa tagaaccatc aatagataat
    20401 gataaaaact gacattcatc cctattgctt ttgccattaa tggatcaaaa gaagtgatta
    20461 ataattcttt aaaaaataga actactataa ccaacactaa aaccgaaacg ccaattgtaa
    20521 tccacttatc aatatcttgt acagctaaaa tatttccaaa taaaatatga aataaatccg
    20581 ttgagctatt tgcaactcct ataaggataa ctcctagtgc taaaaaagaa ctgaaagtaa
    20641 taccaattgc tgtatctcct tttattacac tattgctttt tataaaagta ataatgatag
    20701 aagctaatag accaaataca atcgcaccaa taaaaaaatt aatacctaaa atataagaaa
    20761 ttgctactcc tggcaaaaca gcatgagaaa tagcatcacc cataagagac attcctctta
    20821 aaataataaa acaacctact gttccagaaa caatccctat aactacagat gtaattagag
    20881 cattctgtaa aaagtgaaag tcatacagac cattaataaa attttgaagc atattattcc
    20941 ccctctccaa taaatatagt atctccatag gcttttttta aattttcttc attaaataca
    21001 gattctacac ttccgtgagc aattagattt cgattcaaaa gaataatatt atcaaaatac
    21061 ttctttacct tgcttaaatc atgatgcaca attagcactg tttttccctg atgtttcaat
    21121 ttttttaacg tatccataat tattcgttca ctaactaagt ctatccctac aaatggttca
    21181 tctaaaaata tgaaatccgc attttgagca agacatcttg ctaaaagtac acgttgaaat
    21241 tgtcctccag ataattctcc tatttgatga ttagaatatt ttcccatatc gaccttttcc
    21301 aaagcctttg aaactctttg ccattctgca tttttaattc tttgaaaaac tttcattccg
    21361 gcatatgttc ccatagatac acattctttt acttttattg gaaaagtaaa atcaatatca
    21421 gctttttgct ctacatatgc aatcttcacc agttttttat tgatatcttc attattaatg
    21481 gagacctctc cctgatgagg gataatattt aacattgctt taagcaatgt ggattttcca
    21541 gcaccatttg gaccaataat acctgttaaa gcaccttctt gtatttttaa agaaatctcg
    21601 ttcaatgcta aaaaatcgtt ataacaaaca ttaagctttt tcacttctaa cataactttc
    21661 tccttctaaa tgataatgat tatcacgatc atatggtata caaaaattat attttagtca
    21721 accctaaatt ttatagttta gatttttttc tgttgctgaa gattagaatg acaaaactat
    21781 ttgaaactac gcgtatagta agtagctttc aaaatatata aaaaaggagc gttctcaaat
    21841 gagaacatgc tcctaaaact actttattgg cgtatggaaa aattatactt gaagtggata
    21901 gcgggttgaa taagttgata agcatcaaaa catttataaa aattattcaa gactatgtct
    21961 gttccatata caaatatgaa aatcagtaaa ctccatttaa cttttttcgt agtgtgtctt
    22021 tttatacatg tttatcgtta ttaatagtga ataggaaaaa aactattttt gatcattgac
    22081 aattaaatac aatttttgaa taacgatccc tgctattcga gctagaaact caagtacgcc
    22141 atgacctgat tagcgacaaa tacttagaga tttctttttg ttctgggaaa acaaaatgcc
    22201 atgacaatag cagcaaataa tgatacttcc gtaaggctcg ccgtaaactg gggagaggtg
    22261 aaattcctat gtgcttaccc aaagcaattc aaaaatttca taactactat tttaggagat
    22321 gattttatag aatccagagt ctacctgaat aaaaaacaaa cctgtgcatt tctaggaatc
    22381 gataataata ctctagataa gtggattcgt atatataatt tcccagtaat aagagttggt
    22441 ggtgtagttc gctttgacgt agaagatatt aaagacttta tgaatacatt taaaataact
    22501 tgaaattttc ttctcgccgc atatactaaa attagtgaaa tatactgcct tacttttttt
    22561 aaggagtgag gattttgcct acaaagcttt caaatgggaa atataaaact aatctgagat
    22621 atccaaaaag gtttaaagaa ataacaggaa ttgcatcaga aaagtatcaa aaaacatttc
    22681 caaataggca attggcgatt aaagccgaaa atgatatgaa gaagaaaata gaaaaagttt
    22741 tgagagagga gaatgcaaac tcattagaat taaaaggaaa aataacgttt aaaaaatttt
    22801 acgaatctaa atggcttcct agatatgaat taggtcaaac aattagatca aacaggcctc
    22861 ctagtgatat aaccattagt aatacaaaag atatatttcg gttgcatatt ttacctatgt
    22921 ttggtgaata cgcaatgaat tatctaaata tcaatactga gataatatca gatgaattaa
    22981 ccaaaaaatc gaaagaatat gcaaatataa aaatcataaa aggatatgtt cgttccatgt
    23041 tcgatattgc agaaatacta aattatatcg aatttaatcg aactactaaa attattcaaa
    23101 gtatcactgc acctaaaaaa aatgctttag aagaaaaaag aatacaagaa ggtaagcaag
    23161 cactatcatc aaaagaactt actaattgga tagaagcagt aaatgatgat tttaataatc
    23221 atttacttac ttttcatgat tacacacttt ttatgattac cctgtatctt ggtgatagaa
    23281 aaagtgagac ttacgctttg caatggaaat atattgattt tgaaaaacaa acggtccgtc
    23341 ttaaacatac tttagataaa tatcaaagaa aaaagtttac aaaaggtcga aaagataccg
    23401 tcattcaagt accagaagtt gtaatgacat tgctaagtga atggaaatcg gtacaagctg
    23461 atcaattgtt gaaattaaaa attaagcaaa cgttagatca gtatctcttt acttatacta
    23521 aaccatctgg agaagtaaat tgtcctgttc atgccgatta cctaaactat cgaatcaatt
    23581 caattaaaag aaggcatcct gacttagttc atttatctcc acacaaactc cgtcatactt
    23641 atgcaactat agctagacaa ggtggagcag atatgaatca aatttcaaat gctttaacac
    23701 actcagatat ttctacaaca aagatatatg tgaacacacc agatatagtt gataaggctg
    23761 tttttgaagc ttttcagaga ggattgaata agtgtgattg atatgtgttc ttaaatgtgt
    23821 tcttaaaaac aaaagaagca ctttccaaat aattgaaaag tgccagaaac gttgatatat
    23881 aaaggatatt aacgttttga gaattgtgaa gctttacgtg ctttcttaag acctggtttt
    23941 ttacgttcga ccatacgtgc gtcacgagta agtaagccag cacgtttaag agctaaacgg
    24001 aagtcaggat caacttctag caatgcacga gcgataccat gacggatagc tcctgattgt
    24061 ccagcgtatc ctccgccgtt tacgttaaca aatacgtcat atgcgccttt tgtttcagta
    24121 acagcgaaag gttgattgat tacttcacgc aagtcagcat gtggaatgta ttcttcaaca
    24181 tcttttttat ttacagtaat tttgccagtt cctggtacta gacgtacgcg agcaactgcg
    24241 tttttacgac ggcctgtgcc gatatattga acttgtgcca atgaaattcc ctcctattag
    24301 attaagtttg tgatgtctaa aacttctggt tgttgtgctg catgtggatg ttctgctcca
    24361 ccgtatacgt tcaattttgt aaattgtttg cggcctaaag tgtttttagg aagcatacct
    24421 tttacagaag tttcgatcaa acgacgagaa tttttagcac gcaattcgcc agcagtgatt
    24481 gatttcaatc ctcctgggta gttgctgtga cggtaataaa ttttgtcagt cgctttttta
    24541 cctgttaatt tcactttgtc tgcattgatg acgatgacga aatcgccagt atccaaatga
    24601 ggtgtgaaag ttggtttatt tttaccacgt agtacagatg caacaactgt tgaaagacgt
    24661 cccaatggaa catcagttgc gtctactaca taccatttac gttctacttc gcctggtttg
    24721 gccatatatg ttgtacgcac gttattttcc tccaatttaa gttctgatgt ttgacataca
    24781 cttcgagttt ccggggctct ttgtggggca aacaatacca tttaacatat tacccgctaa
    24841 tctagtcaat gtcaacgttt ttctgcttga ttgaaaaatt tatatgaaac tttacttctt
    24901 ttctttcttt tatataaaag ggtcgtttcc tgtcaaaatg aaaaacaaaa agaggctgtg
    24961 acaaaagtct tgtcacaacc ccttattttg aataaacggt gttctcctgc caactcctcg
    25021 gtcacaagtc acaatatcca taaaacataa gaagctgttt tttaaaattg tttcttgtga
    25081 ctcggagctg aacggcaggc ttacaacctc ttggtaaacg gtgttcaatc agctgaccct
    25141 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttgacgtttg tttctctaat
    25201 actcaggtca aaacgctgat ttcacaacct ctttttcggt caagttcaac aacagttttt
    25261 acgcgtcgat ctctggcgct ttgcccaaat gagcttggat catccagata cgtttttctg
    25321 tggctgtttt gaattcgata aagatatctt gtgttggatc gtcgccttct tctccagaaa
    25381 cttcgattcc tttttggtaa agatctgcta gataacgata gcctgcaaca agtgtttcca
    25441 aacgttctgg aatagtacga tcccagcggc caatttcatc agggattttt gtgttatctg
    25501 caaattcacg caatgtagaa taaggtgaac cgtctaatgt gatcaagcgt tcggatactt
    25561 catctaactg agcgttcaaa tcatccatga actcatccat cattgggtgc aatgtaagga
    25621 aacctggtcc tctcatgtac caatgtgttt ggtgaacaac aacagacatt tggcttagat
    25681 ctgcaactaa ttgatttaat acttctttgg tttgttggaa tttcatcttt cttgcctcct
    25741 aacattttct tacacttaaa ataatagtag actttcaatg aaaagtacaa caaaatcatt
    25801 tacctgagaa cgattttcag ttcgcttttt tatccgtaaa gccaatcatt tttcagaatc
    25861 agctaattct tctcgcagtt gagcaaattg ctgataagtc tgtgctaaat gcttttgtgt
    25921 cgaaacaaat aatggataga ttttctgata ttttttatga tcagtttctt gtactccaac
    25981 ttgctctttc aattctatca attcctgtgc ttcactgata ctttggatct ttccgatgct
    26041 tctccagcct aaaatcacag ctcctaatgc ggatgcttct gtgacagtag ggaaaacaag
    26101 cgggtaaccc agtacatcag ccatcatctg acgaaaaatc ggagattgag caaacccgcc
    26161 tgtagcacgg atctctgtga gctgattttc ctggcaaact ccttttaaaa tccgataaag
    26221 gttgagacag atcccttcta gaatcgcctt catcatttct ttttctgtat gttgccgctg
    26281 taaaccgata aaactgccaa acgcatctgc gtcccaaagc ggtgctcgct caccaagtaa
    26341 atagggatga aaaatcagac cattggcacc cgctggcaca aaagcgatag ccgaaagcag
    26401 tgcatcatat ggattttctc ctttttcttt agcagattga acgacttcct gtaaaaatgt
    26461 atgccctgcc caatcaaaga tgccagcacc attgctagtc gctcctccca ctacccaatg
    26521 tttctgatcc agaacataac aaaacgtctc catttctgga tggaactgag gctgagtagt
    26581 aataaaacga agtgctccgc tcgttcctac ggtcaaagcg gcgatcgtat caccaaaagc
    26641 acctaaccct agattagaaa gcggcccgtc tgcccctccc aaaacaaatg atatatcatt
    26701 tggcaaacct agttctgctg ctgtttttga tggtagacct gttacttgat aggtggaagg
    26761 aaagacttgc ggcaattgct ctattcgaat gttcaagtag tcaagcactt cttctgccca
    26821 ttggaattca tggatatcaa aatatccagt tcctgaagct gttccgtagt cgctgatcag
    26881 ttcgccaaac aatctataaa agatatagtc tttgataccg acaaaataag cagttttttt
    26941 gaataattca ggttggctgt tttgcagcca cttgattttg ttcaatggtg tcattggatg
    27001 aatcggcgtc ccagtctgcc gataaaattc tttgccaagc acggtatatt tcagtttttc
    27061 tgcttcgtcc gctgctcggt tatctgccca agtgatcatt cgagataacg gtgttttctc
    27121 ttcatccaac aatatcaggc catgcatcgc agaggagaag gagacaaatt gaatgattgt
    27181 gtctgaaggc aactgtttaa ttacttcttt tataacggtg cagacacctt gaaagatcaa
    27241 ttcctgatct tgttctgcca tcccttgtgt ttcttggatc aaagggtagc gaaaataagc
    27301 ggatgctgct tcttgggctt catctgtgaa agcaactgct ttggtttgtg tggttccgat
    27361 atctaatccg attgaaacgt tcattttttc acctcaaatt ttatgtatgt acaaaaattt
    27421 agtttaagct tgcgtatctt ggttttgaaa agggggagat ggcgtgttac tttattttat
    27481 cattggttgc tgtatcggat catttttatg tttaaccgcc cagcggattc cgttaggtca
    27541 ctctattatt tatcctagat ctcattgtgt caaatgctgt cgttcgcttt cttggtatga
    27601 attgattccg attctctcga tcatcgtcca acgatttcgc tgccgctatt gcaggtgtcg
    27661 gttgcccttc tactatttgt tggcagaagc cttatgtggt ggtctttttg cctggttctt
    27721 tactttttct tccgcaagaa atttttcgac gttcatatgg atgctttcgg ctttgctatt
    27781 ttcgttgatg gatttatttt acttcatggt ccattctcac acgctattct gttcttgggc
    27841 aattttatgg attttttggt tgcaggccgg cgtcttccaa tggcaaagtg tgctgttaac
    27901 gtttatcgta ggcggtgtgt gccttcgcta tggtcaatcc tatctcggag ctggcgatac
    27961 tctgttgatg ctttcttgga gtggtggctt gtctctagaa gagttgcttc agatcttgtt
    28021 tcttgctagt ctgtttggaa tatccgtttt ttctgtttac tttatctgtc ataaaaaaaa
    28081 gttggaaaag ctgcctttca ttcctttttt gagcagtgcg ttgctgattg tccttcatct
    28141 taggtattga aaaaaggttg tgacaaacga cttgtcacaa cctctgatat atagtgttct
    28201 cttaccaaat ccttgtgact tggagctagg cgacaggttc acaacctctc cactaaatgg
    28261 tgttcaatca gctgaccctc agtattagct caaaatgctg gttttacaac ctctgatata
    28321 cggtgttcca taagtagctt tttcggcttc ttatttcttg acgccccaat gtcgacgaag
    28381 gaaacctgca cgtccagaac cttctcgata aagattgtaa tggagcttgt ttttcttgta
    28441 ataatcctga tggtaatctt ctgcaggata aaattcgctt cttggttcga tttttgtcac
    28501 gattggctta tcgaatcgcc cgctgtcttg caatgcttgt tttgaacgct ctgcaatatt
    28561 tcgttcttct tcatcattat agtagatcac tggacgataa gaatcaccgc gatcagcgaa
    28621 ctgtcctaat gcgtcagtcg gatcggtttg ctgccaatag atttccacca actgatcata
    28681 agaaataact tctggatcat attcgatctc tactgcttct gtatgccctg ttgtgcctgt
    28741 tgttacttgt tcataagttg gatttggtac atgcccgcca gtataaccgg atgtcacaga
    28801 aatgatccct ggctgctctt caaatggttt gaccatacac caaaagcatc cgcctgcgaa
    28861 aactgctttt tttgtcatat aaaatccccc ttttttctca tcataccttg atttccaaaa
    28921 ggaggataac gttttgcttg tgacagaaaa aacggaaact attatatacg tgatacggct
    28981 tctgataaat gccaaaacga acgtacttga tcaaaaacgg ttaaatcagg aatcacatat
    29041 tcagcagaag gaagatttat gttttcacct attcccaata catgcatgtt accagccaaa
    29101 gctgcttgac aaccagcttc tgaatcttca atgaccaagc atgcatttgg cggtacattc
    29161 aattgctgtg ctcctttgag aaaaacttct ggatcaggtt ttgcttttga tacttgcgtg
    29221 ccgtcaataa ggacatcaaa ataacttgtc aaattcgttt tttctaaaat gaggcgtgca
    29281 tttttgcttg ctgatcccaa tccgatcttg atgtttgttt ttttcaagta ctcaagaaca
    29341 gctattgcac caggcaaaac ggatgtttca tccatttttt gaatcgcttg aagatataga
    29401 ttgttttttt gctcagcaaa ggctgatttc tctttttctg agaatttctg ttccattttt
    29461 ccaaatgaca gcaatcgctc tagtgactcg gttctggata ttcctttcag ttgctcgttt
    29521 tctttctcag tgaatggaat ggacagctgg ttagctaaaa ccagccacgc ttcgtaatga
    29581 taacgagctg tgtctacaag aacgccatct aaatcgaata gtgctgcttt gattttcatc
    29641 gattacctcc ttgaaaatga acgacttgaa gtaaagatgc gatgttttta gctgtgcgat
    29701 gaagattatc agtggcttgc tgtaaagctt cttgtaaagg cacagctgca ggaaggatcg
    29761 gaaaaacggc cgaaatgcca acatctgctg ctttttcgct tcctttacca acacttccgc
    29821 aaatagctat cacaggaacg ccctctggta ctcttctagc aatcccaact ggcgcttttc
    29881 cttttagact ttgtccatct agacgtcctt cgcctacgat tacgaggtct gcttgctgta
    29941 cccgtttatc gaactccagt aaatccaata cgtagtcgat gccagagact attttccctg
    30001 aagcaaatgc taacagtcct gcacccattc caccaccagc actactgccc gatgcctcga
    30061 ttacttgagg ggcaaatctc atataaaaat catgcatggc ttggtcagcc actgctaatt
    30121 cattttcttt caagcctttt tgtggtccga aaacaaaaga agcgccttct tttccgcata
    30181 aaagattagt aacatcagta atgacagtga ttttggcttt aatcagctca ataggcacgt
    30241 tcgttttatc aactgtagca attttaccta gattttctcc cagtgcttct actttttgat
    30301 tatcttgatc gtaaaaagca taacctagac cttctgccat gccgatgccg ccatcgttgg
    30361 tactacttcc gccaacgccg atgatgatgt gtcgaacacc ttgttgcaac aattgtcgta
    30421 tcagttctcc tactcctcgc gtggataacc taagtggctg ttgttggttt agtgggacat
    30481 ctttcaatcc gacgatttct gccatttcaa aaatcgcagt ttgaccgtct gaagcgtact
    30541 ggatttcttt gtttttgcca aatgcattag taacgactgc tgtttgccgc ttcaacctta
    30601 aactgtctgc taatgatgaa accgttcctt ctcctccatc gcctataggt agcagatcat
    30661 attcagcctg aacaaaaact tcttgaaaac ctgattgaat ggcttgtgct gcctctaagg
    30721 ctgtcagact ttctttgaaa gaatctggcg caatcagaat acgcattatt ttcccctccg
    30781 ttccaagatc agttcttttt ccagctggta ttggtctcca ttgacaaaaa taggtaatgt
    30841 ttctttcgtc tcttttttta ttactatttg tttttttgtc aaaacaaata gcaacctgtg
    30901 atttttccaa ataaaaggaa aagaaatttt ttcccatgct gaaggaagtc ttggagaaat
    30961 agaaagagtt ccattcgtta ctgtaatacc tgaaaaacca aatataactg ctagccatag
    31021 tgctcctaat gaagcagcat gaattccgtc atctgatgaa tgcggatctg gtcctaaatc
    31081 aatcaggcac gcttcttgga ataaatgata cgcccattcc atttcttgga tacggcaagc
    31141 ctctatggcg tgaatcgctt tactcaacga tgagtcgtgg attgttttgt tttcatagta
    31201 atgcaaattc ttagaaacga ttggttgaga aaaatactca ggtaataagt ataacagcat
    31261 gacaagatct gcttgcttgc tgacttggag ttcatttact tcgctacggg cataatcaag
    31321 taaaatagac tggctgccag gacgttcttt gtaagtggtc aaatcaataa ctggcttact
    31381 gagatacgtg tcatcttgcg gaatcagctg ttctttgtta ggcactggca aatataactt
    31441 atctaaaaaa ttttgacatt ctttcaaaaa aagcggatcg ccagcttgat atttaacagc
    31501 taaggccaca ttataatgcg ccagatagtt cgtatatgca ttattgtcga tatattctgt
    31561 gtattcatct ggaccaatga ctctgtgtat ctctaaatga tcatcgactt ttacagctct
    31621 gctcagccaa aaagctgctg tttcatgaat gagcgttttt ccctttgttt ctaaaaacga
    31681 ttgatcctct gttgcttgga catactcttg aacggcataa gcaaggtctg cactgatatg
    31741 atgttctgcg gcagctgaag caacttcttg tcttgttccg gttttgatat tcaatgcagc
    31801 aaatttgggt gtctcttcct gaccagtgtg tgcgctttcc catgggaaaa gtgcaccttg
    31861 atagtgataa tctcttgctt tttgccgtgc gccttctaat cgatcataac ggtacagcag
    31921 caaattcttt gctacttcag gaaactgata taaaaagaaa ggcaggataa aaatttccgt
    31981 atcccagaaa acatgccctt tataaccttc gccagttagt cccttcgccc ctacactaac
    32041 acttggatca ttgcggggag tcataatctg taaatggtaa gcagcgaagt ccatcgctaa
    32101 ctgatcgaaa gaagaatcgc cttggatcgt tatccgatgc tgatgccaaa aatctgtcca
    32161 ataagacatc gactgctcta aaatttctgt ataactaacg cttttctggg cttgggcaat
    32221 acttttctta aacgggtctg tttgctgaag agaggtagag agcacgatga tcttctccag
    32281 cgtaaaggac gtattttttc tgatcttttc tgaaaaggaa gcggtgatcc ggcgattttt
    32341 tgcttggaat acacctgctt tattgaattt agctgcaatc ccaatatcaa ttttactttc
    32401 tgttgtctgg taggatgcac tgatcaaatc gtcaccaaat actcgcagtt ctttttcaac
    32461 caactgctgt gtaccaaaat tggtttgctg tccatcgata cccgttttca catctacttg
    32521 gcagtcttcg gtcaacggct tgatgaccac tttcagggct gcctgatgga gattattttg
    32581 atcagcaaca cgacaagtaa tgacttccac tttttttcct tgagcagttt caatgagcgc
    32641 atagcgttta agctctccca tttctaaatc tagtgcccgc tcgtatgcaa gaactttcat
    32701 cgtctcaaga gaaaaatgtt caccgtcgat ttttatttcc catctgatga catctgggag
    32761 attcactaac tcggctgatt ctgctcctaa aggtcggtta tatacaccag ctgcaaacat
    32821 tccccttact tgattccgat agtcttcctc ctggcttcct ctgataccaa aaaatccatt
    32881 tccaatggtc atctgactcg catacttatt gatatactct aaatcaaact gtttttcttc
    32941 tactttcata aggtaataac ttctcctgtt tctgccgaac gatataaatt ttccaccaga
    33001 ttctggatga catatccttg ccagccatct gcaatcatct gagtctggtc accgagcgcc
    33061 cgattcacaa aatgagccat acttagttca tgtgggtcat taactggcgt ggtcttttgt
    33121 aaggaaacca gctttccatc tacatcttcg aatagttcgc ctggatacag attagcacct
    33181 gcctgatcgc cacaaaaagc cacattcagt ttgtcttctc tgatattcaa agcaaacgaa
    33241 gtattcagtt ggatgatctt gccgttttct aattccagtg tgccaaaaat tgcatcttct
    33301 actgtgaatt tgcttggatc ccatttcccg aatttccctg aatttttttt cgtaccaatt
    33361 ttttggaagc tgtacgcccg aacgcttttt actttaggaa atccagtaat atacatcgct
    33421 gtatcaagca tgtgaatgcc ataatcgatc aaaggcccgc ctccttgaag ttctttgtcg
    33481 ataaacgttc cccagcctgg aacaccagac cgacgaagcg cattcgcttc tacgtaataa
    33541 atatccccga gaacatcaag atgattcttg atcattgttg cttcgtcaga aaaacgatgc
    33601 tggaatccat aagccaaaat ctgcccgttt ttatcggctg tctctgccat ctttcttgct
    33661 tgatcagctg tcatagctgg tggtttctcg cacatcactg aagcattagc ttcgagggca
    33721 gccaatacat gttcgaagtg aaagcgattg ggtgtacaga cactcacgat atcgggagaa
    33781 atctcattca gcatttgtgt aactgatgta tacgcatgag aaaatcctgt acgtcggcaa
    33841 aagtcttctg ctcgctggct gactggatca accacagcgg ccaattctaa gacatctgat
    33901 cttttttgat aataagcagc atgtactttt tctgctactt gtccagcgcc tatgattgct
    33961 actttcttca tttatttctc cctcctttgc ttatttactt attgttattc tttctctatt
    34021 ctttctctaa atcatttaaa tgacgcgctg tttccagaca gtttttcaag tattgcaatg
    34081 attcctgata aattttcact tcattttctc ctcgcaaacg acattcatat accatataac
    34141 cttcatactc attttgaagt agcgtttgaa aatggcgagt aaaatcaatt gcgccagatc
    34201 ctggttggta gcgatgatta tctgctaaat ggatatgacc cacatactct ttttgcgtag
    34261 tcaatgcttt tgaaatatca tcttcttcaa tattcatatg ataaaaatca gcgatgatct
    34321 gcacatgttt caattgatta gagtcaatgt aatgacgcgc atccgctaac aaattgatca
    34381 tatggtcttg gtatcggttc aaaggctcca aataaataac cgtacctgtt tcttcggcta
    34441 ctttatctaa ataacgaagt gattcgctga ctgctttata gtctccttct ttgcttcggg
    34501 gtgaaaccat cggcggtaat cgataagtga acattcccca agctgctggg ataacgattc
    34561 ctttgcctcc aacctcgctt agtgcacgca aaatctcagc aatttgacgt acaccattaa
    34621 gacgccgttc ttcgataaag tcaccgatcc acccatcgta gccgttacaa gctgtcacta
    34681 ctgggatccc tgtttctttg attgcctgtt tgactgtgtc gatattttct attaacaact
    34741 taccgtcgat ttcgtattct tcaaatccac agtctttgat aaatctaaat ttttctaaaa
    34801 tgtctcttgg gaaaaatgct tgatcttgcg taccgaattt cattgttctc ctcctcggac
    34861 ttgaacgccc attttgatac tttcttctgg gtgctggtct acataacgca tgtaagcttc
    34921 tgcgctttct gcaaatggca caactggatc aatgatttct tcacaatcca agtaaccgtt
    34981 catcaataat tcccaacatg tgtcctcgat tcgtttacgg ttccatcttg ggtaatctgg
    35041 gtttggttca ctagatgctc gagcaaagac gatttttgca ttattgaaat gtgcttcgcg
    35101 accaagatta aacccagctg gaaaaggttt agcaaaggca acataagaaa tgatcccgcc
    35161 atagccgatc cctcttaaag aagcttgtaa tgcggcagca ctgccactcg tttcaataac
    35221 tgaatctact ccacgtttat ctgtcaattc ctttagacga aaaccgacat ctgctttcat
    35281 aggatctagc gtgtaatcgg caccgtattt ttctgctaat tctctacgct gcgctatggg
    35341 atcgatccca acgatggtag tagcacctgc ttttttagct aattgaatcg caatttgccc
    35401 gatagcgcct aaaccgaaga ttgctacagc atcacctgct cgaacatgtg cttcccggat
    35461 accacctaaa gcgaattgag caggatcgta acatactgca tttttccatt gatccaaccg
    35521 atcaagttta cgtagtttat aattatcaac accgtttgta atcagcgttt cacgaatggg
    35581 tccataagtg cagactaact ctcctttttg atactctgtc accaaactgc ccgtttcttc
    35641 gatcgtaccg acaatcatat ttcctaattg aaattcgcca aataccacac cgcgttggct
    35701 tccttcttct cttggcaaga ataggcgcca ttcttctgaa aattcttcat cgataaatgg
    35761 acttaatcct ctaaagtcga caatttctgt tcctggtttt ggagtagcga aaattactcg
    35821 gatacgtact tcgttctttt cgatctcacg gtcttcgtaa tctttgaatc cggctattct
    35881 tggttctaat gcaactaatt ttttcatctt ttctttcctc tttcttttct ttttatcctt
    35941 ttacgccgcc ttcgactaaa tcacctttaa taaatcgttc agataacgca tacataatga
    36001 tgactggtaa agcggtcacc aatgaagcgg ccatcattcg tccccaaatg tagtctggtg
    36061 tactgaataa tgtgttcaaa ccgattggta aagtaaattt ttcggaggtc gacaggaaaa
    36121 tcgaagcaaa taaataatca ttccacgaaa ccataaagca ataaacgaag acagaaatga
    36181 ttccagaaat agccaatggt ataatgatcc gaataatgat ctggatccgg ctaagaccat
    36241 cgatcattgc tgcttcttca atatcagtcg gaatcgtgtc aaaataactt tttagcatga
    36301 atatcgcagt aggaagtgtt tgaacgacca tcgtgataat cagtgctgta ttggtatcat
    36361 acaaacctag accggaaatg attttaaata atggaacaac gatcaaaata ccggaaaaca
    36421 tataaacggt gtaaaagcta gcattgattt tcgagcgagc tttgaagcgt agttttgaca
    36481 aagcgtatgc cccgctgatc ccaatcacta ctgcagttac ggaggctatc aaggagatca
    36541 ctaaactatt tttgaaatac atgatgaatg gaaaaatctc agcattgaaa atatcctgat
    36601 aatgttcaaa agtccattct ttcggaaaaa tagtttgtgt cgttgcaatt gcttcttgtg
    36661 aatccttgaa tgatgtcatc agcatgatca aaaatggaaa caaattgaca gctaatagca
    36721 acaaaatcgt cgcgtaaaat aagattttcc tgctcttttt atttttcatt tcaagtccac
    36781 cttctttcgt gagagcaaga cgaccgctgc aataatgatg aacaatagaa tcgatatagc
    36841 tgctgctttt ccaagatcat tgaacgcaaa ggctgtctga tacaaataaa cgcctaagat
    36901 attgacttta ttcgtcagta gatagacatc tgtaaacata tagaacatcc agatagatcg
    36961 taaaacaatc acagttgcta gtactggttt gattgccggc agtgtcacga tcttgaactt
    37021 ctgccaagca tttgcaccgt ccatttcagc tgcttcataa agcgttttgt cgactgtttg
    37081 caaaatagcc aaaaatgaaa taaacgcata cggatagtat ctccagatag caaacaaaac
    37141 gaccataaag aagctagcaa ctggctggtc gaaccacagc ggtgcttcgt tgaaaagctg
    37201 caacctatct actaacagat cattgacgat tccataacta ttattgaaca tatatttcca
    37261 agcaaaaatc aaagaaatag atggcgtaac ataacttaat aaaatcagtg aacgcaccgt
    37321 tttcctaaat ctgaacttgc ggttaagcaa aatagctacg gctaatccta aagctgtact
    37381 gcctgctaca actaagaatg tgtaagcaac tgttaaacct aaagaacgat aaaattcact
    37441 atcacttaaa atttcaagat aattgcttaa tccgataaaa acggcgtctg agttaggatt
    37501 cagcggcata tcgaaaaaac tgatctgaat attggaaagc attggaatca gcactaaaac
    37561 agctaataaa agcatgcttg gtgctaaaag tcccatggct aattttaagt cagaatgttt
    37621 ccttggacga ttcattgaaa cctccccctg ataatctgcc aatagctatc tacttttttc
    37681 gaacaccatt ggcagaactt cttgttattt cgtatttttt tgtgcgtcag ctaaagcttg
    37741 atcgacatct tcgtttccga cagttacttg gttcactgct tttccgatca cacctgagct
    37801 tgtgatatct cccattttcg tgaaattctt ttccccgact agtccaaaga cttgtacttc
    37861 atcaaaagca ctagcaatct cagatggcag ctcgccaaaa gacttgatga cttcattttc
    37921 tttgtaacca tccagttcga ctacttgttt attcactggt tgagcaccac caggagacat
    37981 caagacccac ttttccatgt ttttcggttg agataagaaa gctgtgaatg cttcagcagc
    38041 ctctttttgt ttctcgtcta gaccagaaga aatcgtcaat ccagatactg tgccatagac
    38101 agcttgatct ttttgtgttg ggatagcaaa accgatattt tctgagttcc ccgcttcata
    38161 aacagaaggc aaaatgtaag ttgaatagat tgccattggt gctgttccat tcatgaaagc
    38221 atctttgatt tctgtcacat cattagagcc tggcatcgtg tattgggata agttttgata
    38281 aaacgacaat gcttctctca tcttttccgt atcgatcgtt acctcgcctt catcatccaa
    38341 aacatttgct ccatttgaca aagcaaattg agagaacgct tgctcactca ttgttccttc
    38401 agcagtaggc atagcaattc catattgttt attctcttta tctgtgaaat gttgagcaat
    38461 ttttaaaata tcatcccaat tttctggttc tgaaaaacca gcttctgata atttttcttt
    38521 gtcataccaa ataccttgaa cccagccgct aattggtgca gcaatatagc tttttccatc
    38581 ttctgaacga acaaggtttt tggctccgtc ataataatta tcttctccag cttcctcgat
    38641 aacgttttgg actgccgtct gatcaatcag ttcatcttta tccatcactt tagcaaaatc
    38701 ctgactgact tccattactt ctggtaattt accggaacga gctaacgtaa cgatttttgt
    38761 attgaacgct gattcttcta ccggcacttg cttgattttg atgtctggat tttctttttc
    38821 aaaatcagca accagttcat tgatcacact taatcgttcc tgttcgacag aagagtgcat
    38881 gaattgaatc gttgtctgtt gtgattcgtt agagctttga ctttcaccac aagcagtaag
    38941 aagaaatcca gtagctagca gacaggtagt aacaataatt tttttcattt ttttccacct
    39001 cttattttat tattttcagc cacatatatt catacggctg gaatatcaac tttcgttctt
    39061 gactgcaatg gataatttgt ccagaaaaca ggtctaggta atctcctttt ggtaaaagat
    39121 aacctgctga ttgattggaa aaattatgga taactaagac tttctcttcc ttcgcttcgc
    39181 gaataaaact gataaaagaa tctgctgagt ccagtaagta aatcaaacta ttcggatgga
    39241 aggctttttc tttttttcga atagatagca tctgggtcaa ttcaccatat actgctgttc
    39301 ttaatggatc tgtctgcaac tctttctcaa tatctgctaa caaaaatttt tgccgattga
    39361 tttttcgatt ctctcctgtt ttttctacgc ctttgtaatc atttcgactt cccagcacac
    39421 tttgaatata aattgccggc acgcctggta acgttaccaa aaatgaatga gcagctaaaa
    39481 agcgtttgct tctccattcc gtcgtatctg ttggagaact taacgcatct agatacgtag
    39541 cgtttatctc atatggactg gtcgttccat ctgggttttt cttgtagttt actcgggcac
    39601 cctctttctt cagctgttcc actaattcaa ggatcgtttt ttccggcaga atacctcgta
    39661 ccggattcaa tccgataccg tcatgggagg ctaaaaaatt aaaaaaagtt gtttttttcg
    39721 atgcgaaatc gatggttttt aaccattctt tcaacttact tgtattaccc gaacgaatcg
    39781 cttgaagggt caaaggtggt agcgaaaact gatagaccat ctgtgcttca ttctcgccat
    39841 tcccaaaata actgatatta tctttgtgtg gcacatttgt ctcagtgatc aataccgttc
    39901 ctggagctgc ttcatcagcg attgcacgga ataattggat gattttatgc gtttctggca
    39961 ggtgtataca agaagttcct agttctttcc ataaaaatcc cacagcgtcc aagcgaataa
    40021 atgaagcgcc tttttctaag taaaacaaaa gaatatcgat cattttcaat aaaacttctg
    40081 gatttttaaa attcaagtct acttgatctt cgctaaaagt cgtccatacg tgtttttctt
    40141 tcccgttttt gtcaatgaac gttgtaagta acgggctggt ccttggtcta gtcacgctgc
    40201 ttgtatctgt atccagtggc aaatcaataa aaaaatcttt gtacgtatca ttcaagttta
    40261 aatattcctg aaaccaagta ctttcggcag acatatgatt gcagacaaag tcgaacatta
    40321 accgtgtttc gcttctcatt tcttctatat cttcccatgt gcccaaacgg tcgttgattg
    40381 cctgataatt tacaacggag aaaccatcat cagatgtata tgggaaaaat ggcaagaaat
    40441 gtacaactct aaatgtatct gccaaatact tttgataaaa tttcttaaat gtacgcaaag
    40501 ttggttgctg ctcttcaaaa aattgatccc cataagtaat caagaaaata tcttcttcgt
    40561 cccaatgcag tttgcctgcc tggcctttct tctgctgata aacactgact ttttgttcaa
    40621 tcatagaggc ggttttctca gacaaatctg agtcgcgata aatcgcttgt aaaagttttg
    40681 tatacatcgg attccccttt cttttttggg agcgttccca acgatttgat catattatgg
    40741 aaaacgctta ctgtcaatag cattttttta aataattttg atatacacaa aaatacaaat
    40801 aagaaagctt atgtatcaat aattaatagc ttcttaaaaa aatatggtct ctcatgatca
    40861 tgcaagctat tcctaaattt tcaaaatcat agacaaaaaa gaatgtctat tgtactatgg
    40921 aattattcta aaacgctccc aaaaaggagg tgcatataaa attgaaacct actatttatg
    40981 acattgcgaa aaaagctaat gtctcaaaat caactgtctc cagagtatta aataaccagc
    41041 caaatatctc tgataaagca aaagcaagtg tacttcaagc aatcaaagaa ttgaattatg
    41101 aaccgagcaa aattgcaaga ggactgtcag gaaatggttt tgacgcgatt ctagcattat
    41161 ctcatcgtac ttctcatacg acctatggca atcctttttt ttcagatgtt attcaatcca
    41221 tttctgccgt ttctgaacaa aataacttcg acttgattct acaaacggca aaaacaccag
    41281 aagaagagct agaaaaatgc gcgaaaaaga tccaagaaaa aatgatccga ggaattatta
    41341 ttttaagctc tacgatggat gaaacacttc tttttgaatt ggatcaatac aatattccta
    41401 ttgtggtaat cggaaaagtc ggaaacgact acacgaacat ctactcagtg gacacggata
    41461 atttccagga tagttacgat ttggtggaaa cactgatcaa gaatggacac cgtcatatcg
    41521 gctgtctcca tgctccgaca gaagtttatg tatccaatga tcgtctcaat ggttaccgtc
    41581 aatgcttatt tgatcaccac ctagatatcc gtaatgaatg gattatagac ggcggctttc
    41641 gcttagaaga tagcatggca gcaatgaatg atttaatgaa gctacgagaa agaccaactg
    41701 cgattttttc taccgatgca ttaaaatcat tgagtattta caaagtggca gaacaatctg
    41761 gaaagcagat acctgatgat ctttcgatcg caggattcag tgatccctta ttgtcctccc
    41821 tattttcgcc acagttgact cggatagaca ttccgacaaa tcagttagga atcaaagcca
    41881 cagaactttt attccaacta atccaccacc aataccctga agaaaaaaga atcattcttt
    41941 caaccgagat tactctcaca gattcgatcc aacaacaaga aatgtagaac agaattataa
    42001 aagaacagaa acactgagga taagtcagtt actctgttct tttttcaatc actcatccct
    42061 cgttaccccc tcccggtatt ttagcgaatt tttcttattt tccatctgtt ttagatagct
    42121 gtggataact ataatgtttg tgttaaacta ttttttccac agggaagaaa aaactatttt
    42181 taaccacgtt gtgtataagt ttttatagtt cgttttttta aacacattta cccttatttc
    42241 aatccatgtt atttggggat acttatctct aaaacataaa tagaataaca gacatgtcta
    42301 ctggttttgt tttattcgag gaattattca ataatagcta gcaaaatatt aaaaataacc
    42361 gctctatctt cccatcaatt tattttgcat tcaaaaaatg atctatcttt acttttgttg
    42421 attgacttct cttggaagat gatcgttccg ataccttaat tggatacgaa ccgatgttgt
    42481 taagatcctt tcccactttt cttctagtta gacaaattat tttagacaaa ccaaaaaaga
    42541 ggttgtgaca ataatttgtc acaacctctt ttttaaaata tctattttgt ttgattgttc
    42601 attgcgtctt ctgcagccat ttgcgcttca atatctgaaa tactgtagac attttcgctt
    42661 gctacaccga cttcttttgg ttccatgtca cgataacgtt gcataccagt accagctggg
    42721 atgatcttac ctataataac attttctttc aaaccaagaa gaggatcttt cttaccgcgg
    42781 atcgcagcat ccgtcaagac acgagttgtt tcttggaatg atgcagcaga taagaaacta
    42841 tttgtttcta atgatgcttt tgtgatacct agtaagacag gtcgagaagt tgcaggaacg
    42901 cctcctgaga ctagcgtatt gtagttttga tctttaaagt ctgcgatgtc taataatgta
    42961 cctggtaaga tatctgtatc acctggatcc attacacgaa ctttacgcag catttgacga
    43021 accattactt cgatatgctt gtcgccgatt tctacccctt gcatacggta aacacgttgt
    43081 acttcacgaa gcaagtagtt ttcaacagat aatacatcgc gaacttgcaa caattgtttt
    43141 ggatcgattg atccttctgt caatggtgca ccacggtgga tcatatcgcc ttctgctact
    43201 ttcatacgtg ctgtataagg aacagtatac gtacgtgtat ctgtttttcc tttgattgtt
    43261 acttctttgg tacgtgttgc aggatcttct gagatatcga tgacatcccc tgttacttct
    43321 gtgatcactg cttgcccttt cggattacgt gcttcaaaga tttcttggac acgaggaaga
    43381 ccttgagtga tatcgtctcc ggcaacccca cctgtatgga atgtacgcat cgtcaactga
    43441 gtaccaggtt caccgattga ttgagcggcg atcgtaccaa ctgcttctcc gacttcaacg
    43501 tcagagccag ttgcaaggtt gcgtccgtaa caatgtttgc agacaccatg ttttgtatta
    43561 catgtgaaga cagaacggat tgtcactgtt tcgacacctg catcaacgat ttgttttgcg
    43621 atgtcttcgg aaatcaattg gtttcctgca atgatcaatt catttgtttc aggatgacgt
    43681 acttctttac gggtgtaacg tcccactaaa cgatcttcta atgattcgat gatttcattt
    43741 ccctcgcgga tggcttggat ttcaagacct cggtcagtac cgcaatcttc ttcacggatg
    43801 attacatctt gggccacgtc aaccagacga cgagtcaagt aacctgaatc ggcagtcttc
    43861 aaggctgtat cggtcatccc tttacgagcc ccgtgagttg agataaacat ttccaagacg
    43921 gatagtcctt cacggaagtt cgaaatgatt ggcaattcca tgattcgacc attaggagcg
    43981 gccatcaaac cacgcattcc ggcaagctgt gtaaagttgg aaatgttacc acgagctcca
    44041 gaatcagaca tcatgaagat tggatttttc gcttccaaac cttccatcag tttttgttgg
    44101 atgctgtctt ttgcagcatt ccaaacagca atgacacgtt cataacgttc gtcatctgtg
    44161 atcagaccac gacggaattg ttttgtaata gtttcaactt gtttatgggc attttcaatg
    44221 atttcttgtt tttcattcag tacactgatg tcagcgatcc ctactgtgat accggcatgt
    44281 gtcgaatgtt tgtaccctaa gtctttcata cggtcaagca tcttagaagt ttcttttact
    44341 ttgaatcgtt tgaagacttc tgcgatgatg tttcctaagt ttttcttctt gaacggtaat
    44401 actaattctt gctctttgat atgtgcagga atatcagtac cagcttcaac aaagtatttg
    44461 tccggtgttt ggacggtcaa gttgaagtct gttggttcat tcagataagg gaattcagga
    44521 ggcatgatct cgttgaagat gatcttacca actgttgtga tcatcgtacg ttctttttgc
    44581 cattcagtaa atggtttttc acctaatgag ttagggttca caccgatacg tgaatgtaaa
    44641 tgaacatatc cgttgcgcca tgcgataacg gcttcgtttt gatctctgaa gaccattcct
    44701 tcgccttcgc gtccttcttc ttccattgtc aagtagtagt tacctagaac catatcttga
    44761 gaaggagtaa caactggttt accatcttta gggttcaaga tgttttgagc agctaacatc
    44821 aacatacgtg cttctgcttg tgcttcttca ttcaatggaa cgtggacagc catttggtct
    44881 ccatcgaaat cggcattata agcttcacat acaagtggat gcaaacggat tgcgcgtcct
    44941 tgtactaaaa ctggttcgaa tgcttggata ccaagtcggt gaagcgtagg tgcccggttc
    45001 agcaatactg ggtgttcctt gattacgtct tctaaaacat cccatacttc gtcttcttga
    45061 cgttcgattt tacgtttcgc atttttgatg tttgaagcta gttcgcgttg aacaagctca
    45121 cgcatcacga atggtttgaa taattcaatg gccatttctt ttggaagtcc acattggtac
    45181 atcttcaaga aaggtccaac aacgataacg gaacgacctg agtagtcgac acgtttacct
    45241 agcaagtttt gacggaaacg accttgtttc cctttcaaca tatgagaaag agatttcaat
    45301 gggcggttac ctggtccagt aactggacgt ccgcgacgac cgttatcgat caatgcatct
    45361 actgcttctt gcagcatacg tttttcattt tgaacgatga ttccaggtgc attcaagtct
    45421 aacaaacgtt tcaaacggtt attacggttg attacacgac ggtaaagatc attcaagtca
    45481 cttgttgcaa aacgtccacc ttctaattga accattgggc gtaaatctgg tggaataaca
    45541 gggataacgt ccataaccat ccagcttggt tgatttcctg aagcgcggaa tgcttctaaa
    45601 atatccaaac ggcggattgc acgtgtacgt ttttgtcctt gtgcagattt caattcttct
    45661 ttcaattcgg ctgcttctgc atctagatca acattatcaa gtaattgttt aatcgcttct
    45721 gcacccatag cagcttggaa ttcttgtcca tattgttcac gtttttcgcg atattcgcgt
    45781 tctgtcaaca attgtttttt ctctaaattc gtatttcctg gttcgatgac tacatatgaa
    45841 gcaaaataaa tgatttcttc caaagcgcgt gggctcatgt ctaatacaag acccatacgt
    45901 gaaggaatcc ctttaaagta ccagatatgt gaaacaggag ctgctaattc aatatgtccc
    45961 atgcgttcac ggcgaacttt cgaacgagta acttccactc cgcatcgatc acaaacgatt
    46021 cctttataac ggatacgttt gtattttccg caggcacatt cccagtcttt tgtaggacca
    46081 aaaatccgct cacagaacaa cccttcgcgt tcaggtttta aggtacgata gttaatcgtc
    46141 tcaggttttt ttacttcacc gtaagaccag cttctgattt tttcgggaga agccaaacct
    46201 atttgcatac tttcgaattt atttacatcg atcaaaaggg gttccctcca tttcatttaa
    46261 tggcaaaccg caagacggct gatcttcgac cgccttgcag ctcatagacc ggattagtct
    46321 aaattatctt ctgcggtttc aaagttttgg atgacatcgt ctttttcatc ttccacttgt
    46381 tcagcagctt tcttttctaa ttctttggca gtttgctgtt cggcaaattt tgtcaaagca
    46441 tcaacagtga tcaaatcgtc gtcttcatcg tccatgtcgc gaagttcgat ctctgtttct
    46501 tcgatatcca agacacgcat gtccagacct agtgattgca attctttcac caatacgcgg
    46561 aatgattccg gtacacctgg ttttggaatt ggttcaccct tgacgattgc ttcgtatgtt
    46621 ttcacacgtc cgactacgtc atctgatttg tatgtcaaga tttcttgtaa agtataagcc
    46681 gcaccgtaag cttccagtgc ccatacttcc atttcaccaa aacgttgtcc accaaattga
    46741 gctttacctc ccaatggttg ttgtgtaacc aatgagtaag gtccgattga acgtgcatgc
    46801 aatttgtcat cgaccatgtg agcaagtttg atcatgtaca tcacaccgac agacacacgt
    46861 ccatcaaatg gttcacctgt acgtccgtcg tacagaacag ttttcgcatc gctggccata
    46921 ccggcttcac gaactgtttc ccatacgtct tcatcacttg caccatcaaa tactggcgtt
    46981 gctacgtgga tacctaactg acgtgcagcc atacccaagt gtaattccaa tacttgcccg
    47041 atgttcatac gtgaaggcac ccctaaagga ttcagcatga tatcgattgg tgttccatca
    47101 ggtaggaatg gcatatcttc ttccggcata atacgggata caaccccttt atttccgtga
    47161 cgaccggcca ttttatcccc ttcatggatt ttacgttttt gaacgatata aacacgaact
    47221 aacatgttta cgcctggtga caattcatct ccagcttcac gagtaaagat tttcacatcg
    47281 tgaacgatac cgccgccgcc atgtggtaca cgtaatgatg tatcgcggac ttcacgagct
    47341 ttttcgccaa agatcgcatg caatagacgt tcttctgcag ataattctgt tacccctttt
    47401 ggcgtgactt tccctacaag caaatcgcca tcttggactt ctgcaccaat acggatgata
    47461 cccatttcgt ctaaatcttt taatgcgtct tccccgacat tagggatttc gcgtgtgatt
    47521 tcttcaggtc ctaattttgt atcgcgggct tctgattcat attcttcaat atggatagaa
    47581 gtgtatacgt catcttttac caaacgacgg ctcatgatga tcgcatcttc atagttgtac
    47641 ccttcccaag tcatgaaacc aactaaaacg ttttggccta gagccatttc gccttgttcc
    47701 atagatggtc cgtctgccag agtatcccct ttttcgactt tctcacccaa atgaacgatt
    47761 ggacgttggt tgtagcttgt tccggagttt gaacgacgga attttgttac atcgtattta
    47821 tctaatgcac cgttgtcgcg gcgtacgcgg atttcagaag catcaacgta ttcaacgaca
    47881 ccatcatgtt tacataacaa agcagctcct gagtcatgcg ctgatttgta ttccatacca
    47941 gtaccaaccc atggtgcttg aggattgatc aacggcactg cttgacgctg catgttggca
    48001 cccatcaagg cacggttgga gtcatcgttt tccaagaaag gaatacatgc tgtcgcaacg
    48061 gcaactactt gtttaggtga tacgtccatg tagtctactt tatcaataga tacttctaag
    48121 ttttcacttt gagcacgagc cataacaacg tcttgagcaa atgttccatc ttcattcaat
    48181 gggctgtttg cttgggctac gatgtaatgg tcttcgatat cagctgtcaa gtagtcgatt
    48241 tggtcagtaa cacgacctgt ttcacggtct acacgacgat aaggtgtttc gataaatccg
    48301 aatttattta ctttcgcata actggacaaa ctattgatca acccgatgtt tgggccttca
    48361 ggagtttcga tcggacacat acggccatag tgggagtagt gaacgtcacg aacttcataa
    48421 ccggcgcggt cacgagtcaa tccgccaggt cctaaggcga aaagacgacg tttgtgtgtc
    48481 aattcgccaa gagggtttgt ttgatccatg aactgtgaca actgagaaga accaaagaat
    48541 tctttgatac ttgccacaac tggacggata ttgatcaatt gttgaggtgt caatgtttca
    48601 gtatcttgga tcgacattct ttcacgaacc acacgttcca tacgtgctag cccgatacgg
    48661 aattggtttt gtaaaagttc accgactgaa cggatacgac gatttcctaa gtggtcgata
    48721 tcatcgacat tgccgatacc ttccatcaag ttcaagaaat agctcattga agcaatgatg
    48781 tcggctggac gaaccgtttt tacagctgct tctggatagc cgtttccgat cacgtttact
    48841 tcacgttcag ggtctcttgg tgaaaatact ttgatgactt ggacagtcat tggatctgtg
    48901 accacaccgt cttctgatgg atagtaagtc actgaattta ggccattatc aatgaaagga
    48961 gctagtgttt ccatgacttg gtgagtcaga actgttcctt tttcaacgat gatctcgcct
    49021 gtttctggat caactaatgt ttcagctaat gtcagattca atagacgtgt tttcaaatct
    49081 aattttttgt ttactttgta acgaccaacg tttgctaagt cgtaacgttt tggatcgaag
    49141 aaacgagcat tcagcaagtt acgtgagctg tctgctgttt ttggttcgcc tggacgcaaa
    49201 cgttcgtaaa cgtctttcaa accttcttct gttcttgagt cgcttgcgtt tttatgcaag
    49261 tctttttcga ctgtattgcg taatgtttcg ctgtcgccga agatttcaaa gatcgtatca
    49321 tcggaaccaa atcctaacgc acgaactaat acggttaaag gaatcttacg tgtacggtcg
    49381 atacgtacat aagagatgtc ttttgcatca gtttccattt ctagccaagc tccacggtta
    49441 gggataacag tagaaccgaa tccttctttt ccgtttttgt cgacttttcc atggaaatag
    49501 acacctggtg aacggactaa ctgagaaacg attactcgct ctgccccgtt gatgatgaat
    49561 gttccttgtt ctgtcattaa tgggaaatca ccgaagaata cttcttgtgc tttgatttcg
    49621 ccagtctcgc ggtttgtcaa acgcaatgtt acatgtaatg gtgcagagta gtttgcatca
    49681 tgcgcacgag cttctgctac tgtatacttt ggttctttca attcataatc tacaaattcc
    49741 aaagatagat tgccattgaa gtcatcgatt ggcaaaatgt cttcaaacat ttctctaagt
    49801 ccctcatcta agaaccattg gtaagagtct gtttgaattt cgatcaaatt tggtaattcc
    49861 aacacttcac tgattcttgc gaaacttcta cgttcgcgat gttttccgta ttttactacg
    49921 tgtccagcca agctcttcac ccctctaaaa tgtcattcaa aaagactacc cgatcaattg
    49981 ttacaataat atttcaaata ttatttttag gtaacaacag acattttttg cggcttttag
    50041 gcaaaaaaaa accaaaaata gaacattctc ttgaaacctt acttcgtgag cttctacttt
    50101 tgtttcctta tattaaagcc gaaacggaca atatttcgtt tctgcctttt cttcatcaga
    50161 tagtttttgc aacttcatat actacactta ttttctataa aagtcaacac ttcctggcgt
    50221 ttcttctgct ttttcgcaac attttcttaa tgttttcaat tttatgtttt caattatctg
    50281 acaattctta attgacagac ctttttatct cggttatact ttagaaaatt cattttgtgg
    50341 aggaacttct atgcgaacca acatcaacca aatcgcacca acacaactga ataactttta
    50401 ctttagctac tttagatagg tttgtattca tcatgatgga tacaaacgtt aaacgacagt
    50461 ttgtatctat gatggctaaa gaactttgta ttgcagcaaa aagccacgta gacaaaatgc
    50521 taagtggctg agcagtgaaa atacaaagta aaagtatcaa gcattctact ttttcaattt
    50581 attttccgac ttttcaatcc atttggacat tttgtctgaa tggatttttt gtttcccaaa
    50641 attaaggagg aaaaagaaat gaaaaaaaat ataatcatcg gattaggcgc tgccctgcta
    50701 ctagctttag gaggttgcgc acaaaaagac aattccgcag aggcatcaga tggacaaaaa
    50761 acaattggcg tattgcaact tgtacaacat aactcgttag atgctgccta taaaggattc
    50821 aaagaaggat tagcagaaga agggtataaa gaaggcgata atctaacaat cgattatcaa
    50881 aatgcccaaa acaatcaaga caacctgaaa agtatgagtg agaaactcgt caaagaagat
    50941 cctgatttgc tacttggaat cgccactcca gcagcacaat ctttattaaa tgaaacaacc
    51001 actatcccga tgactgtcac agcggtcaca gacttggaac aagcccattt agtcacatcc
    51061 aatgaaaaac ctggcggcaa tgtgactggc acgacagata tggtgccaat cgaaaaacaa
    51121 atcggcttac tgttaaatat cgtgccagac gccaaaacaa tcggcatcat gtataacaac
    51181 ggtgaagcaa actctaagat ccaagctgat ttggcagaaa aagaattgaa aaaagcgggc
    51241 gtcaaagtca aagtactgac agcaaattcc acaaatgatg tccaacaagt gacgaaaagt
    51301 ctagctaaag atgtagatgg aatctatatt cctactgata acacgttcgc aagtgcggca
    51361 agtgttgtcg gtgaagtcgc aaaagaaaca aaaacacctg tcgttgctgg cgcagttgat
    51421 caagtcaaag acggcggtct agcaacagta ggaatcgact acgaaagctt gggcaaacaa
    51481 acagggatca tggcagcaaa aatcttagac ggcaagaatc caagtgaact tcctgtcgaa
    51541 acagcgaatg atttggaact gtatgtcaat aaagacatgg ccaaagcatt aggcatcaat
    51601 ccagacagca tcaaagaagc tgaataaaac acaggaggat tctcatgaca aatttgctct
    51661 ctcttttctt atcatctgca tcgcaagggg tcttatgggc cctacttgcg attggtgtat
    51721 acgtcacttt ccgtatcttg gacattgccg acttgactgc tgaaggaagc tttcctttag
    51781 gtgcagggat cgcggcagta agtattacaa atggctatca tccattgaca gcttgtcttc
    51841 taggcttttt agggagtgcg gcagcagggc ttgtttccgg actgcttcac acaaaattga
    51901 aaattcccgc ccttcttgca gggatcatca ccatgactgg tttatattct gtcacatccc
    51961 gtgtgatggg tgcgccgaac atctctttat tgggtcagcc aacgatcttt cattgggtcg
    52021 agtcattcgg cataacaaaa gacaacgctg tactgatcgt cggtctgctt tttgctttga
    52081 tcgttgtatg tttacttgtt ttgttcttac gtacagaaac aggacttgct attcgtgcaa
    52141 ctggcgataa tctggcaatg agcgaagcaa acgggatcaa cacagataat atgaagatca
    52201 tcggttatat gatttctaat ggatgcattg ctctttctgg ctccttgctt gcgcaaaaca
    52261 acggctttgc tgatttaaat tctggtattg gaacgatcgt aattggactt gcttctatta
    52321 tcatcgcaga agttttgtta cgtaaccagc cactatttct ccgtctcttg actgtcgttt
    52381 taggtgcggt catttatcgt tttattttag cgttagtctt cgaactgaat gttgaaccaa
    52441 gtgattcgaa acttgcttct gctttcgtgc tagtgatctg tctttctttc ccgcagatcc
    52501 agcaaaaatt ccatttacct caaaaaaaga aaggcggtag tgtcaaatga atgacgtctt
    52561 aacattggaa aatctccatc atacctttga aaaaggaacg atcaacgaaa atcatgtcct
    52621 gaaaggcatt aatctttcct tagatcccgg cgacttcgtg acgatcatcg gtggaaatgg
    52681 ggctggtaaa tctactttgc tgaacagcat cgccggtaca ttttctgtcg atcagggtca
    52741 aattttattg aatggaaaaa atatcacgaa aaaatctgtt gtcgaacgtt cgaaatccat
    52801 cagtcgcgta ttccaagatc ctaaactagg gacagccgtt cgtttaacgg tagaagaaaa
    52861 tcttgctctt gctatgaaac gaggaaaaaa acgcggcttc ttccgtggtg tcaaaccaca
    52921 agaccgaaca tttttcaaag accagctggt tcggctaaat ttggggttgg aaaatcgttt
    52981 atcctcagaa atcggtttgc tgtctggagg acaacgtcaa gctattacgt tattgatggc
    53041 cacattacag cgtccagaac tgatcttatt agatgaacac actgcagcgc ttgaccctgc
    53101 tacttccaaa acggtgatgg aattgacaga aaagctgatc actgagcaga atctcactgc
    53161 ttttatggtc actcatgaca tggaagacgc gatccgctat gggagtcgac tgatcatgct
    53221 gcatcaagga aggatcgtcg tagatatcca gcaagaggaa aaacagcagc tcacagtgcc
    53281 ccaattatta gcgttgttca aacaaaacag cggcacggca ttaaaagacg atcaagtact
    53341 tttatcttca taatcagaaa gaggatggga caaaaaatga acgcccaccc tcttcttttt
    53401 tctctttcct tctttcgttt ttgctttatg tatcaaccgt tgtttcttcg aaaactattt
    53461 tgttctctcc ttcttcctga tagaatggat gggaaaggag cttgatgcca tgacaacgaa
    53521 agacaaggta cttcaattat tgaaaaagac accagatttt ctttccggag aaaagttggc
    53581 acagcaactg gaagtttccc ggacaagtat ttggaaagcc atcaaagaat tggaaaaggc
    53641 aggctatcgt tttgagcacg ggcctacagg gtatcgttac ctgccctctg acgtactaga
    53701 tgcaaaagaa atccagcaag agctacggtc gtttattcct gatttgaaag tacaaacgat
    53761 gttgacttct gaatctacga tgaaagatgc caaactggca gcagctcaag gagattctgt
    53821 ttcgaagtta tttgttgctg atacacaaga acaagctcgt ggacgttttg gacggccttt
    53881 tttcgctgaa cctggacgag gaatctacat gagtctcttg ctccatccag acaaacggtt
    53941 tgatgaattg cctcaatata cgatcatcgc agccagtgcc tgtgtgaaag ccattgaatc
    54001 tgtaaccggt cgttctgctt cgatcaaatg ggtcaatgat atctacatgg atggaaaaaa
    54061 agtctgtggg attttatctg aagcagtcag tgatatggaa agcggcagga tcagtcatat
    54121 catcattggg atcgggctta atttttctgt tcctcaaaat cattttccag ctgatctcca
    54181 agaaaaagcc atctctgtct ttcccgacgg acaagctagt gtcacaagga atcagctaat
    54241 cagcaaaatc tggcaagaat tgttcactta tctttctcac ccagaaaaag cgttggactt
    54301 ctataaagaa aaatcattcg tattgggaaa aaccgtgtcg ttcaatcaaa aaggaacgac
    54361 ttatgtcggt cttgcaaaag aaatcggtga tcatggcgaa ctgatcgtcc aaacaaatga
    54421 acagaagatg agtttgtctt ctggcgaaat cagtctcaca tctatccgta cgcaataatt
    54481 atcagatttc acaaaaggac acctgatctc atacagtgtc cttttttctg aattctcttc
    54541 aaaagactct ccttattcta tcagctgaca gtttctctat cctctagaaa aaggtattct
    54601 aaaaatatct ataaagcatg gtacactttc tttaaatgaa tcaatgcaaa aaacaagaga
    54661 gtcatcagtt tacacgatca aaagagatag caggccgctt cctttttcaa tcttatagat
    54721 agaccatggg taacgataaa aacaaaaaag aacttgcgac ttattttgcc gtaagttctt
    54781 ttttagctag tgccttaatc tcttaatccc aacaaacgtc tcgcatagat cacctgacca
    54841 gagtgcatag cagcatcatc aataatagaa acgagacgca ttcctcgtgt gactggtggt
    54901 gtccagttct cgtcaattac ttcatctagc tcggaaggtt ccagccttct taagtaagaa
    54961 atagcaaaat cagcagctcc tcgcaagtat cctagcagat cttctatttg attagcttgg
    55021 atctgctttg cttgttccag actatgcttc caatcttgtt cgttatctgc tatcgtcatc
    55081 ggaaaccggc tttcccagtc ttgactatgc caaattggag aagttcctgc taaatcagca
    55141 atctggaaat ctaattctcg agcggtatgc caagccagcc aagtcattga tttgatctgc
    55201 ggggctctat cttccactgg aaaacgattg gcctcctcaa tagagacgcc ttcaaacaaa
    55261 cgttcaaacc gatcgtatgc ccgatccaca ctctcgcata gcatatctaa ataatccatt
    55321 tattttcctc ctttttattt atcctactta ctttttccta attctaggat acctacttat
    55381 atgttactac acacccttat tttttacact ttaacagtca ccatcatcaa tagtttggag
    55441 attgaaagaa aaagatagtg tcgaactatc aattgaacaa gaagcaacaa tatgaacgtt
    55501 tcattaatat tctttaaata aacaatgatt tttcaaacga acagtttaag actaggagaa
    55561 aaagagtata ataggaaaat gtttgaaagg aaaggaaggg gaaaaatgaa aaaaagggca
    55621 agtttactag tcctagttgc tttgttgttc aatatctttt cgtatggtgt ggccgtttca
    55681 gcggaaacat acattcctaa agaccctggg aatatttata atgatctaac tggtaactat
    55741 ggcttgttag gaattgctag tcaattccac gtatttgcta aaaataagac aactgtgaat
    55801 gcacatacag acggaaatat agcaacacat gaacttgatg caaaaaataa ttttggtaca
    55861 gagcttcatg aaggtttatt gaaccaagaa ataaattata tacaaaaaac tgattctttc
    55921 gctaattctt caggcatacc tacaggtagc acaagaatga ataaatttgt cgttggcagt
    55981 aacgtggatg tagcacttca agatggtcat cctacagtca atggatccag gcttgatcac
    56041 ttaactccag atgattttta taaagatcgt gctgggcatg aatatattga tttcgagcag
    56101 gaatttgcta aattgaatgt agcagcaaat gatcttgcaa cgatcactcc agctaaaaca
    56161 tatactgctg cagattttcc agacatgaac aatcggacaa tcgatttaac tgatttatca
    56221 gataccgggt ttttattggt aaatatcgat gcagaagtgt taacgatgaa tacgccactt
    56281 caaatcatta atccaaatga tcaagtagtt gtatttaatg tcatcaacag ttcttctgca
    56341 ttgaacgtac agtcaccaat caaatacaat gatcgttcaa atcatgaaac agaagatttt
    56401 tcggatgcga atatctcttg gaattttgga aatgagatga ctgatttgac aatcagtgct
    56461 ccttttcaag gaacaatcct tgcgcctaat gctactatcc gcattactca aaaccaagac
    56521 ggaacgatta taggaacaaa tgtgatttta gatgcagcta ccaatcgttg ggatcctaac
    56581 gaaatattta tcagcgacaa tggtacagat acgacagaca caagcgacag tacagataca
    56641 tctaccacaa gtgatagctc agattcatca acttcaagcg acagtacaga tactacctct
    56701 accacaagtg atagcacgga tacatcagct tcaagcgaca gtacagatac tacctctacc
    56761 acaagtgata gcacggacac atcagcttca agtgacagta cagatactac ctctaccaca
    56821 agtgatagca cggacacgtc agcttcaagc gacagtacgg atacatctac cacaacaagt
    56881 gatagcacgg acacgtcagc ttcaagtgac agtacagata ctacctctac cacaagtgat
    56941 agctcagatt catctaccac tacaagtgat agcacggaca cgtcagcttc aagtgacagt
    57001 acagatacat cctctaccac aagtgatagc tcagattcat caacttcaag cgatagtaca
    57061 gacacgtcgt ctaccacaag cgatacacgt catgcaagtg tctccttctc aaaaacaagt
    57121 tcggataaca ggacgaactt taacttaact aataaaacaa gcaatgacaa tggaaacaaa
    57181 tcaaaaagag cacttcctaa aactggaagt caatcgaata attggataac actcgcaggc
    57241 gttatattac ttgtaatcgg tttaagaatc acttttatga gttataagaa atcgaaaagg
    57301 taaaaaaata ttcaagataa aaaagagcaa cgtcgctaac ggacgttgct ctttattttt
    57361 gctttttatc ataaatacaa gaactacaat tcaatttgtc aaaaaacacg tagatttcct
    57421 tctgagaaat ttatttacgt atcgaacctt tccctattca gtctttgcga tccaaaatca
    57481 gttgggtaag ggaaaagaga ttctcttttg ttcgaagaga ggtggcaggt aatttcttta
    57541 tttccttcaa agccttttct gtgtaagagg ccgctaactt cctagcttct tccacgcctc
    57601 ctgtatgttc aacgattttg cgtacggcgt cgacatcttc ttctgtcatt gccgctttct
    57661 tctctaaata aggtagtagc tttggtttgt ttttttgcaa agagtagatc aacggtaaag
    57721 aatagacccc ttgacgcatg tcttctagta caggtttgcc gatttcctgg ctctcttttg
    57781 tataatctaa aatatcatcg ataatctgaa aggccatccc gatagaaagt ccgatatctc
    57841 ctgctttttt tgcgaagcgc tcgcttgttc cactttcaaa agcgccaaca gaacaactta
    57901 attggaacag ttcagctgtc ttacctgaaa tattttccaa atattctttt acagaaagtt
    57961 cataattata gcgatcatcc atctgaccta attcgccatt caatactttt tccatactgc
    58021 gagaattcaa ttggagactt ttcaaggaag tggagtaatc agacaatagt ttaaaacagc
    58081 agacaaataa atagtctcct gcatagacag aaacgacatt accaaactga ctacggatat
    58141 taggctgacc acgtcgcaga tccgcttcat caacgatatc atcatggatc agtgtggccg
    58201 tatggagcat ttcgatagaa gctgccaaag cgatggcttt gtctcgatct tgctctggtc
    58261 caaattgtga gaacaatagc tgataggcag gacgcaacag ctttccgccg gcatggatcg
    58321 tttctttgat tgcttgttcg acaggtttgt ttttcaggcg gacagtttct tccatccgtt
    58381 ttagtgtttc tgtcaattct ttacttaaag caggatagtt ttcccacatt ggatgtagct
    58441 tcataaaaaa actccttgtg tgacgattat tttttggtaa acattgggct ccatttttgt
    58501 ttggttccct gctcataatc tttttggaat cgttgaagtg tctgcacatg tcgtaaaaga
    58561 taattcgctg cgatcccgat tgcaatccct gataaaatcc ctaaaactga aaggactggc
    58621 aagtacaaca tgactgtcca tgattgtgca atgaaagaag ccatcaaaag ctgtccgaca
    58681 ttatgcatga aaccgccggc cgcactaatt ccgatgatac tgacacgttt tggtcctaat
    58741 tgcttgacca ataacattcc aaaataacta agcaaagcac cactcatact ataaaggaat
    58801 gtggaaatcg ttccgcctag caaagtagtc aggaatagtc gtagccaaag tagtaagaag
    58861 ctgtctcgtt ttttcatggt aaaaatggca acgatcgtga ttagattggc taagcctagt
    58921 tttgcaccag gcgcaaaaga aaaaggataa gggatcatat tttccaataa accaatgatc
    58981 actccttgtg caacaagtag cgaaatataa atcatttttt gtaatttact catggtgtgt
    59041 gaaggtctaa taaatcagac tgtcttcgtc acctccatct gttgaacgga cttcgatcac
    59101 taatttatgt ggcaaacaga cgatggtttc gccatttttc gttgcccagc ctcgacgtac
    59161 gcagatctgg tcatcgcaat ctgcttcttt tatccgtact cgatcgccat ctatctcgat
    59221 caagttataa tctccgtgtt catctttgta agtatatgtg ttgctctctt ctccagccat
    59281 caaagggaat gttttgattt ctgtgccatc cacacgcagt accgcttctt tttctgctgt
    59341 tgcggtgttt tgctgaagac caaaaatcat gactggtaaa aaagaaagaa cagtcaaaag
    59401 caaaataata aaaacatccc aaggtttgag cagacttttt tcagcaaatt ctttaaggct
    59461 catttttgtt ctcctttttc cagattaact cacccaattt tagcataaaa acaagaggtt
    59521 gtgacacctg tgtcttgctt tgagtaataa gaacgaagaa tagaaaacag ctttccatgt
    59581 tttctaattc tttgggctta ttaccgagaa gcagcaggtg gaacaccgtt tataacaaga
    59641 ggttgtgaca gaagtgggca acttcaagaa ataagaagga atttacgaaa attacttttc
    59701 aagtttttgt gaaatttcgg cttatttttc gaagaagcta cttctggaac accgtttata
    59761 acaagaggtt gtaacagagg ttgtgacacc tgtgtcttgc tcatggaggc ttatctcggg
    59821 catcttattc ctttaatttt acataaaaag gaggctgtga cggtttgtct cagccccttt
    59881 ctattgaaat cttgcattca aataacgttc tttatctatt tatttcttgc cgtactggga
    59941 acttggtcta ccgtaccacc aattacctag tgtacgttgt agccatggaa ttacccagcg
    60001 atccaaccca atcgcacgtc cggaaccgtt catcaatgcg aaagcaacaa aaatgaacca
    60061 aatgtttacc cagtaaaaca tgcctgataa gcagaacgtg atcaccaata caatcgttgt
    60121 cgcactgcat agccatgtga ataatccagc aatcaatgct aatgccaagg caatttcaaa
    60181 gaataccatg aatttttgga agaacattgc tacatcattg tttggcatga tcacttgcat
    60241 gatctttgtg aaccagtctg gtgacttctc aatcacagcc attggttctt caccgtatgc
    60301 ataactcaaa ccaaaatgtg cagcttgagt cgctgcttct ccggcacttg cccctgctcc
    60361 gctggcagct gtggttgcat caccagcagc agaagcacca ctggcaacat ctgttacatt
    60421 gtattcccat gtccaaggga acacactgtt tccagtgaac catgatcctt caccaaacca
    60481 agtacttggt ttgaacactt caccattccc aatgattttt ttggaagctt caacgaacca
    60541 aactaaacca tagaaaatac gaagtggcac actccataag acattgccgt aacgagaaga
    60601 atgtcctcga gtcacgttgc gatcatcttt gatatggaaa aactcatgca ttaaatattg
    60661 gaacatataa taaccagaac gaatatcaaa gaagtatttc aaattcacga tatgtttcat
    60721 tacgatagct aaaaatccgc ttaaatggat cttatcaaat aggttagcta ccccccattt
    60781 ggcaccaata gaaaccataa atccttgata gtttccttta aatttatgct tttctccgcc
    60841 tttgatcgaa gccacgatat tcgctgcggc tgtgtgtcct gtttgttcag cagcttgaac
    60901 gatctgcggt gtcggtgttc ctgggaattc ttcataaaag actaaatcac caatgatata
    60961 gatgttttta tcttcgtagc cttttgcctg catatattca ttggcgatca accgctgtcc
    61021 gcgtgctgat tctaatccaa agtcagcagc gtcagaagtt cctttgacac cagctgtcca
    61081 aatcagtgtg tgagtcggaa tgttgcgtcc gtctttcaat ttgatatgat cagcagccac
    61141 ttctacgatt ggtgcattca ataataattc cacgttgtgc ttacgcaaat agcgttcagc
    61201 ttttgcagca tcatttcgat ccaacatatt caagatcgtc ggcattgcct ctacgaccat
    61261 cagtgtgatt tcgtttggat ctaatttata atctttggct aggcgatttt tccagtcgat
    61321 cagttcccca atcatttcaa taccggtaaa tccagaacca cagacaacga aagtcagcat
    61381 ggctttacgc agttcatcat ctggttccaa tgcagctttt gctactgtct tctcaatatg
    61441 ttcccgaatc cttacagaat cttcaaatga ccaaagggtg aatccgtgtg ctttgacacc
    61501 aggtgtacca aagtcattcg gctctccgcc cattccaagg atcagctgat caaaaggata
    61561 ggaacctaat ttggtcttga cgatttttcg ttctttatcg ataccgatta cagtgtctgt
    61621 gacaagttgt acattctttt gacgagcaaa caaatgctgc agatcgtatt ggattgcttc
    61681 tggttctaca cgtccgccag ctacttcatg caactcggtc atcatagtat ggtacgaatg
    61741 acgatcgatc agagtaattg ctacatcttc ttttttcagt ttctttgcca agtattttgt
    61801 agctgaaaca ccggcatatc ctgctcctac aacgacaata ttttgctttg ccattgatca
    61861 tccgctcctt atagactatc tatataatga atatatgata attcttttag tttgatactt
    61921 attacacaat ctccatatat tatatagatg ttctgttctt ttgtctaact ccttttggat
    61981 ttttttcaaa ttttaaaata aagcgttttt tcacgaaatt tgctgaaaga aaacgtttga
    62041 aatattacat gggttattta tcaaaaatag ttgacttata ggctaaaaag attagaatgt
    62101 ataatgaatc acaaagaaaa attgtggact agaaatggaa tggtggggta ttaaaatgaa
    62161 gaaaaaacgt tttgtaactg gatttgccgt attagcattt tcagctctag tgttaggcgc
    62221 ttgcggcgca gatgacaacg gaagctcaaa ctcttcttct gaatcatcta cagcacaatc
    62281 ttcgactgca aaaagcacaa cagaatcatc tgcaaaagtt gtagctggcg gagatttgca
    62341 agacggcaca tataaattag aagaaaaaaa ttattcaaat ggttaccgtg cagtctttga
    62401 aatggttgta aaagacggca aaatcactga atcaaaatat gataacgtca atgaaaacgg
    62461 cgaatcaaaa acaaaagatg cagaatacaa caaaaacatg gaagcaaaat ctggcacaaa
    62521 cccagaaaaa tacattcctg agttgaatga ccaattctta aaagcacaaa gcgcaagcgg
    62581 tgtggaagtc gtaactggag ctactcactc atctgaaagc ttccaaaact acgcacaaca
    62641 attgatccaa gctgctcaag ctggtaacac agatacaatc gaaatcgaca atggtgctga
    62701 tttgaaagac ggcacttaca agcttgaaga aaagaactac tctaacggct accgtgtgca
    62761 attcgaaatg acagttgctg gcggcaaagt aactgaatca aactttgatt atatcgacaa
    62821 agacggtaaa tcaaaacaag atgatacaga atataatgaa aatatgaaag caaaaagcgg
    62881 tacagaacca aaaacttaca tccctactct gaacgacgaa ttcgtcaaag caatgggcga
    62941 agaagatggc tcacctgcta atgtagaagt tgttacaggt gctacacaca gctcacattc
    63001 attcatcatg tacgcacaac aattagtgaa tgcagctgaa aaaggcgaca ctcaaacaat
    63061 cgaagtagat aatatcgtaa cagaaaaata atcacataat catactaata aaagttggag
    63121 ggtgggacga tagccagatt aggcagtcgt ctcacctttc aaaatgaaga gaggaaaaag
    63181 atgcggaaaa aactactatt ttccttaatc acactgggca tctcttttat ggtgctaact
    63241 ggctgcagca actcagcaaa taaaacaacc actgaaagtt cagcagctac caagatattg
    63301 aaagatccat attctgatga acagttcttg ttagggactt acgttcgtat ccgtgtgtat
    63361 gatgaaggca aagaatcagc attgaaacct gccttcgatc gagtaaaaga acttggtgat
    63421 aaaatcacga tcaatcaaaa aggttctgag atcgatgaag tgaatgagca agctgggatc
    63481 aaaccagtaa aagtttctga tgacgtctac acgttagtca agcgggccta cgaatatagc
    63541 caagattctc aaggcggatt cgatatggcg attggtgcaa tcacacaatt atggcgaatc
    63601 ggttttgatg acgccagaaa accttcccaa gaagaaatcg atcaggcatt gaaattagtg
    63661 gattatcata agatcgaact aaatgacaaa gaaaaaactg tttatctaaa agaaaaagga
    63721 atgatcatcg atttaggtgc aatcgccaaa ggttacatta cggacgaagt agtgaaagtc
    63781 ttgaaaaaac aaggagtgac cactgccatc gttgacttgg gcggtaatgt ctatgtctta
    63841 ggccacagcc caagaggcga aaaccaagac tggacagtcg gcatccaaga tccgaacatg
    63901 gctcgcggat ctgttttagg ttctattaaa gaacggaaca aaacattagt tacctctgga
    63961 atttacgagc gttatttaga agtagatggc aaaaaatacc atcatttgtt tgatccaaaa
    64021 acgggttatc cgttcgacaa tgatatcgca agtgtcacga tcataacaga taaatcaatt
    64081 gatggtgacg ggttgtctac agcagtcttt tcaatgggtg tgaaaaaagg actggaatac
    64141 gtcgaaagcg aattgaataa cgggacggaa gcgatcttcg tgacaaaaga cgataaagta
    64201 tatgtgaccg atccaatcaa agacaccttc aaattatcgg aggactccca ttacacgatg
    64261 ggtgaccgtt ctgaactaaa ataaggagta cgaaccatga cactaaaaat ctttttagaa
    64321 gtagttgaaa tacgaacaaa ggtggctagt gtatttcctt ttgcggtagg ggtattattc
    64381 tctatcgctt tttttcatga gatacattgg ctaaacactt ttttattttt tattggaatg
    64441 ctagtttttg atttagcgac taccgctatc aataattaca tggattatga aaaggctcat
    64501 tctgaagtat ataagtatga agaaaatgtc attggccgca gaaatctatc tcctgtattg
    64561 attcgaaaca tgattttagc tatgattgca tttgtttttg ttatcggcgt tattctaacg
    64621 atcaatacgg gttggctttt acttttgatg ggatttatct gttgttttat tggagtattc
    64681 tatacattcg gaccgattcc tttatctcga atgcctttag gggaaatttt cagtggggtg
    64741 actatgggcc ttggaatttt tgccatggtc gtttatgtca atacattcgg ttcagatgtc
    64801 tatgatctga cagtcaactt ttcatctgga caatttgctt tggtaggaaa tctttgggct
    64861 atagcagcaa tcgtattagc ttccttaccc ttggtgttta cgattgccaa tatcatgttg
    64921 gctaataatt tgcgggatct tgaccgtgat attgaaaatc atcgctatac actagttttt
    64981 tatatcggac gtcctgcggg aacagtctta ttccagctat tgatgtatgc ttgctatttc
    65041 gtgattttaa tggggttgtt gagcggtatc tatgaatggc cgatcttggt caccttcttg
    65101 accttgccaa ttgtgaagaa gcatttggat caattcaagc aaacgttacc ccagcctatc
    65161 agtttcagct attccatcaa aaatatggtc ttattcaatg ccagttatgt attggggcta
    65221 ttactaacaa tcattatgca agccatttaa cagcatgaag aggttgtgaa aaaactgccc
    65281 tgcatcaagt aataagaaca gccaaataaa aatagctcct tatatttttc gtttggttgg
    65341 gcttattacc gcagatgcaa gcttttgaac accgtttatc aggaggttgt gaaaaagtcg
    65401 cttagtttcg agtattaaga aaaattttgt gaaaatggct ttccacattt ttgcataaat
    65461 ttggcttaat accgagaaac tggcttttga acaccgttta tcagaggttg taaaatcagt
    65521 gttttgtcct gagtattaga gaaacaaatg gaaaaatagt tcctcatatt ttgccgtttt
    65581 ttgagctaat accgaaggac agctgattga acactatttg ttcggaaaaa gtgactaact
    65641 atgacacaat ttttttcaca gtcccttttt tcacttgatt tgattcgtac cagcgaactt
    65701 gacgagaact ttcttggttt ggtaactata tggtattctt ttaacatcct cgtttgcttc
    65761 ttctaattta tttatacaaa gtcacacttt tttaaacatc tgttcttcga tacatttcta
    65821 tttcttttaa acatcgatac caatattttg aacttaagag tgcataccaa atggattcat
    65881 ttactcttcg tcagttacga agataatcaa aatctccaac ttccctactt atttcgtttt
    65941 gagaattatc gaagcaatct tacataaata actaaaaaac aaaaaaccag aaaatcagta
    66001 tactgatttt ctggttttac atggtttgtt caataaaaag ctgttggaac tgttaatatt
    66061 aaattatcgc atcgttacga attcttccgc tcctgttgga tggatggcta ctgtattgtc
    66121 aaagtcttct ttagttgcac ccatcttgat agccacggca aaaccttgca gcatctcatc
    66181 gacaccaaca ccaatagcat gtaagccgac gattctttct tcttttccga cacagatcaa
    66241 tttcatttcg catttttggc gataatcatt taatgcaaag tacattgggg taaagcgtga
    66301 acgataaact ttcaattcat tttcgccata tttttccaat gcttcttctt ctgtcaaacc
    66361 aattgttgca attggtggat gcgtaaagac gactgtcgga acaagtttat agtcaagata
    66421 agaatctttc tttccattaa ataaacgttc tgataaacgt ctaccagctg cgattgcaac
    66481 aggagtcaga tctaatttac cgatcacatc accaacagca aaaatatgtt catccgttgt
    66541 attttggtat ttatctactt tgataaaccc ttttttgtcc aattccacat ttgtattttc
    66601 cagacctaat ttttcggtat tcggtacacg tccaccggca aaaagtacac aatcaccagt
    66661 taaggtttca ccattttcaa atagcaccgt atattcgtca ttgtttttag taatttcttt
    66721 agcaatatga tgtgcgtaag tttttattcc agcttcttgg tacatttgga tcaaattgtc
    66781 cgaaagcatt ttatcaaacg ttctaagtgg tcgttctttt cgatatgccc acatgacttc
    66841 actacctaaa ccacaaaata cacctgaaag ttcagccgca atgtatccag cacctaaaac
    66901 gattgctctc ttaggtaact ctgttaattc aaaaaatcca tttgaatcaa ttgcgtattc
    66961 tccaccagga atggtcattt tacttgcacg gcctccagta gcgatcaaga ttttaggagc
    67021 acgataggtt tcaccgttta cttcgatcgt ttgactatcg ataaaagtag cgtaaccttt
    67081 tatagcctcg acatgattgc tatctaatcc tctttgataa gcaccgtgta gaaaatcaat
    67141 atatttttct cgtctttcta ctagaccggc gaaatcaaca ttttttaaat ctgcttggat
    67201 accgtaactt gaggcatctc gttcaattgt ttccaaaatc gtacttgctt tccacataac
    67261 ttttttaggt acacaaccga cgttgacaca tgttccgccc aattcattcg cttcaatcag
    67321 caaaactttt gcgccatgca tccctgctct gtttgctgaa gcaataccgc cagagccgcc
    67381 accaattacg atgtaatcat atatttgcat tttgttcctc cttattgaag agatcaatca
    67441 aaacctttat ttaacgatcc tttttctaca gaaaacaagt gtaacacttt tcttgaattt
    67501 tgtatgcgaa gatgcttaaa acagggatat atcagctttt tccttattta cgttttcgga
    67561 tcatatctcc aggtttcacc ggctgtgcga ctggcatagt taaaatcatc attggatttg
    67621 gtgctcggtc aatggattcg ccttcttcat tatgcataac ttcaacggtt tgactgaaat
    67681 gactgaatcc tggaccataa aattcgattt catctcctac agaaaacaag tttctctgac
    67741 gtatcgtagc aatctgtgtt gcctcatcat aagataatac ttcaccgaca aatttatata
    67801 ctgggatttt acgacgttca ccgaataatt gttcgttttc agttggtgta ttgtagtaaa
    67861 aacctgtagc taattctcgt tgtgctactt tccataactc gtcgatccat tcttgcttgc
    67921 agacatagtt ttcaggatct tccatataac tgtctacagc cgctttatag acatttgaca
    67981 ccgtagatac ataatggatc gatttcattc ttccttcgat cttgaagctg tctacgccgt
    68041 tttcaatcaa ttctggaata tgttcgatca ttgacatatc cactgcactc atcgagaatt
    68101 cttcttccac ttcgcctgta tcagttaaac tgtttcgttc ttgaccaaaa ggcatatcga
    68161 acaatccata cttccagcga caagattgag aacatccgcc acggtttgca tcccgcatcg
    68221 acatatggtt ggacaatgtg catcgaccag aataagagat acacatggca ccatggataa
    68281 atgcttcgat ttcggtatcc gtatttttac gaatctctgc cacttcctcc attgaaactt
    68341 cacgagctaa aacgacacgt tccaaccctt cttctttcca gaattccaat gtctcaaaat
    68401 tagttgctga agcttgagtg gataaatgga tcggcagacc tggggcttct gtcgcacaaa
    68461 tttcgatcaa agctggatca gaaacaatca ctgcagaaat accgacatca cgcaaactgc
    68521 ggaaaaattc ccctgctcca tcttcatttc cttcatgggt gaccatatta gcagcaacgt
    68581 ataccttcgc atcatgttct tttgcaaaag caactccttc agccatttct tcataagtaa
    68641 aattacctgc acggcttctt aaaccatatg cattcccgcc aatatatact gcatctgctc
    68701 cataatggat cgcggttttt aacttttcca gtgttcctgc tggcgctagg atttctggtc
    68761 gtttcaattt tctttttact gtcatttctt tcatcatact ccttatttga tagcagaagg
    68821 atcaatataa aagaatcctg tatctaattc acggttttca ggatgcaatt tactgatttc
    68881 gctagtcatt ttttccgctt tttcttgatc ccagctacct tctaaaattt gtttttttgc
    68941 ttcggcgaat agtcgagtga tgtttacgaa tttttcgcct ggagtaaata atccgtccaa
    69001 tttccatgta cagtaatgat gctgataaag ttcattcaat tcattcgaga gattcagatc
    69061 attgctggca aaaatatgtg tgccatgact atcttcataa atagaataat gtgtctcttc
    69121 ttttttaggt tccgagataa aaagacctct ttcacgatct ttttgttcgt cttgtttcgt
    69181 atagttatag taattctgta gcagtggacg tttggattga tggatgcatg tagcaccata
    69241 cacaagggtt tctacaggaa tatcgagttt ttcttccatc gccttcatct cttcaaaagg
    69301 aacttcacga gcaagtactg ctccaactgc gccttttttc gcccagaaat tgatttgacg
    69361 tgcgctcgtt actaatgttt cagcatcata aatatacggt atacgcaatt caggattttt
    69421 tttcatcgta taaataatac ctgtatcacc aactgtgatc acatctacgt ttatttcttt
    69481 taaaaaagcc aaatattcag gtacattttt cattttttca ggatgaatga tcccatttac
    69541 agcaatattc gcttttttac catacttgtg tgctaattct accaattgtc gctgttcttc
    69601 tcgtgtaaat gaagcaggca gacgcaatcc aaattgctct tcaccgaaat atagtgtatc
    69661 tgcacctgca gcaagcaact gttctgcttg ttcaatagtt tctactgtgg ttatgagttc
    69721 gatcataatt ttctcctcct acaacttcat aatagtagca tagctctaaa aactttccaa
    69781 tacttcttct atttaaagtc ggatttttga aaattatttc acaaaaaatc aaaataaagt
    69841 tcgatatatt ctgtccaaat ataaaaagag attgtgacaa aaatcttgtc acaacctctt
    69901 aatcaagtct tactattata aaaattcagc tacacaggcc aagtaactat agggaaccta
    69961 ctgtttcctt tttaggtccg cgaacattca atgtgatctt accttttgaa gcacctactg
    70021 ttacgtggtc acctaaacga atttctccgc caagcaaagc ctcgctcaat cgatcttcaa
    70081 tttctttttg aagtgcgcga cggattggac gtgcaccata ttcaggatca aatccagctt
    70141 tcccgatcac atcgattgca gatggtgtga ttttcacttg aatatcttgt tctttcaatc
    70201 gtttgataat cgctttgctc atgatttgga cgattgtatg gatttcatct ttactcaatg
    70261 aatggaagac gacagtctca tcgattcgat tcaagaattc aggtcggaaa gctttcttta
    70321 actcttctaa gatacgtttt tgcatggctt tgtgatcttt agtaacatct tggacattga
    70381 atccgacatt tttttcttct cgaatttgtg tcgctccgat atttgaagtc ataatcatga
    70441 ttgtatttct aaagtccact tttctacctt tagaatctgt taaatgacca tcatccaata
    70501 cttgcagaag taaattgaaa acgtctggat gtgctttctc cacttcatct aagagaatca
    70561 ctgaatatgg tttttgacga attttttctg tcaactgtcc accttcatca taccctacgt
    70621 atcctggagg agacccgatt aatcggcttg tactgtattt ttccataaat tctgacatat
    70681 caacacggat cagggcatct tcacttccaa acatgacttc tgaaagtgct ttggccaatt
    70741 ctgtttttcc gacaccagtt ggtccaagga acatgaatga accaattgga cgatcaggat
    70801 ctttcaatcc gcttcgtgca cggcggatcg cacgtgaaac tgctttgaca gcctcatctt
    70861 gaccaacgac acgttcatgc agaagtcctt ccagttctaa caagcgttcg ctttcttttt
    70921 tctccaactg ctgtagaggg acaccagtcc actccgatac aactgtagca acatcttctt
    70981 ctgttacacg atcagaataa ccttgctcct gttttgcttc aattgcagaa actttttgca
    71041 gctttttacg tagtgctttt tcttgtctgc gtaattgagc agcattttca aagtcttgtt
    71101 tttggatcgc tgcttccttt tcttgtacta gttcatcgat ttctagtttg atcacagttg
    71161 attttgttaa gtgatcggtt tgatccaaac ggactttcgc tgctgattca tcgatcaaat
    71221 caattgcttt atcgggtagt tgacgagaag tgatataacg aacagaaaga ttgactgctg
    71281 ctcgtacagc ttcatctgtg atctccactc catggtgctc ttcatatctt gtacgtaatc
    71341 cttgaagaat cacttctgct tcttcaggag ttggctcatc tacttgaatg cgagcaaaac
    71401 gtcgctctaa tgcagaatct ttttcgatat atttttgata ttcatctagg gtcgttgctc
    71461 cgatcgtttg taattctcct cgagctaacg ccggtttcaa gatattcgaa gcatcaattg
    71521 ctccttctgc tccacctgca ccaattaagg tatgcaattc atcaatgaat aagattactt
    71581 gaccatcatt atagatttcg tcgatgacct ttttcattcg atcttcaaat tcaccgcgat
    71641 atttcgtacc agcaaccaaa gatcccatat caagcatcat caggcgcttt tcttgcatgt
    71701 cttctggcac ttcacctaaa atgatttttt gagctaaccc ttcagcaatg gctgttttgc
    71761 ctacaccagg ttcacccacc agtacagggt tattctttgt ccgtcggcta agaatctgga
    71821 taagccgttt cacttctctc gaacgaccaa caactgggtc cagcttgttt tcttttgcta
    71881 atttcgtcaa atcacgtgct aatgaatcta gcgtaggtgt tccttgcggt gtttgccgtt
    71941 tatcttgtac atttacattt ctacgacgat tcattccttt tccagcagaa tcaccagcta
    72001 gccccatttt ttgtttcaga acttgacggg cttttgaaag gctgatacct aagttgatca
    72061 tgattcgagt agccatgata ctttcatctt ttaataagct catcaaaata tgttctgttc
    72121 caactttttg agaaccagtt ttcttcactt cgctgctagc taaagcaaaa acttgtttca
    72181 ttcttggtga atatggaaga aagactcctt tagggtaaga acggatacca ccataaccaa
    72241 tcagatgttc aatttcttca taaatttccg tttcattcaa atccatttca cgtaatactt
    72301 ttccagcaat tccattttgc tcgaccacta aggctagtaa aacatgttct gaactaactg
    72361 attgatgttt caaccgtttt gcttcttctt gtgcaatttc taatactgct tgggctcttt
    72421 cagtaaaaag ttcttccatc taatctcact tcccatcttc ataacttaaa cgttccagaa
    72481 atgctcggag aatccgagca cgtgtatgat cttcatattc attgaaattc aatgtgtttt
    72541 ttgcaattgc actcaacatc aagtttcctt ctttttttgt aattatttgg tcttcataaa
    72601 gtttttgaat aatagcaaaa gcatttttct cactgattgt atcatcaaat aactgattta
    72661 tctgctcaag taattgtttt ttatctgaaa tccttacttt tgcaattcgt atataaccac
    72721 caccaccacg tttgctttct actagataac cacgttggat ggtaaaacgg gtattaatca
    72781 catagttgat ttgtgaagga acacagttaa agaggtctgc catttcaatc cttcgaatct
    72841 cgatcatttc actattttcc agaattttct ttatatatga ttcaattaaa tccgaggtat
    72901 tctgatgtgc catcttattc attccctttg actaatattg accttaatta taacgaattt
    72961 gataatagaa agaaagaaga acgctttttg ttaaataaat cctttagaat caacaaaaaa
    73021 aaatacggaa tatactattc cgtatcgacg cgcccaagag gagtcgaacc cctaaccttt
    73081 tgatccgtag tcaaacactc tatccagttg agctatgggc gcatattcaa tttaaaaaaa
    73141 ttataaatca tttgaaaaca aaaagcaaga taaaaaaaat cgggaagaca ggattcgaac
    73201 ctgcgacccc ttggtcccaa accaagtgct ctaccaagct gagctacttc ccgtttaaaa
    73261 aataaaaaag ac
//
LOCUS       DAZKNV010000007        73026 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000007 DAZKNV010000000
VERSION     DAZKNV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.007"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            98..469
                     /locus_tag="ACG8M1_000489"
     CDS             98..469
                     /locus_tag="ACG8M1_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFQ0421230.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(743..1435)
                     /locus_tag="ACG8M1_000490"
     CDS             complement(743..1435)
                     /locus_tag="ACG8M1_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0421231.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(1438..2223)
                     /locus_tag="ACG8M1_000491"
     CDS             complement(1438..2223)
                     /locus_tag="ACG8M1_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0421232.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            2460..3860
                     /gene="lacG"
                     /locus_tag="ACG8M1_000492"
     CDS             2460..3860
                     /gene="lacG"
                     /locus_tag="ACG8M1_000492"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFQ0421233.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            3885..4202
                     /locus_tag="ACG8M1_000493"
     CDS             3885..4202
                     /locus_tag="ACG8M1_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0421234.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            4215..5888
                     /locus_tag="ACG8M1_000494"
     CDS             4215..5888
                     /locus_tag="ACG8M1_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFQ0421235.1"
                     /translation="MDGIIKQIEKGKAFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            5902..7533
                     /locus_tag="ACG8M1_000495"
     CDS             5902..7533
                     /locus_tag="ACG8M1_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFQ0421236.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(8024..9589)
                     /gene="guaA"
                     /locus_tag="ACG8M1_000496"
     CDS             complement(8024..9589)
                     /gene="guaA"
                     /locus_tag="ACG8M1_000496"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFQ0421237.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(9648..10571)
                     /gene="coaA"
                     /locus_tag="ACG8M1_000497"
     CDS             complement(9648..10571)
                     /gene="coaA"
                     /locus_tag="ACG8M1_000497"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFQ0421238.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            10767..11372
                     /locus_tag="ACG8M1_000498"
     CDS             10767..11372
                     /locus_tag="ACG8M1_000498"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0421239.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            11680..12696
                     /locus_tag="ACG8M1_000499"
     CDS             11680..12696
                     /locus_tag="ACG8M1_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0421240.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            12837..14138
                     /locus_tag="ACG8M1_000500"
     CDS             12837..14138
                     /locus_tag="ACG8M1_000500"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFQ0421241.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14184..14846
                     /gene="deoC"
                     /locus_tag="ACG8M1_000501"
     CDS             14184..14846
                     /gene="deoC"
                     /locus_tag="ACG8M1_000501"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFQ0421242.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            14867..15265
                     /locus_tag="ACG8M1_000502"
     CDS             14867..15265
                     /locus_tag="ACG8M1_000502"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFQ0421243.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15331..16413
                     /locus_tag="ACG8M1_000503"
     CDS             15331..16413
                     /locus_tag="ACG8M1_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0421244.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            16625..18187
                     /locus_tag="ACG8M1_000504"
     CDS             16625..18187
                     /locus_tag="ACG8M1_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421245.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18180..19313
                     /locus_tag="ACG8M1_000505"
     CDS             18180..19313
                     /locus_tag="ACG8M1_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421246.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19313..20269
                     /locus_tag="ACG8M1_000506"
     CDS             19313..20269
                     /locus_tag="ACG8M1_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421247.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20368..21534
                     /gene="deoB"
                     /locus_tag="ACG8M1_000507"
     CDS             20368..21534
                     /gene="deoB"
                     /locus_tag="ACG8M1_000507"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFQ0421248.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21558..22376
                     /locus_tag="ACG8M1_000508"
     CDS             21558..22376
                     /locus_tag="ACG8M1_000508"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFQ0421249.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22393..23100
                     /gene="deoD"
                     /locus_tag="ACG8M1_000509"
     CDS             22393..23100
                     /gene="deoD"
                     /locus_tag="ACG8M1_000509"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFQ0421250.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23398..24084)
                     /gene="gpmA"
                     /locus_tag="ACG8M1_000510"
     CDS             complement(23398..24084)
                     /gene="gpmA"
                     /locus_tag="ACG8M1_000510"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFQ0421251.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24256..24837)
                     /locus_tag="ACG8M1_000511"
     CDS             complement(24256..24837)
                     /locus_tag="ACG8M1_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0421252.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(24970..25653)
                     /gene="rpiA"
                     /locus_tag="ACG8M1_000512"
     CDS             complement(24970..25653)
                     /gene="rpiA"
                     /locus_tag="ACG8M1_000512"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFQ0421253.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            25972..26385
                     /gene="rpsL"
                     /locus_tag="ACG8M1_000513"
     CDS             25972..26385
                     /gene="rpsL"
                     /locus_tag="ACG8M1_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFQ0421254.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26469..26939
                     /gene="rpsG"
                     /locus_tag="ACG8M1_000514"
     CDS             26469..26939
                     /gene="rpsG"
                     /locus_tag="ACG8M1_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFQ0421255.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27033..29120
                     /gene="fusA"
                     /locus_tag="ACG8M1_000515"
     CDS             27033..29120
                     /gene="fusA"
                     /locus_tag="ACG8M1_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFQ0421256.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29292..30479
                     /gene="tuf"
                     /locus_tag="ACG8M1_000516"
     CDS             29292..30479
                     /gene="tuf"
                     /locus_tag="ACG8M1_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFQ0421257.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            30886..31194
                     /gene="rpsJ"
                     /locus_tag="ACG8M1_000517"
     CDS             30886..31194
                     /gene="rpsJ"
                     /locus_tag="ACG8M1_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFQ0421258.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31225..31854
                     /gene="rplC"
                     /locus_tag="ACG8M1_000518"
     CDS             31225..31854
                     /gene="rplC"
                     /locus_tag="ACG8M1_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFQ0421259.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            31882..32505
                     /gene="rplD"
                     /locus_tag="ACG8M1_000519"
     CDS             31882..32505
                     /gene="rplD"
                     /locus_tag="ACG8M1_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFQ0421260.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32505..32795
                     /gene="rplW"
                     /locus_tag="ACG8M1_000520"
     CDS             32505..32795
                     /gene="rplW"
                     /locus_tag="ACG8M1_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFQ0421261.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            32834..33667
                     /gene="rplB"
                     /locus_tag="ACG8M1_000521"
     CDS             32834..33667
                     /gene="rplB"
                     /locus_tag="ACG8M1_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFQ0421262.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            33710..33988
                     /gene="rpsS"
                     /locus_tag="ACG8M1_000522"
     CDS             33710..33988
                     /gene="rpsS"
                     /locus_tag="ACG8M1_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFQ0421263.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34011..34358
                     /gene="rplV"
                     /locus_tag="ACG8M1_000523"
     CDS             34011..34358
                     /gene="rplV"
                     /locus_tag="ACG8M1_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFQ0421264.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34372..35028
                     /gene="rpsC"
                     /locus_tag="ACG8M1_000524"
     CDS             34372..35028
                     /gene="rpsC"
                     /locus_tag="ACG8M1_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFQ0421265.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35031..35465
                     /gene="rplP"
                     /locus_tag="ACG8M1_000525"
     CDS             35031..35465
                     /gene="rplP"
                     /locus_tag="ACG8M1_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFQ0421266.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35455..35643
                     /gene="rpmC"
                     /locus_tag="ACG8M1_000526"
     CDS             35455..35643
                     /gene="rpmC"
                     /locus_tag="ACG8M1_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFQ0421267.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            35668..35934
                     /gene="rpsQ"
                     /locus_tag="ACG8M1_000527"
     CDS             35668..35934
                     /gene="rpsQ"
                     /locus_tag="ACG8M1_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFQ0421268.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            35992..36360
                     /gene="rplN"
                     /locus_tag="ACG8M1_000528"
     CDS             35992..36360
                     /gene="rplN"
                     /locus_tag="ACG8M1_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFQ0421269.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36397..36705
                     /gene="rplX"
                     /locus_tag="ACG8M1_000529"
     CDS             36397..36705
                     /gene="rplX"
                     /locus_tag="ACG8M1_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFQ0421270.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            36733..37272
                     /gene="rplE"
                     /locus_tag="ACG8M1_000530"
     CDS             36733..37272
                     /gene="rplE"
                     /locus_tag="ACG8M1_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFQ0421271.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37291..37476
                     /locus_tag="ACG8M1_000531"
     CDS             37291..37476
                     /locus_tag="ACG8M1_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFQ0421272.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37512..37910
                     /gene="rpsH"
                     /locus_tag="ACG8M1_000532"
     CDS             37512..37910
                     /gene="rpsH"
                     /locus_tag="ACG8M1_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFQ0421273.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            37942..38478
                     /gene="rplF"
                     /locus_tag="ACG8M1_000533"
     CDS             37942..38478
                     /gene="rplF"
                     /locus_tag="ACG8M1_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFQ0421274.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            38639..38995
                     /gene="rplR"
                     /locus_tag="ACG8M1_000534"
     CDS             38639..38995
                     /gene="rplR"
                     /locus_tag="ACG8M1_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFQ0421275.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39016..39516
                     /gene="rpsE"
                     /locus_tag="ACG8M1_000535"
     CDS             39016..39516
                     /gene="rpsE"
                     /locus_tag="ACG8M1_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFQ0421276.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39531..39710
                     /gene="rpmD"
                     /locus_tag="ACG8M1_000536"
     CDS             39531..39710
                     /gene="rpmD"
                     /locus_tag="ACG8M1_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFQ0421277.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            39754..40194
                     /gene="rplO"
                     /locus_tag="ACG8M1_000537"
     CDS             39754..40194
                     /gene="rplO"
                     /locus_tag="ACG8M1_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFQ0421278.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40194..41489
                     /gene="secY"
                     /locus_tag="ACG8M1_000538"
     CDS             40194..41489
                     /gene="secY"
                     /locus_tag="ACG8M1_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFQ0421279.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41551..42198
                     /locus_tag="ACG8M1_000539"
     CDS             41551..42198
                     /locus_tag="ACG8M1_000539"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFQ0421280.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42389..42607
                     /gene="infA"
                     /locus_tag="ACG8M1_000540"
     CDS             42389..42607
                     /gene="infA"
                     /locus_tag="ACG8M1_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFQ0421281.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            42640..42756
                     /gene="rpmJ"
                     /locus_tag="ACG8M1_000541"
     CDS             42640..42756
                     /gene="rpmJ"
                     /locus_tag="ACG8M1_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFQ0421282.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            42774..43139
                     /gene="rpsM"
                     /locus_tag="ACG8M1_000542"
     CDS             42774..43139
                     /gene="rpsM"
                     /locus_tag="ACG8M1_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFQ0421283.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43167..43556
                     /gene="rpsK"
                     /locus_tag="ACG8M1_000543"
     CDS             43167..43556
                     /gene="rpsK"
                     /locus_tag="ACG8M1_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFQ0421284.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43636..44574
                     /locus_tag="ACG8M1_000544"
     CDS             43636..44574
                     /locus_tag="ACG8M1_000544"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFQ0421285.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            44602..44982
                     /gene="rplQ"
                     /locus_tag="ACG8M1_000545"
     CDS             44602..44982
                     /gene="rplQ"
                     /locus_tag="ACG8M1_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFQ0421286.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45254..46093
                     /locus_tag="ACG8M1_000546"
     CDS             45254..46093
                     /locus_tag="ACG8M1_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0421287.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46069..46938
                     /locus_tag="ACG8M1_000547"
     CDS             46069..46938
                     /locus_tag="ACG8M1_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0421288.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            46928..47725
                     /locus_tag="ACG8M1_000548"
     CDS             46928..47725
                     /locus_tag="ACG8M1_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFQ0421289.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            47928..48674
                     /gene="truA"
                     /locus_tag="ACG8M1_000549"
     CDS             47928..48674
                     /gene="truA"
                     /locus_tag="ACG8M1_000549"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFQ0421290.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49129..51798)
                     /locus_tag="ACG8M1_000550"
     CDS             complement(49129..51798)
                     /locus_tag="ACG8M1_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFQ0421291.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52036..52224)
                     /gene="rpmB"
                     /locus_tag="ACG8M1_000551"
     CDS             complement(52036..52224)
                     /gene="rpmB"
                     /locus_tag="ACG8M1_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFQ0421292.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            52494..52856
                     /locus_tag="ACG8M1_000552"
     CDS             52494..52856
                     /locus_tag="ACG8M1_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0421293.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            52908..54590
                     /locus_tag="ACG8M1_000553"
     CDS             52908..54590
                     /locus_tag="ACG8M1_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFQ0421294.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            54707..56743
                     /gene="recG"
                     /locus_tag="ACG8M1_000554"
     CDS             54707..56743
                     /gene="recG"
                     /locus_tag="ACG8M1_000554"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFQ0421295.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            56792..57793
                     /gene="plsX"
                     /locus_tag="ACG8M1_000555"
     CDS             56792..57793
                     /gene="plsX"
                     /locus_tag="ACG8M1_000555"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFQ0421296.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            57915..58157
                     /gene="acpP"
                     /locus_tag="ACG8M1_000556"
     CDS             57915..58157
                     /gene="acpP"
                     /locus_tag="ACG8M1_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFQ0421297.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            58425..59429
                     /locus_tag="ACG8M1_000557"
     CDS             58425..59429
                     /locus_tag="ACG8M1_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421298.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            59430..60374
                     /locus_tag="ACG8M1_000558"
     CDS             59430..60374
                     /locus_tag="ACG8M1_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421299.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            60374..61336
                     /gene="opp4B"
                     /locus_tag="ACG8M1_000559"
     CDS             60374..61336
                     /gene="opp4B"
                     /locus_tag="ACG8M1_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFQ0421300.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            61363..62277
                     /locus_tag="ACG8M1_000560"
     CDS             61363..62277
                     /locus_tag="ACG8M1_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421301.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            62303..64084
                     /locus_tag="ACG8M1_000561"
     CDS             62303..64084
                     /locus_tag="ACG8M1_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0421302.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            64432..65118
                     /gene="rnc"
                     /locus_tag="ACG8M1_000562"
     CDS             64432..65118
                     /gene="rnc"
                     /locus_tag="ACG8M1_000562"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFQ0421303.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65138..68719
                     /gene="smc"
                     /locus_tag="ACG8M1_000563"
     CDS             65138..68719
                     /gene="smc"
                     /locus_tag="ACG8M1_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFQ0421304.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            68728..69537
                     /locus_tag="ACG8M1_000564"
     CDS             68728..69537
                     /locus_tag="ACG8M1_000564"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0421305.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            69548..70546
                     /gene="ftsY"
                     /locus_tag="ACG8M1_000565"
     CDS             69548..70546
                     /gene="ftsY"
                     /locus_tag="ACG8M1_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFQ0421306.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            70733..73000
                     /gene="gshAB"
                     /locus_tag="ACG8M1_000566"
     CDS             70733..73000
                     /gene="gshAB"
                     /locus_tag="ACG8M1_000566"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFQ0421307.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
BASE COUNT        23639 a        13281 c        15972 g        20134 t
ORIGIN      
        1 tactgataat gaaatttctc ctggttggga aaacgaagtt ggttaccctg tagaagaatt
       61 ttttcaagat tactttgcgg agtatgccga taggataatg agagattacg taacagataa
      121 aactcaagaa gtcatcaatc aatcccagtc attaaatgaa ttatctgata aggcgaaaga
      181 agaagcagtt gccattattt cttcagggat tagtgactat attgatatga gtggtgaaat
      241 caattatggc gataaagaca aaattgtacg catgataaaa gcttttatca aaacttttga
      301 tgtgaaggca gatcttaagt ttaatgatac ttacctagta ggaaaattaa ttaatatcct
      361 tgggacagag aaagatacgg aaacgtttat ttcctctttg tctatgttgt ttacagataa
      421 gcatttttca actcagcttg gtggagagga actagtggaa atcttttaac cattacgccc
      481 agcattaata aaagtatatc aaaaaagtac tcctgatgat ttttaagatt ggtttgagaa
      541 ataatgtgaa aacactattt ttaatgttaa ttatagatag agatgaacgc gtcatatggt
      601 taaaagaatg aaaaagtcaa agatacactg ctatatttca ctaaggatat agcagtgtat
      661 ctttcatgtc gtttcactgg cagtttttta taaaaggagg tgtgcatttc agttgctttt
      721 ctttggtagt tagttgaatc gtttaagaat taacggatgt ggcagacagg tgctctgtcc
      781 aaaaaccagt aaaatctttg atggttccat ctttatttag ctgtgcctgt tcaaatactg
      841 ttttgttttt accgaatgga tcaattgcaa taattgttcc gatccccgca cgtttggcag
      901 caagtaatcc tgagtaagca tcttcgataa caagacaatc agccggagct aagctcagtt
      961 tgtctgccgc tttaagaaaa atatccggtt gcggtttccc agggaaagag ccgtcgtcat
     1021 agacaatctt gtcccagtca aaccagcggg ctaaatcgaa aatatcaaaa taaaaagcaa
     1081 cattctcttt gacagtagcc gtggcaatcg ttaatggaat ctgttggtca gtcagctggt
     1141 caagagtcgc ttcaagccct tttgtcaact gaagctcgtt ttcattttgc aagcaaagca
     1201 tacgataata gctttctttt tcttctgaca atacggcgat ctcagaggcg gtcaaatgct
     1261 ctgaaatgaa atgtttcaaa atctccgtat tcgtccgacc atgaatattt tttaaaatat
     1321 cctcgtctga taaaccatct tttgtatgat catgtatcat atgcagccaa gcagcttcat
     1381 gcagatgaga gtccaaaaac attgttccgt tgaaatcaaa tataatccct ttcatagtta
     1441 cgctcctata gtggtatttt cggttgaatc agcaatttgc agatcgacat attgtgcata
     1501 gtgctcttga acctcccgcg agatctggcg atccgtaatg agcagatcga aatcatgcaa
     1561 attataaaac acataaaaat catctcgatt gaatttttta ttatcaacga gtagatattt
     1621 cttacgggaa ttatttagag cgatctgctg tgcttctcct tcttcggtac tgtaagtaga
     1681 gatcgcttcg ttgtgaacgc catttgaact gataaatgct tttgtaaact ttagtcttct
     1741 taaattgtcg ttggtgatcg gtccgacaaa tgcgccggta tttttccgga aatcaccgcc
     1801 aatcagtaga atttctggtc catctgcttg agcaagaata tcaaaaactg gataattatt
     1861 tgtaatgatc cgaattttct tgttcagtaa atgcgtcgcc aatagttcga ttgttgtacc
     1921 tggtcctaag aaaatcgttt ctccctcgtg aatcaaggag gctgctgtgg cagcaatttc
     1981 ttttttttct tgaatctgca gagtggcttt ttcagtgtga gaaagttctt gatctaaagt
     2041 gtaggaaaga ctttgagccc ctccatggac acgcagcagc ttgcccgatt tttctaattc
     2101 atctaaatct ctgcgaacgg tcatatcaga aacatctaat tgattgatga tttcattaac
     2161 ggtaaggatt ccttttttat tgaccatttc tacgatagta agcaatcttt cttttttcaa
     2221 cattgtcttc acctctaatt taaggataat ctatcatata aacggacaac agtcaatcta
     2281 attcgaacaa aagtaaacat ttagggtggt ttttatgttt gttacaatag attttattgc
     2341 tgttttctgg tttttatgat tatttgtgtt tgtttttgtt gacaaatgtt ttggatgcgt
     2401 ttacaatgca atcagttaga aagagcgaaa actgattata gatttgagga gagatgtaca
     2461 tgcttaaatt accagaagat tttatttttg gcggagccac agcagcctat caggttgaag
     2521 gagccactaa ggaaggtggc aaaggcgctg ttgcttggga tgacttttta gaggaacaag
     2581 ggcgattcag tcccgatccg gcaagtgatt tttatcatca atatgcaaag gacattgaat
     2641 tgtgtgaacg ttttggtgta aatggtctaa gattatccat tgcttggagc cgcatttttc
     2701 ctgatggagc tgggaaacca aatccagaag gaatcgcttt ttatcatcgt gtgttcgaag
     2761 aatgtaagaa aagaaacgta acgccgtttg tgacgttgca tcattttgat acccctaaac
     2821 gtttgtttga ccatggagat tttttgaatc gagaaacaat agaagcattt gtttcctatg
     2881 ccattttttg ttttcatgaa ttcaaagaag tcaaggtgtg gagtaccttt aatgaaatct
     2941 atccagttgc aaccaatcaa tatttgttag gtgttttccc accaggaatc aaatatgatt
     3001 ttacaaagat cgtcgcctgt cttcataata tgatggttgc tcatgcccgt gtagtgaact
     3061 atttcaaaga aaacgaactt ccgggtgaaa ttggtgtagt tcactcatta gagacgaaat
     3121 atgcggcaac agacgcgccg gaagataagc atgctgcctt tttagacgat gcattgtcga
     3181 tccgtttctt attagatgct acctatttag gctattattc aactgaaacc ttgactgctc
     3241 ttgatgagat atgtgaagca aatcaggcca gctatcattt tcctgaagaa gatttcgttg
     3301 aattgaaaaa agcatccacg cgtaatgact acttagggat caatcactac caatgccatt
     3361 ttgtcaaagc ttacgatgga gaaaatgcaa tccatcataa cggtacgggt gaaaaaggga
     3421 cctctgttta taaagtgaag ggaatcggag aacgtattta taaagaagga attcctcgaa
     3481 ctgattggga ctggctgatt tatccagaag gtctatatga cttgttgctg cgaattaaaa
     3541 gcgattaccc acattacaac aaaatctata tcactgagaa cgggatgggg tataaagatc
     3601 agtttgaaga tggcattatt atggatcagc cgagaatcga ctatttgaga gtctatttgg
     3661 aatccttaag caaggcgata acagccgggg taaatgtgaa ggggtatttt ttgtggtcgc
     3721 ttatggatct tttctcatgg acaaatgggt ataacaaaag gtatggcttg ttttatgttg
     3781 attttgaaac ccagaagcgt tacccaaaag aatcagctta ctggtacaag ttggtcagtg
     3841 aaaccaaaac gattatttaa taagtgataa tggaggaaga aaagatgaat aaagaggaat
     3901 tacaaatgct tggttttgag atcgttgcat attcaggcga cgctcgcagt acattattga
     3961 aattattgaa agaagtaaga caaggaaact ttgaacatgt tgattcggcg ttgaaagaag
     4021 ccgacgaaaa tttaaccctt gcacataatt cgcaaacaaa aattttagcg gaagaagcat
     4081 ctgggaaaga gatggagatg ggattcattt ttatccatgg gcaggatcat ttaatgacca
     4141 ctttattgct gagagatctg attcaagact ttattgtact gtacagacag aatcaaggat
     4201 aggagaagaa cgctatggat ggaatcatta aacaaatcga aaaagggaaa gcattttttg
     4261 aaaaaatctc acgtaatagt tatttaggag ccgttcgtga cggattttta acagcgatgc
     4321 cagctatttt attttcaagc attttcattt tgattgctgc ggttcctgag atttttggtt
     4381 accaatggcc tgaatctgtc tccacatggc tatggaaagt ctataattat tcgatgggtg
     4441 ttgtagggtt actcgtttca gcaaccactg ctcgctgctt ggctgattcg atgaatcgtc
     4501 gcttaccgaa aaacaaagta atcaacacca cctctgtgat gctggcctct gtggtaagtt
     4561 tcctgttgtt aagcgtctct ccgattgaag gtggattttc aacggaatat atggggacaa
     4621 agggactact ggcttccttt gtcgctgcat ttttaacagt taatttatat aagttttgtg
     4681 tgctgaaaga tattaccatt aaaatgccta aagaagttcc tggaacgatt tcgcaaacct
     4741 tccgagatat ttttcctttc tctttttcag tatttgcggc cgttttaatt gatttaggca
     4801 ttcgacaaat cttccaaatc tcatttgcag aagcaatcat tacggtgctg cagccgctat
     4861 ttacagcagc tgacgggtac ttaggaatcg ctattatctg gggagcgatg gcgctgtttt
     4921 ggtttgtcgg tgttcatgga ccgtcgatcg tggagccggc aattgcggca attatctatg
     4981 ccaatgtgga aaccaatctg caattgttca attccggtga acaagcttct aaagtactga
     5041 cggtgggttt agggaatttt gtaggaacta tgggaggaac tggggcaaca ttggttgttc
     5101 cttttatctt cctactcttt gctaagtcta agcagttgaa ggcagttggg aaagcttcct
     5161 ttattccagt aagtttcgct gtcaacgaac cattgctatt tgcggcaccc atgattttga
     5221 acccttattt ttttattcca tttttgttaa cacctgttgt aaacgtttgc ctgttcaagt
     5281 tttttgtcga tgtattgggc atgaacagct ttatgtacgt tttgccttgg gcaactccag
     5341 caccgatcgg tttggttcta ggaacgggca tgggtatctt agcttttgtt ctagcagcgg
     5401 ttctaatcgt cgttgacttc ctgatctatc taccattttg caaagcatac gatgctgtct
     5461 tagtagagaa agaagcacaa aaagcagagg tgatcgcaac cgaggaaggt gcttctgccg
     5521 atgtacgtga ggaagtacct gtggcagcga gtcaagttat cagcgatgca aataaagaaa
     5581 tcaatgtgtt ggtactttgt gctggcgcag ggacaagtgc gatgttagct aatgctttaa
     5641 aaaaaggtgc atctgaatcg aaagcaccga tcagtgcaat ggcgggtgct tatggttctc
     5701 attacgaaat gctgcaggat tttgatatgg tggtcttagc accgcaagtc aattcttact
     5761 atgatgatat caaagaagac accgatcgct taggaatcaa gctggttgcg acaaaaggag
     5821 cagaatatat cggattaacg agagatcctg aaaaagctgt tcagtttatt ctgaaccaat
     5881 ttcaataaag gaggagccat aatgaaaatg ggaatttggt tgcgtaaagc tgttttattt
     5941 gcagctgtgt taggggcttt gggggctgtt tcaaaaactg ttgaagcatc tgccagcgaa
     6001 tttattcgcg gagcagatat ttcgatcctg tcagatatgg aaaaatctgg tgcaaaatat
     6061 tatgaagacg atatttcaaa agatgcctta gagattttaa aaaataatgg tgtcaactat
     6121 gttcgactgc gtttgtggca ggatccttat aatagtaatg gagaaagtta tggagcaggg
     6181 acaaatgatc tggaaacgac gattgacctt gcaaaacgag caaaaaatct gggacttaag
     6241 gtgctgctgg attttcacta cagtgatttt tgggttgatc ctgggaaaca gaatcttcct
     6301 aaagcatggc aaggtctgac ctttgaagaa atgaatacgg cattgtacga ctatacaaag
     6361 aacgttctgt cggaaatgaa gcagctggac gtttatcctg atatggttca gatcggcaat
     6421 gaactgaata gcggaatgct ctggccttat ggcaagtctt ggggagaagg cgggggagaa
     6481 tttgatcgat tggctgcttt tttgaagtct ggtatccaag ctgttcgaga cactcaacct
     6541 aaaacaactc cagtaatgct ccacttagct gatggtggcg atacaggagc atttacttgg
     6601 tggtttgatg aaatcacgag tcgaggtgtg tcatttgatt taattggagt gtcgtattat
     6661 ccgtattggc acggttcaat gaatgaactt caaaccaata tgaatgcgat cagccaacgg
     6721 tatggtaaag aagtgatcgt agttgaaaca gcttatgggc atacaacagc gaatgccgat
     6781 actatgccaa atgcttttgg tgaagccgaa gcagctgcgg ggggatatga accaacaccg
     6841 acaggacaag cagagtattt gctggatctt gccgatcgga ttcaggcagt accgaataat
     6901 cgcggggcgg gcttcttcta ttgggaacct ctttggtaca acggaaatgt gagttgggca
     6961 acacaagcag gtatgaatta tctcagtgtt caatccacta tgggaaacga atgggacaac
     7021 caagcgatgt ttgattttgc tggaaacgcc ttgccaagct tgcgtgcgtt taaacaagca
     7081 ggggcgcaaa taaatctagt taaaaatgca agtttcgaaa gcgatggacc aacgaccagt
     7141 ccttccaatt ggcaaacctg gtttcaacaa ggaaccgcta agggtacgat caaaacggaa
     7201 gcgggcactt tttttgggga ctacaaacta actttttggc aggatcaagc atacgaggca
     7261 tcagcttatc aaaatgttag tggcataagc aaaggaactt acacattgag tgcctatgta
     7321 atgtctgggg gagagtttga tactaatcag ttatatatca aaaattatgg tggagcggaa
     7381 ctaaatactg cggttgttaa aacaagtgaa tggacaaaaa ttacaatcaa agacattcca
     7441 attacaacag gtgtttgtga aattggggtt tatagcaagg cttcaggaaa tgcttggacg
     7501 aacgttgatt ttgtttcatt ggtgaaacaa tagactgcgg atcgtttcga ttcaagatcg
     7561 gaggttccct tcagccacat cgttagcgta gaaggcagga atcgaacctg cacctcgcct
     7621 ttgccaaaaa taaccagaaa cgatttccag tcatttttac caaaacgagt aaagcaccag
     7681 acttcatcta cactttgtat tatgctaaag agagttcaac gatttcgtaa gaagcaatga
     7741 aaaaattgca aaaagttgtg cagataacat aaagtttgtt taagaaaggg taaccttaga
     7801 attccgtcgt gaatatgatt tgagcactta gatggataga aaaaagttct cggaaaacag
     7861 ttcgtttttc gagaacttct ttttatgata agaatgaaac aaattaactt atattatagt
     7921 ctcttttggt agggaaccat cttattttta atgaaaatca agcattttag ctattgaaga
     7981 atgttgattt atagggattc cccctccata ttatgttggc tctttattcc cactccactg
     8041 ttgctggtgg tttagaagtg atgtcataca cgatacggtt gacgtgggct acttcgttta
     8101 cgatacgtac agagattttt tgcaagactt cccatgggat acgggcaaag tcagcggtca
     8161 ttccgtcgat tgaagttaca gcacggatac cgactgtgta gtcgtaagta cgtccgtcac
     8221 ccataacacc gacagagcgg atccctggaa gaacagtgaa atattgccag atatcacggt
     8281 caagtccagc agctgcgatt tcttcacgca agatagcatc agattcgcgt acgatttcta
     8341 gcttgtcttc agtgatttcg ccaagaacac gaataccaag accaggacca gggaatggct
     8401 gacgccaaac gattgaatca ggcatgccta actgagtccc taattcacgg acttcgtctt
     8461 tgaataatgt gtttaatggt tcgatcaatt caaattgcat atcttctggc agtccaccta
     8521 cattatggtg agatttgatc gtctgtgctg tttctgtacc agattcgata acgtcagtat
     8581 acaacgttcc ttgtgctagg aaagagacgc cttcttcacc agcaagtttt gttgcttcgt
     8641 catcaaaaac atatacgaat tcattcccaa tgattttacg tttttgttct gggtcagata
     8701 cacctttcaa cttgtctaag aagcgatctc ttgcattgac tttgatgatg ttcaagccga
     8761 attttccgcc tagactttcc attacttgtt ccgcttcgcc tttgcgtagc agaccgtggt
     8821 caacaaagat agatgtcaat tggtcaccga tcgctttttg taaaagaacc ccaacgacac
     8881 tagaatcaac gccacctgaa agaccaagca agactttttt gtcaccaact tgttcacgga
     8941 ttttttctac ttgcatatcg ataaagttat ccattgtcca gttaccttca cagtgacaaa
     9001 catcaaaggc aaagtggcgc agcaattcga ttccgtattc ggaatgacgt acttctgcat
     9061 ggaattggat accataaaaa ttacgtgttg tgtcttggat agaagcaatc ggacaatctt
     9121 tgcttgttcc gactgtttca aagccttcag gaactttagt taccaagtca ccatggctca
     9181 tccatactgt ttgttgtttt ggtgtttctt taaacaagac agcttgatcg cttgttactt
     9241 ctaacaaggc tttcccatat tcgcggtttt tagcaggctc tacggaaccg ccaagtttgt
     9301 acgtgatcaa ttgcatacca tagcaaatcc ctaatacagg aatacctaaa ttgaagatct
     9361 caggatcgat cccaaatgca ttctcatcat atacactgtt tggtccgcca gaaagaatga
     9421 ttccctttgg attcatcgct tttacttctt ctgcagtaat gcggtggctc aataattcgg
     9481 aaaagactcc aagatcacga atacgtcttg tgatcaattg gttatactga ctaccgtagt
     9541 ctaatacgat aatcttttca acgttcgtca tatcggcaac gtttgtcaaa tttattaccc
     9601 ctatcccttt aaattttatc tcaaaatagt caaactattt taaaatgcta atattttcgc
     9661 atgaaaatcg aatcgatgat atgattttca gttttatgga gaattatatc ggctcttcct
     9721 cgtgtaggca agatatattc ctgtaaattt ttcaaattca catttttcca tacatctttt
     9781 gccattttaa aggcttcttc acgatctccg atagcaaaac gataataata attctctgga
     9841 ttttggaaag ccgtatccag taacgcacca aaacgatcca aataccattt ttcgatcagc
     9901 acgggatcgg catcgacata gacagaaaaa tcaaaaaagt cgctgacgta gatttgctga
     9961 ttcgcaggta attgaagcgt attgatcccc tcaacgatca agatatcagg ctgctggatc
    10021 aattcgtact tgtctggaat gatatcatac acatcatgtg agtaaacagg tacttttatc
    10081 tcttcctgac cagattttac acggttcaag aaatcgatca gcatctccat atcataactt
    10141 tcaggaaatc ctttacggtc catgattcca cgctctttta atatacgatt tggataaaga
    10201 aatccgtcag tcgtgatcag ctgaacgttt cttcgtttga aggtacgaga caaaatcgtc
    10261 tgcagcagtc tggctgttgt actttttcca acggctacac ttccggcgat cccgataata
    10321 aaaggcggta cttctacgta tttatgaaga aataaacctt tactcaagaa caaagattca
    10381 aattctttca tataaagata aatcagatga gcaagaggta catagatatc tcgaacatcc
    10441 tgcatggaaa tgcggtcatt caaacttttg atattatcta gttcatcttg tgtcaaaggt
    10501 gcttgcccat tacgataaaa ttctcgccat tcttctcttg ccacacggta gtagttcatt
    10561 ggatcattca tattagcctc ctgcgttctc ccatcaatgg aactatttta acacaaaata
    10621 aacgcaaacc ccaccactta agagagattg ccgatctttt tgtataatct ttataataga
    10681 aagaaacgga gtcttattct tgacttgcgc acggatacat aaaaggatag actgttgtca
    10741 tgaaagaaat gagaaggatg gaagacatga caaatcatta ctattctgaa cgcccagata
    10801 cggcgcacga ttttgaacaa tgggcttttg agttaaaagg cagaaccttt caatttgtaa
    10861 cagattctgg tgtattttca cgtgaaacag tggattatgg ttcacgtgtc ctgattgatg
    10921 ctttcgattg ggaagagtta cctgatgaag gaaagatctt agatgtggga tgcgggtatg
    10981 gaccgattgg gttagctttg gcatttgcga cacagcggtt tgttgaaatg gtcgacatta
    11041 atgaacgagc ggtaagtcta gcgcaaggaa acgcaaagcg taaccaaatc gaacatgttg
    11101 atatccatca atcgaatatc tatgaagcag ttcatgaaga aacctatgca gctatcgtaa
    11161 gcaatccgcc gatccgtgct ggaaaaaaag ttgtacatga aattttgaca ggcgcatatc
    11221 ctcggttgaa gaagggcggt acactgacaa ttgtgatcca gaagaaacaa ggagcgccga
    11281 gtgcgcaaaa gaaaatggaa gaaacatttg gtaatgcaga aatcgtcaca aaagataaag
    11341 gatattatat catcaaaagt gtgaaagaat aactagctga aaaatagtgg agcgacgaaa
    11401 gagtggaact gggcgtgcat gtacgggtac gtatcagttc tttttttgtt gagaagtttt
    11461 taaaaacaaa gaactatttt ttcttcaaaa agaaatagta ggaacagagt cgttgttttt
    11521 tacgataaaa taaataagat acagaacttg tatagaaggc tgccaagtcg gtagataaag
    11581 gaggttttta tcaaaaaaca tactttcctt ttttctctat tcttttcttg ggggttttgg
    11641 tacactgata gggaatttag atagaaggga gccaatagga tgaagctgac catcagagat
    11701 atcgcagaaa tggcaggcgt atcagtaaca actgtctcac agattttgaa taacaaagga
    11761 agcagattta gtgataagac aagaaaaaaa gtgttgtcga tcgtgaatga acatcattat
    11821 aagcccgatt atttcgcttc aaatgtgatc aatcgacatt caaagaccat cggaatgatc
    11881 gtccctgatg tcactgattt cttcttctcc aaactgatcg aaggtgtaga gagctatttg
    11941 aatcctttgg gctatgtgat catgttatgc aattctcgtc atagccaaga aaatgagatc
    12001 aagtatttac aagagctttc ccaccgctca gtggacggaa tcttgctggc cacaccaaat
    12061 attttacctg agaaatatgc attagacagc ggtttttatc aaaaaatgcc aatcatttta
    12121 atcgatcgcg gattgaatcg tcgggataac ggacggctta tcgtaaagga atatgagggc
    12181 gcctatcaag ctgtttcgct gtttattgaa aatggccata cgaagatcgg catgctgaag
    12241 gaaaccactg gatactatca attagaagaa cgtttcaacg gatatcgtca tgcgctgaaa
    12301 gatcatggcc tgccttttaa tgggaaattt gttgaacatg gagagttgac tgtccaaggt
    12361 ggatatactg catcaaaaaa attactcaaa cataaagata tcacggctat tttttgcggg
    12421 aatgatgcca tggcgatcgg atgctatcag gcgatcgatg aattgggcaa aaaaatccca
    12481 gaagatatct cagtcatagg attcgatgga ttaaagctgt cagaatacat gattccgcaa
    12541 ttgacgacag tgcagcagcc aagttttgat attggatttt atgctgcacg tttcctgatc
    12601 gatacgatcg aatttcctca aagaaaagtt ccgaacaaag tgttcgaaac aaaattaatt
    12661 attcgtgaga gcgtaaaagt attgacaaag ggctaactcg gcggtatatt gcttatgtaa
    12721 gcatttacaa aggctagtta gtgctttttt tatttttagt aaaccagttt actaaagtgg
    12781 tttacctttc ctaaaaataa tgtataatac cgaatgaaga caaggaggat caggcaatgc
    12841 gaatggtgga tctgattgaa aaaaagaggg atggaaacga gctgtcgaaa gaggaaatcg
    12901 agtacatcgt cacgaactat acgaatggaa agattccaga ttatcaagtc agtgcattat
    12961 tgatggcaat tttttatcaa gacatgacaa atgaagaaat cacgaactta acattggcga
    13021 ttgctaattc tggtgatgtc atcgatttga gttctcttga aggaataaag gtagataagc
    13081 attcgacagg tggcgttggt gacacgacca cattgatttt agccccccta gtagctagtg
    13141 tcggagtgac agtggctaaa atgtctggac gcggtctagg ttacacaggt ggtacactag
    13201 acaagctaga agcaattccc ggatttcaga tcgagctttc ggatgaagaa tttgtacgca
    13261 ttgttaatga aagtaaagta gcggtaattg gtcaatcagg aaacttggca ccggcggaca
    13321 aaaaattgta tgccttgcgt gacgtcacag cgaccgttga ttctcttccg ctgattgcca
    13381 gttcgattat gagtaaaaaa atcgcggcag gagcagatgc aatcgttttg gatgtgacca
    13441 ctggagacgg tgctttcatg aagaacatcg aagatgcaag acgtctggca aagaccatga
    13501 cgagcattgg gaaactggct aaccgagaaa cagtggcggt tatctcagat atgtcagaac
    13561 ctcttggcga agctatcgga aatagtctag aagttgtcga ggcaatcgaa acattacaag
    13621 gaaatggtcc agaagatcta gtagaaatgt gctacgcctt aggaagccaa atggttgttc
    13681 ttgctggcaa agctaagaca accgatgaag caagaacgtt gcttcaagaa gctctggaat
    13741 caggtaaagc gttagcaaaa ttcaaagaaa tgatccaaaa tcaaggggga gacccagcga
    13801 tcgtggaaca tccagaacga attttgactg cacgctacac aatggagctt cctgctaaac
    13861 aaagcggagt tgtgtcaaaa atcgtggcaa atgaattagg aattgctgca atgatgctag
    13921 gtgctgggcg taaaaccaaa gaagaagata ttgatcacgc tgttggattg aaactgcata
    13981 aaaaaattgg tgacactgtg acaaaaggtg agtcactatt gacgatctat agtaacgacg
    14041 aagaaatcac ttctgtcatt gaattattat ataaaaatat tgaaattggt gaatcggcaa
    14101 tgaagccaac gttgattcat gacatcatca cagaataaag gaaaaaagcg gactttaccg
    14161 ttttaaagaa aaggggaaaa gaaatggaac taaaccgaat gatcgaccat actattttga
    14221 aagcagacgc atctaaagaa gctgtgatgc aaattatcga agaagcaaaa aaataccatt
    14281 tttattctgt ctgcatcaat ccagcatggg ttgcgctagc gaaagaacaa ttacaaggtg
    14341 agccagtagc cgtatgtaca gtaatcgggt ttcctctagg agcaaacaca cccgagacaa
    14401 aagcatttga aacaacagat gccatcaata acggtgcaga tgaagtcgat atggtcatca
    14461 atatcggtgc tttgaaatca aaggatgatc aacaagtcca aaaagatatc gaagcagttg
    14521 ttgaagcagc aaaagatcgt gcgcttgtca aagttattat tgaaacatcg ttattagata
    14581 gagaagaaat catccgagct tgcgaaatag caaaagctgc aggcgctgat tttgtcaaaa
    14641 catcaactgg tttctcaaca ggcggagcaa aggtagagga tgtccgtttg atgcgtgaaa
    14701 ctgtaggacc agaaatgggt gtcaaagctt ccggcggtat ccataacgaa gaagaagcaa
    14761 tggcaatgat cgaagctggt gctacaagaa tcggaacaag cgcaggagta gcaatcgtat
    14821 ctggttcaac tggtgaaggc tattaatttt ttcaaaggag aagctcatgg cagaactcaa
    14881 acaagaatgg atcaacacag ctattgaagc gttagataaa gcctatgttc cttattccca
    14941 ttttccggta ggcgcttgtc tcgtaacgga atcaggcaag atttatcaag gcatcaacat
    15001 tgagaatgca tcatttggat taacgaattg tgccgagcgc acagcttttt tcaaagcagt
    15061 atctgaagga gaaaaaacat ttacgcatct agtcgtagcg gggcacaccc ccgatcctat
    15121 ctctccttgt ggtgcatgtc gacaagtaat ggcagaattc tgttcccctg atatgccggt
    15181 tacgctagta ggagacaatg gtgtgacgaa ggcaacgacc gttcgtgcac tgctgcctta
    15241 tgcatttact gaaaaagatc tataactcat gttcattcag tcagctgact gttgaaaaat
    15301 aaaacaatta ttttaggagg ctttacagaa atgaaaaaag caaaattatt tggtttaggt
    15361 gctgtcgcac tagcagcagg gttattttta ggtgcatgcg gcaacaacgg ctctactgat
    15421 tcatccggtg gcaaaagctc atcagacaca acaactgcag cattgatcac agacacaggt
    15481 ggtgtagacg accgttcatt caaccagtca gcttgggaag gactagaaaa atgggggaaa
    15541 gatcaaggac tttcacgagg aaatgatggc ttccaatatt tccaatcttc aaatgaatca
    15601 gattacatcc caaatattga ccaagcattg aatgctggat tcaaaacgat ttttggtatt
    15661 ggttataaac taaaaccagc gatccaagaa caagcaacaa acaatacagg tacgaacttt
    15721 gttattatcg atgatgtcat cgatggatta gataacgttg tatctgcaac tttcaaagac
    15781 aacgaagctt cttatcttgc aggtgttgca gcagcttata cgactgaaac aaacgtagtc
    15841 ggctttatcg gcggtgtaaa aggtgaagta atcgatcgtt ttgatgctgg attcaaagcc
    15901 ggtgttgatg caggtgcgaa agaattagga aaagaaatca aagtattgaa tcaatatgct
    15961 ggtgacttct ctgctccaga taaaggacgt tcaattgctc aaggtatgta tgcacaaaac
    16021 gcagatatca tcttccatgc ttcaggcggt acaggtaacg gtgtattcca agaagcaaaa
    16081 tcattgaacg aatcaggcga caaaaaagtt tgggttatcg gtgttgaccg cgaccaatca
    16141 gacgaaggcg aatacacatt aaacggcgaa aagaaaaact tcacattgac atctacactg
    16201 aaagcagttg gaacagtagt agaagatttg gcacaaaaat cagcggacgg taaattccct
    16261 ggcggcgaac acactgttta tggattgaaa gaagacggtg ttggtctaac agaaggacaa
    16321 ctttctgacg aagcgaaaaa agcagttgat gaagcaaaag aaaaaatcat ttcaggtgac
    16381 gtaaaagttc cagaaactcc tgaagaaaac taaaaccatt tctatagcct tgttagacac
    16441 atgtttgaca aggctatggt ttgattagaa caagaattgt tcatttatcc aagctgcctt
    16501 gtgacagttt ggataaggga acaactccct gaagtaatgt ttgtttcaaa agaagaacgc
    16561 tcactaagcg tgaatcttag tcaatcgttg ccctagatag aaatcgttag gatgtgaaaa
    16621 aaaggtggtt caagaaaata ttgtcataga aatgcagaat attaccaaag aatttggaac
    16681 attcaaggca aatgacaaca tcaatttaca agtaaaggca ggagaaattc atgcgttgct
    16741 tggagaaaac ggtgctggca aatctacatt gatgaacgtg ctttccggat tattagagcc
    16801 gacatcaggg aaaattttga tgcgtgggaa agaagtaaag atcacaagtc cgaccaaagc
    16861 caaccaatta gggattggga tggtccatca gcactttatg cttgttgatg cctttactgt
    16921 aacagaaaac atcgtgttgg gaagcgagcc tagtcgcgca gggatgcttg accataaaaa
    16981 agcacgaaaa gagatccaaa aagtttctga acagtatgga ttgtcagtca acccagatgc
    17041 ttacgttcgt gatatttcag ttggaatgga acaacgggta gaaattttaa aaacacttta
    17101 ccgaggagca gatgtactga tttttgatga gccgacagct gtattgaccc ctcaagaaat
    17161 tgatgaatta atcgtgatca tgaaggaatt agtcaaagaa ggcaagtcga tcattttgat
    17221 tacgcataag ttagatgaaa tcaaagcagt agctgaccgc tgtacagtta tccgccgtgg
    17281 aaaaggaatc ggtacagtca acgttaaaga cgtaacctca caacaattag ccgatatgat
    17341 ggttggaaga acggtttcat tcaaaacgat gaaaaaagaa gcgaagcctc aagaagtcgt
    17401 tttgtctatt gaaaatctag tggtgaaaga aaatcgtgga ttagaagccg tgaaaaactt
    17461 gaacttagag gttcgtgctg gcgaagtact tggtatcgct ggaatcgatg gaaacgggca
    17521 gtcggagttg atccaagctt tgactggttt gcgaaaggca gaaagcggac atatcaagct
    17581 aaaaggggaa gacatcacta ataaaaaacc ccgaaaaatc actgaacatg gtgtaggaca
    17641 cgtgccagaa gaccgtcata aatacgggtt agtcctagat atgacattat ctgaaaatat
    17701 cgcactacaa acctatcatc aaaaacctta cagtaaaaac ggcatgctga attattcagt
    17761 aatgaatgaa catgccagag aattgatcga agaatatgat gttcgaacaa cgaatgaact
    17821 tgttcccgca aaagctttat caggcggaaa tcagcaaaaa gcaattatcg ctcgtgaagt
    17881 cgaccgagat cctgatctgt tgattgttgc aaatccaact cgtggactgg atgtaggtgc
    17941 gatcgaattt attcataaac gtctgatcga acaaagggac aaatacaaag cagtgttact
    18001 gatcagtttc gaattagaag aaattttaaa tgtttcggat cgtattgctg ttatccatga
    18061 aggagaaatt gtcggtatcg ttgatccgaa agaaacatct gaaaatgaat taggtctatt
    18121 gatggcgggc tataccttag aagaagcacg aaaagagtta gaaaaggggg ctggcgcaca
    18181 tgaatgatcg cagcgaaaaa ttccgtaatt tattagtgcc tgtactttca gttgttttag
    18241 gattgatctt aggcgcgata ttgatggctg cttttggttt tcagcccatc caaggttatt
    18301 cttctatgct agatgcagcc cttggttcgc aaagagggat aggtgaaacg ttaaggcaag
    18361 caacgccgtt gatttttaca gcattaggtt tttctgtagc taactcagct gggtttttca
    18421 atattgggct ttctggacaa gcactttgcg ggtggatcgt cagtgtctgg gtggcacttg
    18481 cgtttccaga tctgccaaaa gttgttttgc ttccgttatg cgtgatctta ggtgccttag
    18541 ctggtgcgat ggcagcggct gttccaggtt tacttcgagc attttttgga acaagtgaag
    18601 tgatcgtaac aatcatgatg aactatatct tattatacgt aagcacattt gctttacatg
    18661 aagtgatgcc tgaaagctat cgctcaagtt tggactcttc caatatgatc agtcaaaatg
    18721 cctcactgcg gttaccatgg ttaacacaag cttttggcgg ctctcgcgta aactcaggat
    18781 tatttttagc aatcatcgcg cttattttcg tttggctgct gatgaagaaa acgactttag
    18841 gatttgaaat ccgttctgtt ggattgaatc cttttgcttc tgagtatgca ggaatgagta
    18901 gtaaacgtac gatcgttttg tcgatggtca tttctggcgc tttggcaggg cttggcggtg
    18961 tggttgaagg attaggaacg tatcaaaact tctttgttca aacgacttcg ctatctattg
    19021 gatttgacgg aatggctgtt tccttgcttg gttctggatc agcaatcggt attcttttat
    19081 cagcgatctt gttcagtatt ttgaagatcg gtggacttgg catgcagaca ggagcaggtg
    19141 ttccgtttga gatcgtcaat gtatcgattg ctttgattat cttctttgtc gggatcaact
    19201 tcctgattcg tttcgtcatg gctaaagtct tccaagggaa aaaacaagaa gagatcgttg
    19261 cgacaataga atcgaaacca acgaatcaaa accatgaagg gggcgaacta taatgtcgac
    19321 tatcgaatta attgccttga tccttacttc tacactggtt tattcaacac cgctaattct
    19381 aacgtcacta ggcggaactt tttctgaacg aagcgggatc gtaaacgtag ggctagaggg
    19441 aatcatggtc atgggtgctt ttagttccat cgttttcaac ttgacgatga gtccatcact
    19501 tggttctatg acaccatgga tcgctatttt agtgggtggc gtcgtaggta tcctattttc
    19561 tctgattcac gcagtagcaa cagtcagttt gcgtgctgac catattatca gcgggacagt
    19621 aattaatctg atggcacctg ctttaggtgt tttcttgatc aaagcatggt atggtaaagg
    19681 tcaaactgat aacatcacgc agaatctggg gtatttttct ttcccaggat tagcagatat
    19741 tccggtcatt ggaccaattt tctttaaaaa tacattctta cctgcttatt gtgctatttt
    19801 gattgctgtc ctagcttggg tgatcatctt caagacgaaa ttcggcttgc gcctccgttc
    19861 agttggtgaa aatcctcaag ctgccgacac attaggtatc aatgtatatg ctatgcgtta
    19921 ttcaggcgta ctgatttctg gcttgttagg cggtatgggc ggtgctgttt ttgctcagtc
    19981 gatttccggt aacttttcag ctggtacgat cgttggacaa gggttcatct ccatggctgc
    20041 tatgatcttt ggtaagtgga atcctttagg ggcaatgggt gcctcattgt tctttggttt
    20101 tgctcaaagc ttgagtatca ttggcgcaca attaccagtt atttcttcga ttccgccagt
    20161 attgctgcaa attgctccat atttgctgac aatcattgtg ctggttgttt tcttagggaa
    20221 agcttctggt ccaaaagcaa acgggaagaa ctatatcaaa tcaaaataat cttttagcga
    20281 ataaaaaggg tgggttacgg gaagtgtttt tcgtctcgcc ctttttgttt taaaggcaat
    20341 aaaaataaaa agaaagaagg aataatcatg tttaaacgcg tacatctgat cgtcatggat
    20401 tcagtaggaa ttggagaagc accagatgcc gataagttcg gtgatgttgg ttctgataca
    20461 ttaggacaca ttgcgaaaga agcaggattg aacgttccac atttagagca gcttggttta
    20521 ggaacgatcc gtcctcttga aggtgtggaa tcagtgaaag atcatcaagg ctatgcgacg
    20581 aaattagaag aagtttctgt agggaaagat acgatgacag gccactggga aatcatggga
    20641 ttgaatatca aaactccatt tcgtgtgttt cctaatggat tccctgatga tctgatcaaa
    20701 caaatcgaag aattttctgg ccgtaaagtc gtatgtaaca aaccttatag cggaacagct
    20761 gttattgacg attacggtga acaccaaatg aaaacaggcg atttaattgt atatacttct
    20821 gccgatcctg tccttcagat cgcggcacat gaagaaatca ttcctttaga agaattatat
    20881 cggatttgcc aattcgttcg tgatataaca aaagatgatc cgtatatgat tggccgaatc
    20941 attgcacgtc cgtacgtggg tgaaccagga gacttcacac gaacaagcaa tcgccatgat
    21001 tatgcgttga atccattcgg acacacagtc cttgattctt tgaaagaagc aggaaaggac
    21061 gtgattgctg ttggaaagat caacgatatt ttcaacggac aaggaatcac tgaatctgtc
    21121 cgcacgaaaa gcaatatgga tggcgttgac cagctgctga aagttatgaa aaacgatttt
    21181 tcaggaatca gctttaccaa tttagtagat tttgatgcat tatacggtca tcgtcgggat
    21241 gtagtcggct atgcgcatgc gattgaagaa tttgacttac gaattccaga attgcttgaa
    21301 gcgatggaag aagacgactt gctaatgatt acagccgatc acggaaacga tccgacgttt
    21361 actggtaccg atcatacgcg agaatatgta ccgttattgg tttacagtaa aaaaatgaaa
    21421 gaacaagggg cattgcctca aggatattat tcagatattt cagcaacgat tgctgagaac
    21481 tttagtgttt cttcgactga aaatggcgaa agcttcttga aattattaaa ataatctttt
    21541 taaataggag aaagcaaatg accaagttaa gcgagatgtt acaagaaacg acccagttta
    21601 tccttgataa aggagtaaaa gaaattgatt ttggtttgat tctaggttca ggattaggtg
    21661 aattagcaga tgaaatcgaa gatgctgtaa tgatttctta tgatgagatc ccgttctttc
    21721 ctgtttcgac agtagttggg catgcaggaa agctagttta tgggtctctg gcaggcaaga
    21781 aagtgttagc catgcaaggg agattccact actatgaagg tcattccatg caaacagtga
    21841 cctatccagt acgtgtgatg gccggactag gggcccattc agtcattgtg actaatgcat
    21901 gtggtggtgt caacgaatca tttgtaccag gagatttgat gctgattacc gatcatatca
    21961 attttactgg tgaaaatcct ttgatcggtc cgaatgaaga tgcaatgggc cctagatttc
    22021 cagatatgag tcaagcttat acgcctgact atcaagcaac agcaaaagca gcagcagaaa
    22081 aactaggttt ggatcttaaa gaaggcgtat atatgggcta ttctggacca acttatgaaa
    22141 cgcctgcgga gatccgaatg tctcggacaa taggagccga tgcagtaggg atgtcgactg
    22201 ttccagaagt catcgtagca gctcacagcg gattaaaagt gttaggaatc tcttgtatta
    22261 ccaacttagc agcaggtatg caagcgaatc tgagccatga agaagttgta gaaacaactc
    22321 agagagtcaa acaatctttt aaagcattgg ttaaagaaac attgacatta ttgtaatagg
    22381 aggaacaata aaatgagtgt gcatattgaa gcgaaagaag gcgagatcgc cgataagatt
    22441 ttacttccgg gagatccttt gcgagctaaa tatattgcgg agactttttt ggaagatcca
    22501 gtttgttaca atcaggtacg cggtatgtta ggctttaccg gcaaatataa aggagaacgt
    22561 atttctgttc aaggaacagg aatgggaatg ccatcagcca ccatctatgc ccatgaattg
    22621 atccagtcgt atggtgtaaa gaaattgatt cgagtaggta catgcggtgc attgtcaaaa
    22681 gacgtccatg ttcgtgattt agtactagca caaggtgcag cgaccagttc ttcgatgatc
    22741 gaaaaaaatt tccaagcctt tcattttcct ccaatcagtg atttcaatct attactgaaa
    22801 gcatatgaga tagctaaaga aaagggctat acggttcatg taggaaatgt tctttcggaa
    22861 gattctttct acaaagatga tttgacagag acgttccaat tagctgaact tggcgtttta
    22921 ggagtggaaa tggaagcagc ggctctttat tacttaggcg cgaaatacca tgtgcagaca
    22981 ttaagtttga tgaccgttag cgaccatttg atcaccggtg aagaaacaac agctgcagaa
    23041 cgtcaatcta cgttcaatga aatgatcgaa gtaggattgg aaacagcgat agcagaataa
    23101 gaaggaaatg aaaaagctgc cctgcattaa gtaataagaa catccaagca aaaatagctc
    23161 ctcatgtttt tgacttggct ggacttatta ttgcaaatgt aagcttttga acaccgttta
    23221 ccaagaggtt gtgaatctgc cgtttaactc tgagtcacaa ggaacaattt caaaaaacag
    23281 cttttcatgt ttgatgaata ttgtgacttg tgaccgagaa gttggcagga gaaaaccgtt
    23341 tatacgaaaa aagggactgt gacaaatcgt gtcacagtcc cttttttata gtgtttttta
    23401 taggtagtat tttttagcaa ctgttaagtc atcatttaat tcataaacaa gtggttgacc
    23461 tgttggaatt tcaagatcca tgatgtcttc gtcagagata ccttcgatat gtttagctag
    23521 ggcgcgtaat gagttaccat gtgcagctac taaaacagtt ttgttgtcta gtaatgctgg
    23581 agcaatttca tcttgccaga atggcaaagc gcgttctaat gtcactttca agttttctcc
    23641 accaggaata tcgcgtttgt ctaacattgc gtaacgacgg tcatttgctg cagaaccttc
    23701 gtcagtttct tccattaatg gaggaagagt atcgtaagaa cgacgccaga tgtgcacttg
    23761 ttcgtcgccg tatttttcag ctgtttcttt tttgttcaaa ccttgtaatt taccatagtg
    23821 acgttcgttt aagcgccatg atttgatttg tggtacccaa agttgatctg aatattctaa
    23881 gatcaagtta catgttttga ttgcacgagt taaaacagaa gtgtaagcaa catcaaattc
    23941 gattccagct tctttgattt tgcgtccgcc ttcttttgct tcttcgattc cttctggtgc
    24001 tagatttaca tcagcccaac cagtaaattg gttcaatgca ttccattcac taagaccgtg
    24061 acgagaaaaa actaattttg gcatgtttag ctctcctttt aagataggtt tatatttctg
    24121 aaattttcag ttctgtttta ttgtacaatt ttttggaaga gatttccatc gaaaaattag
    24181 ataagattct atgagaaaac aagtagagaa tataaaaaaa cgaacagtgc ccacgcaact
    24241 gttcgttttt aggtattaga tgcataattg ctcgatttct ttttcaggta aattgatata
    24301 tttataacat gttccaactg aaacaccgca ttttgaagaa ataaattgga tcgtttcttt
    24361 tttttcataa tagagacgtc ggattttttt gatcgttttt gcatcgattt ttggtcttcc
    24421 gccgattttt ccttttttac gagcttcatc taatccaact aatgtacgtt ctttgatcaa
    24481 tgcgcactcc atgtttgcta ggttttccat taattggaaa tagatttttc ccatttcgcg
    24541 cgtatcgatt ccttcatcaa gactaatcaa gtgcagcccg cgatctttga ataattgcgt
    24601 gagttctgtt aattgccgcg tagatttgcc taatcgatga agttggcaaa tgactagtgc
    24661 atcgccttgt tgcatgtcag cgatcactga ctccaaatga acagcagtag aatcattttg
    24721 ttccacttca tatgtctcat ggaaaatttc ttgacaacca aagtcagata attgatcaac
    24781 ctgagttgtt aaatcaacgt catttatggt tgtgcgtgca taaccaataa ttttcatggt
    24841 gattcctttc tagcagtgat tttctaactg gatataacag taaaaatgta gcataaagta
    24901 cgtcaaaaag atagtttttt cgcaaatttt ccgctgtctt tttttattgg atgatcaagc
    24961 agtttttctt tatttacgac ggattgcgtc aagaatctca acgccttttt ctgagccgac
    25021 aactacttta gaaaccatgt ttaggaaaag cccatgttct actaccccaa caagttcatc
    25081 taaataggta gctaagcttt ctggctgttc gatgacttct agatgcagat caatgatgta
    25141 atgaccacca tctgtggtta agacttctcc gttttcgtct gtacgcaaga cgggttggaa
    25201 tcttttttct tcaaaaatat gaagtagctg ttgggagcca taagggatca cttcaactgg
    25261 gagtgggaac ttcccaagtt tatcgactaa tttagaagaa tcaacgatcc aaatcgtttc
    25321 ttttgagtac gtagcgacta ttttctcgaa aagcaaagca gcgccgccgc ctttgatccc
    25381 ttgaaaatca gcactgattt catcagcacc gtctattgtc aaatcgacta cggggacttc
    25441 atcaatactc tttaacggta ttcctaattt ttccgcttgt tcttttgtcg catttgaagt
    25501 agtaactcct gtgatacgta aaccttcttc acgcatacgg cgaccaatct cttctaccat
    25561 ataataggcg gttgaaccgg tcccgagacc tacgatcatc ccgtccttta cgaatttcgc
    25621 ggcttcaatg ccagctaatt gttttaaatt catctttgcg tccacctttt tttagtttga
    25681 gcatcgtgct ttcctcacta ttttagcgtg atttacggta aaaagatacc attctttttt
    25741 attccaataa agctttttca aaaaaaattg catctcttgt tgacatgttt tttcattcgt
    25801 gatattctaa caaaggtgct ttatctacag gtttctgtga agaaacgtgc tgactgttta
    25861 tcaaagcata tttgataagg atgcagacat tgcatttatt ttttatcaca aaaaaagaac
    25921 cacctggatg tgtggaacta gacgcaaatc gtgggaagga ggaaacaagg aatgcctaca
    25981 attaaccaat tagtacgtaa acctcgtaaa tcaaaggtgg aaaaatctaa ttcacctgct
    26041 ttgaacaaag gatataacag ctttaagaaa actcaaacta acgtaaactc acctcaaaaa
    26101 cgtggggtag caactcgtgt gggtacaatg acacctaaaa aaccgaactc agctttacgt
    26161 aaatatgcac gtgttcgttt gtcaaactta attgaagtta ctgcttatat cccagggatt
    26221 ggtcataact tacaagaaca cagtgttgta ttattacgcg gtggtcgtgt aaaagactta
    26281 ccaggggtac gttaccatat cgttcgcggt gctttagata ctgctggtgt taacgaccgt
    26341 aaacaaagcc gttctaaata cggaactaaa aaacctaaag cttaatttta attattaaac
    26401 aaatgaaact tgcttctact atatagaagt aattactatg aacaatattt cggaaggagg
    26461 agttacggat gccacgtaaa ggtcctgttg caaaacgtga tgttttacca gatcctattt
    26521 ataactcaaa attagtaact cgcttgatca accgtgtaat ggttgacgga aaacgcggga
    26581 ttgcagctaa cattatctat aatgcctttg acttgatcaa agaatctaca ggtaacgatc
    26641 cattagaagt gtttgaacaa gcaatgaaaa acgttcaacc tgttcttgaa gttaaagcac
    26701 gtcgtgttgg gggttcaaac taccaagtac cagttgaagt tcgccctgaa cgccgcgtta
    26761 ctctaggtct tcgttgggta gtaaactacg ctcgcttgcg cggtgaacac acaatggaag
    26821 aacgcttagc aaaagaaatc atggatgctg caaacaacac aggtgcttct gttaaaaaac
    26881 gtgaagacac tcataaaatg gctgatgcca accgtgcgtt tgctcactat cgctggtaag
    26941 attctctctg tttggtcggc ttttataagt cgacctcaga tagtgtcctt atttttagca
    27001 actagatagt aaagagagga gaaacaagga gaatgaccag agaattttct ttacaaaaca
    27061 ctcgtaatat cggtatcatg gcccacatcg atgctggtaa aacgactgct actgaacgta
    27121 tcttgtacta tactggtaaa atccataaaa ttggtgaaac tcatgaagga gcttcacaaa
    27181 tggactggat ggaacaagaa caagaacgtg gtattacgat cacttctgct gctactacag
    27241 cacaatggaa gggtcaccga atcaacatca tcgacacacc aggacacgta gacttcacag
    27301 ttgaagttga acgttcattg cgtgtacttg atggtgctgt aactgttctt gatgcacaat
    27361 caggtgttga acctcaaact gaaacagttt ggcgtcaagc aacaacttat ggtgtacctc
    27421 gtatcgtatt tgcaaacaaa atggacaaga tcggtgctga cttcttatat tcagtatcaa
    27481 ctttacatga ccgtttgcaa gcaaacgctc acccaatcca attaccaatt ggtgcggaag
    27541 acgacttcac aggaattatc gaccttgtaa caatgaaggc tgaaatgtat acaaacgatc
    27601 ttggaacaga gatcgaagaa acagaaattc ctgaagaata ccgcgaatta gctgaagaat
    27661 ggcgcgaaaa attggttgaa gctgtagctg aaactgatga agaacttact ttgaaatact
    27721 tagaaggtga agaaatcact gaagctgagt taaaagaagg tatccgccgc gcaacagtta
    27781 acgtagaatt ctacccagta ctatgtggtt cagcatttaa gaacaaaggg gttcaattac
    27841 tattggacgc tgttcttgat tacttgccat caccgttaga tatcccagct atcaaaggga
    27901 ttgaccctaa aactgatgaa gaagtagaac gtcctgcaga cgacagcgct cctttctcag
    27961 ctttagcatt taaagttatg actgacccat tcgtaggtcg tttaactttc ttccgtgtgt
    28021 actctggtgt tttacaatca ggttcatacg tacaaaacgc aacaaaaggc aaacgtgaac
    28081 gtgttggtcg tatcctacag atgcatgcca actctcgttc agaaatctct gaagtttacg
    28141 ctggagatat cgctgctgct gttggtttga aagacacaac tactggggac acactatgtg
    28201 atgaaaagag tctagttatt cttgaatcca tggaattccc agaaccagtt atccaagtcg
    28261 ctattgaacc taaatcaaaa gctgaccaag ataaaatggg tgtggcttta caaaaactat
    28321 ctgaagaaga tcctactttc cgtgctgaaa caaacgtgga aacaggcgaa acaatcatcg
    28381 ctggtatggg tgaacttcac ttagatatca tcgttgaccg tatgcgtcgt gaattcaaag
    28441 ttgaagctaa cgtaggtgcg cctcaagtat cttaccgtga aactttccgt gctggcactc
    28501 aagccgaagg taagtttgta cgtcagtctg gtggtaaagg tcaatacggt cacgtatgga
    28561 ttgaatttac accaaatgaa gaaggtgctg gtttcgaatt tgaaaatgcg atcgtcggtg
    28621 gggttgttcc tcgtgaatac attccagctg ttgaaactgg tttgaaagat gctatggaaa
    28681 atggtgtctt agctggctat ccattagtag atatcaaagc taaactttac gatggttcat
    28741 accatgatgt cgattcaaat gaaactgcct tccgtgttgc tgcttctatg gcattacgtg
    28801 cagcagctaa gaaagctaat ccagtaatcc ttgaaccaat catggctgta gaagttgtta
    28861 tccctgaaga ttatttaggt gatgttatgg gtcacgtaac tgctcgtcgt ggacgtgttg
    28921 aaggtatgga agctcgcgct ggcggccaac aagttgttcg tgcgatggtt ccacttgctg
    28981 aaatgtttgg ttatgctaca actcttcgtt ctgctactca aggtcgtggt acatttacaa
    29041 tgacatttga ccactacgaa gatgtaccaa aatcagtaca agaagaaatc attaagaaaa
    29101 acggcggaaa agctgaataa tttcttgaaa ccggatagtc ctgcaaagag attatccaaa
    29161 gagactatat ttttaatata gtttcgtgta aaataattat cgatgatatg ggcatgtggt
    29221 gtaccttgtg tacatcatat acctatcaga caaataaaaa atatattgta tttttaggag
    29281 gacattttaa aatggcaaaa gaaaaatttg accgttctaa accacacgtt aacattggta
    29341 ctatcggaca cgttgaccat ggtaaaacta cattaacagc tgcaatcaca actgtactat
    29401 ctaagaaaaa cggcggccaa gctatggctt acgatcaaat cgatggtgct ccagaagaac
    29461 gcgaacgcgg aatcacaatc tcaacagctc acgttgagta tgaaacagat acacgccact
    29521 acgctcacgt tgactgccca ggacacgcgg attacgttaa aaacatgatc actggtgctg
    29581 ctcaaatgga cggagctatc ttggtagttt ctgctgctga cggcccaatg cctcaaactc
    29641 gtgaacacat cctattgtct cgtcaagttg gtgttcctta catcgttgta ttcttgaaca
    29701 aagtagacat ggttgatgac gaagaattac tagaattagt tgaaatggaa gttcgtgacc
    29761 tattaacaga atacgaattc cctggtgacg atgttcctgt agttgctgga tcagctttga
    29821 aagctctaga aggcgacgct tcatacgaag aaaaaattct tgaattaatg gctgcagttg
    29881 acgaatacat cccaactcca gaacgtgaca acgacaaacc attcatgatg ccagttgaag
    29941 acgtgttctc aattactgga cgtggtactg ttgctacagg tcgtgttgaa cgtggacaag
    30001 ttcgcgttgg tgacgaagtt gaagttgttg gtattgctga agaaacttca aaaacaacag
    30061 ttactggtgt tgaaatgttc cgtaaattgt tagactacgc tgaagctgga gacaacattg
    30121 gtgctttact acgtggtgtt gcacgtgaag acatccaacg tggacaagtt ttagctaaac
    30181 caggtacaat cacacctcat acaaaattct ctgcagaagt atacgtgttg acaaaagaag
    30241 aaggtggacg tcatactcca ttcttcacta actaccgtcc acaattctac ttccgtacaa
    30301 ctgacgtaac aggtgttgtt gaattaccag aaggaactga aatggttatg cctggcgaca
    30361 acgtaacaat ggaagttgaa ttaatccacc caatcgctat cgaaaacggt actaaattct
    30421 caatccgtga aggcggacgt acagttggtg ccggtgtcgt tacagaaatc aaagcttaat
    30481 tcacttaagt tttaaagtaa agcaacattt attcggacgt aatcgctcgg aacgaaggtc
    30541 ttaggatctt tgttccgagc ttttttattt attgcaggat caggaaaaaa gacaggagta
    30601 ttataaatag aagaaacacg aaataaaaga gtcagtattt tctaaatgaa actttatgaa
    30661 aacaaaatgt tttttacaag aaaaagcctt gctttgtgag tttatatata ttataatgac
    30721 aaaggtgcgt ttactttagt gaattgcaca gacgtaatca gaatgatttc gtcggctaag
    30781 aaacgagagg ttgcgacacg cccggacgct ttgccacgaa cgagcgtgac ggaaattttc
    30841 gtggagctat gtctactttt caaaataggc gaaggaggga acaagatggc aaaacaaaaa
    30901 attcgtatcc gtttaaaagc gtatgaacac cgtattttag atcaatcagc ggataaaatc
    30961 gtggaaactg caaaaagaac tggagctagc gtgtctggtc caattccatt accaactgaa
    31021 cgcagtcttt acacaatcat ccgtgcgact cataaataca aagattcacg cgaacaattc
    31081 gaaatgcgta cacacaaacg tcttatcgac attgtgaacc caacaccaaa aactgttgat
    31141 gctttgatga agctagactt accatctggt gtaaacatcg aaatcaaatt ataaaactaa
    31201 aacaaaaata atggaggtgt actcatgacc aaaggaatct tagggaaaaa agtgggaatg
    31261 acacaaatct tcactgaatc tggtgaatta attccagtaa ctgttgtaga agctactcca
    31321 aacgtagtac tacaagtgaa aacaatggaa acggatggct acgaagctat tcaagttggt
    31381 taccaagata tgcgtgaagt tttatcaaac aaacctgcga aaggtcatgt tgcaaaagca
    31441 aacacggctc ctaagcgctt cattcgtgaa ttcaaaaatg ttgagctagg agaatatgaa
    31501 gtaggaaaag aaattacagt agatgttttc caagcaggag acattattga tgtaacaggt
    31561 actacgaaag gtaaaggatt ccaaggggtt atcaaacgcc acggacaaag ccgcggacca
    31621 atggctcacg gttctcgtta ccatcgtcgt cctgggtcaa tgggtccagt tgcacctaac
    31681 cgtgtattta aaaacaaacg tcttgctggc cgtatgggtg gcaaccgcgt aactatccaa
    31741 aacttggaag ttgtacgtgt cgatgcagaa agaaatgtta tcttgatcaa aggtaatgtt
    31801 cctggagcta aaaaatcttt aattactatc aaatcagctg tgaaagctaa ataattgtag
    31861 gaagaaagga ggaactaagg aatgccgaat gtagcattat tcaaacaaga tggaagccaa
    31921 aacggtgaaa tcacacttaa cgaagaaatc ttcggaattg aacctaatga aagtgttgtt
    31981 tacgatgcaa tcgtaatgca acgtgcgtca ttaagacaag gaacacacgc ggttaaaaac
    32041 cgtagcgctg ttcgcggcgg cggacgtaaa ccatggcgtc aaaaaggaac aggtcgtgca
    32101 cgtcaaggat ctatccgctc accacaatgg cgtggaggtg gcgtagtctt tggaccaaca
    32161 ccacgttctt acagctacaa acttcctaaa aaagttcgtc gtttagcaat gaaatctgta
    32221 ttgtcagaaa aagttgctga aaacaacttg gtagcaatcg aaggcttgaa cttcgacgca
    32281 ccaaaaacaa aagaattcaa acaagttctt gctaacttat ctatcgactc taaagtattg
    32341 gttgttctag aaaaaggtaa cgactttgct gctttatcag cacgtaactt accaaacgtt
    32401 tctgtagtaa cttctgataa tgtgagtgtg ctagacgttg tatcaaatac aaaagtgtta
    32461 gcaacacaaa ctgctcttac tcaaattgag gaggtgcttg cataatgaac ttactagacg
    32521 taatcaaacg cccagtgatc actgaaaaat caatgcttgc catggatgac aagaaataca
    32581 cttttgaagt ggacactcgc gcaaacaaaa ctttagtaaa acaagcggta gaagctgctt
    32641 ttgacgttaa agtcaaaaac gtgaacatcg tgaacgtacg tgcgaaattc aaacgtatgg
    32701 gcaaatatgc aggatataca aaaaaacgtc gcaaagcgat cgttacattg actgaagatt
    32761 caaaagaaat ccaattattc gaagctgctg aataagcact aatagataac tcattaaatt
    32821 aggagggaaa aacgtggcga ttaaaaagta caaacctacc tcaaatggtc gtcgtaacat
    32881 gacaggttct gattttgctg aaatcacaac atcaacacct gaaaaatcat tgttacaacc
    32941 attgaaaaac catgctggac gtaacaacaa cggccgcatc actgtacgtc atcaaggtgg
    33001 cggacacaaa cgccaatatc gcgtgatcga cttcaaacgt aacaaagata acgttgttgc
    33061 aactgttcaa acgatcgaat atgatccaaa ccgttcagct aacatcgcgt tagtacacta
    33121 tgaagatgga gtgaaagctt acatcttagc acctaaagga ctagaagtgg gtatgaaact
    33181 tgtttcaggt ccagaagcag atatcaaagt cggaaatgct cttccattag aaaacattcc
    33241 agttggtact gttatccaca acattgaaat gaaacctggt aaaggtggac aattgatccg
    33301 ttctgctggt acaagtgctc aagtacttgg taaagaaggc aaatacgtat tgatccgctt
    33361 gaactctggt gaagttcgta tgatcttagc tgcatgccgt gctacaatcg gttctgtagg
    33421 taacgaacaa cacgaattaa tcaacatcgg taaagctgga cgctctcgtt ggatgcgtaa
    33481 acgcccaact gtacgtggta gcgtaatgaa ccctaatgat cacccacacg gtggtggtga
    33541 aggtaaagct cctatcggac gtaaagcacc agtttctcct tggggtcaac cagctcttgg
    33601 ttacaaaact cgtaacaaaa aagctaaatc agacaaactt attgttcgtc gtcgcaaaaa
    33661 taaataatta ctttgaccat gtgtcgcaca ttttgagagg aggttcacca tgggtcgtag
    33721 tttaaagaaa ggaccttttg tcgatgagca tttaatgaaa aaagttgaag ctcaagcagg
    33781 ggttgaaaag aaaaaagtta tcaaaacttg gtcacgccgt tcaacagttt tcccaagttt
    33841 tgttggatat accatcgcag tttatgatgg acgtaaacat gtaccagttt acatccaaga
    33901 agacatggta ggacacaaat taggtgaatt tgcacctaca agaacttatc gtggacatgc
    33961 tgctgacgat aagaaaacga aacgctaatt tgaggggagg ataaatccaa atggcagaac
    34021 aaatcacatc agctaaagca actgcaaaaa cagttcgcac ttcacctcga aaagcccgtt
    34081 tagtaattga ccttatcaga ggtaaaagtg tcgcagatgc aatttcaatc ttgaaattca
    34141 caccaaacaa atctgctgga atcattgaaa aagtattgat gtcagcagtt gcgaatgcag
    34201 aaaataactt tgacttagat gttgaaaact tggtagtaag cgaagctttt gttaacgaag
    34261 gacctacaat gaaacgtttc cgtcctcgtg caaaaggatc agcttctcca atcaacaaac
    34321 gtacaagtca tatcacggta gtcgtatcag aaaaataagg agggataatc agtgggtcaa
    34381 aaagtacatc caattggaat gcgtgtaggc atcatccgcg actgggatgc taaatggtat
    34441 gctgaaaaag agtatgctga gttcttacac gaagatttaa gaatccgtaa atttatttca
    34501 actaaacttg ctgatgctgc tgtatcaaca gttgaaatcg aacgcgcaac aggtcgcgta
    34561 aacatttcaa ttcacacagc taaaccaggt atggttattg gtaaaggcgg ttctgaagtc
    34621 gaaagcctaa gaaaagaatt aaacaaatta actggtaaaa gaatccatat caatatcgtg
    34681 gaaatcaaaa aaccagatct agatgcaaaa ttagtaggtg aaggaatcgc acgtcaatta
    34741 gaaaaccgtg ttgctttccg tcgcgctcaa aaacaagcca tccaacgctc aatgcgtgct
    34801 ggcgctcaag ggatcaaaac tcaagtatct ggtcgtctaa acggagcaga tatcgctcgt
    34861 tcagaaggat actcagaagg aactgttcct cttcatactt tacgtgcgga cattgattac
    34921 gcatgggaag aagcagatac aacatacgga aaactaggag ttaaagtgtg gatctatcgt
    34981 ggagaaattc ttccaactaa aaaaaacact gagaaaggag ggaaataatc atgttagtac
    35041 ctaaacgtgt aaaacaccgt cgtgaattcc gcggaaaaat gcgcggggaa gctaaaggcg
    35101 gaaaagaagt agcattcggt gaatacggtt tgcaagctgt tgattcacat tggatcacaa
    35161 accgccaaat cgaagctgct cgtatcgcaa tgactcgtta catgaaacgt ggtgggaaag
    35221 tatggattaa aattttccct cacaaatctt atactgccaa agcaattggg gtacgtatgg
    35281 gttctggtaa aggggcacct gaaggatggg ttgcaccagt aaaacgtggt aaaatcatgt
    35341 ttgaaatcgc aggcgttcct gaagaagtag ctcgtgaagc gttacgtcta gcttctcaca
    35401 aattaccaat gaaaactaag atcgtaaaac gtgaggaaat gggtggtgaa tcgaatgaag
    35461 gttaaagaaa tcagagaatt aaccactgcc gaaatgcttg atcaagaaaa acaattaaaa
    35521 gaagaattgt ttaatcttag attccaatta gcaacaggtc aattagaaaa cactgcacgt
    35581 attaaagaag tacgtaaatc gattgcacgc atcaaaactg tgttgcgtga acaagctaag
    35641 taattatgga aggaggccat taagcgtatg actgaaggaa gaaatcaacg caaagtttat
    35701 caaggtcgcg tggtttcaga caaaatggat aaaacaatta ccgttgctgt cgaaacaaag
    35761 aaaaaccacc ctatctatgg caaacgcatg aactattcta agaaatacaa agtgcatgat
    35821 gaaaacaaca cagcaaaagt tggcgacatc gtgagaatta tggaaactcg tccattatca
    35881 gctacaaaac gtttccgttt gttggaagta gtcgaagaag cagttattat ctaataacac
    35941 gagattttcc tatatagatt gaatgcaaaa tctgaaagga ggatacacaa cgtgatccaa
    36001 gcagaaagtc gtttaaaagt cgctgataac tcaggcgcac gtgaaatttt gacgatcaaa
    36061 gtccttggtg gatctggtcg taaaactgct aacatcggtg atgtgatcgt tgctacggtt
    36121 aaacaagcaa cgccaggtgg ggttgtcaaa aaaggtgacg tcgttaaagc cgttatcgtt
    36181 cgaacaaaat caggagctcg tcgtacagac ggttcatata ttaaatttga tgaaaatgct
    36241 gcagtgatta ttcgtgatga taaaagccct cgtggaacac gtatctttgg gccagttgca
    36301 cgtgaactac gtgaaaacaa cttcatgaag atcgtttcac tagcaccaga agttttataa
    36361 tcttgagaca cttatcaaag gaggtgcgaa acagttatgt ttgttaaaaa aggcgataaa
    36421 gttaaagtta tcactggaaa agacaaaaac aaagaaggcg ttgtactagc agcgttcccg
    36481 aaaaaagata aagttattgt cgaaggtgta aatgtcgtta aaaaacacca aaaaccttct
    36541 caagctgctc ctcaaggtgg aattgttgag atggaagcgc caattcatgt ttctaacgtg
    36601 atggtggttg actctactgg tgtagctggc cgagttggct acaaagaagt agacggcaaa
    36661 aaagtccgtg tttctaaaaa aaccggtgaa gttttagata aataaaagtt taaggaagga
    36721 gggtcttact gaatgaaccg cctaaaagaa aaatatctta aagaagtaac tccatcattg
    36781 atggaaaaat ttaactatag ctctgttatg caaacaccta aagttgaaaa aatcgtcatc
    36841 aacatgggtg ttggtgatgc ggtatcaaac gctaaaaact tagataaagc agttgaagaa
    36901 ttaactttga tcactggtca aaaaccaatg attacaaaag ctaaaaaatc aatcgctgga
    36961 ttccgtttac gtgaaggaat gccaattggt gcaaaagtta cattgcgcgg agaaagaatg
    37021 tacgaattct tagacaaatt ggtttctgtt tcactaccac gtgtacgtga cttccatggt
    37081 gtaagtaaaa aagcctttga cggtcgtgga aactatactt taggtattaa agaacaattg
    37141 atcttcccag aagtagatta tgatttagta gataaagtac gtggtatgga catcgttatt
    37201 gtaacaacag caaactctga tgaagaatct cgtgagttgt tgacacaatt aggcatgcca
    37261 ttccaaaaat aattaaagga ggcgaactac gtggctaaaa aatcaatgat tgctaaaaac
    37321 aaacgtcctg caaaattttc aacacaagct tatactcgtt gcgaacgttg cggacgtcca
    37381 cattcagttt atcgtaagtt ccatctttgc cgtatttgct tccgcgaact tgcctataaa
    37441 ggtcaaattc ccggcgtgaa gaaagctagc tggtaaaaag taaattcgca taagaaggag
    37501 gtaaaagatc aatggtcatg acagatccaa ttgcagattt tctaactcgt atccgtaacg
    37561 caaacatggt taaacatgag tctttagaag tacctgcatc aaaaattaaa cgtgacatcg
    37621 ctgaaatctt gaaacgtgaa ggtttcgttc gtgatgttga atacatcgaa gatgacaaac
    37681 aaggcgtgat ccgtgttttc ctaaaatttg gtaaaaacgg cgaacgtgtt atcacaaact
    37741 taaaacgtat ctctaaacca ggtttgcgtg cttatgtcaa agctgacgaa gtaccaaaag
    37801 tattgaacgg tttaggtatc gcaatcattt cgacttctga aggtgttgtc actgataaag
    37861 aagctcgtga aaaaaatatc ggcggcgaag ttatcgctta cgtatggtaa tcaagtagaa
    37921 tctacaagga ggtgtcttta agtgagccgt atcggaaata aagtcgttgt tatccctgaa
    37981 ggagtaacag ttactcaaga cggaaacaac gttacagtta aaggaccaaa aggtgaattg
    38041 actcgtactt tttcagcaga tatcaaaatg aatatcgaag gaaacgaagt aactttcact
    38101 cgtccaaacg acagtaaaga aatgaaaaca attcatggaa caactcgtgc gaacttcaac
    38161 aacatggttg taggtgtcag cgaaggtttc caaaaagcgt tagaactaat cggggttggg
    38221 taccgtgcac aattacaagg atcaaaactt gtattgaacg ttggttactc acatccagta
    38281 gaaatcacac caccagctgg agtaactgtt gaagtaccag ctaacacaca agtaattgtt
    38341 aaaggtgcga acaaagaaga agttggcgaa ttagctgcaa acattcgtgg aactcgtcct
    38401 ccagaacctt ataaaggtaa aggtattcgt tatgttggcg aatatgtacg ccgtaaagaa
    38461 ggtaaaactg gtaaataatc gtttagaaaa attgcataga agccagcagc aggaaaaagg
    38521 catttggctg aagtttacct tcaaaaaaat acatttttac ttgtgccgca gcttctattt
    38581 ttcgaaacgt atttactgct tgaaatagta gtacaataaa aataaagagg tgacaattgt
    38641 gattacaaaa ccagataaga acaaaacacg tcaaaagaga catcgtcgtg tacgtaacaa
    38701 tatctctggt actgctgagc gcccacgctt gaacgttttt cgttctaaca aaaacatcta
    38761 cgctcaaatt attgatgacg tagcgggtgt aacgctagca agtgcctcta ccttggataa
    38821 agaaatttca ggtggaacaa aaacagaagc agcacaagct gtcggtaaac tagttgctga
    38881 acgtgcagct gaaaaaggca ttaaagtagt agtctttgac cgtggtggat acctttacca
    38941 tggccgtgtg caagctttag ctgaagctgc tcgcgaaaat ggactagaat tttagaagaa
    39001 ggaggaatac cattcatggt ttatatcgat ccaaaacatt tggaattaga agaccgcgtt
    39061 gttgcaatta accgtgtaac aaaagttgtt aaaggtggac gtcgtctacg ttttgctgct
    39121 ttagttgttg tcggtgacaa aaacggacac gtaggatttg gtacaggtaa agctcaagaa
    39181 gttcctgaag caatccgtaa agcaattgaa gatgcgaaga aaaacttagt tgaagtacct
    39241 atggttggtt caacaatccc acacgaagta atcggtgctt ttagtggtgg tagaatccta
    39301 atgaaacctg ctgtagaagg ttctggggtt gctgctggtg gaccagttcg tgccgtatta
    39361 gaattagctg gggtagcaga tatcacttct aaatctttag gctcaaatac accaatcaac
    39421 gttgttcgcg caacagttga aggtttgaaa caattgaaac gtgcagaaga agttgcagaa
    39481 cttcgcggca aatcagttga agaattaatc ggataaggag gacaacaata atggctgaat
    39541 taaaagttac tttaaaacgc agtattatcg gacgtcctca aaaccaacgc gatacagtta
    39601 aagcgttagg tcttacaaag attaacagtt cagtggttaa gccttctaat gaagcaatta
    39661 aaggcatgat caatactgtt tctcacctag tggacgttga agaaatttaa tttagaaaaa
    39721 tcataactag aacattaagg aggtgccaaa cctatgaaac ttcatgaatt aaaacctgct
    39781 gaaggttcac gccaagtacg taaccgtgtt ggtcgtggta cttcatctgg taacggaaaa
    39841 actgccggac gcggacaaaa aggacaaaaa gctcgttcag gcggcggtgt gcgtttagga
    39901 tttgaagggg gacaaacacc attgttccgt cgtttaccaa aacgaggatt cacaaacgtg
    39961 aaccgtaaag actatgcagt cattaatctt gatgtattga accgctttga agacggagct
    40021 gaagtaactc ctgttgcttt agttgaagct ggaatcgtga aaaacgaaaa agctggaatc
    40081 aaagtattag ctaatgggga actaaacaag aaattaactg tgaaagcagc aaaattctct
    40141 aaagcagctc aagaagcaat tgaagcggct ggtggatcaa tcgaggtgat ctaatgttta
    40201 gactattaaa agatgctttt aaagtaaaag acattagatc gaaaatccta tttactgtat
    40261 ttgtgttgtt tgtatttcgc ctaggtgcac atattactgt accaggcgta aatgctgctt
    40321 cattgcaaaa cctttcttct ttgccatttt tcaacatgtt gaacttggta agtggtagtg
    40381 cgatgcaaaa cttttccatt ttctcaatgg gggtttcacc atacattact gcttctatcg
    40441 tcattcagct tcttcaaatg gacatcgtgc ctcgatttgt tgaatggtcg aaacaagggg
    40501 aagttggtcg taaaaaactg aatcaagcga ctcgatatct gacattagta ttggcattta
    40561 tccaatctgt cggtatcact gctggattca atcaatacgc tcaattaggt ttcgtgaata
    40621 atcctaacgt agcaacttac gtaacgatcg gtttgattct aacagccggt acgatgtttg
    40681 ttacttggct aggagaacag atcacagaaa aaggtatcgg aaatggcgta tcaatgatca
    40741 tttttgcagg tatcatttct agattgcctg aaagtatcag agaaatttat gaagattact
    40801 ttataaatat tgatccttca gacatatgga aatctgctat ttttgtggcc attttactag
    40861 tagcggtctt gttgatcgtg acattcgtaa catttttcca acaagctgaa cgcaagatcc
    40921 cgatccaata tacgaaacgc gtagctggcg cgcctacaag cagctatctg ccgttgaaag
    40981 taaatgcagc tggagttatt ccagttatct ttgctagttc gtttattgct acgccaaatg
    41041 ctgttttaca agcattgagc ggtagattcg gttctgaaaa ctggtacaaa gtgatgatgg
    41101 agatctttaa ctataataca gcacctggtg ctacgattta tacgattctg atcgttgcct
    41161 tcactttctt ctacgccttt gttcaagtaa accctgagaa attagcggaa aacttgcaaa
    41221 agcaaggaag ttatatacca agcgtacgcc ctggtaaggg gactgaagag tatgtctcaa
    41281 gattactgat gcgtttaagt acagttggtg cagtcttcct tggtttagtg gcattgcttc
    41341 caatcattgc tcaaatggtt tgggatcttc cacaatcaat cggattaggc ggtacaagct
    41401 tactgatcgt tatcggtgta gctttagaaa ctgcgaaaca gttagaaggc ttaatgctga
    41461 aacgtaaata tgttggattc attgagtaag aaagcgtgtt gaggtttccc ctcaacacac
    41521 gttctcacac atttattagg agggaaaaca atgaacctca ttttaatggg gctgccaggc
    41581 gcaggtaaag gaacacaagc tgaaaaaatc attgatgctt atggtattcc gcacatctca
    41641 acaggagata tgttccgcgc agcgatgcaa aacgaaacag ctcttggcct ggaagcaaag
    41701 tcttatatgg ataaaggtgc attagttcct gatgaagtaa caaatggaat cgtgaaagag
    41761 cgactagctg aaccagatac agagaaaggc ttcttattag atggctttcc acgtacgcta
    41821 gatcaagcaa aagctctgga cgcaatgcta aaagatttga ataaaaaaat tgatgctgtc
    41881 atcgatatcc atgttggtga agaaatcttg gtcgaacgtc tagccggccg atttatctgc
    41941 agcaattgtg gagcaactta ccataaaatt ttcaacccta caaaagttga agacacatgt
    42001 gatcgttgcg gtgggcatga attctatcaa agagaagatg ataaacctga gacggttaaa
    42061 aatcgtctgg ctatcaacat caaaaatagt gaaccaatct tggcttatta taaagaacaa
    42121 ggtttgctaa acactattga tggtgctcgt gaaatcgatg ctgtatttgc agatgtacaa
    42181 aaaatcattg aaaaatagca cgattgcccg tagccgactt gcattatgca gttactcttg
    42241 tcaagttcaa taaattatga tagaatatgt cagtccgact tctagagaat cctctagatg
    42301 atccattttg agaattttga ggtgggaact gcagtttccg ccattttatc gtgtgaaaat
    42361 gcgaaacaag tacaaggagg tactgtgcgt ggcaaaagaa gatatgattg aagtcgaagg
    42421 tacagtcgtc gaaactttgc cgaatgcaat gtttaaagtt gaactagaaa acggacacca
    42481 agttcttgct actgtttcag gtaaaattcg tatgcattac atccgtatct tacctggtga
    42541 caaagtaacg gttgaattgt ctccatacga tcttaaccgt ggccgtatta cttatcgctt
    42601 taaataattg tactccgtaa aactacagga ggtattatca tgaaagtaag accatcagta
    42661 aaaccaatgt gcgaacattg taaagtaatt cgtcgtaaag gacgcgttat ggtgatttgc
    42721 ccagcaaatc caaaacataa acaacgtcaa ggataattgg aggtgctata aatatggctc
    42781 gtattgcagg agtagatatt cctcgtgata aacgtgtagt agtttcactt acttatatct
    42841 atggtattgg taacactact gctaaaaaga tcttagctga tgctggtgta tctgaagatg
    42901 ttcgcgttcg tgaattaacg aatgaacaaa cagatgctat ccgtgcagaa gtagataaat
    42961 taaaagttga aggggatctt cgtcgtgaag tgaacttgaa catcaaacgt ttgatggaaa
    43021 tcggttctta ccgtggaatc cgtcatcgcc gtggattgcc tgttcgtgga caaaacacga
    43081 aaaacaatgc acgtactcgt aaaggcccag ctcgcgctat cgctggcaag aaaaaataat
    43141 tcttaagtga aggaggttaa aacttcatgg cagcaaaaaa agtgaatcgt aaacgccgtg
    43201 tgaagaagaa tatagaagca ggtattgcac atatccattc tacattcaat aacactatca
    43261 tcatgatcac tgatactcac ggaaatgcat tagcgtggtc atcagctggt tcattaggtt
    43321 tcaaaggaag caaaaaatca actccttttg ccgctcaaat ggcagcagaa actgctacaa
    43381 aagcagcaat ggaacacgga ttaaagactg ttgaagtaac agttaaagga cctggttctg
    43441 gacgtgaagc agcaattcgt tcattacaag ctacaggttt agaagtgact gcaattcgtg
    43501 acgtgactcc agttcctcat aatggtgccc gccctccaaa acgccgtcgt gtttaatgag
    43561 tgccgctcat tttgagtttt atcagtaacg tcattgaaca agacactttt cgttttgaaa
    43621 ggggtaaaga taagaatgat tgagttcgaa aaaccaagaa tcgcaaaaat tgatgaagaa
    43681 aaagattatg gcaagttcat cgttgaacct cttgaaagag ggtatgggac tactttaggg
    43741 aattccctac gtcgtatttt attatcttct ttgccaggtg ctgccatcac taatattcaa
    43801 atcgatggtg tactgcatga attctctacc atcaaaggtg ttagagaaga cgtcactcaa
    43861 atcatcttga acattaaagg cttagcgctg aaaatgtatg gccaagaaga aaaaaccctt
    43921 gaaatcgata ttaccggacc tgctacagta actgctggcg atattatcgt tgatagtgat
    43981 gtagaaattc ttaacaaaga tatgtacatc tgtagtgtct ctgaaggagc tacgttccat
    44041 gctcgcttaa cagtgaaacc tggacgtggt tatgttcaag cagatgaaaa taaaaaagaa
    44101 gatatgccaa ttggcgttct tccagtcgat tcaatctaca cacctgttcg tcgtgtgaac
    44161 tatcaagttg agaacacacg tgttggacac cgtgaagatt ttgataaatt gacgatggag
    44221 atttggacag atggttcaat tgaaccgttg gaagcaatga gtttgtctgc gaaaatcatg
    44281 actgaacatt tggatatttt tgtgaactta actgatgaag caaaaaatgc tgaaatcatg
    44341 gtcgaaaaag aagaaacaca aaaagaaaaa atgttggaaa tgacgatcga agagttagac
    44401 ttgtctgttc gctcttacaa ttgtttgaaa cgtgcaggaa tcaatactgt acaagaactt
    44461 acaaataaat ctgagcctga aatgatcaaa gtccgtaact taggacgtaa atcattagaa
    44521 gaagttaaag caaaattgca cgacttaggt ttaggtttac gtaaagaaga ttaaaacctt
    44581 ttacgaagga gggaaaccaa cgtgagttat cgtaaactag gacgcacatc tagccaacgt
    44641 aaagcgatgt tgcgtgattt aacaactgat ttattaatca acgaacgtat tgtgactact
    44701 gaagctcgtg cgaaagaagt tcgctcaact gcagaaaaaa tgatcacttt aggtaaacgc
    44761 ggagatttgc atgcacgtcg tcaagctgcg gctttcgtac gtaatgaagt tgccagcgtg
    44821 cgtgaagaaa atgaggacat cgtcattgaa tcagctttac aaaaactgtt caacgatatt
    44881 gcacctcgtt acgcagaacg tcaaggcgga tacacacgca ttttgaagac agaaccaaga
    44941 cgcggtgatg gtgcaccaat ggttgtctta gaacttgtct aaaatcacac taataacatc
    45001 actttataga tgattctttt agagtgttat gatgttggaa gatatttttc cgagtctagc
    45061 tcagcgctgc tcctcaagcg aatatcgctt ggggagtaag cactcatcat aaagtgtttt
    45121 tttatacctt caattacctg tcatgacaga tatgtttgaa ggcataaaaa aacattttaa
    45181 gcgagaaata attgaaaatt ttgtcttttt ttgatagtgt tagtaggaac tttaggatga
    45241 agaaggagta atcatggagc caattattga attagaaaag ataaattata aataccagcc
    45301 agatgatctt cgccccgcat tgaaagatgt ctcctttaca attgataaag gtgagtggat
    45361 cgctattatt ggacacaatg gttcaggaaa atcgacactt gccaaaacga tcaatggatt
    45421 gcttctgcca gaatcaggga tcgtgaaagt gggaaatcaa atattggatg aagaaaatat
    45481 ttggacgatc cgacagatgg ttggaatggt ttttcaaaat ccagacaatc agtttgttgg
    45541 ttcgacagta gaagatgacg ttgcttttgg tcttgaaaat caagggattc ccagagaaga
    45601 aatgctagtg cgtgtgaaag atgcacttga gaaagttaga atggctgagt ttgcttcacg
    45661 cgagcctgct cgtttatcag gagggcaaaa acaacgtgtt gccattgccg gcgtggttgc
    45721 cttacgacct gatatcatta ttttagatga agcaaccagt atgctagatc cagaaggtcg
    45781 tgaagaagtg atctctacga tcaagaagat caaagaagaa agtcaattga ccgttatatc
    45841 tatcactcat gatattgatg aagcagctaa tgccaatcgg atactagtga tgagacaagg
    45901 cgaacttgtc cgtgaaggta caccaaaaga aattttttct gctggtcctg aactgatcga
    45961 cttaggtcta gatctaccat ttcctgaaaa actgaagagc gcactgaaag aacgtggggt
    46021 tgatgtgccc agtgaatata tgacagaaga aaggatggtg gattggttat ggacatccgt
    46081 tttgaacaag tagacttcac ttatcagccg aatacaccat ttgaacaaag agccttattt
    46141 gacatcaata tgacgatcaa agaaaacagt tatactgcat tagtagggca taccggaagc
    46201 gggaaatcaa ccttacttca gcatttgaat gcgcttgtta agccaacaag cggtacagtc
    46261 catattggag aacgagatat tcagccggat acggataata agaatttaaa gcccatccga
    46321 aaaaaagttg gcatcgtctt tcagtttcca gaagcacagc tattcgaaga aacggtagca
    46381 aaagacattg ctttcggtcc taaaaacttt ggtgtcagcg aagaagaagc actagtccta
    46441 gcaaaagaaa cattagaaca agttgggctg gatgaaagct atttggaacg ttcgccattt
    46501 gaactttcag gagggcaaat gcgtagagta gcaatcgctg gtgtgcttgc catgaggccg
    46561 gaagtacttg tattggatga accaacggca ggacttgatc cccagggcag aaaagaaatg
    46621 atggagatgt tttggcgtct tcataaggaa cagcagatca ctattgtatt agttacgcat
    46681 ttaatggatg atgtagccaa ttttgcagat tatgtctatg tgttggaaaa gggacgaatc
    46741 gttaatagcg gggagccgca agaggtcttt caaaacattg aatggctaaa agaaaaacaa
    46801 ctaggcgtac ctactgccac cgagtttgca gaagaattaa tggctaaagg gatgaacttt
    46861 gctaccttgc ctttgacagc tgaagaatta gcagacgcta tcgtccatta tgctggagga
    46921 aatgcccatg atgaataaat tgatatttgg tcgttatatg cctggagatt ccttgatcca
    46981 tcgattggat ccccgagcta aattattagc cagtttttat tttatcggaa tcattttttt
    47041 agcaaataat tgggaaacgt accttttgtt ggcatttttc acattacttt ctgtcttctt
    47101 gtcaaaagta gatttgaaat tttttatccg aggcattcgc ccattgatct ggctaatcct
    47161 cttcactgta gctttgcagg tcttgtttac aagtggcgga gaaacttatt ggagttgggg
    47221 tgttttccat atcactgaat ttggtgtgat gaacggcctc tttattttct gtcgattcgt
    47281 gttgatcatt tttatgtcga ctctactcac gcttactaca ccgcctttgg aattatcgga
    47341 tgcgattgag tacttgcttc gtccattgaa agccgtacgg ttcccagtcc acgaaatttc
    47401 attgatgctg tcgattgctc ttcgttttgt gcctacattg atggacgaaa cagaaaagat
    47461 catgaacgct cagcgcgctc gcggtgttga ttttggtgaa ggaaacctag ttcagaaaat
    47521 gaaagcagtc attcctttgc tgattccttt atttgtcagc agcttcaacc gtgcggaaga
    47581 tcttgcgact gctatggaag caagaggcta caaaggtggg gaaggaagaa cgaaatatcg
    47641 tgtattgcat tggcataata gagacacgat ggttatcatt gcttttgtat tattaactgt
    47701 gctactgatc tttttaagag gataaacgtt cagtgggccg ctatctattc ttttcttgct
    47761 gatctgtttg caagaaagga tgcaagcagt gtatgacaag aaatattagg gtctgtggca
    47821 gactaaggtc acaggcctct ttcttttatc tgaaaagaaa gaacgaaaaa attttataga
    47881 aaaatcatta ttccagataa ccttttagga acaaaggaga gaaaaacatg gtacgttaca
    47941 aagcaatcat tgcgtacgac ggaacaaatt ttaatggatt ccaaaaacag ccaaatgggc
    48001 gtactgttca agaagaagta gaaaaaacat tacaaaaaat ggcaaatgga aaagaaatca
    48061 cggtctttgg ttcgggaagg acagatgccg gagtacatgc gatcgggcaa gtaatccatt
    48121 ttgattatcc agaggagcgt ccgttagaac gaatgcgttt cgcgctagat acccagtcac
    48181 cagaggatat tgctgtaaga caagtagaaa ttgtttcaga agacttccac gcaagatatt
    48241 tggtcaaaga aaagacgtat caatttcgag tggatatagg gaaaccacgc agtccttttc
    48301 gacgccatta tgcaagttat tttccttacc cacttgattt ggaaaaaatt cagcgggcgc
    48361 ttcctgattt attagggact cacgatttca cctctttttg tgcatcagga agctcgatag
    48421 aggataaaat acgtacgatc tacgaggcta agatggaggt aaatgaaaca aaagacgaat
    48481 tgttgtttac atttagggga aatggcttct tgtataagat gatacggatc ttagtaggaa
    48541 cgcttttgaa aattggcaat ggccgattgc ctgaagatag tatcccagat attattgcga
    48601 aaaaagatcg taatgcagca ggacctacag cacaccctga aggactttat ttgtatgaag
    48661 tgaaatatga ataagaggtt atgatagaag tggtcagctt caagaaataa gaaggtattt
    48721 acgaaaatta cttctcaaaa ttttgcaaaa tttcggctta ttttcgaaga agctacttct
    48781 ggaacaccgt ttaaggaaga ggtcgtgaaa tcagcgtttt gacctgagta ttagagaaac
    48841 aaacgggaaa atagctcctc atattttgcc gtttgttgag ctaataccga aggtcagctg
    48901 attgaacacc gtttaagaaa gaggtcgtga gcctgtcatt taactctgag tcacaaagag
    48961 caatttcaaa aaacagcttc tcatctttga tgaatatcgt gacttgtgga cgaggcgttg
    49021 ataagtgaat catctttttg ttacctattt tttctgtaac caaaaaacga tggaacgttg
    49081 ttttgattgc ccttggtgcg gacagtctga acaggttcca tcgtttcttt attttctacg
    49141 tcttcttctg tgtgtgtttc gtggttgttc ttctattgct ggatcaatcg tgccataaaa
    49201 ggggcgattg cggtcaaggt accagacata aagaataaac aatgcaatac ataggacaaa
    49261 aaggattgca cctatcgtaa atccttcagg caagtaactg aaagtgacag tatgtttacc
    49321 tgctggaact tttatcatca agaatgcgtc tttgaaattg ctgaccttga ctggtttccc
    49381 atcaatttta gctttccatc ctttgtcata aggaatagtt gtcaccaaca tggaatcttc
    49441 agcggtattt acagtcccag aagcttttct gccagtggct tccatttcga cacctttttc
    49501 tttgatctga ttcattgcgg cttgataggc tacaacatct agaccaacga ctttaggctc
    49561 catgaaactt atttctttcg tcccataaaa acttgcagta aatgtcactg ttgtctcttg
    49621 aggataatag ccaagatcat agtattgacc agaaatgttg atttgcgttt ttcgcgatgt
    49681 accattgaca gtgatcgtcg cactagaact ttctaattgc gcaaaattgg ttgggaacaa
    49741 acttaagtaa gcttgtgtat ttgcaggcac atggacttcc caagtgagct cttttggctg
    49801 gttatctgct gtttctgagt aagtgacgcc agtcgttgtc tttgtgatcg tcgtattcaa
    49861 ctgattcttc aaagtaggtg tatagaatgt aaaatactgt tcatttagac cagacaatgt
    49921 attgatcaag tttgtctgac tggtcaaatt atctgtcact ggctgctcaa catcattaac
    49981 ggacaacggt gcagtaaatg ctagtggcaa tgcattgaca ttctgataca gtgtatagtc
    50041 gccgctttga ccagcttggc ggaagccata tttactgaac gtgctttcgt ttttagaaat
    50101 gttatatttg attcctgtaa acccatccat cagcaaagta ttattgttat aacggatatt
    50161 caaatttgtc cctcttgaac ggaaacctaa tttatccagg taagaggaag aattacgatt
    50221 tcttatagaa gaaaacaaac tgataccact gtaaccatag ttgatcgaat cgtttgcaga
    50281 tactggatcc agattttcca agcggtaaaa cgagtcggaa tctttttttg tttcatttac
    50341 aagagctttc aagtcaggat aaggatcagt atataaactg cgggaagcat aattccaatc
    50401 atcaagaatg ccatggatca tactgttcgt attgaccagt gcttcagcag acatgatcaa
    50461 taataacaat atactcagat gattgaatga aagtttttta tgctgataaa atcccacagc
    50521 aaaagcataa atccctaaga aaaccactgt caatacaaag gaagtcatcg tcacataggt
    50581 gtagcttcct tcaggtttga tgccccatgc caccgcaaag agagcagcta cgaccaaaat
    50641 gattcctaac aacagcccac gatcgtcttg ttctatcttt tcccatcctt ttcctgcaag
    50701 caggagcact aagaaagaga acagataggc ataacggaat aaaaacatat tcggtgcatg
    50761 cataccatgc cagaacaaat tcaatggaac aagataaaaa cttgcgataa gtatggcgaa
    50821 aagactgccg tacaaaaatt tatttttcaa cggtactttc cgactggcaa aataaaacag
    50881 acagaggact aatggtagca gacctgcgta aacgaacgga atcgatccgt attttgtcgt
    50941 gtcataaaca ccaatcatat ttttcatgat tagatccaga taagaagtcg cttctgtttt
    51001 caacgtagtg atctgactca gtgcctcgcc atttgaccga agatccagca ctgctggcaa
    51061 tacaatgatc attgaagcgc cgcctgccag taaagaagtg ataccataag gaacaatcgt
    51121 ttttttatat tctgaccagt ttgtcaatag acgggcgata aaatataaga aagaaaatac
    51181 gccaatcata aaacccatat aaaaactgga taaaaacaag agtaaataac tgataaataa
    51241 aagtttcggc cgtttaagat ccataacacg atgaatcccc aaaatcacta atggaagata
    51301 aaaaaatgca tccagccaca tgatgatctc cgaatgtgca gtgataaatg agatcaatgc
    51361 gtaactgacg ctaagtgcaa catgccccca gcgaggaatc ttgaacgtac gtgcaagaaa
    51421 ccaaaaagcc aatccggcac agccgacctt aagcaaagtc agaacataca gtgcatctgg
    51481 catcatctgg tttggaaaaa agaacaccag tggcgtgaag atcccgccta gatagtaaga
    51541 aattaaagat aaataattca atcctagaga agcattccat gtataaaaaa tactttgctt
    51601 tccaagaaga acatttcgga agctggcatg aaaattagaa aactgtgaaa aggcatcact
    51661 tgccaaaata cttctgctgc ttccaggata gattccgata cttagataaa caagtgctaa
    51721 aatcaaaaac ggaatcagga aactagctgc tgcgtagcgt ccgttttctc taaagaatga
    51781 ctttaaattt tttttcatat ttattttcca ccaaatttct atgaagttgt attcagttta
    51841 tcatatcctt gtttttctct gcttaaaaag agtctagttt tcacaaaaaa ataaaattta
    51901 gaataaataa cttcataatt tgttcgtata acaaaaataa acgcaaaaaa agggtaggaa
    51961 tcaaaagtcc cacccttaaa aatttttatt aaataaaaaa ccgttcacta tctgaacggt
    52021 ccaagtatca ttcaattaaa cgcgttcaac ttttcctgat ttcaaagcac gagttgacac
    52081 ccaaactttt ttaggttttc cgtcgaccat aacgcgaact ttttgtaagt taggtttaac
    52141 agtacgtttt gttgagttca tagcgtgtga acggttgttt ccactttttg tcttgcgacc
    52201 tgtaaagtaa caaacttttg ccatggtaat ttcctccttt gccttgattt ggagcaatag
    52261 aataattcag ctcataccag actaacatat catatagaat gggaatttgc aagtacattt
    52321 tcatagatac aattgacaat tgagaagaat aattgtaaat taaacaaggt tatacctgaa
    52381 attttgcaag gtttttgagt actttgggta actgcctttt atttcaagtt gcgctatgat
    52441 aaaatatgat agaagaaaaa tgggagtttt ttacccgtta aggaggctca ttcatggctg
    52501 taaaaattca aacgtcagct ggaaccattg aaattaccaa tgatgtaatt gcaacagttg
    52561 ttggtggcgc cgcgacagat gtgttcggtg ttgtaggaat ggccagcaaa aatcaaatta
    52621 aagataatat tactgagatt ttgcgtaaag aaaattactc aagaggagta gttgtccgcc
    52681 aagaagataa tggtattgct gtagatgttt atacgattat cagctatggt acgaaaatct
    52741 ctgaagtttc ccgcaacgtc caagaaaaag tgaaatacaa tctagaggca ttattaggcg
    52801 taactgccaa ttcagttaat gtctttgtac aaggtgttcg tgtactgcca gactaggcag
    52861 gagactggct ggtaactcag cagtcgatct gaaggaggat tatctaggtg agtgtaacag
    52921 aaataagtgc aagccagttc caggaaatgg tccaggcagg tgcgaatcgt ctgcaagtaa
    52981 atgcagaata cgtcaattca ttaaatgtat tccctgtgcc agatggcgat acgggaacaa
    53041 atatgaatct atctatgact agtggagcta aggcagtagt agattcaacc tcagaaaaag
    53101 taggagaatt agcagcaatg ctttcaaaag gattgctgat gggtgcgcgc ggaaattccg
    53161 gcgttatttt gtctcaattg tttcgtggat tttctaagca aattccagat gttgtctcat
    53221 taaatgcttc tgatcttgct gcagccttca ctcatggagt tgaaactgcg tataaagcag
    53281 taatgaaacc agtagaagga acgattttga cagtagctag agaagcagcg aaagctggag
    53341 aaaagaaagc aaaaagtact gatgatgtcg ttgaagtaat gacagctgtt gtaaaaggag
    53401 caaagcgtgc tttagctaaa actccagact tgcttccagt cctaaaagaa gtcggtgtcg
    53461 tagacagtgg agggcaagga ctgctgtttg tttatgaggg ctttttaagt gcattgaatg
    53521 gagaattcca agcggatgaa acatatgaac cttctccagc agaaatggat gatatggtca
    53581 atgcagaaca tcatcgcagt gtccaaggtc aaatggcgac agaagatatc cattttggtt
    53641 actgtacaga aatcatggta aaaatcggag aaggacctac agtcgatagt acattcgatt
    53701 acgaagaatt ccgtaactat ttagatggta taggagattc tttacttgtg gtcaatgatg
    53761 acgagatcat caaagtccac gtgcatacag aaaacccagg agaagtcttg aattatggac
    53821 aaaaattcgg ttcattagtc aaaatcaaag tcgacaacat gcgcttgcag catgagacga
    53881 ttttggaaca cgatgaagaa gtgaacgagt ttgcgaaaaa agaaatacca cgtatcccgt
    53941 atggtatcgt agcgatcgct gctggtaaag gcgtccaaga gctgtttgaa agtttaggcg
    54001 ctaattatgt tatcagtggt ggacaaacaa tgaatccaag tacggaagac attgttaaag
    54061 cgattcaaga agtaaacgca gataaagtga ttgtcttgcc aaacaataag aacatcttca
    54121 tggcagctga tcaagcagca gaagtagcag atatcccagt agcagttgtt ccttcaagaa
    54181 cgatttccca aggattgaca gctatgcttt cattcaatga tcaagcttct ttagaagaaa
    54241 acaaagaaac gatgacagaa atgttgtcta gcgttgtgag cggtcaagtc actcacgcga
    54301 tcagagatac ctcaattgac ggtgtagaga tcaaagaagg agactttttg ggcatgatcg
    54361 atggaaaaat cctgatctct aacccagata tcacagcaac agcgttaagt acactagaac
    54421 aaatgatcaa tgaggacaca gagatcgtaa cgatcttggc aggtgatgaa ggaacagttg
    54481 aacaagcaaa tgaatttgct gagaaactaa cagaaaaaca tcctgatttg gaaatcgaga
    54541 tccaccaagg agatcagcct gtctatcctt atctattttc tgctgaataa tttctgtgtc
    54601 agaatatctt tctaacacag tattcattca taaaaggcct tcggttagtg atcaggtatg
    54661 atcgctgacc aagtcctttt tttgttaaag gagggaggaa aaatttatgc gttctttaga
    54721 tgatccaatc actatgctgg caggagtcgg agaaaaaaga gcagctagtc ttgccagctt
    54781 gggcatccaa acgattgaag acttactgac ttattatcct tttcgctacg aagatattca
    54841 ggaaagaaat ctaaacgaga tccaggatca agaaaaggtt actttgaaag gaatcgtagt
    54901 ctcgcctcct gtgatgaatc gatttggtta taaaaaaagc cgattgcaat ttcgtatgat
    54961 gcaagaacat gatgtgttca acgtttcttt ttttaatcaa ccttatctaa aagaaaaagt
    55021 cattttatcg gaggaaatcg ccgtatacgg taaatgggat gcaaagcgta aagccttgaa
    55081 cgggatgaag attttaggtt ctcaaacaat ggatgacttt tcgccgatat atcacgtcaa
    55141 caaatcaatt cgtcaaacga cattagttga tctaatcaaa aaagggtttc aagaatacgg
    55201 cacattgatt gaagaaaatc tgccaaacaa ccttgtggag aaatatcgac tgcttgaccg
    55261 agcttctgct gtaagaagta tgcattttcc aaaagaccac gaagaaaacc atcaagccaa
    55321 acgacgtgtc gtttttgaag agttcttttt atttcaaatg cgtcttcaag gattgaaaaa
    55381 agcagaaaaa gcagaaacga atggtttgga gatcctttat gatgtccaaa aattgaaaca
    55441 atttactcaa aagctacctt ttgaactgac aaatgcacaa aaacgtgtaa cgaatgaaat
    55501 ctgtcgggat cttcgcagtc cgcagcatat gcagcgactt ttgcagggag atgtaggtag
    55561 cggaaaaaca gtggttgccg cgattgcgtt atacgctacc gttacagcag gtttccaagg
    55621 tgcgttgatg gtgcctacag aaatcttggc acaacaacat atggaaagct tgcaacagct
    55681 gtttgatccc aatgaagtaa ccatcgcatt gattacgggg tcaacgaaag caaaagaacg
    55741 acgtgagctc cttgaaaaac tagagcaagg ggaaattaac gtcgtgatcg gcacacatgc
    55801 attgatccaa gatggagtcg aatttcagaa tttaggtcta gttattacgg atgagcagca
    55861 ccgttttggc gtgaaccagc ggaaagtact tcgtgaaaaa ggctggcgac cagatgtctt
    55921 atttatgaca gcgactccga ttcctagaac attagctatt acagcatatg gtgagatgga
    55981 tgtatctatc attgatgaac ttccagctgg acgtatcccg atcgaaacac gctgggtaag
    56041 aacacctcaa ttggacagtg tactggattg gacgaaaaaa gaactggcaa gaggacatca
    56101 aatgtatgtc atctgtccgc tgattgaaga atcagaagca ttagatgtaa aaaatgcagt
    56161 ggaaatctat gaaaaacttc gtgaactatt tgcaccaaaa tatgaagttg gcttgttaca
    56221 tggtaaaatg aagaatcagg aaaaagaagt aatcatggaa gccttcaaag acaaccagat
    56281 gcagatatta gtttcgacta ctgtaattga agtaggggta aacgtgccga acgcgaccgt
    56341 catgctgatc atggatgcgg atcgatttgg attggcacag ctgcaccaac ttcgtggacg
    56401 tgttggacgc ggaagtgatg cttcctactg tatcttagtt gctaatccta aaaatgaact
    56461 aggtgtggaa cggatgaaaa tcatgacaga gaccaccaat ggttttgtac taagcgaaaa
    56521 agatctggaa ttacgtggtc ctggtgaagt atttggcttc cgtcaatctg gtctgcctca
    56581 atttgcgatt gctgacttgg tgacggatgg aaatgttttg gaggtagcca gagaagaggc
    56641 tgcagccctt tggcaaataa aggattggca gatgcttcct gagtatcagc ctttagcgca
    56701 aagcctccaa atagaaaatc aggataatcg ttatttcgat tagcagactg tgctatactt
    56761 tatactgatg acggaaaaag gagtggaaac aatgaaaatt gccgtagatg caatgggcgg
    56821 agatcacgca cctcaagcaa ttgtagaagg cgtggcttta gcgcagcaag attttccaga
    56881 agtagaattc ttactttacg gaaaagaagc agaaatcaag aaatacttaa caaatgaaaa
    56941 aaacatcacg attatccata cagacgaaaa aatcaatagt gatgatgagc cagtaaaagc
    57001 aattcgacga aaaaagactg catcaatggt ccttgctgca caagcagtga aaaacggtga
    57061 agcagatgct gtattttcag cagggaatac aggcgcgcta ctagcagcag ggttgttcat
    57121 cgtaggacgt atcaaaaata tcgaacgccc tggcttgatg tctaccttgc cagtagtagg
    57181 gaaagaaggt gccggtttcg atatgctgga tcttggcgct aacgcagaaa acaaaccaga
    57241 acatttgttg caatacggta ttttaggttc tttttatgca cgtaaagtcc gaggtatcgg
    57301 acgtcctcgt gtcgcactct taaacaacgg aacagaagca acaaaaggta gtgaagtgac
    57361 gaaaaaagcc tatgaactcc ttcagaatga aacaagcttg aattttattg gaaacgtaga
    57421 agctcgtgag ctactcaatg gtgtggctga tgtagtggtc acagatggat ttacaggcaa
    57481 cgctgttttg aaatctattg aaggaacagc aatgaatatg atgaatctat taaaatctgc
    57541 tattctaaat gaagggatca aaggaaaaat gggcgctatg cttttaaaag acggcttacg
    57601 ttctttgaaa gcagaaatgg attattccaa acatggcggt gccgttttgt ttggcttgaa
    57661 agcaccagtc attaaaactc atggagcaac aggccccgat gctgttcgct atacgatccg
    57721 ccaaatccac acaatgcttg agacagatgt agttggacaa ttagtcgaac aatttgaaaa
    57781 aagcgaagaa tagtatttgg atatctgaag cgatccgttc cattgaaaaa aaggtggaca
    57841 ttcctgaaaa atgccagtaa aattagccat ggtgtaggta attgacaagt gtatgattct
    57901 tggaggtgaa aaagttgact cgcgaagaag tatttaacaa agtagcgaaa attatttcaa
    57961 atcattttga gatagatacc gataaagtga cggatgaatt gaacatcaaa gatgatttaa
    58021 aagctgattc aattagtatt atggaattcg ttttagagct tgaagatgaa ttcggtacgg
    58081 aaatttcaga tgaagacgct gaacaaattg aaacagtcgg tggcgcagta gattatatca
    58141 gcagccatct taaataattt caaataaaag caaagaagga taaaaagctg catgcagctt
    58201 tttatccttc tttttttaat ctttttgaca cgtaaaagtc atttttctga taattctggc
    58261 gataaacaga aattatgttg caaagtaaag cggttttcta tataattatt aataattcat
    58321 tacacaaaga taagaataac ctttgttata aaacgattta ttctgtgtaa tgtccttttt
    58381 tattaagaaa aacttccatt taggaagcag agaggggtat tcgattgtcc gataaccaat
    58441 tattagaagt tcagaaccta catacaggat tccgactcaa agatgactat tacgatgcag
    58501 tagatgacgt ttcatttact ttagacaaaa acgagatttt agcaatcgtt ggggaatctg
    58561 ggtgcgggaa aagtaccttg gctactacga ttatgggatt acttgatcct aataacacaa
    58621 aaattacagg tgagatttta tataacgatc tgaatttaat cgacctgaac gaaacgctct
    58681 ataataaaat ccgcggaaat gatatcggaa tgattttcca agatccgttg tctgcattaa
    58741 atcctctcat gagaatcgaa gaccagatca aagaaggact ttcctatcac acaaagatga
    58801 atgcagaaca gcgtcaagct cgtgcactag aattgctaga acaagtaggg attcctaatc
    58861 ctgcgagagt tggacgccaa tatccccatg aactatcagg cggtatgaga caacgtgtca
    58921 tcatcgcaat cgcaatcgcc tgcaaacctc caatcgtcat tgcagatgaa ccgacgacag
    58981 ccctagatgt aaccatccaa gcacagattc ttgatttact gaaagacctt caggaagaaa
    59041 caaaaacagg gatcatcttg atcactcatg acttaggagt cgtagcagaa atggctgatc
    59101 gagtggcagt gatgtatggc ggacagttcg ttgaagtagc aggtgtaaaa gaactgtttg
    59161 atcatcctaa gcatccttat acacgctctt tactgaactc tataccacaa gaaggaaatc
    59221 atgatgcaga actccatgtg atcgaaggtg tcgttccttc tctgaaaaac atgcctcgta
    59281 aaggttgtcg gtttgcacca cgtattccat ggataccagc aagcgatcat gaagaagagc
    59341 ctatccttca tgaagtcgca ccgaaccact tggtacgttg ctcctgctat aagcatttcc
    59401 actttagaga cgaaaaagga gaggtgtaga tgacagaatt aatcacaatc aaagacctga
    59461 aagttcatta ccctattcgc agtggattct tcaatcgagt aacggatcat gtatatgctg
    59521 tagatggtgt ggattttatt atcgaaaaag gaaagacata tggtttagtg ggagagtctg
    59581 gctctggaaa atctactacg ggaaaagccg ttgtgggatt agaaaaggta acagccggac
    59641 aaatcatgta tgaaggaaaa gatgtaacga agcgaagcaa ccgcaaaaaa atgggttata
    59701 acaaggatgt gcagatgatc ttccaagatt caatgtccag tttgaatcct aaaaagcgag
    59761 tgttggatat cattgctgaa cccatccgaa attttgaacg gttaagcgat caagaagaaa
    59821 agaaaaaggt aaaaggactg ctagatatcg ttgggatgcc ggaagatgcg ctatataaat
    59881 atcctcatga attttcaggc ggacaacgtc aacgtctagg agtagcccgt gctgttgcta
    59941 ccaatccaaa actgatcgta gccgatgaac ctgtatctgc tctggatcta tctgttcaag
    60001 cgcaagtatt gaatttcatg aaacgaatcc agcaagaata cggcctcagc tatttattca
    60061 tttcacatga tttaggtgta gtaaaacaca tgtgcgacaa tatcgcaatt atgtacaaag
    60121 gtcgatttgt agaaatcggt acaagagaag acatttataa tgacccgcga catatctata
    60181 cgaaacgtct gctttcagct attccgcaaa tcgatgtaga aaatagggaa agccacaaag
    60241 aaaatcgacg aagagtagaa caagagtata tccaaaacca aaaagaatac tatgatgcga
    60301 ctggtcgagt ctacgatttg cgtacgatca caactacaca caaagtggcg ttgaaagatg
    60361 gaggtgcaag ctaatgtgga aaacgattct gcgacgtgtt ttattgatga tcccgcaagt
    60421 tattatttta agtgttctga tcttcttatt agcccaagcg atgccggggg atccatttac
    60481 cggtttgatc aatccaaatc aggatccggc agtgatcgaa cagatgcgac aagcagctgg
    60541 cttgaatgac ccatggtatg tccagtactt ccgttggatc ggaaatgctt tgcaaggcga
    60601 ttttggtcaa agtttcttat acaaacgctc tgttgctgac ttgatcggcg aacggatcat
    60661 caacacttta tatctatcga tcttgacagt tgtccttact tatttgattg ctgtgcctct
    60721 ggggatgctt gctggccggt atcaaaattc aatcttggat aagattgtcg taatctacaa
    60781 cttctttagt tttgctgttc ctttatttat cttcggcttg atcatgctat ttgtttttgg
    60841 ttatcgttta ggctggttcc caacaagtgg atcacaaaca ctaggtttgc aaggtggatt
    60901 tatcactcaa tggatagacc gtttgaaata tattctgtta ccatcaatta cccaagcatt
    60961 tttggcgact gccgtcacaa tccaatatct gcgaagtgaa gtaatcgatt cgaaatcgct
    61021 cgattttgtc agaacagccc gttccaaagg ggtaccgacg aataaagtat tcagtcgaca
    61081 tattttccga aatgcagcgt tgccgatggc ttctcaaatg gggtatgaaa tcacttcgtt
    61141 gattgctggt tctgtagtta tcgaaaagat ttttggttat ccgggagtcg gaaaactatt
    61201 tattgattcc atcggccaac gggactatac cgtgatcaca tccttagtat tgattttagg
    61261 aatcgcgacg ctagtgggga cattactttc agatatcatc atgagtatcg ttgacccgcg
    61321 tattcggatt caataaaacc aatcagaaag gagaatggat cgatgagtga aaaaaacaat
    61381 acagcagttc aagaaagtat tcctcctatg gggatacgaa tgattgctcg agaatttaaa
    61441 aaagataaaa ttgctatttt ttcattaggt ttgctagtgg ttttattatt agtgatcttt
    61501 atcggtgcga tgctgaccga tcaagacaaa gtgatgtatg ttagtatctt cgacaaatac
    61561 gctgcaccag gaacagtttc gacacaagga caaaagttca ttctgggagc agatgaaggc
    61621 ggacgtgatg tattaggaca attgatcata ggtgctagaa actctgttac gatcggattt
    61681 gcgatcacga tccttacttc gatcatcggg gttggattag ggatcatctc tggctactac
    61741 ggagggatca ttgacaacat cttgatgcgg atcgttgatt ttatcatgat tctaccgatc
    61801 atgctgatca ttatcgtctt cgtatcgatt atttccagat acaatgtctg gtcctttata
    61861 ttcatcatga gtgcatttta ttgggtagct aaagcccgat tattccgaag caagacatta
    61921 tctgaagcaa gaagagatta tgtcagtgcc tcaaaaacaa tgggaaccaa tgattttaaa
    61981 atcatgttcc gcgaaatcat gccgaatcta agttcattaa tcattactaa tttgacgatg
    62041 aactttgcgg caaacatcgg tatcgagaca actttgactt tcttaggttt cggcttgccg
    62101 gcaaatgtac ctagtttagg tacattgatc ggttatgcaa gtaacggaga agtcttagtg
    62161 aatcggcaat ggatctggtt acccgcatca atccttattt tagttttgat gttgagtatc
    62221 aattatgttg gacaagcatt caagcgttct gcagatgcgc gccaacggtt aggctagtat
    62281 agaagcgaag ggggaaatag gaatgaagaa aacgattttt ggatttgcag cgctgatgtc
    62341 tgctgtcgtt cttgcagcat gcgggggcgg aggtacagat acctctggaa acaactctgg
    62401 aggcaacggc aataacaaag aggaattaac ttttccaatt gcaacaaaaa ataatgatga
    62461 tgcaatcgaa gacggcgaat tagaagctgc ggtcgcaacg gacagtcagt ttaaaggatt
    62521 gttccagtgg gagttttacc aagattcata tgatgcagct tttatggctc cttctcatga
    62581 accgctattt gcaaacgatg acgatttcag aatcacagac gacggagctg caacgcttga
    62641 tctagatgaa gatacgaaaa aagcgacaat caaagtaaaa gacaacgtca aatggtcaga
    62701 tggtgaagat gtaacggcgg acgatgtgat tttcccttac gaaatcattg ggaataaaga
    62761 ttacactggt atccgttatg acgacacttt ccgtaacatc gtaggtatgg aagaatatca
    62821 tgatggaagt gccgacacaa tctccggaat caaaaaaata gacgacaaaa cagttgaaat
    62881 cgaatataaa gaagtaaacc caagcatgct tcaatcgggt ggtggtatct ggtcatatgc
    62941 agcaccaaaa catacgttag aaggtgtagc aatcaaagat atggaatcaa gcgatcaagt
    63001 acgtaaaaat ccagtgactt ttggccctta ttacatgagt aatatcgttg caggagaatc
    63061 agtagaatac ttgccaaacg agcactactg gaatggtacg cctaaattga aaaagatcac
    63121 gatgaaatct gtaccgatgg caagtgcaac tgaagcattg aactctaaat tatatgatat
    63181 gattttccaa atgccaacag atacttacga tacctataaa gaaattgctg gctatacaaa
    63241 cttaggccgt gaacaaactt cttatactta tctaggattc aagttaggta aatggaatgc
    63301 agatacaaag agtgtggaat acaatccaga ttcaaaaatg gctgataaat cattacgtca
    63361 agcaatgggc tatgcattag ataataatgc agtaggtgaa cgtttctatg caggtttgag
    63421 aagcaatgcg acttcattga ttcctccagt attccagtca taccatgatg atgagatgaa
    63481 aggattcaca caagatctag acaaagcgaa aaaactatta gatgatgctg gctacaaaga
    63541 tgtggatgac gatggtttaa gagaagacaa agatggaaat aaactaacaa tcaactttgc
    63601 ttcgatgtcc ggtggggaaa cagcgcaacc attggcagat tactatatcc aacaatggaa
    63661 agaaattggt ttggatgtcc aatacacaac aggtcgtctg atcgaattca attctttcta
    63721 tgataaatta gaaaacgatg atcctgaaat tgatgtttac caagctgctt ggaatacagg
    63781 aactgatcca aatccaagtg gactatgggg accaaatgct gcgttcaact acactcgtta
    63841 tgaatcagaa gaaaatacaa aattgatcaa cgatatcagt tcaagcaaag catttgatga
    63901 agagtaccaa aaagaagcat atcaaaaatg gcaacaatat gcatttgaag aagcatttgc
    63961 gattccaacg ttgttccgta atgaagtatt gccagtcaac gaccgtgtca aagactggga
    64021 ttggtcttat gatgtaccaa acccatgggc aaatgtttct gttacagcag attcacgttc
    64081 ataatcacta aaaatgaccg aaaaagggcg atgtcctttt tcggtttttt gatatttttc
    64141 tgtttatttc tctaatattc aggtcaaggc gctgatttca tgacttctcc aataaacggt
    64201 gttcaaagtc cagtttctcg gtattaagtc aaatttatgc aaaaatatgg aaagccattt
    64261 tcacaaaatt ttttcttcat actcgaaact aaacgaattt ttcacaactt ctcgtcaatc
    64321 actaggatta ttaaagcttt acttaccttt tgaccgaacc atttcaaatt tgacaaaaaa
    64381 ccagtataat aaggaagtat cgaaaaaata tccataaaag gaatgtggaa aatggacaac
    64441 cagctgacaa aagaactaaa agaaaactat aacatcgttt ttcacgatct aaatttgctt
    64501 gaacaagctt ttacccattc atcctatgtg aatgagcatc gcaatctgca attatcggat
    64561 aatgagcgac ttgaattttt aggagatgcc gttttagaac tgatggtttc tcagtattta
    64621 ttccgtttat atcctcattt gccagaagga aaattgacaa aaacacgagc tgcgatcgtt
    64681 cgcgaagaca gcttgtcgaa atttgccaaa gaatgtcact ttgatcaata tgttttgttg
    64741 ggcaagggag aagagaattc aggaggacgt acgcgaccag cattgctttg cgacctattc
    64801 gaagcttttt taggcgcgtt atatcttgac cagggattcg acacgaccca tgcattcatc
    64861 gaaaaagtga tttttcctaa agtcaaagca ggtgcttttt cacatgagat ggatcataaa
    64921 acaaaactac aagaagtctt gcaaaaatca ggtgatgtat caatcgaata ccgattgatc
    64981 aatgaagaag gtccagctca tgaacgagta ttttggatcg aagtttatgt agatgatcaa
    65041 ttgattggca ctggacaagg gaaatcgaaa aaattagcag aacaagctgc ggcggaaaat
    65101 gcattggcag cactgtaaaa gtaagtgagg gaaagctttg tatttgaaac gaattgaaat
    65161 agccggtttt aaatcatttg cagacaagac agtcattgat tttgaaaata gcgtcacagc
    65221 agtggttgga ccaaatggca gcggaaaaag caatattaca gaggctatcc gctgggtatt
    65281 aggagaacaa tctgctaaaa gtctgcgagg cggaaaaatg ccggatatca tctttgccgg
    65341 ttccgatacc cgtaagcagc tgaatattgc agaagtcaca gtgattttag acaatagtga
    65401 tcattatctg ccattggagt acaatgagat cagtgtaacc cgccgttatc gacggactgg
    65461 ggaaagcgag tttttcatca ataaacaaag ctgcagatta aaagatatcc aagaattgtt
    65521 cttagattct ggattaggaa aagaatcgtt ctcaatcatt tctcaaggaa aagtagaagc
    65581 gattttcagt agtaaaccgg aagaccgtcg tgggatcttt gaagaagcag ctggtgtctt
    65641 gaaatacaag cagcggaaaa agaaagcaga acagaagctt tttgaaacag aagacaacct
    65701 cagccgcgtc caagacatca tccacgaatt ggaagaacag ttaactcctt tggccgccca
    65761 gagtgaggca gcaaaggagt ttttacggct aaaagaaaca ctgactcaaa ccgatgtctc
    65821 tttgatggtt gctgaaatca agacagcaaa aaaagattgg gacaacaaac aagcacagct
    65881 tgcgaaattc aatctagaat taggcaaact atctgagtcg atccaagaac aagaatccat
    65941 tttggcgaag cagcgtaaag aaaatgcgca agccgatcgt ctgatcgaaa aaaatcagca
    66001 agtattatta gatctttcgg aaaaactgaa gcagacagaa ggacaaaaag atgttttgca
    66061 ggagcggaca aagcatacac aaaaaagctc gcaagaatat caaacttcat tagcagaagc
    66121 acaaaaaaag gttaaacatt ttgaaaagct tcaagaaagc ttgatgaaag cagcagcaga
    66181 aaaagaaaca gagatccaaa aagctgaagc aaatctcata aaaacacagc aagaattaga
    66241 aaaataccaa aaatcaacga aagaattatt ggcagaatta agagatcaat atgttgattt
    66301 gatgcaagaa caagcagctg taggaaacga actgaagtat ctagaacgtc aatatataca
    66361 agaaacagca aaaagcaagc agacgttagc caagcaatcg gaagtagaag catcagtaga
    66421 ccgattgatc ttacaaaaag aagaattgac acaaaagcag gcgcagctaa aatcatcttt
    66481 aactgaaaca aaagagaagt tagaaatgat ccaacaaaac gggaaaaagt tccaagaagc
    66541 attagcaaaa gaacagccta aaatgtatca attaatgaat caagtccagc agctacgtgc
    66601 tcgtaagaaa agccttcaag aaatccaaga aaactatttt ggtttttacc aaggggttcg
    66661 attggtcttg cagcataaac agcagctttc gggtattgtc ggagcagtgg ctgaactgat
    66721 cgatgttcct gcagatttca cgttagctat cgaagcagct ttaggtgggg cagcccagca
    66781 tgtcatcgtt gaaaatgaaa aagatgctcg gcaagccatc acgtatttga aacagcaaag
    66841 aggaggaaga gcaacattcc ttccactgac gacaatcaaa ccaagacaat taccggctca
    66901 tatattgaca caagcagcag ctgtagaagg gtttataggg attgccagtg aacaagtcag
    66961 ttatcccgat caaatccaaa ctgtggttca aaacctgcta ggaacgatcc ttttagccaa
    67021 agacttaact agtgccaatg caatcgcgca aacgatccgc tatcaatatc gagtggtttc
    67081 cttagaaggt gatgtgatga atgccggagg atccatgaca ggtggagcga ataaacgagg
    67141 aaaccaaggc agtttgtttg tacaaaatca agaattgaaa cagttgacta gtgaatttga
    67201 agaagcagat aaacaactcc aagcacaaga aaaaaaagtt caggagctgc aacaagaaac
    67261 agctcgttta gccgaagaac aagaagtttt gcgtacacga ggcgaacaat tacgttttga
    67321 agaacaagaa gcgacaaatc agctacaaaa catcataaat gaacttgaac gttttgaaaa
    67381 agaaaagcaa atctcaactt ttgagacacg tgaactgcag cagtttatcg aagattacga
    67441 aaagcaaacg aacgaattga aagacaaaca aacagatctt gaatcgcaac gacaaaaaat
    67501 cgacgaagaa atcaaatcgt taagtcaaga aagcgaccag atggaagcca gaagagcaca
    67561 agtacaaagt caaaaagcac aagaacaagc agatcttgct gtcttgaaag agcagtttaa
    67621 tcatctgcag atccagctcc gcggtgcccg agtccaaaaa gcagaggcaa ccgaacgtca
    67681 agaagcgata gaaaagcagt tggcgacatt gacagcagac ttttctgatc atgaagtcac
    67741 agaagaaagt ttggaaaaac aaattaacga attatctgct cagcgagaaa cattaaaagc
    67801 cgagttggca aaagccaaag agcagcgaga tagaaggcaa aaggagatcg ataagcttga
    67861 agcagtcttg gcagagcgta atcgtgagca aaaagcacga ctgtcggaac aatccaaatt
    67921 agaagtccaa aaagaccgag ctgaaatgat tttagataat catttgacct atctgcagtc
    67981 agaatatcag ctgacatttg agaaagcttc ccaagactat caagaaacaa ccgatatcga
    68041 agacagtaga acaaaggttt catccttaaa agaacagatt gaaaaactgg gaccagtaaa
    68101 cttaaattca atcgaacaat acgaacaagt cagtgaaaga catacattct tagcaacaca
    68161 gcgagatgat ctgttagcag cgaaaaacca attgtttgaa acgatggatg agatggatga
    68221 tgaagtgcgg acaagattca aagaagtatt tgaagctatc cgtcaagaat tcaaaattgt
    68281 ctttccaaat atgtttggcg gcggtaaagc tgaattagta ctgacggaac caactgattt
    68341 gctgaaaaca ggtattgaga ttgaagtaca acctcctggc aaaaaactgc aaagtctaag
    68401 tttgctttct ggaggagaac gagcacttac agccatcgcg ttgctctttt ccattatccg
    68461 tgtctgtcct gttccgtttt gtatcttaga tgaggtagaa gcagcgttag atgaagccaa
    68521 cgtgaaacgt tttggtcgtt acttgagcga tttccaagat gacacacaat ttatcgtagt
    68581 cacacaccgc aaaggaacga tggtcgcagc agatgtactg tacggagtga cgatgcagga
    68641 atccggtgta tcaaaaatcg tttctgtacg gatggaagat atcaatgaag aggcgaaaat
    68701 caacgaaacg aaagtgtagg aacgaaaatg atcaaattag tagcaatcga tttggacggt
    68761 acattattaa atgaacaaaa gctgatttca gatgagaata aacaagcatt agcacaagca
    68821 aaacagcaag gggtcaagat cgttctatgt acaggacgcc ccttagctgc gatggcgcat
    68881 tatctgcaag aattaggact ggtagatgaa ggtgactaca gcatcacttt caacggcggt
    68941 ttggtacaaa aaaatgatac tggtgaaatc atggaaaaga aagtgatgga agtatcagat
    69001 atccaacgct tatacaaact ggctcagcaa ttggatctgc cactagatgt tttgtctgac
    69061 aatgtggttt tacagctgcc tagtgcccca aggaagcaat ccttgtacaa tgtgttgaat
    69121 aagctgctgc aattccaacc agcggatata agcgatatta cagatgaatt tgtgcttaat
    69181 aaggcagtaa tcgcttatga ccaagaagaa ttagatccta aaatcaaaga aataccagca
    69241 gaattccatg aaatgtatga gatcatcaaa acaagaagta tgcttttgga atttatgcca
    69301 aaaggtgtta caaaagctta tggtatttct ttattggcaa aagatcttgg tttgaaacaa
    69361 gaagaaatca tggcgatcgg tgatgaggaa aatgatttac cgatgatcca atatgctgga
    69421 ctaggcgtag cgatggagaa tgctgtgcct ttcgtcaaag aagcagcaga tttcgtgaca
    69481 gccagcaatg aagaaaatgg cgtagccaaa gtgatccaaa aatttgtatt agagtagggg
    69541 gagtcaaatg ggattttttg ataaaatcaa gcgtgctttt actggcgaag agaaaacaga
    69601 agaagttgaa gtacaggaga agtacgacaa gggtttagaa aagacgcgta aaacatttgg
    69661 tgaacggatg aatgagttgt ttgccaattt tcgaacagtc gatgaagact tttttgaaga
    69721 attagaagaa acacttatcg gtgcagatgt aggttttgaa acagcgatac gaatcaccga
    69781 agcattacgt caagaagtga aactcagaaa tgcgaaaaaa tcggcagaag tccaaaatgc
    69841 gatcatcgag aaacttgtgg atctctatga agcggaagga atcaatgaag taaatgaact
    69901 aaatatccaa gaagacggac taacagttat tttgtttgtc ggtgttaatg gtgtagggaa
    69961 aacaacaagt attggtaaac ttgcccatca gttcaaaaac gaaggtaaaa aagtattgat
    70021 ggcagcagca gataccttcc gcgctggagc aatcgaccag ttagttgtct ggggcgaacg
    70081 cgctggtgtt gaagttgttc gtggcaatgc aggaggcgat ccagcagctg tcgtattcga
    70141 tgctttggaa agagcaaaga cagagcaggc agatgtttta ctagttgata ctgcaggccg
    70201 actgcaaaat aaagtgaact tgatgaacga attagaaaaa ataaaacgag taatccagcg
    70261 ggaattacca gaagcacccc aagaaacact tcttgtatta gatgcaacca ctggtcaaaa
    70321 cgcgatggtt caagcaaaac aattcaaaga aacaacagat gtgaccggtc ttgttttgac
    70381 aaaattagat ggtacagcaa agggcggtat cgtacttgct atccgtaatg aattgcattt
    70441 accagtgaaa ttggtcggtc ttggtgaagg aatcgatgac ttggagccgt ttgatccaaa
    70501 tgattttgtc gttggattgt tcaaaggatt actaaaagaa gaataaccca tgtctaaaaa
    70561 gcaggagctg tgacaaaagt tgcagctcct tgtttgaatg attgttttta acatagctgt
    70621 gtttttgatg ccttcatttt tatacttatt tgtaagcggt tctcaaacaa tttcgttctt
    70681 tttcttagac tttttgatta taattagatt catatgaatt ggaggtcact taatgatgaa
    70741 ttttaagcaa ttattattgc atgtcaatgc gcgccctttt atcgaccaag ctcgatttgg
    70801 tatagaacgg gaaggacagc gggttgatct tgcaggaaat ctagcaaaaa ccgatcatcc
    70861 agcaatcttt ggcgatcgat cctatcaccc ctatatccaa acagatttta gcgaaacaca
    70921 aacagagatg atcacccctg ttaccgattc tattcccgaa ttatttcagt atctcgctgc
    70981 tgtttatgat gtgactgctc gttctatacc gaaagaagag atgatctggc cattaagtat
    71041 gccacctgcc ttaccggaaa aagacgaaga gatcattatt gcaaaattaa aaaatttcga
    71101 agatgtcttg tatcgacgtt atttagcaaa agaatacggg aagcgaaaac agatggtaag
    71161 cggtattcat ttcaattttg aatttggcga tgagttgcta agaacattgt tcagccatca
    71221 ggaagaattt caagattttt ccgaattcaa aacagaactt tatttgaaaa cagcgagaaa
    71281 ctttatgcgc tatcgctgga tgatcactta tttattcggt gcttcaccaa tgagtgagaa
    71341 gaactacttt ttagatgaat cacatccgca agaacctgtt cgcagtattc gcaacagtgc
    71401 gctgggctat acgaatcatc caaatgtgaa agtttcctat gcttctatga aacagtattt
    71461 agcagatatc gagcgaatga tcgaagaagg gaaactttcg gaggagaaag aattttatac
    71521 accgcttcgt ttccgaggcg gaaagaaagt cgcagattta gcaacaacag gtgttcgtta
    71581 tattgaattg cggaatatcg atttgaatcc ttatgcaaga ttgggtatca atccagagca
    71641 agttcggttc ttacaattat tcctgatgta catgttatgg acagaagaaa aagaagactg
    71701 tgaccaatgg gtagcagaag gtacgactcg aaataacaaa gtagcactag aacaaccatc
    71761 agatcaaaca gaatttcatc aagaaggtag agaaattctt gaaggaatga agcaaatgct
    71821 ggttgaattg gattggttgg attctcttta tttagtagag gaagcattga ctcaaatgga
    71881 tcatcctgaa caaacgttag cagcgaaact ctatcaagaa gcacagctat cgagtcagca
    71941 agaagttgct gtggcattgg gacatcaata ttataaagaa agccatgaac gtccctatca
    72001 gttggccggt tttcgcgaaa tggaactttc tactcagata tttatgttcg atgccatcca
    72061 aaaaggtgtc caagtcaaag tattagatga gtcggatcaa tttttgcgtc tgcaattcca
    72121 agaccatgta gaatatgtga aaaatgcaaa catgacaagt aaggacagct atatcgtccc
    72181 acttatcatg gaaaacaaaa cagtaacgaa aaaagtctta aaagaagctg ggttccgggt
    72241 accaggaggc gcagaatttt catccatgga agaagcggta aaagcttatc cgagatttgc
    72301 cgagcaggca tttgtgatca aacctaaatc aaccaattac gggttaggta tcacgatttt
    72361 caaggaagga gctagtctgg aagattatca agcaggttta gccattgctt ttcgtgaaga
    72421 cagttcggtt ttagtagaag aatttatgcc gggaacggaa tatcgtttct ttgtgatcga
    72481 cggagaagtc caagccatca tgttgcgagt ccctgctaat gttattggtg acagtatccg
    72541 aacagtgaaa gaacttgttg aagaaaaaaa tagtgaccct ttgcgtggaa cgaatcatcg
    72601 tgcaccttta gaattgatcc aattaggtga attagaacaa ttgatgttga aagaacaagg
    72661 gttgacgatc gaatcagttc cccaagccaa tcaaattgtt tatctaaggg agaactcaaa
    72721 tatcagtaca ggtggtgatt cgatcgatat gactgatgaa ttttctgaag cttacaaaaa
    72781 aatcgccgtt tctgcggtag aagcactagg agctaagatt agtggtatcg atttgattat
    72841 accagataaa gaaatcgatc ctacaactga taaaaaagca tatgggatca tcgaagcaaa
    72901 tttcaatcca gccatgcata tgcatgttta tccttttgca ggaaaaggca gaagattgac
    72961 gatgaatgta ttgaaattgt tatatcctga agtattttaa aagaaaaagc ttttgacaga
    73021 ttgtcc
//
LOCUS       DAZKNV010000008        69784 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000008 DAZKNV010000000
VERSION     DAZKNV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 69784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.008"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(6..122)
                     /locus_tag="ACG8M1_000567"
     CDS             complement(6..122)
                     /locus_tag="ACG8M1_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFQ0421308.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(195..1151)
                     /locus_tag="ACG8M1_000568"
     CDS             complement(195..1151)
                     /locus_tag="ACG8M1_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0421309.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1322..1690
                     /locus_tag="ACG8M1_000569"
     CDS             1322..1690
                     /locus_tag="ACG8M1_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFQ0421310.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1860..2291
                     /gene="mraZ"
                     /locus_tag="ACG8M1_000570"
     CDS             1860..2291
                     /gene="mraZ"
                     /locus_tag="ACG8M1_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFQ0421311.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            2312..3271
                     /gene="rsmH"
                     /locus_tag="ACG8M1_000571"
     CDS             2312..3271
                     /gene="rsmH"
                     /locus_tag="ACG8M1_000571"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFQ0421312.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            3276..3677
                     /gene="ftsL"
                     /locus_tag="ACG8M1_000572"
     CDS             3276..3677
                     /gene="ftsL"
                     /locus_tag="ACG8M1_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFQ0421313.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRRVK"
     gene            3678..5870
                     /locus_tag="ACG8M1_000573"
     CDS             3678..5870
                     /locus_tag="ACG8M1_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFQ0421314.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5896..6858
                     /gene="mraY"
                     /locus_tag="ACG8M1_000574"
     CDS             5896..6858
                     /gene="mraY"
                     /locus_tag="ACG8M1_000574"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFQ0421315.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6872..8233
                     /gene="murD"
                     /locus_tag="ACG8M1_000575"
     CDS             6872..8233
                     /gene="murD"
                     /locus_tag="ACG8M1_000575"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFQ0421316.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            8259..9347
                     /gene="murG"
                     /locus_tag="ACG8M1_000576"
     CDS             8259..9347
                     /gene="murG"
                     /locus_tag="ACG8M1_000576"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFQ0421317.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            9362..10582
                     /locus_tag="ACG8M1_000577"
     CDS             9362..10582
                     /locus_tag="ACG8M1_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFQ0421318.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10738..12063
                     /gene="ftsA"
                     /locus_tag="ACG8M1_000578"
     CDS             10738..12063
                     /gene="ftsA"
                     /locus_tag="ACG8M1_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFQ0421319.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            12086..13327
                     /gene="ftsZ"
                     /locus_tag="ACG8M1_000579"
     CDS             12086..13327
                     /gene="ftsZ"
                     /locus_tag="ACG8M1_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFQ0421320.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            13344..14021
                     /locus_tag="ACG8M1_000580"
     CDS             13344..14021
                     /locus_tag="ACG8M1_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFQ0421321.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            14035..14634
                     /locus_tag="ACG8M1_000581"
     CDS             14035..14634
                     /locus_tag="ACG8M1_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFQ0421322.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14715..14936
                     /locus_tag="ACG8M1_000582"
     CDS             14715..14936
                     /locus_tag="ACG8M1_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFQ0421323.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            14985..15767
                     /locus_tag="ACG8M1_000583"
     CDS             14985..15767
                     /locus_tag="ACG8M1_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFQ0421324.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15788..16495
                     /locus_tag="ACG8M1_000584"
     CDS             15788..16495
                     /locus_tag="ACG8M1_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFQ0421325.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16757..19555
                     /gene="ileS"
                     /locus_tag="ACG8M1_000585"
     CDS             16757..19555
                     /gene="ileS"
                     /locus_tag="ACG8M1_000585"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFQ0421326.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19604..21130)
                     /gene="zwf"
                     /locus_tag="ACG8M1_000586"
     CDS             complement(19604..21130)
                     /gene="zwf"
                     /locus_tag="ACG8M1_000586"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFQ0421327.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(21145..21792)
                     /locus_tag="ACG8M1_000587"
     CDS             complement(21145..21792)
                     /locus_tag="ACG8M1_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFQ0421328.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(21976..22305)
                     /locus_tag="ACG8M1_000588"
     CDS             complement(21976..22305)
                     /locus_tag="ACG8M1_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFQ0421329.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22482..23210
                     /gene="sfsA"
                     /locus_tag="ACG8M1_000589"
     CDS             22482..23210
                     /gene="sfsA"
                     /locus_tag="ACG8M1_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFQ0421330.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            23226..24239
                     /locus_tag="ACG8M1_000590"
     CDS             23226..24239
                     /locus_tag="ACG8M1_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0421331.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            24239..25516
                     /locus_tag="ACG8M1_000591"
     CDS             24239..25516
                     /locus_tag="ACG8M1_000591"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0421332.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25579..28281
                     /locus_tag="ACG8M1_000592"
     CDS             25579..28281
                     /locus_tag="ACG8M1_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0421333.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28433..28750
                     /locus_tag="ACG8M1_000593"
     CDS             28433..28750
                     /locus_tag="ACG8M1_000593"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0421334.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28780..29100
                     /locus_tag="ACG8M1_000594"
     CDS             28780..29100
                     /locus_tag="ACG8M1_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0421335.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            29208..30668
                     /locus_tag="ACG8M1_000595"
     CDS             29208..30668
                     /locus_tag="ACG8M1_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0421336.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30736..30957
                     /locus_tag="ACG8M1_000596"
     CDS             30736..30957
                     /locus_tag="ACG8M1_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421337.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            30988..31170
                     /locus_tag="ACG8M1_000597"
     CDS             30988..31170
                     /locus_tag="ACG8M1_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFQ0421338.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            31170..31583
                     /locus_tag="ACG8M1_000598"
     CDS             31170..31583
                     /locus_tag="ACG8M1_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFQ0421339.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31706..32887
                     /locus_tag="ACG8M1_000599"
     CDS             31706..32887
                     /locus_tag="ACG8M1_000599"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0421340.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(32958..33122)
                     /locus_tag="ACG8M1_000600"
     CDS             complement(32958..33122)
                     /locus_tag="ACG8M1_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421341.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            33276..33349
                     /locus_tag="ACG8M1_000601"
     tRNA            33276..33349
                     /locus_tag="ACG8M1_000601"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33310..33312,aa:Arg,seq:cct)
     gene            complement(33418..34557)
                     /locus_tag="ACG8M1_000602"
     CDS             complement(33418..34557)
                     /locus_tag="ACG8M1_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0421342.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            34729..34863
                     /locus_tag="ACG8M1_000603"
     CDS             34729..34863
                     /locus_tag="ACG8M1_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421343.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(34856..35491)
                     /locus_tag="ACG8M1_000604"
     CDS             complement(34856..35491)
                     /locus_tag="ACG8M1_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421344.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(35604..36239)
                     /locus_tag="ACG8M1_000605"
     CDS             complement(35604..36239)
                     /locus_tag="ACG8M1_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFQ0421345.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPSTEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(36273..36734)
                     /locus_tag="ACG8M1_000606"
     CDS             complement(36273..36734)
                     /locus_tag="ACG8M1_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFQ0421346.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(36864..37295)
                     /locus_tag="ACG8M1_000607"
     CDS             complement(36864..37295)
                     /locus_tag="ACG8M1_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFQ0421347.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(37313..37633)
                     /locus_tag="ACG8M1_000608"
     CDS             complement(37313..37633)
                     /locus_tag="ACG8M1_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0421348.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            37932..38708
                     /locus_tag="ACG8M1_000609"
     CDS             37932..38708
                     /locus_tag="ACG8M1_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFQ0421349.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            38723..38926
                     /locus_tag="ACG8M1_000610"
     CDS             38723..38926
                     /locus_tag="ACG8M1_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421350.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            38942..39280
                     /locus_tag="ACG8M1_000611"
     CDS             38942..39280
                     /locus_tag="ACG8M1_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFQ0421351.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            39267..39446
                     /locus_tag="ACG8M1_000612"
     CDS             39267..39446
                     /locus_tag="ACG8M1_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421352.1"
                     /translation="MGKFNRALVFSAPLIIYALELWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(39489..39959)
                     /locus_tag="ACG8M1_000613"
     CDS             complement(39489..39959)
                     /locus_tag="ACG8M1_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421353.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            40046..40744
                     /locus_tag="ACG8M1_000614"
     CDS             40046..40744
                     /locus_tag="ACG8M1_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFQ0421354.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            40922..41263
                     /locus_tag="ACG8M1_000615"
     CDS             40922..41263
                     /locus_tag="ACG8M1_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421355.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            41256..41927
                     /locus_tag="ACG8M1_000616"
     CDS             41256..41927
                     /locus_tag="ACG8M1_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFQ0421356.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            41933..42619
                     /locus_tag="ACG8M1_000617"
     CDS             41933..42619
                     /locus_tag="ACG8M1_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFQ0421357.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            42622..43371
                     /locus_tag="ACG8M1_000618"
     CDS             42622..43371
                     /locus_tag="ACG8M1_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421358.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            43383..43652
                     /locus_tag="ACG8M1_000619"
     CDS             43383..43652
                     /locus_tag="ACG8M1_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421359.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            43657..43821
                     /locus_tag="ACG8M1_000620"
     CDS             43657..43821
                     /locus_tag="ACG8M1_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421360.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            43814..44116
                     /locus_tag="ACG8M1_000621"
     CDS             43814..44116
                     /locus_tag="ACG8M1_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421361.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            44113..44274
                     /locus_tag="ACG8M1_000622"
     CDS             44113..44274
                     /locus_tag="ACG8M1_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFQ0421362.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            44271..44576
                     /locus_tag="ACG8M1_000623"
     CDS             44271..44576
                     /locus_tag="ACG8M1_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421363.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            44576..44932
                     /locus_tag="ACG8M1_000624"
     CDS             44576..44932
                     /locus_tag="ACG8M1_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFQ0421364.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            44892..45137
                     /locus_tag="ACG8M1_000625"
     CDS             44892..45137
                     /locus_tag="ACG8M1_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421365.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            45134..45553
                     /locus_tag="ACG8M1_000626"
     CDS             45134..45553
                     /locus_tag="ACG8M1_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFQ0421366.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            45550..46107
                     /locus_tag="ACG8M1_000627"
     CDS             45550..46107
                     /locus_tag="ACG8M1_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFQ0421367.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            46104..46400
                     /locus_tag="ACG8M1_000628"
     CDS             46104..46400
                     /locus_tag="ACG8M1_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421368.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            46477..46890
                     /locus_tag="ACG8M1_000629"
     CDS             46477..46890
                     /locus_tag="ACG8M1_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFQ0421369.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            47199..47351
                     /locus_tag="ACG8M1_000630"
     CDS             47199..47351
                     /locus_tag="ACG8M1_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421370.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(47348..47623)
                     /locus_tag="ACG8M1_000631"
     CDS             complement(47348..47623)
                     /locus_tag="ACG8M1_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421371.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            48481..48648
                     /locus_tag="ACG8M1_000632"
     CDS             48481..48648
                     /locus_tag="ACG8M1_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFQ0421372.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            48674..49018
                     /locus_tag="ACG8M1_000633"
     CDS             48674..49018
                     /locus_tag="ACG8M1_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFQ0421373.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            49023..49304
                     /locus_tag="ACG8M1_000634"
     CDS             49023..49304
                     /locus_tag="ACG8M1_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421374.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            49407..49721
                     /locus_tag="ACG8M1_000635"
     CDS             49407..49721
                     /locus_tag="ACG8M1_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFQ0421375.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            49699..51393
                     /locus_tag="ACG8M1_000636"
     CDS             49699..51393
                     /locus_tag="ACG8M1_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFQ0421376.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            51413..52591
                     /locus_tag="ACG8M1_000637"
     CDS             51413..52591
                     /locus_tag="ACG8M1_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0421377.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            52554..53240
                     /locus_tag="ACG8M1_000638"
     CDS             52554..53240
                     /locus_tag="ACG8M1_000638"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFQ0421378.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            53240..54400
                     /locus_tag="ACG8M1_000639"
     CDS             53240..54400
                     /locus_tag="ACG8M1_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFQ0421379.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            54410..55285
                     /locus_tag="ACG8M1_000640"
     CDS             54410..55285
                     /locus_tag="ACG8M1_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421380.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            55282..55593
                     /locus_tag="ACG8M1_000641"
     CDS             55282..55593
                     /locus_tag="ACG8M1_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421381.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            55583..55936
                     /locus_tag="ACG8M1_000642"
     CDS             55583..55936
                     /locus_tag="ACG8M1_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFQ0421382.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            55926..56327
                     /locus_tag="ACG8M1_000643"
     CDS             55926..56327
                     /locus_tag="ACG8M1_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421383.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            56320..56724
                     /locus_tag="ACG8M1_000644"
     CDS             56320..56724
                     /locus_tag="ACG8M1_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421384.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            56736..57344
                     /locus_tag="ACG8M1_000645"
     CDS             56736..57344
                     /locus_tag="ACG8M1_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0421385.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            57364..57726
                     /locus_tag="ACG8M1_000646"
     CDS             57364..57726
                     /locus_tag="ACG8M1_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421386.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            57729..57911
                     /locus_tag="ACG8M1_000647"
     CDS             57729..57911
                     /locus_tag="ACG8M1_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421387.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            57928..61359
                     /locus_tag="ACG8M1_000648"
     CDS             57928..61359
                     /locus_tag="ACG8M1_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFQ0421388.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGTKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            61410..62147
                     /locus_tag="ACG8M1_000649"
     CDS             61410..62147
                     /locus_tag="ACG8M1_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0421389.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            62157..64448
                     /locus_tag="ACG8M1_000650"
     CDS             62157..64448
                     /locus_tag="ACG8M1_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFQ0421390.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFCSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            64472..66598
                     /locus_tag="ACG8M1_000651"
     CDS             64472..66598
                     /locus_tag="ACG8M1_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421391.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            66615..66764
                     /locus_tag="ACG8M1_000652"
     CDS             66615..66764
                     /locus_tag="ACG8M1_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421392.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            66761..67207
                     /locus_tag="ACG8M1_000653"
     CDS             66761..67207
                     /locus_tag="ACG8M1_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421393.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            67209..67346
                     /locus_tag="ACG8M1_000654"
     CDS             67209..67346
                     /locus_tag="ACG8M1_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFQ0421394.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            67384..67677
                     /locus_tag="ACG8M1_000655"
     CDS             67384..67677
                     /locus_tag="ACG8M1_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421395.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            67674..67898
                     /locus_tag="ACG8M1_000656"
     CDS             67674..67898
                     /locus_tag="ACG8M1_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFQ0421396.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            67895..68920
                     /locus_tag="ACG8M1_000657"
     CDS             67895..68920
                     /locus_tag="ACG8M1_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFQ0421397.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            69110..69183
                     /locus_tag="ACG8M1_000658"
     tRNA            69110..69183
                     /locus_tag="ACG8M1_000658"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:69144..69146,aa:Ile,seq:cat)
BASE COUNT        23872 a        11309 c        14392 g        20211 t
ORIGIN      
        1 tatttttaca tgacactcat tacagcagtc aatacaacag atccaatcgt taaaatcagc
       61 attgtccaaa tgacaaattt tgttacttta gcaaaagtac ttgtttgttt tttttcacgc
      121 attgttttca acctcgtcat taattagttg attcaagtgt acaatctttt ttccatttcc
      181 acaagagggc ttttttataa aaacttccct ttttttaaat aataggtagt tacgatacaa
      241 ataaataatg ttaatagaac tagccatata aaggcatcat ccctttcagc aataggtaac
      301 ttaatgttca ttccatagat actgccgacg attgtcggta tagttaaaat aatcgttaaa
      361 gaagttaaaa ttttcataat attattcaga ttattcgata cgattgctga aaaagtctga
      421 ttcatttgtt ctactagttt taattgaatg cgagaagtag tcattgcctg ctctgtttcc
      481 accaatacat cacgtaaatg atttttcaaa gcatgatttt cttggaaaag tttattttgc
      541 gctagttctt tcaatgcatc taaattagca gaagtcgctt ctctgaaata aacgaggctt
      601 ttttggatat ccatgatttg ataaagttgt ttgttttcag tggatacttg aagtttggct
      661 tccaaagtat cgcattgaga ttgaagcgta gctaaataac tgttgtaaga gagtgtgacc
      721 tgccaaatga attgaaagaa gatattgaga ttaggcgaaa tatcactttt tggaaaggtc
      781 tggctaaaga ctttctttaa aaacagtggt tcatgattcg taattgtgat aagcttcttt
      841 ttgggcgtca aaataataga gagcgggtat gtatccactt gaaaataacc gctaggactt
      901 gttttagcaa aaggatattg taacaataat aacgctggct ttgtcaactt tgattgattg
      961 aattcttctg tacgggaatt ttctgcatcg tccaatatgg aagtgatgta atctgacgga
     1021 atttcaaatt gatgtgtcag ctgatgaatc tcttcttgat taggacgttc tacacaatac
     1081 cagatcgttt ggtcagtttc ctttccggta ttacgcagtt tctcattatc taatgtaaaa
     1141 tatttgatca tgattttcct cctgttgcct gtttctttta ttataacgga tagggaattg
     1201 gaatacatgg aatgtgtttg taagatatag aatataactg cataaattta aataaaatga
     1261 aacagttgtg taaagtatat acagtatact tgaagcaacg ataaaaaagg agtttacgtt
     1321 catgggcaca ttcacaccac ttatcttgtt ttggtatatt tacccggtaa tcgttttgtt
     1381 tggttgccaa tttcttgtaa aattattttc gttaaatcgt cgttttaaaa taaaagcccc
     1441 tgatttggcg attccttttt tgtggggcgg tatgcatgca ttgtctagaa atacagggac
     1501 aatttctatc ttaccgtttt tctttatttc tgttttgcta atgggaattt gtattgctgt
     1561 tttccaagca tattattatg aagaaattat ttatccgcgt tatttcaaga tgacttggcg
     1621 tttggttttt ctgttgacaa tcgtcttgta cgctgtcttg atcattgtga acatactttc
     1681 ttacctatga aaaaaataga aaagctgtaa aaagtctttt aaaaggcttt ttgcagcttg
     1741 atttttaaaa aaatgtttat gaataaaaaa agttgttccc ggatttccca gaaaaggtgg
     1801 tagaaagtgg gggattgtgg tagactaatt ttagttagtg gaggaatggg gggctttcaa
     1861 tgttgatggg tgaattccaa cataatattg atgcaaaagg acgtttaatc gtgccctcaa
     1921 aacttcgtga agaacttggc gaaaagtttg ttctgacacg cggattggat ggctgtcttt
     1981 tcggctatcc gatgagcgaa tgggaaaatc tggaagctaa actgaacgaa atgccgttgg
     2041 ctaaaaaaga cgcacgtact tttgtgcgat tcttctattc ggctgccact gaatgcgaac
     2101 ttgataaaca aggacgaatc aatataccca gcacgttaag aaattatgca gctttgacaa
     2161 aaggttgcgt agtcatcggt gtatctaacc gaattgaaat ttgggatgag acacgatggc
     2221 aagatttttc tgcagcagca gaagagaact ttgacgaaat tgctgaaagt atgattgatt
     2281 tcggactata agaataggaa gaggctgact aatgactgaa acatttcaac actatacagt
     2341 catgttgaaa gaaacggtag atggattgaa catcaaaccg gatggcgttt atgtagactg
     2401 tacactcggc ggtgccggac atagtgaata tttattaagc caactaagtt ctaaagggca
     2461 tctgtatgcg tttgaccaag atcaaaaagc aatcgatcac gccaagctgc gtttagcttc
     2521 ttatgtcgaa caaggtatgg tcacatttat caaagcgaac ttcagagaat tagaagaacg
     2581 cttgagtgag catgtagata aggtagacgg cattttgtat gatctagggg tttcctctcc
     2641 tcagctagat gaagcagaac gtggatttag ttatcatcaa gatgcaccgt tggatatgcg
     2701 catggatcag tcagctcctt tatccgctta tcacgtaatt aatgaatatt cctaccatga
     2761 attagtaaag attttcttcc gctatggcga ggagaaattt tccaaacaaa ttgctcgtga
     2821 aatcgaacga gtacgaaaaa caaaaccaat ccaaacaact ggtgagcttg tcgaaatcat
     2881 taaacaagtc atcccagctc ccgcaagaag aaaaggcggg catcctgcaa aaagaatttt
     2941 tcaagctgtg cggattgcag taaatgacga actcggtgcc gaagaggcct ctttagaaca
     3001 ggcaatccgg ttattgaaag tcaatggaag aatcagcgta atcacattcc attcattgga
     3061 agacagaatt gtcaaaagta tgtttaaaga atatagtacg gtacaagatc taccaccggg
     3121 acttcctgtc atacctgacg aattccaacc agaactgaaa gtcattactc gtaaaccaat
     3181 ccttccttca gaggaagagc taacagaaaa caatcgatca cgcagtgcaa agttacgtat
     3241 tgcagaaaaa ataagaatga aagaggagta gaatgatggc agaattaaag aaaatgcaag
     3301 attacgaata tgatttacct gaattggtgg atcagccgga acaacaaatg cctgattctt
     3361 cttcgaatca agaaatcatt cttccacaat caccggcaaa acgattaaag cagatttctg
     3421 ctttggaaaa aattgctgtg gcaagcgtgg cgattgctat tgttgcttta tgtgttttaa
     3481 cagttatgct gcgcacaaat atcagcggag ctgaaaaaga aatcacgtca atacaaacag
     3541 aaatcaatga taaaaagcaa gaaaaaacga gtttagaaca agaaaaaaac gaactttctc
     3601 gtactgaacg gattaaacaa atcgcagaag aaaaaggatt gtctattaat gacgacaatt
     3661 taaggagagt gaagtaaatg agtcttaaaa ataaaattcg gcggtttatg gaaaagaaaa
     3721 atctaaatcc gatgaacaat cgcaaaaaag taggtatcat tttatttgct acgagtattg
     3781 gattgttctt tttatttgcc gtccgtttct cgtatatcgt tattggaggt catgttgctg
     3841 gtacctcatt agctgaaaaa acaaaacagt tgtaccaagg aagtgaagta gtaaaagcaa
     3901 aaagaggaac gatttatgat cgtaacggtg tggcgctcgc agaagatgcc tcctcttatt
     3961 caattaaagc gatactctca aaaacatata cctctgggga taaaaaactg tatgttgaag
     4021 aaaagaattt tgataaaata gcagaaatcc tgcataagaa tctttctata gacaaaaaag
     4081 atgcactgaa tattttagag gacggcgcaa aaaaagagct gtatcaagtt gaatttggta
     4141 gctatgggaa aaatatctcc caagaaacca agcaaaacat cgaagcggac atgaaaaaag
     4201 aaggtgtcgc tggtctttat tttgtcgacc atcaggctcg gatgtatcca aatggcgtct
     4261 tttcttctca ttttattgga tacgcagttc cagacaaaga tgagaatggc ttagttggta
     4321 aactaggttt ggagtctgct tacaatgata tcttgagcgg taaagatggt aagattattt
     4381 atcaaaaaga taattttcaa aatcctctgc caggtacagt ggcagaagaa gaaaaagctg
     4441 tcgacggaca agatatctac acgactttag acagcagact acaaagttat ttagaaacac
     4501 tgatggatca agtaaatgaa gaatatcagc cagaagaatt gacagcagtc ctgatgaaag
     4561 caaaaaccgg agaaatcttg gcaatgggac aacgacctac tttcaatcct gaaacaatgg
     4621 aaggattgac tggaaaagat gctatctggc gtaatttctt ggtacaagat agttatgaac
     4681 caggatcaac catgaaagtt ttcactactg cagctgctat cgaagaagga gaattcaacg
     4741 agaatgaaac cttccaatct ggaaaaatcc aagtagaaga tgctacgatc aatgaccatg
     4801 actttggtga aaaaggtgtg ctgaccatgc gtcaagctct ttcatggtca agtaacgtcg
     4861 ggatggtcat actggaacag cgattaggcg gacgatggta taactattta caaaaactgg
     4921 gatttggaca aagtactcat tctggattag atgatgaagt aaacggtgct ttacctacat
     4981 taaatattgt cgaccgagca atgagtgctt atggacaagc ggtaggtgtg acgaatttcc
     5041 aaatgatgaa agctttcact tctattgcga ataacggtac aatgattcaa cctcgatata
     5101 tcagcaaagt ggtggatccc caaactggag aagagcgaac aactcaaaca gaagttctag
     5161 ggcaaccttt ttcaaaagaa acaacagaaa aagtccgtga atatatgaga gatgttgtcg
     5221 aaagcgaaaa ctacggtagt gcttatggtg tatatagtgt acctggatac aatgtatcgg
     5281 caaaaaccgg aacagcccaa atcgcttctg atacaggggg atatcaaaca ggagatacag
     5341 cctacctgta ttcgattgtg gagatggttc cttctgaaga tccagactat gtcttgtatc
     5401 taacaatgaa acaccctaag acatatgatc gaatggcatt ggctaaaatc gcaaatccat
     5461 tgatgaaacg ggcaatggat tttaaagaaa ctgaagaaga ttcagataca gaaacaaaaa
     5521 cagaaaaagt atccgtagcc gattatcgta atcttgaagc ggacgttgca gcagctgatg
     5581 ctcaaaaaag tggactgcaa cctgtagtga tcggtaatgg taaaaaagta caaaaacaat
     5641 ctactgccaa cggtgatcag ttgatctctg gagaaaaact gatcctatat actggtggtg
     5701 ataagctgat gcctgacgta acaggatggt caaaagcaga tatcatgaag ctggggaaaa
     5761 tcctcggtat tgaagttagt tttgatggag atggttattg tgtcaaacaa gaacttgctc
     5821 catatgaaaa aatcactgaa gacaaactta gttttacttt agaagaataa gaagagaaat
     5881 aggagagaaa agagcatgga atggacacaa gcattgattc ccattgtcag cagttgtgca
     5941 atgacaattg ccgcaatgcc gctatttatt ggttattttc aaatgaaaaa gcaaggtcag
     6001 gcgattcgtg aggagggacc aaagtggcac aatagcaaag ccggaactcc tacaatgggc
     6061 ggcttagtgt ttctgatcgg ctctattttg acaggaattt gggttggagc ttggcaaaaa
     6121 cagctaactc ctactctttt catcttgctt tttgtattag cgttatacgg agtaatcggc
     6181 tttcttgatg attttataaa aatattcaag aaaagaaaca tgggactgaa ctcgaagcag
     6241 aaattgattg gacagattct agggggaatc atcttttatc ttgtttaccg ttctgaaggt
     6301 tatccaggtg tattgaattt cttcggacta gatctacctt taggaatcat ttatggtatt
     6361 ttcgctctct tctggcttgt tggattttca aatgcagtaa atctgacaga tggcatcgat
     6421 ggattagttg ctggcttagg aagtatctct tttgcagctt acggtctaat tgcttggcat
     6481 cagcatcagt atgatgtatt aatcatttgc ttaagtgttt taggaggttt actgggtttc
     6541 ttcgtctaca acagaaaacc tgccaagatt tttatgggag atgtcggttc attagcgttg
     6601 ggcggacttt tagcggcaat ttctataatg ctaaaccaag aatggacatt gcttttgatt
     6661 ggtttgatct atgttatgga aacagcaagt gtgatgcttc aagttacttc ctttaagctt
     6721 acaggaaaac gaatttttaa aatgtctcca attcatcatc actttgaaat gtgcggatgg
     6781 tcggagtgga agattgatac agttttttgg ttgatcagca ttgtgacttc gttgatcaca
     6841 ttatggatcg tttggtagga gatgacggga aatgaaaaaa atatcaacat atgaaaataa
     6901 gaaagtgctt gtcttaggac tcgcaaaaag cggagtaagt gcggccaaat tattacatga
     6961 attgggcgca cttgtcaccg ttaatgatgg aaaacctttt gacgaaaatc cggaagcaca
     7021 agagctgctt tctttaggga taaaagtaat aacaggtagt catccaatcg aattgttgga
     7081 tgaagaattt tcattgatgg tcaaaaatcc agggattccc tacagtcatc ctttagtagc
     7141 aaaagcccaa gaaatgggta ttccggtaat tacggaagtt gagctagctt acgaagtagc
     7201 ggaatgccca attattggga ttacaggaac gaacggaaaa acaacgacaa caacgatgac
     7261 aggactacta ctgaatgcag gagcagatca aggaattgca cgtttagcgg gtaatattgg
     7321 gtatccagca agtggtgtag cgcaagaagc aaaatcagaa gataaaattg tgatggaatt
     7381 gtctagcttc caactcatgg gaatcacaga tttccgccct catatagcgg tgattaccaa
     7441 tatctatgaa gcacatattg attatcatgg tacaagaaaa gaatatgtca aagctaaatg
     7501 gaaccttcaa aaaaacatga cagaaaaaga ttatctgatc cttaactgga atcagtcaga
     7561 actacaagaa ttagcgcaaa gaacaaaagc acgcgtactg cctttctcga caaaagaagt
     7621 gttggaagac ggtgtgtatg ctgacgatta ctcaatatac tataaaaaag aaaaaataat
     7681 ggaaatatct gaacttggcg taccaggtaa gcataatgta gaaaatgcac tagctgctat
     7741 ttctgtagca aaattgtatg gtatatcaaa tgaagctata cgagaaacgt tgcatttttt
     7801 ccatggcgta ccacatcgta cgcaatatgt aggagaaatc caaggcagaa aattttataa
     7861 tgattcaaaa gcaaccaata ttttagcgac taaaatggct ctaagtggat ttgaaacgtc
     7921 taaggtcgtg ttattggctg gcggattaga cagaggaaat acatttgatg aattaattcc
     7981 ttcattaaaa ggaatcaaag caatggtcgt atttggccaa acaaaagaaa agttgatgga
     8041 tgctggaaaa aaagcaggca tcgagacaat agtaacagcc gattctgtag aacaagcagt
     8101 tcctttagca ttagaaaaca gtacagatgg tgatgtagtt ttattatcac cagcgaatgc
     8161 cagctgggat caatacccaa attttgaaac tagaggaaac agattcatgg aagctgtgaa
     8221 ccgattaaaa tagaaaaagt agaagcgagc gataaaaaat gaaaattttg gttacaggcg
     8281 gaggaacagg gggacatatt tatccagctc ttgcctttgt caattatgta aagactcaag
     8341 aaccgaatgc tgaattcatg tatgtgggag caaaacgagg tctagaaaac aaaatcgtcc
     8401 ctgatacagg aatgcctttc cataccttgg agattcaagg atttaaacga aaaatttcca
     8461 tgcataacat caagacggtc cgattgtttc ttaagagtat ccgtcaagca aaaaaaatcc
     8521 tcagtgattt tcaaccagat atcgttatcg gtactggagg atatgtttcc ggagcggtag
     8581 tgtacgctgc agccaaaatg ggtattccaa cagttatcca tgaacaaaac agtgtaccag
     8641 gtgttaccaa taaattttta agccgatatg tggatcggat cgctctttca tttaaagatg
     8701 cggcttcctt ttttcctgaa aacaaagcag ttcttgtagg taatcctcga gcacaagaag
     8761 tagcagatac taaaaaatca gatattttga aaacatttga tttggatcca gaaaagaaaa
     8821 cagtcttgat ttttggcggt agtcaaggag cacttaaaat caatcaagca gtatcagttt
     8881 ttttaagtga atatattcct tcttcttacc aagttttgta tgcttcagga gatagatatt
     8941 atgaagagat cctaaataaa ataaatcctg aaatacaaaa tattagtgtc cagccttata
     9001 tcaaaaatat ggcagaggtc atggcttcca gtgatctgct ggtggggcgt gctggtgcaa
     9061 cttcgatcgc agaattcaca gctctggggt taccggcagt gttggttccc agcccatatg
     9121 ttacgaatga tcatcagact aaaaatgcaa tgagtcttgt tcacgcagga gcagcaaaaa
     9181 tgattgcaga taatgaacta acaggtgaat cactaagtca gacagtcaac gaaatcatgg
     9241 gtgatgaaga attgcaaaag caaatgtgcc gagcttctaa agaacaagga atccctgatg
     9301 cttcaaaacg tctttatgac ttagtaaaac aaataatcaa aaaataaagg cggtggtctt
     9361 agtgagtaag aaaaaagaac caaaaaaatt gtctcatccg tcttctgatg aaaacaattt
     9421 gactccttgg caaaaggcta accgaaaata tctggcagaa caagagatga aaaaccaaga
     9481 gccaaaaaaa gaagacataa cattagatac acccctttca gattctgaag aagaaaaaac
     9541 ggttcaagag gaacagcaag aagaaagcca gtccgagaaa aaaatcgaat tttttgaaga
     9601 gatcaagcaa aagaaaaacg gtggaccata taacggttct tttttgaacc ggctgcccaa
     9661 tttaaaaagt caacggcaca aagtactatt tcgtcggtta gctttgatca tcactgtatt
     9721 gggtataccg ctgatttttt tgatctatta tgtttctcct tatagcaaat tacaagcagt
     9781 tgcagtatca ggcaataaga cagtcaacag ccaagaaatc atctctgata caaaattgtc
     9841 attaggagaa aatgtttggg gacagtattt tcatcgatct acttatatcg atcgccttaa
     9901 aaaagcacag ccaagaatcg aaacagcaaa tatacatttc aaagggatga atgaattcga
     9961 tttggatgta acagaatata aagagattgc tttgatcgca aaaaacaatc aatactaccc
    10021 agtgattgaa aatggaacag tattagatga aaaagtagca aatcctacaa aaaatctccc
    10081 tatcttggaa gagttcaaag actctgcaaa aatcaaagaa ttaacaaagc aatacaatca
    10141 gttatcatca gaattacaaa aagcaatttc tgaaatcaag tacacgccaa gagcaagcaa
    10201 taaaaatctg atccaattga atatgaatga cggcaatcaa gttattgtaa atatcaataa
    10261 tcttgcgaac caaatgaaat attattcgca agtagccaaa gatatggatg aaaaaggtgt
    10321 gatcgacatg gaagttggta tcttctcgca tccttacggt agcactcaag aaacggaaga
    10381 atcgggccaa tcggaagaaa caactgaaag tgaagaaaat gcggatcaaa caaacgaatc
    10441 aagtgaagag gcagaaacgc aaaaagcaca aacacctgga tcgtctagca caaacggatc
    10501 atctgattca aatgattcaa gtgaaacaag tcaaatagaa gataatccaa gtacaactcc
    10561 gtcaagttta aatgaaaatt gataaaacaa ctttaaaaag taagaatgta ctttctaaaa
    10621 accagtaatt tatggtagaa ttggaagcag tgaatatatc tattaataag tatattttaa
    10681 aacggacgct agttgttcgc ttgtatatgg aatagtaagt aggagggaat cccattcatg
    10741 gcaaaaacag gaatgtatgt aggccttgat attggaacga catctgttaa agttgtcgtg
    10801 gctgaatata tcgacagcca aatgaatatt attggagtag gaaacgcaaa atcagaaggg
    10861 attaaccgag gcattatcgt tgatatcgat aaaacggtcc aagcgataca acgagcagta
    10921 cgacaagcag aagaaaaagc aggtatccag atcaaaggcg taagtgtcgg tttgccagca
    10981 aacatgcttg aagtagaaaa ttgccaggga atgattgcag ttaacggaga ttcaaaggaa
    11041 atcaccgatg aagatgtcag aaatgtggct tcagctgccc ttgttcgttc aatacctcct
    11101 gaacgtcaaa tcgtgtcaat attgccacaa gattttactg tcgatgggtt cgagggaatc
    11161 aaagatcctc gtggaatgat cggcgtaaga ttagaaatgt acggtctgtt gtttacagga
    11221 cctaaaacga tcatccataa catacgtaaa tgcgtggaaa atgccggatt aatcgtcaac
    11281 gaaatggtga ttactccttt agcgctgact gaatcaattc tttctgacgg agaaaaagat
    11341 tttggtacga tcgtcattga tatgggtggc ggccaaacaa caacggctgt tatgcatgat
    11401 aagcaattga agtttaccaa tcttgaccaa gaaggtggcg aatttgtcac taaagatatc
    11461 tctattgtat taaatacgtc atttaacaat gcagaagcgt tgaaaataaa ctacggggat
    11521 gcatacccag aacggacatc accagatgaa gaatttccag tagatgtgat tggtcagtca
    11581 gaaccagtga aagtcgatga acgctacttg tcagaaatta tttcagctcg aatggaacag
    11641 attttcaaca aagcaaaaga tgcattggac caaatcgaag cattagagtt gccaggtggc
    11701 gtcgtattga caggcggagc tgctagtctt cctggtgttg tggacttggc acaagaaatc
    11761 ttcggcgtaa atgtaaaatt gtatgttcca aatcacatgg ggctgagaaa cccggtattt
    11821 acaaatgtaa taagtatcgt ggattattca gcaaacttga gtgaagtgta tcaattggca
    11881 aaaattgctg ttacgggtga aacctcagca gctcgtcaaa tggtagttga acaagaaaca
    11941 acaaacacat atgagagcta tgaagcacct gaagaaacaa tctacgatga gccggaacca
    12001 aaagagtccg gagaaaatgt aaaaaataaa atcaagggtt tctttacaaa tatttttgat
    12061 taattcatcc tgggaggaat aagatatgga attctcaatt gataataata tcaatgacgg
    12121 cgcagtaatc aaagtcatcg gagtcggtgg tggcggtgga aatgctgtaa accgaatgat
    12181 tgaagaaaac gttaaaggtg ttgaattcat tacagccaac acagacgtgc aagcattaaa
    12241 aaattcaaaa gctgaaacag ttatccaatt aggccccaaa tatactcgtg gtttaggtgc
    12301 tggttctcag ccagaagttg gacaaaaagc ggcagaagaa agtgaacaat ccttacgcga
    12361 agctttagac ggtgcagata tgattttcat cactgcagga atgggtggag gaaccggtac
    12421 aggtgctgca ccaatcgttg caggtatcgc gaaagaattg ggcgcattga ctgttggtgt
    12481 cgtgacacgt ccattcactt ttgaaggacc gaaacgtggc cgttttgctg cagaaggtat
    12541 cgctcgtttg aaagaaaatg tggatacatt attaattatc tcaaataacc gtttattaga
    12601 agttgtagat aaaaagacac cgatgcttga agctttccgt gaagcagata atgttttacg
    12661 acaaggtgta caaggtatct ctgatttgat cacagcgcca ggttacgtta accttgactt
    12721 tgctgacgtg aaaacagtga tggaaaacca aggtacagca ttgatgggga tcggtgtggc
    12781 tagtggagaa gatcgcgtag tagaagcaac gaaaaaagca atctcctctc cattgcttga
    12841 aacatctatt gatggagctg aacaagtact tcttaacatc acaggcggtt tggatatgac
    12901 attgttcgaa gcacaagatg cttcagatat cgtagcaaat gcagcaactg gcgatgtaaa
    12961 tatcattcta ggtacatcta tcaatgaaga aatgggcgat gaaatccgtg tgacggtcat
    13021 cgcaacaggt atcgatgaat caaaaaagga acgcaagtct agccgaccag ctagacaagc
    13081 acaaatgcaa tcacctgctc aaaagactgt attagatatg gatcaagcta aaccaacttc
    13141 ttcagaagaa gaaaacagtt ttggcgattg ggatatcaga cgtgaacaaa atgttcgtcc
    13201 tagagttgat gattccaatt ttgacaatat cgaaaaaaaa gaatttgata cattcaaccg
    13261 cgaagaaaca aaatctcatg gcgatgatga attaaatacg ccaccgtttt tccgtcgtaa
    13321 aaaataaagg agaggaagag cacatgattg ctgacaactt gcagaaaatc aagcaagaaa
    13381 ttcaggattc gtgtgctctt gttcatcgtg atccgaaaga agttacatta gtagctgtaa
    13441 caaaatctgt tgaatccgct caagctgaag aattggttag agctggcgtt atgaattgtg
    13501 cagaaaaccg agtagataaa ttattagaaa agaaacaaga tttatttgat tttcctgaaa
    13561 taaagtggca tttaattggt aatttacagc gcagaaaggt aaaattgatt gtaaatgaaa
    13621 ttgattactt tcatgcgttg gacagtttaa gattagcaga agaaatccag aagcggttag
    13681 agaaagaatt atcctgtttt attgaagtaa atgtttctgg tgaggaatca aaacatggaa
    13741 tttcaccaga tgagctttta ccgtttgtgg aatctttagc tgcctgcaca aaaatcaagg
    13801 ttgttgggtt gatgactatg gcgcctaaag aagcttctga tgagcaaatc cataaagtgt
    13861 ttggtacgct gaaagaattg cgtgatcttg ttcaagcaaa aggttatgcc catgcaccat
    13921 gtagtgaatt aagtatgggg atgagtcaag actttcaaat tgcgattgaa gaaggtgcaa
    13981 catttatccg tgtaggaaca gcgctattca aagacgaata aaggaggaac aaaaatgccg
    14041 cttttaaaca gaggagcaat tgctaatttt ttcggattag ctgatgagga agagtacgaa
    14101 taccaagatt atcctgaaac aacaaaaaag gctgtacagc caactaaaaa aaatacaaca
    14161 cagaatcaat caactcattc tgtatctgct gcgaatactc atgaaaaaca aaaaacggcg
    14221 acttcacgtc ctgtaacgca tgaaagtatt cagccggctg aaaagaaaaa agtaattgaa
    14281 ctacatcaat cacctacaaa aactgtagcg aaagaaagaa cagcttcaag aacctctaca
    14341 caacctaaag caaatcttgc tggaaaaatc actgtaatgg aaccaagagc ttattctgaa
    14401 gctatggcga ttgctaaacg aatcattgct ggagaagcaa ccttagtgaa ttttcattta
    14461 gtagaagaaa aacaagcgag aagaatcgtt gattttctaa caggaacagt ttatgcacta
    14521 gatggagata tcaaacgtgt tggagatgag atttttcttt gtacaccgac tgggatggag
    14581 attgacagtt caaccgctca atcttttgca gatgcgaatt tgtttgatct gtaagaggag
    14641 gaactacgat ttatactatt gcactattac ttcatttact tcaacgggca gcctatttct
    14701 atagcattat cttgatggta tatgcattgc tctcttggtt tccaggcggg tatcaatcag
    14761 ggctaggacg attattagct aagatctgcg aaccgtatat cagtttgttc gatcgtctgc
    14821 ctttgaggat tggacccttg gatttcacaa ttttaggggc aatcctgatc ttgaacttag
    14881 ccgtacaagg tttagcacag atcgttatat ggataactgt ccatttagtt tattgattga
    14941 agcaacaaaa tctttattct cagaatagat aggaggggaa aattttggat gcaaatgtat
    15001 accagcactt tcgggcagat gaacgtacat ttatcgattc ggtaggcgat tggattgaac
    15061 aggttcaagg acaatatgca ccctatctga ccgaatttct tgacccaaga caatcctata
    15121 ttttagaaac actgattcga caaagcagtg atttgcgttt catgttttat ggcggatatg
    15181 aacaggcaga aagaaaaaga tgtttgattt tccccgatta ttacgaacct gtagaggaag
    15241 attttgaaac agcattgtat gaaatccatt atcctagcaa atttgccagc ctaagtcatg
    15301 ggaaaatcct tggaacttta gtgggaacgg ggatcaaacg ctcttacttt ggcgatatca
    15361 tctcggacgg tgatcgctgg caagtattta ttgcaaatga ggtggatcat tttgttgctg
    15421 cacaagtaac aaagattgga aaggttgctg tacgcttgga accaatcaaa tacacagaaa
    15481 tgattatgcc gaaagatagc tggacacaag aaagaggaac agttagttcc atgcgactag
    15541 acagtgtgat ctctgagatt tataatattt ccagacagcg gtccaagcag ctgatcgaag
    15601 ctggtaaagt aaaagtgaac tggacagaaa atacaagacc tgattttgta cttgaactat
    15661 tagatattat ttcagtcaga ggttatggca gagtccagat ccaagaactt gaggggaaga
    15721 cgaaaaaaga aaagtacagg gtactgttcg gtgtattacg taaataaaat aaaaaggtgg
    15781 tttactcatg gctttaactc cattagatat ccaaaataag acattcccga caaaaatgcg
    15841 gggatataat caagacgaag tagatgattt cttagattta gttgttcgtg actatgagga
    15901 attgactcaa agaaatcgag aattagaaaa agcagtcaaa cattctgaag aaaaacttga
    15961 gtacttcaat gaattaaaag atgctttgaa ccaatcaatc atcgtagctc aagatacggc
    16021 tgataaagta aaaacaagtg caagcaagga atccgaagtg atcgttactt ctgcacaaaa
    16081 caaagcagat gagttagttg cgaacgctga aaaacgtgca catcaattaa caactgatgc
    16141 agaagaaaaa gcaagaaaaa tcttgacaga tgcaacagaa aaagcaagac agcttgcgac
    16201 agaaactgaa gatcttaaga aaaaaacacg agtattccat caacgtatca gcttgatgct
    16261 tgagtctcaa ttagaacaag tgaaaagtcc ggaatgggat gaaattttac aaccattctc
    16321 cagctacgtg actgacagcc atgaagtgat caaagaagtt ttagcaaaac agcttgacaa
    16381 tgaaaatgat actgatgtaa actcagacac aggagtcata gaagcaccta tgacggcatt
    16441 tgatacacag gctattgata tctcgatcgt gcctggtgaa aatgaaaacg agtagaacag
    16501 aaaagcactt tgttattctt aaagcgagcc gatgagagtg gaagttcggt aagacactgc
    16561 atggtgaaag atcctctact tgagacctgc ttttccgaaa ttagagtaag aagcagcggc
    16621 tgacctcgtt attggtcaca gagagtttgc actagataga tgcaactaaa tttgggtggt
    16681 accacggcat gttcgtccct tgcggctgaa catgcttttt tgtgtccgga aaacaaataa
    16741 aggagtgtat ggttgaatga aaatgaaaga aaccttgcaa ttaggaaaaa caaaattccc
    16801 tatgcgtggt aatttgccaa accgagaagg cgagtggcaa aaagaatggg aagaaaatcg
    16861 aatctaccaa aaaagacaag agttgaacga aggaaaacct agctttgttc ttcatgatgg
    16921 acctccatat gccaatggta atatccattt aggacattca ttgaataaaa tcagtaaaga
    16981 cattatcatt cgttcaaaat caatgtctgg ctatcgtgca ccatatgttc caggatggga
    17041 tacacatgga ttgccgattg aacaagtatt ggctaataaa ggcgtgaaac gtaaagaaat
    17101 gtccatggca gaatacttgg aaaaatgtcg tgaatatgca ctttcccaag tagataagca
    17161 acgagcagat ttcaaacgcc taggagttgc aggagattgg gaacatcctt atgttacatt
    17221 agatccttct tatgaagctg cacaagtacg cgtatttggt aaaatggctg aaaaaagcta
    17281 tatttacaaa ggattgaaac caatttactg gtctccgtca agtgagtctt ctttagcgga
    17341 agctgaaatt gaatataaag atgtaaaatc tccatctatt tttgtagctt tcaatgtcaa
    17401 agacggcaaa gatattcttg atgaagatac agcttttgtc atttggacga caacaccatg
    17461 gacattgcca gcaaaccaag gtattgctgt aaatccaaaa tttacgtatg tattggtgga
    17521 agccgatggc cgtaagtttg tcgtagcgaa agatttgcta gaaacagtcc aatcagaaat
    17581 cggttgggaa aatgtaacag ttctaaaaga atttgctgga caagaaatgg aatatatgac
    17641 tgcaagtcat ccattctatg aacgtgaatc acttgtgatt ttaggcgatc atgttacttt
    17701 agacgctggt actggattag tccatactgc tccaggacat ggggaagatg actatatcgc
    17761 tggtagcaaa tataaactat ctgtagtgtc acctgtagac tcaaaaggat tgtttacaga
    17821 agaagcacct ggatttgaag gtatctttta tgacaaagca aatcctatga tcactgatct
    17881 attaaaagaa aaaggagctt tgctgaagct agatttcttt actcatagtt atcctcacga
    17941 ttggcggacg aaaaagcctg tgatctatcg ggcaactcca caatggtttg catctatcga
    18001 taaattccgt cagaatattt tggatgaagt agaaaaagta gagtgggtta tcccatgggg
    18061 taaaacacgt ttgtataata tgatccgtga ccgcggcgat tgggtaattt cccgtcagcg
    18121 tgcatgggga gtaccacttc cgattttcta tgctgaaaat ggagaagcaa tcatcacacc
    18181 agaaacaatc gaacatgtgg caaaattatt tgctgaacat ggatcaatta tctggtttga
    18241 aaaagaagcg aaagaacttc ttcctgaagg atttacccac ccaggttctc ctaatggcga
    18301 atttacaaaa gaaaaagata tcatggatgt ctggtttgat tctggttctt ctcatgaagc
    18361 tgttttacgt cagcgaccag aattatcatt cccagcagat atgtatttag aaggatcaga
    18421 ccaatatcgt ggctggttca actcaagtat cacgactagt gtggctatca atggtgtagc
    18481 accatacaaa tcagttattt ctcaaggatt tgctttagat ggtgaaggcc gtaagatgag
    18541 taaatcttta ggaaacatca ttgcaccaga aaaagtgatc aaacaatttg gtgcagatat
    18601 ccttcgctta tgggtatcta gtgtagatta tgaagcagat gttcgtgttt ctatggatat
    18661 cttaagtcaa gtggcagaag tatatcgtaa aatcagaaat acgatgcgtt tcttattagc
    18721 gaatacagaa gatttcgatc ctaaaaaaga tactgtttcg tacaatgatt tacgttctgt
    18781 agacaaatat atgaccgttc gattgaacca agtaatcaaa gaaatccgag aagaagggta
    18841 cgacaaatat aacttcatgc atatttaccg tacagttatg aacttcttga cggttgatct
    18901 atcgtcattc tacctggatt ttgctaaaga tgtagtttat attgaagcag aagatgatta
    18961 tcaacgtcgt tgcatgcaaa ctgttttcta tcaaacagct gtagctttga caaaattatt
    19021 gactcctatc attccgcata cagcagaaga aatctggtca ttcctgaaag aagaagagga
    19081 gtacgttcag ttaagcgagt ttcctggtta tgaagagttt gcaaaccaag aagaattgat
    19141 ggatacctgg actgctttca tggacttccg tgataatgtc ttaaaagcat tggaagaagc
    19201 aagaaacagc aaattgattg gtaaatcttt ggaagcaaaa ctaactgttt atccaaaaca
    19261 acaagttcgt gaaatgttaa aagctttgga tgcagatatt gcacaattat tgatcgtttc
    19321 accagactac tttgaagtta tggcagcaga tgaacaagtg ccagataacg ctatggtatt
    19381 tgatgatgtt gctattacag tggaaaaagc agacggggaa acttgcgatc gctgtcgcca
    19441 agttcgtaaa gatgtaggag tagatgaaaa acttcctcat ctatgcggtc gttgtgcaaa
    19501 aatcgttgaa gacttctatc ctgaagctgt agctgaagga ttcgaagaaa agtaaaaggg
    19561 aaaagggggt gtgacatgtt ctttgtcaca cccccttttg ttatcaatcg tttaattttc
    19621 cacgttcacg ataccagtta tctggttgcc agatccattc gaatccgtct ttttcaagta
    19681 gttcgaaagc tgctttaggt cccattgatc cagctttgta gttgggaaaa tccggttgtg
    19741 tttggtccca agcttttcga atgacatcca cgatatgcca agattgagcg acttcttccc
    19801 aatgagagaa gttcgttcca tcaccattca acgcatctaa tagtaatttt tcgtaagctt
    19861 ctgggctatt ttcaaccatt tctgcactat ttctaaattc caatttgatt ggttccgttt
    19921 caaatccttg ccctacttct ttcccattca aggataaaga aaatccttca gttggctgaa
    19981 tatagatcgt tagaacatta ggtggaagtg tcgtatcgtc acatggttca tcgacagatg
    20041 ttttgaatac attaacagga acttgtttga atacgatgtt gatccgagtc cctttttcag
    20101 tcaaacgttt gcctgtacgt acatagaaag gaacacctga ccaacggaag ttatcgatag
    20161 tgaatttgcc tgcgacgaat gtttcagtct ctgattgagc atccactttg tcttcttcgc
    20221 gatagccctt gaattgtaca ccatccaatt caccttgagc atattgcccg cgaacgaagt
    20281 tttctaacac ttcttcttcg ttataaatgc ggatagcttt caatgctttg atcttttctg
    20341 tacggatttc tttttcggaa aatgctactg gcggttccat tgcaagtaat gctacaacct
    20401 gtaaaatatg attttgcacc atgtctttaa gtgcgccact atgatcgtag tagcccccgc
    20461 gatcttctac accgaggttt tcgccaaaag taatttggat attgtcgata tagcgattgt
    20521 tccattgagc ctcaaaaata ttattggcaa aacggatagc tgagatgttt tggatcattt
    20581 cttttcctaa ataatgatca atcctgaaaa tatcttgttc tgggaatact tctctgattt
    20641 gctggttcaa ttcaaaagca gactggtaat cagaaccgaa cggtttttct atgatcaaac
    20701 gattgaagcc attttttgtc ataatatttt gtgatttcaa atgagaaacg atcgttccaa
    20761 aaaattgagg tgccatagcc aaataataga cacggttacc gtttaattga tagtgtccat
    20821 ctaatcggtc agacaattct tttaatgtct gataatgcgt tgaatcattt acatcatggg
    20881 attgatagta aaaatggctt gcaaaggtag ttgcttcttc atctgaagga ttcaatgcac
    20941 ggattgtttc tttgacaact tcacggtagt gctcatcgct ccagggacgg cgagcggttc
    21001 cgattacagc aaaatgctcg cctaaatttc cttttctgta aaggcggaac aaagacgggt
    21061 acaatttacg ctgggctagg tcacctgtac cgccgaatat cgtaaacaat acattttttt
    21121 cattagacat gtggatacac tcctttatat tttatcgaca aaaatcgtgc tggccgcctt
    21181 aaagctgacg gggattttct ttctatcatt ttggatagtg atcggtcctt cataagctgc
    21241 gatgtcaacg atctcatatt cttcgttgat attcaggtca atagtgacta agtaatccaa
    21301 caattctttt tcatcaagca ctcgtgcgat acgcactttt gtaccgacag gataggactc
    21361 caatgtttgt cggcgttctt catggacaac ttcctctttt ttaggaatcg atcctccatg
    21421 aggacaatgt tcaggatgat tcaaatagtt ttctaaatga tctgcaagat gttccgaagt
    21481 cacatgttcc aatacttcag catcatcatg gacttcattc cagctatagt ctaaatgttc
    21541 aactaaaaaa acttcccata agcgatgttt gcgaatcaga ctgctagctt tttgcagtcc
    21601 gcttgcagtc aattgtacac cttgataagg ggaatgttct acaagctctt ctttcacaag
    21661 tttagaaatc atttcactga cagatgcagc tgagacatct agactagata cgatttgttt
    21721 attgttgact ttcgttgtat ctccacctag ttctaaaatg attttcaaat aatcttctcg
    21781 atttggtgtc atattcgatc atcctttcat ggtaaaaaac catcattagt aagtgtaaca
    21841 aaaaaaacgt taattgacta tttttctaaa taaaaaacaa aggattttta gacgttttta
    21901 caacaaaaaa cgaaagatga tagagaagac tcattctttc gtttataaag gatatatata
    21961 tacattggga gggatctatt tttcagataa caacttatat gaagtgtctg cagattcgtc
    22021 ataaagagtt tgttcgggat aagaaaagat aagataaaaa ccatactgat cacgtacgac
    22081 taaacgatat tcatctattt ctaccacaga tgtgccaaga gactgaccgt tgatcaaaaa
    22141 cgtgtaatca gatgtaatct gtaattgttg tttttgctgg ctatcactaa agaaccatgt
    22201 accttgatac tttgagagtc cttctgactt ttccgcttgt tttttctttt tcaagtaaat
    22261 aaaacttgag agaacggtaa tgagtgaacc aagaaaatag atcatttttt ttatcaccaa
    22321 atcactcctt tatgagaaaa taatcgcata gacatattct ttcttcttta tttcattgta
    22381 ccgaataaaa gctaaaattt ctctaagact ttcgactggt ttttttactg tttttctaca
    22441 aattatgata ggatacatag taggaagaaa ggtgacataa tttgaagtat cagcaagtgg
    22501 aaatagcttt ttttattgac cgcccgaatc ggtttatagc acattgtatg aaaaaagacg
    22561 gagaaataat tattgcgcat gtcaaaaata caggtagagg aaaagaggtc ctgataccag
    22621 gcgctgaagt ggctattgta tttgctcctg gacctaaacg gaaaaccgcc tatgatctga
    22681 ttgctgtaaa aaagaagggt gactggttta atatcgatag tcaattgcct aatcggctgg
    22741 caattgatgg tattttagac ggcacgatcc ttttaccagg attaactggt ccatttacgg
    22801 tatacaagcg tgaagtaact tatcttcact ccaaatttga tatttattta gagacggtgg
    22861 tcggacaaaa agcatttgtt gaagtcaaag gtatgacact tgaaaataaa gcgattggtg
    22921 cttttcctga tgcgcccaca ctcagaggat tgaaacatat aggagaatta acgtatgccg
    22981 cacaagatgg ttatgccgct tatgtcttgt ttattgctca gttcgaacat cttcatctgg
    23041 caacgatcca tgaagaaatg caaccagcac tagctgatat ggttcgacat gcgcagcaaa
    23101 gcggagttca aatcctcgcc tataattgtc aagtatcggc agatgaggta actgtcaagc
    23161 aggccattcc atttgatgta gatatccctt ttgaagatcc tatacaatag aaagaaggta
    23221 aaataatgat caacttaggt attatcggaa caaattggat tactcatcaa tttgtccaag
    23281 cagctttaag cacaaaaaaa tatgaattga cagcggtata ttctagacat ttggaaaaag
    23341 cacaggaatt tggttctcat tatgaagggg atatcgaatt cgcaacagat ttgaagactt
    23401 ttttcaatat tactcatatg gacaccattt atattgcttc tccgaatagt cttcacttta
    23461 gtcaagctaa gcaagcaatt ttggcaggaa aaaatgtgat agttgaaaag ccagcttttt
    23521 cgacgccaaa agaaatggat gaaatcatcc atttggcaaa tgaacacaat gtgtattttt
    23581 ttgaagcagc aagaaatatc catgaatcag gttttaaaaa gattgccgat tacttaccat
    23641 taaaagacga gataatcggt gcaaatttca gctatatgaa atattcttcg cgctatgacc
    23701 aagtattaga tggagaagaa ccgaatatct tctcgactca tttctcaggt ggtgcattga
    23761 tggatttagg tgtttacctt gtatatgcag ctgttgcttg gtttggaatg ccaaaagaag
    23821 tccattattt cccaagaaag atttctactg gtgtagatgg tcttggatgg gggatcttac
    23881 gttatgagaa ttttgatgta tcgatccagc caggtaaaat cggtgattct tatttaccgt
    23941 cagagattta ttttgactca ggaacgctag tgatgaatgg agtcaatgca attgaacaag
    24001 cacaatttca tgatcgcgcg cataaagaaa tcattgattt ggcggtaaca gctgcagaaa
    24061 atccaatggc agatgaagca gaggattttg ccaatgtcat ggctcatccg aaagatccag
    24121 cttggggatt gttgtatgaa gagtggatcg agctagctag aaatgtgaac caagtgattt
    24181 atgatttaag aaaaaatggc ggcatcaaat tcgatgcaga taatgaggaa gatttttaat
    24241 gaacgaattt gtacaagtat ttcccgaaaa ttggcagaaa aaatatgagg ataaagggtt
    24301 tatctcacct tctcttattc aacgagcagt ttttcagcca ctaagtaata aacaaagtat
    24361 agtagcggtt tctcctacag gttcaggtaa aacactggct tatctttggc ctctactact
    24421 aaacgtggaa ccaggtgaag caagtgcgtt ggtcattttt gcttcttctc aagaactagc
    24481 tattcaagta gcagatgttg cacgtgaatg gggaaaagac aaagagttga aagtccaatc
    24541 tttggtgggc ggagccaacg tcaaacgtca gattgagggt ttgaaggaaa aaccagaaat
    24601 cttgattggt acaccaggaa gaatattgga attgatgaaa gcaaaaaaaa taaaagcaca
    24661 tcaagtgaaa acaatggtat ttgatgaagc agaccagcta tttgacgctg ggaacagcca
    24721 aatcattgat caaattcttc atcaagctcc aacagagtat cagctagctt ttttttcagc
    24781 gacagcagat cgttcccttg aaagcattga aaaaatcact gggaaaacgt ttgagacaat
    24841 tgacgtgaca gcagaggacg attctcgaaa aggactgaga cattactttt tacgtgtacc
    24901 gatacgaaag aaagatgact acttgagacg tctcacgcat atagaagatt ttcatggtct
    24961 gattttcttt aatcaactga ctgaattagg cgtaatggaa gaaaaattgc tgtatagagg
    25021 tgtaccggta ggaagtctgg cctctgatca gaacaagcta ctccgaaaag cagcgctaga
    25081 acaattcaaa aagaaaatgg tcagagcact tttgaccaca gatgtggcgg ctagaggttt
    25141 agatattaca ggtcttcctt atgtagtgaa tgcagaagtt ccgttaagtg aagaagctta
    25201 tttgcatcgt tcgggaagaa ctggtcgaat gggtaatgaa ggaatagtaa ttacactcgt
    25261 acaagataat aatctaagag atttaaaacg gcttttacgt ccatcaaata taacacttga
    25321 agagattttt ttatacggag gtaagctgca aactgagcag ccaaccaaag aagatgcagc
    25381 tcctgcagta aataaaaagt atgcgaaaac tttttctgga aaggagcaga acccagaata
    25441 taacaaagaa aaaataagaa aaaaagttaa aaataaatca aaaaaagaga gaaataaagg
    25501 agcaaggcgc aaataagcgc ctttttatgc tatgattatg aaaacgggaa caaaattggt
    25561 tgccagagga ggggttatgt gaaagaacgt caagaagaga tcttgcagct attgacagaa
    25621 aaccaacaag gattgacagc aagtgatgta gctgagcgct taactatcga tcgaagcaat
    25681 gcaagccgat atttaagtga actatacaag gcccatcata ttgtaaaaac cgctggccga
    25741 ccagtcgttt actctttgcc aacggaaaag tcaaaatctg atgaagtgca tgtcgactct
    25801 tctacgcaag tgacttttga aacactcgtt ggagaaaatg attctttaaa agtcagcata
    25861 cagcaggcaa aagctgcgat tctttatcca ccgcgggggt tgcatacgat tatttttgga
    25921 gaaactggta cagggaagtc gatgtttgct gaatgtatgt atcattttgc aatcgattca
    25981 gagatgcttt ctgcagatgc gccatttgtt tctttcaatt gtgcggatta tgctcaaaat
    26041 ccgcaactgc tctttggaca catctttggg atcaaaaaag gggcttacac aggagcagct
    26101 caagatagtc ccggtctaat agccaaagca gacggcggta tattgttttt agatgagatc
    26161 caccgtttac cgccggaagg gcaggaaatg ctgtttactt tcattgataa aggtatttac
    26221 cgtccgcttg gagaaagtgc acaagtacat gaagcatctg ttcagatcat tggggcgacg
    26281 actgaatctt cagaaagttt cttatctacg ttcaatcgac ggattcctat ggcaatcacc
    26341 ttgccgaatc ttgcttcacg ttcactggat gagcgttatg aaatcatctc tctttttatc
    26401 aaacaagaag cgaatcgttt gaatcaacgt atcgatatcg aaaaagaagc gattcttgcc
    26461 ttcatgcttt atgatgcgga aggaaatatc ggtcaagtga aacgagactt gaaactagtc
    26521 tgtgcaaaat cttttttaca ttaccgtact catcatgaga aaaagctaat cattcgaaaa
    26581 gaagaacttt cccttcaagt acaaaaagga ttactgaaaa tcaaggaaat accggaacgt
    26641 ctcgaccgat tcatggacag caaaagtcag tatttgacat ttgaaccagg atttgctgat
    26701 gttgtctggt cacaagatcc agaacgaaac atgcaggtct ataacgatat tgaggaaaaa
    26761 gtcacttctc tttccgaaac cggtgtggag aacattgatc tagagaccct catttcaaaa
    26821 gatgtggatg cttatttcca gacatatgtc aaagaattga ctaaaagttc gattcccaaa
    26881 gatcttttgc cagatgaaat ctggcggtta accaatcaat tgtatgatgt ggctgaaaaa
    26941 cggttagacc gtatttataa tgaaaaagct cgttttgctt ttgctttgca tctgcaaagt
    27001 acattggatc gtgtgagaga aggtcatatg atcgtccacc cagatttgaa taacgtacgg
    27061 aaaaatttta agagggaatt ccaggtagca atcgatcttt caacgatcat tgaagaagaa
    27121 gaacaagttg agattccttt tgatgaaatc ggctttatta gtatgtttct ttctatcaat
    27181 ctaggagaaa gtgagcctgt taaagaaaac aaagtagatg ttctcatatt gatgcacggc
    27241 agacagactg cttcaagcat gttggagatg gcacaagaac tattaggaac aaaagtaggg
    27301 aaagctttta atatgccact ggttatggaa gttcaaacaa tgtatgaaga agtgttacaa
    27361 tatgtcaaaa actatcaaga gcatttgacg aatggcctac tcttgttaac agatatggga
    27421 tcattaaaca ccttcagtga tttgatttat gaagagactg gcattcggac gaaagctatc
    27481 acgatgacaa gtaccatgat tgtgatagaa gcgatacgga tggcaagtgt tggaagaagc
    27541 ttagaagata tttatcaaaa tatccagctt tcctttgaat cgatcgtacg tgatcagttc
    27601 aaagcggaaa agtctgaaac tttacagcgt aaaaaagccg taatcgtgac atgctttact
    27661 ggtgaaggag tagctgccaa attatatcag cgtattatgc cagtgattaa tcaaaataag
    27721 gtagaactga tccagatgca gtttttagaa cgtgaatcat tcaaaaaaca catcgatgcc
    27781 ttattggaag aatatgagat caaagcaatt gcgggaacag ttgatgttga ttatcaaaat
    27841 atcccatttt tttcagccta tgacgttttt gatgatgaaa aactaaatat tttaaagcgt
    27901 atagctgatg atgagatccc gacagctaaa attgtcgatt cacttgctgg atcattaagc
    27961 gatgtctttt ctattgatga actgatccgt tcattgcaaa agacagttca gcagatccag
    28021 accgatttgt cgattatcgt ggaacctgga gtagatactg gaatcgttat ccatttagcc
    28081 ttcatgttag acggattgat caaacaagaa agccatcggc aatttgagaa actgtctatt
    28141 ttctcaaaaa tttatcgttt ggaaatggat atcgttcggg caaacttgat ggcactagaa
    28201 cgaaaatatc aggtaaaaat tccagaagat gatatcgcat ttcttacaca aatgtttctt
    28261 gaaaataaaa taaaaaaatg aacacactaa tcatactgtt tacacactaa acatctgtgt
    28321 gcgcactata aaaaagagct aaaaagcatg aaaacgctat ttcagctctt ttttttattg
    28381 gcatgcttct tgcgttatat aaaagtgtaa aaaaataaaa ggagtgttaa aaatggcaaa
    28441 aaaaacaatc atgttagttt gttcagcagg gatgagtacg agtttattgg tcacaaaaat
    28501 gcaaaaagca gcagaagaaa aagggatgga agccgatatt tttgcggtct ctgcctcaga
    28561 tgcagataat aatttagaat ctaagaatgt cgatgtatta ttattaggtc ctcaagtacg
    28621 tttcatgaaa gctcaatttg aacaaaaact tgcgcctaaa ggtattccat tagatgtcat
    28681 caatatgcaa gactatggca tgatgaacgg agaaaaagtt cttgcacaag cagaaaatct
    28741 aatgaaataa atcaagtatg cagttggggg tataacaacg tggaagatca acaaaatcta
    28801 gaagccatca tggggttaat catgtttggc ggtaatgcaa agagcgatgc aatggaagcg
    28861 attgcggctg ctaaaatcgg tgattttgag ttagcggata ggaaaatcgc tgatgcagaa
    28921 gaatcactta tacaagcgca tcatgcacaa acagacatgt tgacacaaga agcacaagga
    28981 aatcatatgc aagtgacatt attgactgtt cacagtcaag atcacttaat gacatctatt
    29041 gcgtttactg atttagcaaa agaaatcatc gaactttatc gtcgcgtata cagcgaataa
    29101 atacaacttc ttttttgaac ggaagaagaa aaatttttga acggattttt tattttgtta
    29161 taaggagaac tctctttata taaaaaactt ataggaggaa gtaaaaaatg aacggactat
    29221 caagttggat ggagaaatac atcctgccgg ttgccgcaaa aatcggagcg caaaaacatt
    29281 tagttgcttt gcgtgatgct tttatcggca cactgcccgc aacaatggcg ggatcagtcg
    29341 ctgtaatgat caatgcaatt attcgtgatt taccgcaaca gtttaacagt acctatgctg
    29401 acagtttagc agcagacaaa ggaatctttg ccgtattgaa tgtcatcatc ggaatcaatg
    29461 gttttgtctg gaacggtaca ctagcaatcg ccggattgat ctttgccttt tcttgggggt
    29521 ataatcttgc ccgagcttat ggagtaaatg atctagctgg ggggatcgtt ggtttagcta
    29581 ccttgattca aggtatttcc tttggtccag cattatcagc agcattagat gtgaatgttc
    29641 cttcaaatgt cgcagatgca atcaatagtt ctgagattgg tgcaacgatt gcagatggca
    29701 cactgtcagt tggattatgg ggttggctaa aactagatca tttgaatgga aacgcttatt
    29761 ttacagttat gatcatggga gctatttcag tcattatttt ttgtaaattg atgcttgcca
    29821 acattacgat caaaatgcct gattcagtac caccagcagt atctaaagca tttgcagcca
    29881 ttttaccagc gacgatcgct ttatacgtca ttgctattat caattatatc gtaggtcgtg
    29941 tagctgatgg gcaactgatc attgatttgg tgcaaaaata tattgcagaa ccattcctag
    30001 gattatctca agggttggga gcagtattga tcgtcacagt atttgttcaa gtattctggt
    30061 tctttggtat tcatggacca aatgtattgg caccagtgct agagggaatc tggggacaag
    30121 cacaactaat caatattgat attttccaaa aaggttataa cggaaaaact ggtacaccag
    30181 ccgtgttaga tgcaatcgaa gatggaaaag cttatatgtg ggtccgcgga tcgttcgatg
    30241 cttttgcatg gtttggcgga tcaggcggaa cgatcgtctt actgatagct atcttgattt
    30301 tctctaaacg tgcagattat ctaacagtag ctaaattatc cattgggcct ggtatcttca
    30361 atatcaacga accagtgatg tttggtctgc caatcgtatt gaatgcaatc atgtttatcc
    30421 cattcttgat tgctccagta gtagcaacag caattggatg gacagctact tatcttggcc
    30481 tagtcgctcc ggtatcgcag caagtcacat gggtagtacc gccgttctta ttgtcattct
    30541 tagcaacagg agcggattgg cgggcaccga tcgtaacatt agtatgtatg gtcgtgactt
    30601 tcttgatttg ggcaccattt gtcatctctg caaacaaaat ggaccctgcc gcaggcgaac
    30661 aacaataaga tgaacgtgag gagcgggacg ctttaagttt cgttcctcat aatgaatttt
    30721 cgaggaggaa ctgaaatgat tacaattgcc agtgcaatgc aacaagatga aatcaaagaa
    30781 ttgttagaag gatacaatga agaaggaatg acttttacat ttaaagaaaa acaaggaatc
    30841 aagctgttct ttgaaacaag tgcagaagat ccggaagttg cggctaaaaa agcaaaggaa
    30901 ctaatcaaag cacagccttg gggaacagtc ctttattttc aatcaacagc tgtttagaaa
    30961 atggtttaaa aagataggat ggttgagatg ataaaaaacg gtttattttt atgtagtatt
    31021 ggttctttga tcgtgttgta tagtttgaat ccacattcgc aaaggtatga tttgtatagt
    31081 atggtcacag gtctttttct aacaggatta ggaatctatt tcttcatgaa ggggaaaaaa
    31141 agagaagaag caaaggagaa aaataactaa tggaaatcac gaaaaaatta aatattccag
    31201 catcgttttt ttacgataaa gttatggact ctgtcctttt cgatgtacgt aaagcgaccg
    31261 gcaaatcagt aactagaaaa cagctgaaaa atttggagta cgtcaaacaa ttctcgcaaa
    31321 ataaccgggc tcgcataaaa atcgaagaag tcattgaaaa ccagtcttat aagtttcgta
    31381 catcgacaac gaagaatgaa ttcgtcgttc attatcaaat caaaccattg gacgattcga
    31441 cctgtgaggt tcattacaca gaaaaaatgg agtcttatgg catgcttcaa aagttgaatg
    31501 atatgctttt aggaacaatc ttgatgtatt ttaaacggag acgtttcaaa aaaatgctag
    31561 atatgatcga agcaacgtat taaatcaatg aaacatggta ctatttagtt attgaaaaat
    31621 gaagtaagct agaaggaatt tttcatagga agatagatct ttcctgcgaa tcctcactag
    31681 cttttttgta ggaaggggca gcaaaatgac aaacaaagta agagagctag gtgtatcttc
    31741 gattgaggaa atgtttgatt tagccactta tgcatttaat ggggcagata cacctgaaag
    31801 gcgagaacgt tttcgtacac ttgcggagaa ttcttggaat tacggatttt ttgatgagga
    31861 ggatcggcta acaagtcaag tcatggcgac cccttttcca gtgaattttt acggacaaga
    31921 gtacctaatg gccggcattg gctatgttgc ttcttatcca gaagcaaggg gacaaggcgg
    31981 gatcaatcag atcatggaaa agatccttga agattgccgt gatcgtaaag taagcttatc
    32041 ttatctggcg ccattctcct atcccttcta tcggcgctat ggctatgaac aatcatttga
    32101 taaaatcagt tatcaactaa acagtcgtga tgtgccgttt atcaaaaaaa aatctggaaa
    32161 aataaagcgt atggattttg aagatgcaaa agctgcaatc agaagaattt atgaacagat
    32221 gccggaaaac caacgagctg gtctgaagcg cgaagactgg tggtatacgt ataaattcaa
    32281 gcaaaaaggc aattaccagt ttgctttgca ttttgatgat aatgaggaag caacgggata
    32341 tatcgtttat cagcttgcaa cgtcttcctt tattattgcg gagtggggat ttttggatca
    32401 tgatgctttt tgcagccttg ttcgcttcgt aagttctcac aatggtgctt ttgaaacatt
    32461 tgaatattca tgcggctacg gcggtaatga tcaaaattat ctattagaaa atccatttgc
    32521 ttctgtaatg atcacacctt atatgatggc gaggatcgta gatatttctt tgtttttgga
    32581 aaattatcca tttaaaaaga gacaagctgc atttgcccta caaatagaag aagatcatta
    32641 tgcgaaatgg aatgaaggaa tcgtggaagt aacaatcgaa aatggaaaaa atcatctctc
    32701 aaaagtagaa caaacaaaac tcccaatcgt tcgaggaagt atccaacata tcacgcagct
    32761 attattaggg tatcgtaaag tggaagagtt ggtattccaa gaaagaatac aggtgacaaa
    32821 agaatatgaa gaaacgttaa gctcaatctt gccacagcaa cagccaattc ttaatgacta
    32881 tttttgataa aaaacgggtg atgacaatat ttttgtcacc acccttttgt ttttcatttg
    32941 gcatttgaag gaaaatgtta aagtaaatcc tcttttttcg taaatttgaa ttttttgttt
    33001 tcttttgttt tagggttttc ttttttgtgg tcttggattg cttctttcgt aatcttttcc
    33061 cgattttttt tagatgaatc taagcgttct gcgtatactt tttcttttgg cttatcattc
    33121 attggaaagg acctccctac attatttcat tctacctcta gtttatcatc tgttaaggac
    33181 tagtggaaac gttttgccta acttataagc tgattttttt agcagataag cttgcaagta
    33241 aaaaacaaac aagctacaat tgatttattg aaattgttcc tgtagctcag taggatagag
    33301 caatcgcctc ctaagcgata ggtcgctggt tcaattccag tcaggaacgt ataaataacc
    33361 cctgtatcct ttgcggtaca ggggtttgtt ttgtatttgt gccaaaaatg tgccaaacta
    33421 gttatcattt ttatataaac tatcgaacac agtattgatt ttttctttat cctgatcttc
    33481 aagctctcga acaatatgaa gataagtaga cattgtagtt tctaaactgc tatgtcctaa
    33541 acgtttcgat acgctaagta tatttactcc ttgataaagt aaaatagatg catgtgtatg
    33601 ccttagtcca tgcaaagtaa attgcttttc aatccctaat tcttttaatt ttttgcgcaa
    33661 atatttgctg acggcgtttg atgaaactaa tccatttttt aagttgaaaa aaacaaaatt
    33721 atgagggttt ttgatttcaa aattctcgaa taattctttt tgattgattt taaacttttt
    33781 taagagatca atcgtatgtt tatcaatgga aattttccta tttgaagttt cgttttttgt
    33841 ttttccccat tcatttaatt tataattcca tgttttatta atagtgatga tttgatcttc
    33901 gaaatcgata tcttcccatg ttaatcctag aagttcagca aatcgcattc cagtggcacc
    33961 agcaactaac acgagcatag gagaagagta ctgcgcagaa aggttttctt ctacgagttt
    34021 cattaaagat ttaaattgat cataatctaa atatttatct tcttttggct tcaatgaatc
    34081 ttttcctttg attactgctt ttctagttgg atcaaacgga attaatcctt cttctacggc
    34141 atctttcaac gacgctctaa tatggttatt aaacttaata acggtagatt ttacatggtc
    34201 tttagcatac ttatttaaaa agcgttgata tcccactcta tctaaatcag aaatcaatac
    34261 cgctggcata tatttcttta tgttcattaa cgtatcttcg tattttctat aagtgatagg
    34321 agatactgtt ccttctttat aaagttgcat ccaatcctca aagtaatctg ataataatag
    34381 atttttgcga tcccctttaa ggcctttgtt caagttatat tctaattcgt tggcggcatc
    34441 ttttgcttct ccttttgtct taaatcctga ttttcttatc ttcgtgtatt ttccgtcatc
    34501 ttttttgtat gaaatttcgt attgccaact atttccacgt ttgactaatc ttgccataat
    34561 tgaatcagct ctctttctct gatacaatag gaactataaa gaagcccatt gtttgggttt
    34621 tattattttt tgcacatcct ttttgcttgc cggcgcaagg atgtgctatt tgtcgtttta
    34681 atggtataat tggatgtgta ttagatcatc caatcagagg tgtttattat gattaaagtg
    34741 atttttaaaa gaataactga acttccagag tttagattat ttgttgatta ttggtatgtc
    34801 tggtttttta ttgttgcatt gctgataggt ctagatgtca tattagaaag aaaacttaag
    34861 taagagttga gttaataaat tgaattccta aatgagatat tttgtagccc atattttgtt
    34921 tgccgacatc acctaatact atggagctaa tcgttttttc taacagacca aaatcagata
    34981 atctatttaa gctaccatct attagctctt gtgaatagcc agacatgctg atatttccag
    35041 tgaaattttc gtttccacga ctcattaagc atgctaacaa ttgaatctca atcgatgtta
    35101 attgattcag tacaagaaga taatactcct cgttatccca tgaagcgttg ttaattcgaa
    35161 gtaaacaatt cttataaaga tttttataca tatctatttt attttgtgcc tttgattttt
    35221 ctacctcgtc atttatccct tcgaatattc caatgagttg gtccttgttc tctaagttga
    35281 aaacatcttc tggaatttga tcgcgaatgt tttctaatga ttcgtttaaa tttttgtaga
    35341 atttctcgat gcgtttgaaa cgcttctcgt ttttagaccc aaaataaagt gactgcacaa
    35401 cgccaccaat ataaggaatt gctccaatac cgccttcaac tattaattca agatattctt
    35461 ttttggttag tttttcattg ctattatcca tagttacctc ctattttgtc atttccttta
    35521 caagcattgt gactcctgat ggcactcttt tgtataggtt ttattattgt gcacaatcta
    35581 actcttagtg gggcgtggtt catttatttt ttacttactt tactattaat catatcccat
    35641 tgagcatagg atttttctat gttcgatcct cttgaactaa tttctcctgt aaaagttact
    35701 ttatcgccct ttgtaaaggt atcagcattg tttaagtcct tcgcaaaaat tacatatgaa
    35761 actttaggtg ttgcagaaat atcattccaa cttttatcat cgtactcttt gtctgctata
    35821 atggctattc tagtagtcat tgattcgata acagttcctt caaaagtata tgttttacca
    35881 ctaatatatt tagtaaaagc tgtattttgc tcagtagatg gagtaataga ataataacta
    35941 tctaagaaag caccccagtc atgattattt gtctctaaaa attcttcaaa ttgagttagg
    36001 cttttattgc tgctgttaga tgtagtagtt tgagtatcag atgatgagct ttcctgtttg
    36061 ttattgtcat ttgcctcgtt tgatgaggaa agcgagaaac ctacggtagt aaaaataatc
    36121 ccgataataa ggagaatcat aggtgttttc ttatttgttt ttttgataaa tcttacaatt
    36181 aacatgatta aacctataat aaataaaaca ataccagtaa aaccaaatat accgtccatt
    36241 aatagatcct ctttctcttt tgatattgaa tattataaac caagcaattc ttttttctta
    36301 aaatcgaatt cttcttgatt aataatccct tcatctaaca actctttata ctttttaatt
    36361 tcatctgcac ttgaaatttg tgtttctttg gaattattat ctaatataga ttgttgcttc
    36421 tctatatatt tttttaaatt ttccatttca ttccaatatt tttttgtaaa cataacggtg
    36481 ttttcatctt tcgtggccgc taatatacct ccgcgacttt cgtttccgcc tagcaaggta
    36541 aattgtatat aaccattact catacctggt ttttttaatt gtacggctga tatattttta
    36601 aaggggatag ttttttctcc tttaatacct tgattaacta aatttataaa tccttttcta
    36661 ataattgaaa tagaatcatc agttacttta atcaaggttt ttcctggaga ttttattaaa
    36721 atctcttttt ccattttttc ttcctcattt ctgtgatatg attttttttg tagaagctca
    36781 tatatgagga aagagcccgt gttgcagcac gggctttttt aatgttttgc tgaaatcggt
    36841 ttttttaata attcttgatg tattcataca tattgccttg cgtaagaata ttttttctta
    36901 aaatagcatt ggcagacagc ataacaagtg tatctgagct tattctgaat agaataatac
    36961 tccataaatt tttcgagatt aaactgagat tcatcagtca gttcgttctc aatatagata
    37021 tttaataaaa ttagaatagc tattttatct gcttctgttt caaattttga gtgaaaagtt
    37081 gtagaagtat cgtacaaaac tgaaaattca aaatgagagg cgctgaaatg tgcaagttca
    37141 tgagataaat gaaaggcttc tgcagtttca ccgtatagat tttcattcaa aaaaatgatt
    37201 ctgggttttg gatagtagaa accaggctct ttcatctcca tataaactac tttcaaattg
    37261 tattcgctca acatttcttt caatttcaaa tacatacaaa ccatcactcc aactattcat
    37321 tttcctctaa agctttagca attgcaatcg ctttacgcat tgtctcctta gatatttctt
    37381 ttccatcaaa agaaaaaaca gtatcgtctt ctgataaatc cacatgttta ggggtttctc
    37441 tttcttctct acctagaagg tagtctacag agacatcgaa atagtcagca atccgactta
    37501 attcatctga attaggagta ttatttttcc actttgctag ataaccgtta gaatatccaa
    37561 aattaatttc taactgccgt atagatatct ttttcctctt cgccaagtct tttattattt
    37621 cataggtatt catcgataaa acaacctttc taaatgttta caaaaaaagt ttagaaaaat
    37681 acgcagaaat aatttgacta attctgagta atgagctata ctatatcttg taaacagatt
    37741 taacaactaa aaagacaaca aaaaacacta ttgatatgta aatgcagacc gccaagaaag
    37801 ctttaaaatc aatgttttta tgtcttattt aattatgctc ttagtataga gtattactca
    37861 gatactgtca attgaattta gaaaaaagtt gttaaatttg tttacgaata taaaagaaag
    37921 gaatgagaaa tatgaacaca ccgcaaattt ttaatttcga acaaaacgaa gttcggacaa
    37981 ttttagtaaa tgatgaacca tattttgtag gcaaagacgt tgcgagtgtt ttgggttatt
    38041 caaacactaa agatgctttg tcgcggcatg tagatttgga agataagatg gggtcgcgaa
    38101 tcacgacctc aggtcaatca agagagatga caatcatcaa cgaatctggt ttgtacagtt
    38161 taatcttaaa atcaaaactt ccctctgcca aaaaatttaa acgttgggta acaagtgaag
    38221 tgttgccagc aattagaaaa catggaggtt atctaactcc agaaaaagta gaagaagctt
    38281 tgcttaatcc agatacaatc attcaattag caactcaact aaaagaagaa agaactggaa
    38341 gattaatcgc agaacaaaag attgcagagt acgaacctaa aatctcctat ttagatagca
    38401 tattatcttc tacagattca gtaacaatta gtcagattgc agcagattat gggatgtctc
    38461 cacaacagat gaataaatta cttcataaac taggtattca gaaaaaagtc ggtaaccaat
    38521 ggttattgtg caaaaaacac atgaaccaag gatacacaaa atctcataca actgagatcc
    38581 cgaaagccga tggtggcact aaaattgtaa tgaataccaa atggacacag aaagggcgtc
    38641 tatttatcta cgaattacta aaaaaagaag gatattaccc tcaaatggat ttagaggaaa
    38701 ttggttagaa aggagtttta gtatgactga cattgcagaa atcactcaac gagatagaga
    38761 aaaaatcaaa gaatatgtcg aaagttcaaa gttcttaact tacaccatgc ttgctgaaag
    38821 atttggaatt agcaaaagct acttatcttt aattttaaac ggtaaaaaga cttctgcaga
    38881 agcaaacaga attatagatt cgattatcac tatgtacgaa ttgtaaaggg aggaacagct
    38941 aatgcaatat ctagaagcaa aaatcccaat tccagaaggc tatgtaatta tctcccaagt
    39001 ggattatgag gagttaaaaa aagctgatga tactggtaga tggatgacgt tgccagaagt
    39061 gctagaacgg attaacagaa aatatgattg gtttacttct agagttttaa agaacccaag
    39121 atatagaaat attatcgata tcgagaaaaa caaaaatgga tttgtctatt atccagttga
    39181 aggaagagac acatatctat ttttaagaag taaaacactt gaatttttag aaacaaattt
    39241 ttcggaaatc ttaaggaggc aagcggatgg gaaaatttaa tagagcgcta gtgttcagcg
    39301 caccgctaat catctacgct ttagaacttt ggggaagcag gcaagcgttg ataggaacga
    39361 ttgtttacat ggtttggatt tttatggggc ttgatgaagc tgaagctgag tacagagcga
    39421 aaaagccaac cgagggggct gactaaaaat gaatagaaaa gagaaactag aatgtatatt
    39481 actattactc agtttaattc tttcactaat ttctctattg ggaagtttgt atttttgata
    39541 tcaacaattt tgtggatttg ggttctattt agagtaaata tcatttttgt ttggtgatta
    39601 aggagtttat taaaattaat tttccctact tcaaatgcaa ggtaacaaga tatagcactt
    39661 ttaggaggaa tatttagcgg tacagcttca gagtatattc tattatcatc gactgatcct
    39721 cctttagcaa ttaatttctt aaatggagta gctgaccatc tgcggtttaa gttagcggat
    39781 gaaagttcta aattaactaa catagctggt tctgttgaat agttagaaat gattactttt
    39841 gtataaatca tatctgcagc gaagtaagaa gcattaagtt caacttctag ttgagggcgc
    39901 attcctttta tttttatccc tgttaaaaac gtactcaata taaaacttat tattgacatc
    39961 cattgaaaaa ttgttaagtg aaaaaaattc aaaataaaca ccaccagttt ttaactaaat
    40021 tataccaaaa aggagagaag aaataatgca agaattagta attttgaaaa ataaagaagc
    40081 tgtgactacg agcttacaag tggcagaaag cttcgagaaa aaacatcaac atgttttaag
    40141 agatattgat gcactaaaaa aagatgtgtc caattttgga cagatgtttg tagaaggtaa
    40201 tgaaccagat tcatatggca gaaatcgacg agttttcttc attagtagag atggattttt
    40261 cttgctggct atggggttta caggaaagaa agctatctac ttcaaacaaa aatacattga
    40321 agcattcaac gaaatggaag atgttattcg caagaatact gttcctcaaa caattgaaga
    40381 tatgatgatc tatcaattag aagaaatgaa agatgttaaa aaagatgttt ccatgcttaa
    40441 agatactatg cgaattagcg gacaacaaga gtttgaaatt aagcaaaaag gaaatatgaa
    40501 agttatggga gttctagggg gaaaagaaag ccgagcttat gaagaaatca gcaaaaaagt
    40561 attctcaaaa ttttggtctg aatttaaacg taccttttca atcccaagat atggcgagtt
    40621 acctcgtaag agattcgatg atgctgtttc atttattgaa atgtggttgc cagaaactgc
    40681 gatccgtatg gaaattgatc aactgaacag acaacagaga ctttttggtg atgacaatga
    40741 atagagctga agcgctaaga atagggacgg caattgctaa ttgctggtgg aaatactata
    40801 aaccaatcat cctaagtcaa caacatattg acaagcaaaa agcatggcaa caaataaaaa
    40861 agtgactccg ccggcaagca aagagtcaca aagaaaacac atcataagga gattttagca
    40921 tatggaaaaa gaactttcca ctctagatca atatttgatt gatcctgatt ggggcaagcc
    40981 gaaaattgag gaaacaagtg gtcgaaaaat cagacgaaat cttttgacga atgaagaact
    41041 agcttgggat caagatgatt taggcaacca tgtaactatt tgggatcatg tttatcttat
    41101 ccatctatcg aagcattcga ataaacctga atatatttac gtcatcgaag atggcttgat
    41161 tgatgcgcta gaagagtacg acagagataa cttgattgat atctcttatt acggaccagg
    41221 taagaaatac attgctgaaa tggaggcaga atttgatgag tgaaatcaaa gggacaacga
    41281 actttgaaaa actttttagt cgtaagttaa ataaaattct caagaaaaaa ggaaattttg
    41341 attatttatc ttgggctcac gcgtgggaga ttatgaaaaa gaatgatcca caggcaacgg
    41401 taactattaa tgagtacaaa cactacaggg ttgtttctgg aactcatcaa gactttcttg
    41461 ttgaggaata taaacctttt cttatggatg aaactgggac ttatgtatct gtctcagtaa
    41521 cggttaaagg acacacggaa accgaattat ttcctgtttt agattatcga aaccaaccag
    41581 ttgttaaacc aaatgcaatg caaatcaata actcattgaa gcgatgcttt gtgaaagcat
    41641 tggctctaca cggactggga ttatatgtat ttcaagggga agatattcca acaccaccta
    41701 gaatcgatac aaagaaatta aacatgctag agacgattct agaagctttc aatgagcaga
    41761 tgggtaaaga tatgaccaaa accttaatcg aatatgttaa tgagcagaca gataaattag
    41821 ggctcttagc tgataacgtt gaaactattg aacagttaag ctatgagcaa tgtgccttga
    41881 tggagcgagc aatagcagct aagagaaaag aattagataa gaagtgatat gagtgtttaa
    41941 accattaatc gattcatatt cagcggttct gaaaaagttc aaaggaaaag acataagcgc
    42001 aaccatcaat gaggaagtga acattgatcg actaaagacg atgtatgacg gctacgatgg
    42061 tgatcgagtc attgaaattc gttttattga tcctagacgt ttcaccgtac agcaacgaaa
    42121 cttcatctat gcgctgatag gcgatatttt tatcgataca ggcatgccaa cggacttctg
    42181 gaaggaattc ttctactttc gttttgaagg tgtcacaggg cgcaaaataa gcctgaaaga
    42241 cgaatcgaat acaactgtga gtgatgccaa tgtcttagca aatatcatct tagatttcat
    42301 ctttgaacat catattcctt tcaaagaagg ctatgagatt ttacctgcga atcaagaata
    42361 ttacttctac aaatgcatca caaaaagagt ctgctgcatc tgtggcaaaa caggagctga
    42421 catcgatcac tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcatgcaga
    42481 gtacacattt gcagcactct gcagaatcca tcacacagag aagcacaaaa taggtgtgat
    42541 taatttcaaa aataaatatc aaatcaaagg gatcaaatta aaccagaaaa caatcaaaaa
    42601 gttaaatatt ggagggtaaa aatgacagaa catcgaagtt attatgcgat tataccagcc
    42661 aacgtaaggt acgacaaaag acttaaacca aatactaagt tgttatacgg agagataacg
    42721 gccttgtgta atgaaagagg cttttgttgg gcaggcaatg agtactttgc agatttatat
    42781 ggtgtgaata aagagaccat atcgcgatgg gtaagtgatt tgattaagtt tggatacttg
    42841 aatcgggaaa tcatttacaa agagggtacc aatcaaataa tcaataggta cctacgaatt
    42901 aatcaatacc ctattgacga aaaacgcaat acccctattg acgaaaaagt caaagataat
    42961 aatacatcta ttaataatac atttaataat acaaaagaat atataagaga gttaccgcct
    43021 tcgaaaaaat cgaaggctaa gcccgtccgt cataaatacg gagagtataa aaatgttctt
    43081 ttgtcagatg agcagatgga gaaactcaaa acagaattcc ctaatgatta ccaagagcga
    43141 atcgaacgac tgtcagagta ttgtgaatca tctggtaaga cttataaaaa ctatttggca
    43201 actattcgaa gttgggcaag gaaagaaaaa agtgaaccta agaacgcaag cagtggatac
    43261 aagcgcacag gaagacgaga gaagcttcct gaatgggcaa tcgaccaaga agcctatctc
    43321 aagaaaaaag cgctagaacg agctaataga caatcaaaag caccattcta agaggtggaa
    43381 aaatgaagat cgattatcta gaactaatta atgaaatagc gaattataaa aagggcgagg
    43441 aattagacgt cctgagagac gtatatgatc aactcgaaga agctggaatt gaaggaatta
    43501 agaatgatcg ttcgagttgg agtaagctca gatactattt cgcactttat atcgatacaa
    43561 cacaattaag aaatttagca tataccaaat tactatttgt tgattgtgtt aaaggcttgc
    43621 aaaaacatct taatgaactt gagcaggtgt aatcagatgg acctaaagac atttacagca
    43681 cagattgaac taatgcatca agaagcttta agacaaagtg tatcgtacga agacaagtgg
    43741 ctcaacacgt tccatggcgg acgtgagagc gcacttgatc aagtactcaa attactgaaa
    43801 ggagaatgtc gggatggata agaaagcggc aatgcagcga attatcgaat tgacttattc
    43861 agaagattgg caaaatgaca aagaagctgc ttcagaagtg atgaggcttg gaagagcgat
    43921 gtgggcagac aagagcaaca agccaagacc acgaaaaatc gcaatttggc acggtgacaa
    43981 acttctagtg atagggacag ctgaacagtt agcaagtctc acaggcttgc acgagaaaat
    44041 cgtgaggaaa agagcaaggt gtggctacac agacgctaag aagagaacgt ttagatacgt
    44101 ggaggaatca tcatgacaac agaagaagtg attcaaatgc gtattcgaag ccttcagcgt
    44161 gagattgacg atctggaacg aacaaaggca gtgatggtca atgaaacggc gagaaaggca
    44221 atcgatttgc acatagagaa tttaagaagg gaaatccatc gattggagga atgagcgtgg
    44281 ataagaaagc agcaatgaaa agaattgctg aattaaccaa gtcagaatct tggcaagaag
    44341 acaaagaaat agttgcagaa gtccaaaagc tcggtaaatc aatgtggact gaaaagccca
    44401 aacggagaac gccgagaaaa attgcaatct ggcatgatga ccgaatttta gtaacaggta
    44461 ctgctgaaca gttatctgaa attactggat taagcaaaaa cattatctgg gatagagcta
    44521 ggagcttatg gattgattca aaaggacgac agtttaggta tgtggaggag agataatgga
    44581 tctcattaca caatacagtg acatcatcct caagaaaatc atgatgaaga ttcagaaaga
    44641 taaaaaatca aaagaacgag ctgaattagt taagttagaa atggctgaaa caggagcagg
    44701 agtgcgaagt agcaggcatt ggaaagcagc agcaaacatt gaattttatt acaacgaaat
    44761 tcaaaaaggg ttcgatcaga tgcgtgagct ggatcggcaa acaaattgga gcaagaaact
    44821 tcatcaagat cgtttcaaat ttgtagagaa gtataaagaa atattagaag agtatttgag
    44881 gaggacagca aatgataaaa aaactcgttc aattcagcat ggatttatat gatatcgaat
    44941 caggagcaac actatctgtg gaatcggacc atctaatcat aaattttggt ggaaagcgcc
    45001 agattatttt gtgggtagtt gatgatgtac tgtttccaga aattgttcat gatttcgaag
    45061 aatcaaaagc ggttgagttt gaaatagtga aaaaagtaat ggaattgatt gaaaaatacg
    45121 aggaggacag cgaatgatac cgaagtttag agcgtgggat aaacgaaaga acgtaatgag
    45181 agatgtagcc gtcttgcatt ttactaaaaa cggcaaaaca aactttattg aatattggat
    45241 aaatcctacc gaattgaaat catatcacgt gcgaaacatc gacctcatgc aatccacagg
    45301 aatgaaagat aagaatggtg tggatatatt tgaaggggat atagtattag tcagcgtgcg
    45361 aaatggcttc gattacttag ataataaagt ctgtattgtc aaaaattcaa tagattattc
    45421 cggattagtt tgtgccactg ttgatgaaga cttagagtat caaattttta acacagagct
    45481 gtttgaagaa tacacgtacg aagtcaccgg aaatatatac gagaatagcg agttattgga
    45541 ggaacagcga tgaataaaca ggaagcaatc aaaaagttag aaagtattaa agcgatagga
    45601 aatgatgcaa tagctgcttg ctataacgag agtataaatt caggtattac gttaatgaaa
    45661 aaaatagacg aaccgcagaa accagttatt ccacaactcg tggccggttg gcttgagaaa
    45721 tctacggacc cttttacaaa agctgaaaaa atagcgtatt taatcaaatc taaagatggt
    45781 gattcatatt atttctgtga ttggtttgta cgagatggca tagtgacgca agagcaagga
    45841 gaagaattac tcgcttgggc aacaagacaa tcatatgaaa cactattgag cctatacaac
    45901 ggctacgagg ttgagaaaga gccgttatgg gcaataaaga atgccgatgg aaactatctt
    45961 actaaatgtg ctttatgggg aaaagatgga gtaaattata gttttgaatg caatccatct
    46021 catcgattgc ttttcactga taaagcaaca gcggatgctg cagcattgtt ggtgaatgga
    46081 acagtggaag aggtggtaga aagatgaaac taaaagacgg attttacgct agcagtcacg
    46141 gtatcggcgg tttaatgcta gatatgccga caaagaaccc taaaacacgc aagaaatcaa
    46201 aattcaaagt cggtgacatg gtccgctgtg aagcagaaga gttcgtttat ccgttcagag
    46261 gatacgttaa aaagatactg tcaaactcag caatcattcg tattgaaaat acaatgaagt
    46321 gtgatcgttc gactgcaaaa cacaagcatt atttagctgt agcgagatta gttgacatgg
    46381 aagtaatcaa gagcaaataa aaaaagccgg atcgctccga ctgattcaat aaatccaaca
    46441 catttattat atcacataaa ggagcggttt gacttgatgc aattgttacg agaggtagat
    46501 ttcaaacaga caagatgtaa tgcgagagat gtgctgaaga actttcggcg tttggagcgg
    46561 atggcaggtc gctctttgat agatattaag tcgccgatta taacggatat gccgaaggca
    46621 ccgaagcatg gcaataaggc agaagacgcg attattcaga tgatggatat agaaacggag
    46681 agagatgcga ttctagcggc tttgatggct cttagtctga ttagtcgtca gatactctac
    46741 tacagcttct gtgtgccaga tagcttctca aactacagaa ttagccgtga agtgggttat
    46801 tcagaaagaa gtatacaacg gatgaagtcg gaagctctaa tagagtttgc agaagcatat
    46861 aaacacggaa aaataattgc ttataaataa tttggcggtt ttttggcgga atgatggcgg
    46921 tttttagaca tttaccagtg ttattatggt agtgtcgaaa gattaggaaa caggatcgac
    46981 aaaataaacg aagggaggca atctccctca tcgttttaaa cttcttctta gatagacagc
    47041 aactaattat gaagaaaagg atgtgaattc aactcctcct aaattcttca tcggttgctg
    47101 tttattttga ttagacagca gcactcacaa aactaaacat gttcttgtcg tctttcaact
    47161 gctgctgtct attaatttat gtattggagg gaagaaaaat gaaattatca gtagaaggca
    47221 ctccagaaga aatacaagaa ttgctccaag ctattggtag tagcaaggag caaaaggtaa
    47281 gtgtttctaa ttcagatatt gacggtattt gcaattgttt aaacagagaa aaaatatcta
    47341 atccttacta agagaaaata tgttcgttaa tgaatttcca attttcctct gtagctctac
    47401 cttgataatt tttttgcagt tcacagatga ataaggaatc gttattatca agtactgtat
    47461 ttaatttttc acacatttga tttggattca aattagtttt aactaaccaa aaagattttt
    47521 gtagctttat atatgcccca aattctttta ttatttcaaa tactttatca tacttttgcc
    47581 ctgggttatt aagatcataa ctaatcatgt agggtttata catgttgtct tgcacatcct
    47641 tgttttatat ttcagcggac cactcgctga taaataaaat tatacgctta gtatttattt
    47701 tcacaatatt aatttatcgt aataactttt gagtaaatag aacaaaaaac ctgcactagt
    47761 ttccgctagt acaggcagtg actatatcgg ttgataatct agcatatatt aaaaataatt
    47821 gcaagaaaag aaatttatag tggtttatac caaattatca aagcaatgtt attttgttgc
    47881 tgtctattgt tttttaatta ttcacacgat aactaaaggt gggtgaagag aaatgattcc
    47941 attaataatt tcaatttttg cgctctgtct taatgtctat atgattggat ttaaaaatgg
    48001 gcaaaataaa aaatagtagc agccaagaat aattttatag tgtcactgtg gcggaaaggg
    48061 tagacgctaa gcatgtgtgc taggtcaatg cttcggcaac catgcaaggt tcgattcctt
    48121 gccagcgaca ttaaatgcct atgacggtta cgactaccga aaaaagatcg ttaagaagct
    48181 atacggtgct acgtacggca atgtagtaag tgtgctatct gtgtacacca ccaagcttcg
    48241 gtcactgtgg cggaagtaga agacgcagcg gtaaatggcg agtagcctcg tgagagcctg
    48301 gtaagttctc gtgagtggtg caatcccact ccagcgactt taagcaaccg aggcatcggc
    48361 ggtttaaaaa tataggggtg cgcaatttcg tacgcgtttt gtgcatcgtg caagttacta
    48421 ttacatatta gatcactctt tgagtggtct ttttattttt gcacaaagga ggaaacaaca
    48481 atgtatagac cacaatactt agaacagaag tatgaagtaa tcactgttca taaaggtaat
    48541 ggcgaaaaag tatatgagta tagaagacca ataaagagcg atacatataa acgaaaggaa
    48601 aacaatgaag ttattccatt gtatggcaaa agaatagcta agcattaaat aagattgcga
    48661 aaggagacgg aacatgaccg aggaattcta tagatggcta ttacagttga caagagaaga
    48721 tcgtttggtt aagttctatc agtctcctaa atggcgcagg cttagagaga aagcgatgaa
    48781 acgagatcac tatgaatgcc aagagtgtag aagactaggt aagtatcata gagtagagaa
    48841 cgttcatcat ataaaggaag tcaaggatag acctgactta gctttagatt tagataatct
    48901 tatttgttta tgtgttgaac atcataatga agttcatggc agatatctta cagcattaga
    48961 taaacaagag aagaagatag aaagctttgc taacttcgat gcaagtgaaa ggtggtaagt
    49021 gcatgatcat caatgataat ggcagagagt atgatacaga aaagattgaa gagtattcat
    49081 cttatactca gggattaatt aaacgtttga tatacgttcg ctatgtaggt attagggatc
    49141 tgttatcaga taactgttgt agtaaataca aagtgaatca agtaagagaa gcgttgaata
    49201 aagataataa cgtcgaaaga ataaaaaatg tttttggata tagtattgaa gagattaatt
    49261 attacattga cttcgctgaa gctttcattc cgatggtgag ataacccccc cttaaaataa
    49321 atcgcaaatt ttttgggggt gatgaaacgg agggggctgt caggaaaaga gattttttcg
    49381 aactttatca tgaaaggagg gctaaaatgt ttaaaaacga attgtctcaa aatcgctaca
    49441 gagaaaaatt acgccgctct ttaataagcc aattggaaag tcagaaaaca aatattgagc
    49501 cattcttaga taatgttgat cgttatatca gtttatggga aacggcgata tcactggaag
    49561 aagatatatc cgagaacggc attagactgg agaatggtaa aaagaatgaa tcagtagcgt
    49621 tgcttgtttc tgtcaacaaa caaatgggat tgatgttgga taaacttgcc attactcctg
    49681 aattggtagg tgaagcaaat gaatcaattc ctgagttata agcatattga aaattggttc
    49741 aaagctatag aagaaggcac tatcaaggta tgcaaagagc aattattgct aaaaaattat
    49801 ctagaagaaa gagtctttac tagagaagat atttacttcg ataagcagat ggtagaggat
    49861 tcaatcaata taccagcaca atactttcca ttcgaattaa ttccgtggga aaaatttcta
    49921 caatgtttta tttatggtgt tcgatggaaa aaagataaaa cactagtgtt caatagatat
    49981 ctttcattaa tgggacgtgg taatggtaaa actggttttg cttcttggaa caacttcttt
    50041 ctactaaccg ctaaacacgg tattaaaaat tatgatattg atatctatgc caataatgaa
    50101 agccaagcaa agactagttt tgatgatgta tttaaagtaa ttaaagatca tcctgattta
    50161 gataaaaaag tatttaaagc tacgaaggaa gttattcaaa atatcgctac aaacagcaaa
    50221 cttcgttata acacggcaaa tgctagaaca aaagatggga agcgaccagg tgcaaaccgc
    50281 tttgatgaaa ttcacgaaaa tgaagattat tcaatgataa atgtggctac ttctggtggt
    50341 ggtaaaattc gagattatag agaattttat gatacaacta atggtcatgt tcgtggtggt
    50401 ccgcttgatg acattataga agaatcaaaa atgattcttt ctggagaact tggaattgac
    50461 aaggatggag cagaattttc tagtttgttt ccatttattt gtcgcttgga taacgataat
    50521 gaagttgatg atcccgacat gtgggaaaaa gcttgtccaa ctattaatta caatgcagat
    50581 ttaaaacgga aaatgtttca agaatactct caaatgcaac gtaatgctgg tttaagactt
    50641 acgttcatga ccaaacgaat gaacagacct atggaagata cacgatttgc tgttgcttca
    50701 tatgatgatg ttctgcatac gaaagaaaaa gaatttcctg aaaaaatgga tgaagtgata
    50761 ggaacagtcg attttgctga tagacgagat tttgccagcg ttgggttgct aggaaaatac
    50821 gataaagatg tttattttac acaacatact tttatccacg aatcagccct tcgattacaa
    50881 aacatcaaac gagaggttat agatatttct atagatcaag gaaaatcaca gatcgttcat
    50941 ggaaaaaata tagaagctga ttatattgta ggttggtttc ttgaaatgag taataaatat
    51001 tatattaaaa aaatcgctat ggatatgtac cgtgcaaaaa tattgaagcc cgctttagaa
    51061 gaagcaggtt ttactgtgga aattgttcga agcggatctg ttacacatgg tatgttaaaa
    51121 gatctggttg atgacctttt tattaatcaa cgtttatttt ttggtgacga tgcgattatg
    51181 cgttggtatt gcatgaatgt atatgaagag catatttcta atggaaatat acgctatgaa
    51241 aaaatagaac ctgaaactag aaaaacggat ggcttttttt cattccttca tggtttgaat
    51301 tttttagatg atatttatga ttctgctcct gtaacagtca caaatagctc agtagaaaat
    51361 acaggaactg gatttactcc tctagtattc taacttgaaa ggaggtgaga aagtggggat
    51421 ttttcaaaag gcggtaggat acttcacaaa aaaagcaacg gttcctttag aagaatactt
    51481 ttgtaaattg caagttgatt ttgtgtatcg aaaatttgcg attgaaactt gtattgattt
    51541 gattgcaaat gcgatgagta aagcggaatt caagtcatat gaagatggaa aaaataaaaa
    51601 gaatgatctt tactataggc tgaatgtagc tcctaataag aaaaataatg caacagaatt
    51661 tagaaaaaaa ctgatcagga gattaatatt ctacaatgaa gtattgatcg tttctccgtc
    51721 taataattct agcgaaatat ttattgcgga tagttgggat gtcacagaat atgcattgaa
    51781 agatgatgtg ttttctcaag tgcaaattaa caacatagtc cttgatagag aatttctaga
    51841 aagtgatgtt atctatataa aatacgcaga tcaacaaatt aggcaactag tcgatgcgta
    51901 ttatcaagcg tatgggaaac tcatttctag tgccatgaat gtttacaagc gctctaacgc
    51961 tcgtagatac gtactgaaag ggaatttatt ccgaccgcaa gacaatacaa cacaagatca
    52021 aatcaataaa atgatgacat cacaatttaa ggcttttatg gaagctgata atgcaggtgc
    52081 ggtatttcaa ttacaaaatg agtacacatt agaagatttc agcggaaact tccaaagcaa
    52141 ttcaagagat ataaaaaact taatagacga catctttgag atgacagcag cagcgtttca
    52201 cgttccgaaa aacctactaa agggagacat gagtgggtta tcggatcaag tggacgcttt
    52261 tttaatgttc gaaatcatac cgattgctga acttattcag gatgcgttta acgctagtct
    52321 ctatgaagta gaagaatact tgtcagggaa ttttgtacgt gtggatacaa ctatgatcaa
    52381 gattactagc ttcaaagatt tggttgacgc tattgatgta ggcattagaa atggagtatt
    52441 tacaatcaac gaaggaagag aacgcgttgg aaatgatcgc tctgataagg cgatggcaga
    52501 tgaaatattt ataactaaaa acaatcaaca agtatcgaaa ggaggtgagg cgaatgacga
    52561 caatgaaaac atttctagca gtaaagaatg aaggcgcagt accgcaaatt tttattcagg
    52621 gatttattgg ttctagttgg ttctttgaag ggaatactga caagggaatc aaaaatattt
    52681 tggatagtct aggtgatcaa gaagaaattg aagtagtaat taattcaaac ggtggagacg
    52741 tatttcaagg gattgctatt gggaacttac ttaagtcaaa taaagcaaaa gttaacgttg
    52801 tgattaacgg cttagccgct agtgctgctt caattatcgc aatggctggc gatactataa
    52861 aaatctacaa caatgcacaa ttgatgattc accgcgcttc cacatacgga gaaggaaatg
    52921 tcgatgactt ccgtacgatt gctgaccaac tggaatcaat tgataaatcg gtaaaggctt
    52981 catataaaac acgattcaat ggcacagatg aagcattgca agaacttctt gaaaaagaat
    53041 cgtttatgga tgcagaaaca gctttgagtt atggattggt cgatgaaatt atcgatgcag
    53101 aaaatagctc aggtactgaa gctaaaaaag aacaaagcgt tgaagaaatt ttgaatgacg
    53161 ttaaagaaaa aagagcagaa aaaattgctg catttacagc agcattaaat aaaacatttg
    53221 gacaaggaga tgtaaaataa tgacagttaa aaatttaaaa ggtgtaacag ctgcaagcga
    53281 ccaattgatg aaagctttta aagatggtaa cgaagaatct tttagcgcag ctatggtaag
    53341 cttatctaag gaaattcagg ataaaatttt agaagaagca acagcaaaaa atcaagatca
    53401 attagtatta atgaaccgtg gtcagcgtgt attaactaca caagaaacaa aattctataa
    53461 cgaagtagtg aaaaacgaag gttttgcagg ggtcgaagaa ttagtgccag ctactgtatt
    53521 tgaacgtgta tttgaagatt tagaacaatc tcatccacta ttgcaaaaaa ttacttttgt
    53581 taacacaact ggtgtaacag aatggattgt gtcacgtgga gtcaatccag catggtgggg
    53641 taaactttgc gaagctgtta aaaaagtttt agataatggc tttgatgtaa ttaacatgaa
    53701 gcagttcaag ctatcaggtt atattcctgt atgtaaggca atgcttgatt taggtccagt
    53761 atggttagat cgttatgtcc gtactgtttt agtagaatca ttgagaattg cattagaaca
    53821 agcaattgtt gatggtactg gtaaagatat gccagtcgga atgatgcgtg acatgagcaa
    53881 acaaactagc ggagaatatg ctgaaaaaaa agcagaacct attacagctt tagatgctgt
    53941 aactatgggc ggtttgatgg cgcgactatc aaaattcaat atcgaaggtg tgaatgatcc
    54001 gatttatcgt aatgtgaatc cttctgatgt ggtcctaatt gtgaatccaa ctgattactg
    54061 gtctaaagta ttcccagcta agactgtact aactgctaat ggagaatacg tacaagtatt
    54121 gccagtacca gtttcagatt tgcagtcaac ggctgtgcca gaaggaaaag cagttattgg
    54181 ggtagcctca gattacttca tgggtgtagg atctacacta aaaattgaag cttcagatga
    54241 ataccatttt gttgaagacg aacgcattta tctagctaaa caatatgcaa acggtcaacc
    54301 taaacgtaac gatagtttca ttgtattaga tattagcgct ttgggaacta ctactacaac
    54361 tacaaaacca acaaccacaa caactacaac acaagcgtag gtgatcagaa tgaagtatat
    54421 tctttgtcag ccggcaatca atcggtttaa atgggagctt gaagtttgtt taactaatct
    54481 gaagaaacta ggaatcaaag atatcgtatt gcttttcagc agacacgatg atcagattcc
    54541 tatttttttt gagaaggaat atggtgttga agttcatgtg tacgatgatc tgcgggacga
    54601 caaagagtat attccttcga ttaaaccata tttatggtgg aaatatttag aagaagatca
    54661 ttcgcgtgag gacgaccgat atttctatat cgattcggat gtcattttca ataaaagaat
    54721 taatttgcgc aaattgcctt ctaaagatga tgtttggtat tgtagcgact gctgtagtta
    54781 tctaagtctt gattatatta gaagctgtga aaacggagaa aatattctaa aagatatggc
    54841 aaacattgta aatgttacag tagaatcttt ggaaactata aacactaatt caggaggcgc
    54901 acagtgggtt attaaccgtc ctaaagcgaa ttattggaaa aaggtttatc tggattctaa
    54961 tcggctatat cgctacctta gagggcaaaa aacaaatata caaatctgga cagccgagat
    55021 gtgggcacag ctttggaaca tgatgtattt caatattggt cctaaagttc acgaggaatt
    55081 agacttttgt tttgctactg atccaataga aaaagttaaa gaagtaaaaa tcttacacaa
    55141 tgctggagta acaacaaacg atgaagattt atttttcaaa gggagatacg tgacttctac
    55201 gccttttgat gaagatttat catttgtaaa caagaaaaaa tgctcttacg catatgttaa
    55261 agcaattaag gcggtggtta gatgacgcct gaacaagtga ctgaagaatt gctaatagct
    55321 gtgaaggata atatttacgt tacctggaac gaagaagatg agtcaattaa aaagatgata
    55381 gctaaaaatg ctgtttatct tcaaagtaaa gtgagtacaa cactttcttt ttctcctgaa
    55441 agcttagaat acggattgct aatcgaaaga tgtagatacg actggaatcg tgctttagat
    55501 gagtttgaac aaaatttcgc tagtgagtta ttaggtttca ttcaacatta tgcgctacaa
    55561 gaatatattg caggtgatgt gaatggcgaa taatcgtaga ctcgaagaaa cattcaacga
    55621 tggttggtta aagattttga cgcaaactac caaaagaaat gaactaggaa aaaagattgg
    55681 tgtagaagat acagaaatca cttctttaaa atttagaaat ctttccatga gagatagtga
    55741 tataacagct atggatgcga tgggatcgaa attaactaag aaagtaaaga ctccatttca
    55801 tccaatcgcc aagaaattta ataaagatca atattttatc gtaatcgata gtatgcgtta
    55861 caacgttatc tatgccgatt acgataattt ttatatctat ttttatcttg aaagtgtggg
    55921 tgaatatggt gattgataat tctaaagaaa aagaacgttt aaataagcaa atttctgcta
    55981 tcaaaacttc cttagaagag cattttggcc tcaaactctt tcaagactcc gtaggcgagg
    56041 atgagctacc tgatgatttt aattacttca ttctcgaaac aggagaaata gaaatgatca
    56101 ctgagccaaa atatagcgtg ggtcaaaatc tatatctaac tttctattca gaaaatagag
    56161 aagatttaac aggagactca ctagatatta tttcattgat tcaaaatcgt tcgattcgtt
    56221 ttcagagaat ggatcccaat catttaaaac tagagaacca agatcgctat atcgatcaat
    56281 tggtatttac gtttagacga ttattgaaga gtgattgtca tggctaaaaa tagttgggag
    56341 ctaaaaataa atggacatga tgaacttctt gtgcggatgg aacgctattc aagcgagagc
    56401 gaacgactga ttaacgaagc attgaaatca aaaggttcgg ctattgcagt ggataggatt
    56461 acagaaaaaa ttcctgtttc tgaagcagat ttaagaagag ggcaccaaca cgcaaaaaat
    56521 agtcgtccac ttaagactca atacattaat ttgggtttca tcattagacc tacaagaaaa
    56581 tttgagtatt taaaatatcc tgatttgggg ataggtactt ctaaaagaaa tcagccggac
    56641 gaatttatga gaagaggatt aggtcttgca cttgatccaa ttacagaact tctgattcgt
    56701 caattcgata aattaaataa atagggggaa caacaatggc taaaacaaaa actgtagtaa
    56761 caacgttcga taacgtaagt atcaaacgaa ttgcttttaa ttttaagaac gcaggaaatg
    56821 caatcgcaac gaattgtaat ggacaattag atggcgaaac agaaatgcaa acggtggtta
    56881 aaaaatgtgg agcgacagaa gtaaaatcaa aatctaaacc aatcaatatg acggtaacaa
    56941 ttactgcaca tgtaccgatg gaagtttatc gacgtttcaa tgggttgaaa caagatggac
    57001 gtattaaacc aggcatttac tcttacggtc ctgattccgt aggcgaagat ttctcacttg
    57061 ctgcagagat cgtggatgac ttcgaagaaa atagaaagtt agttggtatg ttagcatgca
    57121 cttcgaatac aggattaaca ttctctattg aaaatggtgc ggatgaagta gctgcgttag
    57181 aactagaaac aaaagttatg caagatgaat ttggtaaatt ttatcatgaa gcaattgttg
    57241 cagaacttga agaagactta acagatcaat ggatgacgaa tctatctgct gatgtgatta
    57301 aaaaaacttc agttgtgaca actacggcca ctcaatcaca gtaaaaaaaa cggaggtagc
    57361 gaaatgaacg aagattactc aaaaattgaa ctaaacgatg gaacaatttt gaatttagaa
    57421 cctaaactga atatcaagaa attattgatg atcaatagag attttaacac agacgagttt
    57481 gcaaaaatga ctgtgggaaa aggatccatg gatatttctg ttattcaagg tgcaaaggct
    57541 gtgtatattg cttaccgcca agcgaacatg actgattata tttcattcga tgaatttatc
    57601 gataaatggg attttgatat ggctactgcc agctatattt atcaattgat gatgttcaaa
    57661 caagcacgcg atgcttatca aaaagaattt gaaaaagcaa ataaggaaaa aaagcttcaa
    57721 aagtaaaaat tccaaagctc ttagttgaaa cgtgggtcga tgtctattcg atgttgaccg
    57781 acgttttttc tatgccttca gatttggttt taagcgatat ctgtttagat gacattttgc
    57841 aaatggctta caacaagagt gcttatgaag gatggaaaaa ctatgcaata aaccaatccc
    57901 agaaaaacta aagaaaggag gtaaaaaatg gctaaaaaga gaacagaagc agaagtaact
    57961 ttcatagcta acgatgacgg attgaaatct acgttaaaag aaatcagtgc tgaattaact
    58021 aaaaatagag cagaattaaa actagaacaa gctcaattac aacagactgg ttctgaatca
    58081 gacaagttag gaagtaaatt atcttcttta gaaaagcagt atgaattaca aagtcaaaaa
    58141 gttgaagtaa ctagccaacg tttagccaat gcgaaaaaat attatggaga aaattccacc
    58201 gaagttcaga aacttgaaag agaactgatt aatcaacaaa cagcgcaaca acgtttgtca
    58261 aacgaaattg ataaaacgag taatgcacta gctcaagcaa aaggcgaaat acagacgtac
    58321 gagtctacaa tgcaacagtt ggatagcgaa caaaaaaatg ttcaagctag tgcttctctg
    58381 attgaatccg aatacaaaaa atggcaagca actgctggtc aatcagcttc tgaagccgag
    58441 aaattagcga aagcccaaga atatgtttct caacaatctg aaaatgcgga gaaaacgata
    58501 gatatcctaa gacgacagtt agaagctaca cagtctgaat ttggcgctac atccacagaa
    58561 gcaatgcaga tggaagcgaa gcttaatgat gctgaacgtg aatttgaaga gttaggacaa
    58621 gctgctaaaa atgtagatac aactaacttg gacgatatcg gaagcaaaat agatatgaat
    58681 aatttaatgg aagcttctga cgttttaagc gacattggcg ataagcttac agaattaggg
    58741 aaacaagcag tggactctgc taacagtgta ggtagttccc agagtaagat acaagctaat
    58801 tttggtttgt ctaaacaaga ggctgaagaa ttaacgaatg tagccagaga catttattat
    58861 aaaggttttg gagaatcgtt agatcagtcc acagatgcat tgattttggt aaagcgtaat
    58921 ttaggagatt taaataatca agatttacaa aatatcacgg aacaagctat ggtcctagaa
    58981 aacaccatgg gcgctgatat ggatgaaacg ttacgtggtg taaatggctt aatggtcaat
    59041 ttcggcttga gtgctcaaga tgcaatggat ttaatggttt cgggtactca aaacggttta
    59101 gataaaacgc acgaattagg cgacaatatg gcagaatata gccaattatg gagtcaaatg
    59161 ggatattcag ctgatgaaac gttcggaatg cttcaaaatg gtttagatgc gggtgcttat
    59221 aaccttgata aagtcaatga cttagttaag gaaatgggaa tatcgttaac agatggtcga
    59281 tttgagcaaa acatggatat gtttagtgaa agtactagaa aagcttttga agagtggaaa
    59341 aatggcggag gaacacaaaa agacgttatt aattccatga ttcaagattt tagcaatatg
    59401 gatggtcaat acgaccaatt aaataaagct tcgacaattt ggtctgcgct tggcgaagat
    59461 aatgcgatga aagttgtcca atctttaact gatgttaacc atacatttga tgatgttagt
    59521 ggatctgcac aaaaaatgaa tgaagattct actactccgt tgcaagagtt gaacgggaaa
    59581 atagctgaat taaaggattc attagctcct ataggcaaca caatcataga tgcactcgaa
    59641 ccagtaattg attttctagg aaagatggct gatgcgttta ataatcttcc acaaccagta
    59701 caggatttca ttgttgctat aggtggtctt acagcagcat ttggcatact gttaccggca
    59761 atactagccg tgtcatattt atttggtccg atgatgctta taattggagg aattatagct
    59821 gttatagcag gcgttattgt ggcaattaag aactggggtg caattactga ctggtttagt
    59881 ggtttatgga aaaaatttac tgattggttg ggtgatactt gggaaagtat aaaagacgga
    59941 gcctcatcag tttgggatgg ggttaaagaa acctggtctg gatttgtaga ttgggttcaa
    60001 gatatttggc aaggagtttc tgattggttt ggagagctat ggagcggatt agttgaagga
    60061 gcttccaaca tctggcaagg agtccaagaa acttggcaaa cattcgttga ttgggtttca
    60121 aatatttgga acggagtcaa agaagtatgg tcgattattt gggcagacat tgtaggaatt
    60181 gttcaaatac catggacatt aataacgtca ttgattcaag ctggtattaa tattatcgtg
    60241 ggtatttttg atgtagctgg acagttattg ggcgcagctt ggcaagctgt ttggacacct
    60301 atttctgatt tccttaaaaa tacttgggat actatgacac aatggataag tatcgcttgg
    60361 aatgggattg taactacatt ccatactata tttgatccag tagtggcatg gtggaatggt
    60421 atatggacag ctattagtac tacggcttca aatatttgga attcaattag tgcaacagct
    60481 tctagtattt ggaacagtat caagaataca atcactagct tggtacaagc agctgctaca
    60541 gtaattcaaa atatttggtc aactgtatct agttggttag gtggaatttg gaattcaatc
    60601 agctctacag catcaaatat ctggaatagt gtgactagta gtataagcaa tgctataaac
    60661 gcagctaaaa gtgccattca aagtgtttgg aatagtatat cttcgtggat tagcggaatt
    60721 tggaacggta tcaaaaatac tgctttgaat ctttggaatg gaattacaag cactattagc
    60781 tctaaagtaa acgatggaaa aaatgcaatt tcaagcggtt ggtccaatct aacaggtatt
    60841 gtttccgaca tattcaataa tgttaaaagt acaattgcta acatatggga aggcaccaaa
    60901 aagactgtta gcgctccaat tgattggatt agagacaaaa tcagtggcat ttttgataat
    60961 ttgaatattt ctataccaca tattccgtta ccggaattta tcatggaagg cagctttaac
    61021 ccgctaaaag gtcaaatccc ccatttgcgt gtaaaatggc atgctaaagg aggtatcttt
    61081 actaaaccaa ctttactagg tggaatgaac ggtgtcggtg aagcaggacc tgaagcagtt
    61141 ttacctttga aaagatctgt tttgcaagaa attggtgatc gtatcttgag tagcacatca
    61201 gtttcatcta gggcacaaac gattcaacct gtgaataact acgaattcaa tttcacaatt
    61261 gatggtaacg cagatgaggt tactatgaag caaacaactc aacaaatcat tgatagcatt
    61321 acaaaaattc aaaatgataa tgcttcggca tggcgttaaa caggagagta tttctcctgt
    61381 ttttttagta ttaaaaagga tgtgaaaaaa tgactgattg tatacattct ataatcgatg
    61441 gatttcctga ttatttgcat aaattggctt tagctgaaag accaaccata ccttctccaa
    61501 aaagacagag agttgaaact tctgttttag gtaggttagg tggcttagta caagattact
    61561 cgtttgaaga tatgtcgttt acattgcact ataactattt agaggatgtg gaagaccatc
    61621 aagcgttcaa gcaatcgttt tatatcatgc gtcattggtt aaactatgca aagaaattag
    61681 aattctctga cgatcccaac gtctattacg ttatccagac tatcgatatt ggggatgcag
    61741 aaaacgatat tgttgaatgg ggagagttcg atgtaaatat tactgcgaaa ccattcgcaa
    61801 gagttcaaga agatgtacct ataaccgtag ataaaccaca gtcatttaac ttgctgaata
    61861 atagtttaga agaaagtttt ccaaagatta tcatcactcc ttcagctact tcatgccagt
    61921 tcatcttaaa tgattatgtg tttagtttcg aaggcttagt agcaggaact gatgtagtca
    61981 ttgatagtga tttgatgctt tgctacgaag agcaatcgga cggagatatt ttagatcggt
    62041 ccaacaaaat gaagaccatg caatatccga cattgcaagt ggatatcaat cattttaatt
    62101 gcactggttt gagcaaaata caaatttatc gtaacgggtt aaggtaggtg aaatagatga
    62161 tcgataattt aataactatt tacgataaaa atgacgcgaa taatttagct gaacatttat
    62221 atgatacgca aggtttaggc gctttgtcag actggttaac agctactgtt agcaataaac
    62281 taaacggagc cgagatattt cagggtactt attcaataaa cggaactaat gcagatttga
    62341 ttgtagacgg acgtattatt cagtgttatg tagatgaaaa tcgagcaaaa cagcgtctac
    62401 ggatttatta tgcaaaaact tctgtaatag gcaatacgat agaagtaaaa gctgaaccta
    62461 ttttcaatga tataagaaaa tcggtgttga ataaatatga cagcggaaca gaaaagatca
    62521 ctgctactca ggcatggcaa aacgcaaaag ttttagcgaa accagctatc ccttcgcagt
    62581 tttctttctc gtcattagta gatacgcttg ctaatgtgaa gatagaaaag gcgaattttt
    62641 tagaattctt tggtggaaaa gagggatcta ttctagatcg atttcatggt gagtttctaa
    62701 aagataataa cacattacgt catgaaaaaa gtctaggtac ggatcataaa atcaaagcga
    62761 tttatactaa aaacttaact ggtcttgact tagagattga tgctcaaagt gttttagttg
    62821 gagtttatcc attcattagc agctcttcag aaggagaaga cgagatcact ctaccagaag
    62881 aagttatttt cacggattac gtggatgatt atcctgctgg atatgtttct tttgttgatt
    62941 ttaaagacaa agcgactgat gtagccacat taagggaagc tgctaaagac tggttgaaaa
    63001 caaacataga taaacaaaaa ccacaagtga gtggttcgat tgaattagta ccattgaggc
    63061 atcaaagagg ctatgaaaaa tttgttgatc tagaaaaagt ttcgatgggt gacggagtag
    63121 atgtgtatca tccacagtta aaagtgaata tgtcagcgag aattgtggaa tatacgttta
    63181 atgttctaac caattcatac gataaattag ttgtaggaaa cgtcaaaaca aacttcttag
    63241 aaaacacaga gaataatgtc agcaatttga ttaatgatgc cattgatcaa ttgaaaaacg
    63301 gtggcgaaat cagtgattta ctcaatgata ttgtagatca tcaaactgat atgattactg
    63361 gtcaaaatgg tggttatgtt ttattagatc ctaaagaagc gcctagtcgt attttgatta
    63421 tggacacacc agataagaat accgcaagga atgttttaca aatcaacaat gctggtattg
    63481 gtttttctaa aactggcatt aatggaacat atgaaacggc atggacgtta gatggcggat
    63541 tcaatgcctc gtttattacg gctggtgaaa tagtaggaat tactattaga ggtactacat
    63601 taattagtga tggtgctgat tatagaacaa gtattgctaa tggcaaaatg acttggtact
    63661 caaaaaaagt taacaaagat attatggagc tagaagcacg tgattatgta agtgctgatg
    63721 ccggtattgt atcatacacc atgaaaactg gtggtggttt catgattaga aatccacagg
    63781 gtaacttggt ttttagtacg tgggataatg gtaataacag accgtttcta tcttttggtg
    63841 cgcccaattt caggtatagc aatgctagtt atgtaacttc tggcgacggt agttctttaa
    63901 gcattaatgg tagtgcgggt aactcatggg aatttaaggt agctggtagg actatgaaat
    63961 ttactagtga tggtatgcta acgttaccag gttgtttttt ttgttcatgg gaagatggga
    64021 aacttgctag gtttgaacaa tcaacggtac aagtatataa agattttact gttagaggta
    64081 ctaaaaactc aactgtacca acagaacatt atggacaacg actattgaac gcttatgaaa
    64141 ctccagaata ttatttcgct gattatgggg aagccgttac aggtgacaat ggtaaagttc
    64201 gtgttgatat tgaccccatg tttgctgaaa cagtaaatct aagtcggtat atgacacatg
    64261 tgacacctac agaactagtt ttgtgtgctg ttactcatga agatattgac catttcatca
    64321 ttgaaactag taagccaaac gtattagtta gatggaattt agtggcacac cgtctagggt
    64381 atgaagatat tagattaaaa gaggatacag catatgatag cacagtgctt gaccaaaaac
    64441 gtttttaaaa cgaagacaag gaggtatata aatggctagc agtttatata atttggcttt
    64501 agatttcagc aaagaattaa actacaccaa agctattatg gctcgtcaag gtgataaagg
    64561 gattacggtg acggttaaac cgtttctaaa tggcttgcag atggatacga gtggcggaac
    64621 atttacttta aaaggaacaa caccatctaa ccgttacgta gataatgttg caactagtgt
    64681 aactagtgaa gaagtcacgt tttctcttga tggcacattt atgagtgaag caggatatta
    64741 taaacactgc tacgtagaat atagaaaaga caatcaaatt ttaacaacgc aagatatcat
    64801 ttttttctca ctaggagtgt ctgacatttc gcaaggccaa gccgatgaat atgtttcgca
    64861 attagaagag ttgattcgaa agtacaacga aacttttgat gcttttatgg ctgaaatcaa
    64921 aggtagagtg gatagcttaa atcaacagat tactgattta actggtcaag ctaaaacgct
    64981 acaagacaag ttagatgctc tgaaagaaga aatttctaag ttaggtaact tacaagtgat
    65041 gtacagtaac agcatcgact tcggggacta tgattattcg gagaacccga atttaatgcc
    65101 atatattaca gaaccttggg ttggaccttt gttaggtaat ggacatacag ttaaagatag
    65161 tgttaaaagg gttataactc atactaaaac tagaacagct aattccggcg acatattatc
    65221 gcttggctta ggtattccgt gtacagcgga agctaataat aggtatctta taaccacttt
    65281 acgaccatct acgacataca cattaagcgt tactatgagt gtcggttcag attggactgg
    65341 agagaccaat actatagggg ttaggcttag atatttaaat gaacaaggtg gtatagaact
    65401 gcccattaat gcattaatac cagcaaatgt agaacgcgat aaaatggtca ctcatacatt
    65461 tactggtata acaaaagata atgtaactag cataacaaac tgttatgttg aaatattctc
    65521 acttaatagt gaatataaag gaacggttag tgtcagctat gacgttaagt taaaagcaca
    65581 ctaccctaac ttactagatg gcccttactg gttaggtaaa gttcctttag gcgagaatat
    65641 tgctgaccct acagttgtct ttccacacaa aactagtgaa tatatggttt atggtagacg
    65701 caatacagaa aactatatcg ctgaccaaac atataccata tcaatgaaag caactaaact
    65761 aacagttcaa tcgtttgccg tgtatattgc tgctggccgc gttaaagtag gagacatgaa
    65821 gcctactgag gggttagcta atacatggga gttaactttt actgtaacta agcaacatat
    65881 agatagtggg gtaactaatt atctggaaat ataccaatac ccgtcagcta caaaaggagc
    65941 tgttcaaatt gagtggctca aactagaaaa aggcaatact cgaaccccga atattagtga
    66001 gtataaatat cgtggtactg gtatgcgtga ttcaaacaat ccaaaagatt atgtttggga
    66061 tctagcacca gaatatgtcg aagataattt ggccacagat attaaaattt ctgaaattac
    66121 tggtaaagca aacaattata ccgatgggaa agtatcggag attaattcgc agttgactgc
    66181 ttcaattaat gaagtagaca ccacagctaa ggatgctcaa acaaaagcga atgctaatgc
    66241 gactgctata gatgaattag acaataagat cgatgaacgc attaatgata cagctactac
    66301 cacattaaca gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac
    66361 agtttctata tattttgtgg ctttaaacgg aaaaagcagt ggtggaaatg attcaacgat
    66421 actaacaatt ccagaaggct atcggccacc aattagtttt gagcaactgg ttggctcgat
    66481 agaccgttct actttgaaca gtgctcagtt atctattggt gcagatggag ccattaaatg
    66541 gcgaagaaac tcaagttatg gatcggatta tacctttgca attacttaca cgatttagaa
    66601 aagcgtgaat cgatatgaag gcagcatata gaccaattga accttacgga ttcgagcaaa
    66661 tcattgtgaa tgatgaagaa catttaccgg aagaatgcac agaagtcgaa ccaccgattc
    66721 caaattggaa accgaaattc aattactggg agggaaataa atgaaaaaca tttggaaata
    66781 tggacgtact ggcggagagt acgcaggaaa agtattggac gacatgcttg tatccgttcc
    66841 ttacacagat cagccaccgc ttgaaggaat tcgtgctgat ggcgaaccgt taacaatcgc
    66901 tgatcaaatg tttgatccta aattgaatca atggattatt ttagcgaacg cactagatca
    66961 caacgattta aacaatctca aagcaatgta tgagtcgtta gaaaatgaga acggcgattt
    67021 aaaacagatc aatgccaaac tcatgctaag cgatgtagca attaaacagg aaaatactgc
    67081 attgaaagaa aaagcggata gtttagcaca aatcaattca aaaatgatgc ttgcttcgtt
    67141 acaaaatagc aaagacattt cagaaattaa agagcaacta aatccagctt caaagggagg
    67201 tgagtagtat gtttagtttt agcgatgtga aaatgatgta tgattggggc tgtttcacta
    67261 acgaacaagt aatggttttc gttccgttgt gcattactga agaaaaagca gataaaatca
    67321 ttagcaaaga agagagcgca tcttaattga tgtgcttttt attttgattc aaggagttgt
    67381 cacatgatta atttagggga atggggagcg atagcaggat caataaccgc tatcgtttct
    67441 ttgattttat tagtaataaa accaattact gcatctttct cgaagattac tgagactctt
    67501 tcaaaagtaa gtcacaattt agatttgctg actaaagatt tagaatcgag caaatcagat
    67561 cgattgatga ttcatgaaga actaaagaaa cacgatgaaa gattagatac acatgcagaa
    67621 aaattggtag aacacacgca acaaattaaa actttattta gggagagaag aaaatgaata
    67681 ataaaacgtt cgaagtacta aaatggttcg cactggtaat tattcccgca ctagctactt
    67741 tcgtggggtt agttggtaaa gcgctcaatt ggcagtacac agatatctgt gttgtcatca
    67801 ttactggttt tggcgcgttt ttagggagtg tgttgggtgt atcaaatcga acctacaaaa
    67861 tgttctcggc tgaaagcgaa gaaggaggaa acaaatgaaa aagaaaatta ctattactgc
    67921 gatgagcctg ttaacggctc tttttttatt acccattaat acgtttgctt atactattaa
    67981 tgacgagtat aatttagcgc cgaatcaagg agactccaga ttagcaattc ctaacaaaat
    68041 tattttgcac gaaactggaa tagatgcacc agcaagaaac gtagccgcca acatgaaaaa
    68101 taattataac ggaagcaatt cttatactac agatgttatt ggtgacggtg ggattgttta
    68161 ccgtgtgggt gagcaaggat atgtttcgtg gggagctggt aacgctaatc cttatgcgcc
    68221 tgtacagatt gaattacagc gcacatatga taaagcattg tttgaaaaaa actatcgagc
    68281 ttatattgaa tatacaagag atagtgcaaa aaaatatgga attccattga ctcttgatca
    68341 aggaacttct ttatttacaa aaggaatcat ttctcatttg tgggtgacaa attatgtttg
    68401 ggggaaccac acagatccat atggttactt atcgcaaatg ggagttagca aagaaaagct
    68461 tgcttatgat ttagctcatg gatttaccga tgaaaatcca acaacttctg aaaacaagcc
    68521 tgtcattgat ccaacacgag ctggtgcagc taatcctacg ctgacagatg gaacaaatca
    68581 cgcccacatt gatcagtttg gggaaatcga aaacgcaaac ttgcatgtgg ctggatggca
    68641 cattgctaac tataaatacg agtatatttt cattatggac tacaatactg ggaaagaatt
    68701 agctcgagta agagctgatg gaatttatag accagatgta aaccaagctt ataatacttc
    68761 tggaaatgtt ggttatcatg tatctttcaa tatgcgtaat tttcctagta agaaagtcta
    68821 tgtaatgatg cgggcaacga atgatccaga gggaaacact aaaggcggtg cgcaagattt
    68881 ccatgacaaa cgttggtatt taaatattcc taaacgataa aaatagctcc tcgttgagga
    68941 gcagtacata actatattga caactataaa aattattcga taaaatagtg atgttatcgc
    69001 atatcttcac tatcacccat aaatagtcac actccaagct atgcgataac aggtttgttg
    69061 ccacacattc tactggttga ttgtttatgg ctttatgtgg caacaaccag tacccttagc
    69121 tcagttggtc agagcagacg gctcataacc gtccggtcgt aggttcgagt cctacagggt
    69181 acattaacgt agccatttga atcgttctgt gttagaattt ttttgaagag tattatacaa
    69241 gctaaagctt ttcttcattg ccactcaaat gagtggcttt tttatgtatc cttttatgga
    69301 ttaatgaaag gatgtttcac atagttatac ttctgtatat ttgaaaagtt ttactttgat
    69361 ttttaaatag aaagacattt gggttaaatt gtgagataat aataaagaag agtttaaagc
    69421 gcaccccaaa ccacttcccc ataagtgtgt tacgctttaa actcttttat atttgaagcc
    69481 attaaaaagc ataccatatt tttgaaaaaa agtgagaaaa aaggcttaca attggagtgg
    69541 tagttaatta gtgacttatt tttgatttta tagcactgat actataaaat atagatatca
    69601 tcatattaca caatcttaat actaacttaa aaaatatctc ctttcacaag tatggtgata
    69661 aaattcgttc cgggctacct ttttaggtag cctactttaa tctttatacc tttctggatc
    69721 aacgaaagta tactttatat agtcataacg ccgatgatcg ctacgtgcgt ccggcacgtc
    69781 agtc
//
LOCUS       DAZKNV010000009        59709 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000009 DAZKNV010000000
VERSION     DAZKNV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.009"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..815
                     /locus_tag="ACG8M1_000659"
     CDS             <1..815
                     /locus_tag="ACG8M1_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFQ0421398.1"
                     /translation="LLSGCSKWIDRGESITAVGSSALQPLVETVAETYQTENPGKFIN
                     VQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRVAVVGITPIVNKDIGV
                     KDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRSTFEKWVLDGETAVQAQ
                     EQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTDENVTTNKWTIWAYEH
                     MYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVERDWQGNIVKE"
     gene            930..1850
                     /gene="pstC"
                     /locus_tag="ACG8M1_000660"
     CDS             930..1850
                     /gene="pstC"
                     /locus_tag="ACG8M1_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFQ0421399.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            1850..2734
                     /gene="pstA"
                     /locus_tag="ACG8M1_000661"
     CDS             1850..2734
                     /gene="pstA"
                     /locus_tag="ACG8M1_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFQ0421400.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2749..3555
                     /gene="pstB"
                     /locus_tag="ACG8M1_000662"
     CDS             2749..3555
                     /gene="pstB"
                     /locus_tag="ACG8M1_000662"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFQ0421401.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3571..4329
                     /gene="pstB"
                     /locus_tag="ACG8M1_000663"
     CDS             3571..4329
                     /gene="pstB"
                     /locus_tag="ACG8M1_000663"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFQ0421402.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4342..5019
                     /gene="phoU"
                     /locus_tag="ACG8M1_000664"
     CDS             4342..5019
                     /gene="phoU"
                     /locus_tag="ACG8M1_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFQ0421403.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5596..6288
                     /locus_tag="ACG8M1_000665"
     CDS             5596..6288
                     /locus_tag="ACG8M1_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFQ0421404.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            6285..7052
                     /locus_tag="ACG8M1_000666"
     CDS             6285..7052
                     /locus_tag="ACG8M1_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFQ0421405.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7152..8720
                     /gene="liaX"
                     /locus_tag="ACG8M1_000667"
     CDS             7152..8720
                     /gene="liaX"
                     /locus_tag="ACG8M1_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFQ0421406.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            9017..9337
                     /locus_tag="ACG8M1_000668"
     CDS             9017..9337
                     /locus_tag="ACG8M1_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFQ0421407.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9337..9687
                     /locus_tag="ACG8M1_000669"
     CDS             9337..9687
                     /locus_tag="ACG8M1_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFQ0421408.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            9854..10792
                     /gene="hprK"
                     /locus_tag="ACG8M1_000670"
     CDS             9854..10792
                     /gene="hprK"
                     /locus_tag="ACG8M1_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFQ0421409.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10807..11637
                     /gene="lgt"
                     /locus_tag="ACG8M1_000671"
     CDS             10807..11637
                     /gene="lgt"
                     /locus_tag="ACG8M1_000671"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFQ0421410.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11681..12706
                     /locus_tag="ACG8M1_000672"
     CDS             11681..12706
                     /locus_tag="ACG8M1_000672"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFQ0421411.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12721..13659
                     /gene="galU"
                     /locus_tag="ACG8M1_000673"
     CDS             12721..13659
                     /gene="galU"
                     /locus_tag="ACG8M1_000673"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFQ0421412.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13784..14224
                     /locus_tag="ACG8M1_000674"
     CDS             13784..14224
                     /locus_tag="ACG8M1_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFQ0421413.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14227..14829
                     /locus_tag="ACG8M1_000675"
     CDS             14227..14829
                     /locus_tag="ACG8M1_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFQ0421414.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(14888..15994)
                     /locus_tag="ACG8M1_000676"
     CDS             complement(14888..15994)
                     /locus_tag="ACG8M1_000676"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFQ0421415.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16204..17205
                     /gene="ccpA"
                     /locus_tag="ACG8M1_000677"
     CDS             16204..17205
                     /gene="ccpA"
                     /locus_tag="ACG8M1_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFQ0421416.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17542..19887)
                     /locus_tag="ACG8M1_000678"
     CDS             complement(17542..19887)
                     /locus_tag="ACG8M1_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFQ0421417.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     RIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20166..21068
                     /locus_tag="ACG8M1_000679"
     CDS             20166..21068
                     /locus_tag="ACG8M1_000679"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFQ0421418.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            21281..23056
                     /locus_tag="ACG8M1_000680"
     CDS             21281..23056
                     /locus_tag="ACG8M1_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFQ0421419.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(23122..24708)
                     /locus_tag="ACG8M1_000681"
     CDS             complement(23122..24708)
                     /locus_tag="ACG8M1_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFQ0421420.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            24959..25183
                     /locus_tag="ACG8M1_000682"
     CDS             24959..25183
                     /locus_tag="ACG8M1_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFQ0421421.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            25325..27076
                     /locus_tag="ACG8M1_000683"
     CDS             25325..27076
                     /locus_tag="ACG8M1_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFQ0421422.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            27076..28860
                     /locus_tag="ACG8M1_000684"
     CDS             27076..28860
                     /locus_tag="ACG8M1_000684"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421423.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            29186..30037
                     /gene="licT"
                     /locus_tag="ACG8M1_000685"
     CDS             29186..30037
                     /gene="licT"
                     /locus_tag="ACG8M1_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFQ0421424.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            30130..32016
                     /locus_tag="ACG8M1_000686"
                     /pseudo
     CDS             30130..32016
                     /locus_tag="ACG8M1_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
     gene            complement(32056..32958)
                     /locus_tag="ACG8M1_000687"
     CDS             complement(32056..32958)
                     /locus_tag="ACG8M1_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0421425.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            33189..34592
                     /locus_tag="ACG8M1_000688"
     CDS             33189..34592
                     /locus_tag="ACG8M1_000688"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFQ0421426.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            34592..36025
                     /locus_tag="ACG8M1_000689"
     CDS             34592..36025
                     /locus_tag="ACG8M1_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFQ0421427.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            36170..37096
                     /gene="trxB"
                     /locus_tag="ACG8M1_000690"
     CDS             36170..37096
                     /gene="trxB"
                     /locus_tag="ACG8M1_000690"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFQ0421428.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            37310..39037
                     /locus_tag="ACG8M1_000691"
     CDS             37310..39037
                     /locus_tag="ACG8M1_000691"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFQ0421429.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            39052..39402
                     /locus_tag="ACG8M1_000692"
     CDS             39052..39402
                     /locus_tag="ACG8M1_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFQ0421430.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(39494..40354)
                     /locus_tag="ACG8M1_000693"
     CDS             complement(39494..40354)
                     /locus_tag="ACG8M1_000693"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFQ0421431.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            40446..40874
                     /locus_tag="ACG8M1_000694"
     CDS             40446..40874
                     /locus_tag="ACG8M1_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0421432.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            41037..41213
                     /gene="rpsU"
                     /locus_tag="ACG8M1_000695"
     CDS             41037..41213
                     /gene="rpsU"
                     /locus_tag="ACG8M1_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFQ0421433.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            41240..41686
                     /locus_tag="ACG8M1_000696"
     CDS             41240..41686
                     /locus_tag="ACG8M1_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFQ0421434.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(41840..43219)
                     /gene="brnQ"
                     /locus_tag="ACG8M1_000697"
     CDS             complement(41840..43219)
                     /gene="brnQ"
                     /locus_tag="ACG8M1_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFQ0421435.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            43925..44896
                     /locus_tag="ACG8M1_000698"
     CDS             43925..44896
                     /locus_tag="ACG8M1_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFQ0421436.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            44920..47112
                     /locus_tag="ACG8M1_000699"
     CDS             44920..47112
                     /locus_tag="ACG8M1_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFQ0421437.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            47129..47605
                     /gene="ybeY"
                     /locus_tag="ACG8M1_000700"
     CDS             47129..47605
                     /gene="ybeY"
                     /locus_tag="ACG8M1_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFQ0421438.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            47589..47984
                     /locus_tag="ACG8M1_000701"
     CDS             47589..47984
                     /locus_tag="ACG8M1_000701"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0421439.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            47999..48898
                     /gene="era"
                     /locus_tag="ACG8M1_000702"
     CDS             47999..48898
                     /gene="era"
                     /locus_tag="ACG8M1_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFQ0421440.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFTQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            49041..49853
                     /gene="recO"
                     /locus_tag="ACG8M1_000703"
     CDS             49041..49853
                     /gene="recO"
                     /locus_tag="ACG8M1_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFQ0421441.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            50237..51154
                     /gene="glyQ"
                     /locus_tag="ACG8M1_000704"
     CDS             50237..51154
                     /gene="glyQ"
                     /locus_tag="ACG8M1_000704"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFQ0421442.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            51156..53231
                     /gene="glyS"
                     /locus_tag="ACG8M1_000705"
     CDS             51156..53231
                     /gene="glyS"
                     /locus_tag="ACG8M1_000705"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFQ0421443.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGKASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            53622..54401
                     /locus_tag="ACG8M1_000706"
     CDS             53622..54401
                     /locus_tag="ACG8M1_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421444.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTIVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIDQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            54447..55391
                     /locus_tag="ACG8M1_000707"
     CDS             54447..55391
                     /locus_tag="ACG8M1_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0421445.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            55407..56186
                     /locus_tag="ACG8M1_000708"
     CDS             55407..56186
                     /locus_tag="ACG8M1_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFQ0421446.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKEAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNGKTAPSRRSRSRV"
     gene            56198..56896
                     /locus_tag="ACG8M1_000709"
     CDS             56198..56896
                     /locus_tag="ACG8M1_000709"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFQ0421447.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLSNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQIFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLSKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            56924..57688
                     /locus_tag="ACG8M1_000710"
     CDS             56924..57688
                     /locus_tag="ACG8M1_000710"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFQ0421448.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFRKNPNYLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIGKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            57701..59518
                     /locus_tag="ACG8M1_000711"
     CDS             57701..59518
                     /locus_tag="ACG8M1_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFQ0421449.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            59530..>59709
                     /locus_tag="ACG8M1_000712"
     CDS             59530..>59709
                     /locus_tag="ACG8M1_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HFQ0421450.1"
                     /translation="MNILILSCGRRCELVNAFKTALNNNEMEGKIIGADCSELAPALY
                     MCDEKIVLPKVSESNY"
BASE COUNT        19562 a        10599 c        12669 g        16879 t
ORIGIN      
        1 ttcttttatc aggctgttca aagtggattg atcgaggaga atccattacg gctgttggct
       61 cttctgcttt acagccttta gtagaaacag ttgctgaaac ttaccagaca gaaaatcctg
      121 gaaaattcat caatgtacaa gggggcggaa gcggaactgg tttgtctcaa gtacagtcag
      181 gagcagtcga catcggaaac tctgatttgt ttgcggaaga aaaatcgggg atcgatgcct
      241 cagcattagt cgatcatcga gtagcagttg ttgggatcac tcctattgtg aacaaggata
      301 ttggcgtaaa agacatcagt atggaaaacc tgaaaaaact atttacaggc gagatcaaaa
      361 actggagtga agtcggtgga aaagatcagc cagtagttat attgaaccgc gcttcaggaa
      421 gcggaacccg tagcacgttt gaaaaatggg tattggacgg agaaacagct gttcaggcac
      481 aagaacaaga ttcaagcgga atggtgcgcc agatcgttgc cgacacaccc ggtgcaatca
      541 gctatgttgc tttttcttat gtttccgatg atgtagatac gttgaatgtt aacggtgtag
      601 aaccgacaga tgaaaatgtg acaacgaaca aatggacgat ttgggcatat gagcatatgt
      661 acacaagaga tcatccaaaa aaactgacaa aagaattttt agactatatc ttatctgatg
      721 aagtacaaga taacatcgtt ggagaactag gttatatccc tgtttctcat atgaaagtcg
      781 aacgtgattg gcaaggaaat atcgttaaag agtaatcttt acacaaaatt tacaaactta
      841 gctaaacttt tacatgttat taaaaccaaa ttgatgttca atttgtacac tgagtgagta
      901 tgttaaacct gattaagggg gagtcatctg tggaagatgt gaaaaaagta ttattaacaa
      961 aatcaaaacg ttcaaaaatg gaacagcgtg gaaaattcat cagtttttta tgtatcgcgc
     1021 tgatcgtgtt ggttgtatta tctatttttt attttgtagc tagtaaagga ttggccacct
     1081 tttttactga taagatcaat gtatttgatt ttctgtttgg tacagattgg aatccaagcc
     1141 aaatcggagc aaatgggaaa ccaatggtag gggcattgcc tatgatcaca ggttcgttta
     1201 ttgtgacctt tttatctgct atcgttgcca cgccatttgc cattggtgca gcagtattca
     1261 tgacggagat ctctcctaaa aacggaacga agatcttaca gccggtcatc gagctgcttg
     1321 taggtattcc ttctgtcgtt tatggtttta tcggtttatc agttatcgtg ccttttgtca
     1381 gaagtatttt tggcgggact gggtttggta tcttagctgg tacatttgtg ttgttcgtta
     1441 tgatcttgcc gactgtcaca acgatgactg ttgatgcatt aaaggcagtg ccacggcact
     1501 atcgggaagc ttcattagcg cttggtgcca caagatggca aacaatctac aaagtcgtgc
     1561 tacgagcagc cgtgcccggg attttaacag cagtcgtttt tggtatggct cgtgcgtttg
     1621 gtgaagcctt agctatccaa atggtcatcg gtaatgcagc attgatgcca acaggtctta
     1681 ctactcctgc ttctacattg acgtccatct taacaatggg aatcggaaat acaatcatgg
     1741 gaacagttga aaataatgtg ttatggtcat tagcgctgat cttgctattg atgtcattat
     1801 tctttaatat cgtgatccgt atgattggga agaaaggaga gctgaaataa tgaacgcaaa
     1861 acgctcagat aaaattgcta caggtgtttt atatatagtt tcggggatca tcgtattgat
     1921 tttagcagct ttactacttt atatcttagt tcggggaata ccgcacattt catggtcctt
     1981 cttgaccgaa ccttccaaag cctaccaaga aggcggtgga atcgggatcc agctatttaa
     2041 ctcgatttat ttgcttttga tcacgatgat catcagtttt cctatttctt taggtgcggg
     2101 tatctatctt tcagaatatg ctggaaaaaa ctggctaaca gatgtgattc gcacgtcgat
     2161 tgaaatcttg agctcgttgc cttctgtcgt tgtcggttta ttcggtttct tggttttcgt
     2221 tattcaattc cagtatggtt tctcgattat ttctggtgca ttggctttga ctgtattcaa
     2281 cttgcctctt ttgactagaa cagttgagga gtctttacaa gcggtccatt acacacaacg
     2341 agaagcagga ttggccttag gtttgtcacg ctgggaaaca gtgataaaag tggtggttcc
     2401 agaagcgaca ccagggattt tgactggtgt gatcctaagt tctggaagaa tttttggtga
     2461 agcagctgca ttgatctata cggctggaca aagtgcacct gcgttagatt ttacgaactg
     2521 gaatccatta agtgtttcaa gcccgatcag cattttccgt caagctgaaa cattagctgt
     2581 ccatatttgg aagatcaata cagaaggcac gatgcctgat ggtgtttctg tttcggctgg
     2641 cgcttctgcc gtgttgatta ttgctgtttt actgttcaac ttcggcgctc gtgcgattgg
     2701 caaacgatta taccgaaaaa tgacttcagc ctaaggagaa gaagcaaaat gaaaaaatat
     2761 aactggaatg aaacaaatgt catcaccatg ccaaaagaga aagaagtagc actatatacg
     2821 gatgatctac atgtctggta tggcgacaat gaagcaatca aaggagtgga tctggaattt
     2881 gaaaaaaata agatcactgc actgattggt ccttccggct gcggaaaatc tacgtatctt
     2941 cgttcgttga atcgaatgaa tgatgggatc gctaatacga aaatcactgg gaaaatcatg
     3001 tatcaaggcg tagatattaa tgcgcctcaa gtggatgttt atgagatgcg caaacggatt
     3061 ggcatggttt ttcaacgtcc taatccgttc agcaagtcga tttatgacaa tattacattt
     3121 gctttgaaac agcacggcga aaaaaacaaa aagaaattag atgaaatcgt tgaaacaagc
     3181 ttgaaacaag ctgccttgtg ggaccaagta aaagacagct tggacaaaag tgccttggct
     3241 ttatctggcg ggcaacagca acgtttatgt attgctcgtg cgatcgcgat gaaacctgat
     3301 atcttgctgc tagacgagcc ggcaagtgct ttggacccta tttcgacagg aacggttgaa
     3361 gaaacacttg taaacttgaa agaagactat acgatcatca tcgtgacgca taacatgcaa
     3421 caagcagctc gtatcagcga ctatactgcc tttttctatt taggaaaagt aatggaatat
     3481 gacaaaacta acaagatatt taccagacca aaaattcagg caaccgaaga ttatgtgtcc
     3541 ggtcattttg gttaagacgg aggcctcaac atgacaaaag agattatttc atctaaagat
     3601 cttcatctgt attatggaaa gaaagaagca ctaaaaggga tcgatctaag cttcaatcaa
     3661 ggggaaatca ctgcgatgat cggtccttct ggttgcggaa aatccactta tctgcgttct
     3721 ttgaaccgga tgaatgacct gattccgaat gtaacgatca ccggaagtgt tttatataaa
     3781 gacaaagaca tctatggtcc aaaaacagat gttgttgaac taagaaaaga aatcggcatg
     3841 gtattccagc agccaaaccc atttcctttt tctatctatg aaaatgtcat ctatggattg
     3901 aaattaaaag gggaaaaaga taaaaaagtc cttgatcaag tagttgaaga aagcctgaag
     3961 gcagcgtctg tttgggatga tgtgaaagac aaattgcata aaagtgcttt atctttatcc
     4021 ggtgggcagc agcagcgtgt atgtatcgca cgtgttttgg cagttaatcc ggaaatcatc
     4081 ttattggatg aaccaacaag tgcgcttgat cctgtttcta ctgggaaaat cgaaagtatg
     4141 ctgttagaat taagagagcg gtatacgatg atcatcgtga cccataatat gtctcaagct
     4201 tcacgtattt cagataagac ggcattcttt ttagatggtc acttgatcga atacaatgat
     4261 acgaagaaga tattcatgaa tccagaaaaa caagagacag aagattatat ttcaggtcga
     4321 tttggataag gaggaaacgg aatgctacgt acacaatttg aagaagaatt gctgaatctc
     4381 cataatcagt tctacgaaat ggggatgatg gtgagcagcg ccgtgcacaa gtcagttcgt
     4441 gcatacatca aacacgataa aatcttagcc caagaagtta tcgaaaacga tataaatatc
     4501 aataacatgg aaacacgctt ggagaagaaa agttttgaaa tgatcgcatt gcaacagcca
     4561 gttacaactg atttgcgtat gatcattacg gtcatgaaag ctagctcgga tttagaacgt
     4621 atggccgatc atgcggtgtc tgttgctaaa tccacgattc gcgtaaaagg gcagacgaga
     4681 ataccggaaa tcgaaaaaga gatctccgat atgtccgatt atgtgaaaaa aatggtggac
     4741 aacgtcctag ttgcttatgt caaaacagac gaaaaagacg cacgtacgat cgccaatatg
     4801 gatcaaagag tcaatgacta tttcaatcga atctataatg caacaatcaa aaatatgcag
     4861 gaaaatcctg agacagtcat cagtggaaca gactacttga atgttgccag ttatctagaa
     4921 cggatcggag actatgtgac aaacatctgt gaatggatcg tctacttggc tacagggaaa
     4981 atcactgagt taaatacgaa ccacaatgag attttctaaa ctgaagctgt gattatgccg
     5041 tttgtttagg aaaagaggtt gtgaaatcag cggttgtgaa aaagctgttc tgcatcaagt
     5101 aataagaaca gtcaaacaaa aaatagctcc tcatattttt cgtttggctg gacttattac
     5161 cgcagatgca agcttttgaa caccgtttat tcgggaaagg gtttgtgaca aaacatgtca
     5221 caaacccttt tcatcatttc atagaaagga taaagaatgc aaaaaaaaat tagcatcatc
     5281 actatatttt ttatttgtgt gcttacttca tgggttattc agcatcaagc cgctttatat
     5341 gaagtacctg tcatcgagat agaaaaagta cgaataaaag aggatcatca attgattaca
     5401 ggaaaactga tgaacacgga tcaaaaagga gaatcgattt atttatcggt tccttatcaa
     5461 aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa tgtatctagt ccaaatgcat
     5521 ggagatgaat ggcagctagt agcaaaaaaa aatgatggct ggcttttctt cttcacaagt
     5581 atcttcattg gcgccatgtt gcttattggt ggaaaacagg gtctatttgc tttaggaagt
     5641 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
     5701 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
     5761 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
     5821 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
     5881 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
     5941 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
     6001 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
     6061 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
     6121 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
     6181 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
     6241 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     6301 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     6361 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     6421 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     6481 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     6541 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcaatc caaggtttta
     6601 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     6661 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gcgagtgtag
     6721 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     6781 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     6841 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     6901 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     6961 ccacattgtc cgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     7021 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     7081 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     7141 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     7201 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     7261 tcaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     7321 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     7381 gagaaagaca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     7441 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     7501 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     7561 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     7621 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     7681 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     7741 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     7801 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     7861 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     7921 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     7981 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     8041 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     8101 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     8161 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     8221 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     8281 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     8341 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     8401 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     8461 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     8521 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     8581 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     8641 gtgtttcaga tggtgaaatc gcgcaagtgc aactttcaac gacaacagga agtatctatt
     8701 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     8761 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgatagtcta
     8821 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     8881 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     8941 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     9001 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tctaataaaa atgttgtttt
     9061 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     9121 gctttatgta ttcctgagct tagttgcttt tggaagtcca attattttat acattttatt
     9181 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     9241 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     9301 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     9361 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     9421 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     9481 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     9541 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     9601 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     9661 gtcagcgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     9721 tttatttaga atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt
     9781 ttaattggta gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa
     9841 tgaggtagca tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt
     9901 ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc
     9961 acgcccagga ctagagttga ctggttattt taattattat tcccataatc gtttacagct
    10021 atttggcagt aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat
    10081 catgagaaga ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccagc
    10141 tccagaagaa atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat
    10201 ctcaacttct cgtttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg
    10261 aacaagtgtc cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga
    10321 cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggcc atcgattgat
    10381 cgcagacgat cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc
    10441 taaaatcctg gaacatctga ttgaaatccg aggaatcggg atcattgatg taatgaatct
    10501 ttttggtgcg agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc
    10561 atgggcaaaa gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc
    10621 ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat
    10681 cattgaagta gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac
    10741 atttgaagaa agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt
    10801 gacaatatgt tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac
    10861 tggtatgcat tgatcatcgt atcaggtatc attatcgcta tgtggcttag cagcagagag
    10921 gctgttcggg taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct
    10981 atctccatta ttggcgctcg cttatattat gttttatttg atcttcccca gtatatagct
    11041 gatccaatcc aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt
    11101 gcaggcgcga tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt
    11161 ttagatatcg ctgcaccaag tgtattatta gcacaggcaa tcggtcgttg gggaaatttc
    11221 atgaaccacg aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta
    11281 ccgcaattca tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt
    11341 tatgaatcac tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca
    11401 caccttttga aaaaaggcga agtcctttta tgttatctaa tgtggtatag tttcgggcgt
    11461 ttctttattg aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct
    11521 caattattat ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa
    11581 aaaggaaatt taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt
    11641 ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt
    11701 tttaggacca ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga
    11761 cgttcggatt tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa
    11821 tcaacgttat ttaccagatc attatctacc cgattccatc caagcattca ccaatatgga
    11881 agatgcagta aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc
    11941 tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa
    12001 aggattagaa cagggaacac ataaaaggat ctctgacatc ttgttagagg aaatcccagc
    12061 agaaaaaaga aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcaaa
    12121 acatgacatc actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca
    12181 agagctgttc atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga
    12241 gatgggggca gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg
    12301 gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt
    12361 aggtgtagca atgggtgcca acccgctgac ctttatcgga ttaagcggaa taggcgatct
    12421 agtcgttact tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca
    12481 agggcagccc ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac
    12541 tacccaagca gcgatggaac tagcccaaat gatggaaatc gaaatgccca tcactcaaac
    12601 aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt
    12661 acgtgatgga aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat
    12721 atgaaagtta aaaaagcagt tattccagca gcaggattag gaacaagatt tttaccagca
    12781 acaaaagcta tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc
    12841 gttgaagaag cgttgaaatc aggtatcgaa gacatcttga tcgttacagg aaaagctaaa
    12901 cgaccaatcg aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa
    12961 ggaaagaccg aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc
    13021 cgtcaatctc atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga
    13081 aatgaaccat ttgtcgttat gctaggcgat gatataatgg aagacgaagt accattgaca
    13141 cagcaattaa tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt
    13201 cctcatgatg aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg
    13261 ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta
    13321 gctattattg gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa
    13381 ccaggagccg gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa
    13441 cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt
    13501 atgaaaacaa gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag
    13561 tacatcctgt ctttaggtaa aacattagaa gcagaaggaa gcaagatcga tcataatcca
    13621 aaaggaataa cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc
    13681 agctgctaat tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa
    13741 atgctatcct tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat
    13801 tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt
    13861 gttgcaagtt tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac
    13921 gatcgaaatc gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttactggt
    13981 caaaagtaat gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt
    14041 cacagcagtt gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat
    14101 cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt
    14161 cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa
    14221 ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag tagtcggagg cacagccgca
    14281 gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct
    14341 gcccaagcgg atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa
    14401 tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt
    14461 gatctagcag gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa
    14521 tctgacgata tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa
    14581 aaaacggcag aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact
    14641 tcagaagata tcatgattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat
    14701 gaaggaatgt cagaagcaaa accagttgca gatgactcaa aagaaatgat gaaaatggca
    14761 aaagaagatg cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca
    14821 aatcactaaa atcacaaatt tatagaataa aaaggtggga gcggactagc tctcaccttt
    14881 tttactctta tttttctaaa acaagtaatt cttttggtgt agtcgtgaat ggcacacagc
    14941 catcgcttgt cacatataca cagtcttcga tacgtacccc tactttttca ggaatataga
    15001 ttcctggttc aagagagaag cacatccctt cttcgattac taagtcattt ccttctacaa
    15061 gggaagggaa ttcgtggacg gttgttccga tcccgtgacc taaacggtga ttgaaatatt
    15121 cgccgtagcc atagctgttg atcacgtttc gtgcgatttg atcaagttca cctgctgtca
    15181 cacctggacg gacggcttct tgtgcggcaa gctgtgcttc aagagtgatg ttgtagattt
    15241 tttcttggaa gtcggttggt ttttgataag caattgtacg agtagcatca ctgcaatagc
    15301 cattccaaac aacgccaaga tcgaataaca caagttcatt cggtgaaatc ttcgtatttc
    15361 ctggtgtacc atgagggctt gcagcatttg ctcctgcaag gactaatgtg tcgaaagaca
    15421 tttgtgaaac accttgtttt ttcaattggt attcaatttc tgcaatgatc gcttgttcag
    15481 tcacgccttc tttcactgct ttaaagccaa tctcaaatgc aacatcggcc catttaccag
    15541 cttcgatcag tttgtctttt tcctctagag ttttgatcag ttgtagacgt tggatgatgg
    15601 aagttagatc agtgtaagaa tccgttcccg tcaagatatc agagatagca tcgaagcgct
    15661 cgacagtcaa ggcgttcttt tcaatcccta cattgccagg ctgaccatag cgagcacgaa
    15721 gttcttttcc gatgatctcc caagggtttt cgctgtctaa atagccacgg acatcatacg
    15781 cccaactact gttttgagca tcttcaactt ccaaagcagg agtgaaaagg aaaggatctt
    15841 gttcaagagg gataaaaaga gctagtacac gctcatgagg atcactttcg tatccggaaa
    15901 agtaagcgat gtggccaggg tcgctgatat aagccaattc gacttggtgt tgtgccatcc
    15961 attgacgtag ttcattgatt tttacgttat tcatttggca acctactttc taaattaatt
    16021 ttgtattcaa taattgtacc actgatttat taaaagacca acgttctaaa aactgaaaaa
    16081 agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa ttcttgagat tatttgatat
    16141 tctattttag aaatgtaaga cgtattttca gaaaacatat aaaatatgaa taggagaaca
    16201 caaatggaaa agcaaacaat cactatctat gatgtagcga gagaggcaaa tgtttcgatg
    16261 gctactgttt cacgtgtcgt aaatggcaat ccaaacgtta aaccagcaac aagaaaaaaa
    16321 gtcttggaag ttatcgatcg cttggattat cgtccaaacg cagttgcgcg tggcttggca
    16381 agtaagaaaa caacaacagt tggtgtaatc atccctgatg tcagcaatat gttctttgct
    16441 tctttagcac gtggtatcga tgatgtggca acaatgtaca aatacaatat tatcttagca
    16501 aattcagatg gcaacgacca aaaagaagtc aatgtattga ataacttact ggctaagcaa
    16561 gtggacggcg tgatcttcat gggtcaccat atcacagacg aaatccgtgg agaattttca
    16621 cgttcaaaaa ctcctgttgt attagctggc tctattgatc cagatgaaca agtaggtagc
    16681 gtaaacattg attatgtatc cgcaacaaaa gatgcagtaa acaaattggc aaaaagcggc
    16741 aataaaaaaa tcgcttttgt cagtggtgcg ttgatcgatc ccatcaatgg acaaaatcgt
    16801 ctgaaaggct ataaagaagc attaagcgaa aataacctac catatagcga aggattgatc
    16861 tttgaagcac aatacaactt caaagatggt ctatctctag tcgatcggat ccataatagc
    16921 ggtgcaacag ctgtctatgt ttcagatgat gaattagcca tcggtatttt ggatggttta
    16981 ttagaccgtg gcgtgaaagt accggaagaa ttcgaaatca tcacaagtaa caattcacta
    17041 ctgacagaag tagctcgtcc tcgtttaaca agtatcacac aaccattata cgatttaggg
    17101 gcggtatcta tgcgcctatt gacgaaaatg atgaataaag aagaagtcga agaaaaaacg
    17161 attatcttgc cttatggaat cgaagaaaaa ggatctacaa aataataaaa ggacaaccat
    17221 tcagaggttg tgtgcctgcc gtttaactct gcgttacaag gagcaatttc aaaaaacagc
    17281 atctcatgtt tgatgaatat tgtgactcgt gattcggagt tggcaggaga acaccgttta
    17341 tttgggaaaa ggggttatga caaaattttg ttataatcct ttttttgtgt cttaaaaaag
    17401 agagaaagtg gttgaaatta catttatcgt atataaaaca atccgtgtat agatgctgca
    17461 ttttgttcac caccatcaaa aaaataaggg actgtgacaa tactattgtc acaatccctt
    17521 attactgtgt attctattaa atcaatcatc tttctcatct gattctttag ttgcttgatt
    17581 cgctcttgca taagctgaag cggtgttcca gtaatctgta tagttttcat cggtaccgcc
    17641 aacgccaaat ttaaaggcgc ttttcttcgg tccatttttc gcccatagcg attcaactgt
    17701 ttttcctggt gtttggatgg attttttatt gacagtaact tttccaggtg tttgaccagt
    17761 aaatccagat acttttttct tcatcacatc agatgataat tcgaatttct catcagtgcc
    17821 aaaaatgtca ggttttgctt ggtaagcttg attgatcaga ttggcaagat aattagccga
    17881 acgtatcctt gctttgctgt ccattccagt attgtcatcg tgccctgccc agctactgat
    17941 ggtaatagac ggagtagaga caattagcca tgaatctcgg tattcattgg tagaaccagt
    18001 ttttccgacc caatctgctt ttcctagatt tccgtttaag cttgagatgg catctttgaa
    18061 tggtgtagtg atttttgcat tgatcacact acgcatcatg tcattcatga tcgatgccgt
    18121 tgcttccgaa tagatccgga cagagttgct ttcgtgttta taaattacat ttcctgcgtt
    18181 atctgtgatg gaatcgatga tatagccttc ttcatagacg ccgccgtttg ctaaagcctg
    18241 aaatccgttg gtctgttgaa gcgtcgtgac atctactgta cctaaaggag cagattcaac
    18301 gccccaattg tcatttgccg ggtagttcat ctttgccaag tagtgctcgt aagcatattg
    18361 tttcgatcca ccggaattca acacatcttg atataagtga taagccggga tattgttgga
    18421 ccattctagt gactcacgga cggtttggaa ggtgttcgat ccttcgttag tagcattgac
    18481 gattttctcg ccagcatttt ctccttcttg ccaagttgtt gcataatctg atacacggga
    18541 ttctgatccg ataagcccca tgtcgattgc aggtccataa acaagaactg gtttgattga
    18601 tgagccagct tgacgttctg tatcgaaggc atggttattt tgattctgac tgtaattccg
    18661 tccgccaacg aatccgtaga tgcggccagt tctgttatcc atcaatacat ttccggtttc
    18721 tacttgactg ccagcaccat catctaacat gtatccataa ttttcaacgc cattttgcaa
    18781 tgcagcatag acatctttat cgattgtcga atggattgta tatcctttat tttggatcgt
    18841 ttgctgtgcc ttttgataat aagcgtcact gaccgatgaa tcagacatat cagcgttgtc
    18901 tttttcagcc aattgttgtg caatgattct tgttgcttca ttcatcacag tataatacaa
    18961 gaattctctg tcagtctgtt ctgcgatttg ttgtggtaga aagtcttttg taaggtcata
    19021 ggcttttgct tcttcgtatt gttctttcgt aatttggcct tcacgataca tactgaataa
    19081 aacaaaatct tttctggcaa ggccggcaga aagatcttct tttagcgcgc ctgtgttcgt
    19141 gtatggacta tacgtgatcg ggctttgggg taatccagcg atataagcag cttgcggcag
    19201 cgtcacatct tttgcatcta caccaaagat tctttttgca gcttcctgga ctccagcaat
    19261 gttttgtccc ttattattac gaccaaatgg tgagacattc aaatacgtag caatgatctc
    19321 atcttttgaa aagtattttt ctacttgtgc agaaagaatg atctcgtttg ctttacgttt
    19381 gaatgttgtt tcatctgtaa ggatctgctg tttgactaat tgctgtgtca aagttgatcc
    19441 accagaagag ccaataccag tagcttcaga tactaatgct cgtaaaacag ctttaggaac
    19501 gtaaccttgg tgtttatcga agtattcatc ctctgtgctg ataattgcag ttttcaataa
    19561 aggtgaaatc ttatcagatg aaatagtcgt gcgcatcaga tctgtctgga tttttgatat
    19621 ctctgtatta tctgcataaa caatctttga cgtttctgta atgtttccta gttctgtctg
    19681 cagtgctttt ttagtcggca attgtgtgtc ttcgacgaga taggcaaaat agccagcgcc
    19741 tattccaata cctagagctg cgaacatcaa aagaagaaca gtaataaaaa cagtcaatga
    19801 ttgaaaaact ctaaaaataa tcttaggaac aaaccatttt tctttttttc ttctattctg
    19861 tttttttcga gtatttttgc gtggcaaaag ggtcacctca actaatggtt ttatttcgct
    19921 aattatagca aataatagaa caaaaaaaca gacaaggctg tttttggcag gaatttcttt
    19981 tttaaaagag ttaaaacgtg agaaaatgat ctttattata aaagagttct taagcttttc
    20041 tttagagaaa atttcagtta ctatggagaa cagggcaaag aaaaatcaat cattttcttt
    20101 gtatatcatc ttaccaatat ataggaattg ttagtaacaa ttgcctttca aggaggaatc
    20161 catccatgtt attaggctca cacgtcagca tgagcggaaa gaaaatgctg ttaggagcag
    20221 cagaagaagc agccagttat ggatcttcga cttttatgat ctatacaggc gcccctcaaa
    20281 acactagaag aaaagccatc gaagagatga atattgatgc cggaaaagcg tacatggcag
    20341 aaaaaggtct aacaaatatc gtcgttcatg ccccttatat cattaatttg gggaatacga
    20401 tcaaaccaga aatgtttcct tttgccgtcc aatttctgag agaagagatt gttcgtgcgg
    20461 aagctttagg cgctactcaa attacacttc acccaggtgc tcatgtaggg gcaggaacag
    20521 aagccggaat tgctagaatt attgaaggct tgaatgaagt tttgacaaaa gaacagacgg
    20581 cacaaatcgc tttggagaca atggcaggta aaggtacgga aatcggtcga acatttgagg
    20641 aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt acttttgaca
    20701 cctgtcatac gaatgatgcc ggttataata ttaaagaaga cttttcaggt gtaatggaag
    20761 agtttgataa gatcatcggg ttagatcggc ttaaagtact ccatatcaat gattctaaaa
    20821 atccgcaagg ttcgcataaa gaccggcacg ccaatattgg ttttggaaca atcggattcg
    20881 acacgctgaa taagatcgtc catgatccaa tgtttgacaa tatttcgaaa atcttggaaa
    20941 ctccctatgt aggcaaagat aaaaagaaag cttacgcacc atatggaaaa gaaatcgcca
    21001 tgttcaaagc gcaaacattc gatccagaag tgtttcctga gttattagca gaagaagtga
    21061 tactctaaga ttttctatct gacagcagca aaaaaggacc aggcacattg ccttgtcctt
    21121 ttttgtttaa gaaacaaagg agtacttttt gcagtctttt tcatcatgca tcttctcccc
    21181 cctcttttta aatttagaca aacaaggtat actggtagaa aagtaaaaaa acgaaaagtt
    21241 tcacaagcaa gtggcaaaac gtgattggaa ggacgaaaag atgctgaaca ctttaaaacc
    21301 cttgatcaac caactaaaaa agaaacatac atactttatt cttggcatag ccctattatt
    21361 tacaattatt cgtttgtatt tatatagtaa agcaatctat ggaacagaca tgtcggcaac
    21421 ctatgatgac cagctgctga ttcgctatgc tcaaaatatt ttggacggta aatggctagg
    21481 ggagtatacg actacaacac tttccaaagg aatctcctac agcttatttt tagtacttgc
    21541 acataaactg catctttctt atgcagtttt gttcggcatg ttcagtattt ttgccagtat
    21601 attggttgca ctcgcgttta aaccgattgt gaagaacaag tatcttcttt taagtatcta
    21661 tttttatttt ttgttttctc cgattagttt tacacatgaa tattccactc gaacatatcg
    21721 taatgccctc gtgattccgg ctgttgagat cattatcgct tgtttattag ctatttatta
    21781 ccgcaaatac ggttctagca gaaaattgct gccatggttt ttagggcttt ctgtcgcttt
    21841 tcctttcttt tggttcattc gcgaagattc tatctggctt cttcctttta ctgtagtagc
    21901 tttgggtatc agtttcgtcc agatcttgct agggcaagac ttttctttca aagaagtaaa
    21961 gaagttaaaa aaacgactct ttcttctctc gaaacgggaa tggctgaaac tttcattgtt
    22021 tttacttcct atagttggct tttccatcgt ctatcaatgg atcgaatata aaaatgagac
    22081 aacatacggt attgcaacca tcaatgaccg ttccagtgga gaatttggac gtttgatgaa
    22141 acaactgatc cgaatagatg atgaaacgaa cttgaataaa gaaaacagtg agatatgggt
    22201 ctcacatgct gcactaaata aagcattagc cgcatctcct acattccata ctgtttctac
    22261 ccgtattgac gaattatata cgactcacgc gtggactcaa ggtggaaaag taaaagaatt
    22321 acccggagat atcatctttt gggcattgcg agatgtggta agcgaatctg gttattacca
    22381 aaacaatgca aaagaaacca atgatttttg gaaaaaagtc aaccaagaat tagaagaagc
    22441 ctatcacaag ggaacaatca aaaagaaaaa agagttctat ctgatgggat caggagatgg
    22501 aaagacgatg agtgatctgc caatcgtatt cgatttcctt caatcaggat acgcttatgc
    22561 atggcgatat aaagatttcc atcaaggagg aaattatagt ttcggaacgc aagaacaagt
    22621 caaacaggct caagaattat taaaccttcc gctaatggag aattggatcg atagtaatga
    22681 accgagaaca cctaatttcc aattaacaaa atcagcaaaa gtcgcgaatg tcatcataaa
    22741 aatttaccaa gttctggcta ttcccgtgct gattgcttca atagcaggga tattacttat
    22801 gatactagga accgtatttg caaaagctga tcgtgcctat tatagttcct ctttgattgt
    22861 ggtcaccgga ttaatactga cacaattggt ttttcttttc ggtgtctcat ggttttgttc
    22921 ttatgcgcca gaaaaaaagg actatttttt aagtgtctac actggtgcag gcgtgccatt
    22981 aacgcaattc atcgtagtaa caagcatgct agttttcagt aaattaaatc tgaaaaaagc
    23041 tttatcttct aaataaaaag acccttggta gctagatttt taacctaact atcaagggtc
    23101 tttgtgtgga aaaatcagtt tttattcgat ttcttctacc gtttcctgca aaagctgttc
    23161 atattttttg tttcctttat ataaatcacc aatcgtccat gccaacagga gaaggacaag
    23221 aacaatgatt acataagcga tgtgatcagc caatgctagt tgagcggaag tggcttgctc
    23281 gccgaagaaa ctttcgatct gtcctggtaa tcctcgtaag ttcaagtaag ttagactaat
    23341 cacagagaac cagccaagaa gttttacgat gaatgaattt ttaaatcggc tacccatctc
    23401 cgcttggctg ttggtcatca tcagtaaagg aatcatcgaa aacggcaacg caaaagccaa
    23461 gaacacctgg gattcattca ttaagttatt caaagcggca tgttcttcga tcgttccttt
    23521 tgtacttgta aacaaaacac aaatcaatac aggaatcaca gaaagcaatc gtgtgaccag
    23581 tcttcttagc caaatcggga tacgcatatg gatgaatcct tccatgatga cttgaccggt
    23641 caacgtacca gtaatagtag agttctggcc agaagcaaga agtgctacag caaataaagt
    23701 ggacaagata ccagattttg ctacagcaat caaaatacca ttgctcatag ctgatggatc
    23761 agataaagct tcatacagac caaaaaagga aggatcttgg acagaaccgg ttttgaagac
    23821 agcgacaccc atgatcaata gcagtgcatt gactagaaaa gccattgaca actggatatt
    23881 agaatcccaa gtagaaaaac gtacagcttg tgctacatct tcttcgtttt ggtgatcgat
    23941 cttccgagtt tgtgaaactg ctgaatgaag atataagtta tgcggcatga ctgttgcacc
    24001 aataatccct aaagctccag tcagcggagt ttcgccgccg atgaccggtg agtctgagaa
    24061 tgtatgactg ttagggataa agccagcaaa taaactgtgc caatctgggt tagacaagcc
    24121 aacttgatag acaaaaacga ataaaatgac gaaaattaag cagacaacca gtgcttcgat
    24181 cttacgaaac ccgacttttg tcagtagtaa gagaacgaaa acatctaata cagtaataaa
    24241 gacggcaatc accaatggaa tatcaaaaag taagtagagg gcgattgctg caccaatgac
    24301 ttctgcaata tctgttgcca taatggctaa ttcagtcaag atccataaaa tgacacctaa
    24361 tgtcttactt gtgcgtgctc ggattgcctg tgccaaatcc atttggctca cgattcctaa
    24421 ttttgctgcc atatactgta aaagcatagc aatcagacta gacatcaaaa taactgacat
    24481 caataaatat tggaaatttt gtcctccggt gatcgaagta gaccagttac ccgggtccat
    24541 atacccaact gctactaacg caccaggtcc agagtaagca agaagtgttt taaaaaaact
    24601 tttccccttt ggtacatcaa ctgttccatt tacttcagct aaagataaac catttgtatg
    24661 ttcaataagt cgatgcttat gaaattgttt attggattga ttattcaaga aaaaaccacc
    24721 tttcctattt atctacgatt acattctaca cctcaaaaag aaaaaattaa agaaaaagat
    24781 tcggtacgcc taattttttt tcatggcgcg tcttgctaga tgacgaaaga aattttgttc
    24841 tcctctaaaa aaaccactat tttttgcatg aaactaaaga atacgccttt cttttttcaa
    24901 taaactttag taaaataagt cattgagagc aattcggaaa tagaaaggag agatttatat
    24961 gttatcaaca ggtattgtcg tacttattgc tattattgct ttgctaatcg gcgcagtagg
    25021 tggctttttc ctagcgcgta aatatatgaa agactattta gaaaaaaatc ctcccgttaa
    25081 tgaggacatg ttgcgatcaa tgatgatgtc aatggggcaa aaaccatctg agaagaaaat
    25141 tcgccagatg atgcagcaaa tgaagaacca agggaaaaaa taggttctga cccaacgact
    25201 ttttacgggc tgattttttc agtccgtttt ttatttcgta atttgttaga ctattcagat
    25261 tattcagcaa aaaagacaag cacagacaat cctaggctct tgataaagac aaaggaggag
    25321 taaaatgtcg atttttagaa aattaggctg gttttttcgt caggaaaaga aacattattt
    25381 aattggggtt ttctcgctat tcgcagtggc cttggtacag ttagttcctc caaaagtgat
    25441 tgggatcatc attgatgaga tcgccgataa aaatttatca ataaagatca ttttcgggtg
    25501 gatcttccta ttgattatcg ctgctttttt acaatatctt tttcgttata tctggcggac
    25561 gaatatttgg ggaagtgcag ctcgattgga gaaagaactt cggcagcagt tattcaaaca
    25621 ttttacagaa atggacaatc tcttttacca aaaatatcgg actggggatt tgatggctca
    25681 cgcaacgaat gatttgaatg cgatccagaa tgtagcagga gctggtatct tgacctttgc
    25741 agattcagtg attacgggcg gaacaacgat cattgcgatg attttgttta ttgattggcg
    25801 cttaacactg attgcgctga ttcctctgcc tttgctggcc gtcacttcac gagtgctggg
    25861 gtcaaaactc catgatgctt ttcgtgattc gcaagaagct ttttctagta tcaatgataa
    25921 gacacaagaa agtatcactg ggatcaaagt cattaaaaca tttggacaag aaaaagaaga
    25981 tctagcggat tttgaagaaa agattgaaga tgcaattatt aaaaacaaac gagtcaattt
    26041 tttagactcc ttatttgatc cattcattac cttgattatc ggtctgtctt atgttgcaac
    26101 aattatttta ggtggaaagt atgtcttgga aggcacgatc tcgatcgggc agatggtctc
    26161 atttattagt tatatcggta tgcttgtttg gccgatgttt gcgattggtc gattgttcaa
    26221 cgtattggaa agaggaaatg cttcttatga tcgcgtcaat gaacttttgc atgaaaagac
    26281 gcatatcgtg gaacaactgg gtgcagtgca gaccccggca aaaggcgagc tgaatgtagc
    26341 tatttcctct tttaattatc cgaaagaaga atcaccagca ttagaacaaa tcaagtttgc
    26401 gatccaagaa ggagaaacat taggtattgt tgggaaaact ggtgcgggaa aaacgacgat
    26461 catcaaatta ctgatgcgtg aatacgatga ttatcaaggg aaaatccaat ttggcggacg
    26521 ttcgatcaaa gaatattcat tgaatgcttt attaggatca atcggctatg tgcctcagga
    26581 tcacttcttg ttttcgatga ccattcgaga taatatccgt ttttctaatc caaaactttc
    26641 agaagaagaa gtagagcatg cggcttcttt agcatttatc aacaatgaaa tcaaggaatt
    26701 accaaaaggt tatgatacct tagttggaga acgtggagtc tctttatctg gcggacagaa
    26761 acaaaggatt tcgattgctc gagcattgat caaaaatcct gaattattaa tattagatga
    26821 tgcactctct gcagtagatg ccaaaacaga agaagctatc ttgcataatt taaaagaaat
    26881 aagaaaagag aaaacaacta tcattgcagc tcaccgttta agtagcgtga tgcatgcaaa
    26941 agaaatcatt gttgtcgatc aagggaaaat cattgaacga ggaacccatc atgagctgct
    27001 tgcactaggc ggctggtatg aacaaatgtg ggagaaacag caattagaag cgaagataga
    27061 aggaggcgag gcctgatgga tgaaaattat caatcggaat ggacaaaatc gattccactt
    27121 aaagaacaga aaaagatcat caaacgactg atgaagttcg ccaaaccttt tagaagaacg
    27181 ttcatcgttg ctatcttatt tgcgtttgct ttgtctgtga tcaatgtcct attgccaagg
    27241 atcatccaaa cttttatgga tgatcatctg gctaaacagt cggctacgac acaagttatt
    27301 ttgttttttg ctggtatgta cttatttgga gtcatagtaa aaagtatcat ttggtttttc
    27361 caatggtatt tgtattccat ggcctcattg aagacctatc agtatattag ggtaaaatta
    27421 tttgaaaagc tgcatacact aggtatgcgt tattttgatc agacaccggc aggatcaacc
    27481 gtttctcgag tgacgaatga cacagaaacg ctatttgaat tttggtacgt ctttttgatg
    27541 gtattgactg ggatctttgc agtcgtttct tcattccttg ccatgtttca aatcaatgga
    27601 gaaattgcct tgtggacttt ggtgtttttg ccgattttag gaatcgtcat ctggtattac
    27661 cagaaattca gttctcgtat ttaccgaaat atgcgggaaa aattaagtca gctgaacacg
    27721 aaattgaatg aatcgatttc cggcatgcgt attatccagc agtttcgcca agaagctcgt
    27781 ttagctaaag aatttgaaca agtgaacaat gagtatttag acacgcgtta tgcgatgatc
    27841 aaaacgaatt cgattctgtt aagtccgatc atcaattttc tatatgcatt ggcgattgcg
    27901 ttggtgttga ctttgtttgg gatcgatgcg ttgcattctc ccgtagaagt tggactgatc
    27961 tatgcattta cgacctatgt ccagggattt tttaatccaa tgtctcaaat gatggacttt
    28021 ttgagcatct tcacagatgg gatggttgct ggtagtcgta tcttgaagat tatggatacg
    28081 gaagaatatg caccacaaca aaaccctgga gcagatcaaa tgattacttc aggtaagatt
    28141 gagtttcgca atgtaagctt ttcttatgat ggagagcaca atgtattaaa caatatctct
    28201 tttgttgcta atccgggaga gaccgttgca ttagtgggac acaccggaag cggaaaaagc
    28261 tcgatcatca acgtattgat gcggttttac gaattttatg aaggtcagat attgattgat
    28321 gatcatgaca ttcgagaata tccaatggaa gagttacgta agaaaatggg gctggtcttg
    28381 caagatgctt tcttgtttta tggggatatc gcaggaaata ttcggatgat gaatccagct
    28441 atcacagacg aacagatacg ccatgcggct gagtttgttc aagcaaacaa attcatcgat
    28501 gaattaccaa aaggatatca ctcaaaagtg atcgaacatg gtgccagcta ttctagtgga
    28561 caacgacagc tgatcacttt tgcgcgaaca atcgtgactg atcctaaaat tctagtattg
    28621 gatgaagcaa cagcaaatat cgatactgaa acagaaggat tgatccaaga aggattggca
    28681 aaaatgcgtc aaggacggac aacgattgcg attgcccatc ggctgtcaac gattcgagat
    28741 gcagaattga ttttagtttt agacaaaggt catatagtag aacgcgggaa tcatgaaaca
    28801 cttctagcgc aaaatggttt gtatgcagat atgtacaaac tgcaaagcag tggtatataa
    28861 aagatgttgt gacagtagaa ttttgaccta agcactagag tgaaaataaa acatagcttc
    28921 tcatattttt catctgtgag agttagtgtc gtagtcacca gatttaaaaa aagattcgac
    28981 agctagtcag aagtgcctaa tagccactaa gaaagcgttg acaaaagcat ttgctttcga
    29041 taatataaag aaaacgatac aacttggata gtgattgcct gatgcaagct aaacctgatg
    29101 agtctcccat ggtttcatgg acggcttttt gggtttttct ttttgttttg gatacagccc
    29161 tatacatcat ggaaaggagc aaaacatgct gattgagaaa gtactgaata acaacgtcgt
    29221 aataaccagg gatgaaagaa atcaggaaat gatcgtgatg ggaaaaggtt tggcattcaa
    29281 aaagaaagtg ggtgacccga tttttgactc atgcatcgac aaaaaatttc agttgacaaa
    29341 tgacgggctt tcacaacagt tccaagaatt ggcacaagcg attcctcttg agtacttaga
    29401 aatttcttgt gaaatcattg aatatacaaa agaggctcta caagtccagt tgaatgattc
    29461 tgtgtatatt gcattgacgg atcatttgta tacggctatc gaacgtcaca aaatgggaat
    29521 atttgtacca aatgtattgc tgtatgatat caaacaacta tttcctaaag agtatgccat
    29581 cgggaaaaaa acagtgaaga aaatctcgga taaataccac atcaagttat cagaagatga
    29641 agccggattt atcgcattgc atttagtcaa tgcacaaggc attcaaagcc agcaagacaa
    29701 tacctacctg tttactataa caatacagga tattctaaat atcgtccgct attactataa
    29761 gattacattt gatgaagatt cagtccattt ttttcgattc gtcacacact tacgtttttt
    29821 tctgacacgc gtcctagatg gagaaaaatc agaagtggga gaagtttctg aggaattgtt
    29881 tcaggttatt caaaaaaaat ataaggatac gtttggttgc gttgagaaaa tagcagactt
    29941 tttagccgag acgttcaact accagatgtc cacggacgaa aaaatgtatt taacgatcca
    30001 tactgcgcgt ttagtgcatg agaatcgttg taaataaaaa aaggaggata aattaacaag
    30061 aacgtatgaa ataagggtag tgacattcag ttggctaaac cttccactaa taaattggag
    30121 ggaatagaaa tgggaaaata ccaagaatta gcgagaaaaa tcgtagaaaa tgtcggcggg
    30181 aaggaaaata tcaatggttt gacacattgt atcacaaggc ttcgtttcaa attaaaaaac
    30241 gaagaaaaag caaatgatga gatcttgaaa aatatggacg gtattgtaac ggtaatgcga
    30301 gcgggagggc agtatcaagt tgtcattggg aatcatgtgc cagtcgtgtt tgaagaggtt
    30361 ataaaagcag gaaaccttac ttttgatgag gctgtttcaa cagaaaaaat gagaccgttt
    30421 gatatgctta ttgatggaat atcgggctgt ttccagccat tccttgctat cctagctgct
    30481 ggcgggatga ttcgtggact gacagcattc cttgtcttct taggcgcgtt tgaccgcggt
    30541 tctggcacat ttgttatgtt tgataatatc ggtgattctg tattccaatt tatgcctgtt
    30601 attatcggtt taacagctgc ccgtaaattt aaagtaaatg aattcgtagg gatgttgctt
    30661 ggcgcagcat taatgaatcc tagcttgtcg ctggaagctt tgagtggtgc agcagaagca
    30721 ccactaacga ccatattttc tggcactatt tttgaagcac ctatttatca aacagtattc
    30781 ggcattccct ggattgcgcg taactacgct tcttctgtca ttcccattat ctttattgtg
    30841 ttgttagcta gccaaattca gaaaccaatt aaaaagttag tacctgagat gatcgcgaat
    30901 ttcttcgttc cattcttcac cgttcttatt acaatgcctt taggtttttt actcgttgga
    30961 ccagtattca cattcgcaac tgatatttta atggctggat ttgaaacact tttagcactt
    31021 tcgccagtta tttatggagc aatcgtaggc ttcttctggc aaattctggt gatgtttggt
    31081 ctccattggg caatcgtacc aatgggattg atgcaatttt ctgtgaatgg ttggcaaaat
    31141 attatgacac ctgttgcagt agtgtctttt ggacaaactg cagcacttac cgcactctac
    31201 tttaagctta gaaatccaaa agacaaagca attgcaatac cagccattgt ttctggtatt
    31261 gtggggatta cagagccagc tatttatggg tttacattac cacgtaaaaa aatatttatt
    31321 tttacctgtg tcggtggtgc gttagggggc gcgtatagtg ggttaatgaa tttaacttct
    31381 tggaatcaag gtggactagg catctttaca attcccaact atattagacc agatggtgat
    31441 ttaacagatg tgattaatgt attgattggg atcgccattg cgatggtggt atcctttacg
    31501 ctgacttttt tcttttggaa ggatgaagca ggtgaaacag atgatataca gaaaaaatca
    31561 ggtaaagaaa ttgtaaaaac accgatacaa ggacaaatcg ctccactaaa tgcagcaaag
    31621 gatgcagctt ttgcacaagg aacactaggt cgaggaatct tgatctaccc tgaaaaagga
    31681 gaagtacgtg ccccttttga cggaacagtc atgaccctgt tcccgacgaa acaggcaatt
    31741 ggaatggttt ctgaaacagg gctggaattg ctgattcatg tcggattgga tactgtgcag
    31801 ttggaaggga aatattttga aagcttagtg cagcaaggat aaagagtgaa acaaggcgat
    31861 ctgttgctac gcttcgacaa aaagaaaatc gaaaaggaag gatacagttt agaaacacct
    31921 gtgatcgtca ccaattacac ggattatttg gatattttgg aaaaccaagg ggagacggtc
    31981 gggccagacg atgcacttat caccgcactg acctgaacgg ttaggtgaag aatggactag
    32041 gcttaactat tctttttatt ccacttcttt attttcaaaa ttgaaaggct ctttcatgat
    32101 ggctgagctg atagggcgtt tatcgaattt ttgaccgaca gaaattagat ggactaaatt
    32161 ctgttgataa ttttctgcaa aaacacaact atataacacg tctagaagat aacaaattga
    32221 tgtattgatc gtaaaattac caatttttga atacagtcgc tcgcgtgtcg taagtcgcaa
    32281 agcggctgta ctcattgcag atagcgttga atcaccgata ctggtcaaag ctaaaattgg
    32341 aacatgattt tgtttcaata tttctgcggt acgaaggatc acattgtttt cacccgtata
    32401 agaaatcaga atcccgcaca tatcactcgt gcaattgtac gcttcataga atgattcacc
    32461 aaaagtggtg acaatcgtga catccatttt gatgcgcttc attttcagca tgaaatcttg
    32521 agaaatcaaa gtattcgagt tactggcgaa aatcacgatt ttttttgctt gaagcattag
    32581 ttgtttggct ttttgcagtt ggtcatgatg aatgagagaa agtgtatcat gaatcgtcat
    32641 ctgttctaaa gaagccattt tatttgcgat cgtcataata ccgtctgtgg tggaaaaagg
    32701 aagattcgca tctacgtctt gaaaattccc ttcaagatag gctgtttcag ctaaaaaagc
    32761 attacgaaaa ctgacccagc catcaaaacc catttttttt gctacacgga tgagtgtaga
    32821 ggggtggaca taacatcgct cagcaatcgc ttggatggtc atttcgccaa gtgctggaga
    32881 atcgcttaag agaaactgga tcacttcatt ttctgaagga gaaaaggaga tttctttgat
    32941 tttttcacgt aataacatgt agataccttc ttcttatttt tttacgtaaa ttataacttt
    33001 tttgaaaatg atttgtaaac ggatttatac tatataactt aaaatagaca ttttttgaca
    33061 agatatttac aaaaatccac tagaaaacag taaattttgt aaatgttact ggaaagaaac
    33121 agatttctat tgtttgtttt gtttacaaaa aagataatga aagtgtaaaa aagtaaagga
    33181 gtgagaacat ggcaaaagga atcaaaatcg ctacgattgg tggaggcagc agttacaccc
    33241 ccgagttgat ggaaggattt atcaaaagat atgaggaatt accgatacga gaaatctggc
    33301 tcgtagatgt agaagaagga aaagaaaagc ttgagatcgt tagtcagatg tctcagcgta
    33361 tgtgggatgc ttctccgtat gaagtcaaga tctatgcaac tctggatcgg gaagaagcat
    33421 tgaaagatgc ggattttgtt acgactcagt ttcgtgtcgg tcaattagat gcacgaatca
    33481 aagacgagcg gatccctagt tattatggga tgattgggca agaaacaaat ggtgctggcg
    33541 ggatattcaa agcttttcgt accgttccag tcgttttggc aatcgttgag gacatgaagc
    33601 gtttatgtcc aaatgcttgg ctgatcaatt tcgcgaaccc aagtgggatg gtgacagaag
    33661 cagttatcag atatggcaaa tgggataaag tgattggatt atgcaatgtg ccagtgatgg
    33721 cgatgatgac agaaccagca atgcttggca agaaaaaaga agagctgatc tacaagtttg
    33781 ccggtctaaa tcatttccat tggcacaaag tagcagataa taaaggaaat gaccgcacgg
    33841 cagaattgat tgatcgttta tacgatgaag agaatggatt accgaaaaat atctttgata
    33901 tcccgttttt caaagaacaa ttaaaacaaa tgaacatgat cccttgtggc taccaccgct
    33961 attactatcg tgaagaagaa atgctggaac atgctttaga agaatatcaa acgattggta
    34021 caagagcgca gcaagtgaaa gaaacagaag cagagctatt tgaattatac aaagatccag
    34081 aattagacca taaacctgaa caattgcaaa aacgaggtgg cgcttattat tcagacgctg
    34141 cctgtgaaac gattgcttca atctatggaa ataaagaaac acagatcgtg gtatctacaa
    34201 agaatgatgg agctgttcct gacctgccgg cagattgtgt agtagaagtc actgcctatg
    34261 ttggcgcaca aggagcgaga aatgtagcgt ttggttctct tcctgctgct gaaagaggct
    34321 ggttgcaagt aatgaagaat atggaattgc tgacgatcga agcagctgtg actggtgatt
    34381 atgggacagc tttacaggcg tttacgatca atccacttat acgatcagga aagacagcaa
    34441 aacggatcat ggatgagttg tttattgcac accagcagta tttaccgcaa ttcaaggaga
    34501 caatcagccg attaaaagaa gaaggaatcg aagttcaaga tgaactggca agagaattat
    34561 caggtaatac acatataatg gaggaagtat aatgggattc agaaaagatt ttttatgggg
    34621 cggtgctaca gcagccaatc aatgtgaggg cggttatgat gaaggtggac gcggactagc
    34681 aaacgtagat gttgtgccaa tcggaaaaga ccgttttcct gttatcaccg gaaagaaaaa
    34741 aatgtttgaa tttgatgagg atcattttta tccagcaaaa attgcaatcg atatgtatca
    34801 tcgttataaa gaagatattg ctttgtttgc agaaatgggg ttcaagactt atcgaatgtc
    34861 catcgcctgg agtcgtattt ttccaatggg ggatgagaaa gagccgaatg aagctggctt
    34921 gaaattttat gaggatgcct ttaaagaatg ccaaaagcac ggaattgagc cacttgtgac
    34981 gattacgcat tttgattgtc caatgcattt gatcaaagaa tatggtgcgt ggcgttccag
    35041 agaactcgtt ggtttttatg aaaatctgtg tcgagtcatc ttcaatcgct ataaaggact
    35101 tgtcaaatat tggctgacat tcaatgagat caatatgatc cttcatgcac cattcatggg
    35161 cgcagggctg tattttgaaa aaggagaaaa tgaagaacaa atcaaatatc aagcggcaca
    35221 tcatgagttg gttgcaagtg ccatcgcaac gaagattgct catgaagtag atccggagaa
    35281 caaagtaggc tgtatgctgg cagcaggagc atattatcca tacacttgca atcctgaaga
    35341 tgtttgggct tctagaaaat cagatcgaga aaattatttc ttcattgatg tccagtcacg
    35401 aggagaatat cccgcttatg cattgaaaga aatggagcga aatggcattc agatcgaaat
    35461 ggaaccaggg gatgccgcat tgctgaaaga acatactgtt gattttatct ctttttctta
    35521 ttatgcttcc cgagtttcga ctaccgacaa cgaactcttg gaacagactg caggaaatat
    35581 ctttgcttct gtcaaaaatc catatctgca agcaagtgaa tgggggtggc aaattgatcc
    35641 attaggcttg agaataacga tgaatgatat ttatgatcgt tatcaaaaac cattgtttat
    35701 tgtagaaaac ggcttaggtg cagtcgatac gccagatgaa aatggttatg tggaagatga
    35761 ttaccgaatc gattacctgg cagcgcatat ccaggcgatg aaggatgcag tagaactaga
    35821 cggagtcgat ctattaggct atacgacttg gggatgtatt gatttagtat cagctggtac
    35881 cggtgagatg aagaaaaggt acggattcat ttatgtcgat cgtgataacc aaggaaatgg
    35941 cacattagcc cgttcaaaga aaaaatcatt caactggtat aaaaaagtaa ttgattcaaa
    36001 tggagaaaat ctttcgaacg attgatcaat gatttataaa agtctattgt ttttcagcgg
    36061 atttttcgag tataataaag ctattcgaga aacgcaagca gaacaataga ctttttttcg
    36121 cattggctgt aaagtatgct tacttgatta agtaaaggag aatctacata tgtatgatgt
    36181 aatcgttatt ggcgcaggtc ctgctgggat gactgctgct ttatatgctt cacgttcaaa
    36241 cttatccgta ttgatgatcg aacaaggtgc ccctggcggc caaatgaaca atacggcaga
    36301 aatcgaaaat tatcctggat tcgattcgat catgggcccc gatctagctt ataagatgta
    36361 tgaaagtgtc tcaagatttg ggacagaaaa tgcttatgga atcgttcaag atatcaagga
    36421 tcacggcagc cataaagaag tcatctgtga agataaaagt tacgaaggaa aaacagtcat
    36481 tatcgcaaca ggatgtatcc accgtaaatt aggcgtacct ggcgaggaag aatttgctgg
    36541 acgaggcgtt tcttactgtg cagtctgtga tggtgcgttt ttccgtaaca aacgtctagt
    36601 agtcatcggg ggtggggact cagcagtaga agaagccatc tatttgacac aatttgcttc
    36661 tgaagtagtg atcgtccacc gtagagatga attacgtgca caaaagatca tccaagaccg
    36721 tgcatttgca aatgaaaaaa tttcctttat gtgggataca gtcgttgacg aaatcgttgg
    36781 aaacgaaatg gtagtgacag gtgtgaaagc acgtaatgtc aaaaccggca atgaatttga
    36841 tttagcagca gacggagtat tcatctatgt tggactggat ccattaactg caccttttag
    36901 agaagcaggt ttgacgaacg aagctggctg gattccaaca gacaacgaaa tgaaaacgaa
    36961 tatgccaggc gtttttgcca tcggagatgt tcgtgaaaaa gatttgcgac aaatcactac
    37021 agctgttggt gacggcggta ttgctggaca acaagtgtat aaatacttgg agtctttaga
    37081 agaaacaaca gcataagttt aaaaagagta gaagaacggg ttcaattgtt cttttactct
    37141 tttttttcgc gtgaaattta ctgaatctga tttatgcgaa cacgtccaac accttttgat
    37201 aaaagaatcc tttcttgatt taagcgtttt ttggtcctca tactttcata tctaataagt
    37261 gaatgctata cttattaaga accatatttc agaaagaggt gttattttca tgtcttggga
    37321 acaagtgtat gaacaatggg tacatgaaga aaatttagaa gaaaacttaa aaaaacaatt
    37381 aaatgatctg ggtgaagatc ctgaaaaact tgaagatgct ttttatgcac cgttggaatt
    37441 cggtactgca ggtatgcggg gaatcttagg acctgggatc aatcgaatga acatctatac
    37501 ggtaagacaa gcaacagaag gactagcacg tttcatggat acacaaggtg aagaaacaaa
    37561 acgccgaggt gtcgctatcg cttatgactc acgccatcag tcaccagaat ttgcaatgga
    37621 agcagccaaa acactagcac atcacaatat cccgtcttat gtattcgaaa gtctgcgtcc
    37681 aacaccagag ctttcttttg cagttcgtca tttgaagacg tttgcgggaa tcatggtaac
    37741 cgcatctcac aacccagcgg cttacaatgg atataaagtc tacggagaag atggcggaca
    37801 aatgcctcct gcagacgcag atgcattgac gaaatatgtc cgtgaagtca gcaatccgct
    37861 aaaagtcgaa gtattatctg acgaagaagc taaacatagc gggttgatca cgatcatcgg
    37921 agaagaagtg gacgctgctt atctagaaga aatcaaagca gtgacgattg atcgtgaatt
    37981 ggttgaaaca atggggaaag atttgaaact tgtgtacacg ccacttcatg gaacagggaa
    38041 aatgttgggc gaacgtgcgt tgaaacaagc tggattcgaa caattcgtac tagttcccga
    38101 acaagctgtg gcagatccag atttcactac ggtcaaatcg ccaaatccag aagaacattc
    38161 agcttttgaa tatgctatac gacttggaga aaaagaagga gctgacttgc tgattgcaac
    38221 agatcctgat gcagaccgtt taggcgcagc ggttcgtttg ccagatggtt cttatgaagt
    38281 attgactggg aaccaaatcg gagcattgtt tgctcaatat attttggaag cacatcaatc
    38341 aagaggcact ttaccagaaa acgcagcggt attgaaatca atcgtttcca gcgaattgcc
    38401 tacagcaatt gcggaacact acggtgctac catgttcaat gtgttgacag ggtttaaatt
    38461 cattgctgaa aaaatccaac aatttgaaga agaccattca catactttta tgtttggatt
    38521 cgaagaaagt tatggttatt tagttaaacc ttttgttcgc gataaagacg cgatccaagc
    38581 attgctttta ttagcagaag tagcagctta ctataaaaaa caaggcaaaa cgttgtatga
    38641 cggcttgcaa acgatttttg aaacctatgg ctatttcgca gaaaaaacga tttctgtgac
    38701 aatgagcgga caagaaggtt ctgcgaaaat ctctgctttg atggaaaaat tccgtaaaga
    38761 agcaccgaca gaatttgccg gagcaaaagt tattcaaaca gaagacttta aagaattgac
    38821 gagaacagac cgtgaaggaa acgtagaaaa actaacaaca ccgccatccg acgtattgaa
    38881 gtatacattg gaagaaaatg gctggatcgc tatccgccct tcaggaactg agccgaaaat
    38941 caagttttat attggtgtaa aaggaagctc tacagaagac gcagccgaaa aagtagcctc
    39001 ttatgaagcg attatcaaaa agatgacaga agaataaaaa acttgagact gatggaaaaa
    39061 gtggtaaact ttagaagtca gtcttttttc aagttggagg tgaatggatt gccagacacg
    39121 caaaaatcaa aagtagagaa agtcagtcaa ttattcaaaa tgttgagtga tcccactcgt
    39181 cttaaaattc tgctatatct gaaagacggg gaacaaaatg tgacagcaat cacccaagca
    39241 gtggaaatgg agcagtctgc tgtatcgcat caactacgtt tattaagaga aaatcatgtc
    39301 gtcaagtctc atcgcgaggg aaaagcgatt ttgtatagtc ttgatgattc tcatgtactg
    39361 gatattttga accagacact caaacatgtg gaacatcaat aacgataggt gaaaatagat
    39421 aaacactgga gtgtgacaac gaagaaattt cgttgtcaca ctccagtgtt ttttaagaaa
    39481 aagacaaaaa tgattaatcg cttttttctg ttgtttcagt tccataataa ctatgatctt
    39541 ctaggtctaa agcattcaaa ataagcgaag ccgtttcttc aatagataaa gatgccacat
    39601 tgatcactac acatcctagt ttttcataaa gatcattcgc aaaatcgagt tcagctctaa
    39661 ttttttcgat atcggaataa gcagtatcag ggtttaatcc gtaagagcgc atccgttctt
    39721 tacggatatt atttaaaata tctgggttat tcgttagtcc cacgattttt ttaggatcga
    39781 tttcccacag ctgtttggga atatgtgctt ggggaatcaa aggtaaatta gcaactttta
    39841 aatttttatt tgctaaaaac aagctcaaag gcgttttgga agttcgggat acgcctagca
    39901 aaacgacatc tgcttctaaa aaaccacgag gatctttccc atcatcgtat tttacagcaa
    39961 attccattgc tttgatccgt ttgaaatagt tctcattcaa taaatggagg gcaccaggtt
    40021 gccgaattgg cttgatacca gttaaacgtt caatttctga tatcggtggc gtcatcacat
    40081 cgaaactaaa taattgatgt tcttcacaaa aagaacgtgt tatctcgatc agttcttgat
    40141 tgattaatgt atgcaggaca agtgcttttt cttctaatgc atcttgcaat gcctgcctta
    40201 atgttttttc atctgtcacg aacgttctgc ggaataggtt gaactcaacg gtaggatact
    40261 gagccatagt agcttgcgct agttttgtcg cagtttctcc agcagagtcg gagatgacaa
    40321 aaaaagtaac gatttctgta gaatcggaag acatggataa aacctcactt gcattttttt
    40381 tatgtttatt ataccatact ctagaatgcg tacttcgtaa tcattttgat ttggaggaat
    40441 aagtcatgaa aaaacagaca ttgatcgaac aatcattaga aacattgaaa aataacggtt
    40501 ttaaatatac taaaaaaaga gaagcattgt taacttattt agtgaagcgt aaccgctacg
    40561 tatctgctaa agaagttttt gactatatga atcaggaatt caaaggggta agttatgata
    40621 cgatttaccg gaatctccat gattttgcag agatcgattt actggaagaa accgatttaa
    40681 atggtgaaat gaagtttcgt tttcattgct gtcaggggga aatcggccat caccatcatt
    40741 ttatctgtac agtgtgcgga acaacgaaag aaatccatat gtgtccaatg aattatttcg
    40801 aagaacagct aggtggatgc acgatcgaag ggcatagatt cgagattttc ggaagatgtg
    40861 aaaattgtca ataaggattt aaataaaata acatttgata atttaaaaaa aaaagcaaga
    40921 tttccttgac ggtcaaaaca gcattagata taatatttac aggacagtct tgttttttga
    40981 gatatatttc aataacaatt acggttactt tttaagctcg gagggaggga attaacatgt
    41041 caaaaacagt cgttcgcaaa aacgaatcac ttgacgatgc tcttcgtcgc ttcaaacgtt
    41101 ccgtgtcaaa agcgggtact ttacaagaat ctcgtaaacg tgaattctac gaaaaaccaa
    41161 gtgtaagacg caagaaaaaa tctgaagcag ctagaaaacg caaaaaattc tagttctgtg
    41221 atgaattgga gttggtagtg tgtcactact aagtagatta aacgatgaca tgaaagcagc
    41281 gatgaaagcg aaagataagg aatctttaca agtcatccga atgatcaagt catctataca
    41341 aaacgagcag attaaagaag gtcacgactt gacagaagaa gaagaactaa cggtgttgtc
    41401 tcgcgaaatg aaacagcgac gtgattcttt gcatgagttt gaagaagcag gacgtgacga
    41461 tttagctgaa aaagtaaaaa gtgaaattgt aatagtcgaa aaatatatgc cggaacaact
    41521 ttccgacgaa gaaattcgac aacttgttca agaagcaatc actcaaactg gtgcttcatc
    41581 aatgaaagaa tttggcaaag ttatgggtgc aattatgcct aaagtcaaag gaaaagcaga
    41641 tggaaaccaa gtgaatgcga ttgtgaaaga actattacaa tcttaatttt atcatttaaa
    41701 ctgcggacag tgattgtccg cagttttttg tgttcgtaaa aaaagaacta aaaaacagct
    41761 agaagaaaga ataagattct ttcttctagc tgtttttttc ctgtttaata tctcttatgt
    41821 taaattgtgt ttgatttggt tattcttctg gtagttcatt tgcttcttgt ttataccctg
    41881 ataggcgata ggcgtaataa aagagtaagc tgccagcgta accaagtaac gttgggacca
    41941 tccagccaag tcctaatgca gcaaaaggaa cgtgatgatg ataaaatcct agtaagcttg
    42001 ctacgacagt ttgctgactc actaatgcag gcgaatttgc caacatatcc aatacggctg
    42061 gaacggcaga aaagaacatc gttacttgat agacaaatgg actcttttgg aagaattttg
    42121 ctgttaagga aagcaagatt aacgcaagtg acaatggata caaaagcatc aatactggta
    42181 aagaccattg gatgatatta tccaatccgg cattcgcaac gacaaaagag acaaaagtcg
    42241 ttaaccgcag ccatgtcata taactgactt tagggaacag tttatggaaa tcttgtgcaa
    42301 aagaaacaac gagtcccata gcggtagtga agacacctaa tgtgaccatt acccctaaga
    42361 agctagcacc gaagttacct aaataaaaat tagtgatctg agaaagtgca gttccgccat
    42421 tttctgataa agacatctta ttcaaactca tcgcaccgag aaggaccaga ccaaaataaa
    42481 tcatgacttc taacgcaacg ctcaggctac cagcttttgc tgttaattct gtgacttttt
    42541 tatctttaaa accaagatca cgaactgcat ggacaaaagt gacacttaaa gcaagtaaag
    42601 ctactgcatc aaccgtgttg tatccttcta aaacgccatt tgtcaaagcg ttcgtctgat
    42661 aagaatctgc agcagattgg tttagattcc ccatgggttg gaataaagaa acgacaaaaa
    42721 tgatagctaa taatgcaaga aacaaggagt ttaaatactt tccgacatat ttgaccaaac
    42781 gtgttggatg tacagtaagg aaataagcaa gtaaaaagaa aagagcagag aataaaaaca
    42841 tacctaatga atcatatttt tcaggcaaaa agggtttagc agccatttca aaagcagttg
    42901 ctgctgtccg cggtgtacca aagaatggtc cgatcgttaa atgaacaagg atcaagaaca
    42961 aggcagcata ccattttccg acaggtttag ctaagtcata cagaccatca ctttttgtca
    43021 ctactacagc taagatagct aataatggga aaagagcgcc tgagatggca aatcctacac
    43081 cagcgctgat ccagtttgat ccagccattt gacctaagtg gacaggaaag atcagattac
    43141 ctgacccgaa gaacatcccg aagataagtg aactgaccat caataattgc ttccatgaat
    43201 aagtttttgt ttcttccata aatttttcct ccaataatta tcattttgag taacaaaata
    43261 aacgttgcag aaactagaaa tgccactaat atcagattcc atgaaaacca ccaccttaaa
    43321 atataaaaaa aagccctttt ccacttggga aaagggctct agattctaga acggtaccac
    43381 cttttttcgc ttaaaaaagc ttcttcattc acggacgctt ttcgataaag ttatccgcta
    43441 gcctgataat ggaggcagcc acaatgatct acgttttcga cattgactcg gaaatgatgt
    43501 tcgtctattc gatttattgt catttctcac ttacatgact cactgggaat aaatcgctga
    43561 atagcctact gttttcctcg acgctttgct gtatatttat ttgttgacgt tataatacac
    43621 ctgttttttt tgaaatgcaa gaatatttca aatattttgt tttctttttt tgaaacaaga
    43681 aaaataccca gagaatactt gctaagttag acggaatact tgtcctctat cttatgcata
    43741 gcttacatga tcagcttttt ttattcaaac gagaccttta gagaatggaa gcagctattt
    43801 tttaacgttt cttggtactt atggttaagc aactctttta gaaccttttc ttatttgcta
    43861 tatagtttct tctgagtatg gtaaaatagg aaagaatgaa tcgaaaaaaa ggggatgtct
    43921 atttttgacg gaagagtcta gttctttaga gattagattg acggctgctg atgatgtcag
    43981 catgctttta ggtgcacacg acaagcatat aaaactgatt gaagaaacaa cagaaacaac
    44041 catccataca cgtggagaaa tcattcagat cattggtgaa caatcccaga tttccttggc
    44101 tgcctcagtc attcggacat tgcaggaatt gatcaaacga ggaatccatg taagtacacc
    44161 agatgtcgtg acggcactga aaatggggca aaaaggcaca ttagattatt ttgttgagat
    44221 gtatgaggaa gagatcgtca aagaccgtaa tggaaaacct atacgggtaa aaaacagcgg
    44281 ccaaaagaaa tatgtcgaat cggtagccaa acatgatatc gtatttggcg taggaccagc
    44341 cgggacagga aaaacttttc ttgcagtagt attagcaatc gctgccttga aaaaaggtga
    44401 agtgcaaaaa atcattttga cgcggcctgc tgtggaagca ggggaaaatc taggctttct
    44461 tcccggggat ctaaaagaaa aagtagatcc ttatctgcgt cctgtttatg atgctttata
    44521 ccaaattttt ggattagatc atacgaaccg attgatggaa cgaggcgtga tcgaaattgc
    44581 tcctttagct tacatgcggg ggcggacatt ggatgatgca ttcgttattt tggatgaagc
    44641 acagaacacg acagttgctc agatgaaaat gttcctgaca cgtcttggtt atcaatcaaa
    44701 aatgattgtc aatggagata cgagtcagat tgatctgcct cgagggacaa caagtggtct
    44761 tgttcatgca gaacgaacat taaagcaaat caagaaaatc gattttgtta attttgaagc
    44821 aagtgacgtt gttcggcacc ctgtagttgc cgaaatcatc aaagcttatg aaaaggcaga
    44881 tctccatcaa gaataagctt tgcttaggag gataagcaca tgttgaataa aacactgcag
    44941 aaactacaag aaaaacttgg aaaggcagca ttgcctttcc tgctgttctt gttttttatc
    45001 attatctgcg gcgttacatt tagtagtgtc aaacaaaagg ccaatgattt cagagaaggc
    45061 caagtagcag aagaaagtat ccgtgcaaac aaaacgatcg agaacacgga agaaaccgaa
    45121 caaaaaagaa aactggcagc agaagcagtc actccagaat acacttacca aaaagatctt
    45181 gcagatgacc agaataatcg gatcaagcaa ctatttgaat tgatcgataa gacgaatgat
    45241 gccatcaaca aatcttatga cgaaaagatt gataaggcaa aggaagatga aaatatccca
    45301 aagcctacta cagaagagcg gatcgccgcg ttgaagaaaa attttgaaaa tgtgaatgca
    45361 gaaaatgttg cgttttatca aaaactaccg aacaattttt attcgacgat atttgaaatg
    45421 actgaaactg agatccatac tgtgagggat gagagtctga agctcattga cgaacagatg
    45481 agcaaacaag ttcgtgaaag tgaattggaa gcttttaaac aagaagcaga agagcaaatc
    45541 caatatttga atgtcacacc agcacaacaa caaatgattc gctacttagt ggatcaaggt
    45601 atcgtagtga atgacgtatt gaatgagaaa aagacagaag aattgaaaca atccgcacga
    45661 gaagctgtac aaccagtgat gatcttccaa ggagaaatca ttgttcgtga aggtaatcaa
    45721 atcgatgctt cagctatgaa aaaattggaa ttactaggac tgactaatca aacaacttcg
    45781 atttttccgc taattgccat ggttttagct gttttgcttc aaatcggcgt actgatttat
    45841 aattcacttc aattccaaaa tgcaggagaa agaacaaaat acgtgctttt ctatgtgaca
    45901 gctatgtcag tcagcatagt gctgatgaaa tttttccaat tattccaaac ggaacaagct
    45961 acttatatcc cgctgtttta tcccgctgct tttgcaccac ttgttttaag ctttttcttg
    46021 aatcgaagag cagggatcat ggctggtatt ttccaagcag tatctgcact tttcattttt
    46081 tatgattcga ttggcacgaa ctttctaacg attatcttga tgtcttatgt tttctctggg
    46141 ctcatggcaa cgattgtcag acgtaaacgg atctcagaac aaggattatc tgctgccatg
    46201 tgggtcatta tttttcctgt gatgatggat gtcattttga tcgtctatca aggaatgagc
    46261 tttggtgatg caacgacttg gttaatgctc gtctgcgggt tcactggtgc actcttctca
    46321 ttcttgctga cgatcggtct acacccatat attgaattga tggtcaatga tgacagtgta
    46381 attgtattaa atgaactcag caatccaaat catcctttat tgaaacagtt gctggaagaa
    46441 gcgccaggta cttatcatca tagtatgatg gtagctaatc taagtgctaa cgctgtagca
    46501 gaaatcggcg gacgttcttt gctaactcga gtagcttgct attatcatga tatcggcaag
    46561 atcaaacatg ctagcttttt cgttgagaac ttgccttcag gagcggaaaa cccgcacaat
    46621 ttcttattgc cagaagacag taaacatatt atctttggac atgtgacaga tggagccaaa
    46681 atattggaag attataatat gccacaaatg gtgatcgata tttgcagaca gcatcatgga
    46741 accacgctaa tgcgttattt ctacatcaaa gcgaaagaac gcaatccgga agtaacagaa
    46801 gagcaattcc gttaccctgg accaaaaccg caaagtcgtg aagcagggat cgtcaatatt
    46861 gctgacagtt gtgaggctgc agtacgggca atggatcatc cgacgagcga aaaaatcgaa
    46921 agttttgtcc ataatcttat cgaagagcgt atttccgatg gtcaattaga cgatagtgga
    46981 ctgaccttga aagaaatccg aaaagtggaa aaatcattga tcagcggttt aagtagcacc
    47041 ttccattctc ggatcaaata tcctaaaatg aaaacagaag ttgagaagat aaaggaagaa
    47101 caagaagaat agaaagaagc gatgtataat ggatattacc tttatggatg aaacaaacca
    47161 agtctcagaa gagaaaatga aagaaatcga tgacttgctg caatttgcag catcttattt
    47221 aaagctgcca gaggaaacag aaatgtctgt tactttcatg gacaatgcgg caatccaagt
    47281 aatcaatcgt gattaccgtg gaaaagatgc accgacagac gtcatcagtt ttgctctgga
    47341 agaagaaggc gaagacgaaa tcccagtgat ttttgaagat ggagagaatc cattgcctcg
    47401 tgtactagga gacatcatga tctctattga acgtgctgct gaacaagcag aagcttacgg
    47461 ccattcatat gatcgggaac ttggcttttt agcggtacat ggattcttgc atatcaacgg
    47521 gtatgaccat atgacaccag aagatgagaa agaaatgttt ggtttacaga aagagatctt
    47581 ggatgcctat ggactcaaaa gataaaaacg tagagaaaaa caaacatttc ctgatgtctg
    47641 tggaatttgc tgtccaagga gtcaaaaccg tttttgagga agaacgcaat atgaggaaac
    47701 atgttgcgtt cggtatcctt gctttattta tgggcgtgat tttccagctt gatcggatag
    47761 agtggttatg gctgctttta gctgtttttc tcgtttggat agtagagatc atcaatactg
    47821 tttttgaaaa tgtagtggac atgtttacgg attttcattt tcatccgatt gggaaaaaaa
    47881 tcaaagatat ggcagctgga gcagttttag tgaccgcttg ttttgctgtc atcattgggt
    47941 tgattttatt tgtccctaaa atatatcatt tgttgtttaa ttaaaaagga gaacgtatat
    48001 gccagaacat aaatcagggt ttgtcgcaat cgtcggccgc ccgaatgtag gaaaatccac
    48061 attattgaac cgaatcgtgg gtcaaaaaat tgccattatg agtgacaagg cacagacaac
    48121 tagaaataaa atccaaggag tatatactac accagaagct cagctgattt ttatcgatac
    48181 accaggaatc cataaaccaa agcatcgtct aggagatttt atggtagaag cagcttacag
    48241 tgcgttgaaa gaagtggatg cagtcttatt tatgatcagt gctgatcaaa aacgcggtcg
    48301 gggagacgat tttattattg aacgtctaaa aaacgtgcat tctccagttt atctgattat
    48361 caataaaatc gataagatcc atccagacga gttgctggga atcatcgaag attattcgac
    48421 gcagatgcct tttacacaag tgattccgat ctctgctaca gaaggaaaca atgtcgaacg
    48481 cttaatggat gtattagtca gtgaaatgcc agagggccca caatattttc cagatgatca
    48541 agtgactgat catcctgaat acttcatcgt ttctgaattg atccgtgaga aagtcttgtt
    48601 tttaacacga gacgaagtgc ctcattctgt cgcagtcgtt gttgattcga tgaagcgaaa
    48661 cgagaatgat aaaatccata tccaggccac gatcatcgtc gaaagagata gccaaaaagg
    48721 aatcattatc ggcaaaggcg gaaaaatgct gaagcaagta ggaacgaaag caagaaagga
    48781 tatcgaaaat cttttaggag acaaagtatt tctagaactt tgggtcaaag tccaaaaaga
    48841 ctggcgagac aaaaaagtct atctgcaaga cttcggctac cgaaaagatg aatactgata
    48901 ttctgaactt cttataggtt aagtatagaa ataaactgga taaaaatccg cacgttgaga
    48961 aaaacggcgg aagatcgaaa cataaataat ctggatcggc agaatctgct tttccagatt
    49021 tattttttag gagggagaat atgagccagc ttgcagaatc gaaaggcttg attttatcta
    49081 gccgtaatta caaagaaaaa gataaattag tcaaaatctt tacggaatct tctggcaaaa
    49141 tgatgtttta tatcaaagga atccatcggc aaaatcagcc attagctccg gctttgctcc
    49201 cctttaccga agcagtctat atcggtaatt ttcgaagtga aggtttgtcg tttttaagca
    49261 gtgtcaaaga cgtccatgcg tttcggaaca tccaagaaga tatctttttg agcggttatg
    49321 gtacctattt gctaaatcta gtagatgcag caatcgaaga tcatcaatat gacccgcatt
    49381 tattccaatt tacgcaacaa gctctgcaac ggatggatca aggagatgat gcagaaatca
    49441 tcacgaatat ctttgaagtt caaatactgc aacgcttcgg aatcgcgcca atttggacgc
    49501 actgtgtcgt atgcggggaa acaaaaggaa aatttgacta ttcttccaaa tatggcggtg
    49561 tgatatgcga gaaacactgg ccaatggacg aacaccgtta tcatgcagat cctcgcgctg
    49621 tttatttcgt tcgaatgttt tcggctattt cttatgataa gatcagtgga atccacttga
    49681 aagaagaaac gaagcaggca atccgtgacc tcattgacca gttgtatgat gaatatgtcg
    49741 gtattcatct aaaaagcaaa aagttcattg atcaaatgaa gtcttgggca cacgtattaa
    49801 agacgccaga gaaaaacatg cctgaaaaag agatacctga aaaagaagaa taaatgaaag
    49861 atacaacaaa aaaatcaaaa ctatttgaca aatacaggga cttccgtcta ttattaaccg
    49921 tagattaaat agattgttca ctgagaggat ctattataca aacaagaaaa ctgcaaaatg
    49981 aatacgtaca ttgaccaaga tcagtaaaaa acacgtggtt tagcgagttc gggagagtgg
    50041 aagccggacc caaacgattt ttgaagaggc acttgcgagt acgataaatg aagctgccga
    50101 atctttattc ggaagtaggg tggaaccgcg aaattattcg tccctatgtc tgtaatcaga
    50161 catagggact ttttgtcgtt ttctttcctg tattcttatt gacagcaacg cttaaaaatt
    50221 gaaaggggca aaacagatga gtaaaaaatt gaccgtccaa gatatgattt taacattaca
    50281 aaaattttgg tcatcaaacg gatgcatgct gatgcaagct tatgatacag aaaaaggagc
    50341 aggtacgatg agcccatata cattcttacg ggcaatcgga ccggaaccat ggaatgctgc
    50401 ttatgtagag ccatcccgcc gaccagctga cgggcgttat ggagaaaacc caaaccgttt
    50461 gtatcagcat catcaatttc aagtcgtaat gaaaccttca cctgaaaata tccaagagct
    50521 ttatttagaa agcttgcgtc ttttaggaat tgatccatta gaacacgata ttcgttttgt
    50581 tgaagacaac tgggagaacc catcgatggg gtgtgccggt gtgggttggg aagtatggct
    50641 tgatgggatg gagatcacac aattcacgta cttccagcaa gtcggaggac taccttgtaa
    50701 accagttact tctgagatca cttatggact agaacgtctt gcttcatata ttcaagaagt
    50761 tgaaagtgtc tatgatctgg aatgggctga tggcgtgaaa tatggcgaga tcttcaaaca
    50821 accagaatat gaacattcca aatattcttt tgaagtaagc gaccaagact tgctactaag
    50881 taattttgac cgttttgaaa aagaagctaa acgctgtatc gatgaaaatc ttgttcatcc
    50941 agcgtatgat tatattttga aatgcagcca tacattcaac ttattagatg cccgaggtgc
    51001 agtatccgta acagaacgag caggttatct ttcccgtatc cgcaacatgg ctcgtgctgt
    51061 agccaaaatc tttgtggcag aacgcgaaaa attaggattc cctttattga ataaaaacac
    51121 agcaaatcca gaaaacatga aggaggctga ataagatggc aaaagactta ttacttgaaa
    51181 tcgggctgga agaaatgcct gctcatgttg tcacaccaag catgaaacaa ttagaagaaa
    51241 aaacagcaaa atttttagat gaaaaccaat tgacttatga tacgatcgaa acattttcca
    51301 caccgcgccg tttagcaatc aaagtaacaa atattccaga acgacaagcg gacagcgaag
    51361 aagaagtcaa aggaccagcc aaaaaaattg ctttggacgc agatggaaac tggacgaaag
    51421 cagctgaagg atttgtccga ggacaaggtc tgacgacaga tgctatcact tttagagaat
    51481 taaaaggcgt ggaatatgtc tatgtaacga aatacactca cggcaaagaa gcaaaagaag
    51541 tattgacagg tttagcagat gtcattaaaa gcctcacttt cccagtaacg atgcattggg
    51601 cagaatacga ttttgaatat atccgcccta ttcactggat cgtggcattg ttagatgacg
    51661 aagtaatccc attcgaaatc ttggatgtca aaacaggcaa agcctctcga ggtcatcgtt
    51721 tcttaggcga agatgtaaca tttacgcatg caaaagaata cgaagaaaaa ttaaatgaac
    51781 aatttgttat tgcttcaccg caaaaaagaa aagaaatgat catcacacaa gcaaacgaat
    51841 tagcagaaaa aaatcactgg atcattgatc tagatgaaga tttactagaa gaagtcaaca
    51901 atctagtcga atatccaact gtcttttctg gcgacttcga agaaaaatat ctatctgttc
    51961 ctgaagaagt actagtcact tctatgaaag aacatcaacg ttatttcgaa gtacggaacg
    52021 atcaaggtat gttgcttcct cattttattt ctgctcgtaa tggcgatcgg gtaaaattgg
    52081 aaaatgtggt acgaggcaat caaaaagtat tgactgctcg tttagaagat gcggaattct
    52141 tttataatga agacaagaaa gcttcaatcg accaatacgt tgaaaaatta aaaactgtta
    52201 ctttccatga aaaaatcggt agcatctatg agaaaatgca acgggtacaa gtcatcgctc
    52261 gcatcatagg cgaacaagta ggactatctg aggaagaatt gatggatctg caacgcgctg
    52321 ctgaaatcta taaatttgat ctagtaacca acatggtagg agaattccct gaactacaag
    52381 ggatcatggg agaaaaatat gctctgctta aaggcgagaa accagccgta gcaacagcga
    52441 tccgtgaaca ttacatgcct atatccagtg aaggagatct acctgagact acagtaggtt
    52501 ctgttttagc gattgctgat aaattagata gtatcttttc tttctttgca gttgggatga
    52561 tcccaagtgg ctcaaacgat ccatatgctt tgcgccgtca agcatatggt gtcgttcgaa
    52621 tcatcgaatc gaaaaaatgg gcctttcctt tgtctgttct gcaagaaacg attagtgaag
    52681 ttatcagtaa agatacggat cgttttggca ttggcttgtc agcgggacaa caacaggtga
    52741 tcgactttat caaaggccgt ctgcgccaat tattgacaac taagaatatt cgtcatgatg
    52801 tcatcgaagc tgttttgaac gcagaacaaa aagatctgac aaaagtattt gcagcagcac
    52861 aattgttcaa gcagcatctt gcagatgaag acttcaaacc atcgatggaa gctttgacac
    52921 gtgtcgtgaa cttagcgaaa aaagcggagc ttgaaaaaca atcagaagta gaccctgaac
    52981 tgttcgaaaa cgaagcggag aaagaactgc acaaagcagt agaggcaatg aaaacaagct
    53041 ttgctgacca aacgatcaac gaaaattatg atcagcttgt aagccttcgc ccactgatcg
    53101 aaaattattt tgatcagacg atggtcatgg cagaagaacc agcagtacgt aagaaccgat
    53161 taacgcaatt aagtcaaatt gctgccatgg ctttgtcact agcaagttta gatcaaatca
    53221 tcacaaaata atttctaata tgtaaataaa ccagagaaca ggcacaaaat aggctatttc
    53281 tctggtttat ttgttataaa tataaataac tattattaat tcaatgttaa ttttttttgt
    53341 tattttattt tttgtgtaac ttttaaaaac acctatgaaa attaaggaaa taaaaatgaa
    53401 atcgattaat tgttatctta ttaatgtttt atttattttt aaatcgtaaa ttgccctagt
    53461 caagaaaaca gtttgtggta tgattatata gggaaaactt gtttacaaat atttctgtga
    53521 atatattagt ttaattatgt tttttaaaat aaaaagctgt catttttatg taagtgaatt
    53581 atatcttaat ttatctatca tcaatactta ggagtgaatc tatggaaaag ccattcgtca
    53641 agtcattgac tgctgtggcg gtaggtgcag gtgctattgc gatctgtttg tttggttacc
    53701 atatcaataa tcagcggcaa catcagcaac ggatcaatta tgcagaatct gccatcacca
    53761 atcaaaaaga caccttgact tctttatcaa aagaagtaga caagctgtat agtacaaaag
    53821 aaaaaaattt tctaaaccct gaaataacag aagaaacaat cacaagtttg tcaaataagc
    53881 tatcctctgt caaactttca gcagatgatt acgacatcaa agaatcagaa ttgcctaaag
    53941 aagctgttgc aatccaagat gagaagaaag caatcgtgac acagttagat agtgcagaat
    54001 caaaactgaa gatccagaca gctgtcaacg atttatttac taaaaatgta tcaaactggc
    54061 agcaagctgt agacgatgtc gtcatcaaag aaaaggtgac aagtgcagat gtcgctcgtg
    54121 tacgtgaaaa tatgagcttt tttaaagata gtccttggaa aacgattgtt atgcaatatc
    54181 taggattcgc tgatactcag atcgcgcaag tcacgcaact agatcagtta ttcgatacga
    54241 tgttgaagga tggtcaagtg actgccaccg ctacttacga tcaatatttg acggtgctca
    54301 gtcaaataga tcagatccgg aatgaaaaaa tacgcgcagc atacgcaaca aaagcacaaa
    54361 ctgttgctca gcaaatgggc tatagcaata taagctattg acagttaaaa cgttgattca
    54421 agcaaggtta gcaaacggag gaaactatgg caagacgaag aagaaaatca agagggaaaa
    54481 aaatatttct gattatttta gcagttctta tcgtattagt attagcaatt gtaggagtag
    54541 gagcaaaatt atatctggat ctctcacatt ctattgagaa aacttacgaa tcagtggaac
    54601 gaacccaagg agaacgaacg aaaccagttg atctggacaa acaagaatct ttctctgttc
    54661 tattgatggg cattgatact ggagatttag gtcgggtcga tcaaggaaga tcagatacga
    54721 tgatggttgc cacagtcagt cctgaagaca aacagacaac gatcgtcagc attcctcgag
    54781 atacgtatgt cgacatcgta ggtcgtgaca caaaagacaa gatcaaccac gcttacgcat
    54841 tcggcggagc tgccatggcg atggataccg tacaaaaata tgtagacatc ccaatcgatc
    54901 actatgtctc tatcaacatg aaagggctaa aagaacttgt tgatgcagtt ggtggtatcg
    54961 aagtcaataa tgacctcact ttctcacaag atggctatga ctttacaatc ggtaaaatta
    55021 ctttgaacgg ggatcaggca ttatcttatt ctcgtatgcg ttatgaagat ccaaatggtg
    55081 actatggtag acaagagcgt caaagaaaga tcgtagaagg tgtagcgaaa aaagtattga
    55141 gtctaaacgg tgtcagcaac tatcaatccg ttttgaatgc tctagagtcg aatatgaaaa
    55201 cagacatgag ctttgatgaa atgaaaaaaa ttgctttaga ttatcgggag gcatttggta
    55261 cgatcaagca agatcagctg caaggagaag gcttcatgca agataatatc tcctatcaaa
    55321 aagtcagcga tcaagaactt gatcgtgtga aaaaagaatt aaaagatcaa atgaatctag
    55381 agaataaata ggaaagtgga gaaaaaatgg aagagacaat cagcttgaaa gaaatttttg
    55441 aaacattacg caaacacttg gtaacaatca tcatctcaat gtttgctggc ttggccatct
    55501 caggaatcgt aacatttttc atcttgacac caaaatacag ttcacaagca caattgatcg
    55561 tgacactgcc acaatcagac acagcaaatg tcaatgatgt caatacgaac ctgcaaatga
    55621 tcaatacgta taaagatatg atcgtcagtg atttagtgct aaatgaagtc aaagatcgtt
    55681 tagaaacaga agacaatgtg aaaatgactg ctgaacaaat caaagaggcc atctcagtca
    55741 atcagtcaca aaattcacaa atgttctcga tccaggcaat aagcacgaat gcagtgactg
    55801 ctcaacagat cgctaacaca acttcacaag ttttccaaga gaacgcaaaa gacgtgatga
    55861 atgtcgataa aatctcgatt atttcaggtg cagttgccaa tacgacacct gtttcgccaa
    55921 ataataaatt gaatttagtg attggcttag tattaggaat gatggtaggc gtaggtctgg
    55981 cattcttatt cgaattactc gatcggacag tgaaagatga aaaatatgtg acggatacat
    56041 taggattccc aatcttagga acagttccag aaatgtcagc gaaagaattg aacgctggta
    56101 tccgtaaaaa aggatcagct cctgcacgac caaaagctac aaatggtaaa acagcgccat
    56161 cacgcagaag ccgctcaaga gtctaggagg aagaaaaatg gcacgaacac agaaacaaaa
    56221 agcagcacaa actcatgcag tcagtttgat cacattaaca aacccatctt caccaatcgc
    56281 cgaacaatat cgtacgatcc ggacgaatat ccagtttgcc tccgcagctg gtcagcaaat
    56341 caaaacgatt gtcgtgactt catcaggtcc tggagaagga aaatccacca ctgcagcaaa
    56401 cattgcagtc gtttttgcta aatccggtca acgggttcta ttagtcgatg cagatttacg
    56461 taaacccgtc gtctataaaa cattccagtt gagcaatgct agtggattaa gtacagcact
    56521 tagttcatca ggaagtgtag cagatgtgat ccaacgaacg ccagtcgaga acttgtcgat
    56581 tttgcctagt gggcctaagc cacccaaccc atcagaattg ttaagctcgc caagaatgga
    56641 tcagattcta gccgaagcaa gacagatatt tgacgtggtg atattcgata tgccaccagt
    56701 agtagccgta acagatgcac agatcatgtc ttcaaaaacg gatggcactt tattggtcgt
    56761 acgtgaaaat acatcacgta aagaatcctt gtctaaagca aaagaactgc tagagatggt
    56821 acaagcacga gtcttaggtg ttgtatacaa cggagcagaa catagcaaag atgctggtta
    56881 ttactacgga aattaaggaa taagaagaga ggagacaaga gaaatgatcg atctacattg
    56941 ccatatccta ccaggaatcg atgacggggc agaaaactta gaagcaagta ttgcaatggc
    57001 tgaaaaagcg attcagcaag gcatcacgca tattttatgc acaccacacc acaataatgg
    57061 aaaatacagc aatgaaaaat cacaagtcat ttctctagtc gcttcgttac aagccgaatt
    57121 agagaaaaga caattgcctt tgacgttatt ggaaggacaa gaagtacgta ttaccggaac
    57181 gctcatcgaa gacatccacc gagatgaaat tttatttaca gatttagatg atacatatct
    57241 tctgatcgaa tttccgacac tggaagtgcc gttatatgca gaacggcttt tttttgagtt
    57301 gttagaacta ggaaagacac cagtgatcgt ccatccagaa cgtaacgcgc attttcgtaa
    57361 aaacccgaat tatttgcttc cgttcctaga tatggggtgt ttggcccaac ttactgcgcc
    57421 aagttatgtt ggggtgtttg gcaaagacat ccagaaaaca gctaaaacga tggtcaaaca
    57481 taatctcgtg cagatggctg cttctgatgc ccatggggtc tctaagcgca ccttttactt
    57541 aaaagagtgc tatgagcaga ttggcaagga ctttggtaag gaaaaagtag tacagatgaa
    57601 acaagtcgca aaggatctga tcaacgggga tgaaatcagt tatccagtct atgaagaggt
    57661 aaaaaagaag aaatttggtt tattttaggg ggaatgtagg gtgtttgtat taacaagaag
    57721 aagaaaaatt gccacattgg ttgttgtgga cagcttgtta ttaatcgctg caaatattgc
    57781 agcagctaaa ttcatgaagc cgtttgtagc tataccaatg gaccttattt taatctctat
    57841 tggtttgtcg attggttttt atttatttta tggtagttta tttaaagttt tcactcgaat
    57901 caatcgctat acaaatttaa gagagatcat tgcaattttt agttcactat ctgcaagtgc
    57961 tgcctcaagt atcctcatac tgctgttcat taatcggcga tacagtttac ggttagttat
    58021 ctttgcttat ctgctttcgc tcttattgat catcggtagc cgattgatct ggcgtatcta
    58081 catcgaaaca aaaaatatga gatatgtatc agcagattct gctaaaaata cattgattgt
    58141 tggtgctggc gaaggcgggc gtattttata caacagcttt cttggatcca aaacggctca
    58201 agatatccac gttgtcgggt tcgtagatga tgatccaaat aaaagaaata cgtatctttc
    58261 aggaaaaaaa gtattaggtg cattaaaaga tattccggaa ttgattgaaa aatatgacat
    58321 tcaaatggta acgatcgcta tcccttcctt atcaagaaaa aaattacgaa gaatcttcga
    58381 gttagtcgaa tccgctcgtg tgaaagtcaa cacgatgcct tctatagaag aacttgcttc
    58441 aggaaaaatt agcgtatcaa aattaaaaac aattgacgta gtggatttac tgggaagaga
    58501 tgaggtaaag ctggatattg aatccatcaa agatcagatc acagacaaag tcattcttgt
    58561 caccggcgca ggaggatcga tcggttcaga aatctgtcgg caaatcattc aattcaatcc
    58621 tgcaaagcta ttgcttttag gacatgggga gaactcgatc tacttgattg accgtgagtt
    58681 acgcacgcat catcaaaatt gtcctacaga aatcgtaccg atcatcgcag atatccaaga
    58741 tcgcgagaaa atcaatgaga tcatggaaca atatcatcca gatatcgtct accatgcagc
    58801 tgctcataag catgtaccac tgatggaata taatccaaaa gaagcagtca aaaacaatat
    58861 tttcggtaca aaaaatgtag cagaagcagc taaagcagca aaagtgaaaa acttcgtcat
    58921 ggtatcgaca gataaagcta acaatcctcc aaacgtcatg ggttcaacaa aacgaatcgc
    58981 tgaaatgatc gtgactggat tgaatgaaga aggctgtacg aaattctcag ctgtcagatt
    59041 tgggaatgtc cttggttctc gcggtagtgt gattccagta ttcagagaac aaattgctca
    59101 aggtggtcca atcactgtaa cagactttcg tatgacccga tacttcatga cgattcctga
    59161 agcgagtcgt ttagttattc aatctggcgc attagcaaaa ggtggcgaaa tttttattct
    59221 agatatgagt gaaccagtga agattgtaga cctagccaaa aacatgatcc gattgagcgg
    59281 gtatagcgaa gacgaaatcg aaatcattga aacaggtatc cgtccagggg aaaaactata
    59341 tgaagaacta ttgttggata aggaaagaaa tgatgaagca gtttatgaga aaatctttgt
    59401 aggaaacatc aaaggttact caatacaaaa agtgatggat tttgttaaga gcctgccaca
    59461 agacgatgaa caactggcta aagacattgt cacttttgca aatgcttcga atagatagga
    59521 gattaaaaat tgaatatttt aatattaagt tgtggacgtc gttgtgaact agtgaatgca
    59581 tttaaaacag cattaaacaa taatgaaatg gaaggaaaaa tcattggagc agattgctct
    59641 gaactagcac ccgcactata tatgtgtgac gaaaaaatag tattacctaa agtttcagaa
    59701 agtaattat
//
LOCUS       DAZKNV010000010        57174 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000010 DAZKNV010000000
VERSION     DAZKNV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.010"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..187)
                     /locus_tag="ACG8M1_000713"
     CDS             complement(59..187)
                     /locus_tag="ACG8M1_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFQ0421451.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG8M1_000714"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG8M1_000714"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFQ0421452.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACG8M1_000715"
     CDS             complement(1674..2729)
                     /locus_tag="ACG8M1_000715"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFQ0421453.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG8M1_000716"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG8M1_000716"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFQ0421454.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG8M1_000717"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG8M1_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFQ0421455.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG8M1_000718"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG8M1_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFQ0421456.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG8M1_000719"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG8M1_000719"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFQ0421457.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG8M1_000720"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG8M1_000720"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFQ0421458.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACG8M1_000721"
     CDS             10491..12050
                     /locus_tag="ACG8M1_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFQ0421459.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACG8M1_000722"
     CDS             complement(12161..14092)
                     /locus_tag="ACG8M1_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFQ0421460.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG8M1_000723"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG8M1_000723"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFQ0421461.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACG8M1_000724"
     CDS             complement(15021..15773)
                     /locus_tag="ACG8M1_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0421462.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACG8M1_000725"
     CDS             complement(15932..16141)
                     /locus_tag="ACG8M1_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421463.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACG8M1_000726"
     CDS             complement(16152..17480)
                     /locus_tag="ACG8M1_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421464.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACG8M1_000727"
     CDS             17616..17771
                     /locus_tag="ACG8M1_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFQ0421465.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG8M1_000728"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG8M1_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFQ0421466.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG8M1_000729"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG8M1_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFQ0421467.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG8M1_000730"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG8M1_000730"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFQ0421468.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACG8M1_000731"
     CDS             complement(21455..22387)
                     /locus_tag="ACG8M1_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421469.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACG8M1_000732"
     CDS             complement(22544..23203)
                     /locus_tag="ACG8M1_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFQ0421470.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG8M1_000733"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG8M1_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFQ0421471.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACG8M1_000734"
     CDS             complement(24244..24534)
                     /locus_tag="ACG8M1_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421472.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACG8M1_000735"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACG8M1_000735"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFQ0421473.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERYSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG8M1_000736"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG8M1_000736"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFQ0421474.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACG8M1_000737"
     CDS             complement(28200..29369)
                     /locus_tag="ACG8M1_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFQ0421475.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG8M1_000738"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG8M1_000738"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFQ0421476.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG8M1_000739"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG8M1_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFQ0421477.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACG8M1_000740"
     CDS             34320..34841
                     /locus_tag="ACG8M1_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFQ0421478.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACG8M1_000741"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACG8M1_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACG8M1_000742"
     CDS             complement(36284..36940)
                     /locus_tag="ACG8M1_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421479.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG8M1_000743"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG8M1_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFQ0421480.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG8M1_000744"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG8M1_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFQ0421481.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG8M1_000745"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG8M1_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFQ0421482.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACG8M1_000746"
     CDS             complement(40491..41222)
                     /locus_tag="ACG8M1_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFQ0421483.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACG8M1_000747"
     CDS             complement(41226..42491)
                     /locus_tag="ACG8M1_000747"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFQ0421484.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG8M1_000748"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG8M1_000748"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFQ0421485.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG8M1_000749"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG8M1_000749"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFQ0421486.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACG8M1_000750"
     CDS             47833..49335
                     /locus_tag="ACG8M1_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFQ0421487.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACG8M1_000751"
     CDS             49337..50074
                     /locus_tag="ACG8M1_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421488.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG8M1_000752"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG8M1_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFQ0421489.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG8M1_000753"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG8M1_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFQ0421490.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG8M1_000754"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG8M1_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFQ0421491.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG8M1_000755"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG8M1_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFQ0421492.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG8M1_000756"
     CDS             complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG8M1_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFQ0421493.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKYGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="ACG8M1_000757"
     CDS             complement(56756..56983)
                     /locus_tag="ACG8M1_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFQ0421494.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
BASE COUNT        15688 a        12462 c        10028 g        18996 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aatctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttattcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatacttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctc
//
LOCUS       DAZKNV010000011        56782 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000011 DAZKNV010000000
VERSION     DAZKNV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.011"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(105..629)
                     /locus_tag="ACG8M1_000758"
     CDS             complement(105..629)
                     /locus_tag="ACG8M1_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFQ0421495.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG8M1_000759"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG8M1_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFQ0421496.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG8M1_000760"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG8M1_000760"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFQ0421497.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="ACG8M1_000761"
     CDS             complement(2351..3031)
                     /locus_tag="ACG8M1_000761"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFQ0421498.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="ACG8M1_000762"
     CDS             3157..4026
                     /locus_tag="ACG8M1_000762"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0421499.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="ACG8M1_000763"
     CDS             4052..4567
                     /locus_tag="ACG8M1_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFQ0421500.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="ACG8M1_000764"
     CDS             complement(4614..5177)
                     /locus_tag="ACG8M1_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0421501.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="ACG8M1_000765"
     CDS             complement(5232..5411)
                     /locus_tag="ACG8M1_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421502.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="ACG8M1_000766"
     CDS             complement(5488..5997)
                     /locus_tag="ACG8M1_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421503.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="ACG8M1_000767"
     CDS             complement(6093..6473)
                     /locus_tag="ACG8M1_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0421504.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG8M1_000768"
     CDS             6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG8M1_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFQ0421505.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="ACG8M1_000769"
     CDS             complement(7736..9013)
                     /locus_tag="ACG8M1_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421506.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACG8M1_000770"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACG8M1_000770"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFQ0421507.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="ACG8M1_000771"
     CDS             complement(9935..10879)
                     /locus_tag="ACG8M1_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFQ0421508.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="ACG8M1_000772"
     CDS             complement(10881..11567)
                     /locus_tag="ACG8M1_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFQ0421509.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12041..12361
                     /locus_tag="ACG8M1_000773"
     CDS             12041..12361
                     /locus_tag="ACG8M1_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFQ0421510.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12515..13420
                     /locus_tag="ACG8M1_000774"
     CDS             12515..13420
                     /locus_tag="ACG8M1_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421511.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            13417..14190
                     /locus_tag="ACG8M1_000775"
     CDS             13417..14190
                     /locus_tag="ACG8M1_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0421512.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14371..15795)
                     /locus_tag="ACG8M1_000776"
     CDS             complement(14371..15795)
                     /locus_tag="ACG8M1_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFQ0421513.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            16006..16452
                     /gene="nrdI"
                     /locus_tag="ACG8M1_000777"
     CDS             16006..16452
                     /gene="nrdI"
                     /locus_tag="ACG8M1_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFQ0421514.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(16517..18499)
                     /locus_tag="ACG8M1_000778"
     CDS             complement(16517..18499)
                     /locus_tag="ACG8M1_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFQ0421515.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="ACG8M1_000779"
     CDS             complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="ACG8M1_000779"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFQ0421516.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(19412..20473)
                     /locus_tag="ACG8M1_000780"
     CDS             complement(19412..20473)
                     /locus_tag="ACG8M1_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFQ0421517.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(20684..21211)
                     /locus_tag="ACG8M1_000781"
     CDS             complement(20684..21211)
                     /locus_tag="ACG8M1_000781"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0421518.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(21278..22780)
                     /gene="eat(A)"
                     /locus_tag="ACG8M1_000782"
     CDS             complement(21278..22780)
                     /gene="eat(A)"
                     /locus_tag="ACG8M1_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFQ0421519.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(23038..24158)
                     /locus_tag="ACG8M1_000783"
                     /pseudo
     CDS             complement(23038..24158)
                     /locus_tag="ACG8M1_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            24284..25225
                     /locus_tag="ACG8M1_000784"
     CDS             24284..25225
                     /locus_tag="ACG8M1_000784"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFQ0421520.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(25375..26271)
                     /locus_tag="ACG8M1_000785"
     CDS             complement(25375..26271)
                     /locus_tag="ACG8M1_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFQ0421521.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            26540..27880
                     /locus_tag="ACG8M1_000786"
     CDS             26540..27880
                     /locus_tag="ACG8M1_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0421522.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            28098..28541
                     /locus_tag="ACG8M1_000787"
     CDS             28098..28541
                     /locus_tag="ACG8M1_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFQ0421523.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(29045..30463)
                     /gene="nhaC"
                     /locus_tag="ACG8M1_000788"
     CDS             complement(29045..30463)
                     /gene="nhaC"
                     /locus_tag="ACG8M1_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFQ0421524.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(30866..32089)
                     /locus_tag="ACG8M1_000789"
     CDS             complement(30866..32089)
                     /locus_tag="ACG8M1_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0421525.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(32120..32959)
                     /locus_tag="ACG8M1_000790"
     CDS             complement(32120..32959)
                     /locus_tag="ACG8M1_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0421526.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(32976..33656)
                     /locus_tag="ACG8M1_000791"
     CDS             complement(32976..33656)
                     /locus_tag="ACG8M1_000791"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFQ0421527.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(33658..34731)
                     /locus_tag="ACG8M1_000792"
     CDS             complement(33658..34731)
                     /locus_tag="ACG8M1_000792"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421528.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(34787..35025)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(35068..35301)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(35378..36049)
                     /locus_tag="ACG8M1_000793"
     CDS             complement(35378..36049)
                     /locus_tag="ACG8M1_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0421529.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(36136..38784)
                     /gene="mgtA"
                     /locus_tag="ACG8M1_000794"
     CDS             complement(36136..38784)
                     /gene="mgtA"
                     /locus_tag="ACG8M1_000794"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFQ0421530.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(39126..39300)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            39473..39910
                     /gene="ndk"
                     /locus_tag="ACG8M1_000795"
     CDS             39473..39910
                     /gene="ndk"
                     /locus_tag="ACG8M1_000795"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFQ0421531.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(39932..40798)
                     /locus_tag="ACG8M1_000796"
     CDS             complement(39932..40798)
                     /locus_tag="ACG8M1_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0421532.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(40958..43051)
                     /locus_tag="ACG8M1_000797"
     CDS             complement(40958..43051)
                     /locus_tag="ACG8M1_000797"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0421533.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(43800..44423)
                     /locus_tag="ACG8M1_000798"
     CDS             complement(43800..44423)
                     /locus_tag="ACG8M1_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421534.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHVGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(44582..45979)
                     /locus_tag="ACG8M1_000799"
     CDS             complement(44582..45979)
                     /locus_tag="ACG8M1_000799"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0421535.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(46011..46982)
                     /locus_tag="ACG8M1_000800"
     CDS             complement(46011..46982)
                     /locus_tag="ACG8M1_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0421536.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            47356..47781
                     /locus_tag="ACG8M1_000801"
     CDS             47356..47781
                     /locus_tag="ACG8M1_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421537.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(48269..48970)
                     /locus_tag="ACG8M1_000802"
     CDS             complement(48269..48970)
                     /locus_tag="ACG8M1_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0421538.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(48986..49426)
                     /locus_tag="ACG8M1_000803"
     CDS             complement(48986..49426)
                     /locus_tag="ACG8M1_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFQ0421539.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(49426..50001)
                     /locus_tag="ACG8M1_000804"
     CDS             complement(49426..50001)
                     /locus_tag="ACG8M1_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFQ0421540.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            50242..50451
                     /locus_tag="ACG8M1_000805"
     CDS             50242..50451
                     /locus_tag="ACG8M1_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFQ0421541.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(50849..51361)
                     /locus_tag="ACG8M1_000806"
                     /pseudo
     CDS             complement(50849..51361)
                     /locus_tag="ACG8M1_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(51487..52188)
                     /locus_tag="ACG8M1_000807"
     CDS             complement(51487..52188)
                     /locus_tag="ACG8M1_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0421542.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(52296..53739)
                     /locus_tag="ACG8M1_000808"
                     /pseudo
     CDS             complement(52296..53739)
                     /locus_tag="ACG8M1_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(53753..55618)
                     /locus_tag="ACG8M1_000809"
     CDS             complement(53753..55618)
                     /locus_tag="ACG8M1_000809"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0421543.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(55739..56590)
                     /gene="licT"
                     /locus_tag="ACG8M1_000810"
     CDS             complement(55739..56590)
                     /gene="licT"
                     /locus_tag="ACG8M1_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFQ0421544.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
BASE COUNT        16366 a        11971 c         9853 g        18592 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaag caaaacacat aaaaaatata gttgttttct
    11641 cacgaaatag acactatttt taaatatttt tcgttatttt tttatcacaa aaattatctt
    11701 acttattgta aggtaaagct ttttttaatt tattgcccga taatatatag aaataaggtc
    11761 tagttactgt tttttttaaa tgattaataa ataacaactt ctttctatga aattgcaaag
    11821 cattcatctt cttttccgct aacgatatat ccgtcagtgc ttggtacact ttactaaaaa
    11881 gtatgagatt gccgatatct ggataggtgt gctatactac agaaaaagat atacaatctg
    11941 ccaccgggta ggataaagag gatgatcatt ccattaggtc tttgaaggga tgattttcct
    12001 ctttttgtgt atttttttat agttaaggag gaatgtaagt atggcatgga tggaattaat
    12061 catagcagga attttggaag tattctggtc aacgatgatg aaatggagtg atggtttttc
    12121 taaaatcaat tattcttttt acacagtgat tggcatgatt gctagttttt actttttgtc
    12181 aaaggcaatc aaaagtttgc cgatgagtct ctcttatcct atctggacag ggattggcgc
    12241 agttggttcg gtcataattg gtgtggtctt gtttcatgat aagctgaatc tttccacttg
    12301 gttctttgtg gggatgctac tcatcagtat cattggcatc aagattacta gcggccacta
    12361 gacacttgga ataagtactg atcagaaaaa ataagccttt ttatttaata ttcaattttt
    12421 ttatgaaaaa ataagaaata agtccaatga cctagcgact tctccactca tcaggtgtat
    12481 gcttgtacta tctatagaaa aggagtgaat atttttgaaa agtctttcgg tccaagaatt
    12541 atccaagaac tttggtcaca aacaagccct cagcgatgtc agttttagct tatcccctgg
    12601 caaaatcgtt ggattagtag gtcctaatgg cgctggaaaa acaacgatca tgaaagctat
    12661 tttaggactg atccattact cagatggaac aatctgtatt ggtgaaaatg agatttctcc
    12721 ctctagtcat aaagggttgg aacaagtagg agcattgatc gaatacccgg gtatctatcc
    12781 attcttaaca ggctatgatc atctgaagtt attctctgaa accaacgatg tatctgctat
    12841 cgacactatc gtgaatcagc tcaagatgga aaagtacatt cacaaaaaag cgaaatccta
    12901 ctcgttggga atgaaacaaa aattgggaat tgctcttgcc ttactgaacc atccgtctat
    12961 cgttatttta gatgagccga tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa
    13021 aatcattacc gacttggcta ctcagggcac ctctttcttg atctccagtc acttactcag
    13081 cgagcttgaa aaaatggtcg atgagctgat cctgatcaat caaggaaaga tcatcaaaca
    13141 atgtacaatg gctgaattga accaaacagc gcaagatttc atcgttatct ctacaacaaa
    13201 tgatctagct gctcgaacga tcttgacaga agctggatat actttggaag atcctgataa
    13261 aatcaagctt ttaaaagaaa acgaagaatt attaggaacc gtgatccagc tattgtctgc
    13321 acaaaatatc catgtgacag acgtccagca tctgacgaat gatttggaat cttctctatt
    13381 ggaaattctg gattcagtaa agggggaaga agaaaaatga cattgcttgt aaaacaagaa
    13441 ttatttaaat tgatcaagaa aaagtcaact gctgttttat ctgttctatt agttgttttg
    13501 ctcataggaa cagcacttct agccaaaaaa tacacgacga tcattgatcc agttgaaatg
    13561 actgctcagc tttttagtgc cacatcttgg attgtcttta tcatgattgc agctgcaagc
    13621 acgatcattt cgatggaagc acaatatggt acattgaaaa atctccttta tcgaaagtat
    13681 tctcgaggag aaatattagt aagcaaatgg atcacattag ttatttattc tgtttattta
    13741 taccttttag ctattattgt cactgtgttg atgaaactga ttcttttccc ttcgatttcc
    13801 ttcacggaga aggtttctac tggtcaaaca ctgatccaaa gcttgttcac ttatactttg
    13861 ggtagttata tcggtttatg gctgatttta agtttagtgt tgatgattgc ttgctttatc
    13921 aatagttccg gcgcatccat ctcagcagga atcgtctttt attttgcttc gtcaatcata
    13981 tctggtatcc ttattgcact catccaaaaa tgggagtgga tcaaatggaa tccgatcagt
    14041 atgttgaatc tgcaaaacca aattggaaac gaagagatca tgaagcaatt gactcatctt
    14101 tctactaatc aaatgctatt cggtaattta gcttacatcg ttttgttctt agcattagga
    14161 tatctcgtat ttaagcgaaa aaatgtatga tgactcatca aaaaagaggc tgtgaaagag
    14221 acgttcagcc ttattgccga ttggctgtct cttaaacacc gtttattctg aaaaaggagc
    14281 tgtgacaaca tttgtgtcac agctcctttc ctagtatgtt tttgaataaa cgacaggctc
    14341 acaacctctc tttatacttc ttttatactt ctatacgtga agcatcccag tggcaaataa
    14401 aaccattgca atcactccga ccatcgtcac acctataagt aaaatcttat ctaagtggat
    14461 atgttgtaca ggctcgtttt gctccttacg tgctttgagg taaaaataaa tgcctggcaa
    14521 gaaaagaaca agaacaagca ttacttcatt aaaggctacg actagcatag cccatacttg
    14581 aaaggcactt gctaaaagcc ctactaaaaa ttggacccat tctttccgct gataagaaag
    14641 tttcatttgg tacaatccta agaaaagcca cgtgaagaaa atagctgctg taccaagtgt
    14701 gtaagcaaag ttataagcac tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca
    14761 taacgtcgtc aatacgatag cataagttgg tgccccattt ttgttgagtt ttccccatgc
    14821 tttaggcaaa agtccgtctt cagccatgtt tcccattgtt tcaatcggta agatcgtcca
    14881 tgagagccaa acaccaacta aagaaatgat caaaccgccg ttgatcacga ctgctcccca
    14941 tttaccaacc atcatttcaa acacatagcc catagcaggc tgcgccttga tcgtttgcag
    15001 ctgattcatc gtcattgtcc catatggaag catggaaacc aagacgtaaa taataatcaa
    15061 gccgaatatc cctagaatcg ttgctttccc aacatctgat tgtttttttg ctcgtgaacc
    15121 tacgacagag gctccttcaa taccaacaaa tacccaaagc atcaccatga tgcaactcaa
    15181 tacttgactg gaaaacggga tcggctgtcc attcgcattc aatataatgt cgctagaaaa
    15241 gttatcaatg aattgttgga tcgaaaacgt gctgatagct actacaataa ataaaaataa
    15301 tggcactaat ttacagaatg tgacgatagc attgacgaaa ctagcatttt cgactccccg
    15361 attcactagc catgcatatc cccataaaaa gactgtactc atcacgatcg atgccagatt
    15421 ttgcccacct tcaaatactg ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa
    15481 agctacgttg cctaaccagc atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa
    15541 acggccaaaa ccttcttctg cgtaactaaa gatcccgcct tttaaatctg gacgtttttt
    15601 attgatatta ttgatcgaca aggagagcat caacattgct gttcctacga gtacccaact
    15661 gaaaatagct gggccgccag ccgatccgga gatgtccgtc ataataccaa atacgccacc
    15721 tccaatcgct gaaccaatta ctaaggcagc aagtggaatt aaaccaattc cttttttctg
    15781 ttgctctgta tccatgtaag catcctccaa aataaaaccg cttttatcaa aaagtataac
    15841 aaaccttttt tatttttact taattaataa aaactttaat agaaatataa ttctaccggc
    15901 ttttttctca ttatacaagc aaagcgccta gtccctttcc aaattacacc accaaaaaac
    15961 ttaaaaaaga tgctatacta aaaggaaaga attggaggat gatccatgaa cattttatat
    16021 atatcgattt caggaaatac gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa
    16081 atgcatgcag aagatcctgt caatcctgaa gttactttaa aagaaatcca tgaaaatagt
    16141 gattttacga aagaaacaga accatttttt actttcgttc ctacttattt agacggcgga
    16201 aatggtttag ataacggtga tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa
    16261 catgaagaca atcataaact ttgtcttggt gtagtcggta gcggaaataa aaacttcaat
    16321 aatcagtatt gtctaacagc caaacaatat gcacaaacat ttggctttcc tttcttggca
    16381 gattatgaat tacggggaac accatctgat gtgacacgaa tttatcagat tttagcagaa
    16441 aacaataaat aataaaaaag aagaagctga aaaatagatt tcagtttctt ctttcgtttc
    16501 tattgtttct atcatattaa gctttgacat ccatcacagg tgcttttgct tttgctttac
    16561 ctgttttttc caagacaaag ttttttacac gatccatatt ggttaccaag acgatcatgg
    16621 atgtttcttt gcctgctgct ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag
    16681 gtgtcacttg ctgcccttct gttactttca catcaaatgg cgtaccgcct aagtcaactg
    16741 tgttgattcc catatgaagc aagatttcta aaccatttgg cgttgtgatc ccaatagcgt
    16801 gtttcgttgg gaagacagag ctgactaccc cagtaactgg agaatagata tgtccgtttt
    16861 ctggttctac aaagtagcct tcacccatca tcttttgtgc aaaaactgga tcacttgctt
    16921 tatctaaaga aacaactgtt ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg
    16981 aagtttgagg tactactttt tcaggcactt catttactgt ggctgtttca gtcgctaatt
    17041 cttctttttc taaacggtct ttaggaatac cgaagaagaa tgtagcaacg aagccaccag
    17101 cataagctgc caataatcca aggatgtagc ctaaccattt accgtcagag atcaatggga
    17161 tcaaagcggc tcctgaaggt ccaatagcga tagccccgac atttccgatc attccgatca
    17221 ctgccccgcc gatacctcca ccgatacaag cagtaataaa tgggcgtcct agaggtaatg
    17281 ttactccgta aatcaatggt tcgccgattc ctaggatccc gactggtaaa gctcctttga
    17341 tcatttctgt taattcttta tcttttttgc agcgaatcca taatgccaat gctgcaccca
    17401 cttgtcctgc accagccatc gcaagaattg gaagcaatag cgtacgacca gtttcatcaa
    17461 tcatttgcac atggattgga gtcaaaattt gatgcagtcc gaacataacc atcggcaaga
    17521 ataatgtgcc tagaacgaag ccggcaaatg ctccaccaac gccaagtacc cagttgatcc
    17581 caccgaccat gccatcagaa atgaaacctg ctaaaggcat gatgaagaaa atttcaatca
    17641 gaccgatggc aatcaatgaa agagttggtg taacgatgat atctaccgca tcaggtacta
    17701 ctttatgcag ttttttctca acgattgaca atagccaaac agcgaagatg acacctagga
    17761 tcccaccttg tccagctgca agagcttcac cagtaaataa gtttttcagt ggtgcttccg
    17821 gattcatccc tgtcagcatc acaacggccc cgataactcc accaagagtt ggtgttgcac
    17881 caaaaacttg tgcagcattg atacctgtat agataactag gtagctaaac atcccgtttt
    17941 tcaagatgtt catcacatcg atatattgtt gccatgttgc tgcatcaagt gttccggctg
    18001 tgactaagtt tgctaaaact gcggcaatcc ctgccacgat cccagtaccg acaaatgcag
    18061 gaatcattgg cacaaagata ttagaaatgt cttttaatac cgatttgatt ttagatggtt
    18121 tttgtttcga tttttgtgcc gctttcattt cttgtgcccg ttcgtttaca cggtcttttc
    18181 cagatgctga tgaatttgct gtagctgtac ttacagaaga aagtttttct cctaatttca
    18241 cgcctgccaa atcaaccatt tgctgtgcta ctttgttcac tttcccaggt ccgatgatga
    18301 cttgaagctg ttcatcttct actacaccaa gcactcctgg aatcgctttt aattcagaga
    18361 catttacaag atcatcattg atgatcttca tacgcacacg agtcatgcag tggacaatgc
    18421 tttctacatt gcccatgccg cctgcccctt tataaatttg ttttgccagt tcttccaaag
    18481 tcagttcgtt ttttgccatg gtcttttccc cctcataagg tcccttttac aaatccgttt
    18541 gcttcagcta attttgcttg agcttcctct ttatcactat ttgtcaaaat catgacgata
    18601 gccagcttaa cattttgatc tgcttcttca aagtactttt cagctgtttc gtaatcagct
    18661 tctgtcgctt gcatgatgat tcgttttgag cgttcgatta gtttttcatt tgttggtttg
    18721 acatcgacca tcaagttatt gaatacttta cctataccaa tcatactgat agtagaaatc
    18781 atattcaaga taagtttttg tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat
    18841 tctggacctg catcgacttc gattgggaaa tccgcgtgtt tactgatttc ggcttgttta
    18901 ttgcaagaaa tcgttcctgt gacagcaccg atcgattttg cgtaatctaa tccaccgatc
    18961 acatatggtg tacgaccgct agctgcgata ccaataacta tatcattttt tgtcaaattc
    19021 agcttgatta gatcttcttg ccctagctca taagaatctt cggccccttc gacagctaca
    19081 gtcattgctt cttctccacc agcaattaga cctatgacca tttccggttc tacaccgaat
    19141 gtcggtacgc attcagcagc atctaacaca cctagtcttc cacttgttcc ggctcccata
    19201 taaatcagac gtccaccttt tttaaaggac tcaatcgtgt tagcaatcac tggttcgata
    19261 cttgtcagtt ctttttcaac cgcagcggcc actttctgat cttctttgtt cattagttga
    19321 acggcttgag aaatactcat ctcatctaat ccaaaagttt cttggtttct gcgttccgtt
    19381 gttaggttct ctaaattgat tttgctcatt tttatcttcc ttcttttctt ataaattgat
    19441 agttcatacc agctttgatt tggttgatca atggtagctc ttctttgata actttagcta
    19501 ctacattcac tttttcatcc gctggcaaat catatttggt taattggatc tcacccatat
    19561 agcgcaaata cttttcgtta tctaaagtaa tagacccttt catacgcgta gctgtatttc
    19621 ttgctgggat aggcggaatc tctcgaaaac gtgcatctac gcttcgtatg acatctcttg
    19681 catcgtcttg ccgattcgta tgcttcccta atatatattc gtaaaattct tcatctacag
    19741 gttccgtatg gagcaagact gtctgttctt tttggaaaga agcaaattgc tcctgaacgt
    19801 tttctgacag acctgcatct ccgatgtaaa caatatccgt gttacttgct aatagatcta
    19861 gagcgcctgc aagaggatgg atccctcgat gttcttccaa agttggcaat ccttgatata
    19921 gtgggcctct caactctgta tctcctggta caaaaccttg gacaaggaga ccttgaattt
    19981 tgagccattg attttttttc tgataccatt ctttgtccag ccctgtttcg ggacgtggat
    20041 aataattatg ccaagcttca atctgtgaga aatcagcttc tgcttctttc aattcatcga
    20101 tatctttagg cgtgatcgtg ctagcattca aactgatttt caattgatgt gaccagtcgg
    20161 caatctgctg attggaaata tgataatcca ttcttaaacc tgttacacca attgctttca
    20221 aaggcgttag atcttctaat gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga
    20281 ccatcaattc tagtttattc tttttcgctt cgcttcctag ttcgatcaat cgcttttgat
    20341 atgccgaaac atcatcttct ggtatatgca tggaagtgaa aataccgaca aagccattgg
    20401 atgccatttg gcggatatac tgtttcttct cttctgacaa agaatcgttc ataaatattg
    20461 aaaagccaaa catattatcc ctctttttct gtatccgtct tcatttctat gactagagta
    20521 tatatctaaa gaaacaaaat ttcaatactt ttattaaaat aattaaattt catttctaaa
    20581 ggttgagttt atattatcaa aagaattgtc ataacctaaa aaaggcactg ctaagcaaaa
    20641 gcagtgcctt gaaatatttt atttaaataa cacaaaaaca taattactca taagaaacca
    20701 attctgtatt atctaccatg aatgtaaaga acccctcatt aggcatcgga tgaaaataag
    20761 cattgatcac tcttatcaag gcattatggc aaactaacag atagacattt tcttcgtctt
    20821 cgatgcattc tttcaataaa ggaacgatcc gtgcatacac atctaagact gactccccat
    20881 ttgggaatcg tacagcgaac gctaaacgtg ctttttgaaa gttctcatct ttgcttggca
    20941 gtccatcata atccccaaaa tccatttcta ccaatcgttc atcaacggtc agcggcaagc
    21001 tgagacgatc agcaactgct tgtgctgtat ctcttgctcg ttgaagaggg gaatggatga
    21061 ttttcgtgat tggaacaggc aaatctacta ccttttctgc tagtttctgt gcctgcatct
    21121 gtcctttttc agtcagcggc acatctgccc gtccgcaaac taatccttgt gcgttccaag
    21181 ttgtttctcc gtgtctcgtt acataaagca tgtgattctc tccttcgttg gcaaagttcc
    21241 ccttaaccat accttgttgt tcttgagatt acaagggtta gattctctca agagaaataa
    21301 tctcagtaga tactttatcc aggaaggttt gatcatgttc cactagtaac atggcaggtt
    21361 tcacgttcaa gatcagttgt tctaattgtt cttgattgaa gacatccaaa taattcaatg
    21421 gttcatccca tgtatatagt tcagctggct gtgataaaga tttagccaat tccacttttt
    21481 tccgttggcc catactcatc tgctcgatct tgttatgaaa aacatctctt tccatcccaa
    21541 gctttcggag gttgttcaaa aatgcttggt agtctacttg gtttttctct gcaaattccg
    21601 ccaacgttcc tcgattgtct tcataatttt ggcttgcata actaatgctc agatgttttg
    21661 gctggtattt ttctcctata accttgccgt tgaatgcccc cagaagataa tggataatgg
    21721 atgactttcc tgcaccgtta ggacctgaaa tcgccacccg ctgatgaggc tcgattgtaa
    21781 aatgaattgg ctcgaataac agattttcat accctaattg aagatcttct acgcttaaaa
    21841 gtcgcttatg gtgagacgct tggctattca tcgtcaaaga atcgatatat tcgatatctt
    21901 ttaatagttt ttctttctcg ctgatctggg tctccatccg attcacgatt gctttggatc
    21961 gtttcatcgt ccgtgcagca tcagcaccca ctgctccttt attcactcgt ctagattcag
    22021 tatcgatgaa tccgacttgt ttctttgttt tatctccttc tcgggaacga gaccattcgg
    22081 ctttttcagc tgctgttttc tttagcctac tgacttcttt tttcaatttt tcattttgag
    22141 ccatttcaaa ttcatcacga agttttttct gttcttcata gatagagaaa ttcccttgat
    22201 aaagttccag ttgacttttt tcgattgcta aaacatggtc cactacttca tcgataaatc
    22261 cccggtcatg gctgaccacg atgaagcctt gttttttctt tttcaaataa gccgctactt
    22321 gttttctacc agagatatcc aaatgattcg ttggttcatc gattaacggg aaatgagtgt
    22381 catccacaaa taaaagtgcc agtaggactt ttgtcttctc tccccccgat agtgtgctga
    22441 attctctcca taagatttca ggatctgttt gcatcaattg gagctctctt tcgatttccc
    22501 atatctcaaa atccgtaata tcatttaaca cgtaataggt taaacgttct ttatcttttg
    22561 tctgttgcgg gaaataggca aattcttgct gatggattac ttgcccttga taaggtagtt
    22621 tgttttgtag aatattcagt aaagttgtct ttcctcgacc gtttcgtccg ataagtccta
    22681 gtttccattg tgtgtcaaaa tttagatttg cttgttcaaa taataatgtg ccttggctgt
    22741 cgtagccgaa tgtcagattt tttatttcga ttttagacat tttccatcac ctcgtaaaaa
    22801 aagaccagtc ctattttcag aactggctaa agaggatgca agggttggat acacacaaaa
    22861 agacccatac atcgaaaaaa ccaagccaat cccgaaaatc tgcacactgc ttccttgtct
    22921 ccacaaggta cagtctgaat gcagctttca tcaatcgact taatttttca atgcacggat
    22981 ccctcacttt gtcctatatt tgaaattacg atagcataaa gaaaatgatt ttgtcaacta
    23041 cttcgggagg atggtgaaaa atctgctaag tgtctgtcct aagatttttg ttttttctaa
    23101 tgtttgcctg tgttccattg cttcttctaa acctattgga cccaaatgaa tacttaagac
    23161 aattgggaga aaatcagaaa gtccttctag ctcttggtct ctacttccgc aaatagcgat
    23221 tattggtttt cgatattttt ttgcaagcac tgctacaccg tatggaactt ttccgtggat
    23281 cgtttgctga tcgatccgcc cttctcctgt aatgatgaca tctgcttgtt cgatcttttt
    23341 ttccaatcca gtgatttggc tgactaaatc gaaaccagaa accatcttcg ctcccaacaa
    23401 aaaagggctc caccaatacc gcctgctgct ccacttcctg gaatatcatc taaatccacc
    23461 tcccagaaat cttttatttg ctgagcaatc tttcctgctt gtttatctaa gaaagctagc
    23521 gtcgtatcta ttcctccttt ttgtcttcca aattgccaag cagctccttg ttgacctgta
    23581 tatggattgg taacatctgc agcgataatc aattttactt tagaaacaag aacgtttctt
    23641 cgatcaaaat gaagtttttt agtagataat aaaggatttc cttctgtgta cccttctaaa
    23701 gaagcaccca aggattggag taatcctaga ccaccatcgc tacacccgct tcctcctaaa
    23761 gtgacaataa tttgttctac ttcttgaagc agtgcatctt taataagttc tcctaaggca
    23821 taactggaag caagtcggat agtttgatcc gttggtttat caagtagatc taaccccaat
    23881 gcttgtgcag attcgatgac tgcggtgttt tttccttgcc aagttgtcaa taaatagctg
    23941 atttttcgct gacggaataa gagatccatc ccatcaatgg tacgccatgt tcccctgagc
    24001 gcgtaataga ttgcttctgc agtattttct ccgccatctg caatcggcac attgattttt
    24061 cttcctttac gatcttccca gccatttaga actgcctgat ttagttcaaa tgaagaagca
    24121 cttcctttaa atgaatcaat tgccgccaaa atatccatct gtatccctca ctttcttctt
    24181 aagtaagaca ctttttttca tttttttcaa acaaaacaat gctattttct tccatttttc
    24241 tatatactaa aagggaactc attgaataaa ggagagaaaa aacatgaaaa tcgcaatagc
    24301 tggggccgga gcaatgggca gccgaatcgg attgatgcta catcaaagcg gaaatgaggt
    24361 cctcttgatc gatcgttggc ctgctcacat tgaagccatt cgtacaaatg ggttgattgc
    24421 tgactttaac ggtaaagaag tggtcgcaaa actgccaatc tattcaccag aagaaatcat
    24481 cgaaagcaac gaacacgtgg acttgatcgt agcattaaca aaagccaatc aattagatga
    24541 tatgttttgt tcgatccaat ccattattac tgacaatact tatgttttgt gtttactaaa
    24601 tggattaggt catgaagatg tactggaaaa atatgtgcca aagaaaaata tcttatttgg
    24661 gatcacgatg tggacagctg gtctagctgg tcccggaaaa gtcacattgt taggtgatgg
    24721 agaaatcgaa ctagagaact tggaaccaga aggcgaagca tttacaaaaa aagttgtaga
    24781 agtctttcaa gaagcaaatt taaatccgat ctatagccat aacgttcgtt attccatttg
    24841 gcgaaaagct tgtgtaaatg gaacattgaa tggtttatgc acgattttgg attgtaatat
    24901 tgctgaacta ggcgcgcaaa aagcggcaga gagcatggtt cgaacaatcg tatctgaatt
    24961 tgcttctatc gcagcaaaag aaggaatcat actagatcaa gaagaagtgt accaacatat
    25021 tgcttctact tatgatcctg acaacatcgg gttgcattac ccatctatgt accaagacct
    25081 gatcaaaaac catcgtttga ctgaaatcga ctacatcaat ggtgccattt ggcgaaaagg
    25141 acaaaaatat gatattgcta caccatattg tgcctttttg acccaattag tccatgcaaa
    25201 agaaggaatc cttggcgcag aataaaaggc tctctgatga gaatcagctg aatcagcagc
    25261 tggttctctt tttttaagcc caataaaaga tcaaaaagaa aacacaactc tcatgatgcc
    25321 ataagaattg tgcttgtttg tttcagtaca taatctcttc aaaatgtagg ttttttattt
    25381 gttttcaaca gaggagaggt catattcgta ttgctcataa atagtggaat cgttagtgat
    25441 aaatcgtttt gcccaatttt ctgcatcata aaattccaat agctctgata ggattggctt
    25501 aaatggtgta tgcagaaatt ccggtaattc atctaaatca cgttctcgaa gcaaaaaaat
    25561 attttcagga cgataaaaat gataatgagc aatcgcttga ttatccgtca ctagtttctt
    25621 ttgaaaatac atggattcaa atgtccgcaa agtcactcct tgctgaccct cccgcaacag
    25681 ttccagaatc ccgcgcgatt cccctgtttt tttcaggtac tcttcataag taagatatcc
    25741 aggttgttca ttccctcgat gtggaagaat gaaatagttg gtcgtaacat ctctttttat
    25801 aaattcctgc ttatagcttt ctgctcgttc ttttctccca ttattcgttg caccaaaaaa
    25861 tagatccgtc tttggttcgc tagaagaaaa attcatatgt ttcgaataaa atgaactatt
    25921 atgtttcagc ccaagttctt ttgcttccaa aaaatcaaaa tgataaatct catcgattgc
    25981 cggttcatct tgtgcctgct tcagcatcgc ctcgtgttct gctttgaagt gattccaaaa
    26041 aaataacaca atttttgcat tggtaaatgg gcgcacgcgt cgagccatct ccatatcaaa
    26101 tccataatct aaaaaaacga tcagctgata atttgccaac tgttgtctag ctgatttaat
    26161 gaattccgac tgtagtaaat cttttccgga ccaaacatct aaagagcgga tggaaggcaa
    26221 aaaataaagt gatttatttt ttgcaactag cagtacgtca tttttgttca tcttttccgc
    26281 ctcactttct ctgtcacttt ttcctatgat agcctgttta aatagtaaaa agccagtaaa
    26341 acgtttccta tatttgtatg aaaatttaac atttgtatga aaatatgatg aaataaatca
    26401 ttcttctatt aaaattcgcc taaaagtttt ctgaatagtt gtaattgtct gaaaatttgt
    26461 tatcattagt cattgttaaa tattgctatt tattcttaat ataaattttg attgtgaatt
    26521 taaaagaaag aggtcattta tggaagataa aaaattgaaa aaacaactta gctccagaca
    26581 tatcaccatg ttagctttag gtggagcaat cggtgcaggt ctatttaaag gaagtggcga
    26641 agcgattggg atcgccggcc cttctgtatt gattgctttt ttgattggtg ggctgatttt
    26701 atatatcgtg atgaaaggtc tgggaaaaat cgttttaagc ggtggcgaca cgcatcacgg
    26761 attatctggt ttgatacgcc cttatctagg tgctcattct gctgatttta ctgattgggt
    26821 ctactggtct atgtggatta tcaatatcat cgctgaagct gttgcagctg cttccttttt
    26881 gcagttgtgg ttcccgcaca ttccagcctg ggtatttgtt tttatgttgg ctgttttaac
    26941 tacgatcatc aatctttatt cggtacggtt attcgcagaa acagaatatt ggctggcttt
    27001 tgctaaaatc agtgtcatta tcttactgat catttttgct acttatcttg tcggtcagca
    27061 aatgttgggc acaggcgttt tccctaccct tcagcaattg actgaccatg gtgggtttac
    27121 tcctcatggt atgaagggaa tcatcagttc tttgcttgta gttatctatt cttacggcgg
    27181 ttctgaactg attgctatca cggtaagcga agcagatgat cctaaacgtg cgattcctaa
    27241 agcaatcaaa ggtgtcatgg gaagaatcat ttccttttac atcattcctt tgtttttgct
    27301 tttgattctt tttccttgga atactttagc aggcacgaat gtcagtcctt ttgtgatggt
    27361 atttgaaaaa atgaatatcc catttgcagc ggatatcgtc aattttgtga ttgtccttgc
    27421 tttgttctca tctatcaatt cgggtgtgta tgcatcttca agaattttgt tcttccgttt
    27481 gaaggatcga aaaggttcct ctagaaaact agctgtttta aacaagcatc aagtaccgca
    27541 acgtgctgtt ttattttgta ccagtgttct ttatcttggt gtagctcttt cttattttgt
    27601 cggtgacaaa ttatttggct atctggcagg ttccctttcg tatacagtat tattgatctg
    27661 gatcattatc agtgcggcat cctttgtact ggcactaaga aaaggaacat tatgggataa
    27721 aggaatcagc ttttttgcat tagctgtctt aggattgatt ttccttggta tcctgttcac
    27781 gaactccatt ggggtaactg tattgactgg cctgctttac ctgttcattt atttcagtta
    27841 tcaaaaaaag aatgatgcgt tcgtattgac gaatgaatga aatcgataga aaattttatt
    27901 ttatttatgt ggaatagatg gagctattga agaaaggagt tgtgacaaaa gtcttgttgc
    27961 aactcctttt tccgaataaa cagtctcatg acctcttggt aaacggtgtt caaaaaccct
    28021 ctgtgcaaaa taattgattg ttctccatgc tcatgacatg atagaagaaa ggaatgaaaa
    28081 aaaggagttt gttttaaatg aaaaagtatt ggaagttttt gttgatgatc ggtgtttcaa
    28141 cggtagttat gtttggtatg atgtacttga atgtctatgc gctcgatcat atcttcttca
    28201 gtcgtacacg agtattcatg gcgttgatga tgggtgcagt catggcagtc atcatgctgt
    28261 tgttcatgtg gaaaatgtat gaaaacaaaa agataaatgt tatgatctta gccgctagtc
    28321 ttcttgtttt tgccggttcc ttgtttatgg tacgaagcca aactactgtc aacgacacag
    28381 cttggatgaa ggccatgatt cctcatcatt ctatcgctat cctggcaagt aaacgagctg
    28441 atttaaaaga tcctgaagta aaaaaattag cggaagaaat cattcaggca caagaagaag
    28501 agatcgacaa aatgaaaaaa atgatcaaag aaatggaatg accattatcc gtccaaataa
    28561 aaaaagagga tgttccagaa gttatcagct tcaagaaata agaagaagct acttctggaa
    28621 cgccgtgaat aaggggttgt gaaaaagctg ccctgcatca agtaataaga acagccaaac
    28681 aaaaatagct tctcctattt ttcgtttggt taggcttatt accgcagatg caagcttttg
    28741 aacaccgttt attaagaggt tgtaaaatca gcgttctgac ctgagtatta gagagacaaa
    28801 tggaaaaata gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt
    28861 gaacaccgtt tatcgagagg ttgtgaaaaa gtcgcttagt ttcgcgtatt aagaaaaatt
    28921 ttgtgaaatg gctttccaca tttttgtata aatttggctt aataccgaga aactggcttt
    28981 tgaataccgt ttattcgtaa aagggattgt gacaaaagtc ttgtcacaat ccctttttat
    29041 gtttttattg ttctaattgc gctgtcttgc ttactgcttc ttgcggtttc acaaattttt
    29101 ttgagattcc ccaacctgtg aaggcactga ccatcgaaaa cacaggagaa agcaaactga
    29161 aaaatacgaa tggcaagtaa gtgagtgtag gaataccaaa tgtacttgct acgaaacttc
    29221 cggcaattcc ccaaggcact aagtagttga ttactgttcc accatcttct agcgttctac
    29281 ctaatacagt tggatcaaat cctgcttttt cataagtttc tttaaatgca ttaccaggca
    29341 gaataacaga taggaattgt tcaccaataa aaatatttac tccgatactt gtcatcaatg
    29401 ttgtaaaaat caaatttggt gtgttcgtca tctttcttga tactcgttcc atcacggttg
    29461 agatcaagcc aaattcgatc aacaatccac ctaatgacaa agttagaata atcaatgaca
    29521 cagtaggcat catactttcg attcctccgc ggctaagcag tgaatcgatt tgttggtttc
    29581 cagtatttga aacaaaccct gattcgatga ccccagccaa cttcgttaag gaagtttgtg
    29641 ggttttgaat aaaaatcatt cctactgcta cagcgatatt caacaaaatc gttaaaattg
    29701 ccggcacctt tttccatgca cacagtaaca ttaaaaataa aggaatcagt gaccagattg
    29761 aaatagtaaa gtttgcttct agaacatcag tcacttcacg aatagatgaa agacttgcgg
    29821 ctttacttgt gtgtcctaaa atcatgaata aaaagaaaga aacaacaaat gccgggacag
    29881 ttgaccacat catatgcttg atgtgtttga acaaatcggc atcaacaata gctgctgcta
    29941 gatttgttga ttcggataat ggagacatct tatctccaaa aacggcacct gaaacaatag
    30001 ctccaacaac cagcgctgga tttaagccta gtgttgtccc aataccgaaa aatgcaatcc
    30061 caatcgttga cataacagta aaggcactcc ctacagcgct acctacgatt gcacacacaa
    30121 caaatacaga agggacaaac cactggacac tgatcaattt gaacccaatg accattagag
    30181 ttggaatgat ccctgcttgt atccatacag caatcaatga accgactaaa ataaaaataa
    30241 agattgggat gattcctggt ttgatgccat tgatgattcc ttcgtgcagc caatctgtcg
    30301 ggtatctttt tatcactgca tacaacatga ccattccgat cgctgctaag atcgtgatat
    30361 taggtgagac ctttaatccg acaacgccaa tcgcaatgcc taaaacaata accattaata
    30421 caagtgttgc ttctaaaaaa cttggtgttc ctttttttcc catgataatc tctccttttt
    30481 tagttgttct tatgttctaa aaaagttaag atatcggatt actccgccgc aattcatccg
    30541 cgattcctcc tttataaaaa taaaaagacc tgttttaaac taaggacgaa tgactccgcg
    30601 gtaccacctt aattaaaaac agatctgttt ttcactttca aacttttatt caaatgtatg
    30661 gactttccat gtaattcgtc aattaggctt gatcggttca cagcgaccac cgactttctg
    30721 aacaaaacac ctaaccgcta ctgcgtgaaa agttgacttg tacgaagttt accttccata
    30781 agatcatttg tcaatgaaaa agaaaatatt ttttcatttt tctgaaaatt atttttataa
    30841 ctttcacaca caagtttatt ttttactaga aagtagcgcc ctcttgtttt tttcttgcta
    30901 ctatttcttg atgttcttgc ttgattcttt ctaatagctt tggctctttc aacagatcaa
    30961 gagctgtatt ggcgagtagt tctgctgcaa tcgcaataga agcaaggcct ttgtcacttt
    31021 tagcagcagc tttgaattct tctgtgtgtc cggcaatata tgtctcagag attgctaccg
    31081 taggctggat tgttggtatg acttggctga catttcctac atcagaagaa ccgagacttg
    31141 ttctttgttc cgtttctatt tcttcatctg gaacacctgc ttcttttgca tgctggaaga
    31201 ataagtcatc aaaagaagga gtaacgatga catcatcaac tgcattttgg aacaatccaa
    31261 actcaaaagt cgtgcccgta cttatcgcag cacctcgtac gatattttcc actttttcat
    31321 atactttatc taatgtttgc cgatttcctg cacgtaaata gaaacgtcca gcagcgtaat
    31381 ctggaatgac gttggcagct actcctccgt ctgtaatgat cccatggata ttgacatctt
    31441 ttggcaattg caagcgtaga gcgttgattc cattaaacac ttggatcaat gcttccaaag
    31501 catttactcc tttttcaggt gctgctgctg catgggaagc gacaccgtaa aatttgatgt
    31561 cgactggatc attcgctaaa gattctgtcg ttttcccata acgaaaagct ggatggacgc
    31621 ataacgctac atcgacatcc tcaaaaaaac cttctcgaac aaagctgcct ttagctgatc
    31681 cgttctcgcc cccttcttcc cctggggtgc catatacacg gatttctcca ccagtttcat
    31741 caatgaattg cttcactatg ctggcggcta atacggagta agtaccaaac aaattatgcc
    31801 cgcatgcatg accaatacct ggtaaagcat cgaattctgc caaaaaggca attgtgggac
    31861 cgggtttatt ggaaatataa cgtgcatcaa aggctgttcg gtgtccagct acttcttttt
    31921 ctacccaaaa cctttctttt tctaattgtt taatcaacgc tgctgaggaa taaaactcat
    31981 agttacttac ttcaggatgt tcgtggatat ctagagcaag tgcttgatat tctggtaaac
    32041 gatattggat tagatccttc aattggtttg ttgagattgt tgttgtcata aaaaattcct
    32101 cctatgctag tcatttttct tattttctcc cgaatgtttc ccatgcaggc acgcttgatc
    32161 cttttgatgt tttctcgatt actttgactg tgtcttctgt ttgataagcg tctactattt
    32221 tttgatacgt tttattgttt tcatcttctt ttcttgcaac gatgatattc acataaggac
    32281 gtgcatggtc atccactggt tctaagaaga tggcatcaga agcaggatta aatccagcat
    32341 ctacagctac accgctattg atcactgaaa tgtctacatc tgacaaagca cgtgctgttt
    32401 gggaagcatc taattcagaa atgtctagat tttttctatt ctcggtaata tcagaaacag
    32461 tgggcgcttg tccttttgcc ttatccactt tgatcaatcc agcagtttgc aataacagaa
    32521 gagctctgcc gccatttgta acatcattag ggattgctac ttttgctccg tctttgatat
    32581 cagctacatc cttcaaagtg ttagaataaa ttcccagcgg tgcattgaca gtatttccga
    32641 tcgatactaa atcagttccg tgttctttat tgtaattgtc taaaaagaat tgatgttgga
    32701 aagaattcaa atcaatcgat ccatctgcta aagccacatt tggttgattg taatctgtaa
    32761 atttcacgta ttccaaatta atgttctcct ttttcaaacg gtctttcacg ttgtcccata
    32821 catctgtatc ttctccaata atccctagtt ttacgatagt ttcttttttg tcagttgtat
    32881 ctgcttttcc ttggctacac cctgccaacc aaataattgc tacaaatgta atgactacaa
    32941 aacgaataat ttttttcatt ttttctcctc cactttcaat gtgtaatttt tttaatcagt
    33001 tgattactga taaattgact taaaaaaact aagattagaa tcaataatgt agccacaatc
    33061 gttacatctg tttggaatcg attataccct ctcgatatag caagattccc taatccgcct
    33121 gcacctactg ctccagccat ggtagtcagt ccgatcacgt tgatgatagt caacgccgag
    33181 acccgaatga taccaggcaa accttctaac aaatacacac gtaaaatgat accgattgga
    33241 ctggttccca tcgcttctgc cgcttcgatc accccaggat caacttctag cagtgcgttc
    33301 tcgatttgac gagcaaaaaa cggaacaact ccaaaaatca atggcactaa agctgctttc
    33361 gcaccaatcg tcgttccaac taagaaacga gtagtcaatg ctaaaagaga aagcaagata
    33421 atgaaaggga tggaacgaat gatattgatc agcttatcaa gtatttcaaa tagcagacgg
    33481 ttagctagta atccattagg gcgtgtcact actaacgtca cacctaagat gattccaatc
    33541 atcccgccaa tgaatgctgt ccaaaaagac atatatagtg tttgcttcgt cgcttcgaca
    33601 aattcatccg gaatcaaata aacattgggc aaatatgttt taaagaaatc agtcatttta
    33661 tcttcctcct tcgatcactt tgatacgact atctaaatcg tttttttgta aaatatttat
    33721 ttttacacca gatttgatca aataatccaa tgcttttttc cgctgtttgg tttctccagc
    33781 taaagtaacg atcaaactcc ctaacggcgt ttcttgtaat aactctacat tgccatataa
    33841 aatattcgct gttacttgat atttgctgta cagatgagcg attagaggtt cgttcgtctg
    33901 atttccaata taacttaatt ccaccagcca tttattggcg atctgatcgg caaaagcaga
    33961 atgggcaatg atcgtttcta atgcttggtc aagatgagta gctgttcgaa taaaatcttt
    34021 ggtcaattct tcttcaggat tgctgaagat ctggatgctg ctaccttttt caacgattct
    34081 tccatcttcc ataaccgcta ccttgttgca gatttctttg acaacttgca tctcatgagt
    34141 gatcaggacg attgttaaac ctaactggcg attcaatttt tttaacaatg caaggatctg
    34201 aagggtcgtt ttcggatcaa gtgcactggt tgcttcatca cataataata ccttaggttc
    34261 attcgccaaa gctcgtgcga ttgctactcg ttgtttttgt ccccccgaca gttgtttagg
    34321 ataagcagat gctttttctt ccaaaccgac aagttccagt agttcattca ctttttgacg
    34381 acgttcctgt ttcgattttc cagaatactt taaagaaaaa tcaacgttgt caaaaatagt
    34441 tcggctttcc attagattga aatgctgaaa gatcataccg atggcctttc tttcttttcg
    34501 caattctttg ggagagagct gactcagatt cgtctgattg acaatgactt ctcctgctgt
    34561 tggtttctgc agcaaattca tcacacgaac taacgtactt ttccctgcac ctgagtaacc
    34621 gacgattcca taaacatcgc ctttttcaat cgttaaatct acagaatcta ctgcctgtat
    34681 ctctttttct ttttgtttga aacatacaga aacatctcgc aattcaatca ttaaaattcc
    34741 tccttatcta aaaaaagcgt cctcaagaaa atgaaaatgt cattttcttg aggacgcttt
    34801 tttgcgtgtt accacctcat gttcaagctg tgttcacaca caactcctct tcaagtacga
    34861 tcatactcta gcaagatatc ggtcgcagcc gtcatcgcct tacatctatg ctcgggatga
    34921 attgctcgat ggccattttc caatagtcgt tccttgcttc ttctcagcta ccgaagctct
    34981 ctgtcaaagg ttcttctatc gtacttacca tttcaatgca aataatattc aaaaaaaaag
    35041 tccttttact aacataaact atgtcagtaa aaggacgacg tatcgcggta ccaccttttt
    35101 tcggaagttt ccttccctca agcccaacat ctcaaaaaga gagattggcg ttcgttttaa
    35161 cggtcgaaca gttccgaatt tgcctactta tcgacaaatt attctccaag gccattttca
    35221 gcttttctta cttgactctt ctcaccagcc agagcctctc tgcaaagttt ccaaacttac
    35281 tttccttttc aacgaaatcg atattttgtt gttgggatta atctacatga ggaaaactga
    35341 aaagtcaagt acgaaattca aattattttt tctatattta tttttctgtt tttttattta
    35401 acatttcaat aacagttcga agatcttttc cttccgcaag aagtttcaat ttttcctttt
    35461 cttcgacggt ataatttcgg acaaaactgg aatcaggtat caaaacaacg cctaatcctg
    35521 ctcgtgaagc agctgttgct cctactaaag aatcttccac tgcaaaggct gaactagctt
    35581 ctaatcctgt tcgttccaaa gctgtcagat aaggaatcgg tgaaggcttg ttctccgaca
    35641 cttcgtctcc gaatgtaaac gtgtccaagt aatcagctaa tttaaagtga tccaagatat
    35701 ctgttgctct tttcgtaaca gtggtcgtag caatgcctag tttcatatga cgttctttta
    35761 agtctgccaa tatttctttt gcatatggtt ttaagtggat ggctccgctt gtcagctgtt
    35821 gataaaaata ttcttcacgc ttcgctcgga cttcctgtac tttttcaggg ctacctgctg
    35881 ctttcactaa aatatcaaaa ctttgtttcc agttttttcc gccccaagcg tcaacgattt
    35941 cttttgggat atggatatca aattgctgaa atccccaaag ccagccatca cgatacgttt
    36001 tttctgtgtc aactaacaaa ccatctaaat caaatattgc acctttcatc tatacattaa
    36061 tcctttccaa aacaatacac atagtttagc acgactggtc caaaaagaac agaagcaaag
    36121 aaccagcctt ctcgtttata agagttcttg gaatcgacgg atatagattt tcttcacagc
    36181 tgtcacaagc gccagataag cgatgactgt agcaaataac cataaccagt aattgccagg
    36241 aagtggcatc aagcctaatt cagcaccaaa acttgtaaaa ggaaggacag aaccgacaat
    36301 aattcctaat gtagtgataa caaacatggc aaatgttgcg ttgctttgga taaatggtac
    36361 tttcggtgta cgcagtgcat ggagcactaa ggtttgtgtc catagtgatt cgacaaacca
    36421 tcctgcatgg aataatgcga tgaaaatcac tcgctgtgaa ctatccaatg tatggaaact
    36481 tccgcccact acagcaggac aaataacaaa atacatcaac aagtaagtag taatatcaaa
    36541 tatcgaactt gttggaccaa agtaaaccat gaattcccca atactagatg cattccattt
    36601 ttttggctcg tccaaatatt ctttatccat ccgatcccat ggcaaggaaa tgcaggaaac
    36661 atcatagatc agattcaaaa acaaaagttg taaaggcagc attggtaaaa atggcaggaa
    36721 cgtacttgca atcagcacgg aaaacatatt gccaaaatta gaacttgctg tagccttgat
    36781 atatttcatg atattcccaa aagtttctcg tccagaaaga aggcctcttt ccaaaatcgt
    36841 caaatctttt tctaaaagga tcacgtctgc agattctttc gcaatatcca cagctgtatc
    36901 tacagaaata ccgatatcag ccactttcat tgcaggagcg tcattgatac catctcctaa
    36961 aaatccgaca gtatgaccat ttttacgtaa agctgtcgtc aaacgtgctt tttgctgagg
    37021 attcaatttt acgaatactt catggtcttc agctacttgt gctaattcat gatcactcat
    37081 ttccgagatt ttctcaccgg taaccaattc attgatctct agacctactt gacggcacac
    37141 tgaacgtgta actaattcgt tgtccccagt cagaactttt acagctacac catgttcttt
    37201 cagagctttc aacgcttgtt tcgttgtttc ttttggtgga tcaaggaaag caagataacc
    37261 aatcaaaacc atgtctgact catctttgac tgaaaattct ccaacgacgc ttggattggt
    37321 cttttgtgcg acaccaatca ctcgtaagcc atcttcatta agtgactgta cttttgcaag
    37381 tacggcttct tttcgttctt ttgttaatgg tgtaacagta ccgccaagat caataaattt
    37441 agaaatgttc agcatttctt caatcgcgcc ttttgtgatc atttgtgttt taccagctgg
    37501 atcagcaacc acaacactca tacgacgacg ttcaaaatca aaaggaattt catccacttt
    37561 ttgataattg atcttatctg tatctaaagt ttctgttgct tcatcaatga tagccacatc
    37621 taacaaattt ttcagccctg tttgatagta gctatttaga tacgcatggc gcaaaacacg
    37681 atcatcttca tttccttcac aatccatatg atattcaaga atgattttat cttgtgtcaa
    37741 tgtccccgtt ttatccgtac ataacacatc gattgcacca aagttctgga tggcattcaa
    37801 atttttgatc actgttcctt ttttggccat cacacttgct cctttgacca aattcgtcgt
    37861 aacgatcatt ggaagcattt caggtgttag accaactgct acagatagtc caaaaagaaa
    37921 agcttctagc caatcccctt ttgtaagccc attgatgacg ataactgctg gagccatcaa
    37981 tgacataaat ttgatcagta gcatggatgt tttatggatg cctaattcaa agcttgattg
    38041 aattggtttt tcagatagcg tttctgctac atgaccaaat agtgtttcat ttccaacaga
    38101 aacaatgatt ccttccgcac ttccactgat gacattactt cccataaaga caagattttc
    38161 gtaacttgtt tcgctttgct gatcgtcttc acatactttc gcatgctttt ctactggata
    38221 gctttcccct gtcaatgctg cttgggaaat gaataaatcc tttgcggaca ataaacgcat
    38281 atccgctggt atcatatccc ctgctgaaag ccgaacaaga tctccacaga cgatttcttc
    38341 cataggaatc tctgtgtact ttccattacg ttttacagct gccgttactt tcacaagtga
    38401 tttcagtttt tcagccgctt gattggaacg tacggactga atcaacgtca ttgtcccgct
    38461 gacgataacc atagtgaaga taatggctac accgaaaaga tctttatctc caggagctgc
    38521 taatacatat tccgtgatga atgaaataat tcctaatgcg atcaacacta atgtaaatgg
    38581 cgtgatgtat gctttcaata tttctacaat gaatggtgtt tttttgccat atgaaatcgc
    38641 attttcaccg taattttctc ttgaacgttc gatttgttct tctgtcaatc catttgctga
    38701 tgcatggaat agttcaaata attcttgttt cgtttttcca gcaaaagctg catagatttt
    38761 ttgtgtatct ttcttttttt ccatctcaat ctctcctttg tgtccaaaag acagctgttc
    38821 tcgctgcttt tggtctttag ctattcatcg gatcgataga gaaaaaactg aaaggggctg
    38881 agaacagata gataatagcc ctggcctttc ctctagatcc ttgtttttcg aatgactgtc
    38941 atccatttgt tctcatctcc tttactaagt aattttaatt catgacttcc aatcattttt
    39001 cgaatagtta tttttccaat tagaccacct cctttttatt tttcaccgat ggggatttgc
    39061 ggcaacaaaa aaacctctcg ccaaatactc agcgaaaggt ttgaaaaagc atattaaaaa
    39121 aagcttctca gatctcatcg ttgagttttg acactgtaca acgtaaaaag cagatacctg
    39181 cttttagcta ccttatgaaa agccttatct cgacaattcc tgttctaccc attggcgtct
    39241 ctcgacgttt ttgggcagta gcctatgttt gtataggagc ctcacctaac aaatcttatt
    39301 cggttttcct tcgttaatat aacaactaaa aaagaggatg tcaaatcaat tttccatgtt
    39361 tttcatactt tttttaaaat acacacgtta tattcctgtc tcacgcggtt ttatttgtct
    39421 cattttccac ctcccgctat aatagaaata tagtaggaaa cgaggtgctg ttatggaaag
    39481 aacacttgtt attatcaagc cagacggcgt gagacgccat ttagtcggaa gcatcatcca
    39541 acgttttgaa gcaaagggac tggccattgc tgaaatgaag tttgaaacta tgactcctga
    39601 attagcaaaa gaacattatc agcacttgac tgagcgcagt ttttttgatg aactgatcga
    39661 ttacatgact tccggtcctg tcgtttatct tgtgctggtc ggcgaggaag tgatcgatat
    39721 cgtccgtaag atggttggag caacaaaagc tgccgatgct gttccaggta cgatccgagg
    39781 agactacgcg ctgccgggga ctgaaaacat cattcacgct tctgattccc gtgatgctgc
    39841 ggtaaaagag atcgcccgct ttttcccgcc attcgatata aacaaaccgt ctgaaaaagc
    39901 ggcgaagtga tacaaattct aaactgctgg tctagttgct gggttcagca atggccagca
    39961 gttttttctc taaggacctc cgttgattct ttcctaacat atattcgagc actgtgaaga
    40021 attcttggta gtctttcgtc ttttcttccc ctaaagcagc agaaatcaat ctttgataat
    40081 aatctgccat caatgtttca tagatcactg tacttctttc tttatgtgat aagctccgtt
    40141 tcatatcttc attcacacta cgtgcctttt tcaaccgacc attttctata taaaacgaag
    40201 tcaggttcat taaaaaagta aagagatact gctcatgatt gttcaactgt gctaatcgtc
    40261 gcattctttt tttgattttc aaataattgt tctcaatgaa ccgatcactg aatatccaag
    40321 gaaaatcagc tagaatagat agttcaaatt gaccatagtc tggtatctgc atcaagtatt
    40381 cttcaatgat tcggcattca taacgtaaaa attcaaattc tgtctcagat acttctgttt
    40441 tttcgaccat gtgaagattc aaaaccaaat aatacagatc ttctgttttc ttaaaatgcc
    40501 tacggttatt gctgatctct ttataaggat caaagctgtc ttcttgtacc cgatctagca
    40561 ttcgtctttt tttctttaac tttattggtt catccagctg gtttcgcatc cattcatatt
    40621 ctgcaagtgt catgttcatt cgctctaaaa atgatctcaa tgttacaaat gacatttttt
    40681 tcactgaatt tgtctcaatc ccgactagag aagtcttaaa acagattcct tccgctaatt
    40741 gggactgtgt caacttcttg ttgactcgaa gtttcttgat caattcacca tcatacataa
    40801 tagttctcct ttttaattta aatttttcca cattcaataa atagatacgt taaaaaggaa
    40861 aaatacacga aaaaaataaa aaaatgtttt tttcataaaa aataccaacc ttcaagcatt
    40921 agaatgttgt ctaactactg aaggttggtt tgattgttta ttgattattt ttttgctgtt
    40981 caacgtctgt tcttgttact ggatataagt tggttgttgt tttattacca ttttttgaaa
    41041 agacacttgt cgaatgttcg cctttttgct tttcgattgc ttcattacgt tccgcttcat
    41101 ttttatagtc atattttttc ggatcaatcg tctcaaatcc gtttggcaca taaaaccgca
    41161 agagattttc ctgattcagc ttatctgaaa gacttaacgc agtcttgact ttttcctgat
    41221 ctttggagat ttcctcatcg attcctgctg ctttcgtatc gatgatttct cctgtctgat
    41281 tattgtaagc ttttcctcct aggacggtgt atttgggtgt cacaaagttc ccatttcgaa
    41341 aagcaactac ttgatcatgc tgagaagata ataagtctgt accaaaatga agataatctt
    41401 tatcatcgat tcccaataga tgtagtaatg tcggcaaaac atcgatttct ccaccgtatt
    41461 catgattgac tgtcccttta gtataaccag gcatatggat catcaatggc actcgttgca
    41521 tctgtgcgtt gtcaaattca tcccatgtat ctggatcttt accaagagcg cttgctaaat
    41581 ctttattatc tgtattcgag atcccaaaat gatccccgta aatcacaaag attgaatttt
    41641 ggtaaatacc agattttttc aaatacgtaa aaaattgttc caatgattga tccagataat
    41701 gtgccgttcg aacataatta tctactgtgc tattgccagt attcaaagat ggaaagtcga
    41761 aattcttgtc atccgtataa taaggcgtgt ggttggttac ggaaagaaat ttcgtgtaaa
    41821 acggctgttg tagatgctca agatattggg cagattctct gaataaatct ttatctaata
    41881 tcccataacc taacgtttcg tcggattcat caaaataaga tcgatcaaag aaattgtcat
    41941 aacctaagtt tttatataca tgatctctat tccaaaaact agctacattc ccatggaaaa
    42001 cagcgcttgt atagccttgc ttttgtccaa ggatcgctgg tgcggcttga aagacattgt
    42061 ctgacccaag ttctgtgaat aatgagcctt gaggtaaacc aaatgtgcca gtttccaaca
    42121 tattttcagc atcacttgtc tttccctgtc ctacttcatg aaagaaattg tcaaagctga
    42181 tcgttgcttg attctggaaa atactattta aaaacggtgt gacttcttgt ccgtctacct
    42241 tcatattaat caaaaactgc tggaaacttt ctaaatggag aacgatcaca tttttccctt
    42301 tagcgatccc aaatgtttcg ggatttggct ctgcataatg tttctttgta taatctaaaa
    42361 cttcatcaat cccattactg cttgcatgcg cgcgaacact gctagtcatt cctgttttga
    42421 ttccgtcata aatagtatac gcatcgattc ctagatattt gacaatatat gaacggtcaa
    42481 atgttcgctg cagcaattgt ggacggttgg cttcgctcag cgctagattt cctgaaaaaa
    42541 taagccctga aagacaggta acagcgatag ccatcggttt gccgacaggg ttgcttttga
    42601 taggtatttt cttgaccttc aaccaaacca gtagcccaat gaacacagcg atatccagcc
    42661 agtagatgac atcatggggc ttcatcaaag aaaaggagct tcctgacaat ccttgcgaca
    42721 ctttcgaaaa gcctaataca gatttgactg taatgaaatc tgtgaattcc cgataaaaaa
    42781 taatattcaa gtacaacaaa agcgtattta aaatatcaat gatcaaaaga atagctaacg
    42841 ctggctttgg ctttttaata tacaaagaaa ggccaaaaaa caataaggta gtcgcaattg
    42901 ggttgatcca caagataaag tactggatcg taccttccac acctaatgaa aaatctgcat
    42961 agtaggcaat gatcgtcttc agccagaaaa agaaaacagc tgtcaaaacg attgctaaac
    43021 gattttggca caatttttta agttgtgtca cgtatatcac ttctctctat tcacattttt
    43081 tcttattttg ctcctgaaaa atgaaaattt cctaaaaaag ttgttatctt aagatttttt
    43141 tattctttct aaagattatt ccgtccactt ttcacagcat aaaaccgctg cgatgtaagc
    43201 gattaaacta atgaagagat aaaagtcttg tggtgaccgc ttcactccac ggtattcaaa
    43261 agccagtttc tcggtattcg tacaaaaaaa gaggctgtga caaaattctt gtcgcagctc
    43321 cttatttctt gatgcaggac agctttttca caacttcttc cttaaacggt gttctcctgc
    43381 caactcctcg gccacaagtc acaatattta taaaacatga gaagctgttt tttgaaattg
    43441 ttccttgtgg ctcagagtta aacggcaggc tcaagacctc ttgatacacg gtgttcaatc
    43501 agctgaccct cggtattaga ttatgtcagg acgctaattt tacaacctct tggtaaacgg
    43561 tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat aaggagctat
    43621 tttttgaaat tgctccttgt ggctcagagt taaacggcag gctcaagacc tcttgataca
    43681 cggtgttcaa tcagctgacc ttcggtatta gctcaaaaaa cggcaaaata tgaggaacta
    43741 ttttgccgtt tgtttctcta atactcaggt caaaacgctg atttcacaac ctctgttttt
    43801 cattgtccat aggattgata ttgtccttgt gatgactcat tcgtaataat tgaggcttga
    43861 ttttcttcac ttcccgttat cgtttgtcca ctgccagaat ctgaaggact tgttcctgtc
    43921 gactcgtttt tttgagaaga gacagttgtt ttcttgactt gttcatttgt ctttttccat
    43981 tccgctaaac gatcggcgac cacttttttg tctacttttt cagaataagc ggtgatcact
    44041 tttccatttt tcaaacgggc tactttgtcg ccaacatgag tcaaaagcaa aacggtcaaa
    44101 tgcttgtctt taaattgata ttgtctgaga gaaatcgcac taagtacgtc atcgatatta
    44161 ataaattgat tttcttcttt tccttttggc aaataaatgt ccaattcgcc tttttcgtaa
    44221 ttggcagtta ttttatactc cgcccaccaa taagttgaga attctttttt gaaattatct
    44281 actgattctt tgcttgctac gattttttct gtttctttct gagcaagatc tgctgtcatt
    44341 tttcctgaaa atgctgcgga taaaataagc agtaagaaaa aaccgaataa ccaaaagaga
    44401 agaaacggtc tttttttcct catgctttcc tccactccta tttaattttg actattctat
    44461 tatatacaaa aaatgaaata gaaagacaaa aaagttgaaa aagatcgtaa ataattgaac
    44521 ttctttttca caaaatggta agaatggaga atttcacgca tttgctctca actattcttt
    44581 cttaagcctc aaatccgttt ttatctgata cgtctttgaa ccaatgaccc gattttttga
    44641 ttgttctttt tccatcttgt gctaagtcta ctgaaataaa gccatatcga ttcttatatg
    44701 cattggtcca cgaccagtta tccatacatg tccacatatg atagcctaaa caattggcac
    44761 cttcttgaat ggcttgatgg acatatttca gatgagattg gacaaattcg atccgataat
    44821 catcgtggat catgccatct tctttgataa atcgtgcttc gttttctaca cccataccgt
    44881 tttcagaaat aaagcagtcg atatttccat aatgatctcg tacattgatc aaaatatcat
    44941 agattccttg ttcatagatc tcccatccgc gataaggatt cattttacga ccaggcattt
    45001 cataattgtc gaaataatcc tcaggcattg gaccgttttt agtatcgatt ggtgtttctt
    45061 ttgcttttac ccggcgtggc tggtaataat tgatacctaa aagatctact gtattttctt
    45121 tgataaccgt caaatcctct gcatggatca caggcatgag atcaagttct tttactatct
    45181 caatcaattc acttggaaac tcgcctttta cagctggatc aaggaatgaa cgattgaaga
    45241 acgcatctgc tatttgcgct gctttaacat cttcagggtt tgattcgtct cttggatagc
    45301 ttggtgtcag attcaagatg ataccaataa caccaccttg ctccatttca tggtaagatt
    45361 tgatggctaa cgctgaagcc aacgcttcat gatagccaac ttggatcgct tttttcatat
    45421 ctgactcttc tggataatgc catcgatata aataacctgc ttcgactgga acgattggtt
    45481 cattatgagt aaaccatttt tttactttcg aaccaaacaa ttcaaaacaa cttttggcat
    45541 atttttcata ggcttcaacc gtttctcggt tcaaccatcc gcctttttct tgcagataca
    45601 tcggcatatc gaaatgatac agattcacaa agggttcgat accgttttca atcaactcat
    45661 caaaataacg atgatagaaa cgaacggctt cttcgttgat tgttccagat tcatcaggta
    45721 tcaaacggct ccattggata gatgttcgaa atgaattatg cccagtctgt ttcatcaact
    45781 gtacatcctc ttgatacttc gtataaactt gcgaggtttt ttcaggtcct acttgatcaa
    45841 agaacttttg cggttctttt ttgtaccaat aatcaaaaat gttctctcct tttccatcgc
    45901 ctgaaatcct tccttctgtt tgtgggccac ttgctgcaga accccaccaa aaatttgctg
    45961 gaaattgata ttttttcatc aaagcacctc tttttctttt ttagttcgtt ttagttgatt
    46021 ccatgtatga tattttccat cacaatcact ttttcatttt cttcctcttc ttttttgatt
    46081 cgttttaaca gctgttctgc tgctcgttcc ccgattttat ctgttggtgg cgtgatcgtg
    46141 attttcggaa ggatactcag atcgttttta tctaaataat catagtgact gaacgcaata
    46201 tccttcccga ttctgacacc ttcttgattg aaacattcga tggcaccaat cgacatattg
    46261 taattgctga caaaaatagc agttgcccct ttttctaata atgcttttgc cccgtaatag
    46321 ccgctttttc tagaatagtc tcctgtaaag acctctaatt ggatcgatgg atcattttgg
    46381 accgcttctt tggctcctgc taaacgttct cttgctacgt agtctgtttg agtggcagca
    46441 ataaatccga tttttttatg tccttgttca ccatgatgag cgatcacttt tgctacactt
    46501 tctcgatcat tcactaatat tgtatcaata cctgctggtc cttctggaca attcaatgcg
    46561 ataactggaa tactcatttt tgtgagcatt tcaaatccag accactcttc ttcggataag
    46621 aagacaatca gcccatcgat cacatgcttc atcaggtatt caattttttg ttcaattttt
    46681 tctggctgat cggcaaaccc gcttaataat aagctatacc cattttcttc agctactctt
    46741 tcgatccctg agacaacttc cgacccaaaa cggctggaaa tcccgtttat caaaagtcca
    46801 atagagaagc ttcgattatt cttcaaccct ttagcaatga tgttttcttt atagtccaac
    46861 gctgaaatcg cttctgctat ttttttcatg ttcttttcct tcagttgctg accattcaag
    46921 taacgggaaa ctgttcccac tgaaacacca gccatcttag ccacatcacg gatcgatgcc
    46981 atacattctc actcctgcca gttacatttg atttctcttt cttgttgttc gattatgatg
    47041 accgcattct ttgcatagtg ttgcttgtca tcaatatcca tataactaaa gtcttcagta
    47101 gagcaacttc ctctcactat taattatact taaacaagta tttgaaccgg ttcattttta
    47161 atatagcatt tttttaaaag attgcaacac ttttttaaaa cgctttctga aagtggcgga
    47221 ttttttgcct ttttaaaatt ttattctaaa atttactcta tttgtgggtg ttttgtgcgt
    47281 ttttctcttc catccgtttg aagttttaca ttccaatggt ataatttctt tatcctatca
    47341 aatgggggaa gtattttgaa gaaattaatc gtactattta ttttgtctgc gggacttttg
    47401 acattgactg gctgtgattt gtttggcggc tctgaccaat cctcggacga aacaaccgat
    47461 tcttctgtct taaaagcgga aaaagcagat accaccaaca gtgtatatac gctaaaagta
    47521 cgtaaagata tggatttatc cgcgggacag ttgacattta cagataaaaa aatggaatgg
    47581 acacgcacgt atcagacaca aggaactgat tcttctgaat catctgaaga aaaaacagtg
    47641 ctgacagata tcaagatcac taccaaagat gacgaatata ttatttcagg aaaagaaaat
    47701 aaaaaagaaa caacagtcat atttacaaaa atcggtaatt accgtttgaa ggatgaggat
    47761 ggcaacatct acagtctata gtgccgtctg ttggatcttc ttttgtttct ccccttcttt
    47821 tctgctatag taaagaagca agatgattgt aaaggagacg aaatggatga tcgatagtcc
    47881 tgattattgt acatgtaata acaacaaaaa tatccataca gaatttaatg accaaggaag
    47941 cttgagcata tgcgacaact gtcacaaact agtcaaagat tcatttaaaa catttgaatc
    48001 ttatcctgtt caaaattatg taaaaagtag aagaagataa acaaatccaa gcaaaactca
    48061 ctatggctga tttttatgaa cttcaaactc agcttcttcc tttgatcaag cttcatcagt
    48121 aaaacaaaca gtggatcatt tcagtttaca aatcaaagag taaagattta tttatttcaa
    48181 atatttgaat ataaaataac caaacgatag aaaggcttat tctacatcac gtagtaattt
    48241 ttctttcccg tcgtttggtt ttttattttt agcctaattc ttgacctttt gcatgctggt
    48301 tatccgtaaa atattttcca gcaggctttc cttccaattc agctaatttt tcttggatct
    48361 gacggatcac cttttttgca tcttctggat tttctacaaa atcgaattta tccccatcca
    48421 cttgtatttt aggacataca tcaaaatctt cataccattg attatagcgg gtgttcaacg
    48481 tttcataata ggtatataac gtctcatcgc tttctagctg ttcatagtca cgcccacgtt
    48541 ttttgatacg ttctagcatc gtgtccaaag aaactttgat atggaccatc aaatcaggcc
    48601 gtttttttgg agcaacatca tctaactcgt ttagcatcgt atctaataag ctatcgtact
    48661 gctgtacttc gatatccgtt acccgaccta aatcagcgtt tagatggaac aacaggctat
    48721 cttcatagat ggatcggtct agcacattgt catcgttcac taaagcattt ttcattgcta
    48781 aaaatcgctt gttcaaaaag aagatttgca ataaaaaagc gtactgctca ggatttgaat
    48841 aaaagagcgg caatacttcg ttatcttcga cattttcata aaatggttta gaatcaatct
    48901 cttttgcaag catatccgtc aaactgctct tacctgcacc aatcgttcct gaaatcaaaa
    48961 tcactgacat acaacccttc ctcttctata agtactcgcc tacgtaagtt tcaacaggca
    49021 atgtttcaaa atcatattca cgtacagctt ggtctgattt taaatacgta tggagacttt
    49081 gtgtaatcat caagttcgta ggtaccgtct cttcttgtac aatgatcatc ggttttttca
    49141 acatagttgc cacacctaat tcgtaagccg ttcctggatc gattgtttga tgctcaaagt
    49201 caaggatagc aacaacaaat tctgcatttg tcagttcttc catatctttt tcgtatactt
    49261 cctgcgccca tccagcgctg aatagttcat aattgctttc ttggtgatga cgtggagagt
    49321 agaaacttgt gactgttttg ttttcctcca acgctttttc gatacgactt actcgatcga
    49381 tttgctcctc tgaaaaaaat ggtcctgcta aatatatttg actcattatt ttgcctcctt
    49441 caataataac tgatttttaa tagatactgc tcgtaattca ttgaccagtt ccaatggatt
    49501 gttggaaaag attacttgat ccaaccattt tttatccata aaatcctctt ttgcaaaagt
    49561 ttctaataat tgttgcaagc cgctgtaata accgccaata ttcaatattc cgattggctt
    49621 gtcgggcgtc agaccgattg ctatccaaga aagaagttgt gagaattcct ccaatgtacc
    49681 tagacctcca gggaaaacga ggacagcatc tcccttttca aataataata cctttctttc
    49741 atcgatcgtt tctgtaggaa taaatgtagt aacatctttt ccaggcaatt cagtttcaaa
    49801 aagcccattc ggatagatac ctgtgacttt tccgttattt tccagtactg ttttactaat
    49861 cactcccata atcccggagt atgaaccacc gtaaaccagt tcgatttctt cttgtgccat
    49921 gtattttcct aacgtttgcg caataaattt gtaactttct ttattaccaa aacgggaacc
    49981 gcaaaaaaca gtaagtttca taaaaaaaca ctccctaact caaaagtcta tcttcattct
    50041 acacgtgttt ttttaaaata aaagactaga ttttgtagtt ttttagtggt atataggata
    50101 gacgccacta tatatagtat ttagaaaaaa atcatttttc agccatttta tagataaaac
    50161 aaaaataaat aacgtgtttt catcgatatg aaatgactta cttatagaag atactgggat
    50221 ttcgtcctat atgccaataa cgtgtattat tttaaacaac aaatacttgt ttcttttatt
    50281 aacgaaaaaa tcattttgtt ctcgtgttat gtttcactga taaatgatgt ttctctaaat
    50341 aaaaaagccg acgaactaaa cgatcaaaat ttgatcattt ttgttcatca gcttctccta
    50401 aaaatctttt tgttaacgat aaatagctgg atttgtaaaa atatcacttg aatcgtcact
    50461 gctggaagaa aattcagtga taaccgcacc tgttgcgcct gcctggaact agtgtttgat
    50521 attgggctcg aacgtgtact gatctctagc atgaagaata atttcttttt ttactgtata
    50581 ataactttct ttcctttttg gaatagtaca ggaaagtttt tttgtttcct ttccttcgac
    50641 ataaggtata ccagaccctt tcgacaacga aaggttctca tttttccttc atcgtcattt
    50701 caaggagggt gccgatgctc tggacagttt cgatcgctcc taaaccaaaa tctgtatatt
    50761 cgattctttc taactctgat tctttcatac cattcctgtc tcaaggtaca tctattgtac
    50821 ttttttcttg taatccattc tgcctctcct aactaattgt caaatcatcc caagatatgt
    50881 cttcttcctc tttttcttct tggatgattt ctgcattcgg atctactggt tttttcaata
    50941 ataaaatggt tattcctgtg acaaaagaac cagctaacaa tgcaccaatg aatgcccatg
    51001 gtctggtcat cgtagcgact gcaaacattc ccgatgccgg aatacggcta tctgcgcccc
    51061 aaaacatgct taatccgcca cctactgtcc caccgactcc cgttgctatg acattgcgtg
    51121 ccaagtcgtt caatacgata gggaaacatc cctctgtgat ctgacagatc cccataggaa
    51181 aagcggtctt caatgtatcg atttcttgac gattgagtat atttttacga atgattttcc
    51241 ctaagaaata agcgatcgtc aagccgaatg gggttaccat cgaagctaaa atcaatacag
    51301 tgattggttc atagattcct tctgaaaatc gtgccacacc cccttatcca gaataaatgg
    51361 taatccagaa acagccgtgt atctgcggta ataagcctaa ccaaacgaaa aatatgagaa
    51421 gctatttttg tttggctgtt cttattactt gatgcagggc agctttttca caacctcttt
    51481 ttttatttat gtttcataat caatatggta aggatgcagc tccgtatggt agaccgcctc
    51541 cgaatattca atcatttccc caatttgcgt agacgatttc cgtatccgtt tgatgccgat
    51601 ctgtgcgtct gttttcagaa ttccttgttc ttcttctgtt aaaaatactg ccgagaaatc
    51661 atcagaaaat gagtcaatag tatatccttt tttcgtcagc aaacgataca aagattcttt
    51721 gccaaattct tctctgctga attgcatcat ttcttgtgga agataatgaa caaaataaat
    51781 ataaggctga ttgttcaaat aatataagcg cttaaaacaa acagcttgct caccgaaaaa
    51841 ggaaaacaaa ggatcttcct tctttatatg gaccaattgc aaatccagcg tttctttccg
    51901 gacttcatat cgggagttct ccaagatttg cgtaaagctt gccgctttgg ataatcgatt
    51961 gtaaggacga ttgcttagaa ccgtcgtccc acgaccactt ttctttgcga catattcatc
    52021 tgatgccagc agttcgattg cctttcggac agtgattttg ctgacttgaa acagttcttc
    52081 taattcactt tctgtcggca acatcgaacc gactggatat tttcctgaga aaatatcttc
    52141 tttaatttta tctgcgactt ccaagtatag tacacgtgtc cttttcataa cgtcaccctt
    52201 tgctttacta ttactaaaag aatagcacat aaaaaataaa aaaagaacac aaatcacatg
    52261 tgagaagtgt gttctttttc attcagctgc tttaattaca agtttacgcc atttgaggca
    52321 attacttctt tataccaatc aaaagatttt ttctttgatc gattcagtgt cccatttcct
    52381 tcatcgtcta gatccacata gataaagccg taacgtttac tcatttctcc tgttgatgca
    52441 ctgacaagat cgatacatcc ccaaggcgta tagcccatca aatctacacc gtctgctact
    52501 gcattagcca tcgcttcgat atgacgacgt aaataatcga tccgataatc atcaataatc
    52561 gtgccatcct cttccatatg atcaatggct ccaagaccgt tttcaacaat gaataatggt
    52621 ttctggtaac gattgtataa ttcattcaat gcgattctca gcccttctgg atcgatctgc
    52681 cagccccatt cacttgcctc aagaaacgga ttttttactc ctcccagcaa gttcccttct
    52741 gaagttgctg cttgtggatc agtctcattg attgccgtag acatataata actaaatccg
    52801 atgtagtcca ctggatattc ttttagcaac tggaagtctt tttccgtttg ctctaatttt
    52861 tccggatcga ctccatattt tttatgggta cgcgctgtgt atgcagggta ttctccacgt
    52921 acttggacat ccgtgcagaa aaaattgaat tcttggtttt ggatcattgt tgctgcctga
    52981 ttgactggat tggcatcgat gctgtaagtt gttgcataga taatcatgca gccgatttgg
    53041 atatccgaac gcaattcgtg gccgattttt acggctttgc tacttgcaac gaattgatta
    53101 tgccatgctt ggaaaatatt ttggtactct cctgctccat tgctttttac taatccttga
    53161 cttaaagctg gaaagtgaaa ggccgaattg atttcattga aagtcatcca atatttgact
    53221 ttactgctgt atctctctaa tactgtctga gcaaatcgtt catagaagtc gatcagtttt
    53281 cgatttttcc agccaccgta ttcttttgcc aaatgaagag gcatttcgta atgagaaatc
    53341 gtgatcacag gttcaatatc atattttaag cactcatcaa tcagctgatc ataaaattct
    53401 aatcccgctt cgttaggagt accttcgtct ccatttggaa aaattcgtgt ccaggcaatc
    53461 gaaaaacgat aacatttgaa tcccatttcc gcaaacaagg caagatcttc tttgaaacga
    53521 tcgtaatgat cgattcctcg atgattcggg taaatatatt tttcttgatc aatcgtccag
    53581 tcaaattctt cactgccgat aatcgcaaag cgctgcttac ctccaggcat agcatctgca
    53641 acggatagtc cttttccgtc tcgatcataa gccccttcta attgatttgg cagcagttgc
    53701 tccaccccat aaaaattttt ctgaaaaacg tgattgcatc ctgatttcct ccttatttta
    53761 caattgccag aacatcttcg tttgcaataa tctctttttg gtctaattca agtatatcgg
    53821 caaatgcatc agtattcgta atgacaactg gagtgattac gctatagcca gctgctctaa
    53881 ttgcttcgat gtcaaaacga atcaataaat ctcctgcttt gacgagatcc ccttgtttga
    53941 ctaagatctc aaagccattc ccatttaatt ctactgtatc catcccgata tgaatcaaaa
    54001 tctccgctcc gtcagtcgtt gtgatcccta cagcatgtcc agttggaaaa atagtcgtga
    54061 tctctccgtc tgcaggtgca actagttctc ctacttctgg atcaatagcg ataccttttc
    54121 ccatcacgcc agaagaaaaa acttggtctg gtacttcact caatggcagt actttacccg
    54181 ttaaaggact ttttaaggta tgccgtgctg aagtaatcgg ttctcctgca ttcgcatgtt
    54241 tgttttctaa ttgattgtct tgtgtttgtt cgtcaaatcc taaaatcaat gtacctacga
    54301 atgcaagaac aaaagcaatt cctgtagcta ttactgctac tgtcacattt gactctacac
    54361 catccaccgt attaatgaaa gtcggaatcg tcaataagct gaccaaactg ctggagaaag
    54421 cttttactcc ggaaaatccg ataatagctc caccaatacc tccagaaata caagcggcaa
    54481 tgaatggttt cttcaaaggt aatgtcacac catacacagt tggttcagtg attccaaata
    54541 acgaagtcac tgtagaagaa atccctaatg ctcgaagttt cgtatctttt gttcgcaatg
    54601 ctacagctaa agcagcccca ccttgtgcca agatggctgg aagaagcatt ggcatcaata
    54661 catcaaaccc atattgttcg atattcaaaa acatgatcgg tacgaatccc caatgcatgc
    54721 cgaacatcac gaatacttgc cataaacttc ccatgattag acctgctacg attggactaa
    54781 atccataaat cgagttgaag agaccgccta aagcattacc ggcaaccgtc ccgattggtc
    54841 ctaaagcaag aaatgttaat ggaaccatca ctactaaaac gacaagcgga actaaaatca
    54901 tttgcagaaa ttgcggaatc acttttttta cgaatggctc taatttactt tgaacccata
    54961 cggctagaat gattggtatg acagaagaag tataaccaga tggtgaaaga atcactggga
    55021 tcccaaagaa actgatagct tctcccgcac cagcaactgc tgtgatagct ggatacacaa
    55081 gtgccatagc aattgctact gctaaaaact ggttggcttt gaacttttta gctgctgtaa
    55141 aagcaagcat gacaggtaag aaggtaaaga caccatctgc tgcagcaaac aatatttgat
    55201 aagtaccgct atcagctgtc agccagccca tcaccgttgc caatgataag aatcctttca
    55261 ataccccggc ggctgccatc gcccctagaa aaggtgtaaa tatactagag ataatatcga
    55321 tcagacgatt caaaatattt ttggactctt cttttccatc ctccgaaact gcaagacctt
    55381 cctcatccac gatcgattga taaacatctg ctacattact gccaatcact acttgatact
    55441 gaccgccact ttgtacgact tggatcacgt ccgggtcttc ttttaacttt tgcgtatctg
    55501 ctaaagattc atcttttaat ctgaatcgca accgcgtagc acaatgtact aaacttttga
    55561 cattcttttg tcctcctacc gcttcccata cacgacgacc aactgcttga ttatccattg
    55621 ttttttcctt ctttcttttt tatttaaaaa ataaaaaccc agattgaaaa aaacagtcac
    55681 aaacattcgt gaacctattt tttcaatcca ggttttgcct gccatacagt aacaatcctt
    55741 atgattggat gctttttttc tcacttacta ctctttgaat atgaatcgtt aaataaatct
    55801 gctctgcgat ccccatttcc tgtttttgcg tttgtcgaag atactcattg atccgttcga
    55861 cacaatgaaa cgcttttgga tactttcctt gaactaatgc gtagagaaat tcatcttgct
    55921 cgtcagatcc ttcccctttg agataacgct gggcaaaaaa ctgcagatga gtaatgatac
    55981 gctgataatt caaagattct tcatcgaaca cgatgccgaa gaatttactg atgatactca
    56041 gtatatctct taccattgtg gtagcggtca tcgtcacttg catgtcttcg tttccttgtt
    56101 ggctattcac aaaatgaaag gcaataaaac cggcttcatc ctcagaaagt tccacacccg
    56161 tcttttgttt cacgaacaaa agagcctctt tcgctgcttg atattctttc ggataaaatt
    56221 tttttgtttc aaataataat ggattaggca gttggatatt ttcttttgct cgtgtgatcg
    56281 cataatgaag atgatcggtc aatgtcagat aaatattagg cgaaaattca acttttagtt
    56341 tatcttcagc cagttcgact acttgtttga cccattcgat ctcctctgcc ggaatatcag
    56401 ccatcagctg ctggaattgg tttttagcaa aagaatctct taaaacaaat tctttttgga
    56461 ccgcttctgg cgaaatctcg tccccaatct ttttttgaaa agctagtcct tttcccatac
    56521 aaacgacttc ttccccgaat ccatttttcg aaatgacgac attgttattc aaaattttat
    56581 caattttcat tttgcttcgc cctctcaaga aaaataaaaa aacctagaat tcgcctactg
    56641 tttcttagct gaattctggt tttgcctgcc gtacagtaac aatccatttc ttattcaaaa
    56701 tcatcatacc atcgaatttt tatttatgca agccttttca tataaaaaat aaaaaaactg
    56761 gaacacaagt ctatctagaa aa
//
LOCUS       DAZKNV010000012        52448 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000012 DAZKNV010000000
VERSION     DAZKNV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.012"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..793
                     /locus_tag="ACG8M1_000811"
                     /pseudo
     CDS             1..793
                     /locus_tag="ACG8M1_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            933..1859
                     /gene="cysK"
                     /locus_tag="ACG8M1_000812"
     CDS             933..1859
                     /gene="cysK"
                     /locus_tag="ACG8M1_000812"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFQ0421545.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2095..2541
                     /locus_tag="ACG8M1_000813"
     CDS             2095..2541
                     /locus_tag="ACG8M1_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0421546.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2813..4165
                     /locus_tag="ACG8M1_000814"
     CDS             2813..4165
                     /locus_tag="ACG8M1_000814"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFQ0421547.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4336..4623
                     /locus_tag="ACG8M1_000815"
     CDS             4336..4623
                     /locus_tag="ACG8M1_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0421548.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4849..5292
                     /locus_tag="ACG8M1_000816"
     CDS             4849..5292
                     /locus_tag="ACG8M1_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFQ0421549.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5298..6482)
                     /locus_tag="ACG8M1_000817"
     CDS             complement(5298..6482)
                     /locus_tag="ACG8M1_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFQ0421550.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6750..7448
                     /locus_tag="ACG8M1_000818"
     CDS             6750..7448
                     /locus_tag="ACG8M1_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFQ0421551.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7455..8132
                     /gene="nth"
                     /locus_tag="ACG8M1_000819"
     CDS             7455..8132
                     /gene="nth"
                     /locus_tag="ACG8M1_000819"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFQ0421552.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8258..8791)
                     /locus_tag="ACG8M1_000820"
     CDS             complement(8258..8791)
                     /locus_tag="ACG8M1_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421553.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9088..11469)
                     /locus_tag="ACG8M1_000821"
     CDS             complement(9088..11469)
                     /locus_tag="ACG8M1_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFQ0421554.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11459..12106)
                     /gene="recU"
                     /locus_tag="ACG8M1_000822"
     CDS             complement(11459..12106)
                     /gene="recU"
                     /locus_tag="ACG8M1_000822"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFQ0421555.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12170..12709
                     /locus_tag="ACG8M1_000823"
     CDS             12170..12709
                     /locus_tag="ACG8M1_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFQ0421556.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12799..13218
                     /gene="gpsB"
                     /locus_tag="ACG8M1_000824"
     CDS             12799..13218
                     /gene="gpsB"
                     /locus_tag="ACG8M1_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFQ0421557.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13240..13607
                     /gene="rnpB"
                     /locus_tag="ACG8M1_000825"
     ncRNA           13240..13607
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACG8M1_000825"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13816..14982
                     /locus_tag="ACG8M1_000826"
     CDS             13816..14982
                     /locus_tag="ACG8M1_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFQ0421558.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15028..16524
                     /locus_tag="ACG8M1_000827"
     CDS             15028..16524
                     /locus_tag="ACG8M1_000827"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFQ0421559.1"
                     /translation="MKEKEFLQEVKEINLLQKALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16605..17288
                     /locus_tag="ACG8M1_000828"
     CDS             16605..17288
                     /locus_tag="ACG8M1_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0421560.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17933..19123
                     /locus_tag="ACG8M1_000829"
     CDS             17933..19123
                     /locus_tag="ACG8M1_000829"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFQ0421561.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19225..20178
                     /locus_tag="ACG8M1_000830"
     CDS             19225..20178
                     /locus_tag="ACG8M1_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFQ0421562.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20247..21596
                     /locus_tag="ACG8M1_000831"
     CDS             20247..21596
                     /locus_tag="ACG8M1_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0421563.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21779..22102)
                     /locus_tag="ACG8M1_000832"
     CDS             complement(21779..22102)
                     /locus_tag="ACG8M1_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421564.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22231..23394
                     /locus_tag="ACG8M1_000833"
     CDS             22231..23394
                     /locus_tag="ACG8M1_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0421565.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23464..24813
                     /locus_tag="ACG8M1_000834"
     CDS             23464..24813
                     /locus_tag="ACG8M1_000834"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0421566.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24858..25289)
                     /locus_tag="ACG8M1_000835"
     CDS             complement(24858..25289)
                     /locus_tag="ACG8M1_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0421567.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25677..28319
                     /gene="alaS"
                     /locus_tag="ACG8M1_000836"
     CDS             25677..28319
                     /gene="alaS"
                     /locus_tag="ACG8M1_000836"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFQ0421568.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28519..29115
                     /locus_tag="ACG8M1_000837"
     CDS             28519..29115
                     /locus_tag="ACG8M1_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0421569.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29237..30385
                     /locus_tag="ACG8M1_000838"
     CDS             29237..30385
                     /locus_tag="ACG8M1_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0421570.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30423..30836)
                     /locus_tag="ACG8M1_000839"
     CDS             complement(30423..30836)
                     /locus_tag="ACG8M1_000839"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFQ0421571.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30915..31346
                     /locus_tag="ACG8M1_000840"
     CDS             30915..31346
                     /locus_tag="ACG8M1_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFQ0421572.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31445..31678)
                     /locus_tag="ACG8M1_000841"
     CDS             complement(31445..31678)
                     /locus_tag="ACG8M1_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0421573.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31861..33531
                     /locus_tag="ACG8M1_000842"
     CDS             31861..33531
                     /locus_tag="ACG8M1_000842"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFQ0421574.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33678..34064
                     /locus_tag="ACG8M1_000843"
     CDS             33678..34064
                     /locus_tag="ACG8M1_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421575.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34051..34749
                     /locus_tag="ACG8M1_000844"
     CDS             34051..34749
                     /locus_tag="ACG8M1_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFQ0421576.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34754..35218
                     /gene="lspA"
                     /locus_tag="ACG8M1_000845"
     CDS             34754..35218
                     /gene="lspA"
                     /locus_tag="ACG8M1_000845"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFQ0421577.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35215..36126
                     /locus_tag="ACG8M1_000846"
     CDS             35215..36126
                     /locus_tag="ACG8M1_000846"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0421578.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36361..36900
                     /gene="pyrR"
                     /locus_tag="ACG8M1_000847"
     CDS             36361..36900
                     /gene="pyrR"
                     /locus_tag="ACG8M1_000847"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFQ0421579.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36914..38197
                     /locus_tag="ACG8M1_000848"
     CDS             36914..38197
                     /locus_tag="ACG8M1_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFQ0421580.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38210..39136
                     /locus_tag="ACG8M1_000849"
     CDS             38210..39136
                     /locus_tag="ACG8M1_000849"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFQ0421581.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39155..40435
                     /locus_tag="ACG8M1_000850"
     CDS             39155..40435
                     /locus_tag="ACG8M1_000850"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFQ0421582.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40440..41516
                     /locus_tag="ACG8M1_000851"
     CDS             40440..41516
                     /locus_tag="ACG8M1_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFQ0421583.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41521..44706
                     /gene="carB"
                     /locus_tag="ACG8M1_000852"
     CDS             41521..44706
                     /gene="carB"
                     /locus_tag="ACG8M1_000852"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFQ0421584.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44760..45536
                     /locus_tag="ACG8M1_000853"
     CDS             44760..45536
                     /locus_tag="ACG8M1_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFQ0421585.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45533..46465
                     /locus_tag="ACG8M1_000854"
     CDS             45533..46465
                     /locus_tag="ACG8M1_000854"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFQ0421586.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46462..47178
                     /gene="pyrF"
                     /locus_tag="ACG8M1_000855"
     CDS             46462..47178
                     /gene="pyrF"
                     /locus_tag="ACG8M1_000855"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFQ0421587.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47185..47814
                     /gene="pyrE"
                     /locus_tag="ACG8M1_000856"
     CDS             47185..47814
                     /gene="pyrE"
                     /locus_tag="ACG8M1_000856"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFQ0421588.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47802..48116
                     /locus_tag="ACG8M1_000857"
     CDS             47802..48116
                     /locus_tag="ACG8M1_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421589.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48154..48795
                     /locus_tag="ACG8M1_000858"
     CDS             48154..48795
                     /locus_tag="ACG8M1_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFQ0421590.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48838..49530
                     /locus_tag="ACG8M1_000859"
     CDS             48838..49530
                     /locus_tag="ACG8M1_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFQ0421591.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49527..50429
                     /locus_tag="ACG8M1_000860"
     CDS             49527..50429
                     /locus_tag="ACG8M1_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0421592.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50587..52293)
                     /gene="efbA"
                     /locus_tag="ACG8M1_000861"
     CDS             complement(50587..52293)
                     /gene="efbA"
                     /locus_tag="ACG8M1_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFQ0421593.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17147 a         9139 c        11268 g        14894 t
ORIGIN      
        1 gaacgagtct tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag
       61 atgaacaagg atctcaaaca gttgctgatc ctcaagcgtt tatcgatcaa atcggctggt
      121 ctgcgtcaga agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt
      181 tgttggaaag tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg
      241 gtgtgaaagg aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaacgg
      301 acaatgggta acgatgaatg aaccattccg aaaatattct tcttattggg aatccttcca
      361 agaccatgcg aatgttcttc gttcaaccag tttttccacg ggcgattatc attatgctgg
      421 cgtgtggaaa agcaatacaa caagttttta tgatgcaaca gcgtacttga caggtcgtta
      481 tgctaccgat ccaaattatg gggccaaatt gaactcattg attaatactt ataatttaac
      541 ccgttttgat acgccatcaa caggttcggc taccacaagt acaacaacaa cgactactac
      601 gacgacttca acgtcatcat cttcaacaac agatgtaaat acaaataatg gtcagacata
      661 tacagtcgtg tcaggtgata cgctatggga tattgcacaa aaatttggca tgtctgttga
      721 tgatctaatg gcgaaaaatg gcatgtctat gtccagttat tctttattag ttggtcaaga
      781 actaaacgtt tgatttagat aaaaaggcaa agaaactacc atatatggta tatctttgtc
      841 ttttttttgc tagtcaaaga cgaatcactc gccataaatg aacagattgt attatgataa
      901 gtaagaagag caaagacaag gaggaattga agatgacagc tatctataac tcagtcaccg
      961 aattgattgg caaaacgcca atcgtcaaat taaataaaat cgtaccagaa gattcagcag
     1021 atgtttttgt aaagcttgag ttttttaatc caggaggaag tgtaaaagat cgtattgctt
     1081 taagtatgat agaaaaagca gaacacgatg gtctactgaa accaggtgat actatcattg
     1141 aacctacttc tggaaataca ggaatcggat tgtcgatggt aggagttgca aaaggatata
     1201 aagtaatcat cgtgatgcct gagacgatga gtatcgaaag acgtttattg atgaaagggt
     1261 acggcgcaga gttgattttg actcctggtg cggatggtat ttctggatca atcagagaag
     1321 cagaacgttt ggcaaaagaa aacggctact ttttaccatt acaatttgaa aatgaagcaa
     1381 atcctcttgt gcatgagaag acgactggtc ctgagataca tcaagcattt ggagtaaatg
     1441 gcttggacgc gtttgttgca ggtatcggta caggaggaac gatcactggc gctggccgag
     1501 aattaaaacg tgtgtatccg aaaatcgaat taatcggggt agaaccagca gaatctgcta
     1561 ttttagaagg gaaagaagcg ggacctcaca aaatccaagg aatcggtaca ggttttgttc
     1621 ctaaaacact ggatacttct gtgtatgata aagtcctttc tattagtgga gacgaagcga
     1681 tggaaacagc tagagaagtt gggcgaaaag aagggatttt agtaggcatc tcatctggcg
     1741 ctgcaattgc tgccgcgcta aaagtcgcaa aagaattagg aaaaggcaag aaggtattag
     1801 ctgtggttcc cgacaatggt gaacgttatt tatctacagc cctttaccaa gagatataag
     1861 gcacttggtt tttctccaga taggtttatg taaaaaactt ttaaagatga aaagaacaca
     1921 caaaaattta tgatgagaaa aattatttga atagagacgt aaaatagtga acgcgactgt
     1981 tttacgtctt ttttcattaa aatacaataa aattgaattt tcttttcatg ttaagtggat
     2041 tttaaaatgt aaaaatagta tgataagacg agaataacaa cgtggggtgt ttacatggaa
     2101 aataagttag tcgaagaggt tatcgaaaag ttaaaaaaag agaacattcg aatcacacct
     2161 caacggtacg cggttttaga atatttgatt gaacatcatt cccatccaac ggctgatgag
     2221 atttataaag cacttgaaca tcggtttcca aatatgagtg ttgcgactgt ttacaataac
     2281 cttcgcttat ttacttcgat tggatttgtt caagaaatga agtacggcga tgcttctagc
     2341 cgatttgatt tcagttcaaa gcgtcattat catgtaattt gtgaaaactg cggtaagatt
     2401 gttgattttc attacccagg gcttgaagat atagaaatgg ctgcgagcag actgactgat
     2461 tttgagatta atgaacatcg gttggaattg tatggactct gtccggattg taaagagtca
     2521 gcaaaaaagg cgcaaatgta aaaacagttt ctataagtgt tatacctaaa aaaagctagc
     2581 tgtgtaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatatca
     2641 aagtgaatat tatcacaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2701 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2761 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     2821 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     2881 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     2941 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3001 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3061 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3121 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3181 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3241 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3301 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3361 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3421 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3481 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3541 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3601 caaagtgaat gaatacatgc agacaagtga tccagacatt tttgcagctg gagactctgc
     3661 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3721 tcgtcaaggt ttacttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3781 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     3841 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     3901 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     3961 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4021 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4081 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagaagcgct
     4141 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4201 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4261 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4321 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4381 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4441 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4501 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4561 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4621 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4681 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4741 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4801 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     4861 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     4921 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     4981 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5041 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5101 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5161 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5221 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5281 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5341 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5401 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5461 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5521 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5581 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5641 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5701 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5761 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat
     5821 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     5881 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     5941 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6001 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6061 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6121 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6181 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6241 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6301 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6361 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6421 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6481 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6541 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6601 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6661 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6721 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6781 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     6841 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     6901 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     6961 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7021 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7081 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7141 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7201 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7261 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7321 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7381 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7441 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7501 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7561 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7621 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7681 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7741 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7801 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     7861 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     7921 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     7981 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8041 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8101 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8161 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8221 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8281 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8341 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8401 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8461 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8521 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8581 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8641 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8701 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8761 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     8821 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     8881 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     8941 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9001 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9061 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9121 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9181 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9241 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9301 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9361 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9421 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9481 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9541 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9601 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9661 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9721 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9781 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
     9841 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
     9901 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
     9961 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10021 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10081 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10141 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10201 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10261 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10321 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10381 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10441 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10501 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10561 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10621 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10681 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10741 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10801 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    10861 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    10921 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    10981 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11041 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11101 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11161 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11221 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11281 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11341 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11401 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11461 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11521 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11581 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11641 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11701 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11761 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    11821 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    11881 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    11941 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12001 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12061 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12121 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12181 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12241 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12301 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12361 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12421 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12481 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12541 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12601 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12661 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12721 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12781 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    12841 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    12901 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    12961 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13021 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13081 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13141 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13201 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13261 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13321 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13381 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13441 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13501 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13561 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13621 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13681 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13741 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13801 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    13861 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    13921 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    13981 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14041 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14101 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14161 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14221 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14281 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14341 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14401 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14461 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14521 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14581 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14641 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14701 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14761 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    14821 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    14881 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    14941 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15001 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15061 gaaatcaatc ttctacaaaa agctttagga atcctcgatt gggatacaca aacaggtatg
    15121 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15181 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15241 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15301 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15361 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15421 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15481 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15541 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15601 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15661 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15721 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15781 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    15841 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    15901 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    15961 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16021 ttttatcgtt tattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16081 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16141 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16201 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16261 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16321 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16381 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16441 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16501 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16561 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16621 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16681 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16741 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16801 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    16861 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    16921 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    16981 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17041 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17101 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17161 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17221 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17281 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17341 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17401 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17461 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17521 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17581 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17641 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17701 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17761 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    17821 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    17881 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    17941 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18001 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18061 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18121 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18181 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18241 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18301 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18361 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18421 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18481 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18541 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18601 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18661 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18721 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18781 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    18841 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    18901 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    18961 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19021 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19081 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19141 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19201 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19261 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    19321 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19381 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19441 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19501 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19561 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19621 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19681 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19741 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19801 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    19861 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    19921 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    19981 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20041 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20101 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20161 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20221 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20281 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20341 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20401 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20461 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20521 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20581 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20641 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20701 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20761 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    20821 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    20881 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    20941 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21001 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21061 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21121 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21181 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21241 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21301 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21361 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21421 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21481 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21541 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21601 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21661 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21721 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21781 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    21841 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    21901 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    21961 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22021 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22081 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22141 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22201 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22261 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22321 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22381 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22441 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22501 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22561 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22621 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22681 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22741 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22801 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    22861 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    22921 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    22981 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23041 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23101 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23161 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23221 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23281 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23341 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23401 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23461 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23521 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23581 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23641 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23701 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23761 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    23821 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    23881 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    23941 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24001 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24061 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24121 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24181 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24241 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24301 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24361 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24421 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24481 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24541 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24601 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24661 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24721 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24781 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    24841 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    24901 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    24961 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25021 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25081 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25141 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25201 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25261 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25321 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25381 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaatt aagtacgaaa
    25441 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25501 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25561 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25621 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25681 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25741 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25801 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    25861 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    25921 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    25981 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26041 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26101 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26161 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26221 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26281 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26341 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26401 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26461 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26521 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26581 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26641 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26701 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26761 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    26821 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    26881 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    26941 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27001 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27061 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27121 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27181 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27241 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27301 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27361 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27421 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27481 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27541 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27601 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27661 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27721 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27781 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    27841 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    27901 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    27961 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28021 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28081 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28141 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28201 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28261 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28321 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28381 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28441 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28501 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28561 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28621 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28681 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28741 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28801 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    28861 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    28921 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    28981 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29041 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29101 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29161 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29221 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29281 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29341 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29401 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29461 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29521 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29581 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29641 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29701 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29761 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    29821 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    29881 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    29941 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30001 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30061 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30121 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30181 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30241 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30301 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30361 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30421 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30481 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30541 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30601 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30661 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30721 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30781 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    30841 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    30901 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    30961 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31021 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31081 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31141 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31201 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31261 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31321 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31381 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31441 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31501 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31561 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31621 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31681 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31741 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31801 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    31861 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    31921 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    31981 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32041 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32101 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32161 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32221 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32281 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32341 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32401 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32461 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32521 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32581 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32641 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32701 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32761 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    32821 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    32881 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    32941 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33001 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33061 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33121 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33181 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33241 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33301 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33361 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33421 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33481 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33541 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33601 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33661 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33721 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33781 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    33841 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    33901 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    33961 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34021 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34081 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34141 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34201 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34261 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34321 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34381 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34441 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34501 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34561 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34621 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34681 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34741 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34801 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    34861 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    34921 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    34981 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35041 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35101 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35161 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35221 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35281 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35341 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35401 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35461 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35521 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35581 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35641 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35701 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35761 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    35821 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    35881 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    35941 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36001 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36061 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36121 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36181 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36241 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36301 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36361 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36421 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36481 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36541 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36601 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36661 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36721 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36781 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    36841 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    36901 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    36961 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37021 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37081 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37141 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37201 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37261 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37321 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37381 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37441 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37501 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37561 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37621 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37681 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37741 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37801 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    37861 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    37921 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    37981 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38041 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38101 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38161 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38221 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38281 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38341 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38401 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38461 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38521 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38581 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38641 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38701 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38761 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    38821 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    38881 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    38941 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39001 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39061 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39121 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39181 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39241 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39301 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39361 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39421 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39481 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39541 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39601 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39661 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39721 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39781 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    39841 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    39901 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    39961 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40021 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40081 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40141 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40201 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40261 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40321 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40381 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40441 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40501 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40561 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40621 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40681 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40741 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40801 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    40861 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    40921 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    40981 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41041 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41101 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41161 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41221 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41281 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41341 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41401 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41461 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41521 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41581 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41641 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41701 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41761 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    41821 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    41881 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    41941 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42001 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42061 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42121 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42181 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42241 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42301 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42361 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42421 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42481 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42541 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42601 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42661 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42721 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42781 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    42841 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    42901 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    42961 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43021 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43081 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43141 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43201 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43261 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43321 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43381 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43441 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43501 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43561 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43621 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43681 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43741 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43801 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    43861 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    43921 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    43981 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44041 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44101 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44161 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44221 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44281 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44341 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44401 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44461 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44521 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44581 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44641 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44701 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44761 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    44821 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    44881 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    44941 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45001 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45061 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45121 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45181 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45241 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45301 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45361 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45421 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45481 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45541 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45601 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45661 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45721 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45781 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    45841 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    45901 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    45961 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46021 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46081 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46141 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46201 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46261 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46321 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46381 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46441 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46501 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46561 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46621 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46681 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46741 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46801 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    46861 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    46921 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    46981 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47041 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47101 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47161 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47221 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47281 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47341 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47401 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47461 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47521 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47581 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47641 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47701 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47761 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    47821 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    47881 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    47941 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48001 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48061 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48121 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48181 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48241 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48301 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48361 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48421 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48481 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48541 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48601 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48661 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48721 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48781 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    48841 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    48901 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    48961 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49021 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49081 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49141 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49201 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49261 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49321 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49381 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49441 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49501 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49561 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49621 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49681 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49741 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49801 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    49861 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    49921 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    49981 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50041 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50101 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50161 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50221 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50281 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50341 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50401 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50461 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50521 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50581 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50641 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50701 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50761 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    50821 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    50881 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    50941 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51001 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51061 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51121 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51181 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51241 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51301 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51361 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51421 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51481 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51541 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51601 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51661 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51721 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51781 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    51841 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    51901 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    51961 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52021 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52081 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52141 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52201 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52261 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52321 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52381 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52441 ttttaggt
//
LOCUS       DAZKNV010000013        51604 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000013 DAZKNV010000000
VERSION     DAZKNV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.013"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            25..696
                     /locus_tag="ACG8M1_000862"
     CDS             25..696
                     /locus_tag="ACG8M1_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0421594.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="ACG8M1_000863"
     CDS             755..1195
                     /locus_tag="ACG8M1_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421595.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="ACG8M1_000864"
     CDS             1207..1875
                     /locus_tag="ACG8M1_000864"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFQ0421596.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="ACG8M1_000865"
     CDS             1939..2562
                     /locus_tag="ACG8M1_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFQ0421597.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="ACG8M1_000866"
     CDS             2618..3004
                     /locus_tag="ACG8M1_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFQ0421598.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="ACG8M1_000867"
     CDS             3217..4608
                     /locus_tag="ACG8M1_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFQ0421599.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5219..5587
                     /locus_tag="ACG8M1_000868"
     CDS             5219..5587
                     /locus_tag="ACG8M1_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFQ0421600.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5767..6708
                     /locus_tag="ACG8M1_000869"
     CDS             5767..6708
                     /locus_tag="ACG8M1_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFQ0421601.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6777..7508
                     /locus_tag="ACG8M1_000870"
     CDS             6777..7508
                     /locus_tag="ACG8M1_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0421602.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7652..9832
                     /locus_tag="ACG8M1_000871"
     CDS             7652..9832
                     /locus_tag="ACG8M1_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFQ0421603.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9852..10334
                     /locus_tag="ACG8M1_000872"
     CDS             9852..10334
                     /locus_tag="ACG8M1_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFQ0421604.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10350..11111
                     /locus_tag="ACG8M1_000873"
     CDS             10350..11111
                     /locus_tag="ACG8M1_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFQ0421605.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11242..12576
                     /gene="murC"
                     /locus_tag="ACG8M1_000874"
     CDS             11242..12576
                     /gene="murC"
                     /locus_tag="ACG8M1_000874"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFQ0421606.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12883..13368
                     /locus_tag="ACG8M1_000875"
     CDS             12883..13368
                     /locus_tag="ACG8M1_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFQ0421607.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13361..14044
                     /locus_tag="ACG8M1_000876"
     CDS             13361..14044
                     /locus_tag="ACG8M1_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFQ0421608.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14170..16815
                     /gene="polA"
                     /locus_tag="ACG8M1_000877"
     CDS             14170..16815
                     /gene="polA"
                     /locus_tag="ACG8M1_000877"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFQ0421609.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16860..17696
                     /gene="mutM"
                     /locus_tag="ACG8M1_000878"
     CDS             16860..17696
                     /gene="mutM"
                     /locus_tag="ACG8M1_000878"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFQ0421610.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17660..18289
                     /gene="coaE"
                     /locus_tag="ACG8M1_000879"
     CDS             17660..18289
                     /gene="coaE"
                     /locus_tag="ACG8M1_000879"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFQ0421611.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            18341..18673
                     /locus_tag="ACG8M1_000880"
     CDS             18341..18673
                     /locus_tag="ACG8M1_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFQ0421612.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18985..19476
                     /gene="nrdR"
                     /locus_tag="ACG8M1_000881"
     CDS             18985..19476
                     /gene="nrdR"
                     /locus_tag="ACG8M1_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFQ0421613.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19499..20872
                     /locus_tag="ACG8M1_000882"
     CDS             19499..20872
                     /locus_tag="ACG8M1_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFQ0421614.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20872..21798
                     /gene="dnaI"
                     /locus_tag="ACG8M1_000883"
     CDS             20872..21798
                     /gene="dnaI"
                     /locus_tag="ACG8M1_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFQ0421615.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21927..22367
                     /locus_tag="ACG8M1_000884"
     CDS             21927..22367
                     /locus_tag="ACG8M1_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFQ0421616.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22511..23212
                     /locus_tag="ACG8M1_000885"
     CDS             22511..23212
                     /locus_tag="ACG8M1_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFQ0421617.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23209..24330
                     /locus_tag="ACG8M1_000886"
     CDS             23209..24330
                     /locus_tag="ACG8M1_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFQ0421618.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24345..25577
                     /gene="pepT"
                     /locus_tag="ACG8M1_000887"
     CDS             24345..25577
                     /gene="pepT"
                     /locus_tag="ACG8M1_000887"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFQ0421619.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25709..26617
                     /locus_tag="ACG8M1_000888"
     CDS             25709..26617
                     /locus_tag="ACG8M1_000888"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0421620.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26652..26924
                     /locus_tag="ACG8M1_000889"
     CDS             26652..26924
                     /locus_tag="ACG8M1_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFQ0421621.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26935..27981
                     /locus_tag="ACG8M1_000890"
     CDS             26935..27981
                     /locus_tag="ACG8M1_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFQ0421622.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28232..30841
                     /gene="clpB"
                     /locus_tag="ACG8M1_000891"
     CDS             28232..30841
                     /gene="clpB"
                     /locus_tag="ACG8M1_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFQ0421623.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30992..31678)
                     /locus_tag="ACG8M1_000892"
     CDS             complement(30992..31678)
                     /locus_tag="ACG8M1_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421624.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31656..32150)
                     /locus_tag="ACG8M1_000893"
     CDS             complement(31656..32150)
                     /locus_tag="ACG8M1_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFQ0421625.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32170..33390)
                     /locus_tag="ACG8M1_000894"
     CDS             complement(32170..33390)
                     /locus_tag="ACG8M1_000894"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0421626.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33537..35372
                     /gene="lepA"
                     /locus_tag="ACG8M1_000895"
     CDS             33537..35372
                     /gene="lepA"
                     /locus_tag="ACG8M1_000895"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFQ0421627.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            35568..36479
                     /locus_tag="ACG8M1_000896"
     CDS             35568..36479
                     /locus_tag="ACG8M1_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421628.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            37475..37726
                     /locus_tag="ACG8M1_000897"
     CDS             37475..37726
                     /locus_tag="ACG8M1_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421629.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            37839..38081
                     /locus_tag="ACG8M1_000898"
                     /pseudo
     CDS             37839..38081
                     /locus_tag="ACG8M1_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            38171..38410
                     /locus_tag="ACG8M1_000899"
     CDS             38171..38410
                     /locus_tag="ACG8M1_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421630.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            38557..42840
                     /locus_tag="ACG8M1_000900"
     CDS             38557..42840
                     /locus_tag="ACG8M1_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFQ0421631.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            42939..43304
                     /locus_tag="ACG8M1_000901"
     CDS             42939..43304
                     /locus_tag="ACG8M1_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421632.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            43306..43758
                     /locus_tag="ACG8M1_000902"
     CDS             43306..43758
                     /locus_tag="ACG8M1_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421633.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            44207..45682
                     /locus_tag="ACG8M1_000903"
     CDS             44207..45682
                     /locus_tag="ACG8M1_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFQ0421634.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            45705..46016
                     /locus_tag="ACG8M1_000904"
     CDS             45705..46016
                     /locus_tag="ACG8M1_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421635.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            46377..47633
                     /locus_tag="ACG8M1_000905"
     CDS             46377..47633
                     /locus_tag="ACG8M1_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0421636.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            47630..48175
                     /locus_tag="ACG8M1_000906"
     CDS             47630..48175
                     /locus_tag="ACG8M1_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421637.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            48176..48676
                     /locus_tag="ACG8M1_000907"
     CDS             48176..48676
                     /locus_tag="ACG8M1_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421638.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            49035..49313
                     /locus_tag="ACG8M1_000908"
     CDS             49035..49313
                     /locus_tag="ACG8M1_000908"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421639.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVMQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            49333..49677
                     /locus_tag="ACG8M1_000909"
     CDS             49333..49677
                     /locus_tag="ACG8M1_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421640.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            49696..50607
                     /locus_tag="ACG8M1_000910"
     CDS             49696..50607
                     /locus_tag="ACG8M1_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0421641.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            50686..>51604
                     /locus_tag="ACG8M1_000911"
     CDS             50686..>51604
                     /locus_tag="ACG8M1_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0421642.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVIT"
BASE COUNT        17573 a         8597 c        11060 g        14374 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
     5221 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
     5281 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
     5341 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
     5401 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
     5461 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
     5521 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
     5581 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
     5641 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
     5701 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
     5761 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
     5821 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
     5881 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
     5941 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
     6001 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
     6061 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
     6121 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
     6181 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
     6241 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
     6301 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
     6361 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
     6421 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
     6481 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
     6541 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
     6601 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
     6661 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
     6721 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
     6781 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
     6841 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
     6901 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
     6961 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
     7021 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
     7081 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
     7141 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
     7201 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
     7261 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
     7321 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
     7381 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
     7441 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
     7501 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
     7561 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
     7621 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
     7681 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
     7741 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
     7801 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
     7861 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
     7921 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
     7981 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
     8041 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
     8101 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
     8161 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
     8221 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
     8281 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
     8341 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
     8401 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
     8461 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
     8521 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
     8581 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
     8641 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
     8701 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
     8761 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
     8821 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
     8881 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
     8941 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
     9001 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
     9061 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
     9121 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
     9181 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
     9241 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
     9301 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
     9361 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
     9421 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
     9481 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
     9541 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
     9601 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
     9661 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
     9721 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
     9781 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
     9841 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
     9901 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
     9961 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    10021 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    10081 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    10141 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    10201 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    10261 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    10321 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    10381 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    10441 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    10501 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    10561 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    10621 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    10681 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    10741 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    10801 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    10861 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    10921 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    10981 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    11041 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    11101 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    11161 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    11221 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    11281 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    11341 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    11401 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    11461 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    11521 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    11581 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    11641 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    11701 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    11761 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    11821 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    11881 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    11941 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    12001 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    12061 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    12121 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    12181 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    12241 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    12301 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    12361 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    12421 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    12481 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    12541 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    12601 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    12661 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    12721 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    12781 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    12841 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    12901 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    12961 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    13021 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    13081 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    13141 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    13201 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    13261 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    13321 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    13381 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    13441 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    13501 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    13561 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    13621 ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata ttggaacagt
    13681 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    13741 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    13801 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    13861 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    13921 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    13981 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    14041 ctaaaaaaga aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    14101 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    14161 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    14221 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    14281 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    14341 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    14401 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    14461 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    14521 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    14581 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    14641 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    14701 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    14761 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    14821 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    14881 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    14941 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    15001 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    15061 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    15121 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    15181 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    15241 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    15301 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    15361 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    15421 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    15481 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    15541 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    15601 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    15661 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    15721 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    15781 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    15841 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    15901 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    15961 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    16021 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    16081 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    16141 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    16201 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    16261 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    16321 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    16381 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    16441 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    16501 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    16561 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    16621 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    16681 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    16741 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    16801 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    16861 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    16921 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    16981 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    17041 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    17101 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    17161 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    17221 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    17281 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    17341 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    17401 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    17461 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    17521 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    17581 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    17641 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    17701 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    17761 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    17821 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    17881 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    17941 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    18001 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    18061 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    18121 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    18181 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaaa
    18241 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    18301 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    18361 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    18421 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    18481 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    18541 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    18601 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    18661 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    18721 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    18781 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    18841 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    18901 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    18961 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    19021 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    19081 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    19141 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    19201 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    19261 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    19321 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    19381 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    19441 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    19501 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    19561 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    19621 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    19681 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    19741 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    19801 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    19861 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    19921 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    19981 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    20041 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    20101 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    20161 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    20221 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    20281 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    20341 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    20401 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    20461 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    20521 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    20581 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    20641 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    20701 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    20761 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    20821 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    20881 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    20941 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    21001 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    21061 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    21121 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    21181 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    21241 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    21301 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    21361 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    21421 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    21481 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    21541 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    21601 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    21661 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    21721 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    21781 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    21841 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    21901 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    21961 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    22021 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    22081 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    22141 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    22201 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    22261 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    22321 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    22381 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    22441 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    22501 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    22561 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    22621 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    22681 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    22741 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    22801 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    22861 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    22921 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    22981 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    23041 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    23101 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    23161 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    23221 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    23281 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    23341 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    23401 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    23461 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    23521 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    23581 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    23641 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    23701 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    23761 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    23821 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    23881 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    23941 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    24001 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    24061 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    24121 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    24181 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    24241 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    24301 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    24361 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    24421 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    24481 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    24541 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    24601 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    24661 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    24721 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    24781 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    24841 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    24901 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    24961 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    25021 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    25081 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    25141 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    25201 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    25261 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    25321 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    25381 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    25441 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    25501 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    25561 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    25621 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    25681 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    25741 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    25801 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    25861 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    25921 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    25981 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    26041 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    26101 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    26161 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    26221 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    26281 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    26341 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    26401 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    26461 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    26521 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    26581 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    26641 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    26701 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    26761 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    26821 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    26881 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    26941 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    27001 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    27061 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    27121 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    27181 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    27241 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    27301 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    27361 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    27421 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    27481 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    27541 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    27601 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    27661 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    27721 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    27781 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    27841 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    27901 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    27961 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    28021 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    28081 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    28141 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    28201 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    28261 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    28321 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    28381 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    28441 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    28501 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    28561 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    28621 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    28681 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    28741 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    28801 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    28861 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    28921 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    28981 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    29041 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    29101 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    29161 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    29221 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    29281 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    29341 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    29401 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    29461 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    29521 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    29581 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    29641 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    29701 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    29761 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    29821 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    29881 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    29941 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    30001 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    30061 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    30121 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    30181 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    30241 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    30301 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    30361 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    30421 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    30481 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    30541 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    30601 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    30661 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    30721 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    30781 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    30841 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    30901 tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg aaatttcttg
    30961 aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt tctaatttat
    31021 aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat cccattaagg
    31081 cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct gctcgtccga
    31141 caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag aactggtcgc
    31201 ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca aagccgaata
    31261 agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag taaccaatca
    31321 atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt ttgtcccaaa
    31381 aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg aacaagaaaa
    31441 accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc aaaatgactt
    31501 gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg attccttgag
    31561 aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg aatacaccaa
    31621 aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt ccctccatct
    31681 aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt tccgttcaat
    31741 ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc tgtttcttgt
    31801 agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt atataagccg
    31861 atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc ggcatcgatc
    31921 gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc tgtgtcagca
    31981 agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc attttcttga
    32041 ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa ctgttggtta
    32101 tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat ctaaacatca
    32161 tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga tacgctctag
    32221 tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat aagaagcacg
    32281 gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg attttcctat
    32341 aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga agacaccatt
    32401 attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg ttccaacaaa
    32461 cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat atggttcgat
    32521 ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt tataaatatc
    32581 tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata agccatttcg
    32641 agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag ctacccagta
    32701 gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg tgcgctcatc
    32761 ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata aagcaccatg
    32821 gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa ctggtaatcg
    32881 ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga ttttaaagga
    32941 aagtttatca gacatgattt cccatccttt acgccgatag taggggatac tgtaaggata
    33001 caaataagag atccattgct tattcttgcg catattatcc aatgcaacga taattagatc
    33061 ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca caccacccat
    33121 tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt gagagatcag
    33181 tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt ttttggaacg
    33241 gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag tcacttggaa
    33301 cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg gttttaattc
    33361 aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta gcttgataac
    33421 agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa ctctttaaat
    33481 tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga gacgctatgg
    33541 atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc atcgctcata
    33601 tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac actgtgacgt
    33661 ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa cgtggaatca
    33721 cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa acatatatct
    33781 ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct cgaagccttg
    33841 ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa gcacaaacat
    33901 tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc atcaataaaa
    33961 tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac gtaatcggaa
    34021 tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt gaagatattc
    34081 tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca ccgctaaaag
    34141 ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat gtccggatca
    34201 cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc aaaacatttg
    34261 atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt ttgatggtcg
    34321 gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga gtaggggata
    34381 cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga aaaatgaatc
    34441 cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat ttgcgggaag
    34501 ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa acctctcaag
    34561 cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat gtcgtccaag
    34621 aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc gttatttacc
    34681 atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat tttcctgaac
    34741 ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg gtcccaaatg
    34801 attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc attacgatgg
    34861 attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct gaaattgtct
    34921 ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg gattatgaaa
    34981 tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat ggagaaaaag
    35041 tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga aaagcaatcg
    35101 ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc caagcagcta
    35161 ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac gtcttggcta
    35221 aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa aaagaaggga
    35281 agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc atggccgttc
    35341 tgaaaatgga tgagcaagat agtgtgaaat aacttataat caatcgaaaa acctattaaa
    35401 taaacctttt tgagtagatg caacactgag gattatctgt ataaaagatt ttaaactgtc
    35461 atttggttat cacggcgata ctaaaattaa caaaattgga atatttttct tgaagatttt
    35521 tagctgtcag tatatgatga aagcatctca taggaggtgc ttttttcatg gttgataatt
    35581 caagtggaag ggttcttaaa tctctaagaa aagagaaaaa actatctcaa aaaaagttag
    35641 ctgatttagc aggtatttca caaagtactt tagttaaata tgaaaaaggg tcaagaaaaa
    35701 tccctaaaga cgtagataat actctaagca agattctgaa tatagaaact ctaataaaag
    35761 atgaggaaga taagattgag attctcatcg gtaaactaat tgcatacaga gatatgaata
    35821 agttacttaa caaagagtta gctgataata taggaattag tgaagtatta ctcagttatg
    35881 tgttaaatag aaagagaaat ccgtcaaaag aaatgcaaaa aaaaatcgat atttttctat
    35941 taagtaatga aaaagaaatt ttgaaggaga ttaatcgtga tagtgagata tttagtttat
    36001 caaaagacga taaaattgtt atgggaaaaa gaatacgaga agtccgaaag aaccgggaag
    36061 agacgcttga aaaatttggt aaaaacttta ccatctatac aggcaaaaat gttataagta
    36121 gatgggaaaa aggtattaat attccagata ttgaaaaact aatgaatatt gcctatcttg
    36181 gtaaggtcac tgttccttac cttatgtacg gagaagatta taagaatata cttccaaaag
    36241 atgaaagagt tagcgatttt aaaaagataa attcttttag tatgggatta aggatgagga
    36301 aaattaggaa agattattat ctagaaaggg aggagtttgg aaagcttttt tctccttcaa
    36361 tttcaaaatg gtccatagat aggtatgaga atggtagaga tatacccaat actaatcgaa
    36421 ttatccaata tgcttatata ggaaatcttt ctttagaatt tttgatttac gggatataaa
    36481 aatagtttac gtcgatactt attaagttat cgacgttttt tattatagaa aaaatttata
    36541 aaaggaggtt tcttgatatg ataagaaaca aaaagggttt gttgaaagtt gctttactgg
    36601 cagctttttt ctaagtaact ttttgacaag ctcaatggca acacaagcgg aagaagtaat
    36661 acaagaacta actgttatga ataacagcta gataaaatgg gctatgtatg ttatccaaca
    36721 atttagtaat cactagaagc ctagcgaaag ttcgcttgat aagttataga tgagtattga
    36781 tttgtagtgt ttccaaatca aaagggtaca gagccacatg aaatatgttg tcctctgcag
    36841 cgtcaggatg ggaatccata ccatggagat tcggagatct gtgagggaat acttacgtgg
    36901 ttaatatgtc agttgtgttg gacgtagtaa tggtcatagt gggtagattg actgaattct
    36961 tatatgagaa aatgaaacca acaagaagat agggttattt atacagaatt ggggatcttt
    37021 tctggaaaag taatcggata atgcgagatt cgtacggtct tttttaaatt tctctaaaaa
    37081 aaacggcatc gaatgggttg ggtgattgat aagcaatgaa tcatagactg atatagaata
    37141 aaaaatgatt ctatttatct ttttacatct atcgtttttt caagtagccg caaattatat
    37201 cagcattcaa caatttttgt atacaagttc tagtaaaagg atctgaagaa aaagttggtt
    37261 gttgtgaaga taaaaaaaga atcaggtttt actgagtttt tcttcaaaat ttgtgttatt
    37321 aggttaggac aaagataaga agaagtatga agatttaaaa aaggaatgag gaaaagatag
    37381 taatttccga ttattggagt ttttttattt ataaagaaga agcgaataag ttgtgattcc
    37441 tagatttcgc gcgtgattaa ttaatgagca aaaaatgcgg aaagttttag tgtttaatac
    37501 acgaggacaa agtttcttag gtattgaagg cacacgtgta acggttgatg ggtggtgtga
    37561 ttgtttcgag gttggaaaac atgttgaact tatggcattt actgagctaa aagataagaa
    37621 caacgtggaa tttttcgaga gtgatattgg ttgggacgat catgaagaag tttatggaaa
    37681 atttattttg cggaagggaa attcttatac gaatggggaa gcataagtag cgatttgtta
    37741 gagatcattg ataggattga aattgtcggg aatatttatg agaatctaga gttatttgag
    37801 gtgatagaat gagtgatggt tttgaacaag tatcaataat taaaaatcaa gttcgggaga
    37861 ttcttagaaa aaaaggctat ttggtagata gttattttga aggagattac gaaacatggg
    37921 taggtgtcta tgctcgtcca gagaataaac ctacctattt agatcctacg acgtcagaag
    37981 atgcctattt acaaaatagg tatcgagtag atggttttaa gcaagacttt gcggagtggt
    38041 ttgaatggga aattgaaaac ggagaagtaa aagaagaata agagtacttg ttgtatcaaa
    38101 ataagccagt agaacaacca aaccagtagc tagtaatgac aataatactg aggaatcgga
    38161 tcattatggt atgattgata tttctcttcc agaagatctt aagccagatc ctgtaacaat
    38221 tggcaatagt gtcatgattt ttgattcatt agatgaagct atgtcatatg gttggaaaga
    38281 aattaaggat gaaggtagta attggtatgg catgagattt ggtgatggtg aagttgccaa
    38341 aaaagctggt attccaattg ggaaatggac agttgatttc cacgaagcag gttctttttt
    38401 tgttctgtaa ttatagtggg agggtaaaat cattgatgaa atgtgttcag ataagagcgc
    38461 cagataaaaa tagaagagac agttcacgtc gttatcactt ttggtaacgg cgttttgttt
    38521 tattatataa aattctcagg aaaaggagga attcttgtgt atgcaaaaac gaaaatgaat
    38581 tggttgaaag cactcgcatt ggtggctttt tctcaattct gtttcttggt gggaactgct
    38641 caagcacatg cagaagaaac gacggctata caacctacga tggaagccat tgcccaagtc
    38701 gcttctgaag tgacagaagt ccaaccagca gaagccgggg tcccagctgg tgaagccact
    38761 gttgaacagg cccctgtgac agaagcgcca acggtcaatt ccaaaacgac tctcgatcag
    38821 acgattgggg aaacacaaca cccagggaat agtcctggta cttcacaacc agttgaagaa
    38881 actgcctcaa ttacaacccc tgcttcagaa acgtccactc tagaaggaga aaaagctgcc
    38941 gaagcaacgc cttctgtgca gccagagtct tctgagaaac aagcggaaga aaagaaacga
    39001 atagaagaaa cagtggaaca accagcggct actgctgaca aagaaggaaa aaatgaggaa
    39061 aacgttgaaa aaacaatctc ttcaaccgca gctagtcaaa atcaaccaac gaaaccaaac
    39121 aaagaatcta cggctagtat tgaaaatcaa aagaaaaaag agcagaacat tccaaaaaca
    39181 ggtacaccta cactgttagt aacagtacca accaatcgtt cggttcgtgt tcgccgtgca
    39241 accaatgcag ctgttttagg tggtcggaaa attgattggg gcgaaaatat tggtgttact
    39301 tctagtccga acaatctaaa cttcacttta aattatatgg ttcgttttga gattaatgga
    39361 caagtggcgt tttgtattga gcctggtgtc tcagccgcag aaggtcaagt ttatacagct
    39421 actgctttga aaaactattt gaaaaattca aatgtacgga aaaaaacaag cttgatctct
    39481 tatttaggat atgtcacaaa taaagacaaa tccgatgaac aatacattgc ggcacaattt
    39541 atgatttggg aagctttggg cacaaaaatc ccaatcaaaa atatccgtgt tgattatgat
    39601 cgtcgaaaag cagaaattca acgtttgatt aataactttg gtgaaaaagc aacttttaat
    39661 aatcaaacac atacggtaaa aattggcgaa acgttgaaag taaagaataa aaatgatttt
    39721 ttgaaatatg tgaaagacat tcaaaaacca aaaggtgtca atgtatctat tcacggcaat
    39781 gaagtatgga ttacagtcac aaaagaggca ccggataaag caaaaattca attgaataaa
    39841 attaaagttc aaggtgcgcc attagcctat cgtcgtccag gagctcaaac aattggtgtg
    39901 ttacatccaa cagaacctaa tgcgtctgtt attaatttac aaattctaaa acaaggaaac
    39961 attcgtgtgt ttaaagaaga tgcggaaact ggtgtgaaag cacaaggtgc agcttcttta
    40021 gaaaatgcgg tctatggttt gtatcaagca gatgggaaaa agattaaaga aattaccttg
    40081 aaaaaaatta acggcaaagt acaggcagaa attaaagatc ttgatcctgg caaatatgtt
    40141 ttaaaagaaa tcaaagcgcc aaaaggttat gtgctttctg atgaagcaat tgaaattgtt
    40201 gttgaacctg gaaaaactgt caatgcgacc gcaaaagatc aagtgatcaa aggaaccatt
    40261 gatttagtga aagttgctaa taaagattta gtcgattcaa cgaatccaga taacaaacca
    40321 aaattagctg gcattgaaat cactttgacg tcaaaaacaa ctggcaaagt ggtgaaaacc
    40381 gttgtgacag acaatgatgg ttatgctact tttggtaaaa ataccgttgt ctttgatacg
    40441 tacattcttt ctgaaaccaa aggaaaagaa gggtataaac tatttgaacc acttgaagtc
    40501 acaatttctg aaaatgggca aactttccat tatgttttag aagataaagt aattgaacaa
    40561 cgtcttaaag tggtgaaagt ggatcaagaa acaggaaaag tgattccact tgctaataca
    40621 gaattcaaga tttttgatac tttagccaat cgttatgtca caatggagat tccaaatgat
    40681 acagaaacaa cggatatctt taaaaccaat gaaaaaggct ttttcctaac taacggtaca
    40741 cttacttatg gaaaagatcg ctatcgtttg gaagaaatca aagcccccgt aaattacgtt
    40801 ttgaatcaaa acccattagt gttctcgatt accaatgata cagaaccgat caaagtgatc
    40861 cattttgcga accgtcaagc acggaaaagt gtaaaattat tcaagtatga agaatggaac
    40921 aagaagaaaa cgccgctcgc aggtgtgaac tttaccttgt ataacggtaa aaatcaagca
    40981 attggtgaat ataccactga tcaaaacggg gaaattttag tgaaaggtct agttgccgat
    41041 gactattact tcttggaaaa tgccccatta gaaagtttcc aaccaaatac agataaacaa
    41101 gcattcacgg ttgcattcaa acaaaatgcg ccagatgatg gggaaacgtt agtggtttct
    41161 gtacgtaatt acttgattcc accaaaacta gaaacacaag cgtcaaataa agccgatggt
    41221 gaaaaagtgg ttgatccatt agaaacgatc gtcattaaag acagtgtttc ttataccaac
    41281 ttgtttgtcg gaaaagaata caccatttca ggagtattga tgaacaaggc aacgaatgcg
    41341 ccaattttac aagatggcaa agaaatcaca agtaccttgg cctttattgc agacaaagtc
    41401 aatggcacaa aagaccttga atttgtggtt aatgctagtg ttctgaaagg tcaaacgatc
    41461 gttgtttttg aaaaactttt ccgtgatggc attgaagttg cagcacatgc ggatatcaac
    41521 gatgaagccc aaagtgtgaa agtgaataat ccaaccgttc ataccacggc tgtctttgaa
    41581 gacggattga cagtcgcaga cccaacagga ttgtttacct taaacgatac cgttgaaatt
    41641 accgagattc ttccaggaaa agcatacttg gtcaaaggga tcttaatgga taaagcaacc
    41701 ggtgaaccct tgcttgtgca tggaaatacg gtagaaacga gtgttggctt tattgccaaa
    41761 gcagaaaatg aaacggtgat cgtaccattt acctttgatt tgacaggtat aaatggtcgt
    41821 gaaatcgtcg tgtttgaaag tctttttaga aatgatgaag aactagcaaa ccataaagac
    41881 atcaacgaca aagggcaaac ggtacgagta actaacccaa gtgtacgtac aacggctaca
    41941 cataaaccca ctggcttgaa agaggttaat ccattaacga aagtcaccat tacagacgct
    42001 gtgaaatacc acgatttggt cgttggaaaa acatacacag tcaacggtgt tctaatggac
    42061 aaagtaacgg aaaaaccagt gctagtagat ggaaaagaag tcacaagtac cttaacgttt
    42121 gtggcagaaa caacggatgg tacagtcaat ctagacttta ttctagacgc acgtgcgttg
    42181 cgaggcaaag aagtcgtggt ctttgaagat ctgtttagag aaggcgtatt attggcttct
    42241 cacgcagata ttaccgacaa tgaccaaacc atcaaaatca gtaatccaac cattacgacg
    42301 aaagcgacga ataaaaatgg cggaaaagag atcttggcct tgccaaatca aactgtgctt
    42361 gaatgggtca aagtagacgg tcttgcgatt ggtcaaatct atcgcttaat tgttcaaggc
    42421 tacttaacac cagacggcac accatttgaa ggcactcatg cggaaaaagt ctttgcggcc
    42481 gataaagaaa tgatggaatt cttatttgaa ttcttagtgg acggtcgcaa tcttgcagga
    42541 aaaggcttga gttttgcgga atggctccaa gcgaaaacgg aagatgagaa agaaacgttt
    42601 gaagaagtgg cgaaacacaa tgtagatcta acaaacaaag atcaaacggt tcaaattgtg
    42661 gaagcgccaa aaccaccgca accagtgaaa ccagaacaac gggttaaacc agctactgtt
    42721 gtaccaatgt tgccaaaaac aggtgaacaa acaagtagta tacttatggt tcttggatta
    42781 gtagtattag tcattgcttt aggtataaca ctttataaag tacgtaaagc caaagattag
    42841 tcatgaggaa caagcggtta ggatttttaa ccgcttgttt gattgtaatg tagaaatatt
    42901 tagaatttat tttggttttt aagaggagga aaaactttat ggcagaaaaa gcattgcgta
    42961 tgaagaaaga gtttttaggt caagtatttt tattgggttc acgggaacct aatccaccaa
    43021 aggaaattaa tggtgtgtct gggcgatatg ttcaattaca agcagagtgt tcgcgagaag
    43081 aacagcctgc tttttttgtt tatctcacag ctgaagagga taaaagatta cgattaccag
    43141 aaaaagaggt gcgtatttca tttgaagaag cttattttgt ttttcgtaaa gaacgagtga
    43201 atagtcgtga aacaaatgat atgggacaaa cagagcgtcg aacaactggc tatcaagatg
    43261 ttggtgtctt tttaactggt gtaaaaattg gggaggtttt gtaagatggg attaaaattt
    43321 ccaaataatt atgacattac agaagcatta gatgaaactt gtttaggagc cgtacgcttt
    43381 ggcgcattag aagagtctga tcgtgtattt gataatgaaa caggcgatta tacgggagaa
    43441 attcgatcac agcgagcaca attagttttt ggaaatccag atgaaccaaa gattgcacga
    43501 cgagttaaat ttccagcaga tgtagatttg actggtttta aacgacgtga tcctgtgaaa
    43561 ttaattgatc cagaatatca tgtggtatat attccagcac aagatggcaa tcgtgaatat
    43621 tcagatttag tgatttatgc gaaaggatta gagaaagtag aagctccaac aaataatcct
    43681 aatatgaaac aatcacaaga aaaaggttta gatcaaaaac aaccaagtgt tgattctaag
    43741 gaaaaagaga aaaaataagg tttttttgaa agaataggaa ggagtcttcc tattcttttt
    43801 atctaagata gaaggaaggg gagattttga attcagataa aaccaatcaa atactttgag
    43861 agattgtgct tgttatcaaa atatccaaca attgattgag tattttggag acaatccaac
    43921 gatttttgta caaacaaatg catatatttg tgcggttatt gggcagtgta tgtttttacg
    43981 tgatcttgtt cgtttttcat taccgtacca gtggaaacaa gatcatcagg aagtgatttg
    44041 gattcgtata gtacgaatat gtaatatgtg tgcacaccct tataaaaatc gattaaatct
    44101 ttttcgatta tgttttttta ctaaatgtga tattcctgta ttagttgctt tttgtcaaaa
    44161 gtttttagca caggaaaagt aaaaacagaa aggaggaatg tgacaattga aagctcattt
    44221 tttcaagtat cgtggtcggc gaattcgcta tttcaatcgt tatttatggt tttgctatta
    44281 tggtttcttt ttgtttccat ttttgattct gttaggttgg tttagttgga aagtatttta
    44341 tccacgttta agtacgtttt cgaattggca aatgtatctt attcctggaa taagtattgt
    44401 gttgtatttg ttgctggtta gtgggttaat tttagggttg atgcattggt cgcgactaaa
    44461 agaaggatat tttgcctctg tttattggcg tcagttactt gttcgaatgt taattgacaa
    44521 tcggtttgtt tatacaaaga aacaagttag tgagaaacaa acaagggaaa aaatgagatt
    44581 accaaaagtt tatttttatc aaaagaaaca agaattagtg gtttcttttc ctttagatgg
    44641 tgggcgtttt cacgaacgat ttttaaaaat gggtcatttg ttatctgaag tatttttgcg
    44701 tgatttaatt cgtgaagaac gagaaaaagc ccgaatcaat tatgtattcc tttcagattc
    44761 tggtcggatt cctattgatc aatgtatagc agaaaatgga cgtattcatt taatgaaaac
    44821 tttggattgg gtatatgatc aatcaccaaa tatgttgatt gctggtgcaa tcggtggtgg
    44881 gaaaacctat ttattgtatt ctttaattca agcttgttta agtgttggga cagtagatat
    44941 ttgcgatgga aaagcggcag atttagcagc attaggtgac gtcgatgtat tcaaaggaca
    45001 tgtgttttac aaaataaatg aagaaatgat tatttgttta cgaaatgcat taaaagaaat
    45061 gaatcaacgg tatgcctata tgaaaaccat gaaagatcct aaatatgaac cagggaaaaa
    45121 ttatgcttat tatgggttac caccgcattt tatctttttt gatgaatggg cagcttttta
    45181 tggttcgttg gatatggaag cgagaaatag agtcgataaa ttgattcagc cattagtatt
    45241 aaagggtcgt caagcaggga tgtacattat tttagcaatg caacgaccag atgcagaata
    45301 ttttccaagt ggtgttcggg ataatttaac attccgtatt tctgttggtc gattgtctcc
    45361 cattggttat ttaatgactt ttggagaaga ttttaaaaat aagccatttt acaacaaaga
    45421 tcaacctggt cgtggatatg cttttccagg atttgatgta cctgtagagt tttttgcgcc
    45481 atttgtttac aaagattatc actttatcaa agaatttgag aaatttactg aaatgattgt
    45541 ctatgatttt acagtaaaag aggatagtca agatcaaacg atgggagatg ataatcagtt
    45601 gttacaagaa caactagagc gccaaatgta tttagcaaaa gatccaaaag gaacaagttt
    45661 ttctgatgcg catattttgt aatcaactaa ggaggtgaag ttaaatggca gagagttgtt
    45721 attatagagt agctacagca atacgaatga ttaatccttc tctttcttcc agaacgtttt
    45781 atgattggtt gaatcgtatt gaacaagtaa ctgattaccg ctttttgcgc aaagaacgtg
    45841 tttttacagg aaaagttatt aatcaagtat tgctaacgaa aaaagatata gaacgattga
    45901 ctcgattgta tcattatcga gtagatttag aagaggattt aactttgtca atttatcgcg
    45961 ttttttctcc tgaaaaatat agtgaaataa caaaattaga tcatttaatt ttgtagttat
    46021 tatctatcgg gagggctcta gacgtagtct ggtagccgca ctctgcctgg cggtgcgcat
    46081 taaggctgcg aagcatgggc ctataatgcg cactcgctag cagcgtgtgc agctcacaaa
    46141 gaggtcgtgc gcttgcgcac ggcctctttg tgtaaagccc cccgatatat aatatggggg
    46201 gcagaaataa cataacacat agaaaaaagt tttataaacc cttttgtatc aagtgattat
    46261 ctaaggtcag cagttgtact acttttccca aaaaacgagg gggactagtt gatatatcgg
    46321 tgtttctaaa gggttaaaaa aaatcgattt tgttatttta taaaaggagc gagaaaatga
    46381 caccgattga gctaaaaagc tacagaaaga agttaagtgc aattcataat ataagtggag
    46441 ataaaaagcc gctatcacaa gcaagatttg cgcaattgat gggctgctca aaagattaca
    46501 ttagaaagat ggaacaaggg aaaagaaaaa tcccagagga ttttgaacaa cgaatcaagg
    46561 aacgctttcg attgtatatg aaaagcggaa tagatcttcg agcaatgatt gattatttgc
    46621 gtctttcctt ttttgggaca gactacaaaa cagtgattca acgtgtatta cgaatggatc
    46681 tgacagaatt tgaaacacgt ccaacgggct tgtatctttt tgactgtctt tctgttcgtg
    46741 ggaatatctg ggtgttctgg cattcaaaac gaactgtaac agaaaatgta cttgtgcaat
    46801 tttcaggaca aggttgccgg gaatatgagg aagtcatgcg tgaacaacaa acagattggc
    46861 gaacatggct atattccatt tggaaaaatc aaggaaagtt ggaagctggt tatacacgtg
    46921 tgcaatgtag ccgattcgat attgcgttag atgaactttg gggattggaa acggaagaac
    46981 atttcgatct ctttgaatta ctagaaaaac aaaaagcagg tttattagaa atggacttta
    47041 agagattcca gaatattggc ggttgttttt tagatgatgg ctattttcga agtgaaggat
    47101 tatctttgta ttttggatcg cgaaagagtc ctctcttttt taatttttat gagaaacgtt
    47161 ttgaaattgc gaaccgagaa aaaatttcag aattagaagc attaacgaaa tatggtattt
    47221 ataatcgata tgagttacgg ttagccaatg agaaagcaac acaagcagta gaagcattta
    47281 ttttaggtga ttcaccgaaa cgtttaggag agattggcgt tggtttaatt aatgcaaaac
    47341 ttattgtttg ggatagactg gaaagtgatg cacggattgt tgataaacga tgggcaaaat
    47401 tatttcgttc gatggaagaa ttggatttta cagtaaagcc agaaaaattc tcattagatc
    47461 gttcagaacg ctggtttttg aaacaagtag ctccgacatt aaagttgtta caagaagcag
    47521 atcgtatttt aggaagagac tttgtacaag aagggattga taatgccgaa ctaaatgacg
    47581 agcaacaaaa ctatctagaa tggatgggaa cgtcaggagg gaaaattgca tgaatgcata
    47641 tacgacaaca gaatggctgc gcctgttgga tttaaaggct gcaatcgaag cattaaatga
    47701 aaagatggtt gatttgtctt attttcgttt tcgagttcct tatattgaac aagcggtaaa
    47761 agctggacgt tatcaggaaa aagagaactg gcaagaaatt gcacgcttat tagaagttcg
    47821 taagggatac gaacaagaac tcgaagagtt ggaatttagc cgaaggaaag gaaggctaga
    47881 attcattcgc ttttatcgat tttcattgcc aatacctgcg attttagcgg ttaaaaaagg
    47941 ctgcgataaa atgaagatat atgaaaactg tgtggcagca cttagcagcg aaaaacctct
    48001 tatggaagaa atttcattgg tgactgtcac ttgggaaatg agtcgccagc caacagaaga
    48061 acagacatat ctttctttag aagagattga gatagaatta gaggaaattg gtcgctatgc
    48121 cacttgttct acctattgtg gatcggtcat tagtattgct ggtgtgattg tctaaatgaa
    48181 aaaaattatg atttatgttg gtgcgtattg gtcacgtgat ccaacagtat tagaaaatcc
    48241 agaggcggta cactattgct tgcgccaatt attctatctg tataaagaac gattagaatc
    48301 gttgattcgt cagttaccat atactgacag acgtttagat gaacttcttc taaggtatcc
    48361 agcaatgtat aaacgacgaa aaaatagatt gttaccagaa gagtatccca ttgaaaaaca
    48421 tgaacttgaa gggcgatttg tggcttattt ctatgatgat gttcgtatgc gcttagtaga
    48481 acaacgaatg gaaatagaaa atgatcgcta ctattttatc aattattgta agaagcgtaa
    48541 gtatcaagta actgatgatt tttatgattg tattttacaa gatggggaag tgattctatc
    48601 caaaattgct ccaagttttc gtgaacttgt gccgattgat tttttgaaaa aatgtcattt
    48661 gcggattctt ccgtaaaaaa gagctataaa aggaaagaaa agtagaagcc aaatcggttt
    48721 ctgctttttt atttttttta ggaaggagaa gatggtatgt cactggaatt tttaggagag
    48781 ccaattgaaa aggaagagtt cgtttcgcat tatatggatt tgtttattca ggtgataaaa
    48841 aactttgtgc gattgatgaa ttttatccac gcgaacaaga ctatctagcc gctgaacgaa
    48901 taaaaatcag tttattatgg gaaaaattca cagatgaaaa taaccgaccg ccagattatc
    48961 gctatttatc agattgttta acgaataatg tgctttctaa agaataccta tttcacaaac
    49021 gtgagaaaaa tcaaatgtcg gttgaacatt tttgtgattg ttatattgca ttattgcgta
    49081 gtcaacagtt attaacagta gaacgatatg gtgcagagtt tggttatgtc atgcaagctg
    49141 agcgtcatag agctacaaga tgctatgaaa aagaagatca agtgattgat ggctatgaag
    49201 aattatgtat tcgaaacaat cgctatttgc aacaacgttt atatgaacaa ttgatgatgg
    49261 atttttcaaa tctctataga gggtatgaat gttcgatgat tcaagaaagg tagaagaaaa
    49321 gggggaattt ttatgtggcg attattattt ttggtggtat gtggtatggc attgttctat
    49381 gtgtatcgtg tctatctcta tccacgaatg gaacgatgga caagttggta tagagatcct
    49441 ttaaaacaac gaaaaggatt gaagcggtat cgttatgaat tacttgttga attttcggat
    49501 gggcgacaag cacagtatta tttttttgca aactatccaa aatacaacac cagtgaacta
    49561 ttgattcaat tattcaaaaa taatccatat gttgggttag aagaaaacgg acgggagttc
    49621 ttttatcgtt cagataatat tagtgcggcg tctatgaaca aaacacgaat tgcataaaaa
    49681 attggaggaa taatcatgaa aaaaacaaca ttagcagtcg taacaacact aggaatttca
    49741 ttattttcgt ttcaattagg gagttcattg gtttatgcag atgaaactgt agaaacacct
    49801 aagtcagaaa ttgtagaaac attgccaggg gaaggattac cagatgttga gacagagcta
    49861 aatggaggaa caacggaaaa accagcagaa cctgaacaat tgcagtcaga gaaacctgaa
    49921 aaagagccag tgacaccaga accagagttt cctgaatcaa ctttaccgac tgattcgatc
    49981 gaagaagaag gtgtgcatag ttcaacaaca acggattcaa gtatagtcac aactccggaa
    50041 caatcaggaa caaccagttc ttctgaaaag aatactgatt cgtcaagtac ggaacagcca
    50101 acgatgtcgt ctaccagtga agaacaaaaa gaagaaccga aacaacctgt tgaaaaatca
    50161 gaagcaattc caaaagaaaa taaacctatt gttccagcaa aagaagtcac agtatcggta
    50221 accccaagcg gtgaaattac gacgaatact tctcaaggaa tgagtgtacc gattgtcact
    50281 agtaatgtag aggaattgac ccatattcca acaccaacca ccccattaaa agtagcaggt
    50341 gatcaaacaa ttgttggtgt aaaagatggt attccattaa tccaagatag tgaagggaat
    50401 ttggtaaagg atttgtcgat tcctgtaaag aaacttccaa gtggcaatat tgaaatcaaa
    50461 acagcagatg gaaaaacaaa agtcttacca aagactggtg aagaaataca tgttgcactt
    50521 tctgttctag gaggagtgtt gacaagtatt gctggatttg ttggatataa aagaaagaga
    50581 aaaggaatag aaaatgaggg taattgaatg gactattttt cagaaaaaca agcttatcgt
    50641 tgtcaatcgt acgtactagt aaaaacatac tagaaggagt agcttatgaa aaaacgacaa
    50701 ctacggcgga aagaaaaagt ttatacagag aaagtaccga agcaaaagaa aatccattca
    50761 aaaaaagcag tgaaatggat ttggtgtttg gttttatttc tttgtttttc agggggcttg
    50821 gcattttttc aatccatgaa aacgaaggtt caagtgtcgt ttttgaaaga tgaaatccaa
    50881 caattacaaa agaaagaagt acaaagtcgg tcagaattaa cgtacacacc tgaaattgaa
    50941 tcctttatga atcgttttgt tgctttgtat atgaatacat tcgataatca tgaacaagaa
    51001 caacaacgtc aagaaacatt aaaaaaagag ttttatgcac aaaactttat tcaagaacca
    51061 ggaagtgttt caggtgttcg aaaattaact gctgcttcgt ttattggatt aaaagaaatt
    51121 gaaaccattc caactgctag ttataaagta acttatgata ttcgctcgat gaatccagag
    51181 agtaagaaag aaacaagtgt gacaatcaca caagtactca atcttccctt ttctatttca
    51241 aacaagggct gtcgtattat tgcttatcct tattttacgg cactaccaaa gaatacagaa
    51301 aaacaacgaa tgattactta tgatgacaca ttatacgaaa cggttgatgc gtcggaagcg
    51361 aaagatgttg aaggatttgt ggaagatttc ttagataagt atgcgaaaaa caatgcaaaa
    51421 gatatgtcat acatgatgaa agaacctgaa ggactcaatc aaacagctaa agttgatcaa
    51481 gtagagatga aagtattgcg ttataaagaa acgaaaaaac cttttattgt aaaagcaacg
    51541 gtcgtctttc gagatggtga tacgtcactt ttacaaaaag aacaaatgac gattgtcatt
    51601 acga
//
LOCUS       DAZKNV010000014        51300 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000014 DAZKNV010000000
VERSION     DAZKNV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.014"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            330..1175
                     /locus_tag="ACG8M1_000912"
     CDS             330..1175
                     /locus_tag="ACG8M1_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0421643.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="ACG8M1_000913"
     CDS             1456..2676
                     /locus_tag="ACG8M1_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFQ0421644.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="ACG8M1_000914"
     CDS             2673..5393
                     /locus_tag="ACG8M1_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0421645.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="ACG8M1_000915"
     CDS             5377..6321
                     /locus_tag="ACG8M1_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0421646.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="ACG8M1_000916"
     CDS             complement(6390..7400)
                     /locus_tag="ACG8M1_000916"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0421647.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="ACG8M1_000917"
     CDS             complement(7580..7924)
                     /locus_tag="ACG8M1_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFQ0421648.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="ACG8M1_000918"
     CDS             complement(7917..8351)
                     /locus_tag="ACG8M1_000918"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFQ0421649.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="ACG8M1_000919"
     CDS             8489..9226
                     /locus_tag="ACG8M1_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421650.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="ACG8M1_000920"
     CDS             9219..10430
                     /locus_tag="ACG8M1_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421651.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="ACG8M1_000921"
     CDS             10634..11416
                     /locus_tag="ACG8M1_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFQ0421652.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="ACG8M1_000922"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="ACG8M1_000922"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFQ0421653.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ACG8M1_000923"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ACG8M1_000923"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFQ0421654.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="comGA"
                     /locus_tag="ACG8M1_000924"
     CDS             14132..15061
                     /gene="comGA"
                     /locus_tag="ACG8M1_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFQ0421655.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /gene="comGB"
                     /locus_tag="ACG8M1_000925"
     CDS             15018..16067
                     /gene="comGB"
                     /locus_tag="ACG8M1_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFQ0421656.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /gene="comGC"
                     /locus_tag="ACG8M1_000926"
     CDS             16064..16342
                     /gene="comGC"
                     /locus_tag="ACG8M1_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFQ0421657.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /gene="comGD"
                     /locus_tag="ACG8M1_000927"
     CDS             16317..16787
                     /gene="comGD"
                     /locus_tag="ACG8M1_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFQ0421658.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16759..17106
                     /locus_tag="ACG8M1_000928"
     CDS             16759..17106
                     /locus_tag="ACG8M1_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421659.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17069..17494
                     /gene="comGF"
                     /locus_tag="ACG8M1_000929"
     CDS             17069..17494
                     /gene="comGF"
                     /locus_tag="ACG8M1_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFQ0421660.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /gene="comGG"
                     /locus_tag="ACG8M1_000930"
     CDS             17466..17825
                     /gene="comGG"
                     /locus_tag="ACG8M1_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFQ0421661.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="ACG8M1_000931"
     CDS             17997..19004
                     /locus_tag="ACG8M1_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0421662.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="ACG8M1_000932"
     CDS             19029..20213
                     /locus_tag="ACG8M1_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFQ0421663.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /gene="abc-f"
                     /locus_tag="ACG8M1_000933"
     CDS             complement(20650..22233)
                     /gene="abc-f"
                     /locus_tag="ACG8M1_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFQ0421664.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22338..22466)
                     /locus_tag="ACG8M1_000934"
     CDS             complement(22338..22466)
                     /locus_tag="ACG8M1_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421665.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22811..22954)
                     /locus_tag="ACG8M1_000935"
     CDS             complement(22811..22954)
                     /locus_tag="ACG8M1_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFQ0421666.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23176..23655)
                     /locus_tag="ACG8M1_000936"
     CDS             complement(23176..23655)
                     /locus_tag="ACG8M1_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0421667.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23728..24012)
                     /locus_tag="ACG8M1_000937"
     CDS             complement(23728..24012)
                     /locus_tag="ACG8M1_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421668.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24090..24284)
                     /gene="ssrS"
                     /locus_tag="ACG8M1_000938"
     ncRNA           complement(24090..24284)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACG8M1_000938"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24356..25642)
                     /locus_tag="ACG8M1_000939"
     CDS             complement(24356..25642)
                     /locus_tag="ACG8M1_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFQ0421669.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25780..26451
                     /locus_tag="ACG8M1_000940"
     CDS             25780..26451
                     /locus_tag="ACG8M1_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFQ0421670.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26417..26905
                     /locus_tag="ACG8M1_000941"
     CDS             26417..26905
                     /locus_tag="ACG8M1_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFQ0421671.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26918..27865
                     /gene="prmA"
                     /locus_tag="ACG8M1_000942"
     CDS             26918..27865
                     /gene="prmA"
                     /locus_tag="ACG8M1_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFQ0421672.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27866..28630
                     /locus_tag="ACG8M1_000943"
     CDS             27866..28630
                     /locus_tag="ACG8M1_000943"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFQ0421673.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28863..31076
                     /locus_tag="ACG8M1_000944"
     CDS             28863..31076
                     /locus_tag="ACG8M1_000944"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFQ0421674.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31087..31533
                     /gene="dtd"
                     /locus_tag="ACG8M1_000945"
     CDS             31087..31533
                     /gene="dtd"
                     /locus_tag="ACG8M1_000945"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFQ0421675.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31704..32963
                     /locus_tag="ACG8M1_000946"
     CDS             31704..32963
                     /locus_tag="ACG8M1_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFQ0421676.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33052..33999)
                     /locus_tag="ACG8M1_000947"
     CDS             complement(33052..33999)
                     /locus_tag="ACG8M1_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0421677.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34393..35685
                     /gene="hisS"
                     /locus_tag="ACG8M1_000948"
     CDS             34393..35685
                     /gene="hisS"
                     /locus_tag="ACG8M1_000948"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFQ0421678.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35700..37469
                     /gene="aspS"
                     /locus_tag="ACG8M1_000949"
     CDS             35700..37469
                     /gene="aspS"
                     /locus_tag="ACG8M1_000949"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFQ0421679.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37578..38453
                     /locus_tag="ACG8M1_000950"
     CDS             37578..38453
                     /locus_tag="ACG8M1_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0421680.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38719..40602
                     /locus_tag="ACG8M1_000951"
     CDS             38719..40602
                     /locus_tag="ACG8M1_000951"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0421681.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40677..40961)
                     /locus_tag="ACG8M1_000952"
     CDS             complement(40677..40961)
                     /locus_tag="ACG8M1_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFQ0421682.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40951..41685)
                     /locus_tag="ACG8M1_000953"
     CDS             complement(40951..41685)
                     /locus_tag="ACG8M1_000953"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFQ0421683.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41814..42437
                     /locus_tag="ACG8M1_000954"
     CDS             41814..42437
                     /locus_tag="ACG8M1_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFQ0421684.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42629..43750
                     /locus_tag="ACG8M1_000955"
     CDS             42629..43750
                     /locus_tag="ACG8M1_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFQ0421685.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43757..46885
                     /locus_tag="ACG8M1_000956"
     CDS             43757..46885
                     /locus_tag="ACG8M1_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0421686.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLNLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46904..50098
                     /locus_tag="ACG8M1_000957"
     CDS             46904..50098
                     /locus_tag="ACG8M1_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFQ0421687.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFHQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50244..50951)
                     /locus_tag="ACG8M1_000958"
     CDS             complement(50244..50951)
                     /locus_tag="ACG8M1_000958"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0421688.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16795 a         8953 c        10641 g        14911 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc ttgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatctcaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggctt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg aaactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccctggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttat
    23041 tttacttgaa ctcattgact gttttccctt tattttaaac attataaaga ccgatgagtg
    23101 cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa aaaaacctgc cgatagttgg
    23161 caggtcgtct acgtgttaag ctttggtgtg gtctttagct ggcaattggt tttctaaatc
    23221 agttcggaca acaagcacat cgcaagctgc gtttctaata acatattcag aaacagaacc
    23281 aataaataaa cgttctacag cattcaatcc tgtggctcct aacataatca aatctacttg
    23341 attatcttct gggatttctc tggcaataat ttgttttggt gagccatatt ctacgacaga
    23401 ggttacatta ttcaagccag ctttcttcgc attgctttca taatctgcca atgtttgctt
    23461 tgccatttca gtagcttgtt ctgcaagcat tccatcaaag gatgaaacgg tttggaaaga
    23521 acgtgtgtca atgacatgtg ctaatagaag ttctccgtta tttcggatag ctacattgac
    23581 cgccttttta aaagctaatt cagcttcatc agaaccatct acggcaacca tgattttttt
    23641 gtattgttgt aacataagca ttcactcctc aagtcaatcg tattgtactc ttttattgta
    23701 gaacacttta gggaaaaaga gaattattta ctgctttggt tcagcaattt tttttgcaaa
    23761 tcggatactg aaggtggcag aaacaataat tacgatcagt aaaaagacca aggcaataaa
    23821 gcgttgattg aaaaaagctg ttaaaatacc cattacgcct aaaacagcat atgcagcacc
    23881 gtaaaattgt aggaatcctt gatttttatc atttttgttg atcaatacaa aaaagatatc
    23941 ctgtttatta aataaataat agctaacgaa taataatact aaagtggcga taatcattaa
    24001 aatcctaatc atgaacaaat cctccaaaat aagcaacaaa tagaaaaagc aatttgccaa
    24061 gagcaaattg ctttattctt taaaagatgg taatctccgt taatgccgtt gtttgtcctg
    24121 tagtattgat cccgcgaatt caagcaggtg ggtcccatgg tcgtagcttc gaactaccaa
    24181 atgataaggc atgttaccag cagtgacaca agacgggtcc caagatatca ataaaaatgt
    24241 tcggtcaaca cacaaagagg acaattcgaa catcacagat ttcccacctc tatagtagca
    24301 tatgaattta aaaagagcaa tgagagagct cgcagaaaca gaaccgtttt cttgtctagt
    24361 tttttggagg atgctttttc cactctttta tacggtaata ctgttgaccc agagcctgtt
    24421 catatttccc tgtatctttt ggctgataat actgagcatt cttcagttta tctggtaaat
    24481 attgctgatt gacccaagcc tgatcaaaat gatgaggata ctgataaccc acgccacggt
    24541 tgagtgattt cgcacctttg taatggctat ctctcaaatg atcaggaaca tctccagctt
    24601 tgccctctcg aatatcagca agtgctgcat ctaatgccat gtaggcagaa ttggattttg
    24661 gcgacaagca aagatcgacg acgacgtctg ctagtgggat acgtgcctca ggcaatccca
    24721 atttttcagc agctaataca gcgttcactg tacgagccgc agcagcagga ttacctaaac
    24781 ctatatcttc ataaccgata accatcagac gccggcaaat acttgccaga tcacctgcct
    24841 caactaaacg ggcgagataa tgaagtgcag catccacatc acttccacga atcgattttt
    24901 gaaaagccga aataacgtca taatgagcat ctccattttt gtcatgggta agagcttttc
    24961 tttggacaca ttcttcaatg atcgacagtg taagatgaat ccttccttct ttatctgaag
    25021 gagtcgatag tgtagccagt tccagcccat tcaatgcact ccgcaaatcg ccgttcgttg
    25081 cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat tgcttgttgt ccaaggccgc
    25141 gttctttatc ccttaaagca tgttcgactg ccaactggat gtcttgttct gttaatggtt
    25201 tgacttcaaa gatctgtgta cggctgcgga tcgctggatt gatggtaata taaggattct
    25261 cagtagtcgc tccgatcaag atgattcggc cactttctaa atgaggaagc agaaaatcct
    25321 gttttgtttt atctaatcgg tgtacttcat ccaataagag gatcactgta ccactcattt
    25381 ttgcttcttc cgctacaact tgtagatcct tttttgaatc tgtagcggcg tttagcatgc
    25441 gaaatgcata attagtagag ccggcgatcg cacttgcgat actcgttttt ccagtaccag
    25501 gaggtccata tagaatcatg gaagagagca tgcgagcatc gaccatgcgg cgtatgattt
    25561 ttccttcccc gactagatgc tgctgaccaa cgacttcatc gatcgttcga ggtctcatgc
    25621 gataagccaa tggctgttgc ataggatttt cctccttctt gtttttacgt cccttaatta
    25681 tatcatattt agcaagatgc ctagaaagaa cagccttctg ttgttttgtt ttcatagctt
    25741 atccaactaa tattgtgtat gataaagtag gtgagaaaaa tgacggataa acaaaagata
    25801 gatgaatttt tttggaataa aacgacgcca gaagtggcac gggatttatt ggggatgtat
    25861 ttggagcatg acacaccaga aggaagatta gctggatata ttgtagacgc ggaagcatac
    25921 ctaggtccag aagacgaggc cgcccatagc tatggtttaa gaagaacacc gcgtgtgcgg
    25981 gcaatgtatg aaaaaccagg tacgatctac ctttacacga tgcatactca tcggattttg
    26041 aacatcatta ctcagccaga agggattcct caaggagtaa tgatacgtgc aatcgaaccc
    26101 gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa aaactggtcc agatatcagc
    26161 aacggtccgg gaaaattagt ggaagcatta gcaattcctc aagaacttta tggtcagtct
    26221 atagcagata gttcgttacg cttagttttt gagaaaaaaa agacaccaaa aaagatcaat
    26281 gctttgccta gaatcggtat cccaaacaaa ggtgtatgga cagaaaagcc gttgcgtttt
    26341 gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa accaaatcga gaaagattgg
    26401 ggttggagga aagaaaatga aaaagaagga tctattaaca tatttagatg aaataattga
    26461 aaaacaagtg acagactatg atgtagcttt agattgggat acaaaaaatc atacgatcga
    26521 gatcgttgtt cgcttgtttg cagaaaataa agcacaattt gagattgatg atgcagaagg
    26581 gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc gtacttcttt ttaatcctca
    26641 gaaatctgtt tttgatgaac gcaattatct agcagtaatc ccttatgaag gaaaaaaagg
    26701 gttggcaaaa tcagtagctg attctttagt ggaatatcta aatgaagtat tagctcaagg
    26761 gcaaagcgat ttgcttgatt ttttggatga agacgatgac gaagctgtat tcgagcttca
    26821 ctgggataat caacaactag cagaattagt agaagtaaaa cagcaaaatg aagcagatac
    26881 ttatttaccg tacccaagtt attaaggagt gacagatatg aaatggaatg aagtaaaagt
    26941 agaaactgaa agtgaagcag tcgaagcagt tgctaatatt ttgatggagg caggggcgag
    27001 tggtgtcgcg attgaagatt ctttagatgt tgaacatttt cagtcggatc aatatggtga
    27061 gattttagat aaaaatgatt ttacatcgct gaaagaaggc gcactagtca tggcttattt
    27121 tccggaaacg actttcttac cggaaatctt gccttttatc aaagatcgta tcacacaatt
    27181 acctgagttt ggtctagcta ttggaaaaaa taaagtaaca gttagtgaag tagaggaaag
    27241 caactgggca acagcctgga agaaatacta tcatccggtg cgtattacgc gaatgctgac
    27301 ggttgcgcca agctgggaaa actaccagac agaagatcct ctagaaaaaa ttatcacact
    27361 agatcctggt atggcatttg gcacaggcac tcatcccacg acttccttga cattgacagc
    27421 actagaaaca gtcttgcgtg gtggtgaaac attgctagat gtgggaactg ggtcgggcgt
    27481 gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc tatgcctttg atttagacga
    27541 agtagccgtt cgttcggcga aagaaaatat ggatatgaat gaaatagcca aagatgtcca
    27601 tgtatcagct aacgatcttt tgacaggaat cgagattgaa agtgatgtaa tcgttgcgaa
    27661 cattttagca gatatcatct tattgatgat cccagatgct tggcgtttac tgaagcaaac
    27721 aggcacgctg atcgtttcag gaatcattga agagaagaag caaatggttc tggatgccat
    27781 gttagaacaa gggtttatcg tggatcaaat tttccagcaa aaagactggt atgcaattat
    27841 tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt ttaaaagaat catatgaatc
    27901 aaaagactat tttgttttag aaggggaaaa ctatcaccac attgtacggg ttatgaggat
    27961 ggaacccgag gatgaagttt ttttggcatt caatgatcaa atagccattg ttgcagaaat
    28021 cacggagatt actgaagagg ctgtttatct gaaagaaatt aaaaaagaag aaaatcaaaa
    28081 ggaactgcca agttcgatta ccatagcgag tggctatcct aaaggggaaa agctggattg
    28141 gatcgttcag aaatccactg aattaggagc gcaagctttt cttggtttcc cggcatcagc
    28201 ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga caacaacggc ttgaaaagat
    28261 tgctcaagag gcagcggaac aatcccatcg gcagatcgtg ccatcagtag agttattgga
    28321 aacgaaacaa gatttatttg agcggctaga tgattatgac gtggtcttgg ttgcttatga
    28381 ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa attcttagtg aaacaaaacc
    28441 agatagtcga atcttagctg tctttggacc agaaggtgga ttatcccgcg atgaagtcga
    28501 ttattttgta gaacacaaag ggatactttg tggattagga ccaagaatcc ttcgtacaga
    28561 aacagcacct ctttatttat taagtgctgc tagctatcaa tgggaattaa tgaatccttc
    28621 tttcagctaa cgttcttcat taataaaaga gtatcgacag aaagaattga aaaaatagtc
    28681 aacaatttgt ataatagaaa caattattta tacaatggat acgaaaaatc gtttgaaaaa
    28741 gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac tgcacggatt ttgggacaat
    28801 tatcaaacag atatttgtcc cgattcccgt tttaccgaaa aaagaaaggg ggatcgattc
    28861 ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat aaagctcgtt agtcaataca
    28921 tgggtcccga acatgtagca tttgttgaga aagcatgcga atacgcgact gctgcacatg
    28981 acggacagtt tagaaaatca ggcgaaccct acattattca tcctatccaa gtcgcaggta
    29041 tattagcaga tttaaaaatg gatccccata cagtggctac aggcttctta catgatgttg
    29101 ttgaagatac agaaatcact ttagaagatc tgagagaaga atttggcgat gacgttgcta
    29161 tgttagtgga cggcgtaacc aaattaggga aaataaaata taaatcccac gaagagcagc
    29221 tagcagaaaa ccaccgaaag atgctgctag caatggctca agatttacga gttatcatgg
    29281 tcaaattagc tgatagacta cataacatgc gtacgttgaa gcacctgcga gaagataagc
    29341 aaagaaggat cgctcaggaa actttagaaa tctatgcgcc tcttgcacat cgtctaggga
    29401 tcagccggat caaatgggaa ttagaagata cagcacttcg ttatctaaat ccaaaacagt
    29461 attaccgtat cgtccacttg atgcagacga agagagaaga acgtgaaaaa tacgtaagtg
    29521 gtactgttga agatattcga atagcgacag aagagctggg gatttttgca gaaatctatg
    29581 gacggccaaa acacatttat tcaatctatc gtaaaatgaa agatcagaaa aagcagttca
    29641 acgaaattta tgacttgcta gctattcgag tgatcgtaga ttcaatcaag gattgttatg
    29701 ctgtattagg agcaatccac acaaaatgga aaccaatgcc cggcagattt aaggattata
    29761 ttgccatgcc aaaagctaat atgtaccaat ctttgcatac taccgtgatc ggtccggcag
    29821 gaaatccggt agaaattcaa atccgaacac aggaaatgca tgaaatcgct gaattcgggg
    29881 ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa agtagaacca gatggtatga
    29941 cgaaacaatt aagctggttc catgagatac tcgaacttca agacgaaagc tatgatgctt
    30001 ctgaatttat ggaaggcgta aaaggagata tctttagtga taaagtctac gtcttcacac
    30061 caaaaggaga cgttactgag ttaccaaaag gatccggacc attggacttt gcatacagta
    30121 tccatacaga tatcggtaac aaaaccactg gtgcaaaagt aaatggcaaa atggtgcagc
    30181 ttgattacaa attgaaaaac ggagatatca ttgagatcat gacttctcca aattcatttg
    30241 gcccaagtcg cgactggttg aaattagttg ctactagcaa agcaagaaat aagatcaaac
    30301 gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa aggccacgaa tccgtggtca
    30361 aatgtattac agatctagga tttacgccta aagatatttt gacgaagaac aaactgcaag
    30421 aagcactcga tcgttttaat tatcaaacag aagatgatct ctatgcagct gtagggtatg
    30481 gagaagttag ccccttgacg atggccaatc gtctgactga aaaagaacgt aaagaacaaa
    30541 aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa tcagccgaaa aaagaacctg
    30601 acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca aggggtagaa aacttactaa
    30661 ttcgtatcag tcgctgctgt aatccgattc ctggtgatga tatcgttggt tatatcacta
    30721 aaggcagagg gatatccatt catcgtcgag attgtccgaa tgttcagcct gacaaaccaa
    30781 atgtagcaga acgtttgatt gaagtcgaat gggaagatac atcgaataca cgaaaagagt
    30841 atgatgcaga tttggaaatt tacggctata atcgttcagg cttattgaat gatgtacttc
    30901 aaacagtcaa tgcgctaacg aaaaatctca acagcgttga agcacggacg aataaagata
    30961 aaatggcgac gatccatttg acggttggta tccagaattt atcccaccta aagagtatcg
    31021 tggataaaat caaagcagta cctgatgtct acagtgtacg ccggacgaat ggataggagg
    31081 acagatatga gagcagttgt tcaacgggta agtaaagctg ctgtgtcagt cgatcagcaa
    31141 gaaattggaa aaattggcta cggcctactt gttttattag gcattcatga aaccgatacg
    31201 caaaaagatg tggactatct ggtaaaaaaa attgcacaaa tgcgtatttt tgaagatgaa
    31261 caaggaaaaa tgaatattag tgtagaagat gtgggaggac aaattttaag tatctctcaa
    31321 ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa gctttgtgga agccgcacga
    31381 ccagaaacag ctattccttt atacgaatca ttcaatgaag gaatcagaag tcgcggcatc
    31441 acagtcgcta ccggacaatt cggagcagat atgtcggttt ctctcgtcaa tgatggacct
    31501 gtaacgatca ttattgattc taaaaacaaa taaagtaatc tggttttcac tagtaaaaac
    31561 tatgaaacac gtcgcttaag ttagactgat aaactctaac ttaagtggct tttttgtctg
    31621 caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta agcttaaatt atacaagtta
    31681 ttttttatag gaggttgctg aagatgaaag aagtaccagt agtagatatc aaaatcacag
    31741 atttaaaaaa attgtatcaa aaaggataca acatgttgga ggagttacgc catgaagcgg
    31801 acgctcccgt cgtcaaagca aagattttca ataaagaagc tatcacgatc tacggatcat
    31861 cagcagcaaa agtattttat gatccaagga atttcaaacg aaaaggtgct atgccaaaat
    31921 tagtattgaa gacacttttt ggtcaaggtg gagtacagac tttggatgga gctgctcatc
    31981 accatcggaa aaatattttt atggatctaa tgacaccgga aagaatggaa gattatcatc
    32041 gtatcttaga taagaatctg acacaagcac ttgaagcaca gcatggtcaa tttgaactat
    32101 ttgatttaag taagatggtt ttctttacat ctatttgcga gtgggcaggt atcaatttat
    32161 cagcgatttc taaagatgag gtcgaaaaat tagcagaata tcaaatctct atgatcagcg
    32221 gaacgtttac ttctccgatt gatcacataa aaggtgtcga gaatcgcaaa aaatcagaaa
    32281 aatgggcgca aggcttgatt gaagaagctc gacaaaatcc tgtggctgga aaagaaaatg
    32341 tggcattata tgcttttgcc aatgccacag atttagatgg tcagctttta cctctggaag
    32401 tggcagctgt tgaattattg aacatcatcc gtccaacggt tgctctaact gtgtgggcgg
    32461 cattgatggg acatgcactt ttcagtagac cagatttgta tcagcaatta aaaaatgact
    32521 tttcgacgtt acaagatccg tttattcaag aaatgagacg ctattatcct ttcttcccaa
    32581 tgctacctgc gatttcgctg aaagaagtag aagtagatgg ttatcgtata ccagaaggca
    32641 gttgggttat tttagattta tatggaacag accatgatga acgaacagtt gaagcgccag
    32701 attcctttat gatcaaacgg tatgtaggga aagcaaaaga tatttcctat aaagaagaat
    32761 atgagatgat tgcacaaggc gggggaaatt ttcgacaaat gcatcgctgt gcaggagaat
    32821 ggatcactct tcatagtcta cgtgtgtttt ccgatcagct agtaaataag tttgagttct
    32881 ctgtacctga acaagattgg acgattccat tcaatcagtt tccgacttat ccgaatagcc
    32941 gagcgctact ttacaagaat tagattagca taaacttatc gaaaaaaagg aagatcaaac
    33001 agtgctgatc ttcctttttt catattacta taaattgata aggtcaattg atcaaaatcc
    33061 acgaaatgct tcatcaatgg tttgataatc ttcattggat aaatgcaaat ctaaagcttg
    33121 gacattgtca gatacttgct ctggacgctt agctccaggt ataactacag acactcgtgg
    33181 attcttcatg taccaagcta aaacaagttg cgcaggagtg gcttggtatc ttttagcaat
    33241 ggggcgaagt acatcgacag cggttaaaat ttctctgaaa cgttctcctt ggaaatctgg
    33301 atttcttttt cgaggatctc cttcaccaaa ttgtttttcc tcaccaagtt catattttcc
    33361 tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa ctgattttgt ttttttcaag
    33421 ataagggaat aattcttttt cagcctgccg atggatcaaa ctgtatttat cttctactac
    33481 atcgacatat ccatctgcat tcgcttcttt caattgttct aacgtgaagt ttgacacacc
    33541 gactgctcgg atttttcctg cttcttttaa ttcgtgcaat gtagcaactg attcattttt
    33601 tggtgtgctt tcatccggaa agtggatata aaaaatgtcg atgtaatcag tttgcagacg
    33661 ttttagtgca tcttccaccg attgtttgag aaactcagga gaattatcaa atgttcgccc
    33721 tttatttggt acatgagcag cttttgtagc gatgacgaca cgtgagcgat catattcttt
    33781 ttccttcagt acctcgccaa tcagttcttc ggaacggccg tttccgtaag cataagcggt
    33841 atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact acttgttttc ctgtctcatc
    33901 ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt gctcctaatc caagctgttc
    33961 tgcgtagact tgtgaatgtc cgattcttat ttctgccata gctgattcct cctttttgtc
    34021 tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt tttgtgaggg gaaatagtca
    34081 gatatctctt gactttgaga ctggttttta gtaggttata agtaatatcg aatgtcaatg
    34141 aaagagcgag taagtttttg aaactttaca agagaggatc atcgaggctg aaaatgatct
    34201 aaagtttcat tagcctaaag acactctgga gatggacgag tgaaaagccg tcccgcgtac
    34261 gagcgttatt cgtaagagga aagagaaatc tttcaaaatt aggtggtacc gtgtatgaat
    34321 ttcattcacc cttgttcatg atgaacaagg gtgatttttt tatttacata gctaagaaag
    34381 ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa atgatatttt gccaggcgaa
    34441 tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat tattcagaga ttatcagtat
    34501 aatgaaatgc gtacaccgat ttttgaacac tatgaagtga tatcccgaag tgtaggggat
    34561 acaacggata tcgtttcaaa agagatgtat gatttttatg acaaagggga acgccatgtg
    34621 acgcttcgac cagaaggtac agcaccaatc gttcgttctt ttgttgagca taaattgttc
    34681 ggcccagagt atgcgaaacc gttcaaaact ttttatatgg gaccaatgtt tcgctacgaa
    34741 cgccctcaaa aaggacggtt acgtcaattc catcaaatcg gagtagaagc atttggatca
    34801 gaaaaccctg caactgatgt ggagagcatg gtgatggcac ttgatttctt caaacagttg
    34861 gggatcacgc aaatccggct agtcatcaat tcattaggtg ataaagaaac gcgtcaagcc
    34921 tatcgtcaag cattgatcga ctatctttta ccttttgaat cagagctgag tgaagactct
    34981 aaacgccgcc ttcatgaaaa tccattacgc gtattggaca gtaaagacaa acgagatcaa
    35041 aaatttgtgg cagaagctcc atctatctta gattatctaa gcgagcctgc tcaaaaacat
    35101 tttgataccg ttgtttccat gctggatgca ttggctgttc cttatgaaat cgacagtaat
    35161 atggttcgcg gactagatta ttacacacat acgatttttg aaatcatgag tgacgcacca
    35221 aaaatggggg cacaagcaac gatttgcgca ggcggacgtt atgacaatct agtggaagaa
    35281 ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg gtatcgagcg attactcttg
    35341 actatggagg cagaggaagt agttatccct gcatttaatg agttggatgc ttacgtggtc
    35401 gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg tccaagcgat tcgaaacttt
    35461 ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa aagcgcaatt taagacagca
    35521 gataaagcga atgccaaatt agtattggtg atcggtgaag atgagcttgc tagtcaaacg
    35581 attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt ttccattaga agagatatat
    35641 gaacattttg atgaagtcta tgatgaaatg actttattcg agtaggagga aaaaaataaa
    35701 tggcacaaag aacgatctat tgcggattag tttccgaaca acaattagaa caaacagtta
    35761 cattaaaagg atgggtacaa aaaagacgag accttggggg agtaatcttt atcgacctac
    35821 gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga aatcaacaaa gaagcatggg
    35881 aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt gactggggaa gttagaagac
    35941 gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga attcgaagtg attgcaagtg
    36001 aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca aattgaagat gatcaagcaa
    36061 tcagtgacga aatacgtttg aaatatcgtt atttggatct gcgtcgtcca aaaatgacta
    36121 aaaacatcaa attaagaaat gcgacaacaa aagcgattcg tcattattta gatgataatg
    36181 actttctcga tatcgaaaca ccttacctag ggaaatctac accagaaggc gcaagagact
    36241 acctagttcc ttcacgtgtc catgctggac atttctatgc gttgccgcaa tctcctcaat
    36301 tgtttaaaca attgctgatg aatgctggat tcgaccgtta ttatcaaatc gttcgttgtt
    36361 tccgcgatga agatttacgt ggagaccgtc agcctgaatt tacgcaagta gatattgaaa
    36421 caacgttctt aacagcagaa gaaatccaaa cttacacaga gggattgatt gcgaaggtaa
    36481 tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc tcgtatgacc tatgatgaag
    36541 caatggctcg ctacggcagc gacaaaccgg atacacgttt tgatatggaa ttgatcgatc
    36601 taagcgatac agtcaaagaa gtagaattca aagtcttcca aatggctctt gaaaacggcg
    36661 gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg ctactcacga aaagacatgg
    36721 atcagttagg tcaatatgta ggacaattcg gagctaaggg gcttgcatgg ctgaaagtag
    36781 aagaagacgg attgaaaggt ccaattgcta aattcatggg agaagcaaca gaagcaatca
    36841 ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt tggcgcagat aaaagtgaaa
    36901 tcgtcgctgc tgcattaggt gctatccgga cacgtttagg aaaagaatta ggactaattg
    36961 atgaatcgaa attcaatttc ttatgggtaa ctgattggcc acaatttgaa ttttcagaag
    37021 aagaaggtcg atatgtctct gctcaccatc cattcacgat gccaaaagaa gaagatatcc
    37081 cgttattggc tgaagaccct gcaaaagtct atgcagaagc ttatgatatc gtcttgaacg
    37141 gttatgaatt aggcggaggt tctatccgta ttcatactcg tgagcttcaa gaaaaagtac
    37201 tagaaactct aggctttaca aaagaacaaa tggaagaaca atttggtttc ttgttaacag
    37261 ctttagatta cggattccct ccacatggcg gtattgcatt aggattggac cgttttgcaa
    37321 tgttattagc cggagaagat aatattcgtg aagtcattgc ctttcctaaa aacggaaaag
    37381 cagcagatgt gatgagtgat gcaccaagta tggtttcgcc tttacaattg ttcgaattga
    37441 atattgatgt aacgaatata gaagaatagc cgataaaaag gtaaaaagga tttgtcgaat
    37501 acgcttcttt tgacaacctt gatttaattg aaaaacactt tataatgaag ccataacata
    37561 taaagcgggg cttttccatg aaaaaaacat tcgaaaattg ggcttatcat gattacacga
    37621 ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc agtcgcattg aatttctttt
    37681 atcagccagg acatatttat tcaagtggta ttactggtct agctcagatt ttgacgactt
    37741 tgtcaaaatc actgatagga ttcgaagtac cggtatcaac aactttgtat ttactgaata
    37801 tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa gtttacaatt ttcactttta
    37861 tcacagtcac tttgacctcc ctttgtatcc atattttacc ggaaacagtc ctatctaccg
    37921 atccaatcat ctgtgcgttg tttggggggg ctgtgatggg actaggtatt gggctagcgt
    37981 tgagaaacgg cctatcatcg ggcggtctag atatcgtgag tatcacgatt cgtaaaaaaa
    38041 caggaaagtc gattggttct atttcgatct acttcaatgc attgatcgtt tttgttgccg
    38101 gaattctatt tggctggcaa tatatgtttt acagtacgtt gtctattttc gtcagtggaa
    38161 aagtaactga tgtcgtttat actaaacaaa agaagatgca ggtaatgatc gtaacgaaac
    38221 atccagaaaa agtagtaaat gaaatccaaa actgtatgcg tagagggatc acgatcatca
    38281 atgaagcaga aggtgcttat aagcatgata agcagacagt attgatgacg atcgttacac
    38341 gatacgaact gcctctactt agagaagcaa tgaaagcttc tgatccacaa gcttttgtaa
    38401 gtattgcaga aaacgtccag atacttggtc gtttctatga ggatggcatt tagatcgagt
    38461 ttgacaaaaa ttcatgaaat actgctgtag acagacgttc gtttgtctgc agtttttttc
    38521 taccatagta gaatcagcaa agaaaaactg cttttttatt tgaaattttc ttaaagttga
    38581 aaaaaagcat gtttattttt ttaaatttat gggatgatag aaaaaaatag tagagaaagg
    38641 acacgattct acttgctatt ttcacttaat acccgtatat tacgaatgaa aaaagtttat
    38701 gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa aaaacagccg ctacatcact
    38761 gggtttgatg ggctccgttc attagctgtg gtgggtgtta tcttctatca ccttctgcca
    38821 actagtatga aaggcggcta tttgggcgtt ccgatttttt tcgtcgtatc tggttatttg
    38881 atcacggatc tgctgcggca ggaatgggaa caaaatggaa aaatcaatat ttggcaattt
    38941 tatgtcagaa gaatgaagag actctatccg gcacttgttt ttatgcttgt gacagcttcg
    39001 gcttatatca ctttgtttca gcgagggctg ttaaacaatc ttcgaggagt tgtggtcagc
    39061 agcttactgt atgtcaacaa ctggtggcaa atcaataacg gtttatctta tttcgatcga
    39121 tttgctaatg agtcaccgtt tacgcatatc tggtctttag cagtagaagg tcaaaactat
    39181 ttggtttggc cgatcttgtt tgtattgttg atggtatttg ttcgtaaaag aaaatggatc
    39241 ttttatactg tgttaggtac atccttcctc tccgccatct tgatgatgat cttgtataca
    39301 ccaggaggcg atccaacccg tgtttattac ggtaccgaca ctcgtctgtt ttctatatgg
    39361 ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt taaagaaaaa catcccgaaa
    39421 caagcgaaaa atattctgaa tatcgctgga ggaatctcgc ttttggcact gattctttgc
    39481 ttcttctttt tagatgatca ttacaatttc atctattacg gaggaatgct cctagtgagt
    39541 ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg gagcaagttt gaatcgatgg
    39601 ctgacaaatc cagtatttac ttggattggc aaacgaagct atggcattta tctgtatcag
    39661 tttccagtta tgatttttta tgaagcaaag gtgactgata ttgccgatca tgttttgttg
    39721 catactttag tggaaatcac attgattcta atcatcagtg aactttctta tcgatatgtg
    39781 gagcgtccgc tagcacgttt tgattatggt cgtacattcc aagtgatgaa aggatggttc
    39841 agcaaaccga tcatcagtaa gagcaaacca tgggttgttc caggcacatt acttgtagca
    39901 attgcactcg ttggtttcgt tacggcaccg aaaaacgctg taacagccga tcaaaaacaa
    39961 ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag aaaccagaaa caattcagaa
    40021 aacaccacta gttcggttga ccaagcgatc cttgataagt acgagttgtc caaggcacaa
    40081 gggaataagg cacaaaaatt agaactaacg gcatttggtg attcagttat gttggatgct
    40141 gcaacggatc tacaagaact ttatccaaaa gtagtggtag atggagatgt cggacgacaa
    40201 ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac aagatttgtt gaaagacact
    40261 gttctgattg gactaggaac gaatggctca ttctcggaag ctcagtttga tagtgtgatg
    40321 gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc gagtaccgac gaagcgctgg
    40381 caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa aatacgacaa tatgacgctg
    40441 attgattggt acagctacag taatgaccat agtgactggt tttatgatga tcaagtccat
    40501 ccaaatcctg aagggatgac acattacatt cacttagtca gcgaagcctt gctaggagga
    40561 agttcaagta cgaacagcag tgagacaaac gtgacagaat gatagctaca aaaaacttca
    40621 ggcaaaaaca tttgtttttg cctgaagttt ttttatattt accgtgtttt taacattcat
    40681 atagattcag gaagcaaaac ggttgagtgt gtctgtaaat aacgttcttt ttgttttcgg
    40741 gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc ttcttgaaga aaatacttct
    40801 gcatggatca tcttaacagg tcttcttttt tgaagacgag tatatttagc accagtacca
    40861 ttgttatgtt cctctaatcg tctagaaaga tcggttgtat atccaccata aaatgtctga
    40921 tctttacaga ataatacgta aaaataatgt tcatttgcca tagagcatct cacgaatctc
    40981 tgcagtgtat tctccatcca tattgtaagt gatcaatggt ggagcgactt tgaatccgtc
    41041 taatttgcct tctttgattc cttcaactaa caaaatattt gcctcttttc caggttttgg
    41101 gtaaacaaat tggatccttt taggtgcaat tcgatagtct tccatgacct gaatgatttc
    41161 taagaaccga tcaggacgat ggaccatagt aaagcgtcca tttgttttta gtagcttact
    41221 tgaaatatcg atcacttctt ctaacgtcgt atgaatctca tgacgggcga ttgccaggtg
    41281 tttattaggg ttcgttttat ttgttggcag ccctttgaaa taaggtggat tacagacgac
    41341 taagtcacaa gaattatgtc gaacgacaga taagctgtct ttcagatcga tggtgtggac
    41401 agtcatttgt tcatttaaat ggttaagcgc gatactacgt cttgccatgt ctgctagacg
    41461 aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt ttacttaaaa aaagtccaac
    41521 tgcgccattt cctgcacaaa ggtcaacaat cttccctttt ttaggtacac gggaaaagtg
    41581 agcaagcagc acagcatcta aagaaaaaga aaacactttg gaactttgga taatcttgat
    41641 atcttctgcg tataattggt cgattcgttc gtcttcgtga agcatggatt ccctccaaaa
    41701 tgaaaaaaat agtcgtctgt attatactat ttttattaaa aagaaccaag gtggcttgtc
    41761 aaacctctat tttttatgca tactatgacc ataagaaggg aaaggaagag actatgtttt
    41821 atcgatttat gcgcggggta gttcgagtac tattagcctt agttaatgga aatgcccgct
    41881 atgagaataa agaagtttta ccgcaagatg agaattacat actagttgct ccccatcgta
    41941 cttggtggga cccattatat ctggcggtag ctgcagcacc caaggaattc agctttatgg
    42001 caaaagaaga actgttcaaa aatccagttc tgcgatttat attaactcga tccaatgctt
    42061 ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa aacacctgta aagattttga
    42121 aatcgacaaa tttgagtttg atcatgtttc ccagtgggac aagacatgct acagaactta
    42181 aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa aatcgtgcca gctgtatatc
    42241 aaggtccgtt gacacttggg gatctgttca agcgtcagag agtgacagtg cgtttcggcg
    42301 aaccaatcga cttatcagat atcaagaaaa cggataaaga aggtatggcg gagatcgaac
    42361 gacgaacaca agcagctttt gacaaattgg acaaagaagt gaaccctgat ttcaaatatg
    42421 aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg gtcttttgaa tctactgtcc
    42481 tgttcagttc agactttttc aatgaaaacg agggagagac gtcaagtctg ccctcttttt
    42541 gcgttccaat atgtaaaata gaagacaggt gtcatgtaat ggatcaaagt gttataataa
    42601 ttagaaggac attttttgag gtgattgaat gcgtttttta catacagccg attggcatat
    42661 cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag cgtcatgtac tatcttctat
    42721 actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg attgccggag acttatatga
    42781 taggagtgtc ccagctgttg atgccgtaga attatacaat gaattgatgg tcgattggaa
    42841 tttaaaggaa aagatcccga tttttgctat atcaggaaat cacgatagca gtacgagact
    42901 ttcagcgggt acgccatggt tcagttattc gaactatttt ttgcgaacac agctagcaga
    42961 agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc tttcttcctt actttgaacc
    43021 aattgcagcg agattatatt ttgaagatga caatatccga acgatcaagc aagcggtagc
    43081 caaggtgata gataaaatgc aggagctatt tgattcagaa aaaaaacaag tattgattag
    43141 ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa acgaaaatcg aagtaggcgg
    43201 gttggattcg atccctggtg aactacttac accgtttgat tatgtagcac taggacattt
    43261 gcataatcaa gctgctttga gacaggataa tgctcgctat agcggttccc cattgaaatt
    43321 ctctttatct gagatcaacc aaaaaaaagg cgtatggatc gttgacctga caacaggcct
    43381 ggagttgaat tttagggaga tcgaacccct gcatgatatt gaagaaataa cagcgagttt
    43441 caaagaattg ctggatcctg ccttttatca gtccgtcaat cgggagaatt acatctatat
    43501 ctatctcact gatagaacga tcatcccgaa tatgatgaac cagcttcggc aaatatatcc
    43561 tcgtattttg gggattgaac gggcaaacgg tcgagcagaa caaacaaagc gcaaacgaaa
    43621 agtactagaa atgaaagatc ctcaaaaatt agcagaagca ttttttagtg aaatgacgga
    43681 agagcagcta actgcaaacc aagaaaaatg gctcggagaa acgttgcaag aaatcatgga
    43741 aatggaatga tcaagaatga aaccgaaaaa attacaactt aaaaattttg gtccttttat
    43801 caatgagacc gtagattttt cacgtttgac agaagcaccg ctttttttga tcagcgggaa
    43861 gacaggagct ggcaaaacga cgatttttga tgggatcacc ttcgcacttt ttggtgaaac
    43921 ttccggaaga cttcgctctg gaaaagagat gcgttctttg tttgctacac cagacgaaga
    43981 aacaagcgtg actttttctt ttgaacatca gcagatgagc tatgaaatcg aacgaaaacc
    44041 agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa aaacaggcag ccaaagtaac
    44101 gttgaccatt tttgatggga aaggaaaaga aataaaacaa atcacaaaac gtacagaagc
    44161 agatcagttg atcagagaac tgatgaatct cgatgcgaaa cagttttctc aaatcgtttt
    44221 actaccccaa ggagaattcc gtaatttttt ggtttcatca agcagtgata aagagactgt
    44281 tttacgtcat ttattcggta ctcaattttt ccaacagttc aatgagcgat taaaagaaaa
    44341 agcaaaacaa cagcaacaaa aattggatca tttagagcaa gagctgcatc ttctgcaaaa
    44401 aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg tttgaagccg ttttagccca
    44461 atggacaaac catcaggcaa tactcgaaaa acaaatcacg gaagaaaaag aagctctaac
    44521 ggaacttcag gaaaaacaaa agcaactaga aaattcctac tatcgttttg aaagcttgaa
    44581 aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa aaggaattag ctgctcaaaa
    44641 agacgaaata gaggaaaaga aacgatggat tgggtattat gaatttacgc aacgattagt
    44701 cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa atagaactgt cacaaaaaag
    44761 tagtgagcaa acaaagaaac tagcgatgac tacgcagaat tatgaagagt ggcaaaaaaa
    44821 tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa gctgctcaaa aactgcaaaa
    44881 caaacagatg atggtgccaa ttgtcgaatc cttacgtagt aaaaaacaag acgcagaaca
    44941 attaacaatt tcattggata aagaagaatt gaatgccgag aagctgtatc aaaatctcgc
    45001 tatctatcag gaaagaactc gaattcttca agaaaattta ctggatcagg aaaaactgca
    45061 agaagatcgt cttgcttttg gacagttaaa atatctagat gaaaagcagc aagaaataga
    45121 aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata agagaagaac tcaaaaaagc
    45181 aactgaagaa ataacaaaaa atagtcagct attgaaagaa cagacagaac aagcagaaca
    45241 gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt cagctttttt tgcgtccagg
    45301 ggagccatgt cttgtttgtg gatcaacgga acaccccata caacaattaa aacacgaaca
    45361 gccaaataag gaagatatct taaaagtaga acaacaactg gcagaagctg agtctgctgt
    45421 agaaagaact cagcaaatca ttgccaaaag tgaagcacat gaaaataatc ttcaacaaca
    45481 attatcagat ttagaacaaa aaatcatggc aacgaatata caattggctg aacaagaaga
    45541 acacttgcaa caggctttga aaaaggcatt tcctgagata acagaacaaa aaacaaaaac
    45601 aactcttgta gtaatcgaac aatctttaga tagacgaaaa agcaagatgg ccaatgcaag
    45661 aatagagctg gaagaaataa gacaacaagc agaaaagctc gaacaacaat tagctgtcta
    45721 caaacagcag cagacagaaa aaaataatca gctccagcaa ctgcaaggag aaatcaaaag
    45781 tttagaacaa caattgcaag atacggatag taactgttta gaagaggaga tacgacgact
    45841 tgaaaaacag ttagaagaag actcgaatca actagctgtt gagcagaaag caggagtgca
    45901 attgttgcaa gatcttcata cgcttcggac acagcttaat cttcaacatg aacaaataga
    45961 aaaaatagat gaaaaaatag aaaaggaaca agaaagaata gctaaaaagt tagaaagcca
    46021 gtcgtatttt tcaacaattg aagaaatctg tgcatttgca caacagcaag cacaatataa
    46081 agaaaaccaa cgtacagtta cttcttatca tgaagagcaa ttagtgacag ctgaccggct
    46141 gcgtcaatta gaaaatatcc agctaactga gacattccca gatacagaag agatcagcca
    46201 acagttagaa gaaataagac gtatgatcga aataaagcaa gaaaagatat acggtttaca
    46261 agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt ctttcgattt atcacacaag
    46321 ccagacgaaa ttagatgagc ttacgcaatt acagcagctt tcgcaaacat tcaacggaga
    46381 aaatcctaag aagactagtt tggaacggta tgtgcttcag gtttatcttc aagaagtgtt
    46441 acaagtagca aatgatcatc tccaacgttt aacgaaaaat cgttatcaat ttgagctagc
    46501 ggataccatt ggcagttatc gagggaaaac cggattagaa atcaatatct atgatgatca
    46561 ggcaggtatg tctcgaagtg cgcataccct gtctggcggt gagagtttta ttgcagcact
    46621 ttctttagca ttagctcttg ccgatgtgat ccagacacaa gctggtggtg tagcaatcga
    46681 tgcattgttt attgatgaag gatttgggtc attagatgaa gaagctttgg aaatggcaat
    46741 ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc ggcatcatta gtcatgtaag
    46801 agaattgaaa gaacgagtat tacaacaaat aagaattgat acagaaggta gcggacaaag
    46861 caaaatacgc tatcaacttg gataaaaagg gagattggta actatgaaat ggagtattcc
    46921 agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa ggccgagtgt tatcggttgt
    46981 ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg ggcagtgaat tgtatatggt
    47041 tgatttggat ggtacagcaa aagagataga ttactgccaa tgtccctatt gggaggaaca
    47101 taaatattgt aagcatacag ttgctgtgga actttattta cggtcgaaaa atctatctcg
    47161 tatcatgaaa aaagaccagc caatgctaga accggtaaaa gcaacaagtg agggagaaat
    47221 cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat cctcaagcgg tgcaaccttt
    47281 gattattgaa taccaagtag aaacgattga gactaatcag tatcacccag agctttctat
    47341 tttggcactt tacttgcgta tcggttcatt ggcatcaccg aaaaaaacat atatcgtaaa
    47401 aaacatctat gattttttac aagcttacac agaaaaagaa acttacactg ttaataaaca
    47461 gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa gatcaaaaaa tactcacgca
    47521 tcttgcagga agtgctcaga cgcatcaatt attaggtacg aacggcttac aagtcaaagg
    47581 aaaactagat aaaagatatc tgcttctccc agtagaacaa gcccgcttcc tgttagagca
    47641 gatgaatcag actacacgtt tgcatctgca gataaatgaa caaaacgatc aaggaataca
    47701 attttccgat caaaacaaac ctttatcatt caaagtggaa aaatttggag aagattattt
    47761 gctgcaagca ttgaatgatt ttgatttttt ctttatgcat tatcagtggg gagttatcca
    47821 agggacattt tattctctga cgaaatatca acaaacggtt tatcaaactt ggaaacaatt
    47881 gattcgccga ttggagaaac cagaagtagt gttcaagaaa aaagaattac cgtctttgtt
    47941 taaagagatt atccctctgc tgtcagagat cggcgacgta gctattgccc ctgcagtaga
    48001 agaggaagta gcagatatcc ccgtcgaatt tattttcttt ttccgaaaag caaaaggaaa
    48061 aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc tattcgactg acccgaagca
    48121 tgaggtctcg acagaacagg cttttcaggt gttacgtgac acagtagaag agaaacgagt
    48181 acttgatcta ttcagaatgt atcgctacca gaaaaatgaa actggttatg aacgtccatt
    48241 gccaagcggg gaagaactat atgccttttt ccgcacagaa ctatctgtct tccatcagtt
    48301 tggtgaagtc agacttggaa gaaaattgcg agagttgtat ttagatgcgc ataaacatca
    48361 accgaaaatc gaagtaaccg agaccggttc atggctcgat attcgattcg atgtgacagg
    48421 gatagaggag caagaaatcg atcatgtcct gcaaagcttg ctgagaaatg atgcttttta
    48481 tacattagaa aatggtcagg ttctttcttt tgattcagaa gaatttcaac aaacaagcca
    48541 agtgttgcaa caattacggg aatcgatacg tacagaagaa ggaacgatcc atgtacctaa
    48601 aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc aatgctactt ttagtgaatc
    48661 gttccaaacg atggtacaag atctcattca tccagaaaga taccaggcac agcttcccaa
    48721 aggattgaat gcaacgatga gagattatca aaagcaaggt tttcgatggt tgaagatgtt
    48781 aggtcattat cagtttggcg gtattttagc cgatgaaatg ggacttggga aaacactaca
    48841 gacaattgcc tttttacttt cggaaaaaga agaacggaaa agcttctctg ctttgatcgt
    48901 agcgcctgcg agcttaattt acaactggca ggcagaggtg agaaaattcg ccccttcttt
    48961 aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa gaattactgg ctaaagacac
    49021 agatatccga gtgacttctt atgccagctt aagacaggat ctagctaatt atcagtcgca
    49081 aaaaattgat tatttgattc ttgatgaggc acaaatggtc aaaaatagca gtacgaaaac
    49141 tgcacaagca ttgagagaat tagctgtacc tcagcggttt gcactgagtg ggacaccaat
    49201 cgagaataat ttagaagaat tgtggtcatt gtttgcaacg attatgccag gatttttccc
    49261 gactaaaaca aaattcaggg aacttgccgc agaagaaatt gcgcaaatga ttcgaccgtt
    49321 tattttacgg cgagataaac aaactgtgtt gaaagacttg ccggaaaaaa cagagatgaa
    49381 tctatattct gcacttacag aagaacaaaa aactgtttat ttagcttact tgcgtcaaat
    49441 gcgtgaagaa atcacatcaa tggattctga agcattcaag aaaaaccgga tcgggatact
    49501 tgctggtctg acaagactgc gacaaatttg ctgcgatcct cgtctgttta ttgaagatta
    49561 ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta ctggtagctg ccaaagagaa
    49621 caaacgaaga gttttgctgt tttctcaatt tacagggatg ctgactatct tgcaagaaga
    49681 gttagccgag ctagggatct cgacatttta tttaagaggc agtacgaaac cacaagatcg
    49741 gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat gtttttctga tttccttaaa
    49801 ggctggggga actggattga atctcacggg agcagatacg gtcatcttgt atgacctttg
    49861 gtggaatcct gccattgaag aacaagctgc tggacgtgca catcggatcg gacaaaaaaa
    49921 tgtggtagaa gtgtggcgta tgatctctga aggaacgatt gaggaacgca tggattcact
    49981 ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa ggtaatgaag aacagttgac
    50041 gaaactgact gaagaagaca tccgcatgat tttaagtgta ggagaaatcg aggagtaaga
    50101 gactcgaaaa agcgttcagt aatgggtaag aaagcctttc taaagaagcg attgtttatt
    50161 tgatttaaaa aatagcaagg aggctgggat tccattttat cccagcttcc ttgctatcat
    50221 ttttttattt ctatttttaa aggttataca aagattgtct tcattgtctc taacagctga
    50281 tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt caattttgcg ttctcgatgg
    50341 ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta gaacatcatt gtcgtaatta
    50401 tcgccaacgt ataaggtctc ttctggaagc atatgaaatt ctttctcagc cagctgaaaa
    50461 atctcttttt ctggtttttg gaaacctgtt gcttgagaaa tgagcatatt gcgggaagga
    50521 atccaattgt tcaattgaag ttgcttcagt ttttttgtct gatggtcagt cggcccattt
    50581 gtgataattc ctaatgggac attcttttcc ttcaagaaat cgagggtttt tttgacctcc
    50641 tcatgcaagc agatattatc aagttcttcc tcgtaaattt tttgaaataa gaggccatct
    50701 tcttccgtaa tatgagggta gtctaaatct tttagtgatt ggctgatccg atgtgctcgc
    50761 atatattcta gtgtccaatc tcctgccatt acttttggga agttttcatc actatgatgg
    50821 cggaaccgga tatatagtgg atgcatatct gcatctgaaa caagcggaac gactcttttg
    50881 accgcgtttc gaaatggctg ctgctgatca tacatcgtat catcaacatc aaacacaact
    50941 gatttaatca aaattttaca cgcctttcgg ttttcattga ttttttcaca aatccttgac
    51001 tattgtaaca gaaaaaattg tctaaaaaag ctgataaata aaggtttttc ttactatatt
    51061 tctatttcct tgacagaata aggtttttat atttcagttt ttttcactaa aaatcgtgaa
    51121 acacgtcaat aagtttgatg aacaaattaa tcattatggt agaagtcgat tgatttattt
    51181 taatgcaatc tctgtggaat tttcgaaaga tttatttttt taatacagtc tcaatataac
    51241 tattcaaaca taaaataacg ttatttgatt tatttgttta tagtaaattt tatttagtaa
//
LOCUS       DAZKNV010000015        49832 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000015 DAZKNV010000000
VERSION     DAZKNV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.015"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(25..222)
                     /locus_tag="ACG8M1_000959"
     CDS             complement(25..222)
                     /locus_tag="ACG8M1_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFQ0421689.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(616..2343)
                     /locus_tag="ACG8M1_000960"
     CDS             complement(616..2343)
                     /locus_tag="ACG8M1_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFQ0421690.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2336..3529)
                     /locus_tag="ACG8M1_000961"
     CDS             complement(2336..3529)
                     /locus_tag="ACG8M1_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0421691.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3716..4360)
                     /locus_tag="ACG8M1_000962"
     CDS             complement(3716..4360)
                     /locus_tag="ACG8M1_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0421692.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQAKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4454..4588)
                     /locus_tag="ACG8M1_000963"
     CDS             complement(4454..4588)
                     /locus_tag="ACG8M1_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFQ0421693.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4590..6722)
                     /gene="feoB"
                     /locus_tag="ACG8M1_000964"
     CDS             complement(4590..6722)
                     /gene="feoB"
                     /locus_tag="ACG8M1_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFQ0421694.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6719..7192)
                     /locus_tag="ACG8M1_000965"
     CDS             complement(6719..7192)
                     /locus_tag="ACG8M1_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFQ0421695.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7593..7817
                     /gene="nrdH"
                     /locus_tag="ACG8M1_000966"
     CDS             7593..7817
                     /gene="nrdH"
                     /locus_tag="ACG8M1_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFQ0421696.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7976..10135
                     /gene="nrdE"
                     /locus_tag="ACG8M1_000967"
     CDS             7976..10135
                     /gene="nrdE"
                     /locus_tag="ACG8M1_000967"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFQ0421697.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10185..11150
                     /gene="nrdF"
                     /locus_tag="ACG8M1_000968"
     CDS             10185..11150
                     /gene="nrdF"
                     /locus_tag="ACG8M1_000968"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFQ0421698.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11239..12378)
                     /locus_tag="ACG8M1_000969"
     CDS             complement(11239..12378)
                     /locus_tag="ACG8M1_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0421699.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12687..13400)
                     /locus_tag="ACG8M1_000970"
     CDS             complement(12687..13400)
                     /locus_tag="ACG8M1_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFQ0421700.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13654..14355)
                     /gene="nagB"
                     /locus_tag="ACG8M1_000971"
     CDS             complement(13654..14355)
                     /gene="nagB"
                     /locus_tag="ACG8M1_000971"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFQ0421701.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14589..16121
                     /locus_tag="ACG8M1_000972"
     CDS             14589..16121
                     /locus_tag="ACG8M1_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0421702.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16312..17514)
                     /locus_tag="ACG8M1_000973"
     CDS             complement(16312..17514)
                     /locus_tag="ACG8M1_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0421703.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17596..18285)
                     /locus_tag="ACG8M1_000974"
     CDS             complement(17596..18285)
                     /locus_tag="ACG8M1_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0421704.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18391..18759)
                     /gene="rplL"
                     /locus_tag="ACG8M1_000975"
     CDS             complement(18391..18759)
                     /gene="rplL"
                     /locus_tag="ACG8M1_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFQ0421705.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18812..19315)
                     /gene="rplJ"
                     /locus_tag="ACG8M1_000976"
     CDS             complement(18812..19315)
                     /gene="rplJ"
                     /locus_tag="ACG8M1_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFQ0421706.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19519..19646)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(19725..20414)
                     /gene="rplA"
                     /locus_tag="ACG8M1_000977"
     CDS             complement(19725..20414)
                     /gene="rplA"
                     /locus_tag="ACG8M1_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFQ0421707.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20518..20940)
                     /gene="rplK"
                     /locus_tag="ACG8M1_000978"
     CDS             complement(20518..20940)
                     /gene="rplK"
                     /locus_tag="ACG8M1_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFQ0421708.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21283..21951
                     /gene="sdaAB"
                     /locus_tag="ACG8M1_000979"
     CDS             21283..21951
                     /gene="sdaAB"
                     /locus_tag="ACG8M1_000979"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFQ0421709.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            21964..22836
                     /gene="sdaAA"
                     /locus_tag="ACG8M1_000980"
     CDS             21964..22836
                     /gene="sdaAA"
                     /locus_tag="ACG8M1_000980"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFQ0421710.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(22927..24027)
                     /locus_tag="ACG8M1_000981"
                     /pseudo
     CDS             complement(22927..24027)
                     /locus_tag="ACG8M1_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(24119..25006)
                     /locus_tag="ACG8M1_000982"
     CDS             complement(24119..25006)
                     /locus_tag="ACG8M1_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0421711.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(25083..25628)
                     /gene="nusG"
                     /locus_tag="ACG8M1_000983"
     CDS             complement(25083..25628)
                     /gene="nusG"
                     /locus_tag="ACG8M1_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFQ0421712.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25729..25899)
                     /gene="secE"
                     /locus_tag="ACG8M1_000984"
     CDS             complement(25729..25899)
                     /gene="secE"
                     /locus_tag="ACG8M1_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFQ0421713.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(25923..26075)
                     /gene="rpmG"
                     /locus_tag="ACG8M1_000985"
     CDS             complement(25923..26075)
                     /gene="rpmG"
                     /locus_tag="ACG8M1_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0421714.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26237..26881
                     /gene="cbpA"
                     /locus_tag="ACG8M1_000986"
     CDS             26237..26881
                     /gene="cbpA"
                     /locus_tag="ACG8M1_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFQ0421715.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(26937..27440)
                     /locus_tag="ACG8M1_000987"
     CDS             complement(26937..27440)
                     /locus_tag="ACG8M1_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFQ0421716.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27453..27499)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            28037..29002
                     /locus_tag="ACG8M1_000988"
     CDS             28037..29002
                     /locus_tag="ACG8M1_000988"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0421717.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(29101..30273)
                     /locus_tag="ACG8M1_000989"
     CDS             complement(29101..30273)
                     /locus_tag="ACG8M1_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421718.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(30260..31405)
                     /locus_tag="ACG8M1_000990"
     CDS             complement(30260..31405)
                     /locus_tag="ACG8M1_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421719.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31419..32343)
                     /locus_tag="ACG8M1_000991"
                     /pseudo
     CDS             complement(31419..32343)
                     /locus_tag="ACG8M1_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32460..33539
                     /locus_tag="ACG8M1_000992"
     CDS             32460..33539
                     /locus_tag="ACG8M1_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0421720.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33536..34164
                     /locus_tag="ACG8M1_000993"
                     /pseudo
     CDS             33536..34164
                     /locus_tag="ACG8M1_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(34274..34501)
                     /locus_tag="ACG8M1_000994"
     CDS             complement(34274..34501)
                     /locus_tag="ACG8M1_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0421721.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(34604..37192)
                     /locus_tag="ACG8M1_000995"
     CDS             complement(34604..37192)
                     /locus_tag="ACG8M1_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFQ0421722.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(37212..37871)
                     /locus_tag="ACG8M1_000996"
     CDS             complement(37212..37871)
                     /locus_tag="ACG8M1_000996"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0421723.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(37920..38423)
                     /gene="trmL"
                     /locus_tag="ACG8M1_000997"
     CDS             complement(37920..38423)
                     /gene="trmL"
                     /locus_tag="ACG8M1_000997"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFQ0421724.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(38644..39510)
                     /locus_tag="ACG8M1_000998"
     CDS             complement(38644..39510)
                     /locus_tag="ACG8M1_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFQ0421725.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            39619..40260
                     /locus_tag="ACG8M1_000999"
     CDS             39619..40260
                     /locus_tag="ACG8M1_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFQ0421726.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(40322..41683)
                     /gene="mgtE"
                     /locus_tag="ACG8M1_001000"
     CDS             complement(40322..41683)
                     /gene="mgtE"
                     /locus_tag="ACG8M1_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFQ0421727.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(41701..42600)
                     /locus_tag="ACG8M1_001001"
     CDS             complement(41701..42600)
                     /locus_tag="ACG8M1_001001"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0421728.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(42602..43399)
                     /locus_tag="ACG8M1_001002"
     CDS             complement(42602..43399)
                     /locus_tag="ACG8M1_001002"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFQ0421729.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43377..44081)
                     /locus_tag="ACG8M1_001003"
     CDS             complement(43377..44081)
                     /locus_tag="ACG8M1_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFQ0421730.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            44212..44787
                     /locus_tag="ACG8M1_001004"
     CDS             44212..44787
                     /locus_tag="ACG8M1_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFQ0421731.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            44905..45582
                     /locus_tag="ACG8M1_001005"
     CDS             44905..45582
                     /locus_tag="ACG8M1_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFQ0421732.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(45661..47469)
                     /gene="pepF"
                     /locus_tag="ACG8M1_001006"
     CDS             complement(45661..47469)
                     /gene="pepF"
                     /locus_tag="ACG8M1_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFQ0421733.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(47645..48643)
                     /locus_tag="ACG8M1_001007"
     CDS             complement(47645..48643)
                     /locus_tag="ACG8M1_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFQ0421734.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(48869..49522)
                     /locus_tag="ACG8M1_001008"
     CDS             complement(48869..49522)
                     /locus_tag="ACG8M1_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFQ0421735.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        14907 a        10467 c         8757 g        15701 t
ORIGIN      
        1 atttgcttag catttttttt cattttagca cttccctgga attgctccac ctaaaaaacc
       61 acctatagac attcctgcaa tacaagtagt tgccttggcc caatcgaccg tacatttatt
      121 tttagtgcaa tacactccat ttccataata ttttccacta tgagtggtac ccccatagat
      181 aagttgtgtc tctttaatag acaaaatttt taaatgtttc ataatctaat cacccctaaa
      241 ttaatgtttt tagactatta ttctaacatt cattaaattt caaaaaacaa ttccttcttg
      301 aaacgtagca aaataattcc tgaataagaa tttaatcact tttaagtata taaactatgt
      361 atattcttta atattttttg agaatgcact tcgtacataa taaactttaa tcacattagt
      421 ctttcatacc tacgatcgat ctctttgact cgcacccata aattcataat agtttgtcgg
      481 cgtctttgga cgtttcgaag atgagctacg cattctcttt ttttatagac aaaaaagata
      541 gagacgaaca tggagcttcc aaatttggat atttgatcca attttggaag ctccatttat
      601 ttcgtgtctg tctttttatt ttttccagct ttcgactaat tcttggttct ctttgatcca
      661 gtcttttgct gcttgctgtg gatcttttcc attgttgatt tccaacataa ctttttccat
      721 atctttttct gaccaatgga aattgtctaa tactttgtaa gcttctggct ggtcttcttt
      781 caatcctttt cgaaccatcg tatggatctg ctcttcgctt cccattccgt tttcaggatc
      841 ttctaagtat ttcagatcat atttggcaaa catccaatga ggtgtccatc ctgtaactac
      901 aattggttcg tgttttttga tcgcttgacc tagtgcaacg gtcattgctc ctgaagaaga
      961 tgtctctact ttccagtctt tcaagttgtc atatttttgg atcgtgtttt cagcagccgt
     1021 aactacacca gctcctggct cgattcctat gattttctta cctgcctgat cggttaactc
     1081 atcgatcgaa tttacatcca tgtaggctgg cactgctaaa ccaacttttg ctcctgtcaa
     1141 attggcacct aggtcttcga cttgatcttt atattgtgca tattgtgaac catgagtttt
     1201 aggtagccaa gctgaaacca tggcatctga ctcgccattt gaaacagatt tccacatgat
     1261 tgaattatct aatggcgtca tcgttacatc atagcccatt tgtttcaata cttcaccgac
     1321 tacatttgtt gaagcaactt ctgtatccca ttcaacataa gataagttga tacgttttgt
     1381 ttctttggca gatgaaaaac tccctatacc aatcgcacct aagatcacta ctactacagc
     1441 accaatgatc agtccttgac gttttttact tttctgtgtt gttgctcctg cagctttttt
     1501 attgtttggc tggttcaaat gctgtgtaaa acggtcaatg atgattgcta agataactaa
     1561 tgcaaccccg ttgacaaatc cattcccgac ttgtgctctt tgcaatgctg ataatacgcc
     1621 gcgtcctaag ccgggtgcac cgatcataga ggcaataacg accattgaaa gtgacagcat
     1681 tgttgtttga ttgatccctg ccatgatcgt acttttagct aaaggcaatt ctagtttgaa
     1741 tagtttttga cgacttgtgc tcccgaatga atcagaagct tctactaatt ctttaggaac
     1801 ttgtcgaatc cctaaattcg taaaacgaac ggttggtggc agagcaaaga tgactgaggc
     1861 aaatacccct ggaaccatcc cgataccgaa aaatgcaact gctggaatca aataaacgaa
     1921 tcctggcatt gtctgcataa agtcaaggat cggtttgata atactttggg ctttactgct
     1981 ttttgccatc aagatcccta atggtacccc aatgatgatc gagatcacac tagataaaag
     2041 aacaagtgtg acagtattca tcaaatcatt ccatagacct tggttataaa taaaccatag
     2101 accgattaat gtgaacaacg taagtcctgg acgtttctta gaaataaaga aagctgctac
     2161 cgtcaataac aagataaaca aaggagctgg aatcactaac agtaaatttg taatccccga
     2221 catcactgcc tgtccaatcg tttgtaaaaa tgaaaatagg ccagaaaaag ttgtcgtaaa
     2281 ccattctgtg atattttcta cccagtttgc cactggtaat tgatagttca atagattatt
     2341 catgttcact cacctcgctt gtttctgcta atgcttcaat cacactacct cggatgacga
     2401 caccttttaa ttttccatcc tctacaactg caagtggagt cggtgagtca taaataatat
     2461 tgaaaatatc acttaccacc atgtctttcc caatcaccgt cacattttca tctaggaagt
     2521 cgatcaatgg acgtttttgc ttcctagctt ctaacgcttg atctgcagtg atgatccctt
     2581 tcaggtgtct ctttctgtca acagccatca gcatgctgac ttcttcatta cgcatccttg
     2641 tcaatgcaac gtttggtcca tcagattcga tattcgtcgt caatgcaggt accatgatgt
     2701 tttgagccgt aagcactttg gaacgatcga cttcttccac aaattcacgt acataatcat
     2761 ttgctggatt ggtcaatatt tcttcacctg ttccgatctg catgatttcg ccgtctttca
     2821 tcaaggcgat tctgtcccca atccgtaaag cttcattcaa atcatgggta atgaaaataa
     2881 tcgttttttg aacattggct tgcaggtcca gtaattcgtc ttgcatttct cgccggatca
     2941 gcggatcaag agccgagaac gcttcgtcca tcagcaagat ctcaggatca tttgctaaag
     3001 ctctggctag gccaacccgt tgttgcatcc caccagataa ctgactagga tattggtctt
     3061 taaatgaaag caaactagaa ttttctaatg ctttttctgc tttttcttgt cgttcttctt
     3121 taggtacacc acggacttct aacccgtatt ctgtattttc caagatcgtt cgatgtggaa
     3181 acagaccgaa gttttggaaa accatattga ttttatgacg acggacttct cgcaattctt
     3241 ctttgcttaa cttcgataca tcttctccat caatatagat actgcccgaa gttggctcaa
     3301 tcagacgatt caatagacgg atcaatgtgg atttcccact cccggaaagc cccatgatca
     3361 cgaagatttc tccttctttt acgtcaaaat tcacgtcata cacaccaacc gttgcaccgg
     3421 ttttctttaa aatctccgtt ttcggctggt gatcattcat catatctaaa gcggcttgtg
     3481 tctttttacc aaatatcttt gttaaatgtt ttacttctac ttttaccaaa caaattctcc
     3541 ttttttatgt aaattcattt ttctttctga aaaaagtgac cacactatgt taacatcatg
     3601 tagtcacttt gtcaaaaatg aaagaaattt gcttgtccaa actgaaaaaa acttggctaa
     3661 atctttgtaa ataaaaggtt tagccaagtt aatatttttt taatatttca cacaatcatt
     3721 ctgcaagctg atgctccggg taaaaaaagt ttgtcatacg ctgtagtgta tattcatttc
     3781 caataaaatg aacgatgtcc cctgccgtaa atttagcata ggggccaggt gaaacaagca
     3841 gttcttcatt atgagaaatt gcgataactg tggcgccagt cgcctgccag atattcaact
     3901 cgctaattga acggtccaga tgcattgctt tttctgataa agataattca aacggaagta
     3961 aaggattcat cttatgtatt cgcttcgctt gattgaccag ctgatccaat aattgagaaa
     4021 aatgattcag ctcatcttgt tgcttctcca cacttgccat gatttctgct tttgtatctt
     4081 ggatggattg tacatcttga tattgcaata ggaaatcttt tgctttttcc ttcgaagcaa
     4141 caaatgcccc acttccatgc cgtacttcca tgattccaag atctaccagc acattgatag
     4201 ccttgcgggt agtctcagga gaagcattgt acgtactggc aagtgttgag cgggcatgga
     4261 tcttctcacc cactttatat cggttttcaa cgatacgttc ggctaaatca acagcaatct
     4321 gctggtagcg cgggcggacg atttttttct ttccagacat tttctttcct ctttcttttt
     4381 ttactttccc tcatcttact atgctctagc aaaataagca aaaaagggga gaatagcctc
     4441 ttgcaacgac tgatcatcgc ttgatctgtt ccttttttac tgggcaagct gtttgacagt
     4501 catcacaatt cttaccggat tttaaacgag tatagacaat tgcgcctgca cttccaaaga
     4561 ttaacacact taataagaat gtcgccatcc tattcctctc cttctaatga caatatagta
     4621 taaaactggt tcttggattt tggctgacgg aacaaaacat aaacgagtcc tatcatcagt
     4681 aaaatagcaa gatacgtccc taacgctacc tgtccaccct ccaataagtg tcccaactga
     4741 taaatcacaa aactaactaa ataagctaaa ccgcattgat agcctatggc gatccaagtc
     4801 catttcttgg cattcatttc ccgatggata gccccaattg ccgcaaaaca aggcgcacaa
     4861 agtaaattga aggctaacaa tgaataagct gctgcgggag tatatgtgtg ttgtagcact
     4921 tgccagattt ctctgccatt ttcggatact tccgcatgac caaacaaaat accaaatgtg
     4981 ccaataatat tttctttagc gaccaatcct gtaatcgctg cgactgttcc ttgccagttt
     5041 ccccaaccaa gcggctgaaa aacaactgcc aggattcgcc cgaaaaaggc taagatactt
     5101 tggtcttcag aaacaggttg agcataaaaa ttataagaag agctgaacca gatcacgata
     5161 ctagaaacaa agataatcgt tcctgctttt ttaacaaaag acttgctgcg gtcataggtt
     5221 tgtcttagga ccgctgacca ttgaggaaaa tgatatgcgg gcaattccat gataaaagga
     5281 gctgtatctc cagcaaacaa acgtgttttt ttcaagctga ttccagagaa aataattgca
     5341 gtcataccaa gaaaataggc agaaggagct acccaagatt gatgaggaaa aaaggcccct
     5401 gctactaagg caataatcgg caactttgca gaacaaggca tgaaggttgt gaccatgatc
     5461 gtcaaacgac gatcttgctc gttttcaatc gtgcgactgg ccatgacgcc tggcactcca
     5521 catcctgtag caatcagcat aggaatgaag gattttcctg aaagaccgaa tttcctgaaa
     5581 agtcgatcca tgacaaaagc gatcctcgcc atatatccgc agtcttccag aaagctcaag
     5641 cataaaaaca atataatcaa ttgcggtaga aatcctaaca ctgctcccac gcctgcgatg
     5701 atgccgttca agatcagctc ctgcatccat cccgctactt gccattcagc taacaatctg
     5761 ccaacatgtt ctggtaacca tgtaccaaac aatgtgtcat tgatccaatc tgtccccatt
     5821 gttcctactg tttgaatagc cagataatag atcagccaca tcacaaatgc gaagatcggc
     5881 aaggctaacc aacgattcgt tgcaatctga tcgattttgt cactcatcga taattggaaa
     5941 gaatcatttg acacaacaca gagtgtacat agttgggtaa taaattcata acgttcattg
     6001 accagaatcg tctcactatc gtcgtccaat agtttctctg ttaactggat cagttgctcg
     6061 atctcttttt gctgagaaac tgctatctcg taatcctctc ttaccttctg atctcgttca
     6121 aaatatttca ttgcatacca gcgtttcttg ccgctttgtt ctcctagtac atcttcaatt
     6181 tcatgtaaag ctgcttctaa acgtggatca tatgtacagg gaacaggaat agaaggccgc
     6241 ttttttgcag actcctgaat cttttcgatt agtttttcga ttccttgctt tttcaatacg
     6301 ctgattggta aaactggtac accaagacca taggaaagct tttctagatt gatttttttt
     6361 ccttcttttt tgatgacatc catcatattc agaccaatga tcataggaat gtctaaatcc
     6421 aataactgcg tagttaaata aagatttcgt tctaaattgg tagcatcaat aatgttgatg
     6481 atcagttcag gctgttcctg aaccaaataa tctcttgcaa tcacttcttc tggtgtataa
     6541 ggagacaaag aatagatgcc gggtaggtcc tgaatatgaa tgttcggatt ttttttcaac
     6601 gatccttctt ttttttctac tgttacgccc ggccaattcc ctacatattg attcgaacca
     6661 gtcaagagat tgaacaagct agttttcccg ctgtttggat ttccgactaa cgcgatattc
     6721 attctttttc ctccctttgt atcaagatta gttcggcctc tgactttcgt aacgtcagtt
     6781 cataccctcg cactgtcagt tcgattggat ctcccagagg ggctagtttt cggataacta
     6841 tttttacatt tcgcgtcaat cccatatcca ttaaccgtcg cttcactgcg ccttgtccgt
     6901 ggattgctac gacgatccca gtctctcctg cttttaattg atcaagagaa gtccagcttt
     6961 cagaggaagc agtcttttta ttgacaaaga tttgacctag tatttcccga cttactgcca
     7021 ctcgatgact ttttaccagt aaaatggcat tgttgcctga taaattgacg acgacgattt
     7081 tacttccggc aacgatcccg atattttgca aatggcgttt tgttttttct tctgtttcga
     7141 ttcgttcgac ttgataaacg aaattctgct ttgcctgcgc taaggtctgc atattgattc
     7201 ctctcttgtg aaataaatca tgtattaaaa tcattcatta tatgttctaa ttttcttacg
     7261 tgttacgcaa ataaatgaga atcattctca catagaatac tctcggtaat tgagaatgtc
     7321 aattatactt gtgatattat gagcgaatct ttagtattga tagataaaaa tgagaaaaaa
     7381 atatttcttc atagttttcc acaatttttt ctctattaaa tttgctattt tcccacacga
     7441 tacttgtttt cagctctttt ttcaaaaaca caaaacttag tattccacag tttccacaac
     7501 acaatatgta gtgtttgttg tttgactttt ttactaagag ttttatacta tctattatag
     7561 ataataagaa tgtgttagag gaggcactca ccatgaacgt aaaaatcttt tctaaaaata
     7621 attgtatgca atgtaagatg gtcaaacggt ttttaacaga aaatcaaatt gcttttgaag
     7681 aagtcaatat cgatgaacag cctgaagcag tagactggtt gaaagcacaa ggattccaaa
     7741 gtgttcctgt cattacttct gatgcagaaa cagttatcgg attccgtcct gatcagttgc
     7801 gtaaacttgc cagctaacat gactaaaaga atcaaaacgt gatacatgga tttgaagggc
     7861 ttgagacagc accagttttt gtcgcaaact tccaaatcct tttttaaagc ttaaaaacaa
     7921 tgcaatgatt tgcaatcaag catcatcaaa tacgaaatga aggttgggcg tacgtatgag
     7981 tcttaaaaat ttacaagatg tcagttattt caagctgaat aatgaaatca atcggccagt
     8041 caatggtcaa atccctttga ataaggataa agaagcttta gttgcctttt ttgaggaaaa
     8101 tgtcaaacca aatacgatga cttttctatc tattatggaa aaaatcaatt acttgatcga
     8161 tcaagaatat atagaagcag aattcattca attgtattca ccatcattta ttgaaaagct
     8221 atatcaattt ttggacgagc aacatttttc tttcaaatct tttatggctg cttacaaatt
     8281 ttattctcaa tatgcgttga aaaccaacga cggttccgct tatctggaaa cttatgaaga
     8341 tcgagtagcc ttcaatgcgc tttactttgc gaacggggat gaagaattag cacttgctct
     8401 tgcagacgaa atgatccatc aacgatatca gccagctaca ccttctttct tgaatgctgg
     8461 acgtaaacgt cggggcgaat tggtgtcttg tttcttgact caagtcactg acgatatgaa
     8521 ctctatcggg cgctcaatca actctgcttt gcaattgtcc cgtattggtg gcggcgtagg
     8581 gattacttta tcaaatcttc gtgaagccgg cgctcctatc aaaggatatg agggtgctgc
     8641 aagtggtgtc gttccagtca tgaaattatt cgaagatagt ttcagctatt ctaatcaatt
     8701 aggtcagcgt caaggagctg gcgtggttta tttgaacgtt ttccatccag acattattgc
     8761 tttcctttca gcaaaaaaag aaaatgcaga tgaaaagatt cgcgtaaaaa ctctttctct
     8821 tggcgtgatc gtacctgata aattttatga attgacacgt aaaaacgaag atatgtattt
     8881 atttagtcca tatagtgtcg aaaaagaata tggtgtccca ttctcttatg taaatattac
     8941 agctgagtat gatcatctag ttgcaaatcc aaacattcgc aaacaaaaaa tcaaagcgcg
     9001 tgatcttgaa aatgaaatct caaaattaca acaagaatct ggctatcctt acgtaatcaa
     9061 tattgataca gcgaaccgcg agaatccaat cgatggcaag atcatcatga gtaatttatg
     9121 ttcagagatt ttacaagttc aaacgccttc tgtgattaac ggcaaacagg aatatgaagt
     9181 attaggaacg gatatctcat gtaacttagg ctcgacaaat atcgtgaatt tgatgcaaag
     9241 ccctaacttt ggtcaatctg tgcgtacgat gactcgtgca ttgacattta ttacagatgc
     9301 atctgatatc gatgtcgtac caccgatcca aaacggaaat aagctgaatc atacgattgg
     9361 attaggtgcc atgggcttac acacttatct tgcaaaagaa caaatggaat atggctcaga
     9421 ggattcatta gactttacaa atatttactt catgctgttg aattattgga cacttgttga
     9481 aagcaacaat atcgctcgtg aaagaaaaca agttttccat aattttgaaa aatcagctta
     9541 tgctgacggc acttatttcg aaaaatacgt aactggagaa ttccagccaa aatcagaaaa
     9601 agtcaaagca ttgtttgaag gcatttttat cccaactgct gaagattgga atgctttgaa
     9661 acaagcagta atgaaagatg gactgtatca tcaaaatcgc ttggcagtag caccaaatgg
     9721 ctcaatttca tatatcaacg atacgagtgc aagtattcat cctatcactc gcatgatcga
     9781 agaacgccaa gagaagaaaa tcggtaaaat ttattaccca gcgccttatc tatccaatga
     9841 gacgattccg tattacactt ctgcttatga tatggacatg cgtaaagtaa tcgatgttta
     9901 tgcaatggca caacaacacg tcgatcaagg catgagtttg actttattca tgcgttctga
     9961 aatcccagaa ggcatttatg aatggaagac aacaacgaag caaacgacac gtgatttgaa
    10021 tattttaaga cattacgctt tccacaaagg aatcaaatcc atttattacg tacgtacctt
    10081 tactgatgat gcagaagaaa tcggaagcaa tcaatgtgaa agctgcgtga tctaatatca
    10141 tagatagatt cgcttattca tattttaatt aaaggagcat tctcatgtca gaaacatatt
    10201 atgaagcaat aaactggaat gaaattgaag atatcattga taaatccact tgggagaagc
    10261 tgacagagca attttggcta gatacacgta tcccactttc aaatgaccta gatgattggc
    10321 gtacattgtc tcaattggaa aaagatacag taggacatgt atttggcggt ttgacactgc
    10381 tagatactgt ccaatctgaa agtggcatgg atcagttgcg taaagatgtc cgcactcccc
    10441 atgaagaagc cgttttgaac aatattcaat tcatggaatc cgttcatgcc aaaagttatt
    10501 cttctatttt tagtacactg aatacgaaaa aagaaatcga agaaattttt gactggacaa
    10561 atacgaatcc ttatctgcaa aaaaaagctg agcgtatcaa tgaaatctac aaacacggta
    10621 caccgctaga aaagaaaatt gccagcgtct ttttagaaac attcttgttc tattcaggtt
    10681 tttatactcc tctttattat ttaggaaaca acaaattggc taacgtagca gagatcatca
    10741 aactaatcat ccgagatgaa tctgtacatg gaacctacat cggttacaaa ttccaattag
    10801 gattcaacga gttacctgaa gcagaacaag aaacgttaaa agactggatg tacaatcttc
    10861 tttatgagct ttacgaaaac gaagaacgtt atacagaaga attatacgat ccaatcggct
    10921 ggacagaaga agtcaagaca ttcctacgct ataatgccaa caaagcattg atgaacctag
    10981 ggatggatcc actctttcca gatactgcca atgatgtcaa cccaatcgta atgaacggga
    11041 tttcaacagg cacaagcaac catgacttct tctcacaagt cggaaacggc tatttgttag
    11101 gtcatgtaga agcgatgaaa gacgacgatt atttgattgg attggaataa ggatttattt
    11161 taattcaaaa atttttcgaa aaataaaaag agtttagcgt acagatattt taaatgtaca
    11221 ctgaactctt ttttatgctt attcacttgt ttcttccagc acttttggac tgtctaactt
    11281 ttccgaaaca tgttccattc ttctcaataa atagattttc cggatattta atattatcgt
    11341 cttaatcact gcatagacag gtatgcaaat cagcatgcct aatattcctg cgacacttcc
    11401 tgctccaatc aataccaaga tgatcgtcaa aggatggata ttcattgatt tcccaaataa
    11461 caacggcttg atcaaatttc catctaattg ttggatcact aaaatcgaca acgccatata
    11521 caaagcttga aatggagaga taaacaaacc gacaatgatt gctggtaccg ctccaataaa
    11581 agggccgaca tacgggataa tattcgtgat tccgcaaatg accgcaagca acaagctata
    11641 aggctgatcg aatattctca ttgccaaaaa gctcattaca ccaataatca aagcatctaa
    11701 gatcgtactg ctgatatagg cagataatgt ttcgtttaat tcttttaccg tttggcgtaa
    11761 ctctttacga atcgctttcg gaaagaagtg agacaacgca tcaataaatt tgtgcccatc
    11821 cttgaacata aatagcaaaa taaatggaac ggtaaataac aaaataaaaa attgcatcat
    11881 aaatgaaatg atttttgaga cacttgcaga taaactgact aatatgatat tgaacaaatt
    11941 actaagagat aaatttgctg atgctaattg ttcttccaaa ttgaaatttt taaactcttc
    12001 ccgctgcgcc aattcattta accatttgct tgtttcatct gcatacattg gcaagctctg
    12061 ggtcaattga attgtctgtt ccattaactg aggcactaca ttcatgacag ttaaaacaac
    12121 taaaatgatt acgaccaaaa acgtcaataa aaaaccgaac actctcggga tccgatgctt
    12181 ttcgagaaaa acaacgattg gatcgaacat ataatagata aaaccagcaa caagcaatgg
    12241 taaaaaaact gccgaaagca ttttcaatat tggactaaaa atattcggca tttgtaaaat
    12301 aaagtacacg ccgatgatcg tgagtactag ctccactgtc cagaaaaata attttgattg
    12361 tttaaaacgt gattgcatac atctcctcca aggtcctttg atacttctat tctatcattt
    12421 aacaaagagt tacgcgctga gattttcatt tgcttaaaaa aaacaaaaaa aataaacata
    12481 ttttaatgag tagacgagta cttaaacaaa aacacggttt ggagtagtga caaaaattat
    12541 actgcagtcc ctttttccaa ataaacggtg ttcaaaagct tgcatcttcg taataagccc
    12601 agccaaacga aaaatataag gaactatttt tatttggctg ggcttattac ttgatgtagg
    12661 acatctattt tacaacctca gatcatttat tgcgcaatac tgactaaatg caactttgtg
    12721 atatttttgt gtacggacaa ctcctcgatc acatcggcat aagtgagccc ttttggaaga
    12781 tcaatcgtat agatattttt gtacactcgg tagtcatcaa cgaattttac gtcaaaattc
    12841 acatcttcga ttacgatatt tttctcttca aaataatcgg taagaaaatc tttggtttct
    12901 tttctatgga taaattggat ttctaacttt ttagtcgtag gtacatggat cacgcgtttc
    12961 actactgtga gtgcaatagc aatcccgata aaactgatga tcgcaatgga atagtaaccc
    13021 atgccgatgg cgatccctaa tccagcaatt gcccataaag aagcggcagt cgtaagtccc
    13081 gtcaccgatt gtttcgtgac gatgatcgtt cccgcgccta agaaaccgac accactcacc
    13141 acttgagcaa tcagccttgc ttcatctgaa cgaatcgttc cagcaagctg tggatactct
    13201 aaagcatctc ttaatgcacc actagcgatc tcaacttgga tcaatgcaat gatacatgct
    13261 cccatacaaa ctaaaatatg cgtacgcata cctgctggac gatttttata ttgtcgttca
    13321 aaaccgattg ctccgccaaa tagcatagcg atccctaaac gtaaaataat ctctggaatt
    13381 gtcaatacca tatcattcat ctaaacaccc tccagtccaa tatatcatgt ctgaaaggag
    13441 cagacaaaaa aagtgcaatt tttacctctt acgaaaaaag gactgtgaca aaatttttgt
    13501 catagtcctt tttatgaata aacggtgttc aatcagctga ccctcggtat tactcaacaa
    13561 acggcaaaat atggggagct atttttcctt tgtcttctct aatactcagg tcaaaacgct
    13621 gatttcacaa cctctttagc ctactattga aaattacaac ttacttgctg cttcttcatc
    13681 gatgatcaca acaacattgt cgtgattttg caatacactt gctggcaaat gattcgttac
    13741 aggtccttca atcatccctt tgattgcatc agctttgctt tcgccaaatg ccatcaagac
    13801 gatttcttta cttttcataa ttgaaccgat tcccattgaa acagcttttg ttggtacatc
    13861 ttctgcttta tcgaagaatc gtttgtttgc attgattgtt gattctgtta agtcaactac
    13921 tgaagtcgtt ccgtcaaatg aagcaccagg ttcattgaaa ccgatatgtc cattttgccc
    13981 gattcctaag atttggatat cgattggatg tgcatcgatg atttgatcat actttttgca
    14041 tgctgcttcc agatcttctg cttttccatc tggtacaaac gtttctttga atggtttttt
    14101 atcaaataat tggacatcca tgaaatgacg gtagctttgt tcatctgaac cgcctagtcc
    14161 aacgtactca tctaagttta cagaagtcat ttcactgaaa tccaaatcgc ttgaagtcat
    14221 ttctttatat aaagtaactg gtgtgcttcc tgttgccaat cctaatactt ttgcaccttt
    14281 gttcatacct tctttgatga tttcaaatgc tttttttccg ccttcttcag cgttttttac
    14341 acgaatgatt tccatagtga ttgctccttt atattttggt atagcccaat tatagcattc
    14401 tttttttctt tttacaataa ttagtataga ccaaattgca tttttttcat tttcttgaca
    14461 ataaatagga atccgtgtta ggtttcataa gatggttcaa tcaaacaatc catgttgcat
    14521 gaaaaccaag caagtgattc actgtggacg ctttatgtct gcagtttttt tatgaaaaag
    14581 gagttattat gagtatactg acattaaaca acattaccca gcaatttggc gacaaaatcc
    14641 tctatgaagg tgtcgatctg caattaaatg ctggcgaaca tcttgggctg attggacaaa
    14701 acggagccgg taaaagtaca ttgattaaaa tcatcactgg tgagatctta ccagatgacg
    14761 gacagatcca ttggcaaaaa aatattcaca aaggttacct cgatcaatat gtggaagtcg
    14821 atgaaacatt aacaatcgaa gaatttctaa aaactgcgta cgcaaaagaa tacgaaaagg
    14881 aagaaaaaat tgcttttctt taccaaacat atagcgagac cttcgatgat tccttgctgg
    14941 aaaaagctgg gaaactccaa acggaattag accaaggagt gttttatcaa atcgacacct
    15001 tagttgctga gatgagcagc gggttgggga tcgatgtctt aggtttagat tcactgttga
    15061 aaaatctaag tggtggacaa cgttcaaagg tgattttagc aaaactactt ttagaaaacc
    15121 cagatgttct gatcttagat gaaccaacca atcacttaga tgatcagcat atccaatggc
    15181 tgacgcagtt tcttcaggat tttgacggtg cgtatatcgt gatttcccat gaccaagaat
    15241 ttcttgatca gatcaccacc catatcgcag acatcgagtt tggaaagatt actaagtata
    15301 ctggccatct aaaacaagca ttgaaacaaa aggaacaaaa tcgcgaaagc tatttgcgcc
    15361 aatatcatgc tcaacaaaaa caaatcgaaa agaccgaagc ttatattcga aaatacaaag
    15421 ccggttcccg atcaacgatg gcaaaaagcc gacaaaaaca attagataaa atcgaacggc
    15481 tgacgcctcc agcttcagca agtaaagctg tctttgattt tccattctcg cctattgtca
    15541 cgacattagc agtggaaaca actgatttag tcatcggata tgatcgaccg ctacttgcac
    15601 ccatcaattt gaccatccgc tttggtgaaa atattgccat tcgaggcttc aacgggattg
    15661 gaaaatctac tttattaaaa acactgatcg gtgagattga aaaaataagt ggcgatttcc
    15721 acttcccaga taacacaaaa atcaattact tttcacaaga tctgtactgg gaaaatccat
    15781 tagaaacacc actacaatat ttaagcagtc aatttccaaa agcgactatc aaagaattac
    15841 gtcgccaact agctaaagca gggttagtta atcaattagc aagtgaacct ctcactacat
    15901 taagtggtgg ggaacaaact aaggtgaaac ttgcacagtt gacaatgaac caaggtaatt
    15961 tactgattct cgatgaaccg acgaaccata tcgatcaaga aacgaaagaa agcttacaag
    16021 acgggataca gaaatttcca ggaacagtaa tcatcgtctc tcatgaacaa gaattttatc
    16081 aagatcttgt gcaacgagtc attgagattg aaccaaaata aacgtttgat tgaatagttg
    16141 aaaaaaagga gctgtgacaa aagttttgtc acaactcctt cttctgaata aatggtggcc
    16201 aattagctga ccttcggtat tagctcaaaa aacggcaaaa tatgaggagc tatttttatt
    16261 tggctattct tattacttga tgcagaacag cttttcacaa cctcttttcg tctatttttt
    16321 attttcgaga tttctctttc ctttaaaaac aactgtttga aagaagaacg cacatccttg
    16381 aaaaacaagc ccgctaaccg ttacacctaa ccagccatac tgctgccaca ttgtcgtccc
    16441 tagcaatgaa ccagccgcac ctccaataaa gtacataaac ataaatacag tattatttcg
    16501 gttgcttgct gcttcaccta gcccttgtac tcgtgtttga ttggcgactt gaccaaattg
    16561 attcccgacg tctaataaaa taatagctaa aagcaaaatg gccaaatggc ttccgccaac
    16621 caataaagca ataaagctta ttgtttgcat aacaagtccc atatacacga tttttctttc
    16681 agaataagaa tctgccagtc gtcccacgat aggtgcagca actgctccag acaaaccaaa
    16741 aatcgctaat atccctgctt cgaatgttcc ccaattgtag gcgggactgc tgatataaaa
    16801 aatcaacgta gaccaaaaga tcgaaaatgt tccaaacatg aaaaatccac tgactgccgc
    16861 ttctcttaat agacgttgag aagcaactaa atgcggcaaa cttttaagtg aatcaaggta
    16921 tgaaacagct gtactacttt gctggacaga acgcggcatt ttccagtaaa gcagaagtgt
    16981 aagaattccg actgcacata aagcaaataa atagatcatc cgccaagaaa aaagactggc
    17041 aacaatacca gataccgtcc gagaaagcaa aatccccacg agtaaaccgc taagcaatgt
    17101 acccatgacc ttccctcttg cttttggtcc cgctagtacc gcaccgtaag gaatgatgat
    17161 ttgcggcacg atcgaaagta atcctattaa aaaagaagcg catgcaaata acgtaaacga
    17221 aggcgcaaaa aaagcggcca acagagagac ggcagataac gctgccattc gaatgatcaa
    17281 ttttggacga tccaccacgt cccctaaagg aactaaaaac agtaacccta acgcatagcc
    17341 taattgggtc aacatcgtca atatcccgac tgcacttgtg ctaacagata aactagctgc
    17401 tacttttgtt ccaatcggct ggatgtaata catattggca acaacaacgc cacaagtgat
    17461 tgataatagt aaaataagcg aagttgttaa aggttttttt tcattactct tcattgattt
    17521 cccccatttc ctatcttagt ttacaactta tggaaaagat tggaaataga aaaatacaac
    17581 tattcgccac acttattatt tgtgcttttg ttttccttgt tttttcttgc gatctttata
    17641 aatgaagaca actaacccta ctagcacagt aacacttgca accaacgtga ctgcagtttt
    17701 gttatatccg tgaaacagag cttctccacc acacgcatac aacacagacg aagggatgac
    17761 tccaatcacg atcgacaata tgatttgctg tagaggcaat ttcatcgcat ctgcagcaaa
    17821 attgaccata gaagatggaa taaccggtat catatagcct aacattacac ctatttttgg
    17881 atgtttcatt tgtcggattg cttgcaccca atgattcgtt tcggttttct tatctaaaaa
    17941 ttttaagcga tgcataagga aaattgcagt gatgttacca agagcattac ccaaaatgtt
    18001 gatgatcgca cctgtcagtg gtccaaagct caaaccagca atgactccaa ctactgaagt
    18061 aggaatacct ggaacagcac acatcaccgc tgtcaatacg atcaagagta tcgatgcaaa
    18121 agtcccatgc gaacgaatat gtgcgagtag ctctgcctta ctcgctctcg gatttaaaaa
    18181 taattggatg tctgtctgat attctaaata caaccgatag cccactacca gtatcagaat
    18241 gattcccaac gagatcaata tcaatcggat tattttcttt ttcatatttc ctcctgaaaa
    18301 aaatctatat tcattaaata atagtttaac ataaaaacaa aaaagcaccg aaatccaaca
    18361 taggatctca gtgcttttaa atagtaaaaa ttatttaaca gttacagatg cgccaacttc
    18421 ttcaagttta gctttcaatt cttcagcttc ttctttagat acgccttctt taactggtgc
    18481 aggagcgcca tcaactacag ctttagcttc tttcaagcct aaaccagttg cttcacgaac
    18541 tgctttgata actttaactt tttggtctcc agctgcagtt aattctacag tgaattctgt
    18601 ttgttcttca gcagcagcag cgccaccagc agcagctaca gctacaggag cagcagcaga
    18661 tacgccaaat tcttcttcaa tagctttaac taggtcgtta agttctagga tagttgcttc
    18721 ttttaactca gcaacgatgt tttcaatgtt caatgccatt ataatttcct ccgtttaatt
    18781 gttctttttt atttaatgct ttatgcggca attaagctgc atctccatct tctttgtctg
    18841 ccactgcttt gacagcgtaa gccacgttgc ggactggcgc ttgtagtaca gatagcaaca
    18901 tagatagaag tccttcgcga tttggcaatt ttgccaatgc tgtgatttct tccaatgaag
    18961 agactttacc ttcgatgata ccgcctttga tttctaatgc ttttgcttct ttagcaaatt
    19021 cgtccatgat tttcgctggt gcgactacat cttcgttact gaatgcaaca gctgtaggtc
    19081 cagtgaatac ttcgtccatg ccttcaaggc cagctttttt agctgcacgt gaaagaatag
    19141 aatttttgat aactttcatt tctacgttag catcacgaag ttgtttacgt aaacgtgtta
    19201 cttcatcaac tgttaatccg cggtagtcaa cgactactac tgatgcagct gctgtaaatt
    19261 tttcgcttac ttcatcaacg attgctgctt tttttgcgat aattgcttca ctcatttttg
    19321 agtttcacct cctgaatttt gatggaagag ttttttgcac tgaaaaggca agtcactttt
    19381 atagttactt tgctcaacca gtattattca tcacctattc acttcgttca tagtgattct
    19441 actcgctttg ctcgaaagga aactcctttc gctttgctca accagtattg ttcatcatct
    19501 cttcacttcg ttcatagtga ttcacaataa aaaactctat gccaccgcag acatagaggg
    19561 actattgaat atattcaata aacgtcctcg gtaggaaatt aaggcttgat gccacctact
    19621 gtcttcggta caagttaatt attaacctca actagcttag catgctaaac tagttgagtc
    19681 aagaattatt tttcagttgg atcaatcaac attctaatat ttaattagaa agaagcttgg
    19741 tcaacatgga taccaggtcc aaatgttgtt gtgatcgtta catttttcat gtattgacct
    19801 ttagctgctg atggtttagc ttttagcaat acatcatgga ttgctgcaaa gttttcaact
    19861 aatttttcat cgtcaaatga aacttttccg attggtacat ggatatttcc agctttgtcc
    19921 acacggtaag ttactttacc agctttcact tcgtttactg cttttgttac gtccattgta
    19981 actgtaccag ttttagggtt tggcattaag ccttttggtc ctaatactcg tcctagacga
    20041 cctacagtag ccatcatatc aggtgttgca acaactacat caaagtcaaa ccatccgttt
    20101 tggatttttt gaaccatgtc gtcgtcacct acgaaatctg caccagctgc ttcagcttct
    20161 tttgctttgt ctcctttagc aaaaactaaa acagtttgtg ttttaccagt tccgtttggt
    20221 aatacaacag caccacggat ttgttggtct gcttttttag ggtctacgtt caaacggtat
    20281 gcaacttcaa ctgttgcatc aaattttgca atgtttgttt cttttgctaa agctactgct
    20341 tcggcaacag gataaacttt acttgaatca acttttttta atgcatcttg catttttttg
    20401 ctctttttag ccattttggt tcctccttga ttgtggttat aacggttgta cctcccacgt
    20461 gttctatatc tttcaatata gagccaactg agaagctgct gtcttagggt gtatagatta
    20521 ttctacagtg atccccatgc ttcgtgcagt tccttcaacc atgcgcattg ctgcttcaac
    20581 gttagctgcg tttaggtctt ccatttttaa ttcagcgatt tctcttactt gatcgctaga
    20641 aactttcgca actttatttt tgtttggttc gcctgaacct ttttcgattt tagctgcttt
    20701 tttcaataga acagcagctg gcggtgtttt tgtaacgaat gtgaatgaac ggtcttcgta
    20761 tacagaaata acaaccggaa tgatcaaacc tgcttgatca gctgtacgag cgttgaattc
    20821 ttttgtgaat cccatgatat tgatacccgc ttgacctagt gcaggaccta ctggtggagc
    20881 tggagttgct ttacctgcag gaatttgcaa tttaacgatt ttttctactt tctttgccac
    20941 gagacatacc tccttaagtc cgtgatgtgg ttaattggag atgcatattt ctcctcccac
    21001 gttttatctg atctgaaaaa atccagacaa ataatgtgca aaacaatgca cactggtaca
    21061 gtatagcaaa tttatttgtt ttttcaagat ttttttctgc tatttttaca ttttgcttga
    21121 ataaacgcta aatttattct aaaaaaacaa caatttttcg ttctcatttc ttcttttatg
    21181 ttacacttgc gctagcatgg ttcaacagat gaaagcaaac aataacacgg ttttttagac
    21241 ccttgtacaa agattcctac ataacaaaat gaggtggaga aaatgaaaga tttaaggtat
    21301 agaagtgtct ttgatattat tggacctgtg atgattggtc caagtagctc tcacactgcc
    21361 ggagctgcta gaatcgggaa aatcatacgt agtatatttg gcgaacagcc tgattctgta
    21421 gatatttatc tatatgaatc atttgcaaaa acctatcggg ggcacggaac agatattgca
    21481 ttagttggcg gcctgttagg gatggaaccc gatgatgaac gtttagctga ttctttgaaa
    21541 ttggcatatg aagccggtat ggaagtcttg tttgttccta agagtgaaaa agccgaacat
    21601 ccaaactctg taaagatgct tctaaaaaaa ggaacacgaa agctttcagt cactggcatt
    21661 tcgatcggcg gtggcaatat ccagatttct gaattgaatg gattcaaaat ttctttaagc
    21721 atgggtactc ctaccttgat cgttgtccac caagatgttc caggtatgat tgctaaagtg
    21781 actagtatac tttctgagac caatacgaat atcggcacta tgacagtgac acgggaatca
    21841 aaaggtgaaa atgccattat gataattgaa gtagatgatc ctcaagtaga agaaacggta
    21901 aaaagactca aacagctgcc aaatatcgac agcgtaaatt atttcgatta aggagctaaa
    21961 aaaatgtttt tatcgattga agaattagta gatcaagcaa aagcttatcc aagtgtagca
    22021 gaattgatga ttgcagttga aatggaaatg agtggccgtt cccgtagtca catcatcgag
    22081 atcatggaaa aaaacctctc agtaatggaa caatcaatca acgagggaaa agaaggtgtt
    22141 acctccgtca caggaattac cggtggtgat gcaaaaaaat tagatgatta tttaaatgag
    22201 gcagactttt taagtggaga aacaatctta aaagctgtac gcaatgctgt agctgttaat
    22261 gaagtcaatg caaaaatggg gttgatttgt gctacaccga ctgccggaag cgcgggtgtt
    22321 gttcctggtg tgctgatggc tgtccgagat cggcttgatt tgacacatga acagcaattg
    22381 gaattcttat ttaccgctgg cgctttcggg ttagtcatcg caaacaacgc ttctatcagt
    22441 ggtgcagaag ggggatgtca agcagaagtt ggttctgcaa gtgcaatggc agcagcagct
    22501 ttggtttgtg caaaaaatgg gactcctcat caagcagcac aagcagtagc cattacattg
    22561 aaaaatatga tgggactgat ttgcgatccc gttgcaggct tagttgaagt cccgtgtgtc
    22621 aaacgtaatg ctttaggctc ttctcaagct tttatctctg ctgatatggc attagcgggt
    22681 atcgaaagtg tcattccgcc ggatgaagtc gttgctgcaa tgtaccaagt cggacgtcaa
    22741 atgccgtcga ttttcaaaga aacagcagaa ggtggcttag ctgttacgcc aactgctaaa
    22801 cgacttgcgg aagagatttt aaataagagg gcgtgataaa gctccttaat ttcgagtatt
    22861 aagagattag ttatcttcat aacaaaaaac gaagagagga ctaattgccc ttctcttcgt
    22921 tttttattaa tccatcaatt tcgtattttt tacttcatcg atcgtttttg ttcctgcaag
    22981 ttgcatcgtg atcgacaatt ctttgttcag gtgttcaaaa acagatgtta ctccttctgc
    23041 cccacctaga ttcaacccat aaatcactgg tcggccaatc gcaactaagt cagcaccact
    23101 tgccagagct ttgaagacat gctctcctcg acggacacca gagtcgaaaa tcactggtac
    23161 acgtttgttg actacttcgg caatttttgg caatacttca aaggacgcag gacctccatc
    23221 tagttgacgt ccaccatgat tggataccca gataccatct gcccctgcag agatagcgat
    23281 tactgcatct tctggcgatt gtattccttt tacgataact ggaagatggg tgatttcttt
    23341 gattgttttg atgtcatctg gtgtcaagcc ttgttttgca gctgcataaa tttctgcgat
    23401 tccttttcct tcgccattac cacttgcact ttgttcgcta tacgcagcta agttaggcat
    23461 tggtaatgga aattggaatt gattgatgac gtcttcttca cggtaaccac cgagcgttga
    23521 atctgccgtt aaaatgatag ctttagcccc tgcttctact gctttgttca aaatgaactc
    23581 attgaatctg tcgtctttac tcatatataa ttggaaaaac tgcggtgcgc ctggcgctgc
    23641 atcggctgcg tctttgattg tcgtatttgc ataagtgctg atggaaaaga ttgatccagc
    23701 agcagctact cctttagctg tatcagcttc ccctttttca tgtgccaatc cttgggccgc
    23761 tgatggcgct tggataatcg gtgtatctaa ttcaattccg aaaacagatg tatgcaaatc
    23821 ggctgagtcg attccgcgta atatccgtgg catgattttc tttgtattaa aagaagtcgt
    23881 attttctttc atcgtccact catcttcaga accaccgcga atatagccaa aagctcctgc
    23941 ttccatgcgc tcttttacac gaccttctag ttaggcaatg tttacaatat cgattggatg
    24001 ttcttcatta cttgtatgat aagtcatagt agatccttct ttcatcttct tgattacata
    24061 taaatcatac taaacttaca aaaagtaagc aaacatttac tctcagatac ttttatcgct
    24121 attctttcca aataaatcga cttacaagct gatctacttc ttggttttca tgaagcatac
    24181 tatgagaggc attttcacct gtcactactt tttcctctat ttcatttccg cgttgcttca
    24241 acaacgcata gaccgctaat gcactgttta acggtactgt tccatcactc aagtctgttt
    24301 catctagttg accagcaatc aagaaaaatc gagtggttat aggaatatta ccgatcattt
    24361 gctggtaatc ttgatagcgg ttagaaacga cagcaggccc ctttgctaac tcatctgtca
    24421 gagactgcgc actatcatcg acaaaatcat taaaaggcgc gccaattgct gttaatgtct
    24481 gaacttgtgg caatgacgta tcctgtccat acgttcctaa atagcgtagt gcactaactc
    24541 ctcccatgga atgccccact atgttgactt tatctatgcc gtagttttct ttcagataca
    24601 aaagacaagt tttgatccat tctgcttgat tccactcgtt atttttatta tcttcaaaca
    24661 atacttggac catcggattg tctgcttttc cagacaaatc tcctgttgct tgtatttgtc
    24721 catctgttcc tactgttaaa accaattctt ttactgcttg ctgatttttt tccaaacgcc
    24781 gcaacatccc tttaaaggaa ttttctgtcc cgctgtagcc gtggaaaaaa agtgttggaa
    24841 tagtggtttt ttctatcact ttactggatt ctgccgtttt ttctttatca gaaacttcag
    24901 tagtatttat cttcgtcgtc tggcaaccac ttaacgcaaa caaactgata aggactaaag
    24961 ctgctgcagt tgcacgtttg cataaatttt tgattggttc tgtcatacac ctcttccttt
    25021 ccatatagaa aaaagaaaga cttgaaaggc caatcatatg atcgacattt caagtctctt
    25081 tattaatcga ttttatctac ttgatcgaaa tcaagttctg tactggtttc acgtccaaac
    25141 atatcgatgt tgactttcaa tttttctttt tctccgtcaa cttctgttac ttgtccttct
    25201 aatccagcaa atgcgccttc gatgattttc acgacttcgc caacttctac ttctagatca
    25261 ttttgtcgca ggctcatacc gatagaacgc aagatatgat tgacttcttc tggaagtaat
    25321 ggtgctggtt tgcttccggc tccgtgtgaa ccaacgaatc ctgtcacacc aggtgtgttg
    25381 cggacaacat accatgaagc gtctgtcatg atcatttcaa caagtacgta tcctgggaat
    25441 gttttatgaa cgatttcttt ttctttccca tttttgactt cagtttcttt ttcttcagga
    25501 acaacgacac ggaaaataaa gtcggccatt ttcatacttt gcgcacgaga ttcgatattt
    25561 gcttttactt tgttttcata tcctgaatat gtatgcaaga cataccagtt tttttcaaaa
    25621 gattccattg aaggctcctc atttcattgt aaaataaaaa aacctcagta cacccgaagt
    25681 ttttctttcg cttcattata gcactaaaag tacgttgtgg ctagcgagtt attttaaaat
    25741 ccagccaaat aagctttgga tggctgtatc cattacgtaa aacatcaatc cgaaaataat
    25801 agaagtttcg atgactacta acgtatcttt acggagttgt tttctgcttg gccaagttac
    25861 ttgtttgatt tcatctttta cgctttttag aaatttcatg agacaacctc ccttgctact
    25921 gtttatttcg tttctttatg taatgtatat tgattacaat atttacaaaa cttattgatt
    25981 tccaaacgtt cgccgctttt tccttcactg actgattttg tgtagttgcg agacccacaa
    26041 acggaacaag cgagtgctgc ttttttcttt gccatttact tctgccccct tgctgagaat
    26101 cagacttata cttcataaca gtatcacgta actttttact tgtcaatttg tgaaataaac
    26161 tatctattgt tttggataaa attatgatat gattaatttg aaattaagct aaaatgagac
    26221 aattggaggt atagcgatgc tattaaaaac acttgtatat aagaaaaaag atctgacaac
    26281 cgttacagag actagtacat tagaagaagc attaaaaatt ttagaaactt ccggataccg
    26341 ttgtgtgccg atcttagatt cttcaggtaa tattttccgt ggaaacattt acaaaatgca
    26401 tatctatcgt cataaagcaa atggcggtga tatgacgctt cctgtcactc atcttttgaa
    26461 aaacgctaca aagttcattt acctggatac ttctttcttc aaagtattct ttacgatcaa
    26521 agagcttcct tatattgctg tccttgacag tgaaaatcat ttttatggta ttttgacaca
    26581 tagtacgttg cttaatatgc tctctcaatc ttggagcgta gaacaaggaa gctatgtact
    26641 gacaattgct tccacaggaa agcaaggaga tttggctgct attgcaaaaa tcatttcaaa
    26701 acacagcagc attgccagct gtattactct tgatatcgaa aaagacgaat acattcgacg
    26761 tacattgatc acgctaccgg ctaacactga agcgaaagta tgtgaaacga tcgtcaacca
    26821 cttagagaaa aagaattata aagtggtaga aattgaaaat ttgcaaaacc aagaagcata
    26881 atcaaaaagc gaaaaaagaa aacagctaat ctgctttctt ttttcgcttt ttataattag
    26941 acacgctttt caaaatcaag cgcgcgatct aaataataca tcaatggtgc tgaaacagcc
    27001 atgacgataa actcacttaa tgcaagcgtg ccataggttg tccaaaatgc ttggccacct
    27061 gttggaacta acatataagc aatcagtccc atgctgatgg taaagaagat cgtgttcaat
    27121 actaaacgca tctttacatt tttcactttg ttttgcaata aagctgtcag gcctaaagaa
    27181 agcaatgttt ggccgccacc aaaaaccaca tccatgatac caaaaccaaa gaaggcatta
    27241 tagacgatga ccccgcctaa aactccccaa agcaatttac ggttaaagac aactaaatga
    27301 ttcaaacttt ctgaaatacg aaactggatc ggccctgagg atacaggcgc aactaaaata
    27361 gttaacgcta gataaagagc catgatgatg ccatttacaa cgattacgga taaccgttgt
    27421 ctgcttttcg ttttttgcat tttctctcct cttttctcct agttttttta acgcgggatg
    27481 gttgatgaac cgcggttatg tgaaacaaac aataattata acagactttt catttatttc
    27541 aatccgtctt atctgctttt aaaaaagcaa aagcttaaac aatgtaaacg tttgctaaaa
    27601 atcgtgggat atggtataaa gtaagtgtaa ggggtcataa gaattcccag taaagcagac
    27661 gaagtaggat ctgcaagaac agaattgttg tgaaacttaa ataaataaaa aaggatgtgg
    27721 gaatttgagc aacctcttac tagagaacgg tctagcaagc agctgaagat ctaagtggac
    27781 atgccgaacc ttggaacttc tccttacgta agtaatggat catgcgcttg ctaggctttt
    27841 ttgtgttttt cggtcttcgg acctttttca ttttcctaga cttctgctat aataaccaag
    27901 aattaatttt gtaacagatt tttttgaaaa aacaagtttc tttcattcaa aaaatagaaa
    27961 aagcttgcta attattggtt aaccagcaaa caggagtatt aaaatatctt gttttattga
    28021 atagcaggag gaaatcatga aattccatta tcatatattg atcaatccat cggcaggcag
    28081 cggaaatggc tataaagtag cagaaagaat tttaccggta ttaaaaaata agcatattga
    28141 ctatacactt cattatagtg aatacaaagg acacgatgct gagattgctg aaactttggc
    28201 aaaagaaaca ttgattcctt ggatagaaga agaacagaaa acaatcgata ctttccccct
    28261 tttgatcatc gtaggaggtg acggcacctt acatcaggta cttgatactt tctatcagat
    28321 ggaagtagaa ttcccagttg cttatattcc agcaggttct ggagatgatt ttgctcgagg
    28381 ggcaggcctt ccaaaaaatc ccaaaaaagg acttcagctg attttagcag ctcaatcacc
    28441 agaaaaagtc cacataatgg cttatgaaga aaaaataagt gaaaaaaaag gaatagctgt
    28501 taataatttc ggtataggat tagatgcagc tatcgtccat gcgacaaatc attcttccac
    28561 aaaaaagcga ttgaacaaat acaacttagg atcattttcg tatttattct ctattctccg
    28621 tgctttattc actcaaaaag gatttccaat tctggtagat gcaggaggaa aacaattaag
    28681 tttttcaaac gcatttttat gtacagcaac gaagcatcct ttttttggcg gaggaatcgc
    28741 gattgttcca actgctgatg cgtctaaacc agtcattgat tttgtcgtgg tcgaacgaat
    28801 caatttcttt aaaatcttgt ggctcattct tttacttata cagaaaaaac aattgaaatc
    28861 gaaatatttc catcactaca caacaaacag attacgtatc gtttcaacaa caccgcaaca
    28921 tggtcaagaa gatggagaag aaatggaaaa acgacctttt gatatcacaa taaccacaac
    28981 taaacagttg ttttggtgtt aataaaagag gttttgtcag aagctacatc tggaacaccg
    29041 tttattcgga aaaaaggact gtgacacgac ttttgtcaca gtcctttttt tactatgcag
    29101 ttaattcttt gcccaattgg gttgccatcg atagtttctt tctttaccca aaataaattg
    29161 gatcattgaa aacaccgcag caaaagcaac taagacacaa ccattgaacc aaaaagattc
    29221 tgcaaatgtt tgattgtaac tgagtgtttc actgatcaag ttattatttt gaacaaacca
    29281 atatgttggt gtgaatgccg ctattttgct aaccatttct ggcaagtatt ctgctggtac
    29341 aaacacccca ccgataaagc aactgcctgt gataaaaata tctttgatcc caccgctggt
    29401 ttctgagttt tttaccaatg aagtgataca agccgaaaag ctaatgatcg gcaataaaaa
    29461 caagaaagta tttaaaatat gataccatac cgttatatcc cacgaggtgt ggatcactaa
    29521 cagaaccatt agaagtaaga agccactgaa caacagcagc gagtaactaa tcaaactaaa
    29581 ggttactttg cgattcaagt ttcgtttggt aatgggcgca ctctggtttc gtttactgat
    29641 ctctttgcga ttaaatgcta gattgatgac gctgaaaccg ctaaaaatgg atagaaacaa
    29701 cccataagac aagaaattaa aggttgtgcc cgtcaacagc tttttcatcc gctgactata
    29761 tcccgcactt agctcaactt ctccagtaac cgagagtgcc atttgtgtct gttccatagc
    29821 tgcatcgatt gttttatctt cttcttgaaa cagaatcagt gtttgcaaaa aggtgttcac
    29881 ttgctgtgta acaactgttt tagaaaaggc atctgggcga ctctgtatct tgatcgtcgg
    29941 catctttcct acttcgactt gttcggtaaa gtctgcaggc agatgtaaga taatgtttac
    30001 acgattaaaa taaagagcat catcgatttc tttttgtgag gttccatcca atgtaacgac
    30061 tgtttccttg tcattcaaat atttacgaag gccatcgact acaggcgact cttcttcact
    30121 aatcaaggcg attttcgcat cttgcagaga ggtattttca acatcaatat tttgcgcaaa
    30181 aaagaatgtg gcaacaacag tgataattac acctatcagt aaattcgatt tatttgcttt
    30241 aagcaatgtc caaatcgttt tataaagcgt cataacgcac ccctctttcc atccaagcat
    30301 ttcctaacgc aaaaaggaaa ataaatccga tcaaccatag aagattggta taaaaactag
    30361 ccaaatcagt gtagaaataa agtttataca aactttcgct gatcaagttg acgagattta
    30421 attgaccaac aatcggaata tgaagatcaa tccaatactt cacttgttcc gaccccatca
    30481 taccagcaaa aaagctcatc gcaatcgtca ctgaaatcaa gatgctatcc ttttgcacca
    30541 gattcatttt tggtatcaaa ttaccaacca atgtacctaa caaaatcgca cacaacgacc
    30601 ccagagcggt aacaatcatc aaccattgcc aacgttcacc aaagtctact tgatagataa
    30661 aacgaaagac agctaacata atataaatct ctgtcaaaac aatcgtaaag cttgctgcca
    30721 aattagcgat tgaaactaac gattgctttc taggaatcaa ggacaagcga ataccatttg
    30781 acgattgatt tgcttgctga tcctgtacat tgcggacccc ccacatcgtc ccgtagagaa
    30841 tcgccattcc aatcagagtg aagaaataaa aacttttgaa actcatatta cgacctgcat
    30901 gaacttcttg aaaagatact tcttgttcaa aaacagtcat gatgggcgcg agatcaacgt
    30961 tctccacttc tgccacttta ctcgaaatta taccaatacg ctgtaaaaat tgatccatga
    31021 cgtttttcat caacgtctga ctcattcctg cttgacccac atggagcgaa acagatgaac
    31081 catcaatgag ataaaaacca gccaaatcat ctgcatttag cttttcattc gcttctactt
    31141 ccgatagttc ctgtacttca aataatggtt tatcattgac ttcgacttgt tctaagactg
    31201 tggtaaaatt ttccgaaagc gctgtttgat ccgctttgat tacaattcca gtattaatcg
    31261 tttcgagatt gccaccttga tcaatctcgc caaaggccgc cataaacatc aatcctaaaa
    31321 gaattggaaa ggccaatgtc caaaacaaca tggatttatt tcgcagcagt atttttgtgc
    31381 gatatttata aaaatgccaa aacattattt cccctcctct agtctctcaa atccttgcca
    31441 gtaatctcta aaaagacatc attcaaggac gcttctttgg ttgctatttt tccgtaactg
    31501 atcttttctt cttgtaagat tgtaagaatc ggcaacaata ctgtatttag ttcagtagtt
    31561 gttacttgga gctgaccttt tttataagcg attccatcag aagctattgt tcgctgacaa
    31621 cacgttttct gggagtaatg ggatgtcgat cgtcaaacga tccgccgtcc gtaccatatc
    31681 ttttagagat tctttggttc ctttagcaat cacctgtcct tgatccatga tcacgatctg
    31741 gtcgcaaaga atttctactt cttccatgta atgtgttgta tagacaatgg ttgctccttg
    31801 tcgattcagc tccttgatac tttctaaaat tttattccga ctttgggggt ctacagctac
    31861 tgtcggctca tctaaaaaaa ttaaccgcgg cttgtgggca atcccacatg cgatgttcaa
    31921 ccgacgtttc aagccaccac taagttctcc tggacgaaac gaaacatatt tttctaatcc
    31981 cactaattga atcacctctt caatcaaggc tttccttttc tctttttcgg aaacatataa
    32041 accgcaaaaa taatcgatat tttcttgcac acttagttcg tcaaagaccg caacgtcttg
    32101 aggaacgacc ccaatcattg ccttgacagc ataattttca ggagtcattg ttgtcccgaa
    32161 caatttaatg gttcctttgt cataatttaa caaagaaagc atacagttga tggcagtcga
    32221 tttcccactg ccgtttggtc ctaacagacc taagacttct ccttcttgta cttgcagatc
    32281 aaaatgattc aatgctacaa aatctccata gcgtttgact aatttatcaa tttcgataat
    32341 catcatgaaa aactccttcc aaatttcttg ttgatctgac tataataaag tgcaagaaaa
    32401 gaaactagtg acgattggct aaaccacaca tgacatttgt cacaatgaag gagtctgcta
    32461 tgcataaatc tcggctactc aacgaaacta gctttctact ggttatctca ttgcttttgc
    32521 tggtaagtca aggattcgtt gctatgcaag ttatctattt attgatcgcc gttttattca
    32581 ctggtgtcag ttatttactg cctacaaagc caaattggat tttccaagtt attctatttc
    32641 ttttatgtgc ctttttacct gatcttgtcc tgtttctgcc agcgacgatg cgagtgatcg
    32701 cccctgaaga aagccacctt gattacttgt ttttgttagg ttttttgttg atttcgacgg
    32761 ttggtaatca tccccccatc aaggtcgcct ttgtcgtaat tttgctgttt ttttcctttt
    32821 acttacgaaa aaaagatcaa cgaacgaccg atcttgagaa aaagtacatt gtctccaaag
    32881 atactcattg ggaaaaacaa caagagttat cggaacaaaa taaagcattg gccctgtcac
    32941 aagaaacaca attagccttg caaattgtgg aagaacggaa ccgaattgcc cgagacatcc
    33001 atgacaatgt cggtcatctg ctgtcaagtg cgattttaca aattggtgcg cttgaaatga
    33061 tcaatcaaga accaaaacta aaagaaccat tagaaaattt aagtgccacc gttcacactg
    33121 ggatggatcg gattcgtcaa agtgtccatg acctccatga gacatcgatc tcttttcaac
    33181 actccttaga gtttctgatc gctgattttc cttcttctgt tacgattgaa ggaaacttgt
    33241 ttgaaggatt gaatgaaacg cagcaaaact gcttcttaat ggtcatcaaa gaagccttaa
    33301 ccaacagtat caaacatagt catgccaaaa ccgttgtttt acattttcga acgttgccgg
    33361 ccttttatcg cttgcaaatc acgaatgatg gcaccagccc acaaaaaaat tctgctcccg
    33421 gtattggttt gaaaacgatg cgtcaacgtg ttcaagaaca aaagggacaa gtccatattt
    33481 tccaagaaaa ccagcaattt cagttaacga tcattttacc aagggaggga caccaatgat
    33541 aacagtagtc attattgaga tgatccattt gtgacgaaat cgttacaaac cattttagaa
    33601 agcacgaaag agatccgtgt gttaggcatt ggtcattgtg ccaaggatgc gctagtctta
    33661 tacgaaaccc atcgtcccga tgttttgctg acggacatcc gcatgcctaa acaaacgggc
    33721 atcgatgctg ccaaagaaat tttggctaaa tttcccaaag ccatcctttt gcttttgacg
    33781 acattcaaag atgaagaata catccgcgaa gcattttcca tcggtgtcaa agggtattta
    33841 atcaaacaga acttgcaagc gattattcct tctgtcaaat ccgcttataa tggacaggcc
    33901 gtatttggta atgaaatcat cgagactttc actcaaatga tgaagaataa accgacgatt
    33961 gatagtcatg cttatgcttc ttttagtgaa cgtgagcttg caatcatcaa agaagtagct
    34021 gccgggaaaa acaataaaga aattgcagat gccttgtact tgagtgacgg cactgttcgc
    34081 aattacatca gccaattact agaaaagcta gatttacggg atcgcacgca attggctatc
    34141 tatttttatc agcatttgca ataagtctta tctaacacaa aaaaacctga atgatgctcc
    34201 ttcgcatcat tcaggttttt ttcacatctt ctattcaatt gtcccgcaaa ccatttcctc
    34261 acgattgaaa gaatcaagga ttcgcagggc tgccaggatt cgttggattg ttcggcgtgt
    34321 taggcggaaa aataggcgcc ttgtctaacg ttttttctag ttttgattct tcacgatcgt
    34381 ctcgttctac atcaggactt tcattcaatt tgaattcttt ttccatctca tctaactttt
    34441 taaagtcatt gccagattct tttgctaatt tcgctaattt atcttcggtt tctttagcca
    34501 taaagtaacg cccccctttt gatttcagct tagcatatca cactgaaaaa acaaaagaaa
    34561 acgctaacca acgatcattt ttagctattt ctcatcttta aaatcaagca ttttttgccg
    34621 gtataaaatc gtagggagaa ctgttttcca taccaatcat cggatctact aactggttat
    34681 cgatcacttc tgctgtaaga acgaaatctt tagaaacagc aggttctacc tcttctttct
    34741 tttcttctcc aacaaatgaa gaaaacagat ctggttccac tgtttccatt acttggtttt
    34801 tcgtttcatt cgtcccactg tcatcttcta caggtagctt ttcttttaca acccgtggct
    34861 cttttgtata gttcccatct tcaaatggat catttccgac caaagaatct tcataagctg
    34921 ctagtttggt ccggagagtg atattcattt tatcattatc catgatcctt gatttcaacg
    34981 tagtcatccg gcttgctgat tcattcgcta cacaagtgac ataggcttgc tcttccccta
    35041 acaaaatcaa cagttcctta ctgcgagtca ctgccgtgta gagcaaatta cgctgaagca
    35101 tccgctgata ttgatggacc atgggcaaaa taaccatctt gaattcactg ccttgtgatt
    35161 tatggattga gcaacaataa gaaagagtga ttttattcca ttcgtttctt ttataagtga
    35221 cctcatttgc atcaaactgg ataactaatt catccacttt atcttcagaa tcttttgcca
    35281 agatgatacc cgtgatttct cccatatctc cattgaatac attcaattcg ggagtattga
    35341 ctaattggag gactttgtct cctatccgat aaacggtgtc gttccaatgt acttcctttt
    35401 ttccaggttt ccctggattg aatatctcct gcatcatttt atttaacgca tcgatccctg
    35461 caggtccccg atacattggt gctaatactt ggatatcttg tgcacggaat cccttatttt
    35521 tcgctttttc cacaatttta gagatcaagg gttcaatttg ataagcatca cttcggaaat
    35581 aggaacgatc tttttgattc tttgtgaaat cttttggcag acgtccttct ttgatctcat
    35641 gggcaagagg aataatacta gaaccatcac cttgccgata aatctgattg agttccattt
    35701 tgggaatttg ttcgatttcc aaaagatcat ggagtacttg accaggaccg acagagggaa
    35761 gctgatcttt gtctcctact aagataactt gcatattcgt cggaatcgct ttgaataatg
    35821 tgttagccag ccatgtatcg accatagaca tctcatcaac aatcaaaagt ccgccttcta
    35881 attctttcgt actgactgaa ggtgtttttt cccgtccatt cagccccaga agacgatgga
    35941 tcgtactggc aggcagacct gtcgtttcgt tcattcgttt agctgctcgg ccagttggtg
    36001 ctgcaagtag aataggaaaa atttcttggg tatattttga aggatccaat tccagtccgt
    36061 tcaactctgc aaaaagattg acgattccgt tgatcacagt agttttcccc gtacctggtc
    36121 ctcctgttaa aataaataga ggggaacgga ttgcttcagc gatagcttgt tcttgcgaag
    36181 gtccatactg tatgccgaat attttttcga tacgccgaat attcttctgc acttcttttt
    36241 caggataatg gatttctttt ttacgactga gaaggcgctg gatcgaatta ccgatccccc
    36301 attcagaaaa gtacaaactg ttttcgtaaa gattagtctc ttcttgttgt atctttcctt
    36361 cttcaacaag ttggataatt acagtagcaa cctgatcagg ctggatttca attgggcgac
    36421 ttgtttctaa aatacggatc gtttgctgaa gcaatgtctc cgccggtacg tatgtatctc
    36481 ctgtttgaac tgcatgctga aaaatctgat gcaagatagc tgctcgaatt cttctcggtg
    36541 aatctgctgc aataccgatt tgttcggcta gattatctgc acgtttgaac ccgattcctt
    36601 ctatgtcttc gactagctgg tacggatttt cttcgatgat atccaaagac tcgttcttat
    36661 aggcctggta gatactgaaa gctaactgac taccgaaccc gtaacgattc agtcccatga
    36721 tcacttgatc catcccgtgg tttagccgaa tcgtctcagc aagcatttct ctttttggct
    36781 tcgtcaaacc ggagatttgt tttaataccg aaggatcagc aatgattttt tcgatagcat
    36841 cttctcccag caattctaca attttttctg ctgttttctt cccgattcct gggaattttt
    36901 cgctggaaag atacgctacg atcccatttg cagttgttgg cttttcttgc tcatatcttt
    36961 cgagtttaag ctgccttccg tatttaggat gatccactaa ttctccataa aaacgataag
    37021 tctcattttc ttgaatatcg ccgaaacttc cggtgactac aatctctttt tcacggtaat
    37081 cagctgtggt ttcactgatg tgtaccaaaa gcactttgta aaaattacta ggattttgaa
    37141 aaaaaatcgc ggcaactgta ccaacgaaat aaggcatttc ttctggctgc atcggaagcc
    37201 gcctccttct tctatagtaa aggttctggt gctgtttcag ttcctaaaaa atctgtttgg
    37261 ttccatactt tcagttcata tggcaataat ctgcaaggct cttcagtctc taaaatcgtc
    37321 aaactactat tgaacaatcc acccatttca cgcaactcac ttagctcttt tcctgtcatc
    37381 cattgaatgg ctgcagttaa agaagctcca tgtcctacga ataaaagtgg gccatcttta
    37441 tgttgggcaa ccgcatctgc tacaacagtt tcgatacgtg tgattgccga ttcaatcgtt
    37501 tctccgtgaa aaggagaagg atcatacaga tctaaatgat tacgcaaatt cggcagatta
    37561 tccggatatt tctggtacat ttcatcgatc gactgacctt ctaaagtacc cagccctagt
    37621 tctcttagct tatctgtata aaaaatctct accggacgag caagctcttt gttgatacct
    37681 tctgctgtat cacgtgctcg ctttgctgta ctggaataaa ttgctttaaa aggaacatat
    37741 tttacctttt tcccaaatgc tttgatttct tcgtaacttt gtggcaaaag cggagaatcg
    37801 ccattgctcc cttgaaaacg tctttcctga ttccattgtg tcttcccatg tcgggtaaaa
    37861 tatagttcca tacgcagcaa actcctgtct ttcttttatt ttactctata ataaactgtc
    37921 taatccagct tgtcattttc atagtgatgc gtcaattcta aattagggaa tccttgctgg
    37981 cgaagtgctt catacactat cattgcagct gtattcgata aattcaatga gcggacatgc
    38041 tcatcattca tagggatgcg taaacacttt tcttcgtttt cacgcataaa tgtttctggc
    38101 aaaccggttg tttcttttcc aaataaaaag aagtgctctt ctccatcagc aaaattttcg
    38161 tcactatata ctttatgggc aaattttgag atcaaatgta gtttacgatt acctaaaaat
    38221 gttaaaaaag cttctaaatt actgtggtaa gtaatattta catcattcca ataatccaac
    38281 cctgcccgtt ttagatgttt gtcatcagtt gaaaaaccta gtggctcgat taaatgaagc
    38341 ggagtattcg tggctgcaca cgtacgggca atatttccag tgtttgcagg gattaatggt
    38401 tcaaataaaa cgatatgatt catcaggatc attcctctca tatttatgtt cgtttctatt
    38461 ttctgacaat ttgatttttg cataaaaaaa aacgtatcaa ctcggtgtca gtcactgcga
    38521 gtcgttacgt tagtgaagct cttctcacta acttttatca gaacaggaac ctgataaaaa
    38581 ccaatgaaaa aacaacttgt tgctaatata acaccctcaa cttttttttg caacctctac
    38641 tcattaaaaa ctgctagaaa aacgttttct cttagttcct tttaataatt ctatgtcaat
    38701 tgtaatcttc ttcaaaggat tcttatataa gtctgctttg attcgctctt ctacctgcca
    38761 ttctaaaggt gacatggcca aaagatcttt ttgattttcc tctggtatct caaattcata
    38821 ggttacacgc tgacgttcag ttaatttcat tgcttcagca aacttggcta ctacacgttc
    38881 attggaataa ctctgttttt caggttgatt cggataaaaa gcctgacgta gttcctttaa
    38941 ataattttct tgtggcacca ccttcaacac ttctccatct tctgagagta cacgttggaa
    39001 ttcttggtaa tgagaaggcg aaaagatatt taaaaccgcg ttgaatgttt gatcagcaaa
    39061 cggcaaattg gtcaaatcag ctacacacca aaatgcttcg gcagattgtt ctgtagctgc
    39121 gtagactcct tcttttgaaa tatcaaatcc aacagcattt tgaatctttt tcaattttga
    39181 aagttcattc aagaagctac cttctccgca gccaacatct aatagcgaga cttcttcagg
    39241 taaatgctgc gcaatagtct caataacggg ctgatacatg ccagattgga tcattctacg
    39301 ccttggaacg aacattcctt gatcgtattc tgttttaacc gcatgggata aaaaataaag
    39361 tgttcctttt ttggaaaggt caaaacggtg attatttttg catatcaagc cattatcaga
    39421 cttttttact tcttcttggc aaaccggaca gcggaacagc tgatgatttt ctgccaaaaa
    39481 ctggcgtcct cggtcaattt tttttaacat agttccccct catttctgtt ttatcttacc
    39541 gttagatgct cactttggca actgctaaaa atatgataca atgcctagaa gaaagtgaaa
    39601 gataaaggag aagattagat gatcaaagaa ttttgcgctg aaaactacac atctattcct
    39661 ctagcaattg ctagaggagc cgatcggatc gaattgtgtg acaacttagc ggtcggtggc
    39721 acaaccccga gtactggtgt gatcgaagaa acgttaagtt atgctgggga aaaagatatc
    39781 cccgtaatga cgattattcg tcctagaggg ggcgacttcg tctataacga tatcgaattg
    39841 aaaatcatgc atactgattt gattgaagca aagaaattag ggacggatgg cgtagtattt
    39901 ggttgtctta ctccttcagg ctggctagac gaagaggcct tagaactatt gatcgaaaca
    39961 gcagaagggt tgcagatcac cttccatatg gcttttgaca gtattcctga agatcggcaa
    40021 ttcgaagcaa tcgattggct ggtagaacat ggtgttgacc gtatcttgac tcatggcggt
    40081 cctgctgaca aaactattgt agaaaatttc ccacggctta aagaattgat tgcctataca
    40141 gatggccgct taatcatttt gcctggtggt ggtgtcactg cagagaatgc agcacatgta
    40201 gctaaagaat tgaacgtaag cgaagtacac ggaaccaaaa tcgtggatct tcagttataa
    40261 tcttataaac aaaaaaacat ttgcaacagg cataatgctt attgcaaatg tttttgtttt
    40321 tttacataaa atagcccata aataaagaag caatattgaa ataaatcagt acactcgtca
    40381 aatcgctcaa agtcgtgata aagggaccgc ttgctactgc tggatcaaat cctagacgat
    40441 ccattagcat cgggattaaa ctacctgcaa gattcgccac tgtgattgca aatagcatag
    40501 ccatccctat gacaaacccc aagataaaat tatgtttcca aaaacctacg attagaaaaa
    40561 tcgtgatccc cgtaacagct cctgtgacaa cgccggtcaa gacttcagcc aaaacaagtc
    40621 gaacaaatcc atgatctttc tcatcagaaa tcgcaagtcg acgaacagcc acagctagcg
    40681 actgggttcc agcattaccg gcagttcctg taatcagcga aatgaagact gctaaaatac
    40741 tcgcttcact taccaagtct tcatagtgac tgattaaaga agcggtcgac atacctaaaa
    40801 acaacagagt gatcagccaa ggcaaacgtc gagacgctgc ctttactgga ttttcattaa
    40861 tttcttccac attgaccccg gcaagtcctg aataatcgct agcagcttca tcatcaataa
    40921 cgtcgatgat atcatcgact gtgacgattc ctaacaaatg atcatcataa tcggtaacag
    40981 gaagagctaa gaagtcataa tctctaaatg tttgtgccac atcttcttgg tcgtcgccta
    41041 catgaactga aagcactcgt tcgctcatca gatcagaaat cattgcgtcg tcatcattca
    41101 cgattaggtc gcgcagagaa ataaccccta ctagctgacc ttcttgatta acgacataga
    41161 tgtaatagat tgtttcagct acatctgctt cgttcttcag cacgtacatc gcagagcgaa
    41221 cagtttgatt ggctacgatc gaaacaaatt cagttgtcat gatcgcgcca gccgtttcat
    41281 cctcgtaatg gagaagttcc ttgatttcac tggcatcgtc tgccgacatc aaacttaaat
    41341 atttagcaat ttgcttttta tccagcgtat taagcaagtc aacagcatta tctgtataca
    41401 tctcagaaag catatcagct gcatagctag gacgcatttc atctaggtat tctttcatat
    41461 gttcgttgtc ttcttcaatc acatcgaaca tatccgctaa ttctttaggc gacagatagg
    41521 aatagatcag ctgcctgttc tcttctgtaa gagattggta gaattgcccc tgctcataga
    41581 tatgcatctc taaaaaactg tttctgaatg cctgaatatt attttccctt aaatcttgag
    41641 tcaactgggc aaatctttcc tctaattctt gattttcatc caaaccaatc tcacctcgcc
    41701 ttattcttca aaccgtctca caactgcctc catgtctgcg gctaaaggct gcttgaactc
    41761 cagcaactct tctgtaaatg gatggtaaaa acgcagatca taacaatgaa gggcttgtct
    41821 ttttattccc agatccattc gcccgccata catatcatca ccgagcaggg cacagccaat
    41881 tgcggaaaaa tgaactctta tttgatgtgt ccttcctgta tgcagctgga tatcaactaa
    41941 cgcgatttct gttagtcgct tctctatcca gtactcagtc tgtgccgaac gtccttcatc
    42001 agagaccatt cgcttcaata gcgaagaata atctcgggcg atcggcaaat cgatatgtcc
    42061 atgtgccgat aaatctgaaa gccttccact gactaaggcc tgatattttt tcacaaactt
    42121 cttttcacga agttgcatat ctaattttgc gtgcgcaaat ccatgctttg caaaaagcat
    42181 caaaccagat gtatcccgat ctagtcgcgt caccacatgg attacttggt tttcgtaacc
    42241 ttgtttttta taataagcct ttacacgatt agccattgtc ccatttggat ggtattgggc
    42301 aggaatagac gaaacgcctg ctggtttatt tactaccaga acgtgttcat cttcatacac
    42361 gatatcgatc ggtgtttcat ccaaaagtac ggtttcatgt tctccttcag caggaatcac
    42421 aatggttacc ttatcatcct tagctagaga aaacaagaca ttttctactt gatcattaac
    42481 tttgatttga ccgccttgaa attttatttt cgctaacaga ccctttgaga tccctttttc
    42541 ttttaaaaaa tattttactt gctgagaatg atctttctca taatcccatg taaactgcat
    42601 atcaatcctc actaataaag gcatctttca cacgatgcca aaaatgcata tgtcgataag
    42661 aagcaaaatg gatccgttct tctgctattc gataataaat tgagcggata tttgcttttg
    42721 cgacattcaa ttgatcaacc gttacaagat aatcttctgt attttccaat tttatttcta
    42781 gccattcatc atgggcaatc acgatcggag aacccaaagt acgaaacact cgattattca
    42841 gtgaagcaat ctctgccaac tgaaaggcat tgatactagg atggatcaca gcaccgccga
    42901 cacttttatt atatgctgtc gaaccagtag gcgtagaaat cgtcaatcca tctcctctaa
    42961 aactttcaaa cagctcgttt ttgatgtata catcggctac catcgtacga ttggcccgtt
    43021 taatcgttga ttcattcagt gctaaaaaat gctggtccgg tgtttcatcc aaataactga
    43081 tccgaacatc cagcaaggga taactaacac tttgttcccg gttcgttcgt aagctgtcta
    43141 ctagttcttc cagctcgtaa tcccgccaat ccgtgtaaaa ccctaaatga cctgtatgca
    43201 cgcccaagaa acgcacatca ttcagacaat gactgtagtg atggaacgcc gacaataatg
    43261 tgccgtctcc gccgactgag atgaccaatt ctggctcatg atcatctcgt tgaatccctg
    43321 cttgttctaa aagtgcgttc aaacgttctg tcacttctat agtctttgct tctttattat
    43381 gaacgatcgc tactttcatc ccctgcctcc tctctttcgc tttctttctt caaaagcgtt
    43441 cgatagtaga catcatctga ttttcctctt ccatgggaga ataaccgctg tgcttcttgg
    43501 atttcttcac ggatactgga catctcttca tccaactgat aggcagcttc tgccgcacgc
    43561 tgaagtcgtt cactcatttc ttctggaaaa acgccttgat atttataatt cagcgaatgc
    43621 tcaatcgttg cccagaaatt catcgcaaga gtccgaatct ggatttccgc caaaattttc
    43681 ttctcaccgc tgatcagctg tacaggatac tcgatcacca gatgataaga acggtagcca
    43741 cttgcttttt tatttgtgat gtaatctcgt tcttggagaa ctttcatgtc ttttctttta
    43801 cggatgatct caacaacttg atggatatct tctacaaact gacacatgat ccttaacccg
    43861 gcaatatcag acatttcttc ttctaaacgt cccattggaa tatgccgtaa ttgtgatttt
    43921 gttacaatac tatcgactgg cttgactctc ccagtgacaa attcaatcgg gacatgtcga
    43981 ttttgttcac ggaactgttt gcggatcccc cgcagtttca ctttcaattc tgatacagtt
    44041 tgttcatatg gtgctaaaaa tgcttcccaa tctcgttcca tagctgatac ctctacttca
    44101 ttaacattca ttgtttattc taccatatat gcaaagtttt ttcgtactct tgatttatgc
    44161 attgaccaaa aaaagaaaat taggcaaaat agacaaaaag gagtcgatca aatgacacaa
    44221 atgcttgaaa tcgaatataa atctatgctg acaaagcaag agtacgagat attcatcgct
    44281 cactatcaat taacagataa agatttccgt gtacagacta atatttattt cgataccgtt
    44341 gatgaacagc tgaagaaaca aaattgtggc ctacggatcc gtttcgttgg tcatcaagct
    44401 gaatatacat taaaaacacc tgctgaaaaa gggcgtctcg aaacaacgga tacctttata
    44461 acagaagaag cagaagcatt tatcttcgaa aaacgtctgc ctcgttcagg cgcagttttt
    44521 caaaaacttt ctgatttgaa tatcgatcct gcttcattaa tccaaaccgg aaagcttaca
    44581 acaaaacggg ctgaattccc tattgaagaa ggacttttag ctattgatga aagctgggga
    44641 gacaatctac acgattttga actggaacta gaggtagggg atgcatctgt gggaaaaatt
    44701 gcttttataa attttttaaa acgtttttct ttaccttatc gtcctgctaa gaacaagatc
    44761 caacgtatgc ttgaagctaa aaattagaaa cctttcattt tcacaaggca cttgagttca
    44821 tttttttact tttttctgtt aagttatagg atgtgaaaga atctagtcac tagttgtata
    44881 gaatctattt tgggggagat tcatatgatc gaaatctatt tatttgttaa tcctttaggg
    44941 gaatactgtt tcgaaatgga acaacagtta ttacaattta tcgaagaaga gtacgggaca
    45001 ccatcaaaag aaaagatgca atttcgcttt cttcctttgg tcaatttgca gacaattggg
    45061 gatgtcatgc aacaaaaagg aatttctcag aacaatcttg aggaacgtaa tcacttattc
    45121 tcaatgactt attctgcagc attggactgc aaagcggcgc agtttcaagg aaagaaaaaa
    45181 ggccgccgtt ttttgatcaa attgcaagaa gcagtcggct gtaatgacat accatattct
    45241 caagaacttg ctgaatccat atttgaagaa atcggcggcg atttgaatat gtttaaagaa
    45301 gatcgtcagt ctgacttcgt taaagaagta ttcttttctg atcaaaaaat tgctcgggaa
    45361 atgggcatca caaaacaccc ttctgcagtc gtttacaatt atgcctgcga ccgtgatttt
    45421 ggtgttttag tagaagtaaa aggtacaagt agcctttgga gaatcacaga gctgtgtaaa
    45481 acaacagata actcatatca agtttttaat ggtgaacatt tacatacaaa tgattctcag
    45541 ttccattcaa gaactagcca tttacacttg ctttctaatt aaaaaaatac gtcgactccc
    45601 ttacaagaga gccgacgtat ttttttcgtt tctattcgag aaaatcaaaa atagaaagcc
    45661 ttataaacga tcgatcaatt cttctaattc atttagacgt tgttcaaaca tcgacattgc
    45721 atcttcaata tatgcagcct gtgtcatatc aactcctgct tttttcatta cttccacagg
    45781 ataatcgctg ttacctgctt ttaggtaagc caagtagttc tctagtgcct ctggttcctg
    45841 gtttagtatt ttcttcgcca gtgctgaagc agcagaaaag ccagtcgagt attggaaaac
    45901 atagtaatta taataaaaat gcggtatccg tgaccattcg aatttaattt ctgggtcttc
    45961 ttcgactgct ggaccataat attttgcatt caatttacca taactatcac ttaggtattc
    46021 actagtcaat ggcacacctt tttcatcttc cgtatgcatg aaatgctcga attcagcgaa
    46081 ttgtgtctgg cggaaaactg ttcctttaaa cccatccaag taatggttga gtacataagc
    46141 ccgtacacga gggtcttttt ctgtttccaa taaatactcc gttaggatat tttcattcgt
    46201 tgtcgaagca atttctgcta aaaagatgga gtagtcgccg tacacataag gctggttcga
    46261 acgagtgaaa taactatgaa cactatgtcc catttcgtgg acaagcgtaa atagctgatc
    46321 cagcgtatca tgccaattca ataaaatata tggatttgtg tcatagcttc ccgaagaata
    46381 agcatcgctt cgtttccctt tattttcgac aacatcgatc caacgttcag agaatgcttt
    46441 ttctacgatg gccatgtatt cttcacccat tggtttcagt gcttctaaag ctttttcttt
    46501 tgcttcttcg tacgtaaagg taattggagc ttcccctaag accggtgtat aaagatcata
    46561 catgtgcagt ttttccactt ctaataaacg tttccgtaat tccatgtatc gatgtaacaa
    46621 aggcaaatgc ttgtttacca cgtctaccaa agtatcgtat acactttcag gaatatgatt
    46681 attgctcaaa gacgcttctc tggcagagct gtaattacgg actttcgctt taaaattatg
    46741 tccttttata tgtgtgccta aagtagaagc aaatgtattt ctaaattgtt cgtaaacact
    46801 gtacaatccc ttaaatgctg cttcgcgcac ccttcgatcc gtgctttcta gcaactgacc
    46861 atacacgcca tgagataatt ggactatttc accattttct ccttcaatcg ttggaaaaac
    46921 tagatctgca ttattcaaaa cagcaaatgt atcacttgaa gcatcaaaga tttcacctgc
    46981 tccagcaaga agagattcct gctcagcaga taagacatgg gctcgattat ctactatttg
    47041 ctggatataa tggcgataga cttccaattt tggttcttct ttgaaatatt gccaaatctg
    47101 gtcatctgac aattgcaata tttctggttc aaaccaggaa acggcttcac taactttcga
    47161 aaacagactg cttgctcttg cataaagcgc ttggtaatct gtatttccag tgtcttgatc
    47221 gtttttaagg tgcgcatata cataaatgac ttcagtttgg cgataaaccc tcaatacgaa
    47281 ttcaatcgca tttaaaaatt gagaagcgcc ttgatcaagt gttcctttgt gtttttcaga
    47341 ttgttttaac tcttctgata attccaaata tttctcatca aactcttggt cgcttgaaaa
    47401 gatcttggtc aagtcccaag ttaaattttc aggcaattct tctcgttttg gcaactgctt
    47461 tacttccatg aaatccactc cttttcttcc cttagctcta tctatcaaaa tagatcatag
    47521 tctaacatcc acatgtcaca gcatctaact tttctactca ttcatgtgtc tgcttccatc
    47581 aattttagca taactaaatc ttgttttaca tagaaaaccg attcctagcc tatttttata
    47641 cttactattt tttcaaagaa gacaagtgta tgcattcgtt aaaaaactgc tgatagacca
    47701 tctcttcatc aatcatagga aaaagccatt cccttttatg ttcttttatt tggcaaagcc
    47761 atgagttgaa atcaggaact ttctggtttt ccaaggcttc ttcgtacaac attcgataaa
    47821 gaaaaacctg ttcttgtaaa taaaagaaaa accgactttt ttgatagatc cacgatgata
    47881 gatgcaaaag atgtttatga cgcaagtagc attgttcttg tatggatact gtattctttt
    47941 gcttgtgaat aagttggcgt gtcagccatt tcttcccatc ttcactcact ttttctattt
    48001 ttttcatttg gttcatttta atttcgttac tagtgaatat ttctttaagg tccctactag
    48061 aaaaagtcca gcagctactg caaaaggaaa tatgccctga tacagtctct gtaatatgat
    48121 gatacaaata aagcttttgt ttcttgagat cagctttcca gcaatgcact cctctttttc
    48181 tattatagta gcagcaactt ttttctatca atgagaattg cgattgtcca agaaaagaat
    48241 taccaagtat ccaccatact tggtaactgt tattcaaata attttgggtt ctttcaataa
    48301 atctctggtg agacagtcta gaacattgga tttctattgc tagattcgcc aacaaaatat
    48361 ccggcctttg ccgcaacctc ggcaaatagg cttccaaaaa tactggttct actgactgtc
    48421 ccagccaatc catgaagcat tcctttaact gtaagtgctc ttttgattct ctttcactaa
    48481 agaccgaaca gttatctgat ttttgatggg caaaatgagc acattttttc tttccctttt
    48541 tcaaaatcac tctttttcga cagccacgac aataatattt ctttcctttt tctgcatgtt
    48601 tagcaaaaca gcacttatta tattcattca ttgcaagcag catttttctc cctctgaact
    48661 tatttacgtc taagaattta tttacacgaa aaaagagggc gtgaaaaagc tattctgcat
    48721 caagtaataa gaacagctaa acaaaaatag ttcccaatat ttttcgtttg gttgggcttg
    48781 ttaccgcaga tgcaagcttt tgaacacatt tatacgaaaa aaagactgcg acacaatttt
    48841 tgtcacagtc tcttactata atgctgattt atacaaaata aaatttcgtt cgctcgatag
    48901 cattacgcgc catcagacat tgtccatatt cattcaatgt ttctggtgta cgatcgctct
    48961 tttcagcaaa ctccaaaatt cgagcaatct gattctctac atccgcttgg ttgagatttt
    49021 ccatccagaa gtgaacgact aggtaatagc gctcttcgaa taaatacaaa tcagtccaag
    49081 cagactctag ttcgacatct gttgcaagtt ggatcacttg ttcaaaatct tcaaaagcaa
    49141 aagttgcttg tctttcctgt tcttctaggg cgcttccaga taattcttcc tccggatcgc
    49201 tgccaataat ctgctgacga agaaagtcac tcacatcttc tgaatcaaca gtagaatctt
    49261 ctgattgaga aatttcttca tccggaagat ttttactgat aaacagttct aatccgtctc
    49321 cttttggcaa aacttggaaa gtgacagctt cgcttcctcg gaactcctct tcgatatcaa
    49381 cttcttccaa aatactataa aagaaatttt cgatttcttt gtgattgcca agtaaatcca
    49441 aaaatgaaac gccccgttcc tctaaatctt catgaccaat tagtacacgg atcgtatttt
    49501 cattaatatg ttccatttcc attttgctac acctcacttt gccacaatgt ttaatataga
    49561 ttcattgtag cgaaatcagc ttaaatgtaa agaaaaaaaa tctcgctgtt aagcgaattt
    49621 aataaaacca gcggattttt caacctttca agctatctta tttaactata acatttttgg
    49681 cagacgaata ctatatagcc gacttttcag ctaattttcc ctctctattt ttcgtgcaat
    49741 catcatcttc tactaccttt ttatacatct aatcaagaat actttttgta aaaacaaaaa
    49801 aacttggaaa aactatcttt gtaatagtct tt
//
LOCUS       DAZKNV010000016        47470 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000016 DAZKNV010000000
VERSION     DAZKNV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.016"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(55..789)
                     /locus_tag="ACG8M1_001009"
     CDS             complement(55..789)
                     /locus_tag="ACG8M1_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFQ0421736.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1116..1526
                     /locus_tag="ACG8M1_001010"
     CDS             1116..1526
                     /locus_tag="ACG8M1_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFQ0421737.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1519..2220
                     /locus_tag="ACG8M1_001011"
     CDS             1519..2220
                     /locus_tag="ACG8M1_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFQ0421738.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2220..3806
                     /locus_tag="ACG8M1_001012"
     CDS             2220..3806
                     /locus_tag="ACG8M1_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421739.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3825..4046
                     /locus_tag="ACG8M1_001013"
     CDS             3825..4046
                     /locus_tag="ACG8M1_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFQ0421740.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4043..4804
                     /locus_tag="ACG8M1_001014"
     CDS             4043..4804
                     /locus_tag="ACG8M1_001014"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFQ0421741.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5184..5693
                     /locus_tag="ACG8M1_001015"
     CDS             5184..5693
                     /locus_tag="ACG8M1_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFQ0421742.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5768..6307)
                     /locus_tag="ACG8M1_001016"
     CDS             complement(5768..6307)
                     /locus_tag="ACG8M1_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFQ0421743.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACG8M1_001017"
     CDS             complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACG8M1_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFQ0421744.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7320..8171
                     /locus_tag="ACG8M1_001018"
     CDS             7320..8171
                     /locus_tag="ACG8M1_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFQ0421745.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8199..8834
                     /locus_tag="ACG8M1_001019"
     CDS             8199..8834
                     /locus_tag="ACG8M1_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFQ0421746.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8854..9627
                     /locus_tag="ACG8M1_001020"
     CDS             8854..9627
                     /locus_tag="ACG8M1_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0421747.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10035..10832
                     /locus_tag="ACG8M1_001021"
     CDS             10035..10832
                     /locus_tag="ACG8M1_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFQ0421748.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10810..11223
                     /locus_tag="ACG8M1_001022"
     CDS             10810..11223
                     /locus_tag="ACG8M1_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0421749.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11207..13852
                     /gene="mutS"
                     /locus_tag="ACG8M1_001023"
     CDS             11207..13852
                     /gene="mutS"
                     /locus_tag="ACG8M1_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFQ0421750.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13870..15978
                     /gene="mutL"
                     /locus_tag="ACG8M1_001024"
     CDS             13870..15978
                     /gene="mutL"
                     /locus_tag="ACG8M1_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFQ0421751.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16000..16560
                     /locus_tag="ACG8M1_001025"
     CDS             16000..16560
                     /locus_tag="ACG8M1_001025"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFQ0421752.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACG8M1_001026"
     CDS             complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACG8M1_001026"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFQ0421753.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18856..19569
                     /gene="treR"
                     /locus_tag="ACG8M1_001027"
     CDS             18856..19569
                     /gene="treR"
                     /locus_tag="ACG8M1_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFQ0421754.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19646..20092
                     /gene="msrB"
                     /locus_tag="ACG8M1_001028"
     CDS             19646..20092
                     /gene="msrB"
                     /locus_tag="ACG8M1_001028"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFQ0421755.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="ACG8M1_001029"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="ACG8M1_001029"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFQ0421756.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="ACG8M1_001030"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="ACG8M1_001030"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFQ0421757.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="ACG8M1_001031"
     CDS             21907..22485
                     /locus_tag="ACG8M1_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0421758.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="ACG8M1_001032"
     CDS             22537..23019
                     /locus_tag="ACG8M1_001032"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFQ0421759.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="ACG8M1_001033"
     CDS             23136..23510
                     /locus_tag="ACG8M1_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421760.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACG8M1_001034"
     CDS             complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACG8M1_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFQ0421761.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25687..26277
                     /locus_tag="ACG8M1_001035"
     CDS             25687..26277
                     /locus_tag="ACG8M1_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFQ0421762.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26405..27754)
                     /locus_tag="ACG8M1_001036"
     CDS             complement(26405..27754)
                     /locus_tag="ACG8M1_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0421763.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27922..28662)
                     /locus_tag="ACG8M1_001037"
     CDS             complement(27922..28662)
                     /locus_tag="ACG8M1_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421764.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28675..30267)
                     /locus_tag="ACG8M1_001038"
     CDS             complement(28675..30267)
                     /locus_tag="ACG8M1_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0421765.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     regulatory      complement(30405..30579)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(30835..31131)
                     /locus_tag="ACG8M1_001039"
     CDS             complement(30835..31131)
                     /locus_tag="ACG8M1_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421766.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31307..32032
                     /locus_tag="ACG8M1_001040"
     CDS             31307..32032
                     /locus_tag="ACG8M1_001040"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFQ0421767.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32025..32867
                     /locus_tag="ACG8M1_001041"
     CDS             32025..32867
                     /locus_tag="ACG8M1_001041"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFQ0421768.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32870..33391
                     /locus_tag="ACG8M1_001042"
     CDS             32870..33391
                     /locus_tag="ACG8M1_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFQ0421769.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACG8M1_001043"
     CDS             complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACG8M1_001043"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFQ0421770.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34458..34727
                     /gene="rpsO"
                     /locus_tag="ACG8M1_001044"
     CDS             34458..34727
                     /gene="rpsO"
                     /locus_tag="ACG8M1_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFQ0421771.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34915..37041
                     /gene="pnp"
                     /locus_tag="ACG8M1_001045"
     CDS             34915..37041
                     /gene="pnp"
                     /locus_tag="ACG8M1_001045"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFQ0421772.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37551..37817
                     /locus_tag="ACG8M1_001046"
     CDS             37551..37817
                     /locus_tag="ACG8M1_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0421773.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37961..39952
                     /locus_tag="ACG8M1_001047"
     CDS             37961..39952
                     /locus_tag="ACG8M1_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFQ0421774.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40306..41607
                     /locus_tag="ACG8M1_001048"
     CDS             40306..41607
                     /locus_tag="ACG8M1_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFQ0421775.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41737..43107)
                     /locus_tag="ACG8M1_001049"
     CDS             complement(41737..43107)
                     /locus_tag="ACG8M1_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFQ0421776.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43289..43612)
                     /locus_tag="ACG8M1_001050"
     CDS             complement(43289..43612)
                     /locus_tag="ACG8M1_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFQ0421777.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43937..44545)
                     /locus_tag="ACG8M1_001051"
     CDS             complement(43937..44545)
                     /locus_tag="ACG8M1_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFQ0421778.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44875..45591
                     /locus_tag="ACG8M1_001052"
     CDS             44875..45591
                     /locus_tag="ACG8M1_001052"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFQ0421779.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45604..46299
                     /locus_tag="ACG8M1_001053"
     CDS             45604..46299
                     /locus_tag="ACG8M1_001053"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFQ0421780.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46383..47012
                     /gene="udk"
                     /locus_tag="ACG8M1_001054"
     CDS             46383..47012
                     /gene="udk"
                     /locus_tag="ACG8M1_001054"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFQ0421781.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8788 c         9878 g        13413 t
ORIGIN      
        1 ataaaaaaac ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc
       61 cataaataat aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac
      121 tggtacccat gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg
      181 tacaagacgt ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag
      241 tgaagcaact aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc
      301 ttggaagaat ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa
      361 gaattcattg acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc
      421 taacacatgg tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat
      481 caattgtcca atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca
      541 agggaataga ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct
      601 gattccacca aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag
      661 catccagtca ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt
      721 acctagaacg attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga
      781 gtaatccata aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg
      841 aaaagcatcg gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat
      901 aaaaaaatga attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt
      961 taaaagttct ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt
     1021 tttctcaaaa attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta
     1081 gtaaaatgaa agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca
     1141 ttattatttt cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc
     1201 ctggaagtat cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc
     1261 ctgaaaaaat cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc
     1321 ctgctggtgt aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac
     1381 tgggagcagt cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag
     1441 gtgtagaagc tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg
     1501 aaatggagga gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg
     1561 actttaggag tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg
     1621 aatcctctcg tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc
     1681 tataaagact ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg
     1741 gcacttgcca tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta
     1801 atggctgcga ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac
     1861 ttcttctctc ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct
     1921 atttctgtcg atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt
     1981 gtctctacag gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc
     2041 gaaagtccag ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca
     2101 aaagcaatcg agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac
     2161 ggaatattga ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga
     2221 tgcgaaaacc actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga
     2281 aagacgtgta tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga
     2341 ttctcctcct agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag
     2401 ttgttcagct ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc
     2461 agcagtttag cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact
     2521 tttatgatac gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta
     2581 cgctgaaatt ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat
     2641 ttgcgcaaaa gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac
     2701 agcaactgca aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag
     2761 aagaaatcat tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct
     2821 ggccatttga aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt
     2881 tttttaatgt tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct
     2941 tttttttaag aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga
     3001 tttctgacaa tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt
     3061 attttcaagt agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat
     3121 attatagtga tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac
     3181 cgccctttac agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg
     3241 ggctgccagc agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt
     3301 tcgcctatct ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta
     3361 atcatttagt tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta
     3421 gacacaaaca tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc
     3481 tgactgtgtt taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt
     3541 taatgacaga tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt
     3601 tccgtaatga gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc
     3661 ttctgatttc gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg
     3721 tgactgaaga actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc
     3781 aaaaacaaaa actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa
     3841 ttttaccaga attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac
     3901 tttatgttgt tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat
     3961 tgatcaaaac aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag
     4021 cagatgattg ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt
     4081 atttatcaca ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca
     4141 agatgctttt gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg
     4201 atttcctgaa acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca
     4261 agcggtatcg aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg
     4321 gatattggat gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta
     4381 tgagacgaat gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg
     4441 ccaaaaaagc ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg
     4501 tgggatcgct tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct
     4561 ggattacgca ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc
     4621 aatgaatgcg gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac
     4681 accagtcaag cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc
     4741 tcctcaagca agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa
     4801 ataaccttgt gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg
     4861 atgataaaaa aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa
     4921 ttctttttaa taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa
     4981 acgatattca aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag
     5041 ctatttttat ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc
     5101 gacacttcag ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt
     5161 atcttgcaaa ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga
     5221 caacgacaga tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg
     5281 ttttgtctgt ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc
     5341 tgtccttgta taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata
     5401 ttgcttctcc tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat
     5461 tgcttatcaa ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga
     5521 cagcatgcgt atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc
     5581 aactaccttt tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg
     5641 tcggtgggat aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg
     5701 tttaatttaa aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct
     5761 tttttgatta atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat
     5821 aagctgctcc agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa
     5881 atgcagttgt aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg
     5941 cagcaagaga gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt
     6001 cgatcatcca accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg
     6061 gcccaaataa aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc
     6121 caagtaaaag ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg
     6181 ttaatccaat agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct
     6241 gagaaaggac agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc
     6301 ggttcataac gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa
     6361 acaaagtgat tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc
     6421 ggtctttttc aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga
     6481 gcttcgtcga tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc
     6541 aatttttcag cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct
     6601 tttactgtta cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg
     6661 tggtatgaag ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat
     6721 tgacgtgctt gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt
     6781 tgttctagta agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt
     6841 acgaacaagt tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt
     6901 tcagttaatt gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct
     6961 ggtgcgtaag ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga
     7021 cgagaaattt tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat
     7081 aagtttttgg agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat
     7141 cttcaccttt gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat
     7201 gagttattat ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca
     7261 cgaatgtcaa gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa
     7321 tgagagggta tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc
     7381 cggtatcacc attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg
     7441 aaaacagctt ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag
     7501 gaacggctgt ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa
     7561 agattttata cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg
     7621 aattaggaac atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt
     7681 taagtaaggc agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat
     7741 tatgtggatt tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta
     7801 tgttagaatc aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga
     7861 tgtttgcgaa tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg
     7921 tcggaaaagt gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac
     7981 acgtgatagc gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg
     8041 atggaatgac agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata
     8101 ttggtggcgg tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct
     8161 atgtggacta aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa
     8221 aaaatgagga aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg
     8281 gagtacctaa gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt
     8341 tatctatttc tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt
     8401 atcagtatgt agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact
     8461 tagtcgtatt gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga
     8521 gaaaagtata cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat
     8581 tgtttgaaaa aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt
     8641 ataaacagca aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa
     8701 aggaattctt tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg
     8761 ccgattgggt aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa
     8821 gtaagtattt ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat
     8881 attgatggaa cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg
     8941 gaaaaattac gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat
     9001 gcgcaagaga tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc
     9061 ggttttttag accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg
     9121 ttcgttcaag aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc
     9181 aagcgttctt cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct
     9241 gtcttgcctg aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca
     9301 tttttcgatc aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc
     9361 tggcatgaga acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg
     9421 cacttagcag aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa
     9481 aacgaccgtg aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca
     9541 gaagtacaag cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag
     9601 gcattgaaag agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt
     9661 aataagccca gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc
     9721 gcagatgcaa gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc
     9781 aagaaataag aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat
     9841 ttctgaagaa gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg
     9901 tcatagtccc atttttttat tttatttttc aaaactaaga aataccagga aagagttcct
     9961 tttgtttgac cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag
    10021 aagaggaatt tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag
    10081 agatgattac tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg
    10141 taaatggtga gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt
    10201 tgcaagacgg cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct
    10261 ttgagtttgt aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc
    10321 ctggacaagg gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc
    10381 aggctcgttc ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag
    10441 aagaagccag aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg
    10501 aaaaacaagc aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata
    10561 cacacgttca gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg
    10621 ttgggatgac aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa
    10681 agtttctgac tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa
    10741 gcggctgtat cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc
    10801 agatcaacga tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag
    10861 ccggaaattc aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc
    10921 attcgctaca aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga
    10981 gaaaaaatca aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca
    11041 gcagaaaaag aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg
    11101 cttgttgtag cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca
    11161 actatgatac aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac
    11221 taaaaatact cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt
    11281 tttgttctat cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc
    11341 acagcttttg gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat
    11401 gtgcggtgta cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta
    11461 taaagtagcg atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg
    11521 cgaagtgatc cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa
    11581 agacaacaat tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc
    11641 cgatttaagt acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa
    11701 tgaagcctct gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct
    11761 tcgtgaacag ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga
    11821 aaacgcggaa tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac
    11881 cggcaaacta ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa
    11941 agcagtagaa taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct
    12001 agaattaagc caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga
    12061 tgaaacaaaa acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat
    12121 ccaggcaaaa caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt
    12181 tgaacgtatc gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg
    12241 tcgagtagct ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga
    12301 acaagtgcca atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct
    12361 gctttcagaa atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga
    12421 tgatccgccg ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct
    12481 cgatatgtac cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa
    12541 agagcgtcaa gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta
    12601 ttatatagaa attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa
    12661 acaaacttta gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca
    12721 aatcctcgaa gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag
    12781 agaagaagtc aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt
    12841 agatgtgcta caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact
    12901 tgtcagtgac aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt
    12961 attaggacat caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt
    13021 gctgattaca ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac
    13081 tgttctgatg gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt
    13141 tgatcggatt tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt
    13201 tatggtagag atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat
    13261 tttgtttgac gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc
    13321 aatcatcgaa tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca
    13381 tgaactgacg gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt
    13441 tgaaaaagac ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag
    13501 ctacggcata catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc
    13561 agatatcctg catacgctag aaaatggcga taacggacac catactgttc cagctgaagt
    13621 agaagagaaa actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa
    13681 tcaagaccat atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga
    13741 attatccgaa aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat
    13801 gacgccaatg gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg
    13861 cggatatcga tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg
    13921 ggagaagtag tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac
    13981 gccggcagta ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg
    14041 attgataacg gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg
    14101 acaagtaaga tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg
    14161 gaagctttgc caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa
    14221 gaaaaacaag gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca
    14281 ccactgcgtc aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc
    14341 ttgaaatacg tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga
    14401 ctggcattga gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg
    14461 gcaactgctg gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc
    14521 gcaaaaaaaa tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt
    14581 tcattgcctg aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt
    14641 tttatcaaga acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg
    14701 gtcggtcgtt tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta
    14761 aatgttcatc cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta
    14821 attagtaacg ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat
    14881 aatctacggt ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat
    14941 ttgtcctacg cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga
    15001 gagacaggta cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat
    15061 aagtctgtgg aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca
    15121 gaaaaaacag cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa
    15181 acagtggaaa aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat
    15241 gaagaacaag cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca
    15301 ctccatcctg aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag
    15361 aaattagaaa cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg
    15421 cacggaacgt atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct
    15481 gcccaagagc gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat
    15541 ctgcaagaat tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta
    15601 aaagagcaaa aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac
    15661 agctttattg tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt
    15721 cgggagatga tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa
    15781 gcaacagcaa tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa
    15841 gcacaagcac gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc
    15901 catggccgtc cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga
    15961 atccaagacc cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc
    16021 caatcaccaa gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct
    16081 gctgatatcg atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg
    16141 gctgaagaaa aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt
    16201 gccagtgaca cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct
    16261 gaggctgaat tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt
    16321 gttttaaaaa caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat
    16381 cctttgacag acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca
    16441 ggggcatacg gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat
    16501 tacagtatcg taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa
    16561 acaaaaaagc ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt
    16621 gaaaagatta cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc
    16681 cgggcgaaca agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa
    16741 agcaacaata atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc
    16801 aatcagggtc tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc
    16861 ctttagttca acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag
    16921 aataccaatg gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata
    16981 gactttgccg tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac
    17041 tgggtcattt acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc
    17101 ttttgttgca actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt
    17161 tgcgccattt gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat
    17221 cttattcaaa attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc
    17281 aatgatcatt gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg
    17341 caaaccgcct actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc
    17401 taatccagag ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa
    17461 catagcaggt tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc
    17521 ttctttttta ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat
    17581 atttgataaa gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat
    17641 atcgatggca ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc
    17701 gaatacggca ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga
    17761 gatccagctt ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt
    17821 tggtaacaat gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg
    17881 gaagaagatt tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc
    17941 ttgataacca atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc
    18001 ggctgtggaa gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa
    18061 aacgattcct aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac
    18121 tggaagaaaa tggaaaattg cttcaccggg taaccacaaa aaggcattga caccattcca
    18181 aaacttcgag tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac
    18241 atttctgaat ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat
    18301 ttctgctaaa acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt
    18361 tccttgttct ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt
    18421 agaaacatcg tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac
    18481 gctaggtata tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg
    18541 catacgagtc gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa
    18601 cagcttctcg gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg
    18661 tctatgcaag ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt
    18721 attaaaaagt acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa
    18781 aaataggaac attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg
    18841 agtgagggaa aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt
    18901 ttagcgaaag aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt
    18961 tatggtgttt cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat
    19021 attcaaaaaa aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct
    19081 atttctggat tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg
    19141 atcatccata cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg
    19201 gagatcggtg cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt
    19261 atattagaca ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca
    19321 caaggatcga tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa
    19381 aaggagatca cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat
    19441 gacacttatg cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag
    19501 tattctgagt cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga
    19561 aaagtgtaaa tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga
    19621 taggatcaca aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact
    19681 gaaagaaaag ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc
    19741 atttagcggg aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg
    19801 tgaaccgtta ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag
    19861 caaaccaata acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg
    19921 aatagaagtt cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc
    19981 agtagatcaa ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata
    20041 tgaaaagatg gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata
    20101 cacaaagagc ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg
    20161 attgctattt gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcacagca tgacagcatt
    23641 gggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cactagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaagttt ttttgcgaaa actattttta tatcatatat atgtctaaaa tctatattat
    23881 aaaagaaatg ttgtttgatc agcttctctt cggtattagt tcaaaacaaa acggcaaagt
    23941 atatggagct actttgccgt tttgtttctc taatactcag gtcagtttat agacgctcaa
    24001 taaacggtgt tcaaaagcca gtttctcggt attaagtcaa atttatgcaa aaatgtgaga
    24061 agccattttc aaaaaatatt tcttaatact cgaaactgag cggctttttc acgacctctc
    24121 aataaacagt gttcaagaga cagcctatcg gcaataaggc tgaacgtctc tttcacaacc
    24181 tcttttatca atctgctact tcttctttct tagcgaaact ccaaatcagt ccgataacaa
    24241 aaccgataac tgctggtacg atccacccca tccccaattt gaaaaacggc aagtagcttt
    24301 ccgcaacata taaaagattt tgaacaatag gtgtttgttt gatagtttct gggcaagcgt
    24361 tcaacccatc aaaaatcgaa gcaatcaatg taaaataagt agtcattcga taaacagccg
    24421 tacgctgctt aaacaaagga ccaactaaca ctagtaaaat cagtgtcatt gctaatggat
    24481 agatgaacat caaaacaggc aacgaaaatt gaatgatatt cgtcaagcct acgtttgccg
    24541 ctaaacaagg aaggatacta gcaagtgcaa caaagaatgc gtaatttctt tgcggaaaca
    24601 aatctgtgaa tgtttctgca aaagctgtaa tcaaaccaat accggtcttc aagcaagcta
    24661 atataacgat aaatgctaat aagatactgc cataagtacc taaataatga tcagcaatct
    24721 gagccagcgt gatcccgcca ttttcactta gagcaaagct acctaagctc atagcaccta
    24781 aataagcgag caaagtataa atgattccca tcaatataat gctgatcgca ccagatttga
    24841 tcgtgtcttt agcgatttca gcaggttttg ttacacccat gttttggatt gttgtgacaa
    24901 tgatgatccc aaatgctaaa gcagcaagcg catctaatgt gttatatcct tgagtaaacc
    24961 ctgtgaaaaa agcatgctct tgataatttg gctgaatagg cgcttgattt acagaaccta
    25021 gtggattcaa aaaagcaagg agaagcaaag cacctaataa aaccaaaaat gcaggattca
    25081 ggaactttcc aacataatct aatatctttg tcggttttct tgaaaaccac caagccagca
    25141 caaaaaatac aatactgaaa attgctagat atagcgtctg tctgctagga tcgataaatg
    25201 gtgctaaacc aatctcgaaa gatgtggttg caaggcgagg taaagcaaaa aacggtccga
    25261 taactaagta aagcaagatg gtaaaaacca tcgcatatgt ttgatttatc cgttttgcta
    25321 attcatatac acctgagctt ttcgatacac caatggcaat cacccctaag aagggaagac
    25381 cgataccggt aaccaagaaa cctagattcg cccaaaaggt agcagcgcct gcttcttgac
    25441 ccaaatgaac gggaaagata agatttccag caccaaaaaa tagaccgaaa agcatggagc
    25501 ctataaaaag atagtcttta aatgataatt tttttgtcat acataactcc tttacggttt
    25561 ttttaaaagt aacaaaattt cgaaaaatat gcaacaattt tcagaaaatt tcctatataa
    25621 aacgacggtt atttaataac gtaagtgata aaataaaagc gctgaatcat ctgaggagga
    25681 atcatcgtga caaagtcgag attagaagca tttactgatg gagtggtagc cattgttttg
    25741 agagttcttg tattagagat caagatccct aatacatcta gctttcattc tttatgggtc
    25801 atccgaaata cattattagc ttataccatc agctttatat ttgttgcggt gatctgggtg
    25861 aaccatcatc gtatatttca gatggcagaa cgaattaatt accgagtggt ctggtcgaat
    25921 atctttttgc tcttttggct gactttatgt ccttctgtta ctagttgggt cgggcgtaac
    25981 cctgaagctt tttggcctga gatggcttat gtcttagtat acacgatgtg gagtttttct
    26041 tttggtatct tgatgaggca aatcatgaaa gcaaataaac cagattccca tgtcgtgaga
    26101 gttttgtcaa aggaccgtcg aagtcttatc tccatgatga ttaacttatg cttgattgcc
    26161 ggtgtctttt ttgtaccgtt gatcgggtta ttcggacgtt tttttgtatc tggtatttgg
    26221 attttttcct ataaaaaagc agatgcctat tatcagcggt tgtttccggg gaaatagaaa
    26281 agaggctggg acagaagctt ttaactccaa gaaataagcc gaaatttcac aaaaatttaa
    26341 gaagcaattt tcgtaaattc cttcttattt ctcgaagctg accacttctg tcacaactac
    26401 tttcttactt cttacgttca tatttcatat gatagattag taatagaagc aagaaccaca
    26461 caggtgttag taataaagcg attctcgtat cttttcctag gaacaagacg acacacacaa
    26521 aggccatgta aagaaatacc agataattac taaatgggta caacggcatt ttaaatgaat
    26581 gagctttttt gccgaggata cttttacgat atttcatgtg cgtgtagaca agcatactcc
    26641 agataaacaa gaaacaagta gtggcaatac tgcttactag tgtgaatact tcactaggca
    26701 tcacgtaatt caagataaca gaaatgaaaa tgacgatagt agaaaatgtc aaagcattcc
    26761 ctggcacatg atgtgttgtt aactttttga attttttagg ggcactgcct tcttgcgcta
    26821 aagaacgaag catacgtcct gtactatata ttgcactgtt gcaggcagaa gctgctgcac
    26881 ttaatacgac taaattgatc aaggaagcag caatcgtgat cccaatttcc gaaaatactt
    26941 ctacaaatgg actgttatct ggattcaagc tgttccatgg atagattgcc ataatgacaa
    27001 aaagagatcc taagtaaaat aagatgatcc tgataggaat attattgata gcttccggca
    27061 acactttttc aggattttct gtttctccag cgactaatcc aactaattct atcccagcaa
    27121 aagcaaaggt taccatttgg aaagctaaga taaatccttt tgcaccagtt ggaaagaatc
    27181 cgccatgaga ccatagattc gtgatactgg ctgtgccaat atctgtcgta tagtgggtga
    27241 ggatcatata agctcctacg aggataaagg caatgatcgc tacaactttg atcaatgcaa
    27301 accaaaactc taactcacca aacaatgaga cagccaccat attcaagcaa agaagaagac
    27361 ctaatgcaat cagttcagga agccactgag gaacaccagg cgcccagtag cgtacataca
    27421 ttccgatggc tgttaaatcg gccattgcaa tcgataccca gcagaaccaa tacgtccagc
    27481 cagtgatgaa agccgctttt ttgccaagat attctgcaac aaaatccaga aaagaatggt
    27541 tattggtgtt tgataacaga agttcgccta acgcacgcat aatgaaaaaa cagatgcatc
    27601 cagtaataag ataggcgagc aatatcgaag ggccagctag ctggatagac tttccggaac
    27661 ctaaaaacaa ccccgttcca atcgctccgc caatagaaat cagttggaca tgtctatttt
    27721 tcagtccacg ctgcagttct tgctcttcat tcatttttaa atcatcctaa ctaaaaaagt
    27781 ttaattactt ccatattaaa agagttttct gaaaaacaca actaagattc caaaattttc
    27841 agaaatttac cttttatgag taattcataa aaaagaactg cggtaaacac cgcagctctt
    27901 tgtcccaatc agctattgat cctaagcatt taaaatacgt gaaaggaatt cttttgtacg
    27961 ttcttctttc ggatggacaa agatatcttc tggtgtacct tcttctgcaa tcacaccttt
    28021 atccataaaa atgacacggt cagatacatc ttttgcaaat tccatctcat gcgtcacgat
    28081 aagcattgtc aagccagtat gtgctaagtc tttgatcgta ttaagcactt cgccaaccat
    28141 ttcagggtct aacgccgaag taggttcgtc gaatagcaat acatctggat tcattgataa
    28201 tgcccgagca attgcgacac gctgtttctg tccaccagat aattgtgctg gtttggcttc
    28261 gatataacga tccataccaa ctttttccag attttcgatt gctacttttt tggcagtttc
    28321 tttatctcgt ttcaggacag ttgtttgacc agacatacag ttttccaaga cattcatatt
    28381 gttgaacagg ttgaaggatt ggaaaaccat acctagattc gttcgatatt taggtaaatt
    28441 atatttagga gctaatacat tttctccatt ataaatgatc tcgccgcctg ttggtttttc
    28501 cagtaaattg atacagcgca agaaagtaga tttaccagaa ccggaagaac cgatgatcgt
    28561 cacaacttca cctttattga ctgttacgct gatatctttc aatacttcat tttcaccgaa
    28621 gctttttctt agatgtttga tttcaataat tttttcattc atgattcttc ctccttattc
    28681 ctgcaaattt gaattgtcga tttcttcaag cttggtataa gctgaaggac catcgatttt
    28741 cttttctacc gcccgcagga ttctggtgat cgtaaaggtc atgactaagt agatgatccc
    28801 gacgatcgta aatgtttgga agaattggaa attcgcaccg gaagcagagt ttccttggaa
    28861 gaacaaatca gctacgccga ttacacttaa aactgctgta tctttgatat tgataacaaa
    28921 ctcatttcct gttgctggca agatattccg taaaacttgt ggaataacaa cttttctcat
    28981 cgtttggcca tgggtcatac caatggcttg cgcagcttcg aactgccctt catctactgc
    29041 aaaaatcccc ccacgaacga tctctgtcat gtaagctcca gtattgagag agacaataaa
    29101 caaagcggca atcgttcggt tcaatgaaat gccaaaagcg agtgccagac cgtagaagat
    29161 gaccattgct tgtaccatca tcggtgttcc gcggaatact tcgacataga tagaaagaag
    29221 tgcatttccg attttttgga agaagcgagt cagtgcattt cctgattcag gtaccgaacg
    29281 gaagacacca atcagtaatc caagtgtagt accgacaact gtcccgatca atgcgatgaa
    29341 caaggtaagt ccagcacctc gtaagaacat attgccgtat tgtttccaaa tcgtagtgaa
    29401 atcagaaatg atgccaggtt tttcttcact atcagttgca gcaggctgat ctttgactgc
    29461 ttggtccata attttggttc gttcatcgtt agagatgcca gaaagaatct ggtttacttt
    29521 ttggatatcc gggtcgcctt tacgcatacc aacagaaatc tgaacatctt ccgggtttgt
    29581 ctggaagcca tctgcaccgc tgaattcaag catttccaag tctttgttca cactagttgc
    29641 cgttacacct tccggacgtt cgctgacata accatcgatc attccagaag ctaaagctgt
    29701 tctcattgct gagaaattat ccattgcttg ttgtttctgc acatctggta tctgatcgat
    29761 cacagtatag tggaatgtat ttaactgagc agtaatcttt gctccagaaa gatctgctaa
    29821 actttttgct tttgcatatt tgctatcttt ttgaactact actactaatt gtgattcgta
    29881 ataaggatcg gtaaaatcaa tttcttttcg tcgttcagca gtagggctca ttccggcgat
    29941 gatcgcgtcg atcttgcctg attgaagggc aggagccaga ccatcccatt tcgtttggac
    30001 gatgactaat tttttcccta aaccatctgc tactttttta gcgatttgaa catcataacc
    30061 gccggcgtaa ctattttggc cttgaattgg caaggcatta ttctcatctg tttgttgaga
    30121 ccagttgaag ggtgcatacc cagcctccat acctacgcga aactcatcgc tcggtgtttt
    30181 ttcatctgca tttgccagag atcccacact gaatagtgag aagacaaaag caaatagtac
    30241 ggcaactgaa accatatttt ttttcatttt tttctccctt tctgattata tgatacacga
    30301 gcggtctaga tgaaatgcgg taaagcttta tctgaaaaaa taaaaagcga ccgatttata
    30361 gatataaaaa ggccgctaaa attccataag gtgataaacc tctcacaaaa catagcgcaa
    30421 cttagcatca ctgctaagac agtccgcaag ctcttaactt gcgtcccaac atacactcca
    30481 agcaaaaaag tgcacatttc ggcgatcctc cctattcctg cttctccatg tttgcttcac
    30541 tccacagggt taatgattct cgcgacctct acctcattga ttgaggcatc tcgtattcag
    30601 ttatttatac aaaaaaagtt tacgatactc gagaggcttt gtcaatctat aactgctgtt
    30661 ttttgaaaaa atactgataa atatagaaat ctttactttt accgaaaaaa caatcaaaat
    30721 gtgaatcatc tatccattgc aaacgatagt ataattatac acaaaaatgt atgtaataca
    30781 ataaaaaaag aactagaaca gaaaatttcc tgtgtccagt tccatctcga tcatttaagc
    30841 tgccgctttc tttggctcac gtcctaggat cgcttgcaaa agaacaacga cgccataaat
    30901 ggctaatatt agataaatca aacttgagta ttgggtgatt ccccagcccc atgttcgata
    30961 tacggctaat gtaatggcta aaacaattgc ggcaatcacg ttgaataaag caaaagccca
    31021 aagatttcca ttttctttgc gtacaagata aaaaacagag aaataaacgc ttaacgctaa
    31081 ccaggcgata caagccagaa taacgcccca ataaataaag aatggtaaca tatcgattca
    31141 cctcactttt atacagcagt attgtaacac gttttcattc ttttgtcagt gaacattgtg
    31201 ataaattgtt caaatgccca taacactttt ttattcccat ttttctgact tttcaacaat
    31261 aaatttgttc gagtatgggc tataatggaa agtgaggtga caaaacatga aacaattaac
    31321 agtagacgaa gcagcaaaag agatattagc ttatcagcaa attacatttt tgaccggtgc
    31381 aggggtatcc acaccttctg gagtgccaga ctatcgatct ttgtcaggaa tctaccacgg
    31441 gatggagcag ccggaatact tgctgagtca tcaagcaatg gtgaatgaac cggataaatt
    31501 ctatcaattt gtcaaaaaga tttatcatcc tgaagcaaaa cccaatatca ttcatttgga
    31561 aatggcacat ctagcgaaag aaaaaaatgt ttgggttgtt tcccaaaaca tcgacggttt
    31621 gcacgcaaag gctaaaagcc cgcaactcgt caattttcat ggaagtttgt atcaatgtca
    31681 ttgtcgaaaa tgtcaacaaa cggtagactg gaaagaatat cttcacagcg acaaacatca
    31741 agcatgcgga ggacaaatac gcccagacat cgtgttatat ggtgaagggt ttcaagatgg
    31801 agtcatggag caggcggctt atgccgtcag ccaagcagag ctgatcgtca ttgttggaac
    31861 gagttttcaa gttcatccgt tttgtgatct ggtacagttt cgccagccgt cagccaaaat
    31921 cttagtaatc aatcaaacgc ctgtttattt agcggagcct tatacgttta ttcaagaaga
    31981 cggagcggtt gttttcaaaa aaatacaaga attaggagca gattatgact gaattcaaaa
    32041 ccgaaaaaga aaaaatgatt gcaggcgagc tttattttgc caatgatcct gagctggttg
    32101 ccgaccgtat gtttgcaaga agtcaaagcc aaatcatcaa ccaagcagaa tcagcggaac
    32161 tgcgatccca attgttgaaa gagacttttg gccgtacagg gaaaaaaatc tatatggagc
    32221 cagttatcaa ttttgattac ggatataata tatttgttgg ggagaatttt tatgcaaatt
    32281 tcaattgtac atttttagat gtcagcacga ttgaaatcgg tgataactgc atgttcgctc
    32341 cgaatgtcca gctttacacg gcgacgcatc cactacatcc agtgaaacgt aacagcggtc
    32401 tggagtacgc aaaacccatt aaaatcggta ataatgtttg gttaggcgga ggagttatcg
    32461 tcacgccggg tgtcactcta ggggacaacg tagtagtcgg cgcaggttcg gttgtgacca
    32521 aatcttttcc cgacaatgta gtgattgcag gaaatcctgc tcgtatcatc aagacagtag
    32581 aggaagaact aacagaagag tctcttgaaa cattacgtca taagatcgat atgatcgatc
    32641 gagagttgat tgctttatta gaaaaaagaa tggatacggt aactaaaata ggacaagtga
    32701 aaaaagaaga aaaccaagca gtttatgatg caaaaagaga gcagcaagta ttggataaag
    32761 ttgttagtct gctgaaaaat aagggatata aggaaacaat aacagatacg tatgttgatt
    32821 tgatgaaaca ctcgcgcgaa taccaaaaca aaatgaagga ggaataagtg tgatcgaagg
    32881 agagacacgg cgaaaacaaa tcatgcaaac cttggcaaat acagaaaaac cagtgagtgc
    32941 tagcaagttt gcgaaaactt ttggagtcag ccgtcagatc attgtaggcg atattgcttt
    33001 actacgagct gcaggtaaaa gtatcgtggc aacagcaaga ggttatatcc tcgaaacaga
    33061 agaaaccaat actgggcaca tcagtaaaat cgctgtccag catggaaaag atcaaacaga
    33121 agaagaactg agactaatcg ttgaaaatgg tggtgaaatc attgatgtaa ttgtggaaca
    33181 tcccctttac ggtgagttag caggaacttt gcacatcaaa acgccacaag atatcgattc
    33241 ctttatgaga cgttatcaaa aaagtaatgc tactttgtta tccgaattaa caggcggcat
    33301 ccatctgcat acgatccgct acccagaaaa gcatatgctg aaaaacatca aacaaaaact
    33361 agctgaagca ggaatcctct acgaaggata acatcgtagc tgctactttt tatcctagaa
    33421 actattctat catctctgag ataaacaccc atatggaaga aataagaaaa aataagaaaa
    33481 gatgcgtatc caatacacag aattttttgg aattgcgatt tctagatgtc tatctaaatt
    33541 tcgattagtg gagaaacata aaaaagggaa gtgcagcttt tgagcactcc ccttttttat
    33601 aaagctttct tgtagcatag tatcgaagga acctgccaat tctctactcg atcaccaata
    33661 cgccttcttt tagtgcaaat ggattttgat cgttgatgtg gtcatagaac atcacaccgt
    33721 tgatatggtc gatttcatgt tgaacgacga tcgattcata attcttcaaa cgaatcttgt
    33781 gtttttcacc attcatatca taataagaca cagtgatttt ggcatggcga acaacatatc
    33841 ctggtacttc tcgatcaaca gataaacagc cttcaccttc ccctaaacaa gcatcttgaa
    33901 cagaatggct caaaatttta ggattataca taacagtact tagagaaggt ccatctgcct
    33961 ctgggtcagg acttggtacg tgaacagcaa tgattctttt agaaatatct aattgaggag
    34021 cagctaagcc aacaccgcct cgtaagtgta gttcttcagc tttgattgga tcttggctgt
    34081 tttttaagaa ctcaagcatc tcttttccta aagagatatc ttcttcgctt aatggaagag
    34141 aaacttcttt tgcaacttcg cgtaaggtcg gatttccttc acgaatgata tcatccattg
    34201 taatcatgga atatgtaccc ctttcttaaa agactgtgtt tcaagtctat tttcgcatta
    34261 tagtttacca caaaaatgga aaagtagtag taagattgtt tgaaaactac cttttcttaa
    34321 tgattaacta cttgattttc aacccggttt caggtaaagt atagctgtgt gctctaggca
    34381 catgacctgc cacttggtta agcgaatcac caacgtttta ctcagtcgca ggggaataat
    34441 cgaaagaggt gaaagaaatg gcaatttcaa aagaacgcaa gaatgaaatc atcaacgaat
    34501 acgctcgcca tgaaggggat actggttctc cagaagtaca aatcgctgta ttaactgaag
    34561 aaatcaacca cttgaatgaa catgcacgcg tgcacaaaaa agaccatcat tcataccgcg
    34621 gcctaatgaa aaaagttggt caccgccgta acttgttagc ttacttacgt aaaactgacg
    34681 ttcaacgtta ccgcgaattg atcaaacgtt taggcttgcg tcgttaattt tagtcaaaaa
    34741 gagtgggatt cacatgaatc tcactttttt tactcgtata tcaattaagt aaaattccgt
    34801 gatcaagcta gatggactcc tactaaccaa atgaaagctg ctcaaaagac ggctttcggc
    34861 agttttcatt tgtttagtag cgtcttgctt tcacgagaag gaaaaggaga agttatgtca
    34921 gaaaaacaag tattcaaaac gacatggggc ggccgtccct tacaaatcga agtcggtcag
    34981 ctagcaaaac aagcaaacgg agccgtttta gtccgttatg gagatacagt agtcttaagt
    35041 gcagctgtgg cctctaaaga agcaaaagat acagactttt tcccattaac gatcaattat
    35101 gaagaaaaaa tgtatgcagc agggaaaatc cctggaggtt tcatcaaacg agaaggccgt
    35161 ccaagtacgg aagcaacatt gactgcccgt ttgatcgacc gtccaattcg cccgatgttt
    35221 gcagaaggct tccgtaatga agtccaagta acgaacatcg tgatgagtgt agaaacagac
    35281 tgctcgccag ctatggcagc aatgctaggt tcttctttag cactatcaat ctcagatatc
    35341 ccatttgacg gcccaatcgc aggcgtagaa gttggtcgtg taaatggcga gtacgtcttg
    35401 aatccaacag tagaacaagc agaacaaaca gatatcgaat tgactgttgc cggaacgaaa
    35461 caagccatca atatggttga aagcggcgcg aaagaagttt cagaagaaga catgcttggt
    35521 gcattgctgt ttggttttga cgctatcaaa gagttagttg ctttccaaga agaaatcgtt
    35581 caagcagtag ggaaagaaaa aatggaagtg actttactgc aagttgatga agtattgaaa
    35641 aaagaaatct ttgatgcttc ttacgctaca atgaaagcag cagtaatgac tgaagaaaaa
    35701 cttgctcgcg aagataatat cgagcaggtg aagatcgata tccgcgaagc ttatgctgag
    35761 aaatttgcag gtcatgaaga tgaagatcac ttgttgaaag aagttaaaca aatcacagaa
    35821 gatcttgaaa aagatgtcgt acgtgaattg atcaccatcg ataagatccg tcctgacggg
    35881 cgtaaattgg atgaaatccg tccattgtca tcagaggtca gcttattgcc acgtgtacat
    35941 ggatcaggtt tgttcacacg aggacaaaca caagctttat cagcttgtac actcgcacct
    36001 ctaggagagc accaaatcat tgatggttta ggggtggaag tcagcaaacg attcatccac
    36061 cactacaatt tccctcaatt ttctgttggt tctacaggac gtgcaggctc tccagggcgt
    36121 cgggaaatcg gacatggcgc attaggtgaa cgtgcgttag cacaagtaat cccttcagaa
    36181 gaagaatttc cttatacgat ccgtttagta gcagaagtat tggaatcaaa tggttcttct
    36241 tcccaagcaa gtatctgtgc tggcacatta gcattgatgg atgcaggtgt accaatcaaa
    36301 gcgccagtcg ccggtattgc gatgggactt gtttctgatg gtgaaaacta tacgatccta
    36361 actgatatcc aagggctgga agatcatctt ggcgatatgg actttaaagt tgccggtaca
    36421 aaagatggta tcactgcttt acagatggat atcaagattc aaggaatcac agaacaaatc
    36481 ctaactgaag cattaactca agcaaaacaa gcacgtatgg aaatcttaga agaattgact
    36541 tcaacgattg ctgctccacg tgaagaatta agccaatatg caccaaaaat cgaaatgatc
    36601 cagatcgaac ctgctaaaat caaagatgtt atcggtaaag gcggcgatac gatcaacgga
    36661 atcatcgatg aaactggtgt gaaaatcgat atcgatcaag atggaaaagt aagtattgct
    36721 tcagctgatg cagaaatgat caaaaaagct atcaagatca tcgaagattt gaccaaagaa
    36781 gtcaaagttg gtgaagttta tctagggaaa gttgtccgta tcgaaaaatt cggtgcattc
    36841 gtcaacttga tcaaaggaaa agatggactt gtccatattt cccaattagc aaacgatcgt
    36901 gtcaataaag tcgaagatgt tgttaaacta ggtgatgaga tccttgtgaa agtaactgaa
    36961 atcgataaac aaggacgcgt aaatctgtca agaaaagcaa tgttgaacga agatggttca
    37021 acgaaaaatg aagaaaaata atttaattca taggaataat gtacttgtga tcgtgaaggt
    37081 gacaggggga caataattat tcgaaaaaag gggactgtga caaaagccgt gtcacagtcc
    37141 ttttttttcg aataaacggt gttcaaaagc ttgcatctgc ggtaataagt ccagccaagt
    37201 taaaaacatt aggagctgtt tttatttggc tgttcttatt acttgatgca gaacagcttt
    37261 tttacaacct ctccaataaa cgatgttcaa tcagctgtcc ctcgatatta gctcaaaaaa
    37321 cggcaaaata tgaggaacta tttttccgtt tgtttctcta atactcaggt caaaccgctg
    37381 atttcacaac ctctgattca cggtgttcca gaagcagctt ctacggaaat aagctgaaca
    37441 cttttgttac aacttctttt tttctggagt ttcttggcgc atatttttgg agtccttctg
    37501 aataaagcgt aaaataaaag tgagaaatat ggataaagga gggaaaggag atgctgaatt
    37561 ttttatggtc gttatttatc ggcggtatat taggtttgat agctggcgca attttaggaa
    37621 aggaagtccc gggaggcgta tctggaaata tcattatcgg ttttttaggt agttggctcg
    37681 gcgaattttt actaggacca ctgggaccgg aactcggcgg tttttatttg ataccagcat
    37741 tattgggtgc aattttttgc cttgctcttt attcatttgt ggcaagacgt atcagagaac
    37801 gtccaaagaa agaataattt tattcaaata agttgacact tcagtgtgtt acttggataa
    37861 ttagaagcaa tttaggaaag cgggtgtcat ggataagaat atcatctatc attcaagctt
    37921 acctaaagga tatccatata acaagaaatg agggaaaaac gtggcaacaa cgcacaatac
    37981 caaaaagata tcaatgactg gcctgcttgt agcgatggga gtcgtctacg gagacatcgg
    38041 gacaagtccg ctttacgtta tgaaatcgat tgttgaagat aatggcggat tgtcaggaat
    38101 caatcctgat tttgttatcg gatcagtctc attgattttt tggacattga ctctactgac
    38161 aacaatcaaa tatgtcgtga ttgcattgaa tgcagataac catggtgaag gtggaatttt
    38221 ctcactctac acacttgtcc gaaaaggtgg gaaatatttg atcattcctg caatgatcgg
    38281 aggagctgcc ttactagcag atggggtatt gacccctgct gtgacggtaa cgactgcgat
    38341 tgaaggcttg cgaggaattc cgcagttttt tgaccggttc ggtaataacc agaacgtgat
    38401 cgtcattatc actttagtta ttatttttgt tttattcatg gtccaacgct ttggtacaga
    38461 tattgtcgga aaagcattcg gaccaatcat gttcgcttgg tttacttttt taggcgtaat
    38521 gggattaatg aacttcagtc aagactggac agttatccgt gcactgaatc cttattatgc
    38581 tatccagctg ctttttagtg cagataacaa attaggcttg ttcattcttg gaaatatttt
    38641 cctggctacg acaggtgcag aggcgcttta ttccgatctt ggacatgtcg gcaaacgaaa
    38701 tattcgtctg agctggcctt acgtcaaaat ttgtttggtt atcaattatt ttgggcaggc
    38761 tgcgtggttg ttgaatgttt atcaaaaccc tgaagcacag caaatcaaga acctgaatcc
    38821 attcttccaa atgatgcctc aaagttggat cgtgatcggc gttgcttttg caacagtcgc
    38881 tgcagtcatt gcttcgcaag cattgattac aggttcgttt acgctagttt cagaagcaat
    38941 caagttgaaa ctgctgcctc ggttaaagat catgtatcct gggaacagta tcgggcaaat
    39001 gtatatccca gcagtcaatc tgattttatg gatcgcctgt tctctagtgg ttgtcacatt
    39061 ccgaacgtct catcatatgg aagctgctta cggtctatcg atcactgtga cgatgttgat
    39121 gacaacagca ctgctttact tttatcttat ccaaaatggg cattctcgtt ggcttgcata
    39181 tttagttacc tttttcttcg gtgcgataga agtcgttttc tttatctcaa gtgttgtcaa
    39241 attcttccga ggcggttttg tagccgttct gattggtttg atcatcttag tcgtgatgtt
    39301 tatttgggaa caagggaaca ttattcgcga atcgtcaacc gaggatgtgt ctttgagaga
    39361 ttatatcccg cagcttagag aattacgtga tgatacttct ttaccaatct atcagacaaa
    39421 tgtggtcttc ttggttcctg atatggctga agataaagtt ggccgacagt tcatctattc
    39481 gattttagat aaacggccta aaagagcacg agtctattgg tttgttcatg tggaagtgac
    39541 ggatgagcca tatacgaaag aatatcaagt agatatgatg gacactgatt ttattgtcca
    39601 agtgaatctg ttcttaggtt tcagggtcca acaggaaatc aacgtatatg ttcgccaagt
    39661 catccatgat ttgatgaaac aaggccgttt gccaaaacag ccacaaagat actctctgac
    39721 accagggcga gaagttggcg atttccaatt tgtcctgatt gatgaagtag tttccaatgt
    39781 gacaactcta ggaaaatggc aacgtcaaat catgcaggca aaactggcaa tcaaaaaaat
    39841 cgctacctcg ccagaaacat ggtttgggct agagtacagc gaagtaaaac atgaaactgt
    39901 tccgcttatc attggaaata ctcggaaaac atggttgaaa gagcggttgt gaaagtagcg
    39961 ctttgacctg aactaatgtc gaatgtcagc tacttgaaca ccgtttatca gaggtcatga
    40021 aaaagctgta ctgcaacaag cagtaagaac gagcagataa aaacagcttc tcatgttttt
    40081 catctgtttg ggcttaatgc cgtagatgca agcttttgaa taccgttttt atcagaggtc
    40141 atgaaaaagc tgtttagcaa caagtaacgc aatgattttg aagtgataag gagatgtggc
    40201 tgaaaaatgc cgcatctcct tttttattcc taaatatgaa tacgcattat tttcaatctt
    40261 tttgtagaaa aagggtacaa tagaaaaaga gaaaggcggg agaatatggt tatcaatttc
    40321 attattttat ttttgatgat tgcaattact tcattttttg tagcaagtga atttgcttta
    40381 gtgaaaatca gacgatcaag attggaacaa ctagaaaagg aaaatgtaaa gaacgccaag
    40441 ctagctcttc atgttacaca ccatttagat aactatttat cagctagtca attaggaatt
    40501 acgctaaccg gtttgatcat cgggtgggtc ggtgaaggat ctgtcgcggc tttactagaa
    40561 ccagtgatcg gtaaactacc ttttagttcg gctattagca gtacaatctc tgtggcgctg
    40621 ggatttattt tagttacgta tatcgatgtg gttattggcg aactgcttcc taagagctat
    40681 agtatcgtca atacggagaa ggtcgtcttg ttcgtagtta aaccacttca ttatttttat
    40741 aaagtaatgt ttccttttat ttgggtattg aatcattcag ctgcagggct agggaagcta
    40801 ttaggtgtgc gtctcgtatc tgaaggagaa gagacattgt ctcaagaaga gctgacatta
    40861 gtcgcattga attcttatga aaaaggagag ttgaccaaag aagaatatta ttatttggaa
    40921 aacgtgtttg aatttgatga taccttggca aaagatatac aagtagaccg tacgtccatg
    40981 caagtattcg aagcttcaga aaccgtcaaa gaagcgataa aagcttcgat tgaacaagga
    41041 catactcgct atccggttat cttagaatca aaagacaatg ttttaggtta tgtcaccttg
    41101 ccagatttga tcaagcaatc ttataaagat gaccagctga cagtagaaca gttgattgaa
    41161 gagccgatcg taacaactga aacgatccct ataaaaaaat tattgacgat catgcgaaaa
    41221 aagggtaagc atattgctat cttaaaagat gaatacggag ggacaagcgg cttagtgacg
    41281 attgaagata ttttagaaga aatcgtcggg gaaatccgag atgagacaga tttggacgaa
    41341 gcattgatag cggaacagtc agatggctct tatatcatct ccggcaaact aacattagat
    41401 gatttccagc gttattttca tgtagagatt ccagagtttg aagaaacgaa ttttactaca
    41461 cttgcgggct ttgcttctag ccgatataaa gaaataaaag caggaacaat cattgagatt
    41521 gcatcattcc gtttcacggt attagaatac cagcatgcac atatcgatta tttcaaagta
    41581 gagtccacgg aaagaaaaac agaataaaag aaaaaaggct gtgacatttt ttgtcacagc
    41641 ctttttgtta tctaaaaaac ctgttttcgg taaacgaaga agatattttc aataaaagtt
    41701 ttcattttta gccgcaacga tttcttttaa tcaaggctat cttgcttctg catgttctaa
    41761 tgtgaaatgt tcctcttcac ccatgtgttt caattgtttc atcgaacgca tataagagta
    41821 aagcaacacg gcaacagaac cgatccaagc taaaggagaa gctgctgctg ctcctgggta
    41881 tccccacatt cctgtaagaa cgatagctgc aaaagaacgc ataagcaatt ccatcatacc
    41941 ggcgatcgta gggatcttgc tttgtccaag cccttgaagt gtgtagcgta aaatgaacag
    42001 gactgctaag atccagtaaa gagacccatt gatattgaag taggtttgtg ctaattcaaa
    42061 tacacgtgtt tctgatgggt taacaaacaa ttgaacaaag aaatgaccga agaaaatgac
    42121 gatagcacct gctaagagac taaatccgac actcatcagt aaagtttgac gtaccccttg
    42181 caagattcgg ccatattctt tcgcaccata gttttgtgca gtgaaagttg ccattgcaat
    42241 accaaatgac atcatcggct gatttgcaaa ttggtcgata cgaccagcag cggcttgagc
    42301 agctacgaca tctgtcccta gactatttag tgctgcttgt aacacgatag caccaacagc
    42361 gatgatcgaa gattgaaacg ccattggcaa agcagcattt aggtgtacag caaactcttc
    42421 tttttcaaat ttgaaatctt ttttgcgtaa ctgtaacaaa ggcatttttt tcttgatata
    42481 cactagacac agtacgctgg aagaaacttg tgcgattact gtagcaatag ctgcaccttc
    42541 cacacccatg ccaaaataga taataaagat caaatcaagt acgacgttga tgatgaccgc
    42601 aatgatcaga aagaatagtg gtgtgcggct gtcaccaagt gcgcgaatga cattagaaag
    42661 caaattgaaa ctgactgatg caaagatccc taataaaata attgaaataa atgtttgtgc
    42721 ttgatcaagt atttcaggag gagtttgcat caattgaagc atcggacgaa taaacaggag
    42781 acttaggaca gttaaaatca cagtgacgac aagactaatg acaacactag cagcaaaact
    42841 tttcttcaga ccccgataat cttttgcacc gtaacgttgt gcggtaataa tggctaaacc
    42901 agctgttaaa ccttgggcaa agccaatgat caaaaatgtc aggcttccag ttgcaccaac
    42961 cgctgccagc gcatttttac ctagcgtctg acccacgatg atcatatcga tcatattgta
    43021 gaactgctga aaaacatttc cgatcagtaa aggaacagtg aacatcaaaa tcagtttagc
    43081 ggggcttcct tttgttaaat cgcgcatctt ttaaactcct tatatcttta aaatttagtt
    43141 agtagtatat agcgtttatc ctgagaatac caattagaaa tcaatgataa tttatgaaac
    43201 tccataaaaa gaagccaaga attgagtcaa agaatcaaca acttggcctg gtctgtaaaa
    43261 taagggacat ccacgtttat ctatcacctt aatattgtct aatctcactt ggtaaaagga
    43321 tcgtttctct cgtaccgtca tcataggcgt atacttgagc aggaaattgg ttcgaatagg
    43381 caaacggcaa atcaatatcc atttccacat tgcttcctgc ttgagaaaaa tgcatcgtca
    43441 cttttccacg attttcgatc aaatcaaagg ttaatatatt ttctaatgga atgactccct
    43501 taagatctag gtcaataata aaccatatac tgtcaatcaa ttcatctggc aaacttgata
    43561 cgacaccaac tgaagcgtaa cggttgcggc tgctatcaaa actttcaaac atctgtttaa
    43621 cctccttcga atcaacgaat gttttatttt tataattaat cctaggataa actagaaata
    43681 cttacttcaa cgagggttca ttctaataaa gaatcaggaa aaatgcaaca ataattgaat
    43741 actttttttc aaagtataaa tttttataaa ggtacgataa aagtatgcga ggaaaagctt
    43801 ggtaaattag gatttttcgt ttgtaaagcc atttacaaaa gtggaagccc catatgaaaa
    43861 taaacgatta gaaataaaaa aggcgtgtta aaagctgctg acccgccgct tctaacacca
    43921 cctgattgtt tcagtattat tcttctgttg aaccgatcac ttctggttcg ccaccttcac
    43981 ctgtgctttc ttcttcttca ctttgagcga ctacagcagc gatttgctct tcactgtcgg
    44041 tcacgaattt gtaatcgtcg ttttttggaa gatcggctac tgtaatagaa tcacctaatt
    44101 ccaagtttgt cacgtcaact tcaattcgtt caggcaattt gtctggtgta gcagatacga
    44161 ctactgtata caagttttga gctaacactc caccagattt agcacccact gattcgccaa
    44221 caagaacgac ttctgtttcg acttctgttt cttccgacat gtttacagat agaaattctg
    44281 catgttcgaa atgattggta aaagtgttcg tttggatctt gtgaaccaat gtattgactt
    44341 tttgtccatc gatgtccatc gtgatgactg tgttcgctcc atgttcacgc aacaatttgc
    44401 ttagtgtcaa accatcgaat gagatagggg tactttctac tttataccca taaacaacag
    44461 ctggaacttt cccttcgtga cgaagtttgt ttcttaatga acggggacgt acttctcttt
    44521 tacttacttc taatgatact gacataacca aaattcctcc ttaaaatgtg actgtctgct
    44581 ttggtaacgg acagatttta tttaagtgaa ttctaaaggc taatctcgtg cacatcatcg
    44641 aaggcagggc gcttaaaaaa gcgcaaaagg agagatgcgc gcatctcccc ttagaaagtc
    44701 aggattcaac ttttctccac caggtcatta cgctgtgtat gagaaatcca attcacttta
    44761 ctatttaacc gtaacgtgaa ctgttaatta agtcaaggaa taactatgat gatgtatttg
    44821 caagcaagaa tattcaaggt ataattaatt agtagtaata agaaaggaaa cagcatgcgt
    44881 ttagataaat taatagaaga aaaattagaa acgacacgca aggaaatgaa gcggctgttt
    44941 gctttgaagc aagtgatgat agatggcaca gtcgaatttc gacaaaatcg aaatgtagat
    45001 agtttactgc atcaaatcga agtagcaggt gaacacttag aaacaaatga gtcctattat
    45061 cttctcaata aacctgaaaa agctgttaca gctgtatcag atccagaaaa gacgacagta
    45121 atcgatctga ttgcaagtgc cgatcgtttc caaccattat atccagtggg aagactagat
    45181 agagatacaa caggactatt gctgatcact tcgaatggac aattgggata tgaaatgcta
    45241 cttccagaaa aaaaggtttc aaagacttat caagtagttg tgaacgaaag ggtgacaccg
    45301 gcagacgtaa cagcatttga aaatggaatc gtattcgctg atgggtatca atgtaagccg
    45361 gctgatttaa aaatactcaa agcagacaag caccaaagta cggttttatt gacgatccaa
    45421 gaaggaaaat tccatcaagt caaaaagatg ttcttagccc aaggaaagaa agtgaccgca
    45481 ttgaaacggc taagcatggg accattggaa ttagatgaac agctaggagt aggcgagtat
    45541 cgatcgttga cattagcaga gatgaaaaag ttaagtattt attttaaata ggaggtcaaa
    45601 aagatgaaat ataaaacttt attgtttgat gtagatgata cattgttaga ttttcaatta
    45661 actgaagcca atgctttaag tgctttgttt gcagaacaag gaatcacatt gacaccagaa
    45721 atcgaaacca gctataaggc tttgaatcat catttatggc aggagtttga aaaaggcaga
    45781 ctatcacgag aagaaataat aggcagtcgt tttgggttac ttttccagca atttgggaaa
    45841 acagtagata gtgatcaaat ggaaaaacgc taccgccact acttgaacca aggtcatgat
    45901 cttgttccag gaagtctaga aatcctgaaa aaggtccatc cgcatgctga tctttatatt
    45961 gtgacgaacg gtgtgtcgca cacgcaacat cggcgattaa cagatgcagg aatgcttgat
    46021 tacttcaagg atatctttgt ctcagaagct gtcggagcgc aaaagccgat gaaagaattt
    46081 tttgatcatg tcttttccca cattcctaat tttgataaaa agcaaactgt gatcattggt
    46141 gattctttga cttctgatat caaaggagga aatatggcag ggatcgatac gatttggttc
    46201 aatagaaata aattaccaga aatcgaagaa atccagccta cttatcgaat cgattcatta
    46261 gaggaacttt attcattatt ggaaattgaa aaggattaat tttcagaaaa atatagcatt
    46321 ttcgtgtttt ttcgctataa tagattagaa tgaaaaaacg gatacgaaag aggttttagt
    46381 caatgacaaa aagcaagcca attatcattg gtgtgacggg tggatccgga agcggaaaga
    46441 caagtgtcag ccgtgcgatt ttcaacaact tcccggacca ttccatcatg atgcttgaac
    46501 aagattctta ttacaaggat cagagccatt tgagttttga agaacgattg aacacaaatt
    46561 acgatcaccc atttgccttt gataatgatc tgctgattca gcatgtaggc gacttactga
    46621 actataaagc cattgaaaaa cccgtgtatg actatgtagc gcatacaaga agtcaggcaa
    46681 cgatcattca ggaaccaaaa gaagtgatca ttctagaagg aatcctgatt ttagaagacg
    46741 aacgtctgcg tgacttgatg gatatcaaag tatacgtaga tacagatgat gacattcgta
    46801 tcattcgtcg tatcaaacgg gatatggaag aacggggacg cacattggac tccgtgatcg
    46861 aacaatattt gacagttgtt aaaccgatgt atcatcaatt tatcgaacca acgaagcgct
    46921 atgcggatat cattgttcca gaaggcggag aaaaccacgt tgctattgat ttgattacaa
    46981 caaaagtagc tagtttctta aaccataaat agtgcgcagc gaaacagttg aacggactgc
    47041 gaccgtttga aaagcaagga ttctgctttt tgaacagtca ccagccaact gtttttttat
    47101 ttataacaag aggttgtgaa aacagcatct tgacctaagt attaaaaaga agaaacggaa
    47161 aatagctgtt tatattttac cgttttttga gctaataccg aaggtcagct gattgagcac
    47221 cgtgaagtag aggttgtaaa aaagctgtct ttgcatcaag cgataagagc atccaaataa
    47281 aacagctcct cacgtttttc gttgggttgg gcttattatc gtagatgcaa gcttttgaac
    47341 accgtttaac gagaggttgt aacagaagtg gtcagatgca ataaataaga agaaacttac
    47401 gaaaattatt tctcgaattt gtgtgagatt tcgacttatt tttttgaaga agctcttttg
    47461 tcgcaccccc
//
LOCUS       DAZKNV010000017        46702 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000017 DAZKNV010000000
VERSION     DAZKNV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.017"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            188..1069
                     /locus_tag="ACG8M1_001055"
     CDS             188..1069
                     /locus_tag="ACG8M1_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0421782.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            1082..2692
                     /locus_tag="ACG8M1_001056"
     CDS             1082..2692
                     /locus_tag="ACG8M1_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421783.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2769..3428)
                     /locus_tag="ACG8M1_001057"
     CDS             complement(2769..3428)
                     /locus_tag="ACG8M1_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0421784.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3711..4376)
                     /locus_tag="ACG8M1_001058"
     CDS             complement(3711..4376)
                     /locus_tag="ACG8M1_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFQ0421785.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4523..5128)
                     /gene="dhaL"
                     /locus_tag="ACG8M1_001059"
     CDS             complement(4523..5128)
                     /gene="dhaL"
                     /locus_tag="ACG8M1_001059"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFQ0421786.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(5156..6166)
                     /gene="dhaK"
                     /locus_tag="ACG8M1_001060"
     CDS             complement(5156..6166)
                     /gene="dhaK"
                     /locus_tag="ACG8M1_001060"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFQ0421787.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(6141..6536)
                     /gene="dhaM"
                     /locus_tag="ACG8M1_001061"
     CDS             complement(6141..6536)
                     /gene="dhaM"
                     /locus_tag="ACG8M1_001061"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFQ0421788.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6690..7010
                     /locus_tag="ACG8M1_001062"
     CDS             6690..7010
                     /locus_tag="ACG8M1_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFQ0421789.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(7122..7979)
                     /locus_tag="ACG8M1_001063"
     CDS             complement(7122..7979)
                     /locus_tag="ACG8M1_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0421790.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(8087..9391)
                     /locus_tag="ACG8M1_001064"
     CDS             complement(8087..9391)
                     /locus_tag="ACG8M1_001064"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0421791.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(9388..9897)
                     /locus_tag="ACG8M1_001065"
     CDS             complement(9388..9897)
                     /locus_tag="ACG8M1_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421792.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(10072..12207)
                     /locus_tag="ACG8M1_001066"
     CDS             complement(10072..12207)
                     /locus_tag="ACG8M1_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFQ0421793.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12290..13945)
                     /locus_tag="ACG8M1_001067"
     CDS             complement(12290..13945)
                     /locus_tag="ACG8M1_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0421794.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13947..14261)
                     /locus_tag="ACG8M1_001068"
     CDS             complement(13947..14261)
                     /locus_tag="ACG8M1_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0421795.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14431..14691
                     /locus_tag="ACG8M1_001069"
     CDS             14431..14691
                     /locus_tag="ACG8M1_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFQ0421796.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14705..15019
                     /locus_tag="ACG8M1_001070"
     CDS             14705..15019
                     /locus_tag="ACG8M1_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFQ0421797.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15749..16303)
                     /locus_tag="ACG8M1_001071"
     CDS             complement(15749..16303)
                     /locus_tag="ACG8M1_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFQ0421798.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16429..18358)
                     /locus_tag="ACG8M1_001072"
                     /pseudo
     CDS             complement(16429..18358)
                     /locus_tag="ACG8M1_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(18664..19380)
                     /locus_tag="ACG8M1_001073"
     CDS             complement(18664..19380)
                     /locus_tag="ACG8M1_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFQ0421799.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19381..21204)
                     /gene="glpO"
                     /locus_tag="ACG8M1_001074"
     CDS             complement(19381..21204)
                     /gene="glpO"
                     /locus_tag="ACG8M1_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFQ0421800.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21218..22714)
                     /gene="glpK"
                     /locus_tag="ACG8M1_001075"
     CDS             complement(21218..22714)
                     /gene="glpK"
                     /locus_tag="ACG8M1_001075"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFQ0421801.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22850..24310)
                     /locus_tag="ACG8M1_001076"
     CDS             complement(22850..24310)
                     /locus_tag="ACG8M1_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421802.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24300..25595)
                     /locus_tag="ACG8M1_001077"
     CDS             complement(24300..25595)
                     /locus_tag="ACG8M1_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0421803.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25927..26604)
                     /locus_tag="ACG8M1_001078"
     CDS             complement(25927..26604)
                     /locus_tag="ACG8M1_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFQ0421804.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26634..27725)
                     /locus_tag="ACG8M1_001079"
     CDS             complement(26634..27725)
                     /locus_tag="ACG8M1_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFQ0421805.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(27826..28260)
                     /locus_tag="ACG8M1_001080"
     CDS             complement(27826..28260)
                     /locus_tag="ACG8M1_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFQ0421806.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28844..30301)
                     /locus_tag="ACG8M1_001081"
     CDS             complement(28844..30301)
                     /locus_tag="ACG8M1_001081"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0421807.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30298..32193)
                     /locus_tag="ACG8M1_001082"
     CDS             complement(30298..32193)
                     /locus_tag="ACG8M1_001082"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0421808.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32251..34026)
                     /locus_tag="ACG8M1_001083"
     CDS             complement(32251..34026)
                     /locus_tag="ACG8M1_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFQ0421809.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(34076..35572)
                     /locus_tag="ACG8M1_001084"
     CDS             complement(34076..35572)
                     /locus_tag="ACG8M1_001084"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0421810.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35766..37388)
                     /locus_tag="ACG8M1_001085"
     CDS             complement(35766..37388)
                     /locus_tag="ACG8M1_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFQ0421811.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(37716..39029)
                     /locus_tag="ACG8M1_001086"
     CDS             complement(37716..39029)
                     /locus_tag="ACG8M1_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFQ0421812.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(39274..39498)
                     /locus_tag="ACG8M1_001087"
     CDS             complement(39274..39498)
                     /locus_tag="ACG8M1_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421813.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(39518..39940)
                     /locus_tag="ACG8M1_001088"
     CDS             complement(39518..39940)
                     /locus_tag="ACG8M1_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0421814.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(40082..40792)
                     /locus_tag="ACG8M1_001089"
     CDS             complement(40082..40792)
                     /locus_tag="ACG8M1_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFQ0421815.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(40810..41307)
                     /locus_tag="ACG8M1_001090"
     CDS             complement(40810..41307)
                     /locus_tag="ACG8M1_001090"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0421816.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(41344..41796)
                     /locus_tag="ACG8M1_001091"
     CDS             complement(41344..41796)
                     /locus_tag="ACG8M1_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0421817.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(41931..42536)
                     /locus_tag="ACG8M1_001092"
     CDS             complement(41931..42536)
                     /locus_tag="ACG8M1_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFQ0421818.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(42986..43606)
                     /locus_tag="ACG8M1_001093"
     CDS             complement(42986..43606)
                     /locus_tag="ACG8M1_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0421819.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(43608..44477)
                     /locus_tag="ACG8M1_001094"
     CDS             complement(43608..44477)
                     /locus_tag="ACG8M1_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFQ0421820.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(44500..44907)
                     /locus_tag="ACG8M1_001095"
     CDS             complement(44500..44907)
                     /locus_tag="ACG8M1_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFQ0421821.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(44926..46215)
                     /locus_tag="ACG8M1_001096"
     CDS             complement(44926..46215)
                     /locus_tag="ACG8M1_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0421822.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            46273..>46702
                     /locus_tag="ACG8M1_001097"
     CDS             46273..>46702
                     /locus_tag="ACG8M1_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0421823.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT        13178 a         9915 c         8000 g        15609 t
ORIGIN      
        1 tataactatc tattgagaaa gtatcaagct agcaattcct tgtttatgaa ttcattgaca
       61 gaaatttata aaaagaatat tatgtactaa aataataaaa aaagttttat aaaaaggtat
      121 aaaacctttt tattaaacta tttaatcttg tttagtatat atttttagaa aaaggagtgg
      181 ggtttttatg gcagaaatcg tcaaagtcac acatttgaaa aagagctttg gtcgtttcga
      241 agctttaaaa gatgtctctt tcaccgtaca ttcaggtgaa gtcgttggat ttatcggacc
      301 aaatggttct ggaaaatcca cgacgattcg gacactttta gggattataa aaaaagacgg
      361 cggaacggca acgatttttg ggcaagatgt atgggaagat agtttatcta tccatgaacg
      421 tctttcttat gttccaggcg atatctcttt gtggggaaat ttgactggag gagcgatcat
      481 cgatctcttc atgaagcttc atggaaaagg gagtgctcaa aaaaaagatg aactgattca
      541 acgtttctct cttgatccta agaaaaaagc aaaaaactat tcaaaaggaa atcgccaaaa
      601 agtgggcttg attgctgctt tggctgttga ttcggatctc tatttatttg atgagcctac
      661 ttctggttta gatcctttga tggaaacgat tttccaagaa gaagttgaaa aattgaaaga
      721 acagggcaaa tccatcctac tttcttctca tattctcagt gaagtcgagc gactagcgga
      781 taaagtcgtg atcatacgcg aaggaacact cgatgaagaa ggaacactcg atgaattgcg
      841 tcatttgact cgttcgacca tcactataga aacagaagca gagaatagtc acttagcaca
      901 attgaacggt gtccatgact ttgtgcaaaa aggtcacctc gctcaatttg ctgctgataa
      961 cgaagctttc gatgtgattt tagctgaagc gtccaaatta ggtgtgaaaa aatttgaatc
     1021 tattccaccg actcttgagg atttattcat gagacattat gaaggatgag gaggaagcga
     1081 aatgactgat aaattttcac gctggtccac ccttttttct caaaacctta gccgtgactg
     1141 gaaaaagatc ctgatatggc tagtcggtgt cactgctttt tctggtggtt ttgtccctgc
     1201 gtttgaagaa ttgacttccg gacaaggatt agctggatta tacgaaacct tgcaaaaccc
     1261 ggcaatgatt gcaatggtcg gaccaactcc agcttcgaat gctgctgagt atactttagg
     1321 agcgatgtat gcaaatgaaa tgttgctttt ttgcagtttg tttgctgctg tgatctctgt
     1381 tttacacgtg gtgagccaaa cgagaaaaaa agaagaactt ggtctgattg aacttattcg
     1441 ttcctttcga gtcggacgtc aagcaaactc tttagctgtc atcgctgaaa gtattctgat
     1501 caatttgctt ttagcaatat cgatcagctg tacgatgatt tttttccaag cggattcgat
     1561 cactgcagaa ggtgcttggc tttttgggct atctgtaggt agtatgggga ttttggggag
     1621 tgccgttgca ctgtttgctg cacaactgat gccaagttca gccagttcga atggtctgtc
     1681 tttagcgttt ttaggtggac tttaccttct acgagcaata acagatgtag ctgattcctc
     1741 cctttcgatg tggaatcctt taggctggtc ttatttgacc tatccattta caactaacaa
     1801 ctggattcct ttgctttatt tgtttttgtt cagtctaatc ttgataatca gttcatttgt
     1861 tttagaggaa catcgagatt tgaacaccgg ctatatcccc gaacgtgaag gaaaaccgta
     1921 tgctaaacgt tctcttttat ccttgcgtgg tttattattc tatctaaata aagggatgac
     1981 aatcagttgg cttatcactt ttggtttgat gggggcggca tacggctcta tctacgggaa
     2041 tatgcaacag tttttagaaa gtaacgactt aatgaaacag atgtttatcc aatctggcgt
     2101 ctcaattgaa aaaaacttta caagcacgat catggtagtc ttgatttgtc tagctgctat
     2161 tttaccaatt gctagcatca atcgtttatt tacagaagaa acccacggac gtatgaatca
     2221 gctgttcgca acaaaaattt ctaggaacca actttattgg accaatatgt tactagctat
     2281 tctatttgct atattggcaa tcctgattag ttctggtgca ctagggcttt ctgctttggc
     2341 ttcgatgaag gatgcgaaag acatggatct attgatgttt cttaaagccg ggttcaattt
     2401 cctgcctgcc gttttagtgt ttatcggaat tagtggcttt ctattcggat ggcttcctcg
     2461 aatcggtaaa cttgcttata tctacttagc ttactccttt gcactcaatt actttggcgg
     2521 aattttggat ttaccagaat ggttttccaa aacagctgtc cctagctggg ttccacggat
     2581 gccaaacgat tcttttgatc tttccgtgtt ccttacgtta tcatgtatca gccttgcact
     2641 gttcgtcctt ggttctattg gttataggcg aagagactta ctagaaggat aataaaaaag
     2701 catgtacaat ttcatgctag cctccaaatc tgggtcaaaa atccaacatt tggaggtcat
     2761 ttttttattt acaagtcttc taactgctct ttatcaatga tccagacttc tcgattcttt
     2821 ctttttacat aaccattctc ctctaataat ttaaattttc tagataaagt ttcgggggtc
     2881 gtaccgataa atgcagcaag ttctttcatt ttcattggca ggaaaaagtg atccttccct
     2941 gtcgctttag ctaagtcaag cagatagaca gcgactcgtt cttctacttt ttccatcatc
     3001 aaaaaagttg tctgctgctg tacttttgtt aatttctcaa cgttgattgc taaaagtttc
     3061 agactaaggg cgggataatg cagtaagagt tccgagaaat ctttttgtct caatatgcaa
     3121 atttccgttt tttctagtgc ttcgccaaat aaagactcat ttggaacgcc tagcaactgg
     3181 ctctctccct catatccgcc cggctctatt actcgtaaaa gctgttcctt tccgctagca
     3241 gataattgat acactttcat actgccggag gccacgatca ctaattgagg ttctccattc
     3301 ggcgcaagaa tctgttctcc tttttccaca tagtgatgtt tgacaagtgc gtgtactttt
     3361 tcttgatctt gctgtactaa gtgattgaac aaaggaacaa atgaaacaca taaatgatca
     3421 tgactcataa tctctcctcc ttctaaacag ctatttctaa taaagaaaca taacttccct
     3481 tattccaact gataattttc ttttatcata gcataaacgt caagcgaacc agataccagc
     3541 aaatagagtg gatttctttt tgtcccttgc tttattttcc ttcttttgag accttaagta
     3601 attgattcct atcaattttt taaatattta ctttttgaat aatcaaaaac aaaccttcac
     3661 tcgcaagccg agagtaaggt ttgtttttcg cattgcttat ttcgtgttgt ctattgaaat
     3721 ttttccgcac ctagcttttg atatagtggt gctagttctt gtaaggtttc agcggttatt
     3781 tgctcaacgt gttcgatttc ttgcggatag aagaatagtt tacccatttg aaaggttcgg
     3841 tctctcatcg cttttttcaa ctcttcttgt ttctttgtat cggacaaata gtcagacaaa
     3901 gctaagtggt cgtcaagttc atgttctggt tgcggccata tgtaataatc cttgatatcg
     3961 actgttttgc tccactcttt cagtatcgca agcaactggt tatacgctgc aatgctacca
     4021 tatcgttctt cgcttttata atgttggtac atcaaataga tttggtattg tttttgattc
     4081 aacaaaactg ctagacaggc attctcgtct tgacgagatt cgcttcggta cgcgctccaa
     4141 aaatgactgc gtaaattcca gccattcgtc cagctttcga ttttaggttt gctcatgccg
     4201 tacatatcag gcaaaagtgc agctgtctgg agctgaatct ctttccattt ttgccagtgt
     4261 tctttatatt ctttcttgat ttgttcaatc ttatctgttg gatggctctc tttgagctgt
     4321 ttgaatgcgt agattggtcg atcaaacaac tgataatctg attttccaag ttccattgtt
     4381 tcgcctcttt ccgttatctt ttgtattcta cctgaatttt gcgatatgga caaatagagg
     4441 ttgtgaaaaa gctgttctgc atcaagtcat aagaacagcc aaacaaaaaa ctgcgatgag
     4501 catcaccgca gttttattga acttaaggtt gattgatcac atctaaaagc gttgaaaata
     4561 aaatggcact agaagcagct cctgggtcga tatgtccgat tgcacgctct cctagatagg
     4621 aagctcgtcc ttttttagct accaagactt tggtgtgttc ttttgcctgg tcaatgattt
     4681 cttttgttaa attccctgcc ttcaatgcct ctgtgactgg cagccaaaca tctaacatcg
     4741 ttttatcgtc agcttctgcc tttcctcggc tttgaatacc cgctgttccc tgctcgatca
     4801 cttcgcctaa tttttcttga gaatcaatag aatcgacctc ttttgtcgct ttcatcatgt
     4861 tcatgaatgc agatccgtat aacggaccag aagccccacc gactttcgat atcatcgcca
     4921 tagagaatac tttgaatgta tcgctgattg tttcaggatg atcggcttga aaagcttctt
     4981 cataagctga aacccctctt cccatgttat ttccatggtc tccatcgcca atcggggtat
     5041 ctagatcact gagatattgt ttgttctgat tgattgcctc tgcaaattgc gtgagccatt
     5101 cttggatttc ttgaacggtt agtttcatat tatcaccctt ttatcttgag attttttacc
     5161 atgaaatcgt ctgtacattg ctttctaaag aatctttcca ttgtgtctcc gtcaagtcga
     5221 tcagtgttag agaaagacct tgcatatcta gtgaggtcat aaaattaccg acttttcgga
     5281 aaactacatt gacgcctctt tcttccaaca gagctaaaac atcattcatg aacacgaact
     5341 gttccatcaa aggcgtcccg cccattccgt tgactagtac acctgcttct tttggtaaat
     5401 tcgagtaatc atctaaaatc ttagtaacaa gttcctttgc cagtacttta gaaggctgca
     5461 tcttttctcg acgatagcct ggctcaccgt ggataccaac accatactcg atctcatctt
     5521 ctcctagttc gaatcctggt ttccctactt ctggtacagt tgctgctcga agcgctagac
     5581 cgatcgtctt agttgcctgt acgacctttt ctcccagttc tttcaactca gctagggaag
     5641 caccgtttct tgctgcatcg cccacgattt tgtgtacaag gacagtacct gcaactccgc
     5701 gttttccagc agtatacgta ctattttcaa cggcgatatc atcatctacg atcacacttt
     5761 ctacttcaat atcgtccata gcagctaatt cctttgccat atcgaagttc aatgcatccc
     5821 ctgtataatt cttaacgatc agcaaaactc cttttccact atcggcttcc ttaatagccg
     5881 tctgaatctg atctggagtt ggagaagtaa acacatcacc aagcaccgct gcacttaaca
     5941 tcccttcccc tacaaacccg gcatgggatg gttcatgtcc gcttcctcca ccagaaacca
     6001 aaccaacttg ttccgctttc tgattcttgg ctacaacacg ggaagattct acacgatgaa
     6061 caagttctgg atagcttttt actaatcctt ccagcatttc ttcgacaata ttgcttggat
     6121 cattcatgat ttttttcaat ttattcccat cctttctttc cggcattttg tgcttctgtt
     6181 aagatttgct gagtatcatc tgttataccg gcagtgatgg ctgctgcaaa agctccttcc
     6241 actaaaggcg catccaccag atgataacgt tgctgctgct cttcttccaa catgtctttt
     6301 gccagttccg agttcaatac cgcgctaccg atatccgcaa aaacaaaata actagctgca
     6361 tcgcttgatt cattgactgc ttctacgatt ttcatcgggt ctgatccgat ctcgccattt
     6421 attccgccga gagaaaaaat ttgcacctct tcggattttt gcatctgctc aatcatttct
     6481 ttaataccat ctgttacttt ttgactatga gaaataagca aaatactttt tttcacaaga
     6541 atcttccttt cttttacata gttgctaacg attggtttcg ctttcattaa tgaacaattc
     6601 aagtatataa taaatttcta attttgggaa aatatgtgta gtgcttcttg aagtttgtta
     6661 tactttaatt aaaagagagg agtgatcgaa tgattacaac aacaacgaac agtgtagagg
     6721 gaaaagccgt agtagcttat aaagggatcg tttttggtga ggtcattact gggatccatg
     6781 catttaaaga cttggaggcg gggttgcgaa atatctttgg cggccgctca aaaagctatg
     6841 aaaacgaact aatgggtgca agagaagaag cacttgccga aatggccgaa cgtgcaaaag
     6901 cattaggagc tgatgcgatc attggcgtaa aaatggacta tgaagtatta ggcagcgaca
     6961 atggcatgct gatggtcaca tgtagtggaa cagctgtctc cacgagataa gtaggggaca
     7021 tctgttttaa taactaaaga gagatgggac atgtagtggc actcaagaat tagatttttc
     7081 agtctaactt cgaggtactc taccttccca tcctctcttt tttatttctt tttgcggatg
     7141 attccgtaag ctgctgcgac taacacaccc gcccctgcta aggaataact gacagaagct
     7201 gttttttcat ttgtttttgg caaagtctga cttgttgatt tggatggctc tgtcgtttgc
     7261 tgaactgttt ctgtcgtgct tccagaggtc actgattttt ctcctgccga atgcaaaata
     7321 tcttttattc gttggaaact agctgctaag tcagcttttt ttgcttcaaa atcattagca
     7381 actgtttgtg cttcgctgat ctttccgtgg attgcttgac tggccgctgt gatatccgct
     7441 tgagtttgac ttagctttcc agaagctgtt tgagcaacct gatttaattg ctgattgaat
     7501 tcttttgctt gttggatctt cccgtcaaga tctgtttgga cagcttccgc ttttgctttc
     7561 gcttcggcaa gctttttctc aagttgtgca cggtcatttc ccactttatt tttaagatca
     7621 gctaaatctt gatcgattgc tgcttggtct tctttcaatt tgttttttgc agcttctaat
     7681 gcttcttcga gttcttttct tttattttcc aagtcttgca aatgatcgat ttggtcagaa
     7741 gaggtagaac tatttattga tgtatcttct gaagatgaaa tcgtttctcc tgaattatct
     7801 gtcggtacat tggaagtcat ttctgtttcc gaggcaccgt tttcagcacc agaagagctt
     7861 atggttgttg aaggttctgt ttgagcaggt tcagaagttt ccgcaaaagc tgtctgtccc
     7921 aataagaaaa tactggaaac agcaattggc cagattaacg gcttcattct ttttttcatc
     7981 acttttccca tccttactac tttttaacta atttcttatt ataagcaaaa atgtttggaa
     8041 gaaccataaa cacaacaggc tgtttgtcta aaaaacggtg catcttttat ttttttgtac
     8101 gttccgggct tttccatgtc ccgcttccat aacctaaaat cgttttgact gctggaatga
     8161 aagtcgtcac gatcgttatc gcgttcacta tccagaacaa aagcatatat agtggtgcga
     8221 aaagaaggta tttcaatttt cttcgtcgat catctacaat cagcgaagct agcaactgga
     8281 aaaatcctgc gaccatttca aagcagatga acacaaaact gaatgtaaaa gtaatataaa
     8341 tctgttcgta gtttccttga tatacataat gcccgattaa tccagcaaaa agaactacgg
     8401 aaatacaaaa gaatattgac cagacaatac tcaatgtttg atcaatgaag atgatcgttc
     8461 ttccaatatg tttaaaagga tggagcatca cttttttgaa attcgtcagc cagacttctg
     8521 ttccaccttt tgcccaacgt tttctgtgtc gatatagcat cttcaacgtc acaggtactt
     8581 ccatgaaaaa gataatctca ggagcaaaaa cagataacca gtcatttaac tgatgatccc
     8641 aagcaatact gatgtcttct gtcgctcgat cttgtctgaa tccgcccaca tcgatcaagg
     8701 cttcttttcg atacatcgta tttgctccac tgtacgcata aagaccaccg aaaacagctg
     8761 actgtgttcg tttaatgatg cccacgatac ttgagaattc aaccgtttga gattttgcaa
     8821 tcaatttggt acgattttgg acatccatat ttgcagtgac cgcagcaata tgtcttgcac
     8881 cagggcgaat gaaataattc acatacctaa tcagtgcatc tggctccggt accgtgtctg
     8941 catcattgct taaaatcaat ttcccttttg caaaggcaag tccgatatta aacgcgtggg
     9001 cttttccttt atttttttcg atccgaacca cacgaagatt agcgtatttt ttcatcagtc
     9061 tagctaatat ttctggtgtt tggtccgttg aaccatcgtc tgtcactaat acctcatagt
     9121 tgtgataatt caatttcgtc atcaaatact cgattgtata ttcgatcaca atttcttcat
     9181 tatgggctgg caccatgatc gtgatgaacg gttcgacact caagggaaca tctacccatt
     9241 ctttttgctt atgtttgtat aaaaacacat aacaccagac accaataaac catacaaatc
     9301 cgcctaaaat cggataagaa acgagaaaaa aatacataat agacaaacaa gtatctaaga
     9361 ataaattacc tgtatgggtg attgagatca tttcagttcc accccatttt ctttatacaa
     9421 atctgcaatg aatgtcgtat ctagattttt ctcttcggag acagaataaa aacggaccgt
     9481 ttctctctct tcttttgttc caaaacgttc cgtatacact tcttcaagta attcttgtct
     9541 ttttttcaat ttttcatctt catattcaaa agatttattt acttttttgt atagatttcg
     9601 attgttccac ctagtcaata caaatgaggt aatcaggaaa ctgaaaaaaa tcaatacaaa
     9661 aaagccgatt aagaaataca gcattttctt ttctgataaa aaagcgtaca aggaaaaatc
     9721 cttggctctt tctggtctcg ttaatgggaa aaagacccat ataaaaggaa gaacaacgat
     9781 catccatcct aaaagagcca ctaacgtttg ccaaatcttt aaccagtaat taccttttga
     9841 aaaatactta tctttcacca aaattgatgc aacttcttct cttgttactt ttttcatatc
     9901 ctcacctcac gtttttttgt tacgacgtag gagtttacca tacatttcat ttcttttcac
     9961 ataaagtgtt cctaaatttt tcctaagaaa aagaacaaaa catttctcat cagcaaatga
    10021 aaaatatttt gttcttttta tcagttgttc tttttatttt ttatctctta attatgttgc
    10081 tctttccaat acgacaatgc ttttcattcc tctagatatc gccgtgtaca tttgtctgcg
    10141 tcttctttgc tcatctccat cgttttcaaa tggatataag attacatgat caaattccag
    10201 tccttttgct agactcaaag gaatgatttg gcagttttct aatccatatg aatttttttt
    10261 aatcgattct tgtagcgttt gggtttcctc ttctgtttgg gtgataactg ccgctttttc
    10321 tccttttaga gaaaccaaaa tctcagctag tattttcaac aattcttcag aggatcgaaa
    10381 agagcggtat tcgggttctt ttccttgcgg tcggatcgat acgatgtcga tcttctcttg
    10441 atccacagca taggttttga aaagctctgt gattgctccg ctagaacggt aactatttct
    10501 aagatcatac cgatggatcg gcagatggta gtcgtcgaaa caacgcataa tatcagcaaa
    10561 agtagtggaa gaattaaaga ttgcctgatt ctcgtcacct actaaagtaa agtgagtttt
    10621 tggaaataat tcgatcaata gacctaattg tgccagggta taatcttgta cttcatcaat
    10681 caatagatag cgaaatgctg gtacatttac cttttcaaca agtaaatgac gaatagctaa
    10741 tataatgact gcttcatcaa cagtacgtgt gggttgccaa gcataagctg agccatatcg
    10801 tttttcataa attctttcaa acaactgatg ctcatccacc catgccattt cttcgatttg
    10861 tctggttatt tttcgatatt ttttttgtaa aagtttcctt gcataagcta caatactttg
    10921 ttccgaatca tcagaaatca atttaccgaa taattccaac tgcctatctt ctgtcaacga
    10981 gagtacctga ttctgcacag caggactttt tgcttgtttc aaaagatgat tcttccattc
    11041 gctcatcagt gcctttttcg ttgcttgaag cctatcgatc aatttaggat gagcaggaac
    11101 tttctcatat attttttcga tcgttttttt agaaaggact gtttttccat ttttagtaag
    11161 tccacggata aaattcggat gatctaaaaa caaaggatct gattgtttta gattatcgat
    11221 aaactttttg ctacgcaaac gttctgtctg ctccgataca ttttctcccg tgatacgttt
    11281 gaaataagcc tcttcacctt ctatttcctc tgctgaaagc tgtgaaacca gctgtatgat
    11341 ggttagattc agtggatttc tttcacctaa tgatggtagg acattcgaaa tatagtcgat
    11401 aaaccgatga ttaggtgata gaatcagcaa gtcatcggat gtcatcgtat ctcgatataa
    11461 atagagcaga tacgcaatac gctgcatgat agcagaggtt ttaccacttc ctgctacgcc
    11521 atttaccaag atattttgac ttttcacatc ccgaatgatt gtgttttgtt ccgattggat
    11581 cgtagcagtg atagccttca tttcattggt ctcatcttgg cctaagactt ctaataatac
    11641 gtcatcttga atagctacag acgtatcaaa aaacttgacc aaacgatctc tttccaaaag
    11701 aaattgtcgt ctttctttaa taaccgtatc gattttattt tgacgaaccg tataagaaga
    11761 tggaccaatc atgttattgt aaaaaagttc ggcaattggt gaacgccaat cataaacaag
    11821 attttcatct gcatcatctg tgaaatttgc tgtaccgata taaaaggatt cttttggctc
    11881 attatccaga aagtctacaa cgacttttcc aaagtaggga cttttcaata aacgttcgat
    11941 ctttgctagc tgattttctg cgtttttctg tttgatattc atctgatcga tttctctatt
    12001 tttcatttca atcatcgaaa aagtatccag gttatctaag taactgtcaa aattcaatcg
    12061 aagctcgcca gccatttctt tcaacgactg gtttccttct atttttgccg tatccatcga
    12121 ttcccgcagt tcgttttttt tatcaattag cttttgatac acgttcttca gatatgcttc
    12181 ttctaactgt ttttgtgtgt tgaccataca cattctcctc tttttttaaa gtggtggaac
    12241 cgattagttt acctctttta agagtcgaat gcaagctttt taacgagtat catttgttag
    12301 gatatatcag ttcttcaggt cggacagttt gatataaaga aaatgcacca tcaaggtttt
    12361 ttacgtggta gccagactgc ttcaagattc tttccgctag atagctacgt aatccgctat
    12421 gacagctgac gatatattct tgttggctgt ctaattcatt taatcggtcc cgaagttcat
    12481 tcaaagggat atgtttggct tccttgaatt tgcccttttc caattcttct gctgttcgca
    12541 catctaataa aatttttcct tttgctagtt ctgtcggcaa ttcatgccat tgtacggttt
    12601 cactaagccc ttctgcaatg ttcattgctg catatcctag catgtttact ggatctttgg
    12661 ctgagccaaa tggcggtgca tacgtcaatt ctaattccgg taaatcgaag atcgtcaaat
    12721 gccctttgat tgctgttgct aaaatatcga tccgtttatc cacacctttt gccccaacac
    12781 cttgtgcacc ataaatctcg ccagtctctg gatggaagat caacttcagt aaaatatctg
    12841 ttgcttctgg ataatagctt gcatgatctt ttcctgatac atgaatgact tcaaaagaca
    12901 gttcgttttc tttggctgtt ctttcactta aaccggtgga tgcggcagtc attccaaacg
    12961 ttcgtataat tgctgttcca ataccgcctt gatttcttcg agaaattccg gaaatcgtgt
    13021 ccgcaacttg tctaccttga cgattggctg gtgaagcaag agaaataagt gcatcttttc
    13081 cagtgatttg ctgttttaca acgatagcat cccccaccgc ataaatatca ggaatattcg
    13141 tttgataacg ttcgtctact aggatacccc cgcgtatgcc taattcgatt ccagcggtca
    13201 ctgctagctg gttatcagga cgaacaccaa tggataaaat aactaaatca gcagggatgg
    13261 tacgcccatc atccagtcgc aatcgtttcc cgtggtcttc aaatccagcg acagcatgag
    13321 aagtaatcac ttctactcct tgatgagaca attctttttc tataaaagct gccatttctt
    13381 catccagtgt tggaagaata tgtggtgctt gttcgatcac catgacttct aaacctcttc
    13441 tttttaggtt ttctgccatt tccaatccga tgaatcctgc accaacgatc acggcacgct
    13501 ttggctgttt ttctaatgca tgcatcactt tatcgatatc tggtacattt ctaatagaaa
    13561 aaacattgtc ggcttctgtt atccctggaa tcgatggaac aactggtttt gcaccaggag
    13621 ataaaaccaa tgcatcgtac tgttcaatgt gtttttgacc ctcatgtacg acttctaccg
    13681 ttttgttttc gggaaagatg gctgtcactt catgatttgg acgcacatct aaacaaaaac
    13741 gagcggataa tgattctggc gtttggacaa gaagattttc ccgttcactg atttctcccg
    13801 aaagataata aggcaagccg caatttgcaa aagaaacata cggtcctttt tcaaaaacaa
    13861 cgatttctgc atcttccatt aatcggcgaa gccgtgtagc agcagacatt ccacctgcta
    13921 cacctccgac aataacgatt ttcatcttat ttccctccta ctgttcgatc aaaccattga
    13981 ttcatgccac cacgtacatt cactacatca taaccagatt tctttaattc tttagctgct
    14041 tgtttactcc tcatccctga ttgacaaatc acatagacgg tcttttcttt gtctccatca
    14101 tatctgttta tactttgtaa tggaacattt ttagctcctt ttatatgccc gccccggtat
    14161 tctgcaggtg ttctaacatc aagtaacgct ggattttcca aaagcttttc ctttaattct
    14221 gggactgtta tcgattttat tgattgaaat agcaaattca ttttctgcac ctcatttaca
    14281 tttttataaa tacctcatgg ggtatattaa acaggagctt tattaatatg tcaaccagaa
    14341 tgactcttca tttttttcac tactttttat atttgcataa aataccgata aggggtatta
    14401 tctaattata aaaatagagg agaatgtgtt atggagattg ataataaaaa tatcctgaac
    14461 cgtttgaaac gtacagaggg acaaattcgt ggtatccaaa aaatgatcga agacgaaaaa
    14521 gaatgtatgg atgtcatcac tcaattaagc gctgttcgtt ctagtattga tcgcgtaatg
    14581 ggcatgatcg ttgcagataa tctgaaaaat tgctttgaga aacctgatag taatccagaa
    14641 gaacaagcgg ctaaactaga acaagcgatc aagatgatta ttaaaaagta aaggaatgat
    14701 ttcaatgaaa gtcgttttcc atattgatga attagaaaaa tggtcagaaa cagggaaaaa
    14761 cgtaaaaaac ctgataaaag cttctccaga aacgacgatt gtcgtatctg taaatggcat
    14821 cgcgattacc ggttatctag actctgccaa tgcagaattc ttagatttgc aaggagtcgt
    14881 ttttcacgct tgcgccaatg ctatgcgtgc taatcatatt tcagaaagtt ctttacctga
    14941 acaagtaatc gttgtaccag caggtgtcct tgatttagtt gaactgcaat cccaaggtta
    15001 tgcttatatc aagccttagt cagtagaggt tgcgacagaa gtgatcagct tcaagaaatt
    15061 tcggcttatt tttcgaagaa gctacttctg gaaaaccgtg aatcaaaggt tgtgaaaacg
    15121 ctgtcctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcgttt
    15181 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa
    15241 atcagcggtt tgacctaagt attagagaaa aaaacgggaa aatagctcct catattttgc
    15301 cgttttttga gctaataccg aaggtcagct gattgaacac cgtttaagga agagattgtg
    15361 aaaaagtcgc ttagtttcga gtattaagaa aaattttgtg aaaatggatt tctacatttt
    15421 tgcataaatt tggcttaata ccgagaaact ggcttttgaa taccgtttaa ggaagaggtt
    15481 gtaaaatcag cggtttgacc tgagtattag agaaacaaac ggaaaaatag ctgctcatat
    15541 tttgccgttt tttgagctaa taccgaaggt cagctgattg aacaccgttt accaagaggt
    15601 tgtgagccta ccatttaact ccgaatcaca agaaataatt tcaaaaacaa cttctcctgt
    15661 ttttggttcg gttggcttat tatcgagaag tagctactgg gagtctattt atcaaaaaaa
    15721 ggaatgcgac ataggtcaca cccctttttt attttctttg aaacatcttt cggtactcga
    15781 cagcatacaa gacaaaagat tgtaaaagac cgtaagtgat gacggcaaaa atgactctca
    15841 cccacagcgt tggtaattct gggaaaagca gcaaaaggat catgccaaca tagatgacag
    15901 cagtcgctac tttgccatac cacttcgctc cacttaattt gatattttta gatagcccga
    15961 ttaatccagc tacaaacata aagccttctt ttatcaagaa tagaccaaac aacagccaaa
    16021 gccacggtcg ataccatgcc atagacaaaa tcagaaaaag ttgtgtcaat ttatctgcaa
    16081 acggatcaag caccttccct aagtctgtta cctgattata tctccgagca atgaccccgt
    16141 ctagataatc agacaaacct gagacaacaa tgaccgctcc tgctatataa aatgactgtc
    16201 tcagcacaaa ataaagataa atcggcagca aaaaaatacg gaatatcgat aaaagattcg
    16261 gaatcgtttg tatttcttta cgccagtctg tgcttaattt cattttatcg ccctacctcc
    16321 tcagcactct tttcttttta ttttagctta cacggggaat aaaaccaatg atttcactgt
    16381 ttttattttt ctttacagac actgatatta tgagctaatt tgagataatc acttgctgtt
    16441 ttcatcgttt actcttcttt cttcctgtcg tttgcgcatt tcttttacta gtactttatg
    16501 agcttttttt gatcctcgct ctaggtcacg ctgccgttta cgtgttttat aatcgataaa
    16561 cagactgtct aaatcgtaac ctgtcgggta cagatcttct gctgaacgca ccagacgaac
    16621 acgctgacga ggcacgtgga ttattttttt gtctaaatat acatcaatcg tatcttcacc
    16681 tatatcttca taaactaacg cttctttttg gtattcattg acaaatatcc gatcaccttt
    16741 tgcaaagagc tgacgttctt ttttattctc cttcctattt gtaactgctg tcttaggaag
    16801 aaattctttt ttctgtgtcc gataggcttt ttccgccaag taacgctctg cttgatggat
    16861 caatttcatc gacatatcca ttttatgagc aatccacaaa gcttggcttt ctcctgtttc
    16921 ttccaacccg caactgatat ttaggacgaa gtgcttcccg atcgaaagcc atagcagccg
    16981 gcacaaaatc ttcatgatct ccggcgaatt tcttgatttc tccataatgg gtcgtggcaa
    17041 tgatcaatgc cccttgctca tacatagatt ccatgattgc gatcgctagt gcagcccctt
    17101 catttggctc tgttccactg ccaatctcat ctaaaagtac caacgtattc ctttttatct
    17161 ttttcaaaat agcagcgatg ttttgcatat gaccagaaaa tgtactcaac gcattttcta
    17221 aattttggtg gtcaccgaca tcgacgaaaa tctcatcaaa gacagcaagc tctgtccctt
    17281 cttttgccgg aacttgcata ccgaacatcg ccatcaaagt caataaaccg actgtcttca
    17341 acacgactgt tttgcctccg gcatttgctc cggtgataat caagcctcga tagtctttac
    17401 cgatttcaac atccaatggt accgcatgct caggtaaaaa tggatgtctg ccttgcttga
    17461 taatgatatg ttccgattta ttgattctag gtgtgcttcc attgatttct cggctaaatt
    17521 ttgcccgagc aaagatgata tctaacaccg tgatcgtttc gatcaataaa tcgatcactt
    17581 cttcgttttc tgcgatagca ccagtcaatg ccgccaggac ttgatattct tcactgattt
    17641 cttcagcttt taacaactga tagtgttcat tcaatttaga aatcacagtt ggttcaataa
    17701 aaaccgtcgt tcttttattt gattcatcga taatcgttcc atctatttta tttttatagc
    17761 tggctttgat aggaatcgta tagtattcgc ctttttgaac aatcattgct tcttggatca
    17821 tttctttgtt tttcggatga cgcaagaatt tcagtaattt tgactggatt tctttttcga
    17881 ttagttgtaa ttgtttgcgt actttacgca aattacgtga cgcgtcgtca ctgactttat
    17941 tattttttat tttctggtca atcaactctt ctacatttat caaatcagga agatgtttgc
    18001 tataagcaaa caacaagggt gtctggtatt gattcttatc aaaaaacttt gtgatcatcc
    18061 gactgcttct aagaaaatcc gcatattcga tcaaatcggt tggctgcaga atcaaccctt
    18121 ttttgacttg ttctgtcagt gcatcgatcc tcggcaaccc cataaatgga acatgctgac
    18181 tgctttctaa gatcaagcgt gcttctcttg tttcttcttg acgatccaag acagtttgta
    18241 ggtttgtcga gaccgtcata tcgctgattc gttttttgct atagtttcca attgctcttg
    18301 cttggatttc ctttttgatc cgatcaaatt gtaattgact aatcatttcg ttgtccatat
    18361 tctctccttt tcttgaagag atacctgtcc caaaataaat aagggcctag agataaataa
    18421 aaggatagaa cacagcttaa aaaagtcatg tcctatcctt attagaatac aaagatattg
    18481 ttttcctgac aggtaccgtt tcataagcac accaaataaa ctttgtttat tggctattcg
    18541 acttactgat tagataccag ctacactcac aaaacatacc ccattcttct aggtcttatt
    18601 tattttccac ttaactatag caagacacat tttggttgtc aaactttagt atgttttata
    18661 gatttacacc attaatgaat agacacctac cgcgataatt gctccgatca ttggacctgc
    18721 gattggtacc catgaatatg cccaatctga agttccttta ttagctattg gcaataccgc
    18781 atgtgctaat cgaggaccaa agtcccgagc agggttgatt gcatatcctg ttggccctcc
    18841 taatgaaaga ccgatggcta agatcaatcc acctacagcg aatacgttcg ttccaggtgc
    18901 aaattcgttt tgtccaaaag ctagcaaccc aagaactaat acaaatgtac caattaattc
    18961 tgtgatcaca tttgctggat aattccgtat agcaggacct gttgcaaacg ttcctaaaat
    19021 cgcgctttca tctttcgttg cattccaatg tggcaaataa gaaagccaaa caagaatggc
    19081 ccctgcaaaa gctcctaaaa cttgcgcaat gatgaaagga acgacaagat tccaactaat
    19141 tgcccctgtc atcgccatag ctagagagac tgcaggattc aaatgagctg ggcccatgaa
    19201 tccagaaata tagacagcca ttgttacagc gagtccccaa ccaaatgcga tgacaatcca
    19261 gccagaagcc tgtgctttac ttttgtttaa attcacagcc gcacacacac catctccaag
    19321 caaaactagg atcagtgtcc caataaactc ccccatgatt tgagtcatat cactgttcat
    19381 ttatttctcc ccctttagtt cccgcagatc tgattctgca atcaatgctt ctaaacgttt
    19441 agtctgttgc gccttctcct cttctgtcca ttcaaaatat ccagcaattg catcgatcac
    19501 aggttgcttg atctcatcaa gctgatctcg ttcaaacaac agatgatttg tacgacgaat
    19561 gagataatcg cctggggcca aaaccatttc ttcttctaaa ccataacgta accgagctga
    19621 ctcagcgaga ctcaaaccag gataaggtgc catttctttt gctaattcaa agatacgtcg
    19681 ggcattagtc ccgtaaaaat cagcgatata agtagcatct tcttcctcta aaccggctgc
    19741 tactccttct tttgctaatt ctgtcactgt ttcttctaat ttagttggat cgaagtttcc
    19801 acctgaaatc tgatattttt tagagtcgat ttctttcgtc tctattccgt attcttcttt
    19861 taataattgg cgtatcaatc gcaaagctcc ttctgccatc ttacggtaat cggtgatttt
    19921 cccaccagat aaagtcagca aaccatctgg ttctctttct aaagaactac ctctggaaat
    19981 cgtagaaggt gctttttcat cacggctgtt ttccaaatgg ttcaacacgt cttctacttc
    20041 agcacgagaa actttgtttt ccttatattc acttactgta tcgacaactt tattgaagct
    20101 cttgtctgaa atcgatccat tatctccacc attgtaatca gaaccagaat taccaatcaa
    20161 cagtggacga agtcctgccc agcttgcttc gatatcattc aatgtgatat ttgcttctgg
    20221 atagcgatga ttgatcacat ccaatagata atctacatct tcttgtgtga ctttcggatc
    20281 cgtaaaatct ccttggtaat ccgtatctgt cgtaccaaag taagtcttgt tttctcttgg
    20341 aatagcaaaa accatccgcc catcttgctt tcctgtatcg aagtatgtgg gttgcggtac
    20401 aggcagtttt ttcgcatcta caactaaatg gatcccttta gttggacgca ttttaggaga
    20461 gactggacgc gtaaaattca agtttcgtac tttatctacc caaggaccac tcgtattgat
    20521 cactaatttt gctttgattt cgatcacttc atctgtcagc aggtcacgag ctttgacgcc
    20581 aacgatttga tcgccatcat ataaaaagcc aaccgctttc attttactta ctagataagc
    20641 cccatcttcg gcagcctttt tgatattatc aatcactaaa cgggcatcat tgttgcggaa
    20701 atctagatag acacccgcgc cttttagccc ttcttttttc aaaaacggtt ctctttccaa
    20761 tacttcttct ggtgtcagcg tataattctc atatttggtt cctgtcacat ttgccagttt
    20821 gtcataaagg tccattgcta ctttgaccga gaacatattg aaggttgttg ctccttcgcc
    20881 ctcatagatt ggcaaaagca ttggatctgg ttttgggatg tgtggggcaa tactttgtac
    20941 gactgcacgt tcaccaactg tgtcagctac tacttccaca tcaaatgtct tcagataacg
    21001 aataccgcca tgaacaagtt tggtcgagcg agaggaagtc ccttctgcaa aatcctgcat
    21061 ttcgatcaat cctgttttga ttcctgatgc tgctgactgg actgccacac cggcaccagt
    21121 gattccgcca ccgatgatca acagatccaa ttcttcttgc tgcatttttt gaatgctatc
    21181 ttgtcttgtc ttgtttgaaa acatatggat ttcctcctta ttcaaatgct tgggtagctt
    21241 ttactgcttt tttccaaccg ttgtaaagtt tttctcggcg ctcttcctcc atttgaactt
    21301 caaatagctt gccagcttca taaaattcgc ggatctcgtc tgtatctttc caataaccga
    21361 cagctaatcc tgctaaaaat gctgccccta gcgccgttgt ttccaagttt tctgctcgtt
    21421 ggatcggtac attcaagata tctgtttgga attgcatcag atattcattg tttgctgcac
    21481 cgccatctac tttcaataca ggaatcttga ttccagtgtc atcttgcatc gtatcgatga
    21541 tatctctcac ttgataagca atcgactgta aagtagcttt aatgatatct tcttttgtcg
    21601 taccacgtgt caagccaaac atagcccctc gtgctgcctg atcccaataa ggagcaccta
    21661 gcccaacgaa tgcaggaaca acataaacct catcttcgct tgtagagcgt ttcgctgcgt
    21721 cttctgaatc gctagctttt tgcaacattt gaagtccatc tctcagccat tgaatcgaag
    21781 aaccagccac aaaaatactt ccttctaaag catagtaaac ctttccattt atgccgtaac
    21841 caattgtcgt caataaatta tttttggata attgcggttt ttcaccggta ttcatgacaa
    21901 taaatgaacc tgtaccataa gtattcttga ccatgcctgg ttcgaatgcc atttgtccga
    21961 ataatgcggc ttgctggtct cctgccatcc ctgaaattgg tgcttcgctt ccataaaaat
    22021 gataaccttg cgtataacca taaacttctg agttagaagt gacttttggt aacatcactc
    22081 gaggaatatt tagtaaatct aaaatctcct gatcccaatc tagctgatgg atattgaaca
    22141 acatcgtccg actggcattc gagtaatcag taacatgtgc ttgtccatcg gtcagtttcc
    22201 atactaacca agaatcgatc gttccaaaca tcaattcgcc tttttcagct cgttcttgcg
    22261 cgccttctac atgatcaaga atccagcgta tcttcgttgc tgagaaatag gcatcgatca
    22321 ctaaccctgt tttttcgtgg aaaaattctt gatagccttc attttttaag ttatctgcaa
    22381 ttccagctga ctgtctggat tgccaaacaa ctgcatgata gattggacgt cctgtatctt
    22441 tttcccatat tactgttgtt tcacgctggt tcgttatgcc aatcccagca atctgatttg
    22501 gtttgatccc tgattcgatg aacgctccgg caataactga ctgtacagaa ttccagattt
    22561 catttgcatc atgttccacc caactttctt gcgggaaata ttgcgtgaac tctttttgag
    22621 aactgccgat gtgtcttcct ttcttgtcaa agataattgc tcgtgagcta gttgtacctt
    22681 ggtcaatcgc catgatatac gttgattctg tcattgtgat tccctccatt atatgcaaac
    22741 gctttcttta actactctta tcatactact gttttaaaaa aagaaactgt caaaatttta
    22801 ttcttttttt ctttttttga cagtttttta ttatgaagct attttttaat caattctttt
    22861 cttttttcag cgtctctatt cttcttttca atcgaataat gtcgtaaggt gacgcaaatt
    22921 ctgacagata atattcacac tgttttttgt ttctctggca aaatgtgatc accaaatcat
    22981 attctttacc ttcttcataa cttccaatct caataccgcc gattcccctc agttctctga
    23041 tcagatattg ttgaaaagca atacgataaa tcggcagact ttctaaatcg attccaatca
    23101 ctactggttt tgcaatataa aaatcgatca tcaaaagaac attggcatac tggatcatca
    23161 ggtaactaag ctcactatct tcagctcttt tcctcggcaa ttgctgcacc gctgtttcct
    23221 gtaatttcgc cagtaactgt gttaaggaat gcccgagcat tttctgctgc tgttccaaaa
    23281 gccgatcacg ctcatagact tcgatctttc caacaaagaa aaaccattca ttgttgatct
    23341 gggaaatttg gtagcctact gccttttctt ctttgatttt caaacgacga ggacgataat
    23401 gccataacat cgtttcccga atgtaagtat ctaaaacagc ggttggtaac tttttgctcc
    23461 gtgtcaaatc atactgataa aatatttctt cgtctactat cgaaaaagaa acaaaaaagc
    23521 tgtaaaacat cattgtttcg tatacattca gttctgctgc tgttcgacta agatgcatca
    23581 cgatgattgg atcgattgct tgataaagcc ggtccgactg atagagtaat ttcttttctt
    23641 tcaaagttgc gtacgtactt ttttcattca atagtctttt tttcgtaatc ccgagccagc
    23701 aagcaatctg tgcttctgct gatgccgtaa acgttgtttc taatacacgg tccaatccta
    23761 gaatgaacgg tcttttttct ggtgtatttt gcaaaaaaag cggtcgctga tcttccggga
    23821 tatattggaa tagttcataa taaaaatatc gtatctgtag ctcttctccg tataattgac
    23881 cgtttttgat ttgtaatcca aattcctcta agagctggtt caattctttg atctttcgaa
    23941 aaacagaaga ctcactgata ttaaacgctg tcgctaatcg aacgatggat acttgctgat
    24001 gttctaataa atagacgagc atcttaaact tcaagctttc ctgcaataaa aacaatagaa
    24061 ttttttccaa acttacatct tcgtccaaca caagcagcgc ctgatactca tttcgctgta
    24121 cttctacttt tttttccatc attcggccaa tcaattcaat atcttccaaa tattgatcaa
    24181 acgaggcttt tgacagttgg acatgctctc tcaaaccatt gatagaggct gttccccctt
    24241 gcagaacaag gtttcgcaaa atcaggatct gtaactgctc ttttctttct aataatgctt
    24301 caatcttcat aggcagtatt cgccaccttt gaccacacca tatctggcac acggtattct
    24361 ggctggaaaa atagctcatg ttcttctaac tgttcaaacg tccatccttc ttctactgca
    24421 attgtcagtt ggtcaagaag gtggaacatc tcttttttgc tttggagctg tgctccaaga
    24481 atcttttttt cagaatcaaa tagaaatttg agtttaactt tgctttgatt tattgctgta
    24541 agcttgtagt ctacgtatcc tgtttcaatt ttttggggat aaaaaatgct ctcttcttct
    24601 gtcaaaccta cgcttcctaa gaaatagcca aaccactgat tgccgactgg acgataggtt
    24661 ccctgatcct ttgtctgtga gccactaatt gtcttgctga catttcgtgc tgtacggaca
    24721 gcgttattta ctagagaaac atacattttt tcatttgttg gacgaaaagt tacttggatc
    24781 gcatcgccaa tcgcataaac gtctttttga gacgtttgca agtagtcatc tacccagatc
    24841 gttccatcat cattcaatgt taattgttct tcccacatct gattgtcggg acgagaatga
    24901 ttagccagca aaacaagatc atagttctcc tttctttttt ccgtctctac aatagcggtt
    24961 tcattttcgg tcaaagacac aacttgttct tctaaaaaaa gtgaaagccc ttgatttttc
    25021 atttccttta ctaacggttc tgtcatttca ggatctagat aacgaaaaag aattgacttt
    25081 cggctttcgt aaagatggat ttgttttttt cttgatgcca acccttcagc tatttcgatt
    25141 cctgcttgtc ctgcaccaat aattgcaatt ttctttgcat tcatgatctt ttgctgaaga
    25201 gccgttacgt tttgtatctt tttaactggg tgaataagcg ttgattctgc agaaatattt
    25261 cgaaactttt gatttgaacc agtcgctaga atcaaacgat caaaatccaa tttttttcct
    25321 cctgctaaaa cgactttttt ttctttcaat cctattactg tcttttctgt gtaaacatgg
    25381 attcgatagc ggtcagtcag ttcttctttc gtgatccaag aaagttgttt ttcactggta
    25441 acctttcctt ttaatatcaa attgaacccg ctgggaatcc atcctaactt cgattgcttt
    25501 tcaatcaaat atatttcact tgttggcatc aattggcgaa gataaatagc cgcatgaatc
    25561 cctgcaaacg acccgccgac aattacaatg ttcatctgca ttcctctttc ttataaggtg
    25621 ttctactgct aacttctcaa tcagaaaaca cagtattcat aactcgcttt caaccttatg
    25681 atacatagcg atgcagcaga atcaaccctc tccatcatac cgtgttctag gtctgcttct
    25741 caataatgta ctagtggacc taattgaaga gtatcatttc tgaagagatg tttcaaaaaa
    25801 tgtactctta taaaagaaaa aaactcgcct tttacgtacc tctgtccaaa taggaaacag
    25861 aaaagaacga aaagacgagt tttagcgtgt gtaatgtaat agttagaata gacacatcat
    25921 ttatttttaa ttctttaatg cttcaacaac tgcttcgcct aattgatgag cagattgagg
    25981 attttgccct gtaagaagcc gcccatcaat ttgaaccact tctgaaaaag ctgctccaga
    26041 ctgatagttt gctccttttt ctttcaaagc atcttctgct aagaatggta cttcattcgt
    26101 tgtaccattt gcttcctctt cttcattact gaacccagtc actgtacgtc cagctaaaat
    26161 agattttcca gactcatctg taactggcaa caatcctaca acaccgtgac aaacagctga
    26221 gaccagccct tcatttcgat agatttgtga agcgactttc ccaagatcta ttgcttctgg
    26281 aaaatcccac attgttccgt ggccaccagc ataataaacc gctgcataat catttgcatc
    26341 cacatcatca ggacgtaagg tatttcccaa ggcccgattt ctgaaatctt catcttcata
    26401 ataggcccaa tcgatttcat ccatattcaa aacactttgc ggttctaaag gtacatatcc
    26461 gcctttagga ctgacaaaat ctgcatcgat cccatttttt actaatacat cataaaaatg
    26521 agtcagttca cttaaccaca aacctgtagg acgctcgatc ttttcgtact tttctacatt
    26581 tgttaatacg atcaatactt tcattttccc atcctctttc tataaaaatt gcgttattga
    26641 taacgtgctt tcaagaaatt atataatggg cttggcaaat aaagctcttt atatgctttt
    26701 tcaaaaggtt tcgttacaaa ttcatcctca cggttttcca ataatttctc tgcccagtca
    26761 ggatcgacga tcatttgctg tccaattgct gcaagttctg catatttcaa tacctgctct
    26821 acatcttcgc gattgcggat cccaccgaca ccaactaaag ggatctttcc ttgaatcgtg
    26881 ttatggacca cttcaagaat cgatttatcg ttgtatttat cagaacgagc tattcgatca
    26941 tacatattta atgaaacatg cagataatct agttttgact cacgtaatcg ttcaagaagc
    27001 cagatcgtgt cttcaaaacg gatacctggt gtttcatatt cttctggtga gaaacgatac
    27061 cctacgatga atggtttttt agcatattgt tcaaccgctg agaaaaccgt tgttaataat
    27121 tcttcaataa aacgataacg attttccaag ctaccgcccc attgatcctc tcgtctattc
    27181 gaatgcggag agaaaaattg ttggatcaaa tacgtatttg ctccatgcaa ctcgattcca
    27241 tcaaatcctg attcaatcgc tctacgtgtg gctttgccaa atgcttggat tgtttcaacg
    27301 atttcttctt cactcattgc tcgtggtgtt tccgcatcag gacgttttgc tgcaactgca
    27361 cttgcagata caggctgttc tccagataaa gttgctcgac ttgtcattcg tccaccgtgg
    27421 aaaatctgaa taatcgcttt tgcgccttct ccttggattg ctttcgctag ctcacttaat
    27481 cgaggaatca tttcatcatg agcgatgctg agttcacctg gccagccttt tccgatatct
    27541 tggacatttg cagcaccagt aataacagca ccaagacctt tagaacgttg tttataataa
    27601 gtgatctcat cttcggtgat cactccattg aaaaagctga gttgtgtcgt cataggcgac
    27661 agcatcaatc ggttcttcaa ttgaactcct gaaggtaaag taattgattg atcaaattgt
    27721 gacattgtca ttcctcccat aattcgctct gattaaccta tcgagaatca tctatcatta
    27781 aaccactcga ttagttgtac atgcaactaa tttgcttaaa aaattttatt ttttttgtaa
    27841 cttatctgtt gcatcattca ttgtctgggc taattcttta cttgcttcat ttcccaaaac
    27901 tgctttgtat gactgatgaa gttcttccca gctaccatcg acttccttag caaattggcg
    27961 tccttgttct gtaagataaa ctaatgacaa gcgaccttcg ctaactgttt tgacgtatcc
    28021 tttatattct aatttttcaa caaaacgagc aatcgttgat ggggcggaat agagcatttg
    28081 tgcaatatct ttttgtggta ttccatcttt ttcttttaat atcaataaaa taaaaccata
    28141 agttggtgcc agacctgtcc ttctaaacgc ttcatcagct aatttattca acatgcgatc
    28201 tagctttttc acgctaaaga aaagacattc atctaacgct ttttcaattg gcttttccat
    28261 ttcatcccct ccattggcgt acatatcata gtatgatttt tattttttgt caaaaaacac
    28321 ggaataatgt ccgcctcctc tgtctagatt tgaaaaaaag aagtagccat cttcaaagaa
    28381 tttcggcttg ttttcgacaa aactccttct ggaacaccgt gaatcagagg ttgtgaaaaa
    28441 gtcgtttagt tttgagtatg aagaaaaatt ttgtgaaaat ggctttccac atttttgcat
    28501 aaatttggct taataccgaa aaactggctt ttgaacaccg tttatatcag aggttgtgaa
    28561 aaagccgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct catattttgt
    28621 cgttttttga gctaatgccg atggtcagct gattgtacac cgtttattga gaggtcgtga
    28681 gcctgccgtt gaactccgag tcacaaggag caatttcaaa aaacagcttc tcatgtttta
    28741 tgactatggt gacttgtgat cgaggagttg gcaggagaat actgtttatt cgtaaagaag
    28801 gggctgtgac aagacttttg tcacagtccc ttatttcctt ttattatagg atttcgccat
    28861 ttgattggat gacttgtctg taccaatcaa atgatttttt ctttaaccgt ttctttgtgc
    28921 cattcccttc gtcatcttga tcaacataga tatatccata acgttttgac atttgtgaag
    28981 tagaagcgct gacgatatca atgcagcccc acgacgtata accaaataaa tctactccat
    29041 ctttgatagc ttccttcatc tgctcaatat gctgcttcaa atagtcaatg cggtaatcgt
    29101 cttgaacggt tccatcttct tctactttgt ctatagctcc gagtccgttt tcagctatga
    29161 acagtggttt ttgataccta tcatataatt gattcaaagc aattctcaaa cccttaggat
    29221 caatctgcca gccccattca cttgatggaa gatacggatt tttaattcct ccagttatta
    29281 agtttccttg gaccccttcc caattttctg gatgagcact gactgcacta gacatgtagt
    29341 agctaaaaga aacaaaatca acagggtagg ctgctaagat ttcttcatca cctacttcta
    29401 tttttaagtt gacacctttt tcttcaaaca ttcgttgcgt atacgctgga taatatcctc
    29461 ttgcttgaac atcactaaag aacaaagaag ttctttgctg ctcaattgtt ttttgaatat
    29521 catccggatc acaagaatac ggaacaagaa gctgatagct gatcatacaa ccgacttgtg
    29581 aacctttgat aatttcatga caagcttttg tagctaaagc acttgctata aactgatggt
    29641 gtgcaccttg gtatttcgct tgttccaaat ggggatggtt ttcttcaatt actcctacgc
    29701 taacaaaagg gtgatgtttt acacagttga tctcattgaa agtcatccaa tattttactt
    29761 tatttttata gcgtttgaat actgtttcag cgaaacgaac gtaaaactga ataagctttc
    29821 gattaggcca tccaccatat tctgtaacca aatataacgg catttcataa tgggaaagag
    29881 aaacgactgg ctcaatccca tattttagac attcgtcaaa cacttgatca taaaaaaata
    29941 atcccgcttc attgggtgtt tcttcatcac catgaggaaa aattcttgtc catgcgatag
    30001 acatccgata gcatttaaaa cccatttcag caaataaacg gatgtcttct ttaaagtgat
    30061 gatagaaatc atttccgtgt cttttaggat aataatactt gctgttggga tcctgcgccg
    30121 cttttacttg ctgatgcgtc atcatatgcc attgatctgt ccatttttct ttaggtaaat
    30181 cgctgtcgaa tgtatacaca tcagacacag ataatccttt ttcatctaca tcccatgcac
    30241 cttcacattg attggccgct gtcgctccgc cccataaaaa tccttctgga aattttttca
    30301 tatcgatccc cctaaacttg ctagttttct tgtttgatta tttttcttat gactagtaat
    30361 gatatttttg aatctactac tatttgtaac aataaccatt gtggtcggat catatccctc
    30421 tttgattaat tcttgcaaat ctacttccat caataaatcg cctttacgta ctttttttcc
    30481 atcagatact gcactttgaa agtatttgcc atttaaattc actgtatcaa taccgatatg
    30541 gatcagtatc tctgctcctt cttcactgac taccccaatt gcatgtttcg ttggaaaaac
    30601 tgttgaaact tccccgttta cagaactgta gatttttccg tccgttggaa tgatcgcaaa
    30661 cccttctcct aaagatccac tagcaaatgt tggatcgttt acttcagata aatcaattat
    30721 ttcacctgct gcaggagtac ttaacactat atcctttgag gattcttctt cgatttcatc
    30781 cttgtagccg aaaagaaaag ttagcataca ggaactgatc atcgctaaga aataactagc
    30841 aactagccaa acaaatcctt caccaatata aatcgggaaa gacaaaatac ttcttgtagc
    30901 aactgccaaa gcaccggctc ctgcggcacc agctactcca ccaaatatag ctccacatat
    30961 acaagcaatg taaaatggtc gtttatattt aagagtcaca ccataaacag caggttcagt
    31021 gattccaaat aatgctgtga taaatgcaga taaagataaa ctttttactt tcttattttt
    31081 cgttttcaaa aataccccaa gtactgctcc tgcttgcgca gctacggcag tcatacatgc
    31141 tggacctagc gtatcacgac cgtagaaaga aagattgttg gtcattactg gtacaagtcc
    31201 ccaatgtaac ccaaaaatca ctaacacttg ccaaaatccg ccgataacag caccagataa
    31261 aacagggcta aagttataaa cagctaaata tccagctgca atcagctgac ttgcataatc
    31321 tgcaattgga cctacaacta ataaaataat tgggaccatc acgatgatac aaatgaatgg
    31381 tgtcaataaa tttcgaatac tttcgtgcaa gcttttgcga atcttaggct caatataaga
    31441 aagaacccat acagctaaaa ttgctggaat aaccgtactt gtataccttg ctagaatcac
    31501 gggcatccct agaaatcgca aggttatgct atcactatat gcactgacaa tcgtaggata
    31561 aacgagagct gctgcaataa ccatagcgat gaaacgatct gtattgaact tttttgcagc
    31621 agtatatgcc aaaaatatag gcaagaaata gaaaaatgca tcagctgctg cattcaaaat
    31681 gatataagtt cctgattcag tagttaataa attcaaactc gtacataagg cgagtactcc
    31741 tttgatcaaa ccacttcctg ccaagacgcc taaagtcggg gcaaaaacag cggcgatcat
    31801 gtctataaaa gagtttaaaa tgcctttttt ctcagttcct ctctttccac tagatgcatc
    31861 atcttctagt ttcatttgtt tggataatac gtcatacact tcatttactg catttcctac
    31921 tacgacttga aacattcctc cagcttcgac tacagtgatc acaccttcta gttgctctac
    31981 cttctcctta tctgccttct tattatcttt tagggtaaag cgtaaccttg ttgcacaatg
    32041 gtaaacattg ctgacatttt cttcgcctcc gacaaatcgg acaatatctt tcgctaattg
    32101 tgaatagtcc atttttactt cccccttgtt aattaatgcc gtagcaatcc ttcttacaag
    32161 ataagtatag ttcttagaaa acggtttctc cattcaatta gtaccccttc taatagcgaa
    32221 cgaaactgta caatagtgtg tatggtttac ttagccgagc aaatcactca ctgcttgaaa
    32281 gaaaacaagt atatcgtttc tcttatagtc aaaggagaca aaaaaaacac gcttgatctt
    32341 cctttgctga tgtataagtg gtatctcaag ctgatactct gtgatttttg tttctacttg
    32401 gcttttgata agacagcaca acaaagtctc ggcatttaac ggaagcataa ctaggtcaga
    32461 actaggagag attagttgct gaatggaatc tatcttttta tggattttta tttgattttc
    32521 ttctttgtag taatgatcaa gcagttttgt tttctttttt tcttcaacta tggtcagctt
    32581 ttcacgcaaa atctgataaa tctcccaaga ttcaaactca tctagaacac taggtagata
    32641 aatcaaatca tcccactcaa aaataagctc ttgctcagta gtcaaaattg catcatattc
    32701 cgttattttg tttgattgat ttttgaaaag atacactggt tctatccggc attctttgat
    32761 ccacatgttc atactttgtt gaatctgttt ttttagtgta ttcaaaatac taattggctg
    32821 gttactaaca atcagtatct ccccttgttt tcgaaaagga ttcaacgctt cggcaagata
    32881 caaaacaaaa taagcgcttt cagctaaatt gggacgtaat tgaaaatgta ttgggaagaa
    32941 acgccgaatt aaataaattt ctaaaggata acgggagatg atcttttgta caaaatgatt
    33001 catggtatta tgtccggcat ccatcctcgt tttcatttgt ttgatatggg ttagcaaaaa
    33061 ttctgtttca tggaacaata acgaaacagg aagatctaaa aaacgaataa tcgtttgctc
    33121 aaatgctctt agattcttct ctatttcttt gtttttttca tcattaatca tcaaataatt
    33181 taactctaat agtcgatttt caattgcttg tttttcttga ttggaaaaag aatagggtag
    33241 ttctgatgat aacttttttg tgagggtctc taccatcgga ataaataatg tatacctgtt
    33301 tgttttttct aaaagttctt ctcttcgaag aatggtcaaa acgagatacc gagaaaatcg
    33361 tatgaagtcc tctcctgaaa caatataatt atatgatata agaacctctt ttaatgtctt
    33421 ttggacagtc ggcatgatat tggaaaaaat tgtactgatt tgttgaggaa accttgcgtg
    33481 ttggatcacc gtttctgttc caacaagaga taagaaaatt ctttttgaat tttcttcagc
    33541 aatgattttt agtccttttg tcgacgaaac ttccagttct aatttaggat tgcgctcgat
    33601 ccaacgcaaa atcgttttta tttgtaatga tacggctgtt tttgaaagaa agaaaatgtc
    33661 tgctatcttt tgcatactga catacccttt ttgaaacaat aagtacgtca caatagttga
    33721 agctcggaaa tccatgctgg aatagatttt atgtttcgtc acctcttgta tgatttgctg
    33781 tttagtttca gattcaattg attctaaaaa ataacctgaa cgtttatttg actggataat
    33841 gattttcttc tcgtagatag caagcatatt tttgatttca gtttggatcg ttttcttgtt
    33901 ggtacctaaa gcttcagcta attcttcgct tgttatccaa tgattcttat ttcttaatac
    33961 tacaagaatt tggagttgtc gtttatttaa gtccatttgc ttacacctcc tctttgttat
    34021 aaacatacag gaaaaacctc tcaaatgaca atagtcactt gcagaggttt aaaaatcatt
    34081 tgaagaaaga tctatattca aggtttttac cattagactg gataatttgt ttataatatt
    34141 caaaactatc ttttttcaat ctcctaaagc ttccgctccc atcattttgt ctatccacat
    34201 aaataaagcc atatcgcttc ctcatttccc ctgttcctgc cgatacgata tcgattggtc
    34261 cccaccataa gtaaccaatg atttggcaac catcttttat tgcctcagca atttcctgaa
    34321 gatgtatttt tagatactca caacgttttg gatcgtggat tcgattcaat tcatctggtg
    34381 cttcatctag tccaatgcca ttttcaacta tgaataatgg taattcataa cggtctgtca
    34441 attcattcat gacataacga aaccctagag gatcaattgg ccaactccaa ggttcgggag
    34501 atttttcctt caaaaaggga ttatcgaaac catttgctcc gccagtatct acgcgcattt
    34561 ctgcttcttt tttatagaca gcgctacgat aataactaaa tgcaatataa tctgccgtgt
    34621 tagcttgcaa gcactgttcg tctccatcta acattactgg tgcacagtct tcttccttcc
    34681 atgtcctgta aatataagct ggataatgcc ctcggcacat gacatcggag aaaaaccatg
    34741 aattgcgttt aaattgcagt gaaccaaata cattctctgg atcacagtca tatgcataag
    34801 tcgctaatgc agaaaagcta cacataatac ccatcttagc atttggatcg attttcttta
    34861 ataattgagt agcacgggcg ttcgctagaa acatatgatg acaggcttga taaatcactt
    34921 tttttgttag tgtagcaatg ggttcaagtt tatctctagc agggaatgta accaatccag
    34981 cagctgcata aggcatacga aaagcattat tgatctcatt aaaggtcatc caatatttca
    35041 ctttcccttg gtagcgttca aagacggtct gcgcataaaa ttcaaaaaag tcgattaatt
    35101 ttcgattttg ccacccccca tactctccta ccaatgctaa gggggtttca taatgactaa
    35161 gagtaattac tggctcgata tcatatcgat ttaatgtatt gattagtctg tcataaaata
    35221 cgagaccagc ctcatttggc ttctgttcgt ctcctcttgg aaatattcgt gcccatgaga
    35281 tgcttgttcg aaaagctttt aaacctaact ccttcagtaa acgaatatcc tcttcaaatc
    35341 gatgataaaa atcaatcgct tcatgagaaa gataatggag tgattcgtct aaagcaatct
    35401 cccaaatctt tttttcttca ttccactgaa tactaggatg ctggttcatg atcccgataa
    35461 gcgtatctgt cacattaggt aatttgccgt cttccaacca tgcaccttca cattgattag
    35521 cagctactgc tccgccccat aaaaaatttt ctggaaatat ttcctgatcc ataactatct
    35581 ctcctcgcta tcaacaattt cttacttgaa gtatagctcg attcatcaaa acaagatatt
    35641 ctaactattt cggcagaaga gaagaaaaaa attgaatgct actcttcatt tttaatattt
    35701 atatataaca aatacataag acgatccccg aaagaaaaca ctcgttaacc atctaagcaa
    35761 acgatttatt ttacttccaa cacaaatgct tcataaggtc gtaaatcaac tttgccgtct
    35821 ggtaactgtt tcagaggata atttgacaca ataaccctta aagcttcacg tggaatagtg
    35881 aacgtctgct tttcactgga catattacaa ataacgagcc attgctggtc ttcatatatg
    35941 cgagaatagg caaagacatg ctcaggcgtc ttttccacta attcatagtc tccccagacg
    36001 atgatgtcat gttttctacg caaatcgatc aatttcttgt acatataaaa aacagaatct
    36061 tgatctgcta acgcttcttc tgcattgatt tctttataat ttggattgac tcgaagccat
    36121 ggaattccag tagtaaaccc agcatgttca cgggcgttcc attgcatagg cgtcctagca
    36181 ttgtctcttc ctttcgcctt gattgattcc aagatttcct cttttgtaaa tccagaagaa
    36241 atcctttcgt tatacatatt gattgtctca atatcttttg cttccgcgat atcatcgatt
    36301 gggcaattcg tcatgcctaa ctcttctcct tgatagatat aaggggtgcc tttcatcata
    36361 tggagcaaga tagcaaacat cttggcactt tcttttcgat acacatcgtc atttccccaa
    36421 cgagaaacaa ttcgcggaag atcgtgatta ttccaaaata aactattcca tccttcatca
    36481 cctaaagatg tttgccattt ggataatact tttttcagtt cagagatact caagggtttc
    36541 aaatcccatt tgtctttgcc ttcttgctga tctaatccta tgtgttcgaa ttggaagacc
    36601 atggataatt catttctttt aggattggaa taaagtttag cgatttcggt agttgctccc
    36661 catgtttcgc caacagtcat cagatttttg tcaccaaaag ttgcttgatt catttcctga
    36721 agatactcat gcagtttagg tccattactt gtgatttctt tatccggttc tttgccaatc
    36781 atatcgatca cgtccatacg aaagccccca atacctttat cgatccagaa attcatcatt
    36841 tgataaatct cttggcgaac ctgtttattt ttccaattca aatcaggttg acgcttgcta
    36901 tacaagtgca gaaaatattg ccccgttttt tcatccaact gccaagcaga accactgaat
    36961 attgagcgca atctattagg ctcttttcca ttgaccggat cacgccaaat ataatagtcc
    37021 cgataaggat tttctttatt tttacgggcc tcaatgaacc acggatgttc atcagaagta
    37081 tgattcacca ccagatccat gatgatacgg atatttcttt tctttgcttc ttcaatcagt
    37141 tcttccattt cttccatcgt accgaattct gccatgattg cttgataatt actgatatca
    37201 tacccattgt catcattcgg agactcgtat actggagaaa gccaaattgc atcaatacct
    37261 aaatacgcca gataatccaa cctggaaata atcccccgca aatctccaat accatcttga
    37321 tttgaatctt gaaaacttct tggatagatt tgataaacaa ctgaatggtg ccaccatttt
    37381 tgttccatga ttttcctcct ataaatggat gtttctattt tttgcttaat catttatttt
    37441 agtctctctc actaaaaatt gtaacgcttt caaatagcta ttgcaccttg ttatcggtaa
    37501 cagaataaaa caaaaaaaca gctgaggaaa ttccctcaac tgttttttga aaggattgat
    37561 ttatgcaggg aagaatgctg atttcacaac ttctttataa acggtgttca ctcagctgtc
    37621 ccttggtatt agctcaaaaa acggcaaaat ataagaaact attttttcgt ttttttctct
    37681 aatactcagg ccagaacgct gatttcacaa cctctttatt tcacattcaa tatccacatg
    37741 aatcccacaa atacaaagaa cagaccatac atgattggag atacttcttt tcctctttta
    37801 gctgctaaca tggtaattgg atagaagata aaacctaatg caatcccatc tgaaatacta
    37861 taagtcaaag gcatgccgat caagatcaag aatgaaggga tcgcaatctc taagtttccc
    37921 cattcgattt gtcgcaaaga ttgtgccatc aatactccta ccataatcaa tgctggtgca
    37981 gttacttgtg aagtaacaac tgatagtaat ggagaaaaga acaagcctaa caagaagaaa
    38041 atccctgtag taatagctgt gatacctgaa cgtcctccaa cggcgatacc agctgatgat
    38101 tctacaaatg caccaacagg agaagtacca aataaggaac ccgcaagcat agctgttgaa
    38161 tcagaagcta aagctttccc tacacgaggc atcttgttgt ctttcatgaa acctgcttgg
    38221 tttgctaatc caactaaagt tcctgctgta tcaaagaaag tcacaagcaa gaatgtcagc
    38281 actacgaccc acatttgaag agaattgatg tcccctacat gttttaatgc aactaaaaat
    38341 gttggtttca aacttggtgc tgcggcaaca atttcagaag gcattggaat caaacctgtg
    38401 accagaccta aaatcgttgt agctgccatc ccgatgaaga tgccacctgg tacacgccga
    38461 acaagcaaga tagcagttac gactaatcca aaaatcgtca accaagtaga accaacgttg
    38521 agtgatccta atcctactaa tgtagattca ttcgaaacga tgatcccacc ttcgctcaga
    38581 ccaaggaaag cgataaatag accgataccg ccagaaatcg catatttcaa atctgctggg
    38641 atcgcatcaa tgatcatttc ccgcagcttg aagattgtga tcaaaataaa aatcaaagaa
    38701 gcaacgaata cgccggctaa tgctgtttcc catggaatcc ccattcctaa acaaacagaa
    38761 taagcaaaaa aagcattgat cccaagagca ggtgccgttc caattggata acgggctaat
    38821 acccccatta aaacacagcc gatcgcactg gctaatgcag tcgcagtaaa cactgctcct
    38881 tcatccattc cagaagcacc taatacagtt ggatttacaa ataagatata agccattgag
    38941 ataaatgttg taaatcctgc cagtacctca cgttttaccg tggtgttcaa tttttctatt
    39001 tcgaagtagg aaagtatttt ttccttcatc ttccatcccc ctaaatccga acattataaa
    39061 taaagtccgt taaaatttcg atttattaat aaaacaacgt gttttatcat atactaaaac
    39121 aaaacataag taaacaaaaa attcggattt taagcaaaat ccgaacgttc catctgatta
    39181 aatcccttta tctcaaagtt catgaacatt cactttggat tacaagaatt tctttattgt
    39241 gttaataaag tttcttcatt ctagtctcaa aaatcaatag tgtgatttga ttttaccatt
    39301 tcgtttctgt tcttctttga tgaattcttt tgtatcgaca ggattcagat tatttagtcc
    39361 gccaaaacct gtatcgacca tttttcccca gccttttgtc ttcttttttc ctgatttgag
    39421 attctttgct cgaagcttct cactatgttt tgctcgccga tacttcaaat aaccttctaa
    39481 tcttcccatt agatccactg tttttcctcc tttttattca atcagacgac tcagcttttc
    39541 ctataacaaa ataattgcct tcagggtcag aaaaattgaa agtcaagatg ccattgttat
    39601 ctgtgatttc tcctggttct tccatgttct cgtagatagt ttcaaattca tccgtaaaaa
    39661 atactaaaga aggcggtggt cctaatacct ctggtgaaaa cttctgcaca aatacttttg
    39721 ggaatacgcc taattctaat tcttttgaga tgctgagtac aatactctta aattcttctg
    39781 gcaattcgat tgtttcagaa atttctgcac caattttttc tacaaagaat cggcaaatca
    39841 tctctacgtc attgacataa agcatcacac gtgttttttg tatcatcatt tgacccttct
    39901 ttctatttga ttttctttcc tgtctataaa ctgattccat tatatcacga aagcgcaaac
    39961 accttgtgtt tgatactatt caagaaaaat aaagcaatag tttctaggat tgctttcctc
    40021 cacaaacttt ttttacaaaa aaaaaacggc aatgaatgcc gctcttctta tttcgattct
    40081 tttataattc tgcttctgat tcatctttgg ttagtgtgtg tctaacacta gttacgccaa
    40141 atgtttgatc gattttttcc ttcaacgctt cgattgcctg tgcgccacgt gccgcttgtt
    40201 cagcattgat ggattcaatg accagcaccg ctgcttgtgt ttcttccgtc agcatcgttc
    40261 tttgggcttc acgccagttg agacagcgac agatcgctcc ttgttcatca tagtagatga
    40321 tttcttccgg aagtgccgga gcatcggaat ctgcacctaa aggcaggaat gattcgccac
    40381 cttgggcttt tcctaaatgc agatttcctg cgatcttttc gatatcttct ccgccgcaag
    40441 gtacgccaaa agacaaggaa atactattat agatatctac aagcggattg attgggaaaa
    40501 attcccgttc ttgatttgca cgtttcagta aagcttcaat agaagaacgt gcaccttttt
    40561 tagtcttgaa tgtggtaaat gcctgacgcc actgagcaat gacttcgttt tggctgaatg
    40621 tttcttctgt aaggtaattt cttgcttctt ttgctgcctc attcaataat tgatgatacg
    40681 tttcttcact ttcttttgtt acgtggttat cgataccatt tacggataag atttcgatgg
    40741 ttgcttcagg aaatacttcc cagaaattgg tatccactat tacttttttc atctgttcac
    40801 acctcttgat tagaataatt gcttgatgaa tagatagtct gtttggggat catctcccat
    40861 ataaaaaaca tgttcgctgt atttgataaa tcctttttta cgataaaaag cgagcgcaac
    40921 atcgttgtgt tcccaaacac cgagccaaat ggctgttttt tgcttttctt ttgctttttc
    40981 aatagctgta tctagtaaaa atgtaccgat accttgatgt ttaaattttt ttcgtacata
    41041 gattcgctcg atttctaaaa aatgatcagc catttcctca gattgactcg ttcctgtatt
    41101 tagtttcagg taacccgcag gctcttgatc gatactcact aggaaaaaat cggtttcttt
    41161 atcttttagc tcttctgtaa gtttttctag tgcataagct tgtgtcaagt aatcagctaa
    41221 atgctccggt gaattatctt ttccaaatgt atctgtaaat gtttcgatac taatttgttg
    41281 tagtaagtct acatctgaag gcgtcatttt tcgaatttcg tatttattca cggcttcttc
    41341 ctttcaatag atccttttat tgcctttttt gacaaaattc caatcttcgc taacattctt
    41401 gcatacttta tttaaaagat attccaattg ttttgcttct tcgtcagaaa gaccatttaa
    41461 tgcgactgca ttggagtagt tgttttctcg aatgatgaaa ggatagattt ctgctccttt
    41521 tttagtcgga tagagtttct tgattttttt attttcttta tcttccaaac gttcgatcat
    41581 cccattggat tctaatttct tgattgctcg ggcagtcgtt gtacgatcta ctttgatcat
    41641 ttctgctagt ttttcttgga tgattccagg attttcgcaa atacgtacta aataaagata
    41701 ctgtcctctt gttaaatcga cttctttgaa ttcgatattg ctaatagaat ctagcgctcg
    41761 ggcaatcatt ccgatgtctc gaaggatttc agccatttca tcccaccttt attttgtttg
    41821 taagactagt tcacctcttt ttgttgcaaa tgcaactatt ttcaataaaa aaatcaagtt
    41881 cttttttaat aactagtaaa gtatattctt ttcttctttt acgaaaaagc tcaatcacaa
    41941 tagatctggt ttttgttttc taaaataagt aactgtttct tcgttgttcg cttttctgat
    42001 agctttggca actcttctat actaaaaaat cccatgttgg aagtttcatt attctcaata
    42061 aacttggcct cttcaccgtg gatcgcacaa gcaaaaacaa gtttataata ctgaaaaagc
    42121 tgtggaatat ctttttgttt attcgtatca aaaactgctc gcaactgagt agtttctact
    42181 gttaatcctg tttcttcata gacttcttta cgcacatttt cttcaggaga caatcctatt
    42241 tcagcaaatc caccaggaag tgaccattct ttcgtccgtt tatcttcgat tagtaggacc
    42301 ttgccatctt ttttgatata ggcacgaaca tctacttttg gtgttggatg tccttctcca
    42361 atcgttgtga gcgcttttat ttcttcgaaa gtttcttttc ctatttcact gatcagttcc
    42421 aatgaaatcg tccggatctc ctcaaaacgc tctttatcaa atacatcttt tccataatat
    42481 agaccagctt gagaaagtgc gagtagtctt ttgtattgag ccaacttctt gttcattctc
    42541 ttcccttctt ttttagcaaa tgtatgacta tgtaatcaag tatagaagac tggtttaatt
    42601 acggcaaata aatataatga aatctgcaat aaataaaaga atgttaaaaa actcgagaac
    42661 aaaagacatt cgacttctct ggggctgtga ataaatggcg ttcaaaagct tgcatctgcg
    42721 gtaataagcc ccaccaaacg aaaaatatga cgagctattc ttgtctggct gttcttatta
    42781 attgaggcag gacagctttt tcacaacctc cccactaaac ggtgttctcc taccaactcc
    42841 tcggtcacaa gtcacaatat tcatcaaaca tgagaagctg tttttttgaa attgctcctt
    42901 gtgactcgga gctgaacgac aggctcacga cctctcggta aacagcgttc aaaagccaat
    42961 ttttcgatat taagccattt ctttgttact tattgtcatt gatttctttt tctaatttat
    43021 ccaatagtgg agtgtaatcc acttgagtat agtctgttac atcaaattca tatagtgttc
    43081 ctaactggaa tttgtcatat tttcggtcgg cgatgatctt tttgaatgct tctttcgtaa
    43141 tatgattggt ccctttcgtt cgatcttcca atacgtcacc atagtgataa tgatccatga
    43201 tatagctcaa atgacgatct gattcacgat cacgtttgta ccgacgttgc cataacactt
    43261 caaagtctgc tgttaggcga atcgtgatca cctgatatcc gtatctatct gctaattctt
    43321 ggagtcgtgc tttttgctta tcactaaaag gatactcgga cacaatcact ttctttcctg
    43381 cttccatata caaatcaagt gctttgtaat agaaaggata aactttcgtc ctttcttgtt
    43441 ccgcccgttc ttccaaattg ttaaacccga tggattctgc atagtattcc ttgatttcat
    43501 cgagcgtgat ggcatacata tctggaaatc gttcccgtag tttattcata agatatgttt
    43561 ttcctgtacc aggactacca gccagaagaa tgaaatactt tttcatctca tttatttcct
    43621 aagttaattg gactttccaa gttcataaac agtccaatct tatgcttgac aatttctttt
    43681 actgcttcat ttgctggaat cacattatgg cgaagagact tgttgatttc tgtttcacta
    43741 aaggtttctt tagctacttt cgtccagttg actaaaagct ccgttccaac attgaatttg
    43801 cggatcccgt tattgatcaa ttcaggataa tcttcttctt tcacacctgt tcctccatgg
    43861 ataactaggg ggacatcaac tactgcatcg atttctttca gcaagggaat gtttacttct
    43921 gtttttgatt tgaattgtcc atgattcgta ccgatagcaa tagctaatgc atccacgcct
    43981 gtagcttcta caaatttcac tgcgtcttcc ggtcttgtat ataccttgtc attttcagcg
    44041 acatggattc cttcttctgt accgccgatt gttccaagtt ctccttctac ggaaacaccg
    44101 tgcgcatggg catattctac tactgctttt gtcttcagga tattttcttt gaaaggcaga
    44161 tgggacccat catacatgac agaagtatat ccgctgtcga ttgcttcttt gatatcatca
    44221 aagtctcggg cgtggtctaa gtgcaagact gcatcaacca tttcttcttc tgcaatagct
    44281 gtcattacat tgactaacac atgcatgccg atatatttag cggtatcgac acttgtttga
    44341 ataatgatcg gcgaacccat ttcttttgct gcgcctagca tagcaggaag catttctagg
    44401 ttatgcgtat taaaagctcc aactgtaaaa ttcaactctt ctgctgtttt tgttacttct
    44461 ttcaatgttg tatacatctt ttattgccac cttatctttt tatttgtttc ctttgatcgt
    44521 tacttgtttt gcaatttgtc gcatctcatc cattttgccc atgtagtaat cgatcccttg
    44581 atcatcacca gcacgagcag catctgcacg cttctggtta tagaggctca tcagtttttt
    44641 atacccatct ccgatcgtct gtttattttc caaactcttt tctaaatatt ggatggcttg
    44701 atcgttcaca tacaattcag aaaatttaag tccaacttgt tcataaagtt tcgctaattt
    44761 atgcttatct tgggtagtgg aaatctcttg tttcaattgt gtaatctctg attgaatctt
    44821 ttcggtcgct tctggcgata gggctttttc ttcttttgcc agaacttttt tcggttcttt
    44881 ttcttttttc ttaaaaaatc caaacatcat tttccctact ttcaattaaa atgctttcaa
    44941 aactgggctt aagatccagg catataagag tgctgcggct actgtatcta catcggttgc
    45001 tgtagcattg ttgaatccca tcgaattaaa gatcgttact agcaaagcgg gcaataatgt
    45061 aataaagaaa ccatgagcaa taccgccaat gatcgctcct cggcgtccgc caactgcgtt
    45121 gccaaatatc cctgctgtcc ctccggcaaa gaaattggtt agcataccag gtaaaatcat
    45181 cgctaagccg aacatgggca aagtaaacat ggcaataatc gtaccaatcg ttgtcgtaat
    45241 gaaacctaaa atgacagcat ttgggctata aggaaagaaa actggacaat ctaaggcagg
    45301 gatcgcatca ggaactaatt tcatagctat ccctcgaaat gccggcacga tttcacctaa
    45361 cagtagacgt acaccagcta gcaatacata cacacccact acgaattgga tggcttgtaa
    45421 aaaggcaaac atgatatagt tttgatctcc tgataattca gaagcgaatg gttcgcctgc
    45481 aaataaaaca gtgatgatat atagcgggac catcacgacc atgacagaca aataagtatc
    45541 ttgcagaaat tcgaaatgtg tcggcaactt gatatcttcg atcgactttt tattttcgcc
    45601 tttctcacca aaaagcttag caacaccggc ttcaaataag tacccgatcg tacaaaaatg
    45661 acctaaagca atatcatttg atccagtgat tttacgaatg atcggttgcg ctactgccgg
    45721 catagcaatg gcgaaacaag ctccgataaa accaccgacc aagatcaata cgatccctcg
    45781 cagaccggca aaatagccaa agactgtcgt catcgttgcc atccataaaa ttgcttgacc
    45841 agttaaaaaa atgtacttcc attttgtgaa acgagccaaa ataatattga atacaaaaat
    45901 ggctaagaac gtcagtgcaa tatctctacc taaacccaaa tcattcattg cttgaccatt
    45961 gatagattca atagaaggga tgatcccttg catatgaaat ccttcagtaa agattttccc
    46021 gaaataagtt aaacttccaa cgatgatgct cgaaccggca ctcaacactt gaaatcctag
    46081 gagtgtcttt aacgtgccag agatgacttg tcctgctgat ttcttctgca gtagtagacc
    46141 caacatagca atcaatgcaa tggtgatcga tgcctgagtc aaaatatttt cgatgataaa
    46201 attgataacg cccatgtttt gatgtgcacc ccaaaagtta gactagaaat ctaattaaaa
    46261 ggggtgcttt ttttgcggaa atatacattt gtttttaaga aaaaagtagt ttcagactat
    46321 ttaaataacg aaggcggcta caaatatctt gcacataaat atcaaataaa tcgtacactg
    46381 gttagacatt gggtaaggat ttataactat catggttggg aaggcttggt tggaggtggc
    46441 aaaagctaca ctacaaaatt taaacttgat gttatagaat atatggaaac aaatggtctt
    46501 tctatccaag aaactgctaa aaaatttaat atcggttcaa atagaactct aagtaaatgg
    46561 atagagcaat atgaagaagg cggtgcttct tcacttgaga gccaaaaaag gggcagaaaa
    46621 attagtatga attccaagct aaacattcct aaaaaactta aagatgagtc tcttgaagaa
    46681 gaagttattc gtttaagagc ag
//
LOCUS       DAZKNV010000018        46155 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000018 DAZKNV010000000
VERSION     DAZKNV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.018"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(449..979)
                     /locus_tag="ACG8M1_001098"
     CDS             complement(449..979)
                     /locus_tag="ACG8M1_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFQ0421824.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            1084..1635
                     /locus_tag="ACG8M1_001099"
     CDS             1084..1635
                     /locus_tag="ACG8M1_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0421825.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(1788..2261)
                     /locus_tag="ACG8M1_001100"
     CDS             complement(1788..2261)
                     /locus_tag="ACG8M1_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0421826.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            2399..3871
                     /locus_tag="ACG8M1_001101"
     CDS             2399..3871
                     /locus_tag="ACG8M1_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFQ0421827.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            3868..4578
                     /locus_tag="ACG8M1_001102"
     CDS             3868..4578
                     /locus_tag="ACG8M1_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFQ0421828.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            4930..5214
                     /locus_tag="ACG8M1_001103"
     CDS             4930..5214
                     /locus_tag="ACG8M1_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFQ0421829.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(5495..5914)
                     /locus_tag="ACG8M1_001104"
     CDS             complement(5495..5914)
                     /locus_tag="ACG8M1_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFQ0421830.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(5916..6500)
                     /locus_tag="ACG8M1_001105"
     CDS             complement(5916..6500)
                     /locus_tag="ACG8M1_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFQ0421831.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(6547..8022)
                     /locus_tag="ACG8M1_001106"
     CDS             complement(6547..8022)
                     /locus_tag="ACG8M1_001106"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFQ0421832.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            8203..8514
                     /locus_tag="ACG8M1_001107"
     CDS             8203..8514
                     /locus_tag="ACG8M1_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421833.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(8629..10965)
                     /locus_tag="ACG8M1_001108"
     CDS             complement(8629..10965)
                     /locus_tag="ACG8M1_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFQ0421834.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            11107..11775
                     /locus_tag="ACG8M1_001109"
     CDS             11107..11775
                     /locus_tag="ACG8M1_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0421835.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            11778..12821
                     /locus_tag="ACG8M1_001110"
     CDS             11778..12821
                     /locus_tag="ACG8M1_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0421836.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(13058..13939)
                     /locus_tag="ACG8M1_001111"
     CDS             complement(13058..13939)
                     /locus_tag="ACG8M1_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0421837.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            14098..14826
                     /locus_tag="ACG8M1_001112"
     CDS             14098..14826
                     /locus_tag="ACG8M1_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFQ0421838.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            14982..15299
                     /locus_tag="ACG8M1_001113"
     CDS             14982..15299
                     /locus_tag="ACG8M1_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0421839.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            15292..15900
                     /locus_tag="ACG8M1_001114"
     CDS             15292..15900
                     /locus_tag="ACG8M1_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFQ0421840.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            15955..16746
                     /locus_tag="ACG8M1_001115"
     CDS             15955..16746
                     /locus_tag="ACG8M1_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFQ0421841.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            16884..17372
                     /locus_tag="ACG8M1_001116"
     CDS             16884..17372
                     /locus_tag="ACG8M1_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFQ0421842.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            17423..18295
                     /locus_tag="ACG8M1_001117"
     CDS             17423..18295
                     /locus_tag="ACG8M1_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFQ0421843.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            18471..18833
                     /locus_tag="ACG8M1_001118"
     CDS             18471..18833
                     /locus_tag="ACG8M1_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0421844.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            18842..19594
                     /locus_tag="ACG8M1_001119"
     CDS             18842..19594
                     /locus_tag="ACG8M1_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421845.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            19608..21410
                     /locus_tag="ACG8M1_001120"
     CDS             19608..21410
                     /locus_tag="ACG8M1_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421846.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            21687..22727
                     /locus_tag="ACG8M1_001121"
     CDS             21687..22727
                     /locus_tag="ACG8M1_001121"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0421847.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(22779..24923)
                     /locus_tag="ACG8M1_001122"
     CDS             complement(22779..24923)
                     /locus_tag="ACG8M1_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0421848.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(25280..26653)
                     /locus_tag="ACG8M1_001123"
     CDS             complement(25280..26653)
                     /locus_tag="ACG8M1_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0421849.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSSKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(26653..27048)
                     /gene="rbsD"
                     /locus_tag="ACG8M1_001124"
     CDS             complement(26653..27048)
                     /gene="rbsD"
                     /locus_tag="ACG8M1_001124"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFQ0421850.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(27076..27993)
                     /gene="rbsK"
                     /locus_tag="ACG8M1_001125"
     CDS             complement(27076..27993)
                     /gene="rbsK"
                     /locus_tag="ACG8M1_001125"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFQ0421851.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(28101..29114)
                     /locus_tag="ACG8M1_001126"
     CDS             complement(28101..29114)
                     /locus_tag="ACG8M1_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFQ0421852.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(29195..29794)
                     /locus_tag="ACG8M1_001127"
     CDS             complement(29195..29794)
                     /locus_tag="ACG8M1_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFQ0421853.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            29980..30681
                     /locus_tag="ACG8M1_001128"
     CDS             29980..30681
                     /locus_tag="ACG8M1_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421854.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            30691..33402
                     /locus_tag="ACG8M1_001129"
     CDS             30691..33402
                     /locus_tag="ACG8M1_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFQ0421855.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            33853..35481
                     /gene="treC"
                     /locus_tag="ACG8M1_001130"
     CDS             33853..35481
                     /gene="treC"
                     /locus_tag="ACG8M1_001130"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFQ0421856.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(35541..36722)
                     /locus_tag="ACG8M1_001131"
     CDS             complement(35541..36722)
                     /locus_tag="ACG8M1_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0421857.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            36974..38497
                     /locus_tag="ACG8M1_001132"
     CDS             36974..38497
                     /locus_tag="ACG8M1_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFQ0421858.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(38566..39294)
                     /locus_tag="ACG8M1_001133"
     CDS             complement(38566..39294)
                     /locus_tag="ACG8M1_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0421859.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(39307..40587)
                     /locus_tag="ACG8M1_001134"
     CDS             complement(39307..40587)
                     /locus_tag="ACG8M1_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFQ0421860.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVALIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(40728..41330)
                     /locus_tag="ACG8M1_001135"
     CDS             complement(40728..41330)
                     /locus_tag="ACG8M1_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFQ0421861.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            41575..41781
                     /locus_tag="ACG8M1_001136"
     CDS             41575..41781
                     /locus_tag="ACG8M1_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421862.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            42093..42812
                     /locus_tag="ACG8M1_001137"
     CDS             42093..42812
                     /locus_tag="ACG8M1_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0421863.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(42893..43576)
                     /locus_tag="ACG8M1_001138"
     CDS             complement(42893..43576)
                     /locus_tag="ACG8M1_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFQ0421864.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            43794..45980
                     /locus_tag="ACG8M1_001139"
     CDS             43794..45980
                     /locus_tag="ACG8M1_001139"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFQ0421865.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        14919 a         8201 c         9223 g        13812 t
ORIGIN      
        1 ttttttgctg ggagcattat ttcattttga agtcactaat ttaactgtgt gaatatgcag
       61 ttgttacaat ctttgataaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa
      121 cggcaaaata tgaggaacta tttttccatt tgtttctcta atactcaggt caaaacgctg
      181 atttcacaac ctcttgataa acggtgttca aacggctgct tctcggtaat aagcccacta
      241 gcctagaaaa tatgaaaagc tattttctaa ctagcgttct tattactcaa agcataacgc
      301 tgatttcaca acctcttgat aaacggtgtt caatcagctg accctcggta ttagctcaaa
      361 aaacggcaaa acatgaggaa ctatttttcc gtttctttct ctaatactca ggtcagaacg
      421 ctgatttcac aacctctctt tcacaacctt attttactcg tttataattt tcatcgaagt
      481 attttccgct acggatatca tctggcattc catcgtatgg ttcttcgcta ataacatctt
      541 cattgtctat acctgcatca cccatataag tgatcgtagc aaattcagga acaagtaatt
      601 ttggataagt ttcatatttt tcacgagctg cttccatttc tgcgatatgt tcgttttgga
      661 aagtaacagt gatttctgga tgttcttcaa cccatttagg gaaaaagatc attccgtgaa
      721 gtttcttttc atttggcata aagtccaatg ccacgtctgt ccctgttggc tctgtccaag
      781 tgattttgaa tacgccgtcc gtcaatttaa cgatatcagc ttcttggtct tttacccaac
      841 ggcctttgac cattccgcca tggatacggt aatcaacagt atggtcattt ttggcatacc
      901 attcatattc ccaaccattg tcatacgtat agataaagtg agttccaata aaatcttcca
      961 attctttaaa ttctttcatg tttaagcatc tccttataaa ttaaaacatg taataaacta
     1021 catgttttcg attactcatt tatgatagaa tggatttaaa gatttgtcaa ggagggaaaa
     1081 ctgatggcaa gaaaaaatac acttcgatat attttgttag ggttattaag taagaagaag
     1141 atgacaggat atgaattgaa tcaatcgttc aaaaatgaaa taggagaatt ttggcaagca
     1201 aaacatagtc agatttatcc tgaacttgca aaaatggaag agcaaggaat cattcagcat
     1261 caagtagaga tcacaggtga aaaattggaa aagaaagttt atgaattaac agaagaaggg
     1321 aaggaacaat tggcagagtg gattcataca cccaccaatg aactaccggt taatcgagac
     1381 gaatttgttc tgaaattgta tttcgtcaaa gacgtgaatg atccggcatt agtagaaatt
     1441 attcagcagc agcgtgacct tcatgaagaa aaacgacttc atctattaga gcgaaaaaaa
     1501 acgatctttc ctactgaaaa agaaaaacat gaaaattacg gacactacct gattttagcg
     1561 catgcgatca atcgggaaac agaatatgca aattggctaa cagatgtatt agaagaaagt
     1621 aaccgaaaaa aataaaaaaa tatccgaaca gtgatggaga attcctttct atatgaaaga
     1681 aacgcagatc accgttcgga tattcttatg ttcaaacagg ccttttttca agtatttatg
     1741 tagcatctac ttattaaaaa gcttggtact taggagatta gtggcgttta gagttctttt
     1801 aacaactgtt cgtagtcagc tttttcatcg acaggaagga gcttgtaagt taattcgtct
     1861 gtctcgttgt catgaatgat gtacatctta gcattctctt ctttgaagtt accgatttgt
     1921 aaaatcgtat agcgttcgtc gatcaattcg atatctttga ttgcttttga aaaaacttta
     1981 cggacatggt gcattttctt ttggcggatt tctgcctttt ctgcagcttt tgacaaagta
     2041 aatccgtcat ctaaatattt tttgatcagt tctactttta tgactgtagg taaacgatat
     2101 tttctaggac aattcgcatc agcttcgatc gaacgaatga atcccttttg ttcccaatac
     2161 cttaattgac gtggagacac acctacgata tcacttaatt cactgatgcc aacaaccaat
     2221 tgatcatttt ccaacaaacg tttaagggaa gccccaacca tttttgtcac tccttttgtc
     2281 ctcttgcttc ccttaattat atccgtatta acttatgtgt caagtaggtt gacaaatagc
     2341 gaatttagga ctaaagtatt ctagtagttt cagaaaaaat tcagaaagaa ggagaaatat
     2401 gagtaacaac caacccgtag atatttacgg aaaaccatat aatcggacac ttttagttgt
     2461 tgtcttatta attggtacat tttgtaccgt tttgaatcag accttattga cgacagcttt
     2521 tcctacattg atgaaagctt tcgatatttc agcgtctgat gtgcaatggt taacgactgg
     2581 tttcttgcta gtcaacggga tcatgatccc aataacagca tggctgatca ataaattcag
     2641 ttcaagaaat ttatatcttt ctgccatgac gatctttttg atcggaacga ttacttgctt
     2701 tacagcacct aattttagta cattactaat cggtcgtttg atccaagctt gcggtgtggg
     2761 agtatcgatg ccattattgc aaaatatcat gctatctatt ttcccgccag aaaaaagagg
     2821 atcagcaatg gggatgtcag ggatcgttat tggacttgct cctgctttag gccctacatt
     2881 atctggttat atcattgata actaccattg gcgtgacttg tttggtatgg tactgccaat
     2941 cgttgttctt gtcttggttt tagcattctt cctaatgaaa agtgttattc cattgtcaaa
     3001 tcctagcatt gatattttat ccgctatttt atcaacgatt ggattcggta gtttacttta
     3061 cggattttct agtgtaggag atgacggctg gggaagcttg aaagtaattg gtttcttagt
     3121 tgttggtgtg attttcatcg ccttgttctc atggcgtcaa ttacatttgg aacatccatt
     3181 cttggaactt cgtgtattca aatcatctac attcacgatt gcagctgttt tagctggtgt
     3241 aacaaatatg gcgatggtag gggcagaaat ggtcgtacca ttgtatattc aaaatattcg
     3301 tggagaatca gcattccatt ctggcttgat gttgttgccg ggtgcattga tcatgggggc
     3361 tatgatgcct gtgacgggtg cgattttcga taaatacggc gcgaaacgtt tagccatcac
     3421 agggatgttc attttgacag cggcaactgc accatttgct ttcttgacaa aaacgactcc
     3481 agttttatat atcgtgatcc tttatgcgat ccgtatgttt gggatctcca tggtcatgat
     3541 gccggtaacg acttctggta tgaatgcatt gccaaataac ttgatcagtc atgggacagc
     3601 ggtaaataat acattccgtc aaatcgcaag ctcgattggt acagctattt tgatcagtgt
     3661 gttgacgaat gtgacaaaag caaatatccc aagcaaatct gtattggata atacgccatt
     3721 agcttataaa gatcaggcaa tcaatgccac actgtcaggt taccatgccg cgtttatcgt
     3781 agcgatcatc tttgggattc ttggctttat tattgccttt ttattgaaga aaaaagaacc
     3841 tgttctaatg aaagcggggg ataatgcatg attattggag ttttgattgt cagcttgctt
     3901 gcttttgctt taacgaacgt gttcgctaaa aaaacatggc aaaccttttt atctttgatt
     3961 ttcggactaa tcttcgtcgc ttcactaagt ttgatcgtcg ctaatttgtc caatcacttt
     4021 ggaatggaaa aagtaacgga aacaaaaaca gaaaaaattg tttccagtgc tgattcccaa
     4081 ggagcagata tgcttttgta taaagcttta gggaatggaa aagaaaaagt gtatctttac
     4141 cgaacaaatg aaaaacaaga aaaaccaaaa gcaactggta cggataacga aacaaataaa
     4201 gtagaaaaga cagacggcga tgctgaaaaa gtgacgaaaa ctacttattg ggaatacaaa
     4261 aacgacatgt ataaattctg gttcaatatt gctgataaca atcacgaata tgacagccga
     4321 gtgaatacat tcaaaatccc agagacatgg gtagaattaa gtacggacca agcagccaag
     4381 ttagctgaat tagtgaagaa acagcaaagt acgatggaaa gtgaagcaaa agcttatgtt
     4441 caagacggta tggtaaaagc aatgactgaa aatccaaaaa tgagcaaagc agagcaagaa
     4501 caacgtacga aagccttagc tgctgaattc caacaacaag cattcgcaaa attagtgaaa
     4561 gaagcaaaag gcgaataata ttttgaacac catgtaggag gttgtgaaaa agctgctctg
     4621 catcaagcag taagaacaat cagataaaaa tagcactcca tatttttcat ctgattgggc
     4681 ttagtgccgt agatgcaagc ttttgaacac cgtttaagga agaggttgtg agcctgccgt
     4741 ttaactctga gtcacaagga gcaatttcaa aaaacagctt ctcatgtttg ttgactattg
     4801 tgacttgtga ccgaggagtt ggcaggagaa caccgtttat tcgaaaaaag gaactgcgac
     4861 aagacttttg tcacagttcc ttcttttttt tgctatgcta tactagatgt aaaaaatagg
     4921 agaaataaaa tgagggaaat ttattctttt gaatcaaaaa tctatgcttc cgaagtcggc
     4981 aagggcgggg catatattat ttttccgtat gatataagaa aagaattcgg tgctggaaga
     5041 gttaaagtcc aagcaacttt tgacaatgtg ccgtatgaag gcagtatcgt gaatatgggc
     5101 gtgaaaaatc cagatggttc agtctgctac atccttggac tacgaaaaga tattcgtaaa
     5161 aacatcggaa aagaaatcgg tgatattgta gcagttacag tgaagcaaaa ataaaagagg
     5221 ttgtgacaaa agacgtgtca caacctcttg ataaacggtg ttcaaaagcc agtttctcgg
     5281 tagtaagtca aatttatgca aaaatgtgga aacccatgtt tacaaaattt ttcttactac
     5341 tcgaaacgaa gcggctttat cacaacctct tgataaacgg cgttcaatca gctgtccctc
     5401 ggtattagct caaaaacggc aaaatatgag aagctatttt tccatttttt tctctcatac
     5461 tcaggtcata acgctgattt cacaacctct tctttcataa tggtttttca ccatctttat
     5521 aataaactgg ttctttgata tggaaatcta ttttttccaa ccaatctaaa atcttgtaac
     5581 ctaactcttc tgacatcgga aaagaggcgt tgatttgtgc attggagata tggtcaacat
     5641 ggataccgga agtgatcgta caacttcccg gaacggcagt tttgatgatc acagctattt
     5701 tttcggctaa gacatcgtct ttatggaacc gaccatcgtg gctagggaaa cgtacagttt
     5761 gcatctctgt atcacgagaa aatgtagtga ctgttccgat atgtggtgta tctccgcctg
     5821 ttaaagtgat caataagtct ttaccgatta ctttaacagc agcttggatc gtgaaaccta
     5881 gtttggttac ttcaactatc gtttcttttt ccatattaat caccctgcca acgttttgaa
     5941 tgctcattta caatttcaaa ttgatccaaa agtttcattg tatggtgatt aacaagatct
     6001 tggatcgttt gaggctgatt ataaaaagca ggaattggtg gtatgatttg cacacctagt
     6061 cgtgctaatt tagtcaagtt ttccaagtga atggcattta atggcgtttc acgaggaaca
     6121 atgactaact ttcgttgctc cttcattgtt acatcagcag cacgtgcaat caggttgtcg
     6181 cctaaaccaa cagagatacc tgcgactgtt ttcatacttg ccggtacgat gatcattcca
     6241 tcggtcaaaa atgatccgct ggcgacagca gcacctaaat ctttgtttga ataatggtaa
     6301 tcaaacaggc tttcgaattc agttagtgat aagtcggatt ccagctttaa gttctgtttt
     6361 gcccatggac tgatgattcc gtgtgtttct atcatcggat attcttttag tttcttcact
     6421 aggttgatgg cataaatggt gcctgaagcg ccacttacac caatcacgat ttttttcttc
     6481 cgttgtgcca attgttccat tttccgcact cctttttatg atgtcaaaac agttgcagat
     6541 cattcattat ttcaaatatt tttcccaatc ttctacttct tggaattttg cacgtacaaa
     6601 atgttctttc atatcgaaag gaactgtacc gtcaaagata gtttttgcac ttatcccacg
     6661 gaaacgaata gagccaggat tatattctgg taattctgat gggtccaatg gatggttcct
     6721 cattcctggg atcacgatga tatctttatc tccttggaaa cgagtgttga aagtccaaac
     6781 tacatcgttc atgtcgaaaa tatcaacatc ttcatcgact aaaatgactg tcttcaattc
     6841 tttgaaggct gataaagcaa gaatagctgc ttgacgctga ataccttcat ccgcttcgtt
     6901 ttctttacgg atttgcatga tggtcatcaa tttaccacca cctgcaggag gattgtagac
     6961 atttactact tttcctggaa tagctttatc gaccaaggca agaatacttg cttctgtagg
     7021 aataccggcc atagatacgt gttcttcact gggaccaatc gttgtttgca tgattggatt
     7081 gtcttttcgg tgagtaactg ctttgacttt cactacttgt acagctggat tagcatcccc
     7141 agtatagcca ggaaattctg gcattgcttt tcctgagttc gtgttgatat cttcttgcat
     7201 tgtttcattt ggcatgattt ctgcttcaat gatgaattca gcacgagcaa tacccacttc
     7261 atcgactgct ataccatcaa cgatttgaat aggttcgtta cgcaaagctc ctgcacacca
     7321 tagttcattg tagccaagtg gagtggtagg tggttcgaaa gtcgtgccaa tggcaattgc
     7381 tggatctaaa ccaatattga tagtgatagg cattggttta ttcaaggctt cgaattgttt
     7441 ttggaagtga ccaatgtggc gtccgccagg catgatgtac ataccgatcg tatctttatc
     7501 ttctagaacc atacgatgga tcgttacatc gctcattgtt ttttctggat ctgatcctaa
     7561 gactacaccc attgtgatgt atggaccagc atcttcagga gtatttgtag gtgcaggcaa
     7621 aatgttgcga atatcgaagt ctgcatcggt agctagatga acgacttctt gtgctggagc
     7681 gtctgctttg tctactttca caggtttgat tggattttct acagcgtctt tcaagaaacg
     7741 accaagtgtt cgataatcat ggtgcaaaat ttcacctaca cgtttacgac tagccattgt
     7801 tccgatgttc acacgtgtgc cggggaaacc tttgatattg ttgaaagtca tagctggtcc
     7861 ttcttgagtc ggacgtttta ctgtaccgcc agcaccgata taacggtaaa caccagataa
     7921 ttctgcttca ggatcgattt caatatctgt ttcgtgatat tgacctggaa gtgtttttag
     7981 ttcttcgatg acttttctta aatcatacgg ttgatctgtc atgagagatt cctccttagt
     8041 tgtctttacc tatctatagt aaaaggtgaa aaagaggaaa acaattcaac ttgttcggta
     8101 aagtattcta caatggaatg gatgcgtttt tttgataata gaataaacta tgatatactt
     8161 atcactaaaa gaaagcgcat acttagtgtt ggaggaagga aagtgaaaaa aatggaggag
     8221 tcatttccta aagcagtaaa agtggaaaat atagcgaata ttttgaaagt tacatttgaa
     8281 aacggagaag taaaatacgt gaaatctcat tggacagaag agataaccga tgccttgcaa
     8341 tttggaaaaa aaggaagagg aaaaagaaaa aatcttctcg cactttctcg taatatgtgg
     8401 attgggactg aagtaacgat tgaagcagat ggaacagtat tcataaatgg aaaagacagg
     8461 tatacgccag aagagttgtg gtacaaagga aagaaaagta taccagaatt ataaaaaata
     8521 attaaaaaaa acagcgcgaa acaaggaaca tattacttcc tcgtttcttg ctgttttcta
     8581 ctatttcagc gctcttatga ctcaaatcta aatgtggttg tcacaacctt attctgcacg
     8641 caaagcgata gcggcgtctt ttttcgctgc cattcgtgca ggaagatgac cgccaagcat
     8701 cgtcaatata gtagagacga tcactagaat aatcgcatgg acaggattta gttgagcaac
     8761 attttttaga tccgtcatgt tgtataagat gctattgata gggaacgtag ctagccatgc
     8821 aataaacaca cctaatatcc cagaagaaat acctaaaata cacgtttctg cgtcaaatac
     8881 gcgagtgatg tcttttttac gtgcacctaa agcttttagt acaccgattt cttttgtccg
     8941 ttcaatcaca gatgtataag taatgatact gatcatgatc atacttgtta ctaaagagat
     9001 ccctgcaaaa gcaataagga cataagtgat agcatccatc aatccgccag tcagttcagt
     9061 catcgttcca gctaaatcag tataaatgat tttatcttca tctgatttgc ctttattgta
     9121 atcatctaga taatccaaga tcttttcttt gtcttcaaaa ttgttcggat aaatcatgat
     9181 acttgaaggc aagctgtctc cacctaaata actaagcaat gtttgtttgg cattttcgtc
     9241 aactttttca gtagttaaga catttacacc actgtctctt tgagctttga cgatttctga
     9301 ttctttgttt tcgttgacga tttgagtcgt taattgatcg ctataagcga ttcctggaga
     9361 taagagattc attgtagaag aagatttcac gcgtaggatc cccgagatct tcaattcatc
     9421 agaagcattc tgatacatcg catcataatc tgtattaggg ataaaattcc cagttggaag
     9481 ttttgtatag taagtattgt tgtttactaa tttgaatgtt gtaccaacga tatcatcaaa
     9541 atcaagtttt tcgtcttctt tcacatcaaa tccaagattc ttcaatgcgt tgatattagt
     9601 attattattg ccgtctacga tcagcacgac atctgttgct gaggctggat aacttccggc
     9661 aagtaaagaa taattgtctt ttaaaaagtt ttctttgcta gtgtcaagct gtgtagggaa
     9721 acttgacact cccacacctg tcattgctga catcgtacta gataaagaaa gagattccgt
     9781 atcaggattt tgattcgaga agctgacagg ctgtactttg ccatttacat cacgtaaaag
     9841 attgattcct gtagtacggg taaatccgat attattactt aagttaggat cgatgtctgt
     9901 tacgtaatcg acgtatgttt gatcaatctt attcgtgtgc tgtgctttat cttcttcgct
     9961 gacttttgca gtaatcgttt tgctgtctgg ataatccgct ttgcttgcac ccaatccggc
    10021 atcgtcacga gtctggttag tcgttacctt agaaatagta atcggaaatt tcgccatcgt
    10081 ttcagcttgc gtgttatcga tttgtttttg gaatccagaa gaaagggaca gaacgatcgc
    10141 gattccgatg atcccaatac tggaagcaaa ggaggtcaag aaagtacgtc ctttttttgt
    10201 tcggatattg ttgaaggaaa gctttaacgc tgtccaaaaa ctcatctttg ttctgcgtaa
    10261 gttaaattga tcatcttttg gtcgttcgat gtgaggatgg gaatctgtta agatcttacc
    10321 atcagaaaat tcaatgattc gatctgcgta ttgatgggcc agttcaggat tatgtgtgac
    10381 catgatcact aatttttctt tcgataactc ttggatcaat tccatgatct ggatacttgt
    10441 ttctgtatct aacgctccgg ttggttcatc gcacaaaagg atatctgggt cattggctag
    10501 tgctcgagcg atggccactc gctgcatttg tccaccagat aactgatttg gctttttatg
    10561 catatgattt gtcaagccga ctcggtgcaa tgcatcttct gcccgttttc gtttttcgtc
    10621 tttagaaaca ccacttaatg tcatcccaag ttcaacgttt tcaataatgc ctagatgacc
    10681 aatcaagttg taactttgaa aaatgaaacc gatagagttg tttcggtagg catcccagtc
    10741 actgtcctta aagtctttag tagactttcc gttgattacc atatcaccgg aatcataatt
    10801 atctagtcca ccaatcacat tcagcatagt cgttttacca gaaccactag gacctaaaat
    10861 cgctacgaat tctttttgtc tgaaagcgac agacacacca tccaatgctt tggtggtggt
    10921 ttcgccgact ttataatatt tttttatatc ttttaattga agcataatca cccttctccc
    10981 gtattgaaat attcggtata ctaataagta tatcagaaca atgatcgtag tatacgaaat
    11041 aaatgttaac tgaagatgaa ctacaagaaa aaatctagaa atttttcaaa aaacagaggg
    11101 agatcaatga atcgtatttt agtagtagaa gatgatccgc aattacagtt gctttaccgt
    11161 tctgtgttgg aacgagcggg cttttcagtc atcaccgcat tgaatggaga ggatgcgctg
    11221 aaaaaactag aagcgacacg tatagaatta atcattacag atatcatgat gccgaaaatg
    11281 gatggctatg acttgctaga ctcattacgt agcaccagat ttgacacacc tgttctaatg
    11341 attacggcaa aggccgattt tgaggataag aaacgcgggt tcaaattagg agcagatgat
    11401 tatatgacaa aacccatcga tgtcaatgag atgatcctac gtgtggaagc attgcttcga
    11461 cgttcaaaga tcaattacag cagtagcttg ataatcggac aaacaaaatt agagctagat
    11521 gcttatacag tgttacaaga tcagcattcg ttgattctgc ctcaaaaaga atttctgctt
    11581 ctgtataaat tactgtctta tcccaacaag atcttcactc gccaacagtt gatggatgat
    11641 atttggggat tagatacgaa tacagaagaa cgaacgatcg atgtacatat caaacgttta
    11701 aggacccgtt ttgaaaagac ggaagatttt caaatcatca cagtacgggg actaggctat
    11761 aaggcggtta tttaaagatg aaaaaaaagc tattttcaca attatggatc tattttgcta
    11821 gtattgtctt catttcgatc ttagtgacac tgctgtgttt tctcggtttt attttcttat
    11881 tgtctcgaca ttctatctcg cctgctgaat cggctggaaa accaacgtta tacccgttat
    11941 tcgtctttgc ggggttcagt atggtcgtgg gtacaggaat atcgattttt gttgggcggc
    12001 gtatcctgca tccaatcagt gcgctaggga caaatatgag tctggtagca acgggagatt
    12061 tttcgattcg aatggatgaa cagcagaaag tagcagaagt acagcaactg tataaagatt
    12121 tcaacgttat ggtccaagaa ctcaatagta tcgagacact gaggaatgac tttgtgtcca
    12181 gtgtatccca tgaattcaaa acaccactag caacaatcca aggatatgtt caattgttac
    12241 aagccccaaa tctctctgac gaagaacgcc aaatattttt atatcggatt atcgaaagta
    12301 tcacgcagct ttcacaatta acagagaaca tcttaaaatt gaacaaactg gaaaaccagc
    12361 gtatccaact ggaaaagaaa gagtatcgat tagatgaaca aatcagagaa gtaatcgttt
    12421 tttttcagcc taaatgggag aaagaacagc tagaattgga tatcgaactt gctgcagtaa
    12481 attacacagg caatgaagag tttttgtacc aagtgtggct gaatatcatg gataacgcca
    12541 taaagtacaa tcaaatcaat ggacagattc atatcaaact atttgagaca gccacagaga
    12601 ttgtactgga agtgaccgat tcaggtgtag gaatgaatga agagaccaga gatcgaatgt
    12661 ttgaaaaatt ttatcaagga gatacaagtc gtcaaatttc tgggaatggg ctaggacttt
    12721 cactggttaa aaaaattcta gaactgcatg atggacgtat tgattatagc agtatcgaag
    12781 gagtaggaac gacagcaatg atacggttaa gtaaacaata ggaaaaagaa taaaacccct
    12841 aaaaattcta ttgaaggttt ttaggggttt ttagtcgttt ttttgtgatt agggaaatgt
    12901 tcttacggtt cttttggcat aaaaatcgct gctttcttat tgaactacga gaaatgttag
    12961 aggtgtcatt gaaacaagga catgatgcaa gaaagagagc gaaagtcatg cgtcgctctc
    13021 tttttttggg tggatagatg gacagaaaat gtagggctta gttttcttct tgatttaaat
    13081 actcccaaaa tgtatctgaa gccaaagaat gctcaccgac tttacgagta aatgcaagat
    13141 aactctctgt tgttggagaa atagggagaa tcacagtatt ttcttttaat agattcttga
    13201 ctgttttttc cataacaata gcaatcccca tgtcatttgc aatcatattg atgatcaagt
    13261 cgattcttgc tcctttataa gagatttttg gttcaaatcc agcttcgcga cacagatcta
    13321 gtacaggttg atacaagttc gtagtggggc caaggagcaa aaagttctcc tttttcagtt
    13381 cgcttagatc caatttcttt ttactagcta aaggatgatt tttaggtaga actgctacaa
    13441 aatcgtctgt ttcagtaggc aaccactcaa tcgaacttgg tggggcctgg aaacttctag
    13501 caaagtggat cgtgtcacta tgttcattgg cgtcattgta agttaattcg acactttcca
    13561 cttctttcaa ctggactgta aattcaggat ggcgtttcaa aaactcggtg attttggaaa
    13621 aacctttata attgatcatt gtcggtatcg ttaagatatt taatgaaaga ttgttgtctt
    13681 tcgtataggt ttcaagcact tcttgcatag catggtattg ttctacgaca ttttttacat
    13741 atgggagcaa taagcttcca gcttcggtca attcgatttt tctatgggcg cgttcgaata
    13801 atttgacgtc taattctgtt tctaacgaaa gaatctgttt agaaatattt ccttgggtgg
    13861 tgaattgtcg atcagcagtt ttggtgaaat tcattgtttc ggctaaatca agaaaaactt
    13921 cgaatttatg gatatccatc atattcctcc tacttattcc aataaagaat actttaacac
    13981 aaaaaatgaa ttggtgtaat cttctctgtc tgttacaatc tttcttgcag cgaaagcaat
    14041 aattacagaa atttttctga tttttttcgc ttcgtagaaa aagagaggag ttttttgatg
    14101 ccaactggag ttttgatcaa tgtaggttcc gttttgtttg gcggactaat tggcggatta
    14161 gtaggaaata aattaagtga acattttaaa gcacagctga cgatggtttt tggtgtgtgt
    14221 tcgatgggga tgggaatcta ttccattgcg ccgatgaaaa atatgccggc tgttattttt
    14281 gctttagtga taggaacagc gattggtttg attgttcatt taggtaatgg gataaataag
    14341 ggggctgcgc tgatgcaagt acctatttct aaaatcttcc ctagtgaaaa gcttggtatg
    14401 acccacgatg aatttatcag cacattagtg acggtcattg ttctattttg tgcaagtggt
    14461 acggggatct atggaagttt agattctggg atgacaggag acagtacgat tttgatttct
    14521 aaatctgtcc ttgatttttt cacagcagct atttttgcgt gtaatttagg gtatgtcgtt
    14581 tctgtgatag caattcccca attcattatt ttttatattt tgttcttatt ggcaaaattt
    14641 atttatccat tgactacacc agacatgatc ttagatttta aagcttgcgg cggattcttg
    14701 atggtcgcta ccggttttag aatgatcaac gtgaaaatgt tcccagtagc tgacatgata
    14761 cctgcaatga tcgttatcat gccactgagc tggatgtgga caaattggat tatgccactg
    14821 ttataataaa aatcaaagag aagccatttt ttgctgacta aaaaggatca aatcttttag
    14881 tcagtttttt tgtatttgac aaactgattt tgaaactata ttatatgttg tataatatag
    14941 attgaaataa aatattacac ttgagaatag aaggtgacgt aatgcacatc cagattccaa
    15001 ctgttcttct tgatggtact gtgctagcag cattaagcaa ggaagatatg tatgggtatg
    15061 ccttaacaaa aatcgtacaa gaaagtctct ctgtcagtga atctacacta tatccggttt
    15121 tgagaagatt gaaaaaagaa ggatatcttg agacctatga tgaacctttt gaaggcagaa
    15181 accgtcgata ttactcgttg acaccaatgg gaagtcgtca tttagaagaa attattgatg
    15241 aatggattgt ttttcgagat tctttagacc ggttattgga ggagagcaca aatgaatgaa
    15301 tatttgaatg aagttgtgga tcatcttcaa gaaattcctg aagacgatcg ttttgatttg
    15361 atccagtatt atgaggaata ttttttagat tctggaaaaa cattagatca gatcattgat
    15421 gaatatggta caccaaagca gtttgcctta aaattaaaaa tcagttactt ttcagaagaa
    15481 gaacaagcag aaaacgagtt agtgaaaaat ccaaaaagac aaattcgcct gatttggtta
    15541 atcattatcg gtttatttgc ttctcctgtc ctcattccac tagcactggg gtttatattg
    15601 gttattgggg gactattggt tgctttacta gcgctcattt ttagtatcta tgttttatgt
    15661 atcagtatct taggtgttgg cctattcatg atcatctcag gaatcagtgt gtttggacaa
    15721 tcgattctga gtggattatt ctttatcggt gtcggtctgt tcgccacagg aagcgcagta
    15781 tttatttcgc cactgttgct gaaaggaaca aaagggcttt tttatgtcat gatgaacttt
    15841 gttaaatgga tgggacgacg ttttattaca aaaagagatc tgcattcagc gggcgtttga
    15901 aggaggacac ataaattgag attgaaacat tttttgatta ccggtattgg tctgatgctt
    15961 actggtggcc tcctagcagg tgcaacttat acattaggcg ctcaaaagag tctgacttgg
    16021 gataatggtc ctcggttgat cgatatggtt actgagacaa aaaaaatcaa ggatgcaaac
    16081 aaaatcgtca tccatgcaga aaatcaaaca gtttcggtca tacgcggatt ggattttgag
    16141 ataaaaacga cttatgataa gacagaaaag ccagaaataa aggagaaaaa tggcgtgttg
    16201 actgtgaatg cagtcaaaaa atcaacaggt gcaatcatta gtttagaaga cacaagtgca
    16261 caaatcacta ttgttgtccc tgcagatcat gaattatctg aattgacaat cgaagggaat
    16321 aatagtgcaa ttgatatcaa cgaagtatca atcaaaaaag tgaatactaa gacacatgat
    16381 ggctgggtat cgttcaatga atttacagga ggaacaataa ctgcgaaaga tgaattaggc
    16441 tcacttcgat tagatgaggc caatgtggat aacttgatcg tcacaggtga aaacagcaac
    16501 ttccatctag aagacagttt gatcagcaaa gaaggaaaag tcatcctaaa cggtggcaat
    16561 ttatctttgc atgagatgga aaacagtggc tatactatcc aaacgtctgg tgaatcttat
    16621 attgaaaaag actaccagcc aataacaaat actttgttag aacaaggaca gaaaaagcta
    16681 aagatcactg ctaaagacac atcgatcaat attacgacgg atcaagagga caatgaaaca
    16741 gattgatcct gtactcaact ggatatttta agaaaaaaca gcaaagatcc ttccaatctt
    16801 tgctgttttt catcgcttaa cgcacataac tatagtaaaa taagaaagaa aatatctaaa
    16861 aagaaaacag ggtgaaagag tatatgaagg tagaagaagg tcaaagagaa aagttaaaaa
    16921 cagaaatgga aagattacat acttatatca ctcaactaag ccaaaccttc tatgatccag
    16981 acaaagaaaa agtgatggtt aattacccga acaattcaga aggtcgccaa ttagagcaag
    17041 tgtaccatga agttttcaaa catttattga cggtgaagaa agagctggat tattattctt
    17101 taccgattat cgatacagga atattgaagt atgatgggaa gaaggaacga tttatcttta
    17161 aatctgttcg ggaagatttg cctctttcag cagggatgga tctagaggtc ttggtagaag
    17221 actattttac agaagaaaag cactgggttc gaacaaaatt ggattattta ccgcaggcag
    17281 ccggagggac acaggcaagc ggttggtaca tcactgaaga caaagagtta gaactagaag
    17341 gtgtaatggc gcgtattcga aaaaaaaatt aaaaaagtaa cattagatat ttattgaagg
    17401 ataaaggagc gcaggaagta gcatgagaga aaaaagagca ttttatatca atggttatgc
    17461 agggattgtc ggattggtcg tattagcttt agttggattg tttttcttct atttaggtat
    17521 gtggcaagcg aaagtttggg cacttttttt aagtattttt ctttggttga tcacgttatt
    17581 gttgttaagt tcggcaactg tagtcagtcc taatcaagca aaagtaattt tgttttttgg
    17641 acaatattta ggtacgattc gagaaaatgg ctttttcctt acgatacctt tggcacaaaa
    17701 aatgactgtt tcgttgaaag ttcggaattt caatagttct gttttaaaag tcaatgattt
    17761 ggatggaaac cccatcgaaa tctcagcagt agtagtcttt aaagtcgttg atacagcaaa
    17821 ggcattattc gatgtagcgt attatcaaga ttttgtagaa atccaaagtg agacagccat
    17881 tcggcatatc gctagccaat acccgtatga tacattcaat gagaatgatt tgacgcttcg
    17941 aggaaacacg acggcagtgt ctgacgagtt gcaaaaagag ctgcaagagc gtttagcagt
    18001 agcaggtgtc gaagtaatcg aaacacgctt gaaccattta gcctatgcaa cagaaatcgc
    18061 tagtgccatg ctccaacgtc aacaagcaaa agccattttg tctgctcgac aaaccattgt
    18121 tgaaggagct gtcacaatca ctcaaatggc cttagagcaa atcgaagatg gacaagaaat
    18181 caatttcacc gatgatcgga aagtccaatt gatcaataat ttacttgtct caatcattac
    18241 agacaaagga acgcaacctg ttatcaatac aggcgacatg aaagaccgta agtgacatac
    18301 tttttgtaag ataggaagaa ggagtttagg acggattatt gtcttgaact ctttttttag
    18361 ttgttttaaa gaaaatgaca aaattgaaag aagaatgata gttgattcga aggcagaatt
    18421 gttcgctttt ttctataatc agtatataaa gtaagagaga aggggaaaaa gtgaaaaaac
    18481 ttctgatcgg tctacttgtt ttcatcgttg tggtacttgc aggggtgaaa atcgcagatt
    18541 acgtagttat gggtggagaa gaatactatg tacaaattac gacagatggt acaaaaacag
    18601 tttcaaaatc agactctgga caagaaacag tcaactatag atatatcctg cctggctata
    18661 cgaaagaggg taaggaaaaa gaactggact tcaagggaca attgactcga ccgcttcgta
    18721 aaggagcata tttaaaaatc acctggaaca aaaataaagg tgtcacttcg tatgaagaag
    18781 tcgaaaaaaa agacgtgccg aaaacagcac tggaaaaact aattaaaggg tagggaaaga
    18841 aatgaacaaa atagtcgaag tacagaatgt aacaaaagta tacggaaaaa acaatgagaa
    18901 aaagacgcaa gcattaagcg gcatcagctt cgatgtagaa aaaggcgaat ttattgggat
    18961 catgggcgct tctggttctg gtaagtcgac acttttgaat attttatcca cattagataa
    19021 accaacagat gggcatatcc gaatcaatca aaaagatgtg accacattaa aaggaaatca
    19081 actagcagat tttcgtgcga atgagattgg ctttattttc caagatttca atttattaga
    19141 aagcttgaca gcacaagaaa atatcgctgt tcctctttct ttacaaggcg tcagaccaaa
    19201 agaaatcaag caacgtgtcc aaaaaattgc agaacgttta tccatctctc atattttgga
    19261 aagctatcct tctgagattt ccggtggaca aaaacaacgg gtcgccgccg cacgtgcatt
    19321 gatcacacaa ccaacgattc tattagggga tgagcctaca ggtgcgctgg attccaaaag
    19381 tgcccgggat cttttagata cgatggacga attgaataca aaagatcatg tatcgattct
    19441 tcttgtgacg catgatccgt tttctgcaag ttattgccaa cgtattttat tcatcaagga
    19501 tggcggtatc catcaagaag tgaaacgtgg agatcaaagc cgtgattcct tctatcgaga
    19561 aatactatct attcttggaa acttggaaca gtagggggag attgactatg ctttggaaat
    19621 tatcacttac tgggatcaag agccgtttaa gagactactt ggtgttattc tcaggattag
    19681 ttatggcatc tgctattttt tacatgtttg aatcaatggc aagcaacgaa gcttttttga
    19741 aaagtaatac gatcgttgcg gctacagtta tcattttccg attcggttct gttttactag
    19801 ggatcatcac attcgtttat attttatatg caaattcctt tttgatgacg atgcggcaaa
    19861 aagactatgc aatgtttatg atgctgggag caaaaggcag aaaaatcgca cagatgattt
    19921 tttctgaaac attcttagta gggatcgcag ctactttagt gggttcagct gtcggtgtag
    19981 gattgacaag tatcgtccac cgattattag tggatcagtt agatctcaat atttcgcatt
    20041 ttacaccttt tagtattcac gggttgttga tcactgtttt gttttttgct gttttgtttt
    20101 tattagctgc tgttgtcaat gctttttcga ttgtcaaaaa accgatttta gcattgattc
    20161 gtgcggatca gacaccaaca agaatcaagc agcataaatt cttgtttttc cttgaagtag
    20221 tactgggaat tgcttttcta ggctgcggtt actatatgat gaaacacgtg gggacctatc
    20281 aagtctttgg tataggggta gccttagtta cgatcgtatt aggaacttat ttcattttcc
    20341 attctgtgat cattttcttt ttatcattac taaagaaatc agaacagatt tcattgaaaa
    20401 aattgaacaa tttcacattg tcacagttaa actttcgtat tcgtgaatat acacaaatgc
    20461 tctcaatggt cgctatgctg tttgccttgg cactgggcgc tttgacggta ggattaggtt
    20521 ttaaaaatga aattgcagac ttgacagaaa acaattctgg atatgatcta gtgatgaata
    20581 atcctcgggc agaagatcag caaaaaatca aagaactttc accaacactt tctgcttctt
    20641 atactcaaaa agaagatgcg ggaacgattt actataatgc aagtgaattt gcggctcaac
    20701 cattgatcat gataaaacat gaagatggaa caccgccgaa gatcacgaaa gaaaaagttc
    20761 ctgctaaaaa aatgaatgaa ctgactgtac aagaggaact tcgaagctat gaattgccgg
    20821 aacagcaaga aaaagaaatc aaggtagtca gtcaatcaga atttgatcaa ctgaacttgc
    20881 cacaatccac tttacagcta gttcaggtaa aagacttcca agcaaacctg aaaccaatcg
    20941 aaacacttgt tgctcaaaat aaaatgaaca atccatcttt gcaaaaagta gagtacagca
    21001 accagaaata tgaaatgtat gaagtgtata atggtctatt ctctggtttt gaatttatgg
    21061 gattcttcct aggtttagct ttcttgacca tgcttgctag ctgtttgatg ttcaagatct
    21121 tgtcaggaag caagagtgac attgctcgtt atgaaatgct tgaaaagata ggaacacgac
    21181 gcgggttgct taaacaatcg atccgtagag aagtaggcgt gttattctta gcaccaggaa
    21241 tcttaggtgt agtccatgtc ttattcggat tacaaatgtt tggtctattc atgcaaaatc
    21301 catacaaaga tatttgggtt ccgtttacga tattcttcgt attgtatttc atctactatg
    21361 tactgacgac atggttatat actggaatcg tattgaaaaa gagattgtga aaaagctgtc
    21421 ctgcatcaag taataagaac agccaagcaa aaatagctcc tcatattttt cgtttggttg
    21481 ggcttattac cgcagatgca agcttttgaa caccgtttgt tcggaaaaag aggttgtgac
    21541 aatatttttg tcacaacctt tttttcacgg tcttttatta gaatatagta aattttttct
    21601 cgttactcac ggaataagct gttaagaaaa cggtttccat gtatactgga atcagtgcaa
    21661 atgaaagaaa agagggtgca aggaacatgg aaatcaatga acaaaatttt ggcgaaaact
    21721 atcacttgat tacgatcacg aatcaaaatg ggacatcttt gtctgtcagt gatcttgggg
    21781 cacgggttgt tcattttcaa acaataatcg ataatgaaaa acgagagttg atcttaggtt
    21841 ttgatgaagc aaaagaatat ctagaaaaag acccttatat cggtgcttca atcggacgta
    21901 tggctggacg gattacgaat ggcacattca aattagatga tgaaacgttc gaagtaaaaa
    21961 cagacccgga cactggtcat tgtttacatg gtggtgcacc tagctttgaa gccaagcagt
    22021 ggcattatac agtcatcaat ggtgaaaacg aagcatcggt cattttctat cagactagcc
    22081 cagatatgga aaacggattt cctggaactt tagatgtaga agtacggtat acgctgacga
    22141 acgatgatac atggcgagtg acggtccaag ggatcagtga ccgcaaaaca gtattcaatc
    22201 ctacaaatca tgtctatttc aatttaaccg gtgatccagc acagtcaatc gacgaacata
    22261 tactttggtt gaatagccga ttatttgcta cgctcaataa agatacaacg cctacaggag
    22321 aagtagtttc agtaagtggc acagcatttg acttccaacg tcctaaaaaa ttaggtgagg
    22381 tctttgccag tgattttcgc caatcaatga tagtgggcgg catcgatcat ccatttttgt
    22441 tgaaaaaaca atctggttta ctaaatgctg cggaattgac aagcccagat gaaaaagtat
    22501 cgatccaagt aaaaacagat gcttcaggaa tcgtgatttt tacagcaaat tttggagaag
    22561 atggaccgga aatgcgcggg aataaattag taaatcatgg cggtatcaca tttgagactc
    22621 aagaactgcc aggagcggag cgacttgaaa gttttggaga tgtcactctg gaacctaacc
    22681 aagtacgcga gtttgtaacg gaatacaaaa taaatataaa gaaatagaat aaattaaaaa
    22741 gggagtgtga cagtgtcaca tccccttttt aatttattct atttctttaa aggcagatca
    22801 agccagaatg atttgtctaa acttaacaag gttagtacag gaacagttgc agctttaact
    22861 gtacgagtag ttgtttctgg tatctgtctt gccgtaaaat tgttccacaa atcccagatt
    22921 gaagcgacac ggaagatgga agaagcgttg ttgacgcgtt ttatcgttga aaattctaat
    22981 cctgtgattg gcacgccatc tgttgtccat ttgattggca catcgaatcg cttagacata
    23041 ttgaggattt cagcgtttgc ttcttcagtt gttgctgctt cttttttcgg ttcatcatat
    23101 tttgtcaggt cgtacgcttc gatgatcgcg ttcaattttt gtgaatattg gcgatctgta
    23161 gcataacgtc cttccaaata tttggttgct tctttgtagt cttttgtttc cgacttccaa
    23221 gttggtttgt agaaatcagg attgccagtc agtccatttt tgatcaagtc ggcatagtct
    23281 tccaaacttt ccttgtaaga aggatattta cggaattgtg cgcggatttg gtagctttgt
    23341 ccggaactat cttgttcaag tgtattgaag gtcacgctgc ttcctttata tgatcctttg
    23401 ataccaaaaa ggttatgatt tggttcgctt gataataagc tgtttccaga tccactttca
    23461 aggatagctt gagccatcat gactgatgcg tagattcctt ctttttgccc gatttcctgt
    23521 gcatcatctg caatcttttt caagaactga tcagttgttt ggttttgact gaaatggaac
    23581 gagccatcta atccatctaa aatagatgag ccgcctgtca gcgaacctga agcagcaggt
    23641 aaacctgcta agtttactcg gacagcaaaa tcaggcgtga aatctgaaat agaagttact
    23701 cgaactttat ctcctggttg aggcgcatgg ataaattgtc cgttcccaat atagatacct
    23761 acatggtgag taacaccgga agaaggtccc cagaagacga ggtcgccagg ttgggcctga
    23821 cttactggaa tctgcgtacc tgcatattgc tgttcgcctg tccagccacc gatataatga
    23881 ccggttgctt tcatatatac gtaataagtc aaaccagaac agtcaaaagt atttggacct
    23941 tttgctcccc atacatatgg ttttccaaga tgcttgaatg cttctcgaac gattgcttgt
    24001 tggacattcg ttgtatttgt aggcaataca gcatcaattg gtgattttac aacaaaatca
    24061 gaagaagcag aagatggatt ctctataccg ctttgatttg ctgtatttgg acgagatgaa
    24121 gcattgttcg ttccgccatt cgatgaacca ttgtttggat ggtttggttc tctctgagta
    24181 tttccattgt tattcgatcc agatgggttt gtttgattcg aagaattccc gctgttcgaa
    24241 ttattgttat tattgtttga attatttgaa ccattattat tgttgttatt acccacatct
    24301 ggtttgtttg gcgtttccgg atctggtgta ctagggactt cttcactagg atcagttggt
    24361 ttctctgttg aagtatccgg tccagcttta aattctgcag taatagataa attgttcgta
    24421 cctactgtaa aggtctttgc atcataattt acttctttgg caccattaac agcgactgaa
    24481 gcaatttgtt caccttcagc tggcgtaata gtgtaagtta ccttcgtttc cgctaataaa
    24541 ccttctaccg ttccactttc cgtaatatcc aaaggttgct gttcagggga atccgctgtc
    24601 gaagcagtca gttggatctt accaatcaaa gaaggagcaa ttgtaaggga atatgtctcg
    24661 gctggctttt cattttctga tggatcagcc ggatcaattt cagttggctc ggtcgatcct
    24721 gttgttgagt tagttgttcc agttgggtct tctgtaaaag aatccgttgt ttcactagta
    24781 gctgagctgg atgtagtcgt atctgttgtg actgtttgat cagctatttg attatctacg
    24841 gcaaatacgg tattggtcga caaaacagac ggagcaatca gccaagtagc agctagcaaa
    24901 cgtatcgttt ttttattttt cataataaac tagtcctttt cctttcattg attttctgtc
    24961 ttattcagca ttcattagac attttttgga acagataatc gtgtcgaaaa gctttttctt
    25021 ttcataaatc tgtctgtgta ttctaaataa aacaatttgt aaataagcaa cgagcattca
    25081 ttcgtttttc tttgacgttc attttattgc atagaccacc tttgtttggg gataaacaag
    25141 tggggataaa aatggttatg catatgtaaa ttataccaaa gtttggaaag tatcacaaaa
    25201 atttataaaa ataatgatcc taaaaagaaa aagactgaaa tatgtgataa acatctcata
    25261 cttcagtctt tttcattaac tattcataag acattaggtc ttcatcaaac ccgctaacga
    25321 gagtagtgat cattgctacg actagactaa cagccagtcc tgctaagtac cagaaaaaag
    25381 taccggaaat gaatgcaggc aatgtggtca gactaccaaa tacaaaagcg atcgctttca
    25441 cttgggcaaa tcccattaca gctccaccag cagctgcacc aatgcaagca gcaacaaatg
    25501 gttttttcaa tgggatcgca attccgtaaa cagttggttc ggtcactccc gcaagtaaaa
    25561 tcgaagcaaa agcagaaccg gagatcgaac gggtttttga acgtttactt cgcagaaata
    25621 cacctaaagc tgcaccagcc attccaaaat tggctgctcc tgtcaacgga acgattcggt
    25681 cgaacccata agcagagata ttactgatca tgacagggtt tacagcccat tggataccaa
    25741 atattaccaa aatattccaa ccaccagcga tgattgcgcc actgatcggt ccgttaatat
    25801 ccatcatcca agtaattgcg gcagctaaac cttcgccaag gtaaacaccc gcaggcccga
    25861 ataccattaa cgtcaaagga accgtgataa ctaatgaaag taaaggtaca aatactaatt
    25921 gcatattttc gcgaatatat tttttgagga atttttcaac aaaagaataa aagaaaatac
    25981 ctaaaatcgc cggcatgaca gtagacgtat actgcatcag tactacagga atccccagaa
    26041 aatcagtagc tgctttgcta ctgtctgaaa gtaaagaggt cagattcggt tcaatcagtg
    26101 ctgcagcaat gacagccgca atatatccat tcactttaaa cgttttggca gcagaaaaag
    26161 caagaaagat tggcagaaaa taaaagacgg cattcgacgc agcagacaaa atatgataag
    26221 ttccgcttgt ttcactaagc cagccaatcg tagtcgctaa aacaaccaga ccttttaata
    26281 taccagaacc ggcaaacagc ggaatgatcg gcgtaaagat ttccgatatc aaaccaaata
    26341 gtttttcgat cggatttagc ttttctttcg gagctgaatg atcgatttga cgcgtcaatt
    26401 ccttgtaagc aggagccaat ccctgatcca tgattatttc tgcatatcta tcgagtaaaa
    26461 tgaaatactt aatggaaggg atttgctgtt ttaatttttc tgcattggct actggctgtt
    26521 ttttcaattt gatacgaagc cgagtcgcac atggaaggac agaatcaata ttgtcttttc
    26581 ctcccaactg ttcaatcagc atatgaatct gctcggacag taccatctgt tcaggattca
    26641 ttgtcgtttc cattagaaga ccactccact cactaatata atattggcgt aaggtgtcat
    26701 ttcgcctgta cgaataaatg catgacagtt attcaactct tttttcattt cttcatgtgg
    26761 gataaagcta atcggtgtat ctggtaacaa taatttgatt ttttccaata tttccgggtt
    26821 cattgtcttt atttcttccg ccaattcaat cgattgtacc tcaagttctt ctaaaacgtt
    26881 ttctaaaaca gataaaaaac ttggaagacc gtttgagaca gccaaatcta ttttttcagt
    26941 accaaagggg acaggcatgc ctgcatcccc gatacttaat ttatcaaagt gccccatttg
    27001 tgcgattact cgtgaaatat ctgaattgat tacttttcct tttttcatgt ttgtttcttc
    27061 ctctcattgt taattttaga ctgctgattg ttctaaagct tcgcggtaag ggatagaagg
    27121 ttgcgcacca taagactgca cagcaacaga agaggctaga tttccataaa ggatcgcttc
    27181 tttcaagtta ctaaggtctg gctgaagtgt gctgcttaat gcgccaataa atgtatcacc
    27241 tgcggctgtt gtgtcaacgg catccacttt aaaagcaggg acgataccgt gttctttttc
    27301 tgtatgatag aaagcgccgg cactgcctag tgtaatgatt actgttccaa tacctaattc
    27361 atggagtttt tcggctgctg cgaccaaact gttatgatct gtcactctga ttcctgtaat
    27421 gatttctgtt tctgtttcat ttggtataat gatatctgtc ttttcaagta gttcagtagg
    27481 aatcgtttca cgagctggtg caggattcag gatcgttgtt tttcctgcgt cttttgcaat
    27541 agaaaaagct aggatcgtcg catctaagct actttcaaac tgagcaataa taaagtcact
    27601 gtttgtaatc agttgcttgt tttttaggac ttcttgttca tggaaagcat tatttgcccc
    27661 tgcatggatc aagatactat tttctcctgc tgcgtctacc ataatcattg cttgtccggt
    27721 tgtggcgcct tggatttcag ctatcccaga tgtatcgatg ttttcttttg tcagtagatc
    27781 taataactgt tgtccttcgc tgtcagcccc aacgcctcca ataaaagatg tccgtgcgcc
    27841 tgaacgtttg gctgccactg cttggttggc acctttacct ccgccagcgt gaaaaatctc
    27901 atgcgcatgc atcgtttcgc ctggcttggg catgttggtt aaacgaaggg tagtgtccat
    27961 attaatactt ccaattactg taaccgtgtt cattttacaa acctccaact atctcattta
    28021 ttttgatggg aaaattattt tttaaaacgt tttagtaaaa cgttttaata gttcgataaa
    28081 aatatagcac accttgaaag ctatttcaag ggtgcagttg aaaatctttt ttctaatcgt
    28141 acaggtaatc ttttttcttc ccattctttt tctgggaatt ggatccgatc taacaataac
    28201 ttggcagatg tttgtcccaa ttcgaagatt ggttgtgcga tcgttgtcag tttcggcttg
    28261 atatactcgc acatatctat attatcatag ccaataatgc tgtagtcttc agggatgctt
    28321 tttccagctt cctctaatcc gcgatataat ccaaaagcta attcatcatt taaagcaaac
    28381 acaccagttg cagcagaatc aagaagttct gctgtgatct ggtagccacc ttgttttgag
    28441 aactgtgtag gtaagaggat cagttggtcg tgagggattt ggtaaacatc aagagcagat
    28501 ttaaacccct caatccgagc gtggacattt tccggtggat tttcaggata gacaagggcg
    28561 atcgtttgat gtcctagact aagcaagtgc atgcccgcta ggtaaccacc gcgaaaatcg
    28621 tctgttcgta cggcatcact aaatccttca gattttttct gatccaaaac aatgaagggc
    28681 cggccttgtt ttttcaaatt ttcgttgatt gcatctgtag agacagcaga agtcgcgata
    28741 atgaatccat ccacacctcg acgtgtgagc tcggctagat attcgatttc tttttgatga
    28801 tcagaatcag cattacataa tatcgtgacg aaattctgct tatacaagat atcctcaatt
    28861 cctcgcatca gtgtactgaa gaatggattc gtgatatcag gaacgagtac accaattgtt
    28921 ttcgtttcct tggtaatcat ttgtctagca aaatagtcag gctgatagcc taattcttct
    28981 ttggcagcta aaactttctg aacagttttc ggactgaatt tctccgtatt tccatttaat
    29041 atcaaggaga cagttgtgat tgaaacgccg gaaagtttag cgacttcttt gattgtgatc
    29101 ttttttttca ccatgttcat actcctatct aaatcctgtg gttattttcc catgaaatca
    29161 aaaagaagta aatgaaaatc acgtgtgcca gtacttattt gctttgttgg atagcttcga
    29221 ttatttgttt cgttgagcgt actcgtgcag ttttcggaaa tatctttttt atgaacaatt
    29281 gatgggattc tttgtcacga tcactgcaag catcttcagc aagcacgata tggtacccgt
    29341 gttgaaaggc atctaatgca gtagcatata caccgtttgt tgtcgctaca ccgcttaaaa
    29401 tgatagtttc gattccacgc cggcgaagtt gaagatcaag agaagtacca aaaaaagcac
    29461 ttggattgta ttttgtgata gtcaacatat tatctgtatc tttcaaagaa tccttcaaaa
    29521 gtaaatcagt gaattctgga ggtacagaag cagtcattcc acccatatca gtttgttgac
    29581 tcaaataagg gaaagtggag atgtctacgt tcactaaaac tttcaaggca gcggtacgtt
    29641 tcaatgttct tactaacaaa tcattgtttg tcagaataga tgctgcagtg tgtggagaga
    29701 gtgtaccgtt atttacgatc tctttttgca tgtcgatcgc gacaaaagca gtttttgata
    29761 aatcaaaaat catattttcc tttaaatcat tcatgatgtt ccttctttca aataacaatg
    29821 ttttttatgt aagtaaatca taaatcgttt atttgtcaac taaattaaag gattcctttc
    29881 tttagtctag agaaattcag tggtaaaata aataagtgtg agaaaacgca ttcgatgcat
    29941 agatatagcg agaaatatcg tgaaaatgga ggaatcagag tgaagtatgt cgaagtaaaa
    30001 aatgaataca aacgatacaa aatgggagaa acgaccatta cagcaaatga cgatatttct
    30061 ttttcaattg aaaaaggcga attagtgatt atacttggtc caagtggagc aggaaagtca
    30121 acgattctta atattttagg tgggatggat acacctgatg aaggtcagat cattattgat
    30181 gacacagata ttgcgcaatt ttcagataaa cagcttactg cttaccgacg aacagatgta
    30241 gggttcgttt tccaattcta caatctcgtt cctaatctaa cagcaaaaga aaatgtggaa
    30301 ttggcaacgg aagtttctcc tgatgcgctt gatcctgtag aggtattgag gcaagtgggc
    30361 ctagctcatc gattgaataa ctttccgtcc caattatcag gaggcgaaca gcagagggtt
    30421 tcaattgctc gtgcactagc taaaaatccc aaacttcttt tatgtgatga accgacaggc
    30481 gcgctggatt ttgaaacggg caagcaagta ttgaaattat tgcaaaacgc tagcagacaa
    30541 cacggcaata ccgttttgat cattacacat aattctgctt tagcgcccat cgctgataga
    30601 gtcattcaca ttaatgatgc taaagtaagg tctgttgaat taaatgatca tccttcatcc
    30661 attgatgaga ttgtatggta gggggatttt atgaaaacaa gaacatatct taaagcaggt
    30721 tttcgcgaaa ttcggcaatc taaaggacga ttcattgcaa tcatccttat tgtcatgcta
    30781 ggaacacttt tatttgtagg tgtcaaaact gctggacctg tcatgcaaaa aacgatggat
    30841 cactatgttg gtacagcagg actttctgat ttgcaaatcg tttctactgg tggcttgaca
    30901 caaaaagata ttgctcaagc agaaaagatc ccagatgcaa aagtagaaac aggaaaacag
    30961 atctattatt ccaatactgg caaaaacgaa gtgattcaaa tattttctta taacaaaaat
    31021 aacaagcaga acaagctaca attaactgat ggaaaactcc cggaaaaacc aaaccagctt
    31081 gtattggatg aaaaagcgga agatgaaggg tataaaatcg gtgatattta tcagattgat
    31141 tcagatgaat tgaaagaaaa agagtatacc atcacgggct ttgtccgttc tccattgttc
    31201 atcaacaatt tggagagagg atacgcgaac gtcggaaatg gtagcgtcga ttattttgtc
    31261 tatttacctg aatccgtttt taaaacagat atttattctg tcttatatct tgattttaca
    31321 aacgtaaaga atttgaatac gtacagcaaa gcttacaaag ataaaatgga gcaaaatcaa
    31381 gaaaaggcag aaaagtattt acaagatcga cccgaagaac gcttagaaga gctgaaaaaa
    31441 tcggccaacg aagaattaga accggcacag caaaaaatag cggatggcaa agcacaaaca
    31501 acgcaagcaa gaacacggtt agaagatgct aaaaaacagt tagcgcaaca gtcagcaact
    31561 atccagcagc ttcctgaagc gcaacgaaca atcgctgttc aaacattatc tcaacaagaa
    31621 gctcaacttg ctgaacaaga aaggcaatta gttgagaaag aacgtgaact ggcctctgca
    31681 gaggaagaat tgaatcgaaa tgcagaaaaa attgaaaatt taactaaacc atcataccta
    31741 tacaatgaac gttcagaaaa tgtcggtttt caagaatttg gtgatctgtc tgatcgtatc
    31801 gctgcgattg ccaatgtttt tcctgttttc tttttcttta ttgccgcatt gatcaccttt
    31861 acgacaatga cacgtatggt agaagaaaac cgcagggaaa tcgggacatt aaaggcgtta
    31921 ggttatacga aagttgaaat cgcaaaaaaa tatgcaatct atgcaagtct agcctcaggg
    31981 ataggtattg ttttaggaac gatattagga acgaatcttt tgccaaggat catttttgag
    32041 ctgtctaacg agcggtatga tattgggagt gcgcttattt tttatgactg gccgccgatt
    32101 ttacaagcag ctgccgcatt cttcattgcc gcatttggcg ctgcaatgat cgttttattc
    32161 aaagatttaa gagaacggcc tgctgcattg cttcaaccga aagcaccgaa gccagggaaa
    32221 cgcatttttc ttgaatacat cactccgctg tggtcacgcc ttagctttaa tcaaaaaatc
    32281 agttaccgaa atctcttccg atataagtca agaatgctta tggcgattat cggaattgct
    32341 ggatgtgccg ggctgatggt tgcaggcgtg ggattgaaag attctctaag ttctgtttca
    32401 gccaaacaat ttggaccgat cattgactat caagcaatcg ttacattgga ttcatccacg
    32461 gaagatagtc gtcaaaaagc agcggatatg ctgcagaagc aagaaaaagt aaatgagatc
    32521 ctagctattc atactcaaac cgtagaattg agaaaaaaag gacatgcttc gcaaagtctg
    32581 acagtgatcg taccaagtaa aacagctgat ttggatcgtt ttatccattt aactgatctt
    32641 gaagagaacc cacgctcctt gcctaaaaca ggaatcgcta ttacgcaaaa agtagcagaa
    32701 ctatttgact tatctacagg agatcatatt tcgctttatg atgaagatca aaaagaatgg
    32761 aaagtcgaag taaaagaaat cgtgaaaaac tatctaggta gctttattta tatgtcccct
    32821 gaatattatg cttcagttac tgatcaatcg atgatggata atgcattttt gctgcgtaca
    32881 gataagatga caacaaaaga agaagaaatg ctttccgaga aactgcttgc cacagacgct
    32941 gtgacaaata cgtctttcat gtccaaacaa atcgaaacgc aagaagaatc aatggcgaac
    33001 ttagactcgg ttgtcttaat ctttgtcgta ttatcaggac tgctggcttt tatcgtcttg
    33061 tataatctaa ctaatatcaa tatttccgag cgtgtacgcg aattatctac aataaaagtc
    33121 cttggatttt ttgataaaga agtcacgatg tacattgttc gagaaaatat catctttact
    33181 cttttaggaa tcatcggagg atttggtgta ggatatatat tgactgactt catcttgcaa
    33241 caagcgtcta tggagaatgt catctttcca ttagtgatca catggtgggc ttatgtctta
    33301 tcagcaggat taactatcgt atttacggtt attgtgatga ttgttaccca tttcaaatta
    33361 aagcatatcg atatgattga tgcgttgaaa tcgaatgaat aaaaacagag gttgtgaaat
    33421 cagcggtttg acctgagtat tagagaaaca aacggcaaaa tagtttttca tattttgccg
    33481 ttttttgagc taataccgaa ggacagctga ttgaacacca tgaatcagag gttgtaaaaa
    33541 agccgtcctg catcgagcaa aaagaatact caaataaaat tagctcctca tgttttacat
    33601 ttgagaagac tgattgccgt agataaaagc ttttgaacac catttataga agaaacaaga
    33661 atattttgct attttaaaca agaggataga caaatacatg tctgatctct tgttttttat
    33721 tgggcaacag acctcttaga atgtataaag ataaatttta caaacgcttt cggttcagtt
    33781 ataataataa atgataactt gtatatataa gttgtggtag gtaataaatc agttgaatgg
    33841 aggtaaatat ccatgacatt taaagacaaa gtcatttacc aaatctatcc caaatcttac
    33901 aaagacagta atggtgatgg aattggagat ttaaaaggaa tcaaagaaaa actcccgtat
    33961 ctgaatgatc taggcatcga catgatttgg ctaaacccta tttatccaag ccctcaaaaa
    34021 gacaacggtt atgatatctc tgattacaca gccatcgatc ctatctttgg tacgatggag
    34081 gaattcgaac agctaatagc cgaagcaaag aaataccgga tagaaatcat gctcgatatg
    34141 gtgctgaatc acgtttcgac agaacatgaa tggttcaaaa aagcactagc aggggaccag
    34201 cattatcagg acttcttcat tttaagagaa gagccaacgg attgggtatc aaaatttggt
    34261 ggaagtgctt ggtcgccatt tggagatacg gggaaatatt atttgcactt atatgatcgg
    34321 acacaagctg acttgaactg gcggaaccaa gcagtaagag aggaactatt caaagttgtt
    34381 cgtttttgga tggaaaaagg ggtaaaagga ttccgtttcg atgttatcaa tgttatcggt
    34441 aaagacgaac aattgaaaaa taataaagaa aatgatggca aacctgaata tacggacaaa
    34501 ccaatcaccc atacgtatct aaaagaattg aaccaagcaa cgtttgggac ggattccact
    34561 atcatcacag tcggtgaaat gagctctacg acgatcgaaa attgtatctt gtatacagaa
    34621 cctagtagag aagaattatc aatggtcttt aatttccatc atttgaaagt cgattatgaa
    34681 aatgggaata aatggtctac tcctccattt gattttgcag aattaaagcg actatttcat
    34741 acatggggag aaaagatgag tgagggtaac ggctggaatg ctctattttt taataatcat
    34801 gatcagccac gtgcgctcaa tcgatttgta gctatcgatc agtatcgaaa acaaggagca
    34861 gagatgctag caaccatgat ccatttgaac cgtgggacgc cctatattta tatgggagaa
    34921 gaaatcggca tgatcgaccc agactattca tcgatttccg actatattga cgtagaaagt
    34981 ttgaatgctt ataagttact ccttgaacaa ggattcacag aaaaagaagc gtttcgtcgg
    35041 atcaaagcaa aatctcgcga taactctcga acacccatgc aatggtcaga cacagaacaa
    35101 gcaggattta ctacagggaa accttggtta aaagttggag gcaagctaga agagattaat
    35161 gtagaaaaag aactatcttc tgaagattct attttgtcct attacaagaa attgattcgg
    35221 ctgagaaaaa catatccaat cgttgcacaa ggagattatc atgcttatga agcaaatcat
    35281 ccggaagttt atggctttct tcgccaattt gaaggacagc agctgcttgt attaacaaat
    35341 ttctatgata aagatacaag gatcgccatc ccagaaggat tcacagaagc caatattctt
    35401 atcgataatt attccgatac tgttcttcat caaagtctgg agctaaaacc ataccaggca
    35461 attgctttgc tgaaaaatta aaacaaaaac acaaaacgtc gttcctacga gctattctcg
    35521 taagatcgac gttttgtgtt ttatttaaaa taatcttctt cagaaaatga agagttttca
    35581 tactctcctt tatcgccata aaatttattg tagcgttgtt tgaatttacg gaaaataaaa
    35641 gtaacgagta atttgactaa cgtatagata ggaataccaa aaataacgcc cacaattccc
    35701 attagatcac ccatgacaag taaaacgatt aagatcgtaa tcggatggat ctgtaaacga
    35761 tcacccatta ctcgaggaat caccaagtca ccgtggagaa gttgtacggc aaaccagaca
    35821 atgacaaatt tgacagccat aaaagtagag tcttggaatg caatgatcaa acctggaaag
    35881 aaggcgataa acggcccaat atatggaatg atacataaca acccagcaga aatagctaaa
    35941 acactagcaa attctaatcc gatcagtaag aaacaaaccc agtagactgc tccaaggata
    36001 aatgaagcaa tgatttgccc ctttagaaat gaacccaatt gttgattagc aatctttgtc
    36061 aaatttttaa aatctgtacg aaatgctggt gggacaatcg ctaaaactga ctgataaaat
    36121 ttttgaggat ctctcaaaag gaaaaaagcg acaattggac cagtaaataa agtaataaaa
    36181 atagctgtaa cagttgaaaa aatgttgctg atccgttgtg cgccactttc ccaataattt
    36241 ccaataaatc cagctatatc agacgtcacg tcgtcaatag aagcgaaaaa ttgattaaat
    36301 gaatcggcaa aaggtgtttt ctccaaaaat tgtcggagac tctcttgaaa atcttgaaac
    36361 aaatctggca aactactgat caatgtcttt gcctgttctt caagaaaagg aataagccat
    36421 atgcttccaa gccccaataa aaataaaata atcacataaa cgataatgac tgacaagttc
    36481 ctcgaaaggt gcttgctcaa acgtttgatg actggttcca aaagataata caagatcagt
    36541 gcaaacaata atgggggcaa gatagtagcg ataatgattc cgacaggctt gaatataaac
    36601 gagatctgat ggaaaaaata aatgatcagc gcaagtaaga taactattcc taaaacatag
    36661 taagaggttt ttcctcctaa aaagcggatc aaacgattcg ttgtatctgt ttcttttttc
    36721 actctttttc ctcctttatc tataaattca ttatagacaa aagcgggtat aaaaggaaaa
    36781 tgatagaggt tgattgcaaa aatatcgtca atcattcata taaactttct catcaattaa
    36841 aataagaaaa cgcttgacag ttcttttaac catatgataa attaaatcct gttgctaaaa
    36901 cgtaactatt acggtttgcg aaaagcgaat cggaacattc aaatgaaaga agatgagaag
    36961 aggagtgtca taaatgaaac gattgatagg tatattggcc atgctggttt tagcaggtat
    37021 gttaactgct tgcggggcaa gtgggaaagc cgaggacagt aaagaaaaat tgagcgtgat
    37081 gacgaccttt tatcccatgt atgattttac aaaagcaatc gtcggggatg aaggagaagt
    37141 agagttattg attccagcag ggactgattc ccacgattat gaaccttctg ctaaagacat
    37201 ggcaaagatc caagatacag atatctttgt ttataatgat gaaaacatgg aaacatgggt
    37261 ccccgcaatc caaaaaacat tacaagaagg caatgtccat acgataaaag cgacagaagg
    37321 tatgctttta cttccgggaa gtgaagaagg acatgatcat gaccatgaac acggggaaga
    37381 aggccataca catgagctag acccacatgt atggctagct ccaagtttag caatcaagca
    37441 ggtagcaaac atacgtgatc agctgattga agcttaccca gaaaaacagg aagtatggac
    37501 aaaaaatgca gcagcctata ccgagaaact tcaagcactc catcagcttt atcaagaaac
    37561 ctttaagcaa gcaaaacaaa gatcttttgt cacgcaacat gctgcattca actatctagc
    37621 gttagaatat ggattgaatc aagtatcgat tgctggtctt tcttctagtg aagaaccgtc
    37681 tgcggcgaga attgctgaac tgaaacactt tgttaaagaa catggaatca actatattta
    37741 ttttgaagaa aacgccaaag atagtattgc cagaacgtta gcaaacgaag caggtgtatc
    37801 tttagaagta ttgaatcctt tggaaggatt gacgaatgaa caaatagaaa atggagaaaa
    37861 ctatctttct atcatggaag caaacctcga agcgttgaaa aaaacgacag agacagaaaa
    37921 cccgctagaa gatactttga cccccaaaaa agaaaagagc gtctacaacg gttattttga
    37981 agacgaggat gtacaagatc gctctctttc agattgggca ggaacttggc aaacagtaga
    38041 tacgtatgta gaagatggga cttttgatcc tgtttttgaa tataaagaaa aattgaatca
    38101 ggataagaca gcacaagaat ataaagaata ttatacgaag ggctatcaaa cagatattgc
    38161 ttcaatcaag atcagtgaga aagagatggc atttacgttt aagaatggaa caacgaaacg
    38221 ttcaaattat cgttatgtag ggaaagaaat cttgacctac gaggcaggaa accgtggcgt
    38281 aaggtatcta ttcgaagcag aagataagga aagtggcgct tttagatata ttcaattcag
    38341 tgatcacacg attgcaccgg ctgactccga acattttcat ttatatgcag gaaatgaaag
    38401 tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag atacaatgga
    38461 tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga accgaagggt
    38521 ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg aaatcaattt
    38581 ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga cttctctggt
    38641 ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat gacaacggat
    38701 aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta attgggcatg
    38761 agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat attggatgtc
    38821 tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat ctttttggat
    38881 ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat tttcttttaa
    38941 atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt ttaagatttt
    39001 catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat ctaattcacg
    39061 gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga tatctaaaaa
    39121 gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt ccggatcaga
    39181 ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt tgatcaccgt
    39241 tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa tcatatcatt
    39301 actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt caattgatgt
    39361 ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca agccaaggcc
    39421 ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt ttaacggtaa
    39481 tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct tgagtatggt
    39541 caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt ccaagataat
    39601 accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg gctcaggaaa
    39661 atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg acagtaaact
    39721 acggatctca ggaactttca tattatccaa catacttaga ttggccggaa aaaggttcat
    39781 catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt ctaagtcgcc
    39841 ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt tgaattctct
    39901 caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc tgacttgttg
    39961 ctctaataac tgatcagcta atttcttatt agagattttc caataataaa ccaagatgat
    40021 cagggcaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga catcaggtgt
    40081 ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata tcaatgtccc
    40141 gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg atttttttaa
    40201 acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat actgcaatga
    40261 atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc ttgttaagtg
    40321 atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt gttgacgcga
    40381 agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag cagtaaaaat
    40441 ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga ctcccgcaaa
    40501 cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt aaatcaaata
    40561 ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt taccaaatta
    40621 tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca gaactcatac
    40681 caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta atgattgttt
    40741 ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag caacgtagct
    40801 atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga gaaaaataac
    40861 gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg gggacgtttc
    40921 tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag taacaaaaag
    40981 cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag atgtttcatc
    41041 accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa ttcagagtcg
    41101 gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt gattcctgtt
    41161 tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt tccaagatta
    41221 ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc ttccgatttg
    41281 tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat ctcatacgta
    41341 cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc ataaaaagtg
    41401 gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca agaaccttac
    41461 caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg tgctttttcg
    41521 agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat tcttatggaa
    41581 aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt atttgaatca
    41641 ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg tgtcatgaaa
    41701 tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt tgtacgcaaa
    41761 tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga ggttgtgagt
    41821 ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc atgttttatg
    41881 aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa aaaagggctg
    41941 cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt ggctactttt
    42001 agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata aatgaagtag
    42061 taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc attgttgcag
    42121 gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat ttagaaacaa
    42181 aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat tctaatccag
    42241 aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg gcaatcaaag
    42301 atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat agtatgctgt
    42361 ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag tatgaaggtc
    42421 ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa ccagatctac
    42481 tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa agaggccggg
    42541 aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa ctcaatcgac
    42601 gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc gatggggaca
    42661 aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa atcaagatgc
    42721 gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact acaaataacc
    42781 cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat tgctcactcg
    42841 cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga gatcaaatag
    42901 tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg gccatgatca
    42961 aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga cagaaaacaa
    43021 ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa aatcgatcaa
    43081 aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc ccttttaaat
    43141 ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa gctacccact
    43201 ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca tggacgggtg
    43261 tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag cgccagaaat
    43321 gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc cctaagaaaa
    43381 agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca aatgcttgga
    43441 tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat tggatataag
    43501 tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta cgcccctcgt
    43561 gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt ccttatctta
    43621 gcataaacga ttgaaaaaaa ggaaaaattt tcagaaaact aaaatcatat cgcttcccat
    43681 tttcattttt agaaaggtct gttagtataa agaaaaaata gacaacgaaa ctttaaataa
    43741 ccaacttgaa ataaacaaat tcaaagaaga aagatgggaa ggaaatcaat cagttgaatg
    43801 aaaaagaaat tctccgatta caaaaagaat tgaaacgctg ggagaacaag tataaaaagc
    43861 ttcaacaagt ctttcggcta caagaagaaa tcattgctac ctatgaagcg gcttatggcg
    43921 aagcacccgg acttattgag gaagaagtac aagtaaaaga aagtgaagga aacagctctt
    43981 tctttaaaat gatggagaaa cgttcctata atcgcttcaa tcaagaacaa aaagcagcta
    44041 tcacatatga tatgaagaaa catcttcgaa tcatagcagg agctgggagc ggcaaaacgc
    44101 aaacaatctg tgcaaaagct gtttatctga tgacgcaaaa acaagtagac gaagaacgca
    44161 tactaatgat cacttttaca aggaacgctg caaatgaact aaaaaaacga gtagataatt
    44221 tcagccagag aaaaaccgct gtccatatcg gaacattcca tagtatcttt tttaggatat
    44281 acaatgaaat ttgtcgaaaa tttcctgaag tagcaatgca aggaatacaa ggagactttt
    44341 caaaggatac tgcacaaaaa gtgaatgctg ttttgcaaca gctgatacgt aaatataatc
    44401 tttatatatt tgatcaatat ggagaaaaaa cgattgcttc tcggttagac tattggcaga
    44461 atatgaacct ttcagtagaa gaaatggttc agttagttaa agaaaaatat gattccattg
    44521 ataagaatgc acgacagccg atatcagaac gactgtatgg attgctcacg gaactccaag
    44581 aacaaaaaag aagccagcaa ttgctagagt tcaatgatgt actccaaaat ctgaaaagcg
    44641 ctttggagaa tgaggagatc cagcattata tcggccaaaa atatgattat ctattcattg
    44701 atgaatttca agatactaat ccacttcaat gggaaatcgt gaaacggatg acaaaggaaa
    44761 acaggatcaa gttgattgtt gttggagatg atgatcagag tatctatgga ttcagaggat
    44821 cagagccagc atacatcaag aactttgaaa aagaatatcc taccaaaact cttttcttat
    44881 taactaatta tcgttctcgg gcagctattg tccaaggagc aaatagattg atcagctata
    44941 ataaaaatga tcggatacca aaggcgatga ttccagcaca aaaagaagca ggtgttatgg
    45001 aagcctattt gttttctgat actaaagcag aaagtcagtg gctaatcaaa caaattcaga
    45061 catttattca aaaaaatggg aaatataagg aatcaatcat attataccga tcagcttcac
    45121 aaacgcagca gcttgtccaa tctctgctga aaacgaatat tccttttgta ctggaagcag
    45181 atagtccata tgaaggtatc tttggtatca agtctttcca acatttctat caaaaaattg
    45241 ttcattggca aacagcactg aatctgcaaa agaaaaatca ggcctaccag caattgctcc
    45301 ggcagctgat ggcagactgc tacctgaaaa aaagtgaatg cgatcaatac ttttctccta
    45361 aatatcaaaa tatagccgtt gcagattata ttttgtcgat aagccccaat ttaaaatcga
    45421 aatctgcaga aatccgagag tttgaggaag cgttgcgtaa aacagaccag catcaagaaa
    45481 tctattcgct tgttcaaagc tatcttcatc tgccacgtat agctaaggaa atcgaccaga
    45541 gtgatcaaga atggatacga gaagaagtaa agcagcatgc tactttcaga agactccaag
    45601 ccttatcgca agaaacccaa gcgacagcta aagaattaaa aacccgcttg attgcttaca
    45661 gacaaggaaa acttgatgca ctatgtatcc agagcattca caaaagtaaa ggtcttagtt
    45721 accgaaatgt ctttttgatt ggttgtaacg aaggaagttt gccttataac ggagcgacag
    45781 aaaagaaagt aatcgacttt aatgaaataa aagcagaacc agtaacgacg atagaagaag
    45841 aacgaagact attttatgtt gcgatgacta gagcaagaaa tcgtctgtat ctatgtgtac
    45901 ctcaaatgaa aaattcaaga aaattgaaag tatcgagatt tatcaaagaa accgggagtc
    45961 gtgtgaaaaa aggaaagtga tagaagagag ggtgtgacag aagtggtcag tttcaagaaa
    46021 gaagaaggaa tgtacgaaaa ttgcttctca aatttttgtg aaatttcagc ttattttcga
    46081 agaagctatt tctggaacac agtttattcg gaaaagggag gtgtgacaag aattttgtca
    46141 cacctccctt attta
//
LOCUS       DAZKNV010000019        43107 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000019 DAZKNV010000000
VERSION     DAZKNV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.019"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            637..1602
                     /locus_tag="ACG8M1_001140"
     CDS             637..1602
                     /locus_tag="ACG8M1_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HFQ0421866.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            1624..1836
                     /locus_tag="ACG8M1_001141"
     CDS             1624..1836
                     /locus_tag="ACG8M1_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFQ0421867.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            1911..2387
                     /locus_tag="ACG8M1_001142"
     CDS             1911..2387
                     /locus_tag="ACG8M1_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HFQ0421868.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            2384..4192
                     /locus_tag="ACG8M1_001143"
     CDS             2384..4192
                     /locus_tag="ACG8M1_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFQ0421869.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            4269..4484
                     /locus_tag="ACG8M1_001144"
     CDS             4269..4484
                     /locus_tag="ACG8M1_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HFQ0421870.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            4576..5439
                     /locus_tag="ACG8M1_001145"
     CDS             4576..5439
                     /locus_tag="ACG8M1_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HFQ0421871.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            5476..6012
                     /locus_tag="ACG8M1_001146"
     CDS             5476..6012
                     /locus_tag="ACG8M1_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MT-A70 family methyltransferase"
                     /protein_id="HFQ0421872.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            6026..6448
                     /locus_tag="ACG8M1_001147"
     CDS             6026..6448
                     /locus_tag="ACG8M1_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HFQ0421873.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            6378..8777
                     /locus_tag="ACG8M1_001148"
     CDS             6378..8777
                     /locus_tag="ACG8M1_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HFQ0421874.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            8809..10800
                     /locus_tag="ACG8M1_001149"
     CDS             8809..10800
                     /locus_tag="ACG8M1_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFQ0421875.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            10823..11074
                     /locus_tag="ACG8M1_001150"
     CDS             10823..11074
                     /locus_tag="ACG8M1_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HFQ0421876.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            11064..12293
                     /locus_tag="ACG8M1_001151"
     CDS             11064..12293
                     /locus_tag="ACG8M1_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HFQ0421877.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            12290..14371
                     /locus_tag="ACG8M1_001152"
     CDS             12290..14371
                     /locus_tag="ACG8M1_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFQ0421878.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            14520..18440
                     /locus_tag="ACG8M1_001153"
     CDS             14520..18440
                     /locus_tag="ACG8M1_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodL domain-containing protein"
                     /protein_id="HFQ0421879.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLPNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            18441..19385
                     /locus_tag="ACG8M1_001154"
     CDS             18441..19385
                     /locus_tag="ACG8M1_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421880.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            19389..19592
                     /locus_tag="ACG8M1_001155"
     CDS             19389..19592
                     /locus_tag="ACG8M1_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HFQ0421881.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(19892..20128)
                     /locus_tag="ACG8M1_001156"
     CDS             complement(19892..20128)
                     /locus_tag="ACG8M1_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421882.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(20311..20682)
                     /locus_tag="ACG8M1_001157"
     CDS             complement(20311..20682)
                     /locus_tag="ACG8M1_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HFQ0421883.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(20679..22007)
                     /locus_tag="ACG8M1_001158"
     CDS             complement(20679..22007)
                     /locus_tag="ACG8M1_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFQ0421884.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(21968..22297)
                     /gene="mobC"
                     /locus_tag="ACG8M1_001159"
     CDS             complement(21968..22297)
                     /gene="mobC"
                     /locus_tag="ACG8M1_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFQ0421885.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(22555..22926)
                     /locus_tag="ACG8M1_001160"
     CDS             complement(22555..22926)
                     /locus_tag="ACG8M1_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0421886.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            23071..23256
                     /locus_tag="ACG8M1_001161"
     CDS             23071..23256
                     /locus_tag="ACG8M1_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFQ0421887.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            23414..23581
                     /locus_tag="ACG8M1_001162"
     CDS             23414..23581
                     /locus_tag="ACG8M1_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421888.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            24199..24866
                     /gene="vanR-B"
                     /locus_tag="ACG8M1_001163"
                     /pseudo
     CDS             24199..24866
                     /gene="vanR-B"
                     /locus_tag="ACG8M1_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
     gene            24869..26212
                     /gene="vanS-B"
                     /locus_tag="ACG8M1_001164"
     CDS             24869..26212
                     /gene="vanS-B"
                     /locus_tag="ACG8M1_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFQ0421889.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            26383..27189
                     /locus_tag="ACG8M1_001165"
     CDS             26383..27189
                     /locus_tag="ACG8M1_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HFQ0421890.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            27207..28034
                     /gene="vanW-B"
                     /locus_tag="ACG8M1_001166"
     CDS             27207..28034
                     /gene="vanW-B"
                     /locus_tag="ACG8M1_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HFQ0421891.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            28031..29002
                     /locus_tag="ACG8M1_001167"
     CDS             28031..29002
                     /locus_tag="ACG8M1_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFQ0421892.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            28995..30023
                     /gene="vanB"
                     /locus_tag="ACG8M1_001168"
     CDS             28995..30023
                     /gene="vanB"
                     /locus_tag="ACG8M1_001168"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFQ0421893.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            30029..30637
                     /locus_tag="ACG8M1_001169"
     CDS             30029..30637
                     /locus_tag="ACG8M1_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFQ0421894.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(30889..31893)
                     /locus_tag="ACG8M1_001170"
     CDS             complement(30889..31893)
                     /locus_tag="ACG8M1_001170"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0421895.1"
                     /translation="MQRGGKSRGKAAAAGSGKQKASNGERFLKKIERTGGEAVNRLTR
                     RRKVYEAIHTLRQEKGYEIASLCALSGIPRCSYYKWLHREESASEKENTLLLEEIIRL
                     YSEVKGIYGYRRMTLNVNSRLKRNYNHKRIYRLMKSVHMQAVIRRKKKHYVILEPRVT
                     AENVLNREFTANGPNEKWLTDVTEFKLINGKKAYLSAILDLHDKSIVAYALGQSNNNQ
                     LVFDTFDRAVRANPGAHPLFHSDRGYQYTNRQFKAKLDGIHATQSMSRPGRCIDNGPM
                     EGFWGILKSEMYYLRQFHTFEELKKAIDEYIDFYNTRRLQAKLKGLAPLAYRNQTLVA
                     "
     gene            complement(31776..32459)
                     /locus_tag="ACG8M1_001171"
     CDS             complement(31776..32459)
                     /locus_tag="ACG8M1_001171"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0421896.1"
                     /translation="MSLKGKIPPEVKIQAVEDYLAIRKGSTQIREELGIRLSTFQAWL
                     RKYQTEGPAGLHPKKHVTSYPSSLKLAAVEDYMGGGGSLDAMCRKYGISSHAVLQQWI
                     TLYNQGHREFKTRRAREETDMAEKEKLSQEQKLQAVLYCLEHQLDYRRTSEQYKITYQ
                     QIYSWVKKYQEQGEAGLLDRRGRRRPPSEYSEEEKAAAKLRQLEAENRRLQMENDFLK
                     KLNELEGRR"
     gene            32905..33336
                     /locus_tag="ACG8M1_001172"
     CDS             32905..33336
                     /locus_tag="ACG8M1_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0421897.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
     gene            33343..33576
                     /locus_tag="ACG8M1_001173"
     CDS             33343..33576
                     /locus_tag="ACG8M1_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0421898.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            34000..34200
                     /locus_tag="ACG8M1_001174"
     CDS             34000..34200
                     /locus_tag="ACG8M1_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFQ0421899.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            34284..35477
                     /locus_tag="ACG8M1_001175"
     CDS             34284..35477
                     /locus_tag="ACG8M1_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0421900.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(35656..35934)
                     /locus_tag="ACG8M1_001176"
     CDS             complement(35656..35934)
                     /locus_tag="ACG8M1_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421901.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFF"
     gene            complement(36052..36312)
                     /locus_tag="ACG8M1_001177"
     CDS             complement(36052..36312)
                     /locus_tag="ACG8M1_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421902.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(36449..36862)
                     /locus_tag="ACG8M1_001178"
     CDS             complement(36449..36862)
                     /locus_tag="ACG8M1_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFQ0421903.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(37318..37803)
                     /locus_tag="ACG8M1_001179"
     CDS             complement(37318..37803)
                     /locus_tag="ACG8M1_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421904.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(37942..38157)
                     /locus_tag="ACG8M1_001180"
     CDS             complement(37942..38157)
                     /locus_tag="ACG8M1_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFQ0421905.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            38381..39181
                     /locus_tag="ACG8M1_001181"
     CDS             38381..39181
                     /locus_tag="ACG8M1_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0421906.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNVSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            39200..41068
                     /locus_tag="ACG8M1_001182"
     CDS             39200..41068
                     /locus_tag="ACG8M1_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFQ0421907.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            41061..41552
                     /locus_tag="ACG8M1_001183"
     CDS             41061..41552
                     /locus_tag="ACG8M1_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFQ0421908.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            41540..42094
                     /locus_tag="ACG8M1_001184"
     CDS             41540..42094
                     /locus_tag="ACG8M1_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFQ0421909.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            42112..43107
                     /locus_tag="ACG8M1_001185"
     CDS             42112..43107
                     /locus_tag="ACG8M1_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFQ0421910.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT        11649 a        10313 c        11040 g        10105 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaatttta ggttatcgct gaaaaccccg
      181 gaaatacggg catttcgcag gatatgagaa ctcaatttac taccaattta ctactttcgg
      241 attgagccgc atatatgctg aaccatactg ctaatacccg ccaccccaaa tacggcacat
      301 cataaattga atacgacacc gtaaacgcgg cgttcctctt tcccgtcatg ggagaacagg
      361 acgccgcttt tttatgccca aatagagaaa ggaggcgacg ccatgctatt tacttccggc
      421 cctgaccggg cgtttgaacg gctgatgcag gaaaagcccg gtttcgatca ctacgacggc
      481 ggcggggcgg acgcgccgga ggattgcggc acctgccgat tttaccgccc ggattggaaa
      541 tatcaattct gccagtttgc agagtgtccc tatcagccgg gcaagctgac cgactatgca
      601 gcggtcaaat tcacagtgaa aggagcgaac aacgctatgg cagttttccg tgtggaaaag
      661 aacaaaggct atacggtgat gtcaaatcac cacctgcgga ataagaacct gaccttaaag
      721 gccaagggcc tgctgtcgca gatgttgtcc ttgccggagg attgggacta taccctaaaa
      781 ggactgtcct atatcaaccg ggaaagcatc gacgcgatca ggacagcggt atgggagctt
      841 gaaaaagctg gatatatccg gcgtgagcag ggccgtgacg caaaaggcaa aatggccgat
      901 atggtctata ccatctacga acagccggta ttggaaaacc cggtattgga aaatccaaca
      961 tcggataacc cggtgttgga aaatccgaca tcggataatc cggcgtcgga aaatccaacg
     1021 caattaaata aagaagtaca aagaactgac ttatcaaaaa aagaaaaaat aattacagat
     1081 ggacaaagta cccattccat tcctatccca tccccgaccc ctgcccctat ggagggcgag
     1141 gcagcggcta cgccgccgga acggaaaagg acaggaaagg atgaggctgt acggatttat
     1201 cgggaaatca ttttggagaa catcgagtat gcctatctca ttcaggacag gagcattgac
     1261 cgtgaacagc ttgacgaaat cgtagacctg atgctggaaa ccgtctgcac cgcccgaaag
     1321 acaatccgtg tcgccgggga cgactaccct gccgagctgg tgaaatccaa gtacatgaag
     1381 ctgaccggcg aacatatccg ctttgtcctt gactgtctgc gggagaacac aacgaaagtc
     1441 cgcaatatca aacaatacct gcgggctatg ctgttcaacg cccccagcac catttccaac
     1501 tactacacgg cccttgtcgc gcacgacatg gcacagcccg attggggaaa gcctaaatcc
     1561 ggcctgccgg actattcctg cggcgagggc gaaagcctgt aacgagaaaa ggaggacgac
     1621 cctatgaagc agggcgcatt gatttttgac gagcgaacag accgttacga catccgcttt
     1681 gatctggccg actattacgg cggcctgcat tgcggggagt gtttcgacgt gatgatcggc
     1741 ggcaaatgga ggcccacccg cattgaaatg gccgaaaact ggtatcttgt cggcatccgg
     1801 gccgacgacc tttccggcct gcgggtgcgg atttgaccta tatctacctg cggcgtctgg
     1861 tggttccgcc ttagacgccg cttttgactt tctgacaagg agggatgcga ttgcaggaag
     1921 aagttactca aaagaccatt gccctgtcca tgaaaacggg caagctcacg gctcaagtgc
     1981 tgcaagcggc gctgaaaaag tacctgcaac accgggccaa gggcaaaaac acgctgcacc
     2041 acggccagca gagcctaaag cagcttaaaa agcatggggc tgatctctcc aacattgaga
     2101 tcaccgaggc caacattgga gcgttcaagc catgcgccaa gaaatacggc gtggatttta
     2161 ccttacgaaa agataagacc acccagccgc cccactacgt tgtgattttc aaggccaagg
     2221 atgcagataa ccttgatctg gcgtttcggg agtttaccgc caagacgctt tccaaggagc
     2281 agcggccctc tatccgcaag gttttgtccg ctgtgaagca aaaggcggcg gcccagacca
     2341 agcagcgggc caaggagaaa atcaaggaaa gggggctgga actgtgaagc ctgacgtaaa
     2401 gaaattgctg atcctgaacc tcccgtatct gatttttgtg tacctgtttg cgaaatgcgg
     2461 ggaggcgtac cggctggccg ctggtgctga cctgtcgggg aagctcctgc attttgcgga
     2521 tggttttgcg gcggcttttg ccaacccgct gccaagcctg cacctgtttg acctgtgtat
     2581 cggtatcgcc ggtgccgtga tcgtgcggct ggtggtgtac tgcaagagca agaacgtgaa
     2641 gaaataccgc aaaggcatgg agtatggcag cgcccgctgg gggacggcca aagacatagc
     2701 gccttacatc gaccccaagt ttgaaaataa tatcctgctc acccaaacgg aacggcttac
     2761 catgaccggc aggcccaaag accccaagac agcgcggaat aaaaacgtgc tggtgatcgg
     2821 tggcagcggt tcagggaaaa cgagattttt cgtgaaaccc aacctgatgc aatgctttcc
     2881 gaccacggac tatccgactt cgtttgtggt gacagatccg aaaggcactt tggttctgga
     2941 aaccggcagg atgttccagc aggcgggcta ccgcattaaa atcctgaata ccattaactt
     3001 ttccaagtcc atgaagtaca acccctttgt ctacatccat tcggaaaagg acgtgctaaa
     3061 gctggtaaat accctgattt ccaacaccaa gggcgagggg gaaaagtcag cggaggattt
     3121 ttgggtgaag tcggaacggt tgttttattc ggccctgatc ggctatatct ggtacgaggc
     3181 cccagcggag gaaatgaact tctcaacgct gctggaaatg ataaacgcca gtgaagcccg
     3241 cgaggacgac ccggagtttc aaagccccgt cgatctcatg tttgagcgtt tggagcagaa
     3301 agaccccgac cattttgcgg tgcgccagta caagaaattc ctgctgtccg caggcaagac
     3361 ccgttcttcc atcctgattt catgcggtgc cagacttgcg ccctttgaca tccgggaggt
     3421 acgcgagctg atggaggacg acgaaatgga gctggacacc atcggggacg aaaagacggt
     3481 gctgtatctc attatgagcg atacggacac gacctttaat ttcattctgg ctatgctcca
     3541 aagccagcta atcaacctgc tttgtgaccg ggctgatgat gtgtacggcg ggcggctgcc
     3601 tgtccatgta cgcctgattt tggatgaatt tgccaacatt ggccaaatac ccaatttcga
     3661 taaactcatt gccaccattc gaagccgtga aatatcggcc tctattattt tgcagagcca
     3721 gtcgcagcta aaagcgattt acaaggacgc cgccgagatc atttcggata actgcgatag
     3781 tgtgcttttc cttagtgggc gcggcaaaaa tgccaaggag atttccgatg cgctggggaa
     3841 agaaacgatt gacagtttca acaccagcga gaaccgggga agccaaacgt cccacggatt
     3901 gaactatcaa aaattaggaa aggagttgat gtcccaagac gaaattgccg tgatggacgg
     3961 cggcaagtgt atcttgcagc tacggggtgt gcgcccgttt ttatcggaga aattcgatat
     4021 taccaagcat ccccggtaca aataccttgc cgacgccgac aagaagaata cctttgacgt
     4081 ggacagattt ttgactatca cgcgccggaa acggcagcaa gtggtaacgc aggatgaagt
     4141 attcgacctg tatgaaatcg acctgtcgga cgaggacgcc gccgctgaat aaacagcggc
     4201 ttttttcatt ccaacaacaa aatcaaaaaa tcattatgag ccggaaaccg gcagaaagag
     4261 gtaaatttat ggcatttttt aattccgcag ttactacttt gcagactatc gtgatcggac
     4321 tgggcggcgc tctgtgcgta tggggcggca tcaatctgtt ggagggatac gggcaggaca
     4381 atccgggggc aaaatcgcag ggtgtcaagc agcttgtcgc tggcggcggc gtggccctga
     4441 tcggtgtcac tctggttccc ctgctgtccg ggctgctggg ctgatcctgg cctttgtccc
     4501 tgtccaaacc cttaactaat cgcctccgcg tcctcccggc cagaccggga gggcgcggga
     4561 aaggaggtgc tacccgtgat tagtgaaatc attgaagaat ggataaaagg catcctcatg
     4621 gacggtatca cgggcaacct gtccgggctg ttcgatacgg taaatgccaa agtcggagaa
     4681 atcgccgccg acgtgggacg aaccccgcag gcatggaaca gcggtatttt caatatgctg
     4741 cacagcctgt cggaaaccgt gatcgtcccc atagccgggg ccatactcgc ccttgtcatg
     4801 tgctatgagc ttatccagat gataacggaa aagaacaata tgcacgactt tgacagctcc
     4861 atgttcttcc gctggatatt caaatccgcg tttgcaatcc tgatcgtaac gaacacatgg
     4921 aacatcgtca tgggcgtatt cgacgccacc caaagcgtcg tcaatcaaag cgccggtgtg
     4981 attatcgggc agacatccat tgattttaac accctgatac cagaccttga aagccaattg
     5041 gaggctatga gcgtgggcgc tcttttgggg ctgtggttcc aaacccttgt tgtgggcctc
     5101 accatgaata tcctttccat ctgcattttc cttgtgacct atggccgcat ggtggaaatc
     5161 tatgttgtca cgtcgctggg gcctatcccc cttgccacaa tgggcaacgc ggaatggcgc
     5221 ggcatgggcc aagggtatct gaaatccctg ctggcgctgg gcttccaagc ctttttaatc
     5281 atggttgtgg tgggtatcta cgcggtgctg atacagaata tcggttccgc ttccgacata
     5341 tccggcgcaa tctggggctg tatgggctat acggtgctgc tgtgcttctg cctgttcaag
     5401 accggcagta tatcaaaggc cgtattcggg gcgcattgat cccaaaatcc aagcatacac
     5461 aggaggaact tgtttatttc aacgtacaac atcatttacg ctgacccgcc gtggcggtat
     5521 gactgcaaaa acgtacaggg cgcagcggaa aatcactatt ccaccatgag cattgacgag
     5581 ctgtgcgccc tgccggtgga acggctggcg tccaaagact gcctgctgtt tttgtgggcc
     5641 acattcccca tgctgccgga agctctgcgg ttaatcaaag cgtggggctt ttcattcaag
     5701 accgtggctt ttgtatggct gaaacagaac cgtaaaagcc ttacatggtt ttacgggctg
     5761 ggccgctgga caaggggaaa cgcggaaatc tgcctgctgg caacacacgg caagccgaag
     5821 cgtcgttctg cctctgtcca tcagtttatt atcagcccga ttgaacaaca cagcaaaaag
     5881 ccggatgtga cccgtgaaaa aatcgtagag ctggcgggcg atttgccccg cgtggagctg
     5941 tttgccagac agaaaacccc cggctgggac gtgtggggga acgaggtgga atgtgacctt
     6001 atcctgacgt gaaaggaggt gccaaatggc ttatgtaacc gtccccaagg acttaaccca
     6061 tgtgaaaagc aaggttgtgt ttgggcttac caaacggcaa ctgatctgtt tttccggggc
     6121 gctggtgatc ggcgtcccct tatattttct cacccgtgac tatcttacca acagcgcggc
     6181 ggccctgctc atggtatttg ccatgctgcc gggctttttg cttgccatgt acgagcgtca
     6241 cggccagccc cttgaagtgg tgattatgca gatcatccag tgctgcttca tccagccaaa
     6301 ggagcgtccc tatcagaccg acaacaccta caccgccctt gtgcggcaat accagatgga
     6361 acaggaggta aaggccattg tccaaaaagg aaatcccaag agaaaccgaa aaaacaaagc
     6421 tgacccgcgc ccagcgaaaa gaaattgacg cggtaatccg taaatataag ggcgacggca
     6481 ggccccacac ggcgcagcag agcatcccct acgaggtcat gtacccggac ggcgtgtgcc
     6541 gggtatcgcc cggcgtcttt tccaagtgca ttgagtttgc ggacatcagc tatcagcttg
     6601 cccagccgga cacgcagacg gctatctttg aaaaactgtg cgacctgtat aactatgtgg
     6661 acgcctccat tcatatccag ttttctttcc tcaatcggaa agttgacccg gtgcagtacg
     6721 ccaagagctt tgagatcgcg ccgcaggggg acgacttcga cgacatccgg gccgagtaca
     6781 ccggcattct gcaaaagcag cttgcaaacg gcaacaacgg catggtaaag accaaatacc
     6841 tgacattcac catcgaggcc gaaagcgtga aagcggcgcg agccagattg aagcgcatcg
     6901 gctttgacct gttaggctat ttcaagagca tgggggccgt agcccatgtg atggacggct
     6961 gggaacggct gaacctgctg catggcgtgt accacccgga cggcgagata ttcaattttg
     7021 actggaagtg gctggccccg tccggcctct ccaccaagga ttttattgcc ccgtcctccc
     7081 tgtgcttcgg caatgcaaag acattcggca tgggcggcaa atacggcgcg gtaagtttcc
     7141 tgcaaatcct gtccccggag ctgtcggacg atatgctggc cgacttcctc aatacggaaa
     7201 gcggtgtttt agtcaatctc catgtgcagg ccattgaaca gaccaaggcg atcaagacca
     7261 tcaagcgcaa aattaccgac cttgacgcta tgaagattgc ggagcagaaa aaggccgtcc
     7321 gcagcggtta cgatatggac attcttccca gcgaccttgc cacctacggc gaggacgcca
     7381 agaagctgct gacaaagttg cagacccgca atgaacggct gttccagttg acgttccttg
     7441 tcctcaacgt ggccgacacc aagcaaaagc tgaataacga cgtgttccaa gccgcaggcg
     7501 tggcccaaaa gcataactgt ccccttgtcc ggctggacta ccagcaggaa cagggccttg
     7561 caagcagcct gccgctgggc gtcaatcaga tcaagataca gcgcagcctt acgacttcca
     7621 gcgtggccgt gttcgtcccc tttgtgacgc aggagctttt tcagggcggc gcggccatgt
     7681 attacggcat caacgccaag tcccgcaaca tgattatgct ggacaggaag caggcccgtt
     7741 gccccaatgc cttgaagctc ggcacccccg gcagcggcaa atccatgagc tgtaaatccg
     7801 agatcgtcag tgtgttctta acgacgcctg acgatatttt tatttcagac ccggaggccg
     7861 aatattaccc ccttgtcaaa cggctccacg gacaggtaat ccggctgtcg cctaccagca
     7921 aggactttgt gaacccgctg gacatcaacc tgaattattc ggaggacgat aacccgctgg
     7981 ccctgaaatc cgactttgtg ctgtcgttct gtgagcttgt catgggcggc aagaacgggc
     8041 tggaagccat tgaaaagacc gtgatagacc gggctgtgcg cgtgatctac cggccctatc
     8101 tggcagaccc ccgcccggag aatatgccga tcctgtccga cctccacaaa gcgttgttag
     8161 atcagcatgt cccggaggct gaccgggtgg cgcaggccct tgacctgtat gtgtccggct
     8221 ccctgaacgt atttaaccac cgtaccaacg tggacatcgg caaccggctt gtgtcctttg
     8281 acattaagga gctgggcaag cagctcaaaa agctggggat gctcattgtc caagaccaga
     8341 tatgggggcg cgtcacggcc aaccgaagcc aaggaaaggc cacatggtat tttgccgacg
     8401 agttccattt gcttttgaaa gaggaacaga cggcggccta ttctgcggag atttggaagc
     8461 ggtttaggaa atggggcggc attccaacag gtgccaccca gaacgtcaaa gacctgcttt
     8521 cctccccgga aattgaaaat atccttgaaa acagcgactt cattacgctg ctcaatcagg
     8581 cgtccgggga tagaaaaatc cttgcggaac gcttgaattt gtccaccgaa cagcagaagt
     8641 acatcgacaa ttccgaaccc ggcgagggcc ttttgatctt tgaaaacgtg gtgctgccct
     8701 ttaccaaccc catcccgcac aacacccagc tttacaagat tatgacgacc cgcttaaacg
     8761 aggtggcggg agtatgaccc ggcgacgcca caaaggaggt gaaccaccat gaaagagctg
     8821 aaagccaagg cgaaagtgac gcaggccatg acccgcgacg ggctgacgct ggaaaatcag
     8881 gccaccggcg aggtggagaa catttccagc cgggaggccg aacaggattt gtccgcgccg
     8941 gggccgggcg gcaccgccga taagctgctg gaacgggccg acgccatcca tgacggccat
     9001 aaggccaaga aagccgcgaa gcaggccggg gctgtggccg ccgaggggga cgctgccctg
     9061 caccggccat ccgcccggct ccaactgtcg gaggaagaac gggccgaccc ggatttacag
     9121 ccctatatcc gaaaatcgga caaacgggcc gataagctgg ataaggcccg cgccgccatc
     9181 cccaagaagc gcgtcccggt caaggaaacc gtctttgacg aggcaagcgg caaagcaaag
     9241 accgtcctgc actttgacaa acaggacaag gggcctccct ccctgaaacc caatccggca
     9301 ggccgtcctg tttccgaggt ttttctattc ggccacggga aaatccatga agtcgagcat
     9361 gaaaacgtgg gtgtggaggg cggccataag ggggaggaac ttgccgagcg gcaggccgga
     9421 aaagccatcc gcagcaccat ccggcaccac aggctgaaac cctactggga cgcggaaaag
     9481 gccgagcgca ggctattgtc tgccaacgcg gagtatttct accagaaatc tttgcgggat
     9541 aacccggaga tcgcacaggc ggccagcaac cccatttccc ggttctggca gaaacagcag
     9601 atcaagcgcc agtacgccaa ggccgcccgg acagcgggcc agaccgcagg cgcggcggca
     9661 cagggcgcgg ccaagacagc cggggcctcc acgaaagcgg ccaaggccgc agccaaagaa
     9721 agtgaacggg cggcctcctt tgtggcccgc cactggaaag gggcgctggc cgtccttgtg
     9781 ttggggcttt tgatgctgct tatcatcggc ggcttacagt cctgcaccgc catgttcggc
     9841 agcgccggaa gcggcatcac ggcgtcctct tacttttccg aggatagcga tatgttggcc
     9901 gccgaggacg cctacgcgga gctggaagcc gagctgcaag actatctgga caactacgag
     9961 gccacccatg actatgacga ataccatttt gaccttgacg agatcagcca tgacccctat
    10021 gtgctgattt ccattctgtc ggcgctccat gacgggatat ttaccatcgg ggaggtacag
    10081 ggtgatttgt ccatgctctt tgacaagcaa tatatcctga cagaaaacgt cgtggtagaa
    10141 acccgttacc gcaccgaaac cgatacatgg acggacgcgg agggcaacac ccatacagac
    10201 acctaccaag tgccgtatga ctattacatc tgctacgtca cgctggaaaa cttcgacctg
    10261 tcccatgtgc cagtctatat catggacgag gaaacgctaa gtttctattc cctgtatatg
    10321 tccacgctag gaaaccggcc tgatctgttt tccggcagcc agtaccccaa cgcctccacc
    10381 ctgacgccgc cgacctacta cgacgtaccc ccggaggctt tggaggatgc cacctttgcc
    10441 gccatgctca aagaggcgga aaaatatatc ggttatccct atgtgtgggg cggcagctct
    10501 cccagcacca gctttgattg cagcggcttc atttcgtggg taatcaatca tagtggatgg
    10561 aacgtgggac ggctgggggc gcagggccta tataacatct gcacccctgt ttccagttcg
    10621 caggccaagc ccggcgacct tgtatttttc aagggaacct acgacacccc cggcgtgtcc
    10681 cacgtcggcc tgtatgtggg caacaatgtg atgctgcatt gcgggaaccc gatttcctac
    10741 acgaacctta cttcaaacta ctggcaatcc catttttaca gttacgggcg tttaccttaa
    10801 cgccagaaag gagctttcaa ttatggcaac caaacttgac cgcatcgaaa aggacatcca
    10861 gaaaaccaag tctaagatcg cggagtttca gaaacagctt cgggagctgg aaacgcagaa
    10921 aaccgaacag gagaatttgc agatcatcca gcttgtgcgc ggcatgaaca tgaagccgga
    10981 ggaatttgcc gcgttcttac gcagcggcgc aatgcaggcc gcccctgccg caacccctta
    11041 ccatgaacag gaggacaatg cccatgaaga ataagaccag acggatttcc cgtattctcc
    11101 ccgcacttct ggccgtgatg ctctgcgtca cggcctttcc cgttaccgcc cttgcaggcg
    11161 gcaatgaccc ggcaccggcc ccgctgccgg aggctacaac cgaacccgct acgggcggtt
    11221 tggagcctga aacagacgaa accggcaccg ccacggacgg gacagaaacc gaggccgaaa
    11281 aagataccgg ccctctgacc ggcaaggaca tcaccgacct gttttccgcg ctgttcggtt
    11341 ccaaggtgag cattgccgcc acggacgacg gcatccagat caccaccggc accgacaaaa
    11401 aagaacctga acagaccggc accgtcacca ccaacggcgg caggctgaat gtccgcaccg
    11461 gcgcggggct tgacaagacc gcgttcaccc agcttcccaa tgggacgacg gttgaggtag
    11521 tcggcacaga cggcgactgg attaaaattc tcttgccgga gcgcatcggc tatgtccatt
    11581 ccgactatat gaccgtcagc gaaaaggaag tagcggctac cggcgagggc ggtttttccc
    11641 tctccattga cccggaggaa attgcttctc tgctggaact gttcaatggc ggcggggcca
    11701 gcgccgccct gtccccggac gggaacctgt cactgattga cgacatcggc agcgccgcga
    11761 aaaatggcaa gcagtttatc accgtggaaa ccaaaaacgg caatgtgttt tatctgatta
    11821 ttgaccggga cgacgaggga aaagaaactg tccatttctt aaatcaggtg gatgaagccg
    11881 atctgctgac gctgatggag gacggggaaa ccgtcacccc cgctgctgtc tgctcctgta
    11941 ccacgaaatg caaggccggg gctgtgaaca cgaattgccc ggtatgtaaa accaacctga
    12001 ccgagtgcag cggcccggag ccgcaggaac cccagccgga ggaacccgaa gccccggagg
    12061 aagaacccaa gggcggcgcg ggcggcctga tcgtgttcct gctggtggcg ctggcgggcg
    12121 gcggtgcggc cctttactat ttcaagttca aaaagcccaa ggctgaaacc accggcagcg
    12181 acgatttggg cgagtatgat tttggggagg acgaggattt ggaggacgag gaacccgaaa
    12241 ccgagtttga cccggaagct gattttgtga gtgaacagga ggacgaggaa tgacatataa
    12301 acttgtaatc gcggaaaaac ccagcgtggc ccgcagcatt gcgggcgtga tcggggccac
    12361 ggagaaacac gacggctatt tggaggggaa cggctatctg gtgagctggt gcatcggaca
    12421 tctggtgtcc tttgccgacg ccggacgcta tgacgagcgt ttcaaaaaat ggcgctatga
    12481 ggatttgccc attctcccgg aaacatggca gtacatcgtc cccgacgaca agaaacagca
    12541 gtttgacgtt ctctgttcgc tgatgcagcg ccccgacgtg accggccttg tgtgcgccac
    12601 cgacgccggg cgcgaggggg aattgatttt ccgtttcgtc taccagatgg cgggatgcca
    12661 aaagcccttt gagcgccttt ggatttcctc tatggaggac agtgctatta aggacggctt
    12721 tgcccacctg aaaccgggcg gcgactatga tccgctgtat caatcggccc tgtgccgggc
    12781 caaggccgac tggctgatcg gcattaacgc cacccggctt ttttccgtcc tgtaccacaa
    12841 gaacctgact gtgggccgcg tccagacgcc gaccttaaaa atgctggtgg acagggacgc
    12901 caagattacc gatttcaaga aagagaaata tcacatcgtc catatcacgg cgggcggcgc
    12961 ggacgcggta agcagccgct tttccgacgc tgccgaggca aacaccgtca aggcggcttg
    13021 tgcaaaagcg caggccgttt gcgtttccgt gacgcgggag aaaaagacgg aacagccgcc
    13081 caagctctat gaccttacca ccttgcagcg ggaggctaac cggcttttcg gctataccgc
    13141 caagcagacc cttgactatg cccaggcact gtatctaaag aagctgctga cctatccgag
    13201 aacggatagt caatatctta ccgacgatat gctgcccgcc gtggaaagcc ttgtgtccgg
    13261 cctgtgggag ctggtgccgt ttgccaaggg cctgaacctt tccccgcagt ttgaccgcat
    13321 cctgaacagc aaaaaggtgt ccgaccacca cgccattatc cccaccgctg aatttgtgaa
    13381 gcagggcttt ggcactctgg ccgagagtga aaaaaagctg ctgtccctga tctgctgcaa
    13441 gctcttatgt gccgtggccg ggccgcatat ctatgaggcc gtcaccgcca catttacctg
    13501 tgccgggcag gagtttaccg ccaagggcaa gaccgtcctt tcccccggct ggaaagagat
    13561 tgaacgccgg ttccgttctt ccttaaagac cgacgccgac gaggacgccg aggcggtgcg
    13621 ggagctgccg gagctttgcg agggccagac ctttgcagac gtggccgcct ctgtcaccga
    13681 gcatttcacc acgccgccca agccctacac cgaagatacg cttttgtccg ctatggaacg
    13741 ggccggggcc gaggatatgc cggaggatgc cgagcgcaag ggattaggca caccggccac
    13801 ccgcgccgcc attctggaaa agctggtgca gatgggcttt gtccagagaa aaggcaagca
    13861 gctcattccc accaaggacg gcatcaatct ggctgtggtg ctgccggagg cgcttacttc
    13921 tccccagctt actgccgaat gggaaaaccg gctgaccgag atcgccaagg ggcaggccga
    13981 tcctgacgaa tttatggacg gcatcgagac gcaggcgcgg gagctggtgc agacctattc
    14041 ctgtatcagt gaggaaaagc agaaattgtt tcaggccgag cgtgttccta tcgggacgtg
    14101 tccccgctgt ggtgaggctg tctatgaggg caagaaaaac tactactgcg gaaaccgggc
    14161 ctgccagttc gtcatgtgga agaatgaccg attttttgag gaacgcaaga aagcgttcac
    14221 cccgaagatc gccgctgcgc tgctcaaaac cggcaaagtc aaggtaaagg gcctctattc
    14281 cgtaaagacc ggcaaaacct acgacgggac ggtgcttttg gctgataccg ggggcaagta
    14341 cgtcaactac cgcattgaac acaggagcta aaggacagta acacagcaag catagggagt
    14401 gtggctacac tcccggtaaa atcccccggc cgcgtccctg ccgggccggg gatttttgct
    14461 tgttggggaa gtccccaacc ccctattttt tgaaacagaa cagagaaagg agtgaccgcg
    14521 tgaacgaagt attttctatc caagtccata accggcagtt tttggaacag ggcaaacaag
    14581 gcgtctggct ggatttgccc accacaaccg aaacgctgca agccgccctg cgggatgttg
    14641 gcattactgc cgacaatccg caggattttt ttatcaacgg gtattcctgc ccggaggaca
    14701 gacaccttgc cattccctat gacatggtgc tggccgccga cgtggacgag ctgaatttcc
    14761 ttgccgcccg gctgggccag cttgacgccg ccgagatcgc agagctgaac gccgccctgc
    14821 aaaatccccg tggcggcttt gagaatatcg gccagatcat cgactacacc gaaaatgtgg
    14881 attactatgt gcatcttccc gacgttaggg gggatggaca gttgggcgac tactacctga
    14941 accgttccgg catggtggat atgccggagg aatggaaagc cgggattgat acggcgcagt
    15001 ttggacgcca cattgcccag caggaacaag gcgtttttac ccagtacggc tatctggtga
    15061 gaagcggcga cgaatggcag cgcgtccatg agggccagcc ggtgccggag gaataccggg
    15121 tgatgcacta cccccagccg gaagctgacc gggaggaacc gcaggcccag cagccggagg
    15181 catccgaaag ccccgacaaa gcgccgcccc cggttatccc gatcatgctg gacggcatga
    15241 acagcaaaga acgcatgaaa gtgattactg accgtctgga aaccggcgta caggagcttt
    15301 ttgaaagtag ccgctatatg gcttacttat ccgctatgtc caagatgcac gattacagtc
    15361 tgaacaatac gctgctgatc gccatgcagg gcggttcgat tgtggcgggc tataacaggt
    15421 ggcaggatga atttgaccgc catgtgaagc ggggcgagaa aggcattaag atactggccc
    15481 cggccccgtt caaggttaag cagcagatgg agaaaatcga cccggccacc cagcagcccg
    15541 tgatcggcgc ggacggcaag cccgtgaccg aagaacagga agtgacggtt ccggccttta
    15601 aggtggtgac agtctttgac atcagccaga ccgagggcaa ggattttccc atgccctata
    15661 tcagtgaact taccggcgac gtgcagcagt atcaggattt ctttgccgcg ctggaacgga
    15721 catcacccta tcccataagc attgagccga tttcagacgg ggccaagggc cgctgcttct
    15781 acgcaaaaca gcgcattgcc atcaacgagg gcatgagcga attgcagacc ctaaagaccg
    15841 ccatccatga gattgcccat gccaagctcc acgccattga ccgggaggcc cccgccgagg
    15901 aacaggcggc ccggccagac cgcagcaccc gcgaggtaca ggccgaaagc gtggcctata
    15961 ccgtctgcca gtattacggg ctggacacgt cggactattc ttttggctat gtggccgatt
    16021 ggagcagcgg cagggagtta tccgagctga aagcctccct tgaaaccatc cgggccacgg
    16081 ccagcgaatt gataaccgag atcgacggcc attttgccca gcttcagcag gagcgcgagg
    16141 cccggcagga acaggaggcc gtcacggttg acgttacccc ggaggcagcg gccccggcgc
    16201 aggccgagga agaacaggcc ccggcccttg atccggcagc cgagccgctt gtgactgtgc
    16261 tatggagcga aagcccccag ctaaaggacg gccagcaaat gccgttgcat gaggccgacg
    16321 cgctgtttgc ccgtctggat gcagcatatc cggcagaggc aggctatgac aaaaccgcgt
    16381 tccgcattga ctgtatcttt cagggcgagc cggacagcta cgaggggcgg caggattttg
    16441 gagataggga cggttccctg atcgaacata tccagagcta ccaccaattt tacgcgcagg
    16501 acgaaaactg gaaaaagcat gtaatcgcta caaccggcat agagggctgg gagcaggaca
    16561 aggcccatcg ggatatgctg ttaggcgagt ttgtccccta tatgaagctg cattgcagcc
    16621 ttgcccaaat ggaacagacg gcgcagggcc gcttacagtc cggggaaacc ctgacgccgg
    16681 aggaaacggc ctatttgggg gcgcttctct cttatgtgca ggagtgccgc cccatgctca
    16741 atcagggcca gtatcagttg ccggagccgc cgaaactggc tgacttcgac cagagcttgc
    16801 aggactacaa agcacaggta caggccgaga tcgcgcagga ggccgccgca gccggtatga
    16861 ccgtggagga atacgcggcg gctggctatg aagcacccca acaggacacc ttttccatct
    16921 accagcttcg aggcggggag gaaacccgcg actatcggtt tgagccatac gagcgtttac
    16981 aggccgcagg gctggccgtg gacagtgcca actatgacct tgtttatacg gcaccgctgg
    17041 ataaaagcac gtctttggag gatatttacc gcacattcaa catcgaccac ccggcagatt
    17101 ttaggggaca cagcctttcc gtttccgacg tggtggtgct gcaccagaat ggacaggaca
    17161 ccgcccacta tgtagacagc ttcggctata tggaagtgcc ggagtttttg cgggaaaatc
    17221 ccctgcgtac cgccgaactg tctacggagc agaacgaaaa catgattgac ggcattatca
    17281 acaatacgcc gcccgaaccg cagccggagg aacccgaaca gctatctttt gaggatgtgg
    17341 cagttgcttc cggccagaca caggaggaac ccccggaggc tgcgcccccg caaacggctg
    17401 tccgctatta tcccatcaat gagggagccg cccgccgcgc caaggaagcc atgagctttt
    17461 ctgactaccg gcccggcagc gccacggcgg aataccggca ctatgtcgat caggccgtgg
    17521 aaattgcgga gcgccagaaa aagcgtgtgg agccagagta tcacgaaaag atagacagcc
    17581 tccttgacac ctacgcccgc aagctggccg agaacatgaa taagggctat gagattaccg
    17641 cccgcgtccc ctctgtcctg attgccgggc cgtccaattt cccggtacgg gcgaaagaaa
    17701 agcagaacgc cgccagtgac cgcaacatgg aggaatttca gtacattcag ggcttgcttg
    17761 acaaaatccg cagcaccggc atgggtggta tcagcgccga cgatccgcag gccgtttcca
    17821 agctggaaaa gaaactggaa aagctggaag cgtcgcagga gttgatgaag gccgtcaatg
    17881 cctactaccg caagcatggg acgctggacg gatgccccca tctgaccgaa agaggcattg
    17941 aaaacctgaa agcggatatg gcgtcgggct ggcactatga gaaaaaaccg ttccagtcct
    18001 ggcagctccc caacaataac gccgagatac gccggttaaa gggccgcatt gaggaattga
    18061 cccgccaaaa ggaggcggcc tatgtgggat gggagtttga cggcggcact gtggagatca
    18121 accgggtggc caaccgcctg caaatcttct ttgaggggaa gccggatgct gctgtacgcg
    18181 acgagctgaa aagcaacggt ttccgctggt cgcccaaggc cggggcatgg cagcggcagt
    18241 taaacgacac cacaatccgc gtcgctgacc gtatcaagtg catccagccc ctttccggcg
    18301 aaaagcccag cgccttacag cttgcggccc gcagggagaa agaaaagccc tctatccggg
    18361 cgcagctcaa cgcggccaag accgaacagg ccaagcagcc accggcgcgg gaaaaatcaa
    18421 agggattgga ggtagagtaa atgcagaagt ttgaaaatgt ggacgttctg gccgcgctgg
    18481 aacagatcat gcggcagaac accgcgtttt atcaaagtga ctttggcatt gacaaagaca
    18541 ttatcaggcg ggatgccgcc agcgatcagg ccgcagacaa gaccctgctc tggatgtccc
    18601 ggccctccgg gacgtactgt ttccgggaac gtgatgtttt cctgaaagac acccgacagt
    18661 acaacacatg gaaattttac ggggagcaga cccgtgacaa gatactggcc tacgcggtgg
    18721 agctgaccgg cacacagggc ggcactatcc ggggcaatct ctatgagctg gactatccgc
    18781 agcatttccg gcacgtcatt gaaaccgccc agccggtgag tgtgaaccgg ctcttttatg
    18841 agcatggcac ccgtgacatc ccggagagcc agcgttttga cggaagccct gaccgggtat
    18901 tgggaaactt tttgtactat gaggcccagc cccatgaccc ggctgtgctg caggaggcgc
    18961 tacggacgga gcagcacagc cgggggcggg ccgtccccgg cgatttcaaa gtccacgtca
    19021 ccgctttgca tgacagccgg attgaaaccg aggcccggcg tattgtggac agcctgaaag
    19081 atctgtccgc gcctaacagc cccaataaaa cgcatttcat ggtggagatc tccccgcact
    19141 ttgcggcgat tgcttccacc aaggataatg accggctctt tgccatgctg ccctataaat
    19201 ccctgtgttt taccgggatg aaaggcaggc atggcgtgta tgccgtgatt aaccgggacg
    19261 agcgccggga tgtgagtatt cgcaggcccc ggccctctat ccgcaagcag ctatccgaca
    19321 gcaaacaggc cgccagccca aaaaaggcgg cggccagaac caaaaagaat gaattggagg
    19381 tataaggaat gatgcacttt accgtggagg aagaaaacct gatctgtatg taccacaatg
    19441 cagaccggcg cagaacgata aacaggctca ccgccgtcat gccggttatg gatggggata
    19501 tgcgggcgca ggcccagcag accctttcca agctggaacg catgacggat gccgactatg
    19561 acggccagaa gttccacttc acagacgaat aacgaacagc agacgccggg cgcggcggcc
    19621 atgtggtcgc ttgcgtccgg cgtcttttct ttttgcctat tcctacgcat ttagaacccg
    19681 gtattgtcgg ggataggatg aagtattcgc ttgcccctgc aaacatgcgg gagaagcctt
    19741 gcagcgggcg gttttcaatc ccttaaatgc gtaggttgca gctataatta gacccctgaa
    19801 acagatatag ccgcgcagcg ggtgtatctg tttcaggggt gtgcaggtga tagccgcaaa
    19861 gcggcgtaag agggtgcagc cctcttgccg tctatctctg ttccagcggg aagctcggca
    19921 atgcttccag cagtttcagg gaaatgcgct gccgtatatc ttcgtcaatg actttcttct
    19981 ttttgccgtt tgcctgtctg atctccaccg tggaaagctc gttgatgtag tcagcataat
    20041 gggccaacac tttttccgtg gcccacctct caccggcaac ggcggctttg atcgtttcat
    20101 agtccagcag cttttcttgt ccgtccatcc tgataccccc gtcagactga ttttttctat
    20161 gataccatat tcggaagcat ggaaccagag aaaacggcgc ttttctgctg gtaaattcta
    20221 cgcatttaga acagcacttc ggcggggata ggataaaaca cccacatacc ccgctgacca
    20281 tgccggaaaa gccttgaaat ataagggctt ttacagctct aagtgcgtag gtttccagta
    20341 tcttttccgc tggcgctcgg cctctttgcg gcggcgcatc cgtttggagc aggccgcgca
    20401 gtatttggcc cggttagact tcggcgtgaa cgtggccccg cactcacagc agcgtttcac
    20461 ttcgtcccgg tctttggtga tctcggcata cagggccgca tccagcggga ggacagcggc
    20521 cttaaaccag cggcacagaa gcgaatagga aatgctctgt acgcaaatac attcttcgcc
    20581 gtcgtccagc aacaggcagt tgccgtcaca atagttgcag cactcatgcg tcagcttccg
    20641 ggccttgcga tattgagggt aattcattcg tggaatactc atagctcttg cgtccattcc
    20701 tttcccggcg tcatacgcaa aatgccgtcc acattctgct tgatgatgcc gtattcctgc
    20761 atctgctttt tcgcttcgcc gtacttctca tacagccgtt ccttttcctc ggccaatcgc
    20821 ttgtactcgg ctttcagggc gtacagatcg gggagctttt tcacaccctg tccctttagg
    20881 gcctttgccg cagcttcata caaaatcaac gtgctttcat gctcacgccg gaattttgcc
    20941 ttatccgctg cattgcggta ttccatagcc acgggccaga gctgcttgta ggtagaaata
    21001 ttctttatca gcaccgccat atccgcaagc cggtgttcca tagctttgag ggtagcggcg
    21061 gcctcgtcgc tggcggcggt gatctcggcc actttgcttt ccaaatccgg gtaggtgtct
    21121 atcccatgtt cagtcaggaa attcaaagtc tttgcggcct gcttcaaatt gtggagcttc
    21181 gcccacctct catagcctgc cgactgctgg gccttaatgt tgttttccag atcaatccgc
    21241 aaagaaatcc ccttgcgctc tttgggcgct ctggtgataa cgcggccttt gatacgctct
    21301 ttgatggctt cctcggtgta ggcttccccc aatgtcttgc agcgggtaaa gcgttcctgt
    21361 ccgggagcgc ggaaagaaat aaactttccc ggcttgatct catagccctg cgcctgcatg
    21421 agccgcagga aatcatcaaa atcttttgcc tgcgggatag cggcgtcaat ggctgctttg
    21481 agcttcgctt tccagctcgt ccctttccgc tgggcgtccc actcggcata gctcttgccc
    21541 ttactctggc cgggcttcac cacggacaat ccgttttcct tgcacagcct gtcgctggtg
    21601 cgccggatat aggcatagct ctgtttgttg gaaatgtact tgcgctgatt taccatatcc
    21661 acggcacaga aaataatgtg attgtggacg tggcccttat caatatgggt agtcagcaca
    21721 tagggatatt tcccttgcag cacttcctcg gcaagctgct tcccgatctc atgggcctgt
    21781 tccggcgtgg cttcgccggg ggcaaaggat tgtatcaggt ggtggcccag attattgccc
    21841 ttttggtatg cctgcgccag cagcatttca aattcaatgt ccgctgtttc ataagagcag
    21901 gcaaaggagg ccaccagcag cttgccgtca gttttgtccg ggttctcgat gtagtcaagg
    21961 gcttttttca gcgttgactt gataggatgt atctttgtaa ctgccatatc tgcgccagcg
    22021 ccccctttat atcctcgatg tcctgtgcgt acaccggccc cataccgttc agcctctttg
    22081 caatctgatt gacgttgacg ccgatcttct gtatctcggc ggtctgcgcc cggatgtcgc
    22141 tggtgtccat gttgacgata tagccgtcaa tgagcatctt ccgggcgtag gctgaaaagt
    22201 tcttcgtatg cagcagcgcc attttctgtt caatcatagc ccgttcctcc ggcgtcacag
    22261 ggacgcgcag cacgattttt cgctttctgt ttgccatgct tcaccgtcct ttccattcag
    22321 gggtttgggg atttccccaa caagcaaaac ggacgcggcc cggcagggac ggggcaggcc
    22381 gtttttccgg gagtggctac actccctatg cttgctacgt tactgtttct ccactaacaa
    22441 gacgtttcca aagccccaaa ctacccgcaa aatagccctc tggaaagaaa aaagtgcaaa
    22501 aaaatagaag ctacgctgtg cagctcccgc taaaagtaaa acagaggatg ccagttacac
    22561 atcctccgtt tcattcttct tcggcttttc aattagtatg gcgctgtcaa tcgcgccctc
    22621 gatgatcggc aggtattctt cggggcagag tttcagcttg tggctgaccc tttgccgcag
    22681 ttcgctttcc tcccgcatga tctccgggtt aaagtagcgt tccacaggaa gcccgcaggc
    22741 tttaataagc tgtatgacaa ccggcagact gggaatggcc ccgtcgtttt cgatgttggc
    22801 aagatagcgc cagtcaatat ttattttctc tgccattgct ttgcgcgaaa cgcgctttgc
    22861 ttgccgggcc gctttcacat ccgcgccgaa agtttcaaag ccgggacaat cttcaatatt
    22921 cgccatatcg cacctcccac ttacattgta tatttcatac tctgcccgtg gaatgttggt
    22981 atatgcacct ttcttaaagt ttatatttca cattttgttt cttttattct tcgagcaaaa
    23041 gaattataat gtaccctgtg gaggtgtact atggactaca tgacgttgaa agaggcaggc
    23101 gagaaatggg gtgtgccccc acgatggata aactactatt gtgctgcggg acgcatcccc
    23161 ggcgctgtaa agatggcgac gatctggctc attcccaaaa ctgcggaaaa gccgattgac
    23221 aggcgtacaa agaaaggaaa ggcggttact gaatagtata atgaaaccgg cgcattttgg
    23281 atatggtttt gaagagagag aaagcatggt attttgtcac ggaaaaacta taagatgata
    23341 gatggcaggc tgctccagac cgataaaaag tattctcatc tgaaacagaa agaaaagatt
    23401 tacacatgga tgtatgaaga agcgaaactt tatcatgaca gaaatggaaa atgcccgaaa
    23461 caaagacgag gaagctgctg ctgtatcagc cgtatatggt agaattgaaa aggccggcat
    23521 ctggattctt tatggtgaag tctccagaca ttggataact gctggtctaa tgcgcctttg
    23581 agtatggggt gattgatttt aataccgggg aggtacggct ttttgaggaa aatattctgg
    23641 gatttacatt tggcgattat tacatttcct gtaactgcaa ggacacggat gatgaagata
    23701 tgaggaatat agacttgctg attttctact gtcttgaacg gtattaggac tgaatctgct
    23761 gcgcggagtg cggcaagagc gaccggaggg agtacacaca ggccctgcct gtgtgaaaag
    23821 ccataccgca aggtgcattc gcaaaaaaga ggccgcgcat tttgctgagg cttggggtgt
    23881 ccccaacaag caaaacgaga acgccgcagg cgggcaagtg gtggatcaga atatccgtaa
    23941 aggatattct gatccattgc ttgccagtat tatcgggatg ttttgacaac cgctgtaatc
    24001 gaaacatccc aaacattaag aaggtgttaa ttattattat cttgatttaa ttcgtttaaa
    24061 ccaataatat agatacatac accatgaaaa gaagcgagta tcccaatgac ggatgattaa
    24121 aatccgaaaa gaaatcgctt tgaaactaca gggaaactac agactgttat gttatcttct
    24181 taaaatggag ggatttttat gtcgatacga attctacttg tcgaggatga tgatcatatc
    24241 tgtaatacag taagggcgtt tctggctgag gcaggatatc aggtggatgc ctgcacagat
    24301 ggaaatgagg catacaccaa gttttacgaa aacacttatc aactggttat tcttgatatt
    24361 atgctgcccg gtatgaacgg gcatgaactt ttgcgtgaat ttcgtgcgaa aaatgatact
    24421 cccattctga tgatgacagc cctgtcggat gacgaaaacc aaatccgggc gtttgatgca
    24481 gaggcagacg actatgtaac aaagccattc aagatgcaga ttttactaaa gcgggtggaa
    24541 gccctgctgc ggcgcagcgg tgcgctggca aaggaaatcc gtgtcggcag gctgacactt
    24601 ctgccggagg atttcacggt actttgtgac ggtacagagc tgcccctgac acgaaaagaa
    24661 tttgaaatcc ttttgctgct ggtgcagaac aaaggcagaa ccttaacgca tgaaatcatt
    24721 ttgtcacgta tatggggata tgactttgag ggtgatggca gcacagtcca cactcccaca
    24781 ctcatatcaa aaatttgcgg gccaagctgc cggaaaatat catcaaaacc attcgcggtg
    24841 taggataccg attggaggaa tcataataat ggaaagaaaa gggattttca ttaaggtttt
    24901 ttcctatacg atcattgtcc tgctactgct tgtcggtgta acagcaacac tgtttgcaca
    24961 gcaatttgtg tcttatttca gagtgatgga attacagcaa acagtaaaat cctatcagcc
    25021 attggtggaa ctgattcaga atagcgatag gcttgatatt caagaggtgg cagggctgtt
    25081 tcactacaat aaccaatcct ttgagtttta tattgaagat aaagagggaa gcgtactcta
    25141 tgccacacca aatgccaata catcaaatag ttttagaccc gactttcttt atgtggtaca
    25201 tagagatgat aatatttcga ttgttgctca aagcaaggca ggtgtgggat tgctttatca
    25261 agggctgaca attcggggaa ttgttatgat tgcgataatg gttgtattca gccttttatg
    25321 cgcgtatatc tttgcgcggc aaatgacaac gccgatcaaa gccttagcgg acagtgcgaa
    25381 taaaatggca aacctgaaag atgtaccgcc gccgctggag cgaaaggatg agcttggcgc
    25441 actggctcat gatatgcatt ccatgtatgt caggctgaaa gaaaccatcg caaggctgga
    25501 ggatgaaatc gcaagggaac atgagttgga ggaaacacag cgatatttct ttgcggcagc
    25561 ttctcatgag ctaaaaacgc ccatcgcggc tacaagcgtt ctgttggagg gaatgcttga
    25621 aaatatcggt gactacaaag atcattctaa gtatctgcgc gaatgcatca aaatgatgga
    25681 taggcagggc aaaatcattt ccgaaatact ggagcttgtc agcctgaatg atgggagaat
    25741 cgtacccata gctgaaccgt tggacatagg gcgcacggtt gccgagttgc tgcccgattt
    25801 tcaaaccttg gcagaggcaa acaaccagcg gttcgtcaca gatattccag ccgggcaaat
    25861 tgtcctgtcc gatccgaggc tgctccaaaa ggcactatcc aatgtcatat tgaatgcagt
    25921 tcagaacacg ccgcagggag gcgaggtacg gatatggagt gagcctggtg ctgaaaaatg
    25981 ccgccttttt gttttgaaca tgggcgttca cattgatgat actgcgcttc caaggctgtt
    26041 caccccattc tatcgcattg atcaggcgcg aagcagaaaa agtgggcgaa gcggtttagg
    26101 acttgccatc gtacaaaaaa cgctggatgc catgagcctc cagtatgcgc tggaaaacac
    26161 ctcggatggc gttttgttct ggctggattt accgctcaca tcaacattgt aaatatttaa
    26221 aacttaaatg attttgaccg acaggtataa ccctgccggt ctttttttgc tgctacagga
    26281 aaactacaga ctggctacag ggaaagtaca gatgcgcttg ccataataac aatcgtacca
    26341 gccacaaatc gtagttttat tgcaaaggag gcattcgatc aaatggaaaa aagcaactat
    26401 cattccaatg cggatcatca caaacggcat atgaaacaat ccgtggaaaa gcgggctttt
    26461 ctatgtgcgt tcattatttc gttcacagtc tgcacgctgt ttttggggtg gagactggct
    26521 tccgtattgg aggcaacaca gataccgccc atccctgcaa ctcatacagg cagcagcact
    26581 gacgtagtgg agaatttgga ggaaaacgct cttgccaccg ccaaagaaca gggagatgaa
    26641 caggaatgga gcctgatttt agtgaacagg cagaacccca tccccgcaca gtacgatgtg
    26701 gagcttgagc aactatcaaa tggtgagcgg atagatattc ggatttctcc ctatcttcaa
    26761 gatttgtttg atgccgcaag aactgatgga gtttacccga ttgtcgcatc cggataccga
    26821 acaacagaaa aacagcaaga aattatggat gaaaaaattg ccgaatataa ggcgaaaggc
    26881 tacacctctg cacaggctaa agcggaagca gaaacttggg tggccgtgcc gggaacgagc
    26941 gagcatcagc ttggtcttgc tgtggatatc aatgcggacg gaattcattc aacaggcaac
    27001 gaggtttata gatggctgga tgaaaacagc tatcgttttg gttttattcg tcgctaccca
    27061 ccagacaaga cagagataac cggtgtgagc aacgagccgt ggcattaccg atatgttggc
    27121 atcgaagctg ccacagagat gtacaaccaa ggggtttgcc ttgaggaata tttaaaacca
    27181 gaaaaatgag aaaaggatgt tatgttatgg acagaaaaag attgacacag cgtttcccgt
    27241 tcctgcttcc aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg
    27301 acggctgtcg ctatgcgcag acgatagggg aaaaatcgct ttcccatttg ctctttgaaa
    27361 cggattgcgc attatacaac cacaataccg gatttgacat gatataccag gaaaacaagg
    27421 tgttcaactt aaagctggca gcaaagacct taaacggctt attgataaga ccgggggaaa
    27481 ccttttcttt ctggtggctg gtacgccatg cggacaaaga taccccctat aaagacggcc
    27541 ttacggtgac caatggtaaa ctcaccacca tgtcgggcgg cggtatgtgc cagatgagca
    27601 atttactatt ttggatgttc ctgcatacgc cattgacaat tatccagcgc agaggtcacg
    27661 aagtaaagga gtttccagag ccaaacagtg acgagattaa aggggtggat gcaaccattt
    27721 cagagggctg gattgattta aaagtgcgaa acgataccga ctgcacctac caaatatggg
    27781 tgaccttaga tgatgagaaa atcatcggtc aggtgtccgc cgacaaagag ccccaagcat
    27841 tatacaaaat tacaaatggc agtatccagt atgtccgtga aagtggcggg atttatgaat
    27901 atgcccaggt taaacggatg caagttgcct taggtaccgg ggaaataata gattgcaagc
    27961 tgctttatac aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg gatattcagg
    28021 aggagaacca atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac aggatgaggc
    28081 aaatgctttc cgcgctttat cgccggattt tcatattatc cctacgctga ttagcgatgc
    28141 gatatcggca gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg taggccataa
    28201 gtccgaggtt tccgaggcga caattcttgc gctgagaaag gtcggggtaa aatacatttc
    28261 tacccgcagc atcggctgcg atcacattga tacgactgcc gccgagagaa tgggaatctc
    28321 ggttggcacg gttgcgtatt cgccggacag cgttgcggat tatgctttga tgctgatgct
    28381 gatggccata cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag atttcagatt
    28441 ggatcgtatc cgggggaaag aactggggga tatgactgtg ggagttattg gaaccggcca
    28501 tatcgggcaa gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc tggcctatga
    28561 taacagccga aaaatggatg cagattatgt ccagcttgat gagcttctaa aaaacagcga
    28621 tattgttacg ctccatgtgc cgctttgtgc ggatacccgc catctgatcg gtcagaagca
    28681 aattggagag atgaagcaag gcgcattttt aatcaacacc gggcgcggag cgcttgtcga
    28741 taccggggcg ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg cactggatgt
    28801 gttggagggc gaggatcagt ttgtttatac cgattgctcg cagaaagtgc ttgaccatcc
    28861 ctttttgtcg cagcttttaa ggatgccgaa tgtgatcatc acaccccata cggcgtacta
    28921 cactgagcgt gtgctgcagg atactacaga aaaaacaatc aggaattgtc tcaattttga
    28981 aaggagttta cagcatgaat agaataaaag tcgcaatcat cttcggcggt tgctcggagg
    29041 aacatgatgt gtcggtaaaa tccgcaatag aaattgctgc gaacattgat acggaaaaat
    29101 tcgatccgca ctacatcgga attacaaaaa acggtgtatg gaagctatgc aagaagccat
    29161 gtacggaatg ggaagccgac agtctccccg ccatactctc cccggatagg aaaacgcatg
    29221 ggctgcttgt catgaaagaa agcgaatacg aaacacggcg tattgatgtg gctttcccgg
    29281 ttttgcatgg caaatgcggg gaggatggtg cgatacaggg gctgtttgta ttgtctggta
    29341 tcccctatgt gggctgtgat attcaaagct ccgcagcttg catggacaaa tcactggcct
    29401 acattcttac aaaaaatgcg ggcatcgccg ttcccgaatt tcaaatgatt gataaaggtg
    29461 acaagccgga ggcgggtgcg cttacctacc ctgtctttgt gaagccggca cggtcaggtt
    29521 cgtcctttgg cgtaaccaaa gtaaacggta cggaagaact taacgctgcg atagaagcgg
    29581 caggacaata tgatggaaaa atcttaattg agcaagcgat ttcgggctgt gaggtcgggt
    29641 gtgcggtcat ggggaacgag gatgatttga ttgtcggcga agtggatcaa atccggctga
    29701 gccacggtat cttccgcatc catcaggaaa acgagccgga aaaaggctca gaaaatgcga
    29761 tgattacagt tcccgcagac attccggtcg aggaacgaaa tcgggtgcag gaaacggcaa
    29821 agaaagtata tcgggtgctt ggatgcagag ggcttgcccg tgttgatctt tttttgcagg
    29881 aggatggcgg catcgttcta aatgaggtca ataccctgcc cggttttaca tcgtacagcc
    29941 gctacccacg tatgatggcc gccgcaggaa tcacgcttcc tgcactgatt gacagcctga
    30001 ttacattggc gttaaagagg tgataagtat ggaaaatggt tttttgtttt tagatgaaat
    30061 gttgcatggc gtccgttggg atgccaagta cgccacatgg gataacttca caggaaaacc
    30121 ggtggatggg tatgaggtga atcgcatcat cggcacaaag gccgtggcgt ttgctctgcg
    30181 cgaggcacaa atccatgcgg ctgcgcttgg ctatggcttg cttttatggg atggatatcg
    30241 gccaagaact gcggtggact gcttcctgcg ttgggcagcg caaccggagg acaatctcac
    30301 aaaagaaaaa ttttacccca atatagagcg agccgagttg attacaaagg gttatgtggc
    30361 ctcacaatcc agccatagcc gtggaagcgc aattgatctt acgctctacc acctggatac
    30421 aggggaactt gtttcaatgg gaagtaactt cgattttatg gacgaacggt cgcatcatac
    30481 agcaaaaggg ataggggatg cagaggcaca aaatcgaaga tgcttgcgta aaatcatgga
    30541 aagcagcgga tttcagtctt atcgctttga atggtggcac tataagttga ttgatgagcc
    30601 ataccccgat acctatttta attttgccgt ttcataatga aagtattggt tttgtatcag
    30661 attttggatt tgataaaatc tatgctggtc atggacaatc ttttactgga aagtggttaa
    30721 agcatctttt gtaatacatt gcaaattata gtattcaatc tgcccagcgg cagaaaagaa
    30781 aaaaaccgct gttgggcaga cctttcccac gcccattttg tattttgctg gcggcggttt
    30841 tgagaaatga accgccccct gtcaagtaga cagatgaaaa aagaaaaatt acgccacgag
    30901 ggtctggttc ctgtaagcaa ggggagccag gccctttaac ttagcttgaa gccgccttgt
    30961 attgtaaaag tctatgtatt cgtcgatggc tttcttcaat tcctcgaagg tatgaaattg
    31021 ccggaggtag tacatttcag atttgagaat cccccagaag ccctccatag ggccgttgtc
    31081 gatgcagcgg ccgggccggg acatactctg cgttgcatgg ataccgtcca gctttgcttt
    31141 gaactgccgg ttggtgtact gatagcccct gtcgctgtga aacagaggat gggcgccggg
    31201 gttggctctc accgctctgt caaaggtgtc aaaaacaagc tgattgttgt tggattggcc
    31261 cagtgcatac gcaacgatgc ttttgtcatg gagatcaagg atcgcactca ggtatgcttt
    31321 cttcccattg ataagtttga attctgtgac atctgtcagc catttctcat tgggaccatt
    31381 tgccgtaaat tctctgttca atacgttttc cgcggtaaca cgcggttcta atatgacata
    31441 gtgctttttc tttcggcgta tcacggcctg catatgtaca cttttcatca ggcggtaaat
    31501 ccgcttgtgg ttgtagtttc ttttgagccg gctgttcaca ttcagcgtca tacggcgata
    31561 accgtagatg ccttttactt cgctgtacaa acggatgatt tcttccagca agagggtatt
    31621 ttctttttct gaggcacttt cttcccggtg aagccatttg tagtaagaac agcggggaat
    31681 cccggataac gcgcataacg atgcgatttc atatcctttt tcctgacgaa gcgtatggat
    31741 cgcctcatag accttcctgc ggcgtgtgag cctgtttacc gcctcccctc cagttcgttc
    31801 aattttttta agaaatcgtt ctccatttga agccttctgt tttccgcttc cagctgccgc
    31861 agctttgccg cggctttttc ctcctcgctg tattcggaag gagggcggcg tctcccccgg
    31921 cggtcaagca acccagcttc tccctgctcc tgatattttt tgacccagct atagatctgc
    31981 tgataggtga tcttgtactg ttcgctggtc cgccggtagt ccagttgatg ttctaagcag
    32041 tatagtactg cctgcagctt ttgctcctgc gataattttt ctttctcggc catatctgtt
    32101 tcctcccgcg ctctgcgtgt cttgaactct ctatggcctt gattatacaa cgtaatccat
    32161 tgttgtaaaa ccgcatggga ggaaatcccg tatttgcggc acatggcatc cagcgagcct
    32221 cctccgccca tgtagtcttc tactgccgcc agcttcagtg aggatggata acttgtaaca
    32281 tgctttttcg gatgcagacc cgcaggcccc tccgtctgat atttccgcag ccatgcctgg
    32341 aaagtgctca atcgtatgcc taactcttcc cggatctgtg tggaaccctt acggatcgct
    32401 aggtagtcct ccacagcctg aatctttacc tccggcggta ttttgccttt taaactcatg
    32461 ataattgctc cctccgtttc gacagtttaa tttttttgct gtctacttca gagggagcat
    32521 atcaaaatca aggccgccgt tcttttctgg cagcaaaagg tgtggcggcc cataggagga
    32581 tgccgctatg ctgttttgct attgccatgc tctaatccac ttccaccact caaaaaaagc
    32641 cttgcccctc cacagggcta ttccggttat gagtatgtac tataccatgt aaatcagcag
    32701 catagcaaag cattttctcg cccggtaggt ttgcgacctg ccgggcgatt tttgtcgtct
    32761 tttgcggccc ggctgtcccc aaaaaaattt tttgagaaat tttcaaaaag gaggtattta
    32821 gcgggtagct ggcggccttg tcaaagtctt gttagcggaa agggagagaa ccacctaagt
    32881 cccccacaga aagggggtga gaagatggat gctatccccc gcgactatga agcgcggtgc
    32941 atgttcgatg ctttttgcaa gacggtactg cgtaacgagg ccaaaagcta cttggctgaa
    33001 atgaagcgcc gccgtgaccg tgaagtgtca ctaagctctt tgtcacaggc agatttggac
    33061 aagctctgta cagtagatca ctaccccagc gacagcttta cgttttcgtc gcatggctat
    33121 gacctacata tcaacaatga gcttgttgcc gaagcctttg ccgcgctgcc cagcatggag
    33181 cagagtattt taatcctgca ctgtgttctg gatatggcag atggtgagat cggcggcctt
    33241 gtgggaatgt cccggagtgc cgttcagcgg cacaggacaa ataccttatc ggagctgcgg
    33301 aaacagctaa aggcgttgat gccgaaggga ggttagacgc ggatgaagaa cccgaactac
    33361 aagggcattg agcttttgcc cctttcggtg atcgaggccg cccgcgctgg ggatgccgga
    33421 gccgtagagc gcgttttgca gtattacagc ggttacatga acaagctgtg tacccggacg
    33481 ctctatgacg aaaacggcta tccgcatgtg tgtctggacg aggccatgaa gcgccgtctg
    33541 gaaatcaagc tcatccacgc tatcgtcacg aactgacgaa ccggccccgg cagcatgaaa
    33601 cggcttaccc tttccccgtt tcggtgtttt cccggtggcc tgatcgcacc ttgataaata
    33661 tgcccgcaag ataacggcgg cgcatcatag ggcatacgga cacattctgt ctgtgccgag
    33721 ccggacggct ggtgcgccat gatacttttc cctacgggaa aagcggagcg aggaacacca
    33781 cgccgcaatg tgagcgtggc ggcttgcggg cgacgacgta caggcaggac tatgatactc
    33841 ccttatagcc acagtccgag cgttaaaagc gtcgcaggca atgggtaggg ccgcgtgaga
    33901 accacgcggg ggtgaaagtc ccgtggagct gtgccagcag ccgtccgtct atgcccctaa
    33961 atcacacaaa cctttgaatt tgtgaaaggg ggctgcatta tgaaccatga tgtgcctatt
    34021 tgggaaaaat acacgctgac gattgaggaa gcgtctaaat atttccgtat cggagaaaac
    34081 aaattgcgta agctggccga ggaaaatccg gcctctggct gggtcattat gaatggcaac
    34141 cgcatccaga tcaaacgcaa gcagtttgag aaaataattg acactttgga cacaatctaa
    34201 tagtgaaaaa gggccgcaga tatgttataa taatttataa gcatatatgc ggctctttcc
    34261 gtcatggaaa ggagcatgac gagatgtcag aaaaaagacg agacagcaaa aatcgcgttt
    34321 tgcggtctgg agagagccag agaaaagacg gacgatatgc ttacaaatat gttgatacct
    34381 ttggaaaacc gcagtttgtt tactcatgga agttagtgcc tacggataag accccggcag
    34441 gtaaacggga ggatatttca ctccgggaaa aggagaaaga aatccagaaa gaccttgacg
    34501 acgggataga caccatcggc aagaaaatga ccgtctgcca gctctacgcc aagcagatca
    34561 ggcaccgggg caatgtgaag cacaacacca aactgggccg ggaacggctg atgcgtattc
    34621 tggaacaaga tcggctgggg agctgcccga ttgacagtgt gaagctgtcc gacgcaaagg
    34681 aatgggcgct tcggatgaaa gaaaagggcc tttcttataa gaccatcaat aacgacaagc
    34741 gttccctgaa agcggctttt tacaccgcca tacaggacga ttgcatccga aaaaacccgt
    34801 ttgacttcca gcttagtgac gttctggacg acgatacgga accaaaggtg cctcttacac
    34861 cagcacagga agaaagtttt ctgtccttta ttcaaggtga taaggtttac caaaagcatt
    34921 atgacgcaat cgttattctg ctggggacag ggcttcgcat ttcggaactg tgcggactga
    34981 cggacaaaga tttggatttt gaaaaccggg taatcatcgt gagccaccag cttttgagaa
    35041 ataccggcgt cggttactat attgacgaac ccaagaccca aagcggcgtc agaaaaatcc
    35101 ccatgaatga ggaagtgtat caggcgttcc agcgagtgat aaaaaaccgc aaaggtgcaa
    35161 agccgttcat tattgacggg tatgccaatt tcctgtttct caaacagaac ggctatccca
    35221 tgacggcggt agattatggc gggatgtttg gcaggcttgt gaagaagtac aacaagagcc
    35281 atgaagaagc gttgccgaaa acgacgacgc cccatgctat gcgtcataca ttctgcaccc
    35341 ggttagccaa tgcgggaatg aaccccaaag ccttgcagta cattatggga cattccaata
    35401 tcaccatgac gctgaactat tatgcacacg ccacattcga ttccgcaagg gcagaaatgg
    35461 aacggctggc agcctgacac aaggccggtt ttactactcc atttactact tttgaggggg
    35521 aaatggtgag aggtaataag aacatttgta agtatctaac aatatcaaaa atgccggaaa
    35581 agcccggaaa cacgggctat accgacattc aagaacttct aaaaagataa tctaaaatcc
    35641 catataattt tcctcctaaa aaaatagcac aatggcaaag atcgtaagag agatcataag
    35701 ccccaatgaa tgactaaaaa gaaaagcaga atcacatgcc atatcatccc atatttcttc
    35761 aagaaaataa ataagcggga aaaagggaag gaatagtaga acatcgatcc agcaccattt
    35821 ttttcttctt ttgaaataac ataaaacaat aaacatgaac gtgcagggaa gtaaaaacaa
    35881 agctttactc ataactaaca aaataccagc tccttttatt tttttctccc ccacattcaa
    35941 agagtaacaa tggtatgtac ttaataatag aaaaatggat caacttgtat gaataacagc
    36001 tgaaaagatc tgcaccaaat aaaaaacttc cagccaaaac tgactggaag tttatttttt
    36061 tctgaaatat tctaacacaa atatgaaaaa gatggccgaa gctaataagc cgatttcgta
    36121 gcaaaacaat gagataccag agtcgtaata ataaaatcct ctaatcttat ggataaaata
    36181 gatcatcgga caagcagata agagtaagta tttgttaggc cttttgaata agtaaaagaa
    36241 agcactggtc attatgataa atggtatcca aaacaaaagt ttacttaaga caatcaaatg
    36301 atcaactccc atatttttta ccaagagaga tcataacatc tttatcgtaa aaacaaaata
    36361 tttttttgct cattttgaaa atttaaacat actcgttctt atccaaatat ataaaaatcg
    36421 cccctcattc atcgagaggc gataagttct aatttaactc aatttttttt gtttcttttg
    36481 gctgataagc tgttttaggt aataccaatt tcagcacacc gtttttaaag gttccagtga
    36541 ttttttcttc atcaacatta ggaagataga atgaacgttt gtaagagacc gaatgtcttt
    36601 ctttccgtac atagttgcca tcttctttat cttctgtatg ggactcatga ttggcggaga
    36661 tcgtcaaagt attatctgaa tattcaactg tcgtgtcttc tttgtcacag ccaggcatat
    36721 cagcagttag tttgtattct ttttcatttt cgactaaatc tacttttgga taacttgaaa
    36781 cacctaaaaa atcattgaat gctggactaa acacgtcatt gaaatcaggg aacatgtcgc
    36841 gaatgctagg tacatttgcc atttttgatc atcctttcaa taagtatttt ttatttatcc
    36901 ctatttacgt aataactcta ttttgaaaaa aatgcaagta taatggttag ctttgtgaat
    36961 atttcatcta atacgataca aaggctatct ttctaatttg aaaaagggat cattaaaata
    37021 ataagaagaa aatatgtcaa aaggtaaaaa agtaaattct tctatccaaa tatagaaaaa
    37081 ttgaatctag aaaaccgccc gacaataaat ttcattaact cagttgaccg aaaatgaagt
    37141 agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat aagagaaata
    37201 gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata actttctcag
    37261 aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat catctaatca
    37321 aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca ctcgataaaa
    37381 accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg tgaacaaata
    37441 atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta attcggaacg
    37501 gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag aaggtacagt
    37561 gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg attggctatg
    37621 ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag tacttttagt
    37681 tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat tctttgtttt
    37741 atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa tccctttatg
    37801 catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa acaaagaaaa
    37861 gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga agataataac
    37921 ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa tcattgggaa
    37981 aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct tcgcaaaaat
    38041 agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc ctaccaacag
    38101 ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaaag ttttcattag
    38161 aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca ttgcttatat
    38221 aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg ctcttccatt
    38281 agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt agtgagcttt
    38341 tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt ggttggatat
    38401 tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa gtatcgtcga
    38461 aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat gccgtataca
    38521 gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca tagaagaagg
    38581 gatatataaa gtaatgaaac atttcaagac gatcgatggt ctagtcaata atgcaggaat
    38641 aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg aattatcaga
    38701 acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga tgagccaagc
    38761 agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatgttt cttctgaatc
    38821 aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag cgatgaacag
    38881 ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg taggtgttgc
    38941 accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag ctctttctta
    39001 tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa gtacgatccc
    39061 tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt atctttcaga
    39121 aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa caagaggata
    39181 aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat tgaaattact
    39241 agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa ccagtaatca
    39301 aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg caaaaatcat
    39361 ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg atgagatcat
    39421 gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa tcgcttattt
    39481 actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt ctgaagaagt
    39541 cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga tgatcaatga
    39601 ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag gagatgagct
    39661 agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga cgaaaacaga
    39721 acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga atgctagtaa
    39781 acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa tctctagtaa
    39841 ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata tccaagaatt
    39901 caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc aatatgaaaa
    39961 agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga taaggaaagc
    40021 taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac gattagatct
    40081 cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct ctttattgat
    40141 aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga tagaaaaaaa
    40201 gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag ctatcttgca
    40261 acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt tagcatttcg
    40321 atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga caggaaaagg
    40381 aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata tacaaataac
    40441 acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg ctgtttttac
    40501 aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttga ctaatctttt
    40561 tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat tagccgggtt
    40621 tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc aagaatattt
    40681 aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat ttgaaaaaag
    40741 gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg cttttcctca
    40801 cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa ctgatcaagg
    40861 tttagcagaa acaggaggaa atggagttat ttttttattt gccatacctg aagaaatgac
    40921 ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac tcataaaaat
    40981 gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa aactaatcaa
    41041 aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc gcagcttcag
    41101 cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat caaacatata
    41161 gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa atccgttcag
    41221 gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc agaaaaatgc
    41281 aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt gaagatatcc
    41341 attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca caagcagctt
    41401 tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa agtgaacaac
    41461 cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt acgatcaaag
    41521 aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat ttatgaggct
    41581 gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac cagttgtctt
    41641 gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc gagtaacgaa
    41701 agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac cgttcttatc
    41761 tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc cagaatacta
    41821 caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg gtgtattccc
    41881 ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga tcgaaacctt
    41941 agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc tgatgaactt
    42001 tattggtggt tggataactg attttactac tggatttgta tgcagacagc aaggaatcgt
    42061 tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta aatgtatggt
    42121 gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat taggccgaca
    42181 aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat gatcgtagat
    42241 aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc aatacctgat
    42301 agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg aatttatcct
    42361 aaaaaaggga taccaaccat caatatcgtt tccacaggaa aaagtggccc attagcacaa
    42421 tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca gccactaatg
    42481 gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa gtacaaatat
    42541 gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat agcaaaaatt
    42601 ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga agcagtagat
    42661 acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat tggtgtgata
    42721 caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc aggaaatgca
    42781 gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc tttgcttggt
    42841 ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat tgggaaagga
    42901 aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca aaatgcatgt
    42961 gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt agaagtaggt
    43021 gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat cattgcttgg
    43081 gtagcaagtt ttggattata tagctga
//
LOCUS       DAZKNV010000020        41131 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000020 DAZKNV010000000
VERSION     DAZKNV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.020"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1384
                     /locus_tag="ACG8M1_001186"
     CDS             <1..1384
                     /locus_tag="ACG8M1_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HFQ0421911.1"
                     /translation="SGVAAESQTPAKPAAEPTVDTESAGSSSEGVFQFKLPDIGEGIA
                     EGEIVKWFVKPGDTINEDDTLLEVQNDKSVEEIPSPVTGTVKNVIVPEGTVANVGDVL
                     VEIDAPGHNSAPSTSAPSAEAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKD
                     VDISQVTATGKGGRVTKEDIENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPA
                     KPFKSNLGDLEERVAMTPTRKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEV
                     AAANGTKLTFLPYVVKALTATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLY
                     VPNVKDADRKGMFAIADEINEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVI
                     NYPEVAILGVGTIAQQPIVNAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLL
                     ADPELLMMEG"
     gene            1392..2798
                     /gene="lpdA"
                     /locus_tag="ACG8M1_001187"
     CDS             1392..2798
                     /gene="lpdA"
                     /locus_tag="ACG8M1_001187"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFQ0421912.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEITILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2960..3235
                     /locus_tag="ACG8M1_001188"
     CDS             2960..3235
                     /locus_tag="ACG8M1_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFQ0421913.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3241..4008
                     /locus_tag="ACG8M1_001189"
     CDS             3241..4008
                     /locus_tag="ACG8M1_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFQ0421914.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            4176..6005
                     /gene="typA"
                     /locus_tag="ACG8M1_001190"
     CDS             4176..6005
                     /gene="typA"
                     /locus_tag="ACG8M1_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFQ0421915.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6266..8038
                     /gene="recQ"
                     /locus_tag="ACG8M1_001191"
     CDS             6266..8038
                     /gene="recQ"
                     /locus_tag="ACG8M1_001191"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFQ0421916.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            8152..8454
                     /locus_tag="ACG8M1_001192"
     CDS             8152..8454
                     /locus_tag="ACG8M1_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFQ0421917.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8457..9620
                     /locus_tag="ACG8M1_001193"
     CDS             8457..9620
                     /locus_tag="ACG8M1_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0421918.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9646..13074
                     /locus_tag="ACG8M1_001194"
     CDS             9646..13074
                     /locus_tag="ACG8M1_001194"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFQ0421919.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISPGDLLIEVTEK"
     gene            13095..14219
                     /locus_tag="ACG8M1_001195"
     CDS             13095..14219
                     /locus_tag="ACG8M1_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFQ0421920.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            14200..14646
                     /locus_tag="ACG8M1_001196"
     CDS             14200..14646
                     /locus_tag="ACG8M1_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0421921.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14630..14968
                     /locus_tag="ACG8M1_001197"
     CDS             14630..14968
                     /locus_tag="ACG8M1_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFQ0421922.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            15087..15647
                     /gene="rsmD"
                     /locus_tag="ACG8M1_001198"
     CDS             15087..15647
                     /gene="rsmD"
                     /locus_tag="ACG8M1_001198"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFQ0421923.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15644..16135
                     /gene="coaD"
                     /locus_tag="ACG8M1_001199"
     CDS             15644..16135
                     /gene="coaD"
                     /locus_tag="ACG8M1_001199"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFQ0421924.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            16125..17168
                     /locus_tag="ACG8M1_001200"
     CDS             16125..17168
                     /locus_tag="ACG8M1_001200"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFQ0421925.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17327..18055
                     /locus_tag="ACG8M1_001201"
     CDS             17327..18055
                     /locus_tag="ACG8M1_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFQ0421926.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            18171..18416
                     /locus_tag="ACG8M1_001202"
     CDS             18171..18416
                     /locus_tag="ACG8M1_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0421927.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18413..18631
                     /locus_tag="ACG8M1_001203"
     CDS             18413..18631
                     /locus_tag="ACG8M1_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFQ0421928.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18767..19306
                     /locus_tag="ACG8M1_001204"
     CDS             18767..19306
                     /locus_tag="ACG8M1_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFQ0421929.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19299..21572
                     /locus_tag="ACG8M1_001205"
     CDS             19299..21572
                     /locus_tag="ACG8M1_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFQ0421930.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21610..22656
                     /gene="holA"
                     /locus_tag="ACG8M1_001206"
     CDS             21610..22656
                     /gene="holA"
                     /locus_tag="ACG8M1_001206"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFQ0421931.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22745..22999)
                     /gene="rpsT"
                     /locus_tag="ACG8M1_001207"
     CDS             complement(22745..22999)
                     /gene="rpsT"
                     /locus_tag="ACG8M1_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFQ0421932.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23389..23667)
                     /locus_tag="ACG8M1_001208"
     CDS             complement(23389..23667)
                     /locus_tag="ACG8M1_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421933.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPECLY"
     gene            complement(23929..24057)
                     /locus_tag="ACG8M1_001209"
     CDS             complement(23929..24057)
                     /locus_tag="ACG8M1_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421934.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(24137..24592)
                     /locus_tag="ACG8M1_001210"
     CDS             complement(24137..24592)
                     /locus_tag="ACG8M1_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFQ0421935.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24730..26658)
                     /locus_tag="ACG8M1_001211"
     CDS             complement(24730..26658)
                     /locus_tag="ACG8M1_001211"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0421936.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26855..27688)
                     /locus_tag="ACG8M1_001212"
     CDS             complement(26855..27688)
                     /locus_tag="ACG8M1_001212"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFQ0421937.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27880..28584)
                     /locus_tag="ACG8M1_001213"
     CDS             complement(27880..28584)
                     /locus_tag="ACG8M1_001213"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0421938.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28607..29233)
                     /locus_tag="ACG8M1_001214"
     CDS             complement(28607..29233)
                     /locus_tag="ACG8M1_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0421939.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29559..31934
                     /locus_tag="ACG8M1_001215"
     CDS             29559..31934
                     /locus_tag="ACG8M1_001215"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFQ0421940.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31958..32449)
                     /locus_tag="ACG8M1_001216"
     CDS             complement(31958..32449)
                     /locus_tag="ACG8M1_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFQ0421941.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32636..33556
                     /locus_tag="ACG8M1_001217"
     CDS             32636..33556
                     /locus_tag="ACG8M1_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0421942.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33710..34054
                     /locus_tag="ACG8M1_001218"
     CDS             33710..34054
                     /locus_tag="ACG8M1_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFQ0421943.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34244..34744)
                     /locus_tag="ACG8M1_001219"
     CDS             complement(34244..34744)
                     /locus_tag="ACG8M1_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0421944.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35272..35355
                     /locus_tag="ACG8M1_001220"
     tRNA            35272..35355
                     /locus_tag="ACG8M1_001220"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35306..35308,aa:Leu,seq:cag)
     gene            complement(35679..36317)
                     /locus_tag="ACG8M1_001221"
     CDS             complement(35679..36317)
                     /locus_tag="ACG8M1_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0421945.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            36652..37086
                     /locus_tag="ACG8M1_001222"
     CDS             36652..37086
                     /locus_tag="ACG8M1_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0421946.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            37109..37429
                     /locus_tag="ACG8M1_001223"
     CDS             37109..37429
                     /locus_tag="ACG8M1_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421947.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            37570..37761
                     /locus_tag="ACG8M1_001224"
     CDS             37570..37761
                     /locus_tag="ACG8M1_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421948.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(37832..38089)
                     /locus_tag="ACG8M1_001225"
     CDS             complement(37832..38089)
                     /locus_tag="ACG8M1_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFQ0421949.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            38247..38510
                     /locus_tag="ACG8M1_001226"
     CDS             38247..38510
                     /locus_tag="ACG8M1_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421950.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            38534..38722
                     /locus_tag="ACG8M1_001227"
     CDS             38534..38722
                     /locus_tag="ACG8M1_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421951.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(38805..38990)
                     /locus_tag="ACG8M1_001228"
     CDS             complement(38805..38990)
                     /locus_tag="ACG8M1_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421952.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            39205..39576
                     /locus_tag="ACG8M1_001229"
     CDS             39205..39576
                     /locus_tag="ACG8M1_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0421953.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(39726..39798)
                     /locus_tag="ACG8M1_001230"
     tRNA            complement(39726..39798)
                     /locus_tag="ACG8M1_001230"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39763..39765),aa:Gln,seq:ctg)
     gene            complement(39844..40272)
                     /locus_tag="ACG8M1_001231"
     CDS             complement(39844..40272)
                     /locus_tag="ACG8M1_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421954.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(40332..41090)
                     /locus_tag="ACG8M1_001232"
     CDS             complement(40332..41090)
                     /locus_tag="ACG8M1_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0421955.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT        13701 a         7095 c         8439 g        11896 t
ORIGIN      
        1 cagtggtgta gccgcagaat cccaaactcc agctaaaccg gctgctgaac ccactgttga
       61 tacagaatca gctggatcgt caagcgaagg agtcttccaa tttaagttac cggatatcgg
      121 tgaaggaatc gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa
      181 tgaagatgat acattactag aagttcaaaa tgacaaatca gtagaagaaa ttccgtcacc
      241 tgtcacaggg acagttaaaa acgtgattgt tccagaaggc actgtagcaa atgttgggga
      301 tgtattagta gaaatcgatg ctcctggaca caatagtgca ccgtcaacta gtgcgccatc
      361 agctgaagca ccaaaagaaa aagtggaaac atcaggttca gcaagtgtcg ttgaagctgc
      421 cgatccaaat aaacgtgtat tggctatgcc atctgttcgt caatttgccc gtgaaaaaga
      481 tgtagatatc tcacaagtaa ctgcaactgg aaaaggtggc agagtaacaa aagaggacat
      541 cgaaaacttc ttggcaggtg gtccaagcag tgcaccagcg aaatcagaag cgccagaagc
      601 ggcagcaccg aaagaagcag ctcctgcagc agaaagcaaa ccagctgcac cagcaaaacc
      661 attcaagtcc aacttaggag acttggaaga acgtgtagca atgacgccaa cacgtaaagc
      721 tatcgctaaa gcaatggtca acagtaagca tacagctcca cacgtgacat tgcatgatga
      781 agtagaagtg tctaaactat gggataatcg gaaacgattt aaagaagttg ctgctgcaaa
      841 tggtacgaaa cttactttct tgccatatgt cgtgaaagct ttaacagcga ctgttaagaa
      901 atacccagta ttgaatgcat ctatcgacga tgcaaaccaa gaaatcgttt ataaacatta
      961 ctacaatatc ggtattgcaa ctgatacgga tcacggacta tatgtaccaa atgtgaaaga
     1021 tgcagaccgc aaaggaatgt ttgctattgc agacgaaatc aatgagaaag caaaattagc
     1081 tcatgacggc aaactatctg cagaagatat gcgcaatgga acaattacga tcagcaatat
     1141 cggatctgta ggtggcggtt ggtttacacc agtcatcaac tatccagaag tagctatttt
     1201 aggtgtagga acgattgcac aacaaccaat cgtaaatgct gaaggcgaaa tcgttgtcgg
     1261 tcgtgtgatg aaactgtcat taagtttcga tcaccgtatc gtagatggag caactgcgca
     1321 acaagcaatg aataatatca aacgtctttt agctgatcca gagctattaa tgatggaagg
     1381 atgataaaca aatggtagtt ggagattttg ctgtagaatt agatacagtt gtaattggtg
     1441 cgggacctgg tggctatgta gctgccatcc gcgctgctga aatgggacaa aaagtagcaa
     1501 tcattgaaag agagtatatt ggcggtgttt gtttgaatgt cggctgtatt ccttcaaaag
     1561 cactgatagc tgcaggacac cattatcaag agtcactaga ttctgaaatg tttggagtaa
     1621 ctagtgaaaa cgtcaaacta gattttgcaa aaacacaaga atggaaagaa aacaaagttg
     1681 tccatacgtt gacttctggt gttggtttcc tattaaaaaa acataaggtt gaaacaatcg
     1741 aaggagaagc gttcttcgta gatgatcaca cactacgcgt cattcatcca gattcagctc
     1801 aaacttattc gttcaataac gcaatcatcg caacaggttc ccgtccaatc gagattccag
     1861 gatttaaatt cggaggacgt gtgttagatt ctactggcgg attagcattg aaagaagtac
     1921 ctaagaaatt tgtgatcatc ggtggcggtg tgattggtgc cgaattgggc ggagcgtacg
     1981 caaacttagg agcagaaata acgattcttg aaggctcacc acaaatttta ccaacttacg
     2041 aaaaagatct agtaaaatta gtagaagatg atttcaagaa aaaaggcgta acagtcgtaa
     2101 cgaatgcaat ggcgaaagaa gcagtcgata acggtgacag cgtgacagtg aaatatgcag
     2161 tggacgggaa agaagaatcc gttactgctg attatgtgat ggtcactgta ggtcgtcgtc
     2221 cgaatacaga tgatatgggc ttagaacaag cgggtgtcga agtaggagaa cgaggattga
     2281 tcacggtgga taaacaagga cgtacgaacg tacctaacat ctatgccatc ggtgatatcg
     2341 ttccaggggc ggcattagca cacaaagcca gttatgaagc aaaaatcgct gctgaagcaa
     2401 tctctggcaa aaaagtagct gtagattata aagcaatgcc ggcagtagcc ttcactgatc
     2461 ctgaattggc ttctgtaggt atgacgatca aagaagcaaa agatgctggt atcgaagcaa
     2521 aagcatataa attcccattt tcagggaacg gtcgggcatt atcgcttggt aaaacagaag
     2581 gattcatccg tctagttacg acgatcgaag ataacgtgct tattggcgcg caaatcggtg
     2641 gagtcggcgc aagtgatatg gtctctgaat tagctttagc aatcgaatca ggaatgaatg
     2701 ctgaagatat cgccttgacg attcatcctc atccatctct tggcgaaatc gtcatggatg
     2761 cttcggaatt agcattaggt ttaccaatcc atatttgatt tgaataatac aggcgaaacg
     2821 caactgaaaa atcagttgcg ttttgttttt tagaattatc aataatatta ttatgtaaac
     2881 ttaaaaatat gacaacttct tggtttatta ccacttccta tgctacactg aagaggaata
     2941 tgaaatagga gagttgaaga tgcaagaata tcagtatcca cttgatttag attggacaac
     3001 agacgaaatg gtcattgtaa tgaagatgtg ggaagatctg gaacgtgcga atgaaaaagg
     3061 gataaacaat gaagcttttt tgaagactta tcagcagttt aaaactgttg tcaaatccat
     3121 tggtgaggaa aaacgattgg gacgggaatt tgaaaaagct tccggttatt ctttatatcg
     3181 tacagtgcag caagcaaaaa aaaatccaaa caaaactttg agaatgaacg ggtgagataa
     3241 atggaacaga tgattgatca tatcaagtcc tggcttgaag aagctggtga gaaaatcaaa
     3301 tcttctcaac aaacattaac aatctcgcaa aaatcaaatc gaacggatct agtaacaaat
     3361 gtcgatcgaa acatccagaa ttttctaatc gaaaaaatcc attcctttga tccagaggcg
     3421 aaaatattgg cagaagaaga agggtgtaat caattatcgg atctcgatgg aagagtcttt
     3481 atcatcgatc ctattgatgg caccttgaat tttgtgattg aaggggaaaa tttttgtatt
     3541 atgctcgctg tttatgaatc cggcgttgga aagcttggtt tcatttatga cgtgatgaga
     3601 aatgaacttt tttggggtgg aaaaggaata ggcgtgtata aaaatgatga gccattgcct
     3661 agaccagcaa ataaatcctt atcggaaggc ttacttggtg tgaatagtta tcttttcggt
     3721 cataataaat atggaatccg agaaattgcg gaaagcagca tggggacacg tatgtacgga
     3781 tgcgctggtc ttgaactagt ggcaatcttg aaaggaaacc acattgctta tatttcaaac
     3841 cttagccctt gggattatgc agcgggaaat gtcttattgg aagagtttgg tatggtaaca
     3901 agcggtcttt ttggtactcc tttgacattt gaaaaaaggg aatactattt agcagggact
     3961 tcttgtgcat atgcagaaat cgcagacctt ttgaaaaaag aaggctgaaa aaaaggtaga
     4021 aatcattcac aaaaatgata aaaacgagca aaagattaat tttctcgaaa aaatgaaaac
     4081 attttactat atttcatgaa aaaagtctgc tataattagc agtcgagtaa aatttgccct
     4141 gtcataaaga accaataaaa aaggagttag ttacattgaa ttatagaaac gatatccgta
     4201 acgtcgcaat tattgcccac gttgaccacg gaaaaacaac attagttgat gaactattaa
     4261 aacaatcaga tacattagac gcacatacgc aattgcaaga acgtgcgatg gactcaaatg
     4321 cgctagaaaa agaacgtggt atcacgattt tagccaaaaa cacagctgta gactataaag
     4381 gtattcgcgt aaacatcatg gatactccag gacacgcgga cttcggtggc gaagtagaac
     4441 ggatcatgaa aatggttgac ggcgttgtgt tggtcgtaga tgcgtatgaa ggaacaatgc
     4501 ctcaaacacg ttttgtattg aaaaaagcac tggaacaaca tatcacacca atcgttgtcg
     4561 taaacaagat tgacaaacct tctgctcgtc ctgagcatgt cgtagatgaa gttcttgaac
     4621 tattcatcga attaggagca gatgatgatc agttagactt tcctgtgatt tatgcatctg
     4681 cactaaatgg tacgtcaagc ttgtcagatg atccagcaga tcaagaacca accatggcac
     4741 ctatttttga tacaattatt gaaaaaatcc ctgctcctgt cgataacagc gacgaaccat
     4801 tacaattcca agtttcatta cttgactaca acgattatgt aggtcgtatc ggaatcggac
     4861 gtgtatttag aggaacaatc aaagtaggag accaagtagc attaattaaa ttagacggaa
     4921 cagttaagaa attccgtgta acgaaattat ttggtttctt tggactaaaa cgtctagaga
     4981 ttcaagaagc aaaagctgga gacttgattg ctgtctcagg tatggaagat atctttgtcg
     5041 gtgaaacagt tactcctgtg gatcatcaag atgcgttacc tatccttcac attgacgaac
     5101 caacattgca aatgactttc ttagttaata attcaccatt tgccggtcga gaaggtaaat
     5161 tcgtaaccgc tcgtaagatt gaagaacgtt tgatggcaga acttcaaaca gatgtatcct
     5221 tacgagttga accaacaaac tctccagatg catggacagt ttctggtcgt ggagaattgc
     5281 atttgtctat cttgattgaa aacatgcgcc gtgagggata cgaattgcaa gtatctcgtc
     5341 cagaagttat tgaaaaagaa atcgacggtg taaaatgcga accgtttgaa cgcgtgcaaa
     5401 tcgatacacc agaagaatat atgggtagtg ttatcgagtc cttgagctta cgtaaaggtg
     5461 aaatgcaaga tatggtccat acaggaaacg gacaaatccg tttgacattc ttaacacctg
     5521 cccgcggttt gattggttat tcaactgaat tcctttcaat gacacgtggt tacggaatca
     5581 tgaaccatac ttttgaccaa tatctgccaa tgcttcctgg tcaaattggc ggacgtcacc
     5641 aaggggcgct tgtttcgatc gatacaggaa aagcaacgac ttattctatc atgagtatcg
     5701 aagaacgcgg tacagtcttc gtagaaccag gtacagaagt atatgaagga atgattatcg
     5761 gggaaaacag ccgtgataat gatttgactg tcaacatcac gaaagcaaaa caaatgacaa
     5821 acgtacggtc tgctactaaa gaccaaacat ctgtcatcaa aaaaccaaaa caattgacgt
     5881 tggaagaatc tttggaattc ttgaatgatg atgaatattg cgaagtaaca ccagaaagca
     5941 ttcgcttgag aaaacaaatt ttagagaaaa atgctcgtga aaaagcatct aaaaagaaaa
     6001 aataatctgt aaaaggatga agagagaaac cagcttgtta taaaaaatag ctggtttctt
     6061 tttttgtcca actcttttct gtggagaagt catctttgtc aatggacata aattcagaaa
     6121 atacgccgaa agacgtttaa aagactttta aaaaacttat ttctagagag tttttgtttc
     6181 ataataagat aatgtttcac gaaaggagat caacttgtcc ttcgaagaaa atcgaagtaa
     6241 aatggcaaga gaaaggagcg ggaagatgaa cgacttatta aaacaatact ttggctatga
     6301 tgagtttaga cctggtcaaa aagaaattat ccagaaagtc attgatcagg aaaatgtatt
     6361 aggaatcatg cctaccggaa gtgggaaatc aatctgttac cagcttccag ctttactatt
     6421 agatgggctt actgtggttg tgtccccttt aatctctttg atgaaggatc aggtggacgc
     6481 ggcgaatcaa ttaggtatac ccgccacttt tatcaatagc tcgttagatg gttacgaaac
     6541 agctagacgc ttccaagaaa tcgatagaca gcagtaccgt ttactttata tcgctcctga
     6601 acgttttatc atgccggatt ttatccaagc aatgaagcga tggaacgtcc gtatgatcgc
     6661 tattgacgag gcacattgta tctctcagtg ggggcatgat ttccgcccaa gttatttaca
     6721 gatggcgaac cagctagatc aactgccaaa tcgtcctgta attgttgctt tgacagctac
     6781 agcgactgtg caagtagctg ctgacataaa aagactttta aaaattccag aaaacaacca
     6841 tattcagact ggttttgaac gagaaaatct acgatttcaa gtaattaaag atcaaaaaaa
     6901 agaacaatat ctaatcgaat atttaaagat caacaaaaat caatctggta tcatttatgc
     6961 agcaacgaga aaagaagtag accgtctcta tcatttgctt aaaaaattcg atttttccgt
     7021 gggtagatat catggtggtc taaatgagaa tgagcgaaca gaaatgcaag aagccttttt
     7081 atacgatcgc ttgcagctga ttgtagcgac aaatgcattt ggtatgggta taaataaaag
     7141 caatgtccgt tttgttatcc attatcaaat tcctggctct ctagaagcat actatcagga
     7201 agctggtcgg gcgggaagag atggtctttc cagtgaagcc atcctgcttt tctctcctca
     7261 agatatccaa gtccaaaagt tttttatcca gcagtcccaa agagaagaag ggcaaaagca
     7321 aaaagaatat gaaaaattaa aagcgatgac agaatacgtg tatattgagt cctgtcttca
     7381 gcaatacatc ctaaactatt ttggcgagac aagcagtccg tgcaaccgtt gtggtaactg
     7441 tttagatgac agagaaatag tagaagtaac gacagaagca cagatggttc tttcttgctt
     7501 aaaacgtatg ggtgagaact atggtaaaca aatgctgatg aaagtcttag caggatcgaa
     7561 agaacaaaag ctgcaagctt taggttttgg acatttatct acctatggac tgatgaaaaa
     7621 ccaatcgcaa aaagaaacga tgcagttaat tgaatatttg atatcgaatg gctatcttct
     7681 gaccatcaat ggtgagtatc ctgttttgaa agtaacagaa agagggatac aagtattgaa
     7741 aggacaagaa tctgtttatc gaaaggaacc caagaaagtc cagcagctat cggatgaaga
     7801 aaccgataca ctatttgaag tgctgcggga actgcgaacg gatctagcat cagaagcagg
     7861 cgttcccccg tatgtcgtat tttcagattc cacattgaaa gaaatgagcc gaatacgtcc
     7921 atcaagcaga ttggagatgc ttcagataaa aggagttggc caaagcaagc ttgataaata
     7981 tggcgaagcc tttttatctc ggataaaaaa tgcggactct aacgttctgg ataagtagaa
     8041 agaacgaata cgtaaaaatg aataaaaaca actggttaaa tctgtttttt ttgctcctta
     8101 tgaaaatcaa atatgttata attaaggaat tagaatggga ggtaagcaca gatggattct
     8161 ttgtcgaaaa aacttgcgat ccaagtatta aatgatgaag cagaacggat caaacgatta
     8221 atccgaaatc aaaacaacag tctctgtatc tcacaatgca aagccttcga agaagtggta
     8281 gatacacaga tgtacggctt ttcccggcaa gtcggttttg ctgtccgtat aggagtaatc
     8341 ggaaagaacg agggccagct gatgttaagt gagctagaac gagaattgaa tcagttatat
     8401 agtgaggttt accaagaaat ttatgataaa aaagaagttg gcaaggagga atagacttgc
     8461 ctaagaaagt gaaaaaaagg catctattag actatagcat cttgattccc tatttaattt
     8521 tatgtgtatt gggattgatc atggtatata gttctacgtc gtatctatta ttagaaaacg
     8581 gacaaaatcc gtccgcatca gtcattaacc agagtatttt ttgggtgctt agcttgattg
     8641 ctatcgcact actttataaa atgaaaacag atgttttgaa aaaccagcgt ttgatcatgg
     8701 cagccatcgc agttttgacg attttgctgc tgattgttgt gttttttggt aaggagatca
     8761 atggggcgaa aggttggctg caaattgcag gattctcgat ccaacctgcc gaatacctaa
     8821 aaatcatttc tatctggtac ctgtctctga ctttatctaa aagacaaaac agtgtacaaa
     8881 aagattttct tgggactgtg aaacgtccac ttgcaatggt tatcggactt actgcattag
     8941 tcgctattct tcccgatttt ggtaatgcgg cagttatctt tttgattatt ttggttctgc
     9001 ttttagccag cggagtcaat tatgtgtata ctttgattgt aggagtagga ggcttttgtc
     9061 taagtacttt tacgatctgg ctgatcaata tcacaaacgg aaagatctta cccggacgtt
     9121 tacagtatat ctataatcga tttgctattt accaaaatcc tttctcagac gaattaaata
     9181 aagggcatca actagtcaac ggctactatg ccatgttcaa cggaggacta tttggcaggg
     9241 gattaggtaa cagtatccag aaaaaaggat ttttacaaga agcacaaacc gattttattt
     9301 atgcaatcgt agtggaagaa ctgggagtga ttatggggat tttgatatta gcgttgctat
     9361 tctttatgat tgtgcgcatt gtccttgtag gtatccgttc aaaagatccg ttcaattcgc
     9421 ttttgtgcat tgggatcggc gcaatgtttt tgatccaagt atttgtcaat cttggaggga
     9481 ttactggcgt tattcctttg acagggatca cgttcccatt tttaagtcaa ggaggctcca
     9541 gtttgctgat gctttcgatt tgtgtcggct ttgtcctcaa catcagtgcg gatgaaaaac
     9601 gcaagagctt aggtttataa taaaaaaaga tgtaggagtg gttcgatgaa aaaagtttta
     9661 gttgctaaca ggggtgaaat cgctgtacgt gtatttcgtg cttgtacaga attaggaatt
     9721 aaaactgttg gaatctatgc agaagaagat gaatattccg tacaccgttt caaagcggat
     9781 gaagcatatt tagtaggaca aggaaaaaaa ccgattgatg cgtatctaga tattgaaggg
     9841 atcatttcta tcgcgaaaga atgcggagct gacgctattc atccgggtta cggtcttttg
     9901 tcggaaaact tgaattttgc gcaacggtgc gaagaagaag gcatcatttt tgttggaccc
     9961 aaactgcatc atttagatat ttttggagat aaaatcaaag caaaagctgc agctatcgaa
    10021 gcggggattg cttcgattcc aggcacagat ggaccaatcg cttctataga cgatgccttg
    10081 gagtttgcga aacaatacgg ttatccgatt atgatcaagg cagctctagg cggcggcgga
    10141 cgcggcatgc gtgtagctca cgatgaaaag agtgcaagag agggctacga acgtgcgaaa
    10201 agcgaagcaa aagcagcctt tggtagtgat gaagtgtatg ttgaaaaata catcgctaat
    10261 cctaagcata tcgaagtaca gattctcggg gatacgcatg gaaacgtcat ccatcttttt
    10321 gaaagagatt gttctgttca gcgccgtcac caaaaagtag tagaagtagc gccttgtgtc
    10381 tctatgaatg aacagcaacg tcaaaaaatc tgccaggcag ctgtccaatt gatgaaatat
    10441 gtcgggtatg tcaacgcagg tacagtagaa tttcttgttg aaggagatga tttttacttt
    10501 atcgaagtca accctcgcgt ccaagtggaa catacgatca cagaaatgat tacagatatt
    10561 gatatcgtaa caacgcaact gttgattgct caaggtttgg atctgcataa agaaatcgga
    10621 ttgcctcagc aagaaggaat taaattaaat ggttcagcca ttcaatgccg aatcactaca
    10681 gaagacccgt tgaataactt tttaccagac acagggaaaa tcgatacgta tcgttcacct
    10741 ggtggttttg gcgtacgtct ggatgtcgga aatgcttacg cgggctatgt agtgacaccg
    10801 tattttgatt cattgctagt aaaagtatgt acgcatggtg ctacctttga aacagccatt
    10861 cagaaaatgg aacgttgctt gaaagaattt agaatccgtg gagtgaaaac aaacattcca
    10921 tttatgctca atgtcatcac acatcctgaa ttccaatcag gaaatgcaaa aacaaccttc
    10981 attgatagta cagcaacatt atttgaattt cctcgactac gagaccgcgg aaacaaaacg
    11041 atgaaatata tcggtgaaat tactgtgaat ggttttccag gtatcgaaag tggcgaaaaa
    11101 ccattttatg aagaaccacg tatgcctaaa gatctaatca caagaactga ttacgtaacg
    11161 gctaagaatg tattagatgc gaagggtgcc gatgctttgg tcgaatggat caaaggacag
    11221 gaaaatttgt tgttgacgga tacgacattt agagacgccc atcaaagtct gctagcaact
    11281 cgtgttcgga caaaggattt caagcagatt gcacgtttga ctggagaagg tcttcctgaa
    11341 ctcttttcaa gtgagatgtg ggggggagca acatttgatg tggcttaccg ctttttgaat
    11401 gaagatcctt ggcaacggtt gagaaaaatt cgttctttaa tgcctaatac gttgctgcaa
    11461 atgcttttca gaggttcaaa tgccgttggg tattctaatt atcctgacaa tgtattggtg
    11521 gaatttgtca aagaagcagc agcgcaagga atcgatgtat ttcgaatctt tgatagtttg
    11581 aactggactc cacaaatgga aaaaagtatc caagctgtac gggatactgg taaaatcgca
    11641 gaggcagcta tttgctatac tggcgatatc aacgatccaa gtcgggcaaa atacaatgtt
    11701 cagtattata aagacatggc aaaggaacta gaacaactgg gtgcgcatat cattgcaatc
    11761 aaagatatgg ctgggctgct taaaccgcag gcagcttatc gtttgattag tgaattgaaa
    11821 gaaacgacag atctgccaat ccatctgcat actcatgata ccagcgggaa tggaatcatc
    11881 acttattctg ctgcttcaaa agcaggagta gacatcgttg acgtggcaat gagtgcaatg
    11941 agtgggaata ctagtcagcc tagcatgagc agcttgtatt atgcactggt caatggtcca
    12001 cggctgccag aaatcacgat tgaaaatgca cagaaattaa accattattg ggaagatgtg
    12061 cgcatgtatt acaaaccgtt tgaaaacggc ttgaatgctc ctgaaacaga agtatatatg
    12121 catgaaatgc caggaggaca gtattcgaat ctacagcaac aggcaaaagc tgtcggatta
    12181 ggtcatcgct gggatgaaat caaacaaatg tatcatactg tcaacttgat gtttggcgat
    12241 atcgttaaag taactccatc atctaaagta gttggagata tggcactatt tatggtccaa
    12301 aatgatctta cagaagaaga tatttatgaa aaaggcgaaa cactaagttt ccctgaatct
    12361 gttgtgactt tcttccaagg agaactaggg caacccgttg gcggatttcc taaaaaattg
    12421 caaaagatta ttcttaaagg cagacctgca ttgaatgaac gtccaggtct tttggctgaa
    12481 tcagtcgact tcaacgaagt aaaaaaagaa ttggcagaaa aaattggcta tgaaccaaaa
    12541 caagacgaag tattaagcta tttgatgtat ccgcaagtct ttttggacta tcaaaaagca
    12601 tataatcaat ttggcgatgt tacattactg gacacaccaa catttttcca aggtatacgt
    12661 ttgggtgaaa caatcaatgt acaaatcgaa cgcggaaaaa cgcttatcat tcgtttagat
    12721 gaaatcggag aacccgatat cgaagggaat cgcgtactgt tcttcaattt gaatggacaa
    12781 agacgtgaaa tcactatcaa agataattcg atcatcagta cggtccaaac ccgattgaaa
    12841 gctgaaccga caaaccgaga acaaattgga gcaacgatgt ctggttctgt tttggatgta
    12901 ttagtgaaaa aaggcgataa cgttaaaaaa ggtgatacgt tgatgattac tgaagcgatg
    12961 aaaatggaaa cggccatcga agcacgtttt gacggagaag tcgcacatgt atatgtgtct
    13021 tcaggagaca ctatttcgcc tggtgacctt ttgattgaag tgactgagaa ataataagcg
    13081 aaaggtgggg aaacatgaaa agactgggtt tgttttggct gattctgcta ttagttattg
    13141 tggcattcta catggaacca gtcttgtttc cgccaaaact tgaagtgaag gaaaactctg
    13201 atcaacaaat atcaaaccaa atgacaacgt ggaaatacca ggagcttaaa gcaactggtt
    13261 tttctactta tatcggaaaa ccgatcgatc agctggaaaa ggattttggc caagcctatg
    13321 atcgattaac tagcggattt ggttttgaaa caagatatta tgaaaataaa gctagtcatc
    13381 tcacatttga agcgaacatc caagacagca gagtcacaac tgttaaagta ctgcaaacag
    13441 ggcctgctga tatcgcgccg ttttatttag ggatgacgat gcaagatctt acgaaaatca
    13501 ctactatcta tactaatttc acttttgagt accatgatac agaagttgga atcgaactaa
    13561 tggaagagga tatgaattat cgtccgctaa ttgcttttga taacgacact tttgctattt
    13621 tattttttga tcaaacaaca aacggcctat tttcagttgt gtatttagat aaagatagtc
    13681 ttttgaaact attgccatat caagtgtttg gtgaaggcct tccacattat caagcagata
    13741 aatcggctga ttgggaatca atcaatcgcg ttaaagaacg aaaaagtacg actttattaa
    13801 atatgcttag aagagaagac gaacttccca tatacaatca aacacttgcc tttcaaaacc
    13861 acagtcagct gctactacat gattttttga caaggcctga ggaaatattg tcagaggaac
    13921 gtatggctga ttggcaaaaa tcgctaggca gtgctcaaac gacagtgaaa ttctcactga
    13981 cgaatgatga attggagaag ttaatcagta aacaaaaatt agaaaatact agtgggctat
    14041 ttattcatcc ggcgattgac gctacttttt cgtttttata ttggtacagc gatccttaca
    14101 accatgaccg tttcatggac ccgggaacgg attctgtagg cattgctttt tctaaagaaa
    14161 atatgttagt cttattgcaa gaagaaaacg gagaaagtag tgatagcagt gatcgttaac
    14221 gaagagctgt ttcaactgga ggatcaatgc ctccaagtcg ctgaaatgat aaaaaagagt
    14281 aaaacgatgg cttcttatct tgaacataaa cagtcaatgg aagaatctgc aaaagtttgc
    14341 cagttgaaag aagcgttctt gtctaagaaa gaagcatttg aaaatgtagc ggcatatggt
    14401 gagtatgcac ctgattatcg tgaaaaaaaa cgagctgttc gaaaagcaaa aagacagctt
    14461 gatatggatg agcatgttgc agctttccga tatagtgaaa cacagctgca aagtctgttg
    14521 gatcaaattg tccaagtact tgccgaagaa gtttctaatg aaatcaaagt agatgcaggt
    14581 agcccgtttt ttgaaacgaa aaaacacttt ggatgcggag gtaattgtca tgcaattaga
    14641 caatagtgaa tttgaaataa caaaacgacg cgggctgatc gtatgggtct acagcttaaa
    14701 acaattaaag aatctgaaaa agttcggctt gttgcattat gtctcaagaa gaatgaaata
    14761 tgtcgtgctt tacttaaatg aagagacatt ggaagaaaca gaagaacgaa tccgtaaatt
    14821 acattttgtt cgaaacgtag aacgttctta ccgaccggat atcgaaatga attttgccga
    14881 aaaaatagga aacaaaacag tattaaaaga cgaaggtttc gaaattgaag agctaaatac
    14941 agaaatccga ttagctgaac atctttaaaa atctcttatg agcagttttt aaataaaaaa
    15001 taacttggat aacgatcgat ttttgatcat tgtccaagta tttttttggt atactagtac
    15061 cagtaccatt tctaaggagt gagtagatgc ggataatatc aggaaattat ggcgggcgcc
    15121 gtttaaaaag tttagcaggg gcgaacacca gaccaactac agataaagta aaagaatcca
    15181 tattcaatat gattggacca tattttgatg gagagacagt attggatctg tttgcaggaa
    15241 gcggtggttt agctatcgaa gcagtatcta gaggctgcag tcatgcggta tgcgtagaca
    15301 aaaattacca agcgctaaaa atcatcaaag aaaacatcga aattacgaaa gaaccagaga
    15361 aatttaccac aataaaactt gatgcggaca aagcaatcga acggctagca gcggagaaac
    15421 aacaattcga ctacttgttt cttgatccgc catatgcaaa acaaaaaata atcgatcaaa
    15481 tccataaaat ggaagaactg ggactttttt ctaaaaccgc agttatcgta tgcgaaacgg
    15541 ataaaacagt cgaattgcca gaaactgtgg ctggattcca tcaaataaga aaacagattt
    15601 atggcataac ggccgtaact atctatagaa aagagggaaa tcaatgaaac gtgcattatt
    15661 cccaggaagt tttgatcctt ttacaaaagg tcacttagat acggtggaac gtgcggctaa
    15721 attattcgat gaggtagtaa ttggtgtttt tatcaatact tcaaagaaaa gtttgtttcc
    15781 cccagaagaa agaatgacat tgatcacaaa agctgtttct catcttccta atgtaaaagt
    15841 catgcatcaa gaaaatcaat tgacggtaga aacagcaaaa gagattggtg cagatgcgtt
    15901 gatcagaggc atacgaagta tcaaagactt tgaatatgaa cgagagattg ctcagatgaa
    15961 tcatcatcta tatgatgaat tggaaactgt cttcttatta gcaaaaccag aatatagtca
    16021 cgtgagttcc agtattttaa aagaagtact gcactttggc ggagatgtga gcagctactt
    16081 accgccagtg atcaacgaag ctttagctgg aaagcgtgaa tcaaatgaaa gctaaacaat
    16141 ggttgaaaac agtactgatt atcatatttg gaatgttgat cattggattt gtagtagttc
    16201 ccttgccgta ttatgtagaa tcaccgggag ccacgatcga tctgaaagaa ctaattacgg
    16261 tcaatgataa ggaagataaa ggttctgggt ctttctctct tacctctgtt ggtatcaggc
    16321 aagctacagg tttcttagct ttaaaagcta aaatgacccc ttttgaagaa ttgatcagtg
    16381 aagaagaatt gactggtggg gcgacaaatg aagaatataa tcaaatgcaa cagtattata
    16441 tggattcttc ccaaaatgca gcaatcgaac aagcgttaaa acttgcagac aagccttata
    16501 aaatggaatt caaaggcgta tatgtcatga gtgtagagaa aacatcgaat ttctttggca
    16561 agctttcagt tggagataca gtaacaaaag tagacgggaa aagctttcaa agtacagaag
    16621 catttatgga ttatgtaaaa agccaaaaag ttggacaaac aatcgaaatc agttatttgc
    16681 ataatggtga agaaaaaaca gcttctggtg atctgatcga gttaccaaca gataaaaagg
    16741 caggaatagg tatcacgctt actgaccata ccgagatcga atcagataca gatgttcgta
    16801 ttaattctgg ctctatcggt gggccatcag cgggattgat gttcacttta gaaatctatg
    16861 aacaagtcac tggtaaaaac ttgcgacatg gtaagcaaat tgcaggaact ggaacgatca
    16921 acagtgaagg agaagttggc cgaatcggag gaatcgataa aaaagtggca agtgcggata
    16981 aagctggcgt agagattttc tttgcaccag atgatacgat ttcagacgat gttaagaaag
    17041 aatatcctga aataaaaacc aactacgaag aagcaaaagc tgccgctaaa aaattgaatt
    17101 cctcaatgaa aatcgtacca gtaaaaacag tacaagaagc gcttgactat ctagagaaaa
    17161 tgaaatgaaa ctaaataatt aaagaggggt tgtgacacga gttctgtcac aacccctctt
    17221 tttcgtcaaa aatcttcacg ataaaaataa aaacaaaaga aaaaattgac gtaattagat
    17281 gttgaaggga cgattttgcc agagctcact gtttcttcaa ttttaaatga aaggagtaat
    17341 gaatgatttt tactggtcat tctttgaaaa aagaacaatg atagaaaaaa tcagcaagaa
    17401 aatactagct tcacccaaat tgatcatttg gatgtctatg atagttctta tcttttgtat
    17461 cgcaagtggt tttttattat caaatttgct attttataga gaaacagaag agactgctgc
    17521 aaaagaaata ctttcttcgt ttagttccag tggagaagat ccatcagctg aaggaaacga
    17581 tgtagaagag gatgctcgtc caaaggtcat gtacaccgat atcaaaggaa gtgtgaagga
    17641 gcctggtatc tattcctttt cttcagaaga acgggtctat gatgtactaa agcgtgcagg
    17701 tggattatta gaagaagcgg atagcgatcg aatcaacttt tctgcgaaga tagaagatca
    17761 gcaagtccta tatatccctg ctgtaggtga agagctgcca gaacatcttg atcagttggc
    17821 atcctcggaa ggaaaacagc ctacagcaga ttccgagcct cccaaaataa atatcaatac
    17881 agccactcca tcagaacttc agcagattcc tgggatcgga tcagtcaaag cgcaagaaat
    17941 cattcgattt agagaagaaa acggatcctt ccagaaagtg gaagacctgc aggagatttc
    18001 tggtatcggt gaaaagacag ttgaaaaact aaaaaacttc gttacaatta aatagaatga
    18061 ttcaaaatcg actggcacga gcaataaatg gacgctaatg gatactaaga ataatccaat
    18121 tctaagagct tggcaggacg aggaggtagt atttttggat aggaaatagc ttgattgttc
    18181 gcaaagaaac attaaaaaaa ccaatgctga atgtctatct ccaaaataaa atatctggga
    18241 ttcatattat gaatacggct gtcagcggca ataacagtca agctctacga gaacgctttg
    18301 ccaaagatgt acttagctat acagcagata aagtatttat tctcattggg acgaatgatc
    18361 tagcagagca taaacaactt tctaaagaaa cgtaccaaaa aatctgcagt ggatgatagt
    18421 tcagctgaaa aaagactata gttctgatca tgctttcttt atcacgccac cagcagtcga
    18481 tgagacaaaa caaaaatatc ggaataacaa gttgatcaaa gaatatatct ctgttctcac
    18541 agaagtagca aaacgccatg attgtgaagt atcgattttt atacggaatt tcttgaacaa
    18601 atggattcga agaattttta taatgggcta atggatgacg gacttcattt cggcagtgaa
    18661 gggtaggatc ttttgtcaga caggatgatt cgttatattt aaagaatatt ttgtttaagc
    18721 aatgagtact ttttaatcaa cttgaaaaaa cggaggaata taaaacatgt tagaaaaatc
    18781 ttcaaaagca tgcgatacga ataaagaaaa agttactgat aagtcacata atgaacgcat
    18841 tccttgggac cagtacttta tggctcaggc agtactgtta tctttacgta gtacgtgtac
    18901 acgtttagaa gtaggagcga cactcgttcg agaaaaaagg atcattgctg gcggctataa
    18961 tggagcagtc agtggagatg tccactgcat agatgaaggg tgttacgtcg tggatggaca
    19021 ctgcttgcga acgatccatg cagagatgaa tgcactccta cagtgtgcaa aacttggtat
    19081 cccgacggaa ggttcagaaa tctatgtcac acattttcca tgtttggcct gtacaaaggc
    19141 tttgttgcaa gctggtgtga aagggatcaa ttatctccat gactatcgaa atgatcctta
    19201 tgcccaagcg ttgatcgaac aattaggtgt atctgtacac caagttgctt tagactcaca
    19261 gcatttttca aaacttcaaa atgaattaac aggaaaacat gtctagcgtt ttagaaaggc
    19321 atgttcgaaa tcggttgatt tttccggcaa ttacgtcgat gattatctgt ttgttgtatt
    19381 acactgacaa ttggggttat cgtttgcttc ttgccggaat ttttttatgg ttttcgctaa
    19441 aagaaggacg ttttatcgcg tacttgtgta ttttgtgtag cataacggta tccatttctt
    19501 ataggctaca agagtattca tttttagagg aaaaaacaac atctgcgcaa attactgtat
    19561 ttacagatac gattcgtgca aatggtaatt ttttgacaat ggaaggaagg ttatcagaga
    19621 ataaacaaaa gctccagctt tcttatcaag taaacacaga agcagaattg aaaacatggc
    19681 ttaacttccg aggaaaggga atagaattga ctgctgaagg cgagttcatc tctccagcaa
    19741 aaaagcggaa tctttataat tttgaccaag aagcttactt caggaaccat agaatttctg
    19801 gacggttcca aattcaaaag attgaacaga tcaccatgca aaatcactgg cgaaactggc
    19861 ttcagagaaa aagaggatct tttatctcct ttgtccaatc tgaatttccg caaaaaacaa
    19921 gtgtatatat taattcttta ttatggggct ataaagatgc aggattcaga gaaccagaag
    19981 aaatttttag ggagagtggt ttgctgcatc tgttcagtct atcgggtcta cacatccaat
    20041 tttatttagg gtggctgtat tatttatttc gacgtatcgg atggccacta cacgtcagta
    20101 ttattccgtt gagtctacta actatctgtt atgtttctat tgcaggaagt tctatttctg
    20161 ttttgcgtgc tagtttgctg tttttattgc gattgctagt caaattgctg aataagcatt
    20221 attccaccat ggacttattt gcagttgtct tttggcttct tttactattt gatcctcgat
    20281 ttctttttca tgcgggtgga cagcttagtt ttttcatgag ttttttgttt atcctgattt
    20341 cttttgatgg agattggttg aaaaaaacgg cctctcacgt cctgtttact atgatcacga
    20401 tgccgttgat tgtatggcat ttttatgagt ggcctatttt aggtagtctt tttacattac
    20461 tgattgcacc ggtattcaag tttctttttc ttcctggtgt gttatttctc acactcttca
    20521 atcgctggct gccggaaact ttacttttgc tgatagaaga gggattaatc ttatttgagc
    20581 gaataatcga tttttcttca gggtcgtctc tcattatagg acgtttgccc cttgtgctat
    20641 ctgggatgta tattttcgga ttactgattt gtatggatag gttgaaagaa caacctgtga
    20701 aacacttgtt ttatgttggt cttttttctt ttattttttt gactttgcca tttttacgct
    20761 tttcttcaac gatcgctttt atcgatgtcg gtcaaggaga cagtatcttt ttgcaaagtc
    20821 cttttcgaaa agaaacgatt ttgatcgata ctggaggtca gttacacttt gaaagagaaa
    20881 agtgggcgca aggtatgata cgtcctcctg ctgaaagaaa tatcgttcca tatctaaaag
    20941 gtcaggggat aagtgtaatc gataaactca tcttgacaca cgacgatacg gatcatgtgg
    21001 gagaattacc cacgttatct cagcatttta ctatcaaaaa aatttatatc ggttggggcg
    21061 ctggacgaaa tgagccatta caaaggcatt tatctgaagc tcaaaaaaat ggtactgaga
    21121 tcattgaaat caaacatggg gacaggatca gcggttatta tgatctttat gtattgactc
    21181 cttttgaaaa gggagaggga agaaatgaag attcgattgg tctatggatg gaatataaca
    21241 ataggcgctt tttattttta ggagatttga atcaagcaat ggaaaaacaa ttgcttttga
    21301 tttatcctaa tctgaaagcc gatgtagtca aattaggtca tcacggtagc cgtacgtcaa
    21361 gtaacacaga ttttctttcc catattgaag caaaacatgg gattatatcc tgcggcgtaa
    21421 ataatcgtta tggtcacccg cacagcgaag tattggagac actagaagaa aatcagataa
    21481 aaacatggcg aacggatcaa caaggaatga tcacctatcg ctggcatcca gtttttcatc
    21541 ctcatgggct agtggaaaca atgatagact agtaattctc atctgctcat ggtaggataa
    21601 tttttgaaag tggtgagtaa tttgagtata caagcagagt tacaaaaaat acgtaaagaa
    21661 aaacttgcat cttgttactt gattttagga acagaaaagt ttctccaaga tcaagttcgg
    21721 acagaaattg tcaaaaaaat ccaattagag ggcgaagatg acttaaattt tttaagtttt
    21781 gacatggaaa atgcaagttt agatgaggta gtagctgaag cagagacgtt gccgtttttc
    21841 ggagatcaac ggttagtatt cgtagagaat ccttattttt taacaggtga aaaagtaaac
    21901 aatggaatcg aacaaaatac tgatttattg acggcttatt tgaaagaacc attagaatcg
    21961 actgtattag tattctttgc gccatatgaa aagttggatg aacggaaaaa agtaacgaaa
    22021 caattgaaaa aaacagcaat tatcatcaat gtccaacagt tgaatgaaaa agaagtacgt
    22081 caatatctga tgaatacctt agagaattcc tcaatcaaaa tggaacgaag tgcaattgat
    22141 ttattcttga ggttgaccga cttagattta tccaaaatga tgagagagtt acagaaattg
    22201 gtcctttatg gacaaaatca acagcaaatc acggtaagag aagtagaaga attagttcct
    22261 aaaacgttag aacataatat ttttgacatg acccaatata ttttaaaagg gaagacggaa
    22321 caagctttgc gtttatacga agatttagtt atgcaagggg aagaaacaat caaaattaat
    22381 gcgattttgc tttctcaatt acgtttattt ttacagacaa aatttcttgt aaagattggt
    22441 tatcagcagg caaatattgc tgaaacattg aaaatccatc catatcgtgt aaaacttgcc
    22501 atgcaggaag taaaaaaatt cgatgaacat ttgctggtac agttgtttga tcaattagtt
    22561 gagatggatt atcaaatcaa aacgggacaa atcgaaaaag aattaagttt tcaactattc
    22621 gttttgcgca cagggcagtt gttaagaaat cgataagaag aaagacgagg gcaaagcatg
    22681 cgggaaggtc gtttgttttt gtcctttttt tgacaaataa aaaaatcggc cgaagccgat
    22741 tcttttattt agcgattttt ttgcttaaac gagatttgtc gcggttagct ttgtttttgt
    22801 ggattagacc ttttgattca gccatatcaa tagctttaac agcttcttta tataacgcat
    22861 ctacgttgtc agcacctgaa gctacagcat cttcaaattt tttgattgca gtacgcatag
    22921 cgcttgtttg agatgaattt ttcacattag cgttttcgct tgtacgaaca cgtttgattg
    22981 cagattcaat gtttggcatt agtttcacct ccgataactt aagttcttac gcgtgttacc
    23041 gcataattca acattcatta ttatacctaa aggcagcgtg ctttgcaata tgaacatgac
    23101 aagttttttt ccttaacagt cttttattag gatttttttt cagtaaaaac ggatagtaca
    23161 agctgaaaaa aatcaaaaag acgctattgt gggaggcaat agcgtcaaac caaactagat
    23221 ttttatttat ctatttaaac aaagtttgaa tgggaatgtt tggtactaag ttattatata
    23281 acaaagagaa ccgtttgcaa agtttttttt gaaaagggat acgattccct gttgttcttt
    23341 gtttttctat taagaaactg cagttatttt ataaccagta tcctttgatc agtaaaggca
    23401 ttctggtgta ccgattattt taatgtattc atcgatattt tttatcaaca ttttttttat
    23461 gaccaactgg ttccgacggt tccatttgcc acttacttcc agcacatatt tatttagggg
    23521 caaacgtaag atatattttg ccaaatagcg atctttaagc aggccattga tcacacggtc
    23581 ctcaagctgc aagttgatcc cagtcagcat cattggctgt tcttgtaaaa cgtacgtatc
    23641 aattaaaaga ccttcaaaag tttccacaag cgtcttcctt tcttttcaaa gtaacctgaa
    23701 aacaggcact aattcttcca ttttgatatt cgttgaagtg gatgcgatca ttctttcttt
    23761 tgtccactgt aatctagtat aacaaaaaag agcagaagag ccaaaaagaa aaaagagcat
    23821 cgaattctat aggaagtctc attggcacgg cctaaattat tacaaaacat tgattaaaaa
    23881 aagcccctgc atcgcaggag catcccctat atcgttttaa taggtcaatc aaaaagcagt
    23941 atcaaacaca ttttgtatca aatcaggaaa taatagataa gctaagccca gaatcaaaag
    24001 taccgctaga agaaaccagc cgattgttcc tatgaaatac tttaattttt cgaacattgt
    24061 atcacctcgt tgtcagtata tcacggatca gtaaattggg ggtgttaaga atctcctaaa
    24121 atagacaaaa tttgttctat tttcctaaag caaatacttg taagatacag taagtgatac
    24181 cagaagcaat gaccggtccg gcggcgattc ctcttaagaa gacaacacct aaaatcgtgc
    24241 cgaaaacaag tgcaacagtg atttgtggat cagaagcaat caatcctaca cccttggaag
    24301 ataagacagc cactagccca ccgcaaaaaa cagctaccca gccaataggg gatttaaagg
    24361 cttctaatag atcacgtaga ccgatttctc ctgttgcgat agggattaga atagccgctg
    24421 tgatgatcgt caccccaata ttgattcctt tgccttgaag ccaagggaaa aaggaacggg
    24481 aggctggtat gagcttcata atcaaaacaa aagctgccgc tatcatcaga ctttgatttt
    24541 tagctaaaat tgctacaagt aaaataattc ctaaaaaaag ccaactttcc atgaaatata
    24601 ttcctcactt tcttcgaaac aatcataaca tgtttttaga aagttacaaa agtaggaatt
    24661 catccttcaa gacctattca taagctgttt ttttcataaa ataaacaaaa tcataaaaaa
    24721 acactttgct tatttgacag aagacagccg cgctttgtat agtggacaag acttacattt
    24781 ttttgaagaa tcagaaagat caggtaaagg tcttagtaaa cgcaagccat tcagaataac
    24841 caatattgtg cttccttcgt gtcctacaac tccaagaggt agatttaaaa attgcaggaa
    24901 gttagaagca atcaacaaga gaataacaag aatcgaaaaa ataatatttt gtttgatgat
    24961 ccgccgcatt tttaaagata gccgatgact gtagacaaat ttatttaagt cgcttttcat
    25021 taagacgatg tctgcgatat ccatagcggc atctgtccct tgccccatag cgacacctaa
    25081 agaagcggct gctaaagcag gcgcatcatt gactccatca ccaaccatcg catttacttg
    25141 gtaaagttca ttctcttttt tgactagttg tgttttttct tccggagtac agcttgcata
    25201 gtaatgttca atccctactt gttcagcaat ggcctttgct gtgccagaat ggtcgccggt
    25261 tatcatactt gtatggatgt tttgggattt aaagtaggaa attacttgtt gggtatttgc
    25321 ttttggaata tctagcagac ctaaaacagc aattaactgc tgatctttag aaagataaat
    25381 cacggttttg ccttgatttt ccaaacgttc gatcatttcc gcaatctctt tgctgattat
    25441 catcgtctca ggatcatatg cgtgcttgcc aactttccat tgcgcaccta aataggtagt
    25501 ttgtaatcca aaaccagtaa tttcttctat tggtaagtat tggatttctt caggtattgt
    25561 gcaatcgaaa tattgcaaaa tcgcatgagc aagtggatgc gtcgtttttt gttccatagc
    25621 aacaagaagt tgttgtgcca aatccttttc atcaaagaaa aagctgtcag ttacaactgg
    25681 ttttccttta gtgagcgttc ctgttttatc aaaggcaatc gcttttaatt cagaaagctt
    25741 ttctaaatgg ataccgcctt tgattaaaat cccatttttt gcagaatttg aaagagcagc
    25801 tagagaagct ggtgtagcag atgcgacaag cgcacaagga gaagccacaa ctaataatac
    25861 cattcctcga taaaagcttt catcccaact ccaacctagg aaaaagtggg ggagaaggat
    25921 cattagagga acagcaagca aaatcaattt tacataatta ttttcgattc gttcgataaa
    25981 tgaagctgtt tgagttggcg tattctgcgc ttcttctact aattggataa tcttagcaaa
    26041 gacagtttcg gaactcgttt ttgttactcg aatcgtgatg ggatttcctt gattcagcgt
    26101 tcctgcatac atctcatcgc ctaaatattt ttctacaggc acagattcac cgcttaatgc
    26161 agactcatcg atcgttgcct gtgtgctttc taaaaagcca tctatcggaa cagctgctcc
    26221 tttagcgaca aataccaagt tatccacctt tagttgagaa acatctactt cttgcatttg
    26281 tccattttct tttaataatt gggctttttg tggttgaaga ttcatcaaag cagtaatttc
    26341 tttttgactt ttattagttg tgtattcctc taatgcaccg cttaaacaaa agatgaatgt
    26401 caacattgct ccttcaaagt aattaccgat caaacaggca ccaatagcag ctaaagccat
    26461 caataaatcc acattcagtg tccgatcatt ccacaattct ttcaagcctt ccgatgtttg
    26521 tttatatcca ccgatgataa tggcactgat ataaaaaagt ggggtgatgg taagagagaa
    26581 tcggtcgaag ataaaaccga agatcataaa taaaaggcag ccgattgttg ctgcaaaagc
    26641 ttttttctga ttagtcatcg ttattagacc tccttgtcaa aacaaggata gcataataaa
    26701 aatgtaattg ataataataa cagctaaatg agaacgataa tggttatcat ttggtgatta
    26761 agcttgatgt tgtttttatt atttataatg attattatta aagaaaataa aaaaccagaa
    26821 catttctcaa ataagagaag tgttctggtt ttttctacat tgcaataaac caataaccaa
    26881 tcaaaatgat accaaggata atacgatacc agccaaaagc ggtaaagtcg tttttcttca
    26941 aatagcttag taagaatttg atagctaaga cggaaaccac aaaagatacg aatgttccta
    27001 caagaagaac aacagtttct tccattttga atgaattccc ttcagctaaa tatttgacga
    27061 tcttcaagcc gcttgcgcca aacatgacag gaatccctaa gaaaaatgaa aactctgtag
    27121 cgacaaaacg cgaagcacca atcaagatag atcctaggat cgttgcgcca gaacgggatg
    27181 ttccgggaac aagtgccaag acttggaata acccaacaag aagagctgct tggtacgtaa
    27241 agtcattcag agaagtccaa cgaggtgttt tgtttttgtt gcgtttttcg acaataataa
    27301 aggcaatacc gtaaacgatc aaaacaatgg caactggtaa gaacttgtgg aaatttgctt
    27361 ctaaccaatc atccaaaggc aaaccaatga tgatggctgg tatgcaagca acgatcactt
    27421 taaaccaaag tgtccacgta tctttttttt ctaccgttga tttacttgga gaaaatgggt
    27481 ttaacttgtg aaaataaaga acgacgacag ccaagatcgc ccctaattgg ataacgacat
    27541 tgaacatcga cataaattgt gaactggcat ccagtttgat gaattcatct gctaggatca
    27601 aatgaccagt actactgatg ggcagccatt ccgttattcc ttcaataata ccgagaatca
    27661 ctgctttgat aatatttgca aaaaacataa attccttcct tcccaattaa gatacatctt
    27721 atagtatacc gttatttttt gagaaaccca atctgttttt taatattaag aaaaacttga
    27781 gaaataaagc agataagtac acgaagagaa aaaagaagac aaagccctcg ttcagacttt
    27841 gccttttatg attctctggt aaaaattaaa atatccccat tatagaaacg agtcgcgact
    27901 atgtgttttc ccgttatcga tataagacgt atcattgatg ccgtggatag aaaatcgacc
    27961 gtttgcataa gtgacctttg ttacgctgcc atttaaaagc ccagcacgaa caggctgttt
    28021 aggatcgatc agattaagca aaaaggcgat cgtcaaacca tgagatacga ctaaaacatt
    28081 tccaccacca tttttttcgc agtgatgggc gatatcttca aatcctgtcc atacacggtc
    28141 tcgcaatgtt tcataagttt ccgcccaccc agcggtatct aagttgtata cagcattagc
    28201 aatttgttca aaagaaactt ctgtggtaaa catttcatca tatgttttaa aattcaatac
    28261 acgagggatc acaccccaca tttccatgtc atatccacct tcaagagacc cgaaacacca
    28321 ttctctaatc cttttttcaa taaaataagg aatttctttt cccttagaat gttctcctag
    28381 aataatacgg gcagtttcga ttgcacgacc actgtcacta gaataagcaa atgaaaagtc
    28441 gacatttttt aacccgcgac ctaaataatg aatgccttct tgtccttgct ttgtgagggg
    28501 tgtatcacac cagccttgta ctcgttcaat tgtattgaac atcgtttttc cgtgtcgtac
    28561 gatataaagt gtagtttctg tcattttatt ctcctcctaa gtcgttttaa cgattgaaaa
    28621 aaggatttgt ccttttttcc tgttcaatcg tcgttgcatc gccatgtcct ggatagactg
    28681 caaattcatc aggtaataca aacagctggg tccgaatact atgaagtaat tgttctaaat
    28741 tccctgtata cagatcggtt ctaccgatac ttcctctaaa cagggcgtcg ccagaaacga
    28801 caaaatcatc aaaaataaag ctgacgcttc ctatagaatg ccctggggta gggacgacgc
    28861 gaaaagacat gtttcctaaa gtataagttt tcatttcaaa ttcatattct gcaggcgaga
    28921 caataacatc agcaatatca tcatgtctac cgagtccaga aagattcaaa atcggatcac
    28981 ctagccattt ttgctctagt gggctgacat aaactgggat ttgataatac gcgcgtaaag
    29041 gttccactgc accgatatga tcgtagtgag tatgggtaag caaaatcgct accggctgtt
    29101 ggtttgtttt tttgatttct tgtttgattc gttccgcatc ttctccaggg tcaatgatca
    29161 aaagtgcttc ttcgttgtag accaaataac agttttcttc aatcattcct gtttttaatc
    29221 tttcgatatg catgtgcatt cctccttgat agccaaaact tctttcatcc attagtataa
    29281 cgcattcatt gctaggaaac aaaaacaggt acttatttct ctttacttat ctgaattatc
    29341 agactatatg aaaagtattt ggatattcta aagagaagga aagtaagttt tcatagcatt
    29401 ttaatatgtc cttgttacat tagattcatc caaaaatcca aattctatat cctatatccc
    29461 tgcctaatca gcagggtgtt tttttatgtt tggaaagaga gctctttttg ctaaactagg
    29521 ttttttcagg taatcttaga gagaaagagg tggtggaaat gatcaaacag tcaaaaatat
    29581 ctgtgcggca cttagtagaa tttattttgc gacgtggaag tatcgacaat cgtaaaaaaa
    29641 gtaaccatac tgcattagaa ggagcgagaa tccaccgcaa gctccaaaaa gatgcgggag
    29701 aaaactatga aaaagaagtc tttttaaaaa caacagttca attagatgaa tattacctga
    29761 tcgttgaagg ccgtgcagac ggtattttca aaagagacgg tatttattat atagatgaaa
    29821 tcaaaacctc cgaaccacga tttgaagatt tagaaccaga acaagtggaa cttttctttc
    29881 atcaagcaag ggtgtatgcc tatatctata gtcaagaaca tgatttacaa gaaataaatc
    29941 tgcaattgac ttacttccag acggcagaag aagtgatcac gagaaaggtt gaacatcaga
    30001 caagagagca gttagaaact ttttttaaaa agctgactga agattataaa gaatggcttg
    30061 tttttcaaga aaactggcgc actgtacgca atgcctcttt gatggctttg aaattccccc
    30121 atgatgagta taggaaaggt cagcgtgaac tagcggtagc tgcttataaa acgatccgta
    30181 cgaaacagaa attgtttgta gaagcaccta ccggaacagg aaaaacaatc tctacgttat
    30241 tccccgcttt gaaagctgta ggggaagaag agggagaaaa gatcttttat ctaacggcta
    30301 aaacaataac tagacaagta gctgaagatg ctatgacagc attaaaagat acaggagctg
    30361 aagtaaaaag tgtcactttg acggcgaaag acaagatctg ctttttagat gagacgacct
    30421 gtaatccaga tcagtgccca tatgccaatg gttattacaa tcggattaat gaaggtttat
    30481 gggatctttt gaatcatgag aatcagatca ctcgtgaagt catcgaaact tatgcaagaa
    30541 agcatacact ttgtcctttc gaactatcat tagatgtcag tatctggtgt gacgtaatca
    30601 ttggggatta caattattta tttgatccaa ctgtttattt aagacgtttt tttgaagatg
    30661 aaaaaaacga ggactatctg tttttgattg acgaagcaca taatttggtg aatcgttccc
    30721 gagagatgta ttcggcagaa ctatcttatg aaaaaacgaa acgaagtaag gaagctatac
    30781 caaaggaatt caaaaaactt catcgccgtt tcaacaaact attaaaagaa tttgattcga
    30841 tccgagaaat agcaaaagaa gatcattggg attatcatca tcaaaaagca ccggctgaat
    30901 ctttagtaaa ggcaggttat caattaagcg aaaaaattaa agaatggctg gcagaatttc
    30961 ctgagcaccc atcacaagaa caattgcttc cttattattt tgatttgctt cattttttga
    31021 aggtcagtga attttatgat gatcactacg aaacaacagt cgaaaaaacg tatcgcgatc
    31081 tgatagtaaa agagttttgt attgatccaa gcttgtttct tgagcagtcg ttggataaag
    31141 gaaaaagcag tattcttttt tctgctagtt tttcaccact ctcttattat caggaaacac
    31201 tggggggaca aaaaagtctg gcttacaaac tgccgagtcc tttcccagaa ggaaaccagc
    31261 aagttttcat cgcaaattac ctagagacga cttatcgaaa aagggaacac agtctggcaa
    31321 aattagtaga gacgattcat gcttttgctg atggaaaggt cgggaattat ttcgttttct
    31381 ttccttctta tcaatattta gatcttgcgg tggaagcatt cagacagcaa tatcccgaca
    31441 gcaatgtgct aatccaagaa acggacatga atgaggaaga acgcgaacga tttttaacaa
    31501 aatttcaaac aaatcccgct gaaacattga ttggattttg cgtacttggc gggatttttt
    31561 cagaaggaat cgatttgaga ggggaccgat tgatcggcag tatgatcgta ggtgtaggtt
    31621 tgccgcagat gaatcatgag caggaactga tcaaatcata ttatgatgag aaggaacacc
    31681 ttggatttgc ttacgcttat cagcttcctg gaatgaacaa agtcttgcaa gctggtggtc
    31741 gagtgattcg tggcatggcg gatcaaggaa tcgttgtatt ggcagatcaa cgattttcta
    31801 gtttttctta tcgacgttta ttcccacaac attggcaaac agcaagagaa gtacgaagtg
    31861 ttggggaatt ggaagaagga atacagcgtt tttggttatc aaaagaagca gtaaatcaaa
    31921 aaaacgagga atgacagacg tcagcctcgt tttttgatta acgatagtta gtgaattgca
    31981 actcgattgg taagtcaagt ttacgtaata aagcaatcac agcttgtaga tcatcacggt
    32041 tcttacctgt cactctaatc tgatcttctt ggatttgtgc ttttactttc agtttttcat
    32101 ttttgatagc tgtagtgatt ttcttcgcgt tttcacgatc gattccgttg accaaatcgg
    32161 cagtttgtcg agctttgcca cctagagcgt gttctgattc ggaaaaatgg atatttttga
    32221 ttggcacatt tcttttgatc agcttaccaa ataatacatc tttgatctgt tcgattttga
    32281 aatcatcatc gctcaataca actagattgc tgttctctaa tttgatttct actgtagaat
    32341 ccttgaagtc aaagcgattg gacaattctt ttgttgtttg ctgaatcgca ttttttactt
    32401 cttctgtatt gacttctgat acaatgtcga agctagcatc ttttgccata ggaaccctcc
    32461 tgatatacat ataaatattt accatacatc tatcttatca taggattagg gcagattctt
    32521 acctgtttgc taaaattctt ctcatttgag ttcgaagtat tttattttaa tagataaact
    32581 gttattctta catttggaat accaaagtag gggagaggtg cttgtgagta aaattatgac
    32641 tgcgtatcat aaaaatgaaa gattaaagaa aatagtggtt attttgataa ccggattgac
    32701 cgctgcggtc gctttaaatt attttttgat tccagccaat gtcttttctg cagggatgaa
    32761 tgggatcgct caaatcattt cctcgctttt atatgaatgg tttcatatca agatagacac
    32821 aggaacattt atttttcttt tgaatatccc tgtgtttgta ttagggtttc tcaaagtagg
    32881 aaaacgagca acgatcctta gttttgtgaa tgttgtatgt gtatcggtga tgacgatgct
    32941 gcttccagtc ggacagatca ctgataatat tttgatgaat gccctagtag gcggtgtttt
    33001 attaggtctt ggcgtaggat tatctttaaa aatgggcttt acaactggtg ggatggatat
    33061 catctctctt gtactttcac aaacaactgg aaaaacagtc ggaaactaca tgctgattct
    33121 aaatggtatc attgtagtca tcgcaggctt cttctttaac tgggaaagtg ccttgtatac
    33181 gattatttcc atttatgcaa tgactcaagt aattgatgcc atccacacga gtcatcaaaa
    33241 agtaacagca atgatcgtta ccgtcaagcc agaagaggta acagaagaac tagcaaaacg
    33301 gatggtacgt ggaatgacat tactgccgtc tgtcggtggc tattcaaaaa aacaagggaa
    33361 catgatcatg atggtcatca cccgctacga aatgtatgat cttgatcaga tcgttcatga
    33421 aatcgacgac gatgcattta tcaatatttt accaactcat tcagtatttg gccggtttgc
    33481 aaatgaaaac gaacaaaaaa tgtatcgaac aactggcgta ttgccagaaa taaaaaatcg
    33541 ttcacaaaaa aaatgaggaa tcaggtttat tttagaataa atttaatcta ttacatctaa
    33601 taagaacatt tttataaatt taaacgagaa tcttacttct aaattctcat ttacaagcag
    33661 ctaaaaaaag agtatgataa ataaaaatcg tgttaaggag tgtcgtacga tgagcgaagc
    33721 aaaccaagaa cggtctggac aagaaataga actaatcaaa gaacgtattc ttgctgcctt
    33781 ggaaatggtg attgatcctg aattaggaat cgacatcgtc aatttaggct tgatttatga
    33841 tatagaattc aatcctgaaa atggagaaac agtcattaag atgactctaa caactatggg
    33901 ctgtccatta gcagatattt taacagaatc tatccatgac gcattaaaag aagtgccaga
    33961 agtaacgaaa gcagaagtca aactagtctg gtatccagca tggacgacag ataagatgag
    34021 ccgttatgca cggattgcgt tggggatacg atagaaatct tggctgacta gctatgagaa
    34081 gcaaatagga aaaacaaaaa agccttttat cctttctaga agaaaagaga taaaaggttt
    34141 ctttgtttat aaaattttgt ctgctatatt ataagttaat taaataaatg tgttctattg
    34201 ataaaggaca ttcaaatccc tttccttttg gaatccttct tttttacatc agtttgattt
    34261 tcgtatagta ttctttctca tcttcacgat aaatcgcagc cccatttttt tgttgtgctt
    34321 taagactgcc aagatttttt ttatttacag acaaaagtgc ctcatcaatg ccgatttttt
    34381 ttgcctcttg tagtactaat gctaatcctt gtgtggcata tcctttttta cgataattag
    34441 gggagatgcc gtaaccaata tggccagcgc cgtttcttaa tgtttcgttc agtttatggc
    34501 gcaaattaaa aattcctaca tactcatgtt catcactttc taaaataaag acggttgcgg
    34561 gaacgtaact ctcaggaaga tcgattccta aagacgtttt ttcgcatttt tttacataat
    34621 ctaaaaattc agcaaatgta tagccataag cattgttgat aaatccactc tcatttggtc
    34681 caaagctagt ttgtagctga taagctttct ttaaatctgc ttcccatagt ttgatcagtt
    34741 tcatcgtatt cacctcttta agtaacctta ttcatttgtt ttctactata gcactattgt
    34801 tgtaaatagc catgcctatt tttatttatt gtgtcatatc gtattaagaa tcatcgaaca
    34861 atacaaatat gaattacaat aaaaaaatta tttgaagttc gttcattcgt tacttatgat
    34921 ctctagaaga aagaaaacgt gaattacttc agcgtctaga attccagaag gatagtaatc
    34981 aacagaagaa ataatcaata tccaaatgaa agaagatagc tgaatcgaga aaaagaggaa
    35041 aaaagaaatg aagaaaaaaa taaaatagtt actaatccca gagtcgttcg tttaacattg
    35101 aaatcgatca tatggataaa acagattttt tcaccaaccc tcaatagatg atggagttgc
    35161 tcggatgaat tatttgtgta gatggcataa gggagggcgt acagaaatga aaaagaacaa
    35221 aaatatgttc ttgacaaaaa acacatgtaa tcctaaacta aaagatgtga tgcggctatg
    35281 gcggaattgg cagacgcgct agcttcaggc gctagtgagg gtgacctcgt ggaagttcga
    35341 gtcttcttag ccgcataatt tgttttttta taaagagaag gtacacctgg agcgatgaga
    35401 aagaaaataa catattatct aaaagaatat aggaaaaatt ttaaacaacg gaaccagatt
    35461 caaataaatc aaaaaaaatt tgtgtgaagg tgggacagtt taaaacctaa tagattgatt
    35521 caaatagtag atttatagat tctgatacaa gaaatactgg caaacgatag ttaaggaata
    35581 aagactaaac ttaaactcaa aaagaggtca tgcgaaagaa taaatcgcat gacctcttac
    35641 tatattttga atgtgtttaa acgttcaaat aatgaatctt agtaccaacc gtttgcttcc
    35701 cagaatgctt tcgccgcttc ccaagaacca taacgtgaag taacatattg ttctgctact
    35761 ctttcttggt ttgcagcaga gtagtcacca tttaagtaag aagaatctaa ttggtaacgg
    35821 ccgatgtaac gtccgttcgt tgctgtgtaa gaaccgcttg attctttttg tgcgatccat
    35881 tcttttgcag agcttgtact tgctggagta gcagcagttt ctgttacagc aggagcaggt
    35941 tgtgtttcag caacaggcgc tgcttgtgtt tccgtttgaa ccgtttcttg tacaacaggt
    36001 tgttcagctt gaacaggttc agcttggact ggtgcttctt gaacggctgc ttgaggttca
    36061 gcagctgctt gtgcagagcc ttctgttggg attgttaatt gttgtcctga gtagatcagg
    36121 ttaatatcag aaattgaatt tgattctgca atggcattga tcaaggagtt atcaccaacg
    36181 tatttttgag aaatcgttga tagagtatca cctgattgaa cggtataagc ttcgtccgca
    36241 tgagcagtcg ttcccatgaa gaatgcagcg ccggcagcca aagttgttcc aaaaagtaaa
    36301 gttttaagtg atgtcatgaa aaatctcctt tattcgttaa aaagttttat ttgttgtgtt
    36361 caacgaggaa tactttaaca cgtgaaaata tttcataggt aaaagaagca tgacaattta
    36421 tgacaaatcc acgttttttg taacagaatg atgttcgctc gatgtgaaaa atgatgagga
    36481 atttcacata atgcagaaat aatgggatta gaacaggtgt tctgatgaga aaagaaatgt
    36541 ataaataact tgaaagaaat tgcttttgtt catcatttta tttacatatt gcgtatattt
    36601 tttgtatttt tgcttgagat gttacaataa aagaaaaagg aggcggttcc aatgagtaaa
    36661 agataccaga acatcatggt agcagttgac ggatcaagac aatcgatcaa agcgttcgct
    36721 gaagcccttg acttagcaaa ggacaatgaa gcccacttat ttatcgtgtc aatcatcaac
    36781 aaagttgagc tgacccatag tgcctatgcc ttttcaaaaa tctatgcaga tgaaaaacaa
    36841 agaacagaag tagccatgct gaaaaaaatc aatgatgcca aagagtacgg cattgctgag
    36901 atccacgcaa tagttgaaac tggagatcca agaaatttga ttgccaatgt catccctgga
    36961 caagaaaata ttgatttgat cgttatggga gcgacaggaa aaggtgctat acaacaagca
    37021 ttagttggat cgaccgcttc ttatgtcgta tcacatgccc cttgcagtgt gttggtcgtg
    37081 aagtaatgag ataagggagg aatagaaaat ggttcgtcct caagaagtcc gtgcgccaaa
    37141 agaaaaaata gaaattttag caattattga agacggcaca caaacaaaga agggatactc
    37201 gatcgcttta gtaaagtgga aaggaaaaaa aggtgttgct ctgagatggg atggagataa
    37261 ccaacaagat aaaggattcc ctgtcacagc taacggttat catccagcgt ggtttgttct
    37321 gcctgataaa tttatggaat tatacagcta tgattatgca agagccgcag catcaatcaa
    37381 agcattagat aaattaacag aagagcagaa tgaaatggag gaaaaataaa aaagacgaac
    37441 caatcagcct ttagaaaact gattagttcg aggagtaaaa atgaaaaaag gttatttggg
    37501 atgaaactag aataatgcgt ataacttaaa taaaacttaa agcaataaaa tggcaagagg
    37561 gtgaggcaaa tggaagcagg aaaagtatta caggaagtaa aagcactatg tgcagataaa
    37621 aaatatgaag aagcgaaaag cctgatcgaa aagaacaaag aaaatttgga agaaaagtac
    37681 ccgatcgcac aagaatttat agaattaaaa caaggaacga tccttcaccg attcaaacat
    37741 ttttttggta taacagaata gaaaaaacga ttaaagatcg gcagaaattt gctgcatctt
    37801 taatcgtttt ctttttaaac atgcgaggga ttcaattctg attcttatat aaaaaataga
    37861 tccaaataat aagaaaaatt actgaaagcg tcaattcgat gatgtgtgtt attaatacag
    37921 acgttgtttc ccaatgccta aaagaaaaaa tttgataagt aaaatataca gcaggtaaag
    37981 aggccagtaa aactgaaaac ttcttttttg tccattttat gtaatagaaa agaatgctta
    38041 tcataataaa aaaaggaata taaaaaacaa attgaccgat cgcgatcata ctattgcctc
    38101 cgataaataa agtccatgat acaaaataac actttgtgcg aaatggcgca agcagttttg
    38161 tggatttatc cggtaaaatc tgtatcgatt ttgaaattag aggagaaact tgctataatc
    38221 aaagtgaaag aaggagtggg attttcatgg atcatgtagt gttagaaatc gatttgcatt
    38281 tgatcaataa tattcgggtg atttactatg ttgtaagtaa cagtgtcgaa caacgtgtac
    38341 tgacgaataa aataaatggt attttagcaa agaaagacgt tcaccgattc aataatggtg
    38401 aaggaagtta ttatagtatc ccagtagaaa aaattattta tacgacagtc aaagtcagag
    38461 aagatctaga taccaaaaaa gcatatgaac ctatttttac aacttattga ttgacagcag
    38521 atggaggaaa aaaatgaatc catatgaaca acttattcaa gatttgatcg atggaaaaat
    38581 cgaaaagatt gatgtaaaaa gagaagaatt aatggctttt cgagaagcgt ggctgaagtt
    38641 ggagaatcgt aaatatgtgg tgggaaaagc ctcactgaac ggcaatgtga cttatcatta
    38701 cgatccgaca cgtttatttt agtatgaagt attcagaaaa gaaccaaagg aggacgatgc
    38761 agcagcattg tcctcctttg attttacaaa agtgaaagtt ttacttattt gaatagattt
    38821 ttaaatttgt ttttgacact gtcgatattt acatctttta aaagattttg ggctttctct
    38881 ttataaggtc ctaattgttc tttatgttct tcgataaatc gttttgcgcc atcgaaattg
    38941 ccgttcttaa tcatttcctt gactttttga aataattctt cttgattcat tttgaacaca
    39001 tcctttgcta tcaacatgat tttttacatg gacaaaacga gaaaaactga tttatccaca
    39061 cgtcaataat atcaaataac gatcattttt actaaaaaaa cactcgattc tcgcttctaa
    39121 agtaggagaa aaatctccaa cttgggacgg atggaatttc tttaactgac ccatatactg
    39181 aatatataac aaggaggtag aaagatgaaa gtgattaaat atttgattgg actggcggcg
    39241 attagtggta ttttgctatt tggactgaaa tattatactg aaggaagtta tggagaaatc
    39301 cctggtatac ttgatcagct aaatccatta gttgaaaaag gagaggtcta tgtaaagaca
    39361 caaaaaccag aggaagtaaa tgaatatggt acagcaaggt atgtgcagaa agctgctgat
    39421 gccaatggga aagaacgaac ggttgaattt aatggtcttt ctgtgttaaa agaaaatcat
    39481 tatttgaaaa ttagcaataa aggagcacac atagaaacgt atgaggaagt tcctagagaa
    39541 aaagttccgg agaaagcatt agcaattatt gggtaaatca gtttttgtat taagaatacg
    39601 cccgatttta ttattcataa tttaattatg taaactaaat acaagtagta aaaataatac
    39661 aataatcccc ctgcaaaaag attgttcttt tacagggggt tcattttttc agcaagcaca
    39721 tcaaattggg atggcagggt tcgaacctac aattgcttga ttcagagtca agtgccttac
    39781 cagtttggct acatcccatt tattcaacaa aataatcata gcactttcct aaaaaaacgc
    39841 aagttatttt tcttgatcgg atagttgttg ctttactcgt aaaaggcggc gtactagttt
    39901 cttttctaat ccagcaggaa gggcaatcag ttctgctact gacaagacgg tgtccaataa
    39961 ctgatattct ttgacaggtt cattcataat atgatagatg tttgctaaac gttcaatata
    40021 ttcaaagcga gtatactctg ttcgagcaat tagaaatttc aataaatcgg tggctttctc
    40081 gtactcttga tctgcgtaat aaacaagaga ttgacgatac aatttgattt ccagttcatt
    40141 gagggtagca ggtctgcgac gctcgttcca ctcattaata gagactttac cttgaacatt
    40201 tcccttgcag tcacggacaa aaataatcgg aatttcattt ggatccattt ttttatgtgt
    40261 gaatttttcc attatctacg ctcccttcaa aggtttggta tcttgagtat aagggatttt
    40321 tgtttgaatt actagctttt ctccaaagtt agcatctgtc cacccattgc agtgaaaatc
    40381 gccgaaaaat cgttgatcgg tactgctcga ttttttacac catagggatc gttgacataa
    40441 atattttctt tgtcatatcc agtgactaca caagcatgaa caagaggagt gactcttact
    40501 tctccattat ttgtggtcca agtcataaaa tcagtttcat ctgggacttc aaaattgata
    40561 gtcacagaag tccagacagg atttccttta gatagtgctt ttttgatatc atcgagttga
    40621 gcatcggttt ttggaaaagt gtgataatcc gtttggacga tttgctgagc aagggaggca
    40681 actgggggaa catagacgac catagcccag tctccgccac tgatatcacc aacaaatcct
    40741 tcattaggat cgccatgagt cccatctgca ttgaaaacag ggacgtaatc caattgctca
    40801 gctaactggt ttttagttgt ttcataacca taaaaagata aaagcataga aagcgaagtg
    40861 acttcacagc cattttctaa agaaggagaa tcaaactggc tctctaatgg aacatctagt
    40921 aaaacttctg ctttctcttt tgtctttttc gttttttgtg ttgaactttt ttgtgcagtg
    40981 ttcattgtat gttctggaga atggatatgt aggtaataac ttgtaccgct taataaaaga
    41041 gcagctgtgc cccctagaaa caatagtttt ttgaacgttt ttttcttcat ttgaaatctc
    41101 ccttttcagc tgtttatctt tcctattata a
//
LOCUS       DAZKNV010000021        40974 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000021 DAZKNV010000000
VERSION     DAZKNV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.021"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..1189)
                     /locus_tag="ACG8M1_001233"
     CDS             complement(38..1189)
                     /locus_tag="ACG8M1_001233"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFQ0421956.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="ACG8M1_001234"
     CDS             complement(1202..1639)
                     /locus_tag="ACG8M1_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0421957.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="ACG8M1_001235"
     CDS             complement(1654..3420)
                     /locus_tag="ACG8M1_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFQ0421958.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="ACG8M1_001236"
     CDS             3684..4361
                     /locus_tag="ACG8M1_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0421959.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="ACG8M1_001237"
     CDS             4364..5491
                     /locus_tag="ACG8M1_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421960.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="ACG8M1_001238"
     CDS             complement(5691..6131)
                     /locus_tag="ACG8M1_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0421961.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="ACG8M1_001239"
     CDS             complement(6142..8175)
                     /locus_tag="ACG8M1_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFQ0421962.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="ACG8M1_001240"
     CDS             complement(8177..9880)
                     /locus_tag="ACG8M1_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0421963.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACG8M1_001241"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACG8M1_001241"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFQ0421964.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="ACG8M1_001242"
     CDS             complement(10963..11988)
                     /locus_tag="ACG8M1_001242"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0421965.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="ACG8M1_001243"
     CDS             complement(12197..13066)
                     /locus_tag="ACG8M1_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0421966.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="ACG8M1_001244"
     CDS             complement(13525..15417)
                     /locus_tag="ACG8M1_001244"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421967.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="ACG8M1_001245"
     CDS             complement(15414..17141)
                     /locus_tag="ACG8M1_001245"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421968.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="ACG8M1_001246"
     CDS             complement(17157..17807)
                     /locus_tag="ACG8M1_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFQ0421969.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="ACG8M1_001247"
     CDS             18011..18307
                     /locus_tag="ACG8M1_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0421970.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="ACG8M1_001248"
     CDS             18479..19099
                     /locus_tag="ACG8M1_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFQ0421971.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="ACG8M1_001249"
     CDS             complement(19191..20357)
                     /locus_tag="ACG8M1_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0421972.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="ACG8M1_001250"
     CDS             complement(20369..20722)
                     /locus_tag="ACG8M1_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFQ0421973.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="ACG8M1_001251"
     CDS             20850..21872
                     /locus_tag="ACG8M1_001251"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFQ0421974.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="ACG8M1_001252"
     CDS             21891..22052
                     /locus_tag="ACG8M1_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421975.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="ACG8M1_001253"
     CDS             complement(22311..22745)
                     /locus_tag="ACG8M1_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421976.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="ACG8M1_001254"
     CDS             complement(22855..24714)
                     /locus_tag="ACG8M1_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0421977.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            24715..24855
                     /locus_tag="ACG8M1_001255"
     CDS             24715..24855
                     /locus_tag="ACG8M1_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFQ0421978.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(24832..25992)
                     /locus_tag="ACG8M1_001256"
     CDS             complement(24832..25992)
                     /locus_tag="ACG8M1_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0421979.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACG8M1_001257"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACG8M1_001257"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFQ0421980.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="ACG8M1_001258"
     CDS             complement(27739..28437)
                     /locus_tag="ACG8M1_001258"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFQ0421981.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="ACG8M1_001259"
     CDS             complement(28394..30055)
                     /locus_tag="ACG8M1_001259"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFQ0421982.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="ACG8M1_001260"
     CDS             30273..31673
                     /locus_tag="ACG8M1_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFQ0421983.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="ACG8M1_001261"
     CDS             complement(31925..33004)
                     /locus_tag="ACG8M1_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0421984.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="ACG8M1_001262"
     CDS             complement(33090..34049)
                     /locus_tag="ACG8M1_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFQ0421985.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="ACG8M1_001263"
     CDS             complement(34061..35572)
                     /locus_tag="ACG8M1_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0421986.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="ACG8M1_001264"
     CDS             complement(35594..36157)
                     /locus_tag="ACG8M1_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0421987.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="ACG8M1_001265"
     CDS             complement(36163..37026)
                     /locus_tag="ACG8M1_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0421988.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="ACG8M1_001266"
     CDS             complement(37040..37936)
                     /locus_tag="ACG8M1_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0421989.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="ACG8M1_001267"
     CDS             complement(38111..39400)
                     /locus_tag="ACG8M1_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0421990.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="ACG8M1_001268"
     CDS             complement(39372..40889)
                     /locus_tag="ACG8M1_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFQ0421991.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
BASE COUNT        11810 a         8586 c         7095 g        13483 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacgttt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttt
//
LOCUS       DAZKNV010000022        40826 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000022 DAZKNV010000000
VERSION     DAZKNV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.022"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            33..656
                     /locus_tag="ACG8M1_001269"
     CDS             33..656
                     /locus_tag="ACG8M1_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0421992.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /gene="trpX"
                     /locus_tag="ACG8M1_001270"
     CDS             1106..2155
                     /gene="trpX"
                     /locus_tag="ACG8M1_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0421993.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="ACG8M1_001271"
     CDS             2152..3033
                     /locus_tag="ACG8M1_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0421994.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="ACG8M1_001272"
     CDS             3036..3806
                     /locus_tag="ACG8M1_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0421995.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="ACG8M1_001273"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="ACG8M1_001273"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFQ0421996.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="ACG8M1_001274"
     CDS             5117..6280
                     /locus_tag="ACG8M1_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0421997.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="ACG8M1_001275"
     CDS             6397..6807
                     /locus_tag="ACG8M1_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0421998.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="ACG8M1_001276"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="ACG8M1_001276"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0421999.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="ACG8M1_001277"
     CDS             9380..9664
                     /locus_tag="ACG8M1_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422000.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="ACG8M1_001278"
     CDS             9824..10060
                     /locus_tag="ACG8M1_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0422001.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="ACG8M1_001279"
     CDS             10057..10455
                     /locus_tag="ACG8M1_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFQ0422002.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11122..12066)
                     /locus_tag="ACG8M1_001280"
     CDS             complement(11122..12066)
                     /locus_tag="ACG8M1_001280"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFQ0422003.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12362..13306)
                     /locus_tag="ACG8M1_001281"
     CDS             complement(12362..13306)
                     /locus_tag="ACG8M1_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFQ0422004.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13527..14741
                     /locus_tag="ACG8M1_001282"
     CDS             13527..14741
                     /locus_tag="ACG8M1_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0422005.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14763..16778
                     /locus_tag="ACG8M1_001283"
     CDS             14763..16778
                     /locus_tag="ACG8M1_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFQ0422006.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16861..18234)
                     /locus_tag="ACG8M1_001284"
     CDS             complement(16861..18234)
                     /locus_tag="ACG8M1_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFQ0422007.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18260..18544)
                     /locus_tag="ACG8M1_001285"
     CDS             complement(18260..18544)
                     /locus_tag="ACG8M1_001285"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0422008.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18546..20561)
                     /locus_tag="ACG8M1_001286"
     CDS             complement(18546..20561)
                     /locus_tag="ACG8M1_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0422009.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20740..21045)
                     /locus_tag="ACG8M1_001287"
     CDS             complement(20740..21045)
                     /locus_tag="ACG8M1_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFQ0422010.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21134..22165)
                     /locus_tag="ACG8M1_001288"
     CDS             complement(21134..22165)
                     /locus_tag="ACG8M1_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0422011.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22372..23247
                     /locus_tag="ACG8M1_001289"
     CDS             22372..23247
                     /locus_tag="ACG8M1_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0422012.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23399..24241)
                     /locus_tag="ACG8M1_001290"
     CDS             complement(23399..24241)
                     /locus_tag="ACG8M1_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0422013.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24333..26210)
                     /locus_tag="ACG8M1_001291"
     CDS             complement(24333..26210)
                     /locus_tag="ACG8M1_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0422014.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26207..27628)
                     /locus_tag="ACG8M1_001292"
     CDS             complement(26207..27628)
                     /locus_tag="ACG8M1_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0422015.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27631..31020)
                     /locus_tag="ACG8M1_001293"
     CDS             complement(27631..31020)
                     /locus_tag="ACG8M1_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0422016.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31277..32668
                     /locus_tag="ACG8M1_001294"
     CDS             31277..32668
                     /locus_tag="ACG8M1_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422017.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32741..33388)
                     /locus_tag="ACG8M1_001295"
     CDS             complement(32741..33388)
                     /locus_tag="ACG8M1_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0422018.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33396..34082)
                     /locus_tag="ACG8M1_001296"
     CDS             complement(33396..34082)
                     /locus_tag="ACG8M1_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422019.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34088..35161)
                     /locus_tag="ACG8M1_001297"
     CDS             complement(34088..35161)
                     /locus_tag="ACG8M1_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422020.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35383..36057
                     /locus_tag="ACG8M1_001298"
     CDS             35383..36057
                     /locus_tag="ACG8M1_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0422021.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36062..37402
                     /locus_tag="ACG8M1_001299"
     CDS             36062..37402
                     /locus_tag="ACG8M1_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFQ0422022.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37551..38537)
                     /locus_tag="ACG8M1_001300"
     CDS             complement(37551..38537)
                     /locus_tag="ACG8M1_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFQ0422023.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39261..40292
                     /locus_tag="ACG8M1_001301"
     CDS             39261..40292
                     /locus_tag="ACG8M1_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0422024.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40401..>40826
                     /locus_tag="ACG8M1_001302"
     CDS             40401..>40826
                     /locus_tag="ACG8M1_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFQ0422025.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        12677 a         7413 c         7663 g        13073 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata
    10681 ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc
    10741 gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt
    10801 actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata
    10861 tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca
    10921 cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca
    10981 tatgtacgga tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta
    11041 ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt
    11101 ttagttcata ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt
    11161 tgatttgctg aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac
    11221 accattttcg tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc
    11281 agttaaataa gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat
    11341 acgtgcagta ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata
    11401 agcagcatta cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc
    11461 tttttctaca atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac
    11521 ttctgaatca ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa
    11581 tttcaatgcg atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac
    11641 acgtgatgtt ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt
    11701 tgaagcaaca acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg
    11761 catgattgac gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat
    11821 accagctgtg ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac
    11881 agccacattt tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc
    11941 tttttcttga ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc
    12001 ataagcgata cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt
    12061 tttcatgaat aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct
    12121 tgtttattca ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa
    12181 acgaattcct gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat
    12241 aatacaacca aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa
    12301 taagacagca atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt
    12361 cttaatgttt atttctccat tcattgggag tacatgttga atacttcttg aataatttga
    12421 ataaagaagt cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg
    12481 tttcttgaat cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg
    12541 aagcatcaaa atacattttc aatttattac taagatagac cggattgtag ccaaaatgag
    12601 ctgctgtttc ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa
    12661 gcatctcatt ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag
    12721 tcaattcgat cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg
    12781 tatcaaaata aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc
    12841 cgcgaaaatg aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag
    12901 aagaaagtag attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt
    12961 cttttaataa gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag
    13021 cttctttatc aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa
    13081 tttgtaaaca tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg
    13141 gaacttccgc atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc
    13201 ctcggtggat ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca
    13261 ttccttgttc acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat
    13321 tcagctagtt ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca
    13381 cgctgtactg ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg
    13441 gacatgaact tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga
    13501 taagcgctta caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc
    13561 tgctgtcagt ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta
    13621 tgtcagctac ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct
    13681 cttttatggt cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa
    13741 aacaaactgt gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct
    13801 cacaaagtta cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga
    13861 tcaattcttt ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta
    13921 tgattggttt tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag
    13981 gacagctagt acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta
    14041 ttcttgtctt gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg
    14101 gcacagcccc aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt
    14161 ttctcttgct ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga
    14221 cgacttattc tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg
    14281 caagtatggc tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc
    14341 ttacactttc tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc
    14401 tgtatgtgat tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt
    14461 acttattcaa ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa
    14521 tcttattggt tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct
    14581 cttttgcttc tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt
    14641 tgattagcgc gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa
    14701 gagtagatga agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta
    14761 aaatgacaaa tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc
    14821 gccatggact gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact
    14881 ggtacatgga tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac
    14941 cttccatgtt taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac
    15001 atccatgtgg aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag
    15061 gacatacatc agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg
    15121 gctggacagc aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg
    15181 atatcgcaaa agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg
    15241 aaacggagat tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag
    15301 aactaatatc tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg
    15361 tagaagctat ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga
    15421 aagctcgtaa acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc
    15481 aacttcaagt ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt
    15541 cttctttact gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt
    15601 tgttttttat cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat
    15661 cattcatgat caatcaatat cttttttttg acgaggaaat caataaacga acgatattag
    15721 cattaagagg acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct
    15781 tgtggttgat tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca
    15841 tcgtctaccc taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag
    15901 ggtttattta tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag
    15961 aaggaacgct tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt
    16021 gcggagatat cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc
    16081 aagaaaaata tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg
    16141 gcgcttttat cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt
    16201 tcgctgtttt attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct
    16261 tattgaatga cactatcaca cagattacta ctccatattt caaattctat gaacaagatg
    16321 ctttatgcaa actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag
    16381 ggatgttatc tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa
    16441 atgaaaagta cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag
    16501 caagcccaat ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt
    16561 atgaagaatt tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac
    16621 ctatcaaaga tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg
    16681 atagaacagg cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc
    16741 cacttgtctt aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat
    16801 atcagaagac tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc
    16861 ttaattctgt tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa
    16921 tacgacaagt aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc
    16981 tagtttccca agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc
    17041 gattttaaga tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct
    17101 attgaaagca gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc
    17161 agaagcagct ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa
    17221 gcctatcata gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa
    17281 tacagcatta ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg
    17341 tacgagtttt ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac
    17401 cccttgaagg acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat
    17461 tacagcgttg tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc
    17521 aagtgcgaca tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa
    17581 gctgaaactt ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt
    17641 tccgatccat ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt
    17701 gtttccagtg atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt
    17761 tccttcgaag accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac
    17821 taaaatgact gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa
    17881 tttatatctt gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa
    17941 agcagtaggt gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac
    18001 tactccttga gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact
    18061 gattaaacca gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg
    18121 gatcacttct gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac
    18181 gaggatggag ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag
    18241 ttcctccctt gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt
    18301 cttcgctgtc aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg
    18361 tatctttcaa agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa
    18421 catccgtatg acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt
    18481 tgatgttcat ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt
    18541 tcatatcatt cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt
    18601 aataaatctt gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga
    18661 agatgtgcct cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga
    18721 ttatcaagca gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg
    18781 ccatcttctg gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca
    18841 tactgctcca cgcgctcgat catagctttg atataacttt cttctatttt attttctgat
    18901 aatagcggct gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat
    18961 tggatcattt cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct
    19021 aaaagtttgt tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct
    19081 tttaattcga tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat
    19141 cctggtatca gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc
    19201 atgattggat gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta
    19261 gaaaaaataa tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc
    19321 tctgtaaaaa agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag
    19381 ctaatgccac ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc
    19441 gcttttctga tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg
    19501 ctcttcccta ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa
    19561 gcatattgat gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata
    19621 cgaaaatagg cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca
    19681 aattctacgg ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa
    19741 aaatcaagtg caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa
    19801 aatataatct ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta
    19861 atgtcagtga ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt
    19921 tttccaattc gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt
    19981 gcgaatcgaa gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa
    20041 taatcaatgg aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc
    20101 atcaaacgag cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc
    20161 ctaaaaccag ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt
    20221 atctttttga tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga
    20281 aaaacagaaa cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct
    20341 tgttcggtat acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt
    20401 gctcggaatt tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat
    20461 tgtttgatcg cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt
    20521 tctcttggtg ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac
    20581 ttatattcta gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg
    20641 atttttttta cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg
    20701 accaaatgtc tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt
    20761 ttttgaggtc agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt
    20821 ttcaaagtga ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa
    20881 agctgtttct ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc
    20941 ttctgtttca ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat
    21001 tgaacctctt aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag
    21061 tagttctata ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat
    21121 tcttacaaat atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca
    21181 aaattttcat ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta
    21241 atgtctcgta aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt
    21301 cttcatgata actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat
    21361 cgataccaaa gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat
    21421 cttttgtttg tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt
    21481 tgatgcggaa ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat
    21541 cgaagtaatc attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat
    21601 ctggttcgcc gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat
    21661 agctgttcgc agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat
    21721 aatgcatttc tacttctaaa atatccccta attttccgct ttcgattact ttttggactg
    21781 tcaagaagtc agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt
    21841 ttgctaatgc aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta
    21901 gtacattctt accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg
    21961 tagtgatgac aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat
    22021 attcgatgtc ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat
    22081 tgattttgtt cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat
    22141 tgccaagata agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata
    22201 tcctagaaaa gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac
    22261 acttgttatc attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga
    22321 tagtagcgga accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt
    22381 gaagaaaaac taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac
    22441 atccgtagga atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg
    22501 tatacttccc attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa
    22561 gaattccgtt tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg
    22621 attgatccta attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg
    22681 gcggatttat cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta
    22741 gatcaaatcg gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat
    22801 tctcaaatca cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc
    22861 atggctgaag aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc
    22921 gccattttta ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg
    22981 aagcatgtag aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa
    23041 caggctgata tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact
    23101 ttctcctctc aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct
    23161 caaaattttg aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc
    23221 cttcttaaag aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag
    23281 tgtttgatag gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac
    23341 ctcagcctgt ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct
    23401 aacttctgtt tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca
    23461 gtatacatgc agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta
    23521 cttctttttg aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat
    23581 gactgttgac catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga
    23641 ttctcagatc ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga
    23701 gtgtccgtcc attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg
    23761 tgaacaactt tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc
    23821 cccccgtagg ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat
    23881 tcgtttcatc aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg
    23941 tatgtttctc aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat
    24001 ctgcacctgg atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt
    24061 ggattttagc catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga
    24121 tctgctgatc cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta
    24181 ttcctgagag aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca
    24241 tttgtgttct ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc
    24301 cgctgctcct ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca
    24361 aagtacagtc cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc
    24421 ttaccgcctg ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc
    24481 aactgtcctg ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat
    24541 ggaacatatt tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct
    24601 gtcacatcga ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat
    24661 acccagctga cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct
    24721 tgatcacgaa cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct
    24781 actttaacaa atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt
    24841 gtatgcccgt tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg
    24901 ttcaaatgca tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa
    24961 ttcggatcaa ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg
    25021 tcgatttctt tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca
    25081 aatgttaaag cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt
    25141 ccttctttat cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca
    25201 ccgattgcga catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca
    25261 tttttgatgg tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt
    25321 gtttgctttt caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt
    25381 ccaacttcta aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca
    25441 ttgttgccga tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt
    25501 gtccaagtgt acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct
    25561 tcttctttag aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt
    25621 tttgtaactt tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta
    25681 tctagttctt ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca
    25741 gggaaagcta aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc
    25801 gtgtagactg catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca
    25861 gcatctgtcg ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt
    25921 gctgcatcca cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa
    25981 actgaaaatg aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg
    26041 ctgttttgga ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga
    26101 gctgctgtct cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa
    26161 ataaggaaaa ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc
    26221 ctgttctttt tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc
    26281 ctaaaagtgt atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt
    26341 tattgactac tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg
    26401 taaacggaat ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc
    26461 gataacttcc tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt
    26521 gaagcgcatc tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat
    26581 ttcctgcttt gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg
    26641 tctcgatttt gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac
    26701 caaaaccaaa atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc
    26761 ttagctgcat ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga
    26821 tcgaaaataa aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct
    26881 tttctccatt cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac
    26941 tatctgacaa ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg
    27001 aataagtgat tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa
    27061 aaggtggatc agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt
    27121 tttgattgtt ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga
    27181 cgacttctgg tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt
    27241 tagcggccag agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt
    27301 ctgcggtaaa cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta
    27361 ccgttttgcc cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg
    27421 tgacaccatt taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat
    27481 gatttttcgg cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt
    27541 ctgtttctgt ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac
    27601 acatactaag ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa
    27661 aagataccaa atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc
    27721 aattcctccc gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg
    27781 gttgtttttg gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga
    27841 cccatcttcg tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt
    27901 aaaagtttcg gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt
    27961 ttcttgtcca tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc
    28021 tccttttaat gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag
    28081 tcgattttga tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta
    28141 aatgattttt ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc
    28201 ggcaggacca gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc
    28261 aagacctttt tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt
    28321 tttctgtagg gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc
    28381 atacttacgt actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt
    28441 atcatcggaa gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt
    28501 gatttcccaa gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag
    28561 cgtataggtc atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc
    28621 atgatctgtt agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag
    28681 atccttttca cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt
    28741 agtatttttc catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc
    28801 tttgattgtt tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat
    28861 ctcttgataa ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt
    28921 atttgttgta tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc
    28981 atttgtcgta tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt
    29041 gttgtcaaat tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga
    29101 tggtataccg aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc
    29161 gttcatttga taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg
    29221 gtaatggatt tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt
    29281 tccttctatg gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga
    29341 aagtgtacca ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct
    29401 tacagttgct gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg
    29461 atcagctgat tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg
    29521 agactctact tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag
    29581 accatgtatt tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa
    29641 cgtactgtcg attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat
    29701 tagagaagta tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct
    29761 gcttgattgt gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag
    29821 caaaacgatc acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag
    29881 tgctttttgt gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt
    29941 tttcactgaa tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct
    30001 tgagtagccg acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc
    30061 gacaaaacga tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc
    30121 tgaccagtct acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg
    30181 agcattcaaa taaacatcaa acaatccggg tgtacttgtt tcttttgcat actttcgtat
    30241 cgcatagtct gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt
    30301 aggatctcca ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg
    30361 atgatcaaga acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg
    30421 atcatctgtt gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa
    30481 ggataatgta ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc
    30541 ttctatttcg tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc
    30601 aataatgtca tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc
    30661 tggatcgatt ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt
    30721 aattttcccg ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact
    30781 taagtaattt tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc
    30841 atttagcttg atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat
    30901 tgtttctaaa actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt
    30961 tgataaactc aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat
    31021 ttttcccctc ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa
    31081 acaggcgtta cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa
    31141 gggaatcaca ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta
    31201 atgagcgttt cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga
    31261 aggaaactat agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat
    31321 gactaaaaaa gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat
    31381 cgaagagatc aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg
    31441 gtatcgtctt gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca
    31501 aagttctaca aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga
    31561 gtattattgt gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg
    31621 caatcaaatt ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac
    31681 tagccttaaa agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta
    31741 cggaagacgc acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa
    31801 gaataattgt cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat
    31861 tatgtatttt gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc
    31921 tggagactct tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa
    31981 tctcttagga aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac
    32041 gattttttca gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa
    32101 tatgtcctac tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt
    32161 tcaattatta acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt
    32221 gacgatccgt gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc
    32281 tggatttcgt gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta
    32341 tttatctagc tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc
    32401 tgataaaaaa atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga
    32461 atatatcagt gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga
    32521 agatcagctg tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat
    32581 tttgaatgcc catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga
    32641 agaactcatc cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc
    32701 tgataaaaat ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa
    32761 tccaacgaga tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa
    32821 tgagatccgt caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt
    32881 cttccgacga ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca
    32941 ttggagaatc agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta
    33001 acaagtataa cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat
    33061 atttttcgat ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt
    33121 gatggactat gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa
    33181 aatatttata aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga
    33241 cttggctgat gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct
    33301 ttgcgttcga taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga
    33361 ttatacgtgg atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct
    33421 gtcaagtacc catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca
    33481 tgagtaacca taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg
    33541 acttcatatg catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt
    33601 ggctcattat ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct
    33661 ttaggataac tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt
    33721 gttgaatctt ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt
    33781 aaaaaaggaa tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct
    33841 gctcgttttt tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa
    33901 gtcggtgttt gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga
    33961 ccaatgatgc tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag
    34021 acctttgtat gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc
    34081 atttttatta acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa
    34141 acaatccgcc tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc
    34201 aaaaaacagc aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa
    34261 gagcaagcag aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga
    34321 tgaagaaatt tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg
    34381 tcatcacgta catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca
    34441 tcgcatttaa ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa
    34501 tagttaataa ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta
    34561 ttacgatccc attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca
    34621 aagcagtcca cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag
    34681 gaaagatacc gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa
    34741 ttttatagcc tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt
    34801 catgcccttt cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa
    34861 cattttcttt gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc
    34921 ctccttcaat gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg
    34981 catcctccga caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt
    35041 ctgaaagtcc attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa
    35101 taccgacgat caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca
    35161 tttgtttttc ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta
    35221 actctaaagt gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga
    35281 catctttcga taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct
    35341 ttccatgata aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta
    35401 gtagaagacg ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag
    35461 ataacacaag tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat
    35521 cttgcaatct tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata
    35581 cggaaagaaa aaatacagac tccagtattg attttgactg caaaagatag tttggaagat
    35641 aagattgaag gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa
    35701 gaactgatca tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat
    35761 gttctgaagt ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa
    35821 caagttttgc ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag
    35881 ggaatcattt tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg
    35941 acgattacag ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga
    36001 ttggataaag aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc
    36061 aatgaatgga gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc
    36121 atttgctttt atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc
    36181 atacagagaa acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt
    36241 agagatacaa agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa
    36301 cagaacaaac atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt
    36361 gatcttgtgg tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa
    36421 ccaaatcaaa gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt
    36481 aaatgaagac agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac
    36541 gaatcaagat ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc
    36601 attagcgact tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat
    36661 tggtatcagt tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag
    36721 acaaaaagaa tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca
    36781 aaatagtttg gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag
    36841 catcgctcaa gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac
    36901 aatcgctcgg aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga
    36961 atatatcgaa caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt
    37021 tattctccat aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt
    37081 tttggttatt ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt
    37141 ggattcatct gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat
    37201 cagtgaagaa gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc
    37261 gaaagagact ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca
    37321 tcatggacag atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt
    37381 gccgttgaag cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt
    37441 cacagccctt ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc
    37501 cgaaatttct ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt
    37561 ttattgcggt cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta
    37621 acatcttctg tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca
    37681 cgaataactg tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg
    37741 tcatcttcca atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg
    37801 atgacgattt cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt
    37861 ttgtggatgt cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct
    37921 tttagttgaa ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt
    37981 gtacccattg tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc
    38041 aatggatccg ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca
    38101 gtgccagttt ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc
    38161 attgtatctt ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca
    38221 tcagaaatat ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa
    38281 tcataggtat caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca
    38341 ccatccatcc gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt
    38401 ctagatgctg cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta
    38461 cgcaaccgtt caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt
    38521 aaatttttct cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt
    38581 acttataaat ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg
    38641 attaaaacaa tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata
    38701 aaatgtcatt tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg
    38761 tgatggttta atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat
    38821 tctcaatata attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac
    38881 tatttctaat acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa
    38941 taaatggaga gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa
    39001 gagcctcctg ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag
    39061 ctaaaaagag gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta
    39121 aaaatgtatc ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta
    39181 agatcaagac aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac
    39241 actattggag ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa
    39301 agcaacgtac acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt
    39361 ccctttcatt aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt
    39421 tgagaaaagt attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag
    39481 attatcagaa tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga
    39541 accaagaaac ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt
    39601 cattaaatca ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc
    39661 ttttgggtac aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac
    39721 ttttcaaaga ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag
    39781 ctagctttga agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt
    39841 gcggattaaa gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc
    39901 agattcttaa tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag
    39961 cgatgccatt tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt
    40021 ttgtttttcg ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga
    40081 gcaaaattac agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt
    40141 atgcagaact atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc
    40201 tctcatccca ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat
    40261 tagcggcatt cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat
    40321 aaactatgtt attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa
    40381 caaaagataa tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta
    40441 cgaattttca agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac
    40501 tttcagcttt cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt
    40561 tgaaacgggc ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt
    40621 ataagagttc cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag
    40681 tgcctgtcat gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt
    40741 tagaagaccc tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa
    40801 atggaacaaa atcaaaacag attcct
//
LOCUS       DAZKNV010000023        40692 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000023 DAZKNV010000000
VERSION     DAZKNV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.023"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            38..1206
                     /locus_tag="ACG8M1_001303"
                     /pseudo
     CDS             38..1206
                     /locus_tag="ACG8M1_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(1332..2411)
                     /locus_tag="ACG8M1_001304"
     CDS             complement(1332..2411)
                     /locus_tag="ACG8M1_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0422026.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(2514..2954)
                     /locus_tag="ACG8M1_001305"
     CDS             complement(2514..2954)
                     /locus_tag="ACG8M1_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0422027.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(3011..3421)
                     /locus_tag="ACG8M1_001306"
     CDS             complement(3011..3421)
                     /locus_tag="ACG8M1_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFQ0422028.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(3601..4035)
                     /locus_tag="ACG8M1_001307"
     CDS             complement(3601..4035)
                     /locus_tag="ACG8M1_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0422029.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(4135..4983)
                     /locus_tag="ACG8M1_001308"
     CDS             complement(4135..4983)
                     /locus_tag="ACG8M1_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0422030.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            5372..7138
                     /locus_tag="ACG8M1_001309"
     CDS             5372..7138
                     /locus_tag="ACG8M1_001309"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFQ0422031.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            7240..8499
                     /locus_tag="ACG8M1_001310"
     CDS             7240..8499
                     /locus_tag="ACG8M1_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0422032.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            8646..9947
                     /locus_tag="ACG8M1_001311"
     CDS             8646..9947
                     /locus_tag="ACG8M1_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422033.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            9950..10801
                     /locus_tag="ACG8M1_001312"
     CDS             9950..10801
                     /locus_tag="ACG8M1_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFQ0422034.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            10814..11629
                     /locus_tag="ACG8M1_001313"
     CDS             10814..11629
                     /locus_tag="ACG8M1_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFQ0422035.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            11780..12946
                     /locus_tag="ACG8M1_001314"
     CDS             11780..12946
                     /locus_tag="ACG8M1_001314"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0422036.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            13176..13823
                     /locus_tag="ACG8M1_001315"
     CDS             13176..13823
                     /locus_tag="ACG8M1_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFQ0422037.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            13907..14851
                     /locus_tag="ACG8M1_001316"
     CDS             13907..14851
                     /locus_tag="ACG8M1_001316"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFQ0422038.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            14986..16437
                     /locus_tag="ACG8M1_001317"
     CDS             14986..16437
                     /locus_tag="ACG8M1_001317"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFQ0422039.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            16458..17294
                     /locus_tag="ACG8M1_001318"
     CDS             16458..17294
                     /locus_tag="ACG8M1_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0422040.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            17294..17953
                     /locus_tag="ACG8M1_001319"
     CDS             17294..17953
                     /locus_tag="ACG8M1_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0422041.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            18079..18768
                     /locus_tag="ACG8M1_001320"
     CDS             18079..18768
                     /locus_tag="ACG8M1_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422042.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            18774..19730
                     /locus_tag="ACG8M1_001321"
     CDS             18774..19730
                     /locus_tag="ACG8M1_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFQ0422043.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            19774..20286
                     /locus_tag="ACG8M1_001322"
     CDS             19774..20286
                     /locus_tag="ACG8M1_001322"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422044.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(20542..21090)
                     /locus_tag="ACG8M1_001323"
     CDS             complement(20542..21090)
                     /locus_tag="ACG8M1_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFQ0422045.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(21179..22360)
                     /locus_tag="ACG8M1_001324"
     CDS             complement(21179..22360)
                     /locus_tag="ACG8M1_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0422046.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(22596..24104)
                     /locus_tag="ACG8M1_001325"
     CDS             complement(22596..24104)
                     /locus_tag="ACG8M1_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFQ0422047.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            24263..24454
                     /locus_tag="ACG8M1_001326"
     CDS             24263..24454
                     /locus_tag="ACG8M1_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422048.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            24657..25574
                     /locus_tag="ACG8M1_001327"
     CDS             24657..25574
                     /locus_tag="ACG8M1_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFQ0422049.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            25567..26640
                     /locus_tag="ACG8M1_001328"
     CDS             25567..26640
                     /locus_tag="ACG8M1_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422050.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            26788..27306
                     /locus_tag="ACG8M1_001329"
     CDS             26788..27306
                     /locus_tag="ACG8M1_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422051.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            27287..27679
                     /locus_tag="ACG8M1_001330"
     CDS             27287..27679
                     /locus_tag="ACG8M1_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFQ0422052.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            27755..28690
                     /locus_tag="ACG8M1_001331"
     CDS             27755..28690
                     /locus_tag="ACG8M1_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0422053.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            28823..29602
                     /locus_tag="ACG8M1_001332"
     CDS             28823..29602
                     /locus_tag="ACG8M1_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFQ0422054.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            29595..29912
                     /locus_tag="ACG8M1_001333"
     CDS             29595..29912
                     /locus_tag="ACG8M1_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFQ0422055.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            30156..31766
                     /locus_tag="ACG8M1_001334"
     CDS             30156..31766
                     /locus_tag="ACG8M1_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0422056.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            31923..32771
                     /locus_tag="ACG8M1_001335"
     CDS             31923..32771
                     /locus_tag="ACG8M1_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0422057.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            33002..33481
                     /locus_tag="ACG8M1_001336"
     CDS             33002..33481
                     /locus_tag="ACG8M1_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFQ0422058.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            33514..35742
                     /locus_tag="ACG8M1_001337"
     CDS             33514..35742
                     /locus_tag="ACG8M1_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0422059.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            35871..37514
                     /locus_tag="ACG8M1_001338"
     CDS             35871..37514
                     /locus_tag="ACG8M1_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFQ0422060.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(37587..38132)
                     /locus_tag="ACG8M1_001339"
     CDS             complement(37587..38132)
                     /locus_tag="ACG8M1_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFQ0422061.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(38155..38640)
                     /locus_tag="ACG8M1_001340"
     CDS             complement(38155..38640)
                     /locus_tag="ACG8M1_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0422062.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(38630..39442)
                     /locus_tag="ACG8M1_001341"
     CDS             complement(38630..39442)
                     /locus_tag="ACG8M1_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFQ0422063.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(39581..>40692)
                     /locus_tag="ACG8M1_001342"
     CDS             complement(39581..>40692)
                     /locus_tag="ACG8M1_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFQ0422064.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        13506 a         7382 c         7966 g        11838 t
ORIGIN      
        1 tttcttgcat acaaaaaaat caaggagtga gagagttatg agatattcaa ccatcttaat
       61 atcaacattt gcagccttaa gcttatcgct tactataaat cagacagtcc acacagagga
      121 gatagaaaca gccaaatgga cagaaaccaa gtgggccaac gtcaatcgaa ttacctttca
      181 ggatgaattt tcatccttca attcaggagt cgcaaaatta agaaaaggac aaacagcgac
      241 catcaaagca aaaattgact attcaggaga cttagcacct atactacaat cagctgttac
      301 atttgagaat gttgatcccg ctttgtcgat tggctatgac gagaacactt tgactatcca
      361 acacaagcaa gcgatattta ccttcaccgt tacattaaat caggacttgt taaaaccagc
      421 gctttttact gtcaaggtat cagatggact accgaacgat catcatcatt taacgccgta
      481 tagtcagcgg cagacaattg agcaagattc agctatcgac tcaggaggag atcttgttga
      541 agaaccaaca gataaaccag aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc
      601 agacggagaa cagaaaccgg aaatagaacc tggagaagaa cccgatacag aaactcaacc
      661 agagccagac aatgaatcaa aacctgaaat aacccctgga gaaaaaccag atgtagaccc
      721 agaagaaaaa ccagatgtga ctccagaacc agatacggat tctggaaacc aaacagtacc
      781 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggtagatcc
      841 agaagaaaaa ccagatgtga ctccagaacc agatacggac gcaagagacc aaggaatacc
      901 agaaaaaata aacaaaaaaa caattcaaga ggatggaaaa aaagagagta aaaaatcaaa
      961 tctagcaatt ctaaaaataa atgaagagca gctgaataaa aaatcacgaa tatttgatag
     1021 cgcccaatca gctgaaacct taaaaagtag caaggataca acctttgctg tcctgaaacg
     1081 aaaaataaac agctaccaaa atccggagag tcacaaaaca aagttatact gtggagcgga
     1141 atcattctat taagtatagc aacaatgctt tctgcaaaaa gatttaaaca aaacagatct
     1201 ctctaacatt tgaataatgt ctgtgaacgc atttttcaaa taaaaagaaa tatccagaaa
     1261 atgaccccaa aataccagat tgaaatctga tatttggggt cgttcatact ttatctttct
     1321 tcatatttat tttaagggat atctgtttct tttggaagat ggttcgggat ctttttcact
     1381 ttcaatacat ctaaaaagaa ggtaaagatc ggaatgccga caatcaagcc ccaaacgcca
     1441 aagaaccgtt cgctaacaag taagaccaca aatgtataaa aaatcggcag ttctgttttg
     1501 ctggacatca acttcggatt cagcacataa gactcaatta gatggacaat caaaatcgta
     1561 atcaggatat aaacaacatc tcggatgcct ccttgggaat aagctatgaa agatagagga
     1621 atacaagaaa tgataacacc tgctactggg atcagactta aaatgaaaat catgatcgct
     1681 aaactcagca gctgatgaaa gccaaataca gccaaggcga ttgtagtgag caacgtattt
     1741 aaaagagcga caacaaattg agcttctaat accaaaccaa atgtattgac aaacttatcg
     1801 gcaaaatagt aaatatcttg aaagaaccaa gaaaattcac tttttaaaaa caatcttgag
     1861 aatacaattg tttttttctt ttcaatcata aaaaagaaac ttaagatgaa tgacatagca
     1921 aacgccactg ccatttttcc tatatcctgt aaatagccaa gcgcaatcga agcgccattt
     1981 tgaagctgtt caaaaaaatc gtttcgctca atataagtat ggatatattg taaaacagga
     2041 tctgcatctt ttggctgatg ctcgtaaaaa ttaataacgg actggatcat gtcaaatgtt
     2101 tgatgaataa gcatcgggat atactttgtg aatgccagat agataaggta aacgatcagt
     2161 gtataaatca tgatagctaa aacacctgta gggattcgga caaatcgctg aatgatttga
     2221 acaagatgaa tcatcaaata agtaaagata aatgtgagca aaatggttgt aatcatactt
     2281 ctaactaaga aaagaacaaa aacgacaaat aataaaacag tgagacggcg tattttttca
     2341 ttcgccaaaa aacgctgata aacggtcaaa tcgacaacct ccaaataaca aaaaataaac
     2401 acgttattca ttatatgatg gaatatgaaa ataagaaaga gcaaaaagaa aaaccgctaa
     2461 atgacgttat cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc
     2521 tttttctggt cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc
     2581 aattcttcct gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt
     2641 ttttgcaacg cagcaccttg agcagtcagc gtaacattta cgattctttc atcacccgtt
     2701 tcacgctgac gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta
     2761 ccagaatcca gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat
     2821 aaaactaaca tcacaagata ctgggtatag gtaagattca gcggcttgag gaggggagtg
     2881 tagtgtctaa tgatttcttt agaggcggca tataaaggaa aacatacttg attaactaaa
     2941 tatagatctt ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac
     3001 acaaaaaagt ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt
     3061 ttgaatacgg acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa
     3121 gaccttcgat agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat
     3181 aaagggaaac ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca
     3241 attctaatgc actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg
     3301 ttgcattttc gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat
     3361 tatgcacttc tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca
     3421 taaaattacc acctttaatt atattttata caattgaatt ttacacaata taattgtgga
     3481 aagcaaagaa atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt
     3541 tctcgaatag caaacatata caaaaaatat cagagacaaa aaataatctc atcataaaca
     3601 ttacatatat ttctcaaaaa gttgttttct ttcttcaaaa attacttcac gatggacctg
     3661 atgaagcatc cataaataac caaaaggatc tctgaacatt gagttagtca caccaaagtc
     3721 catcatttct gtcatttctt gaatctctac acagccattt cgtaatgctt tattatgtgt
     3781 gtcctcgata tcagagacga tgatattgaa ccagatcgta tttggatgtt cagcagtagg
     3841 agcagtcaaa ccaagagacg tgttttcatc cagcatatgg aatctcgtac catacaaggt
     3901 aaaaatgact tcattattgc ctctagggta atctgttgcc tcaatcagtt gtatttcatc
     3961 aaagattgtt tgatacagtt ctagtgcttt caaactatca tttaatacaa aatcgatttc
     4021 cgttccttta tgcataaaga tctcctctcc ttttcagtcg aacagttact agattctttt
     4081 attataccag ctaaagaaaa cgcattcaaa aaaatagcgg atttacttac caactcattc
     4141 gattggatga taagtaaatc cgcgtcccat tacttctgct acgctgctga caatgacaaa
     4201 ggcacttgga tcgatttctt ctatcaatgg tttcattcgg gaaaattcat gatcagtcac
     4261 aacgatcaat aaaacctctt ttgactttcg attatacccg ccttttgcct ctagcagggt
     4321 aaggccacgt ccaatctcag cacttaagcg aaggcggatg tcttccaaat aatgttcact
     4381 catgaccata acagatttct ttcgattgat acctgtttcg atataagtca tgacaattga
     4441 agtgattgca atagataaaa tagcataaag aaactcttct attccaaaaa taaacagatt
     4501 aagagaaaca acgaatgcgt ctgtaaaaaa taagccaatc gaagtattca agtggaaata
     4561 ttttttaaaa atgaggggag ggatcgtcgt accgccgcta gaagagttgt ttttatataa
     4621 aatcgcaact cctaaagcaa aaatcgcact tccaaaaatg acagacaaca accgatctga
     4681 agtaatcatt gtttctggaa ctattgcaat gattaaagga aaaaccaagc ttccgaaaag
     4741 tactttaaaa aagggttttt tacctaaaaa tagaagagct agtaccaaca taacgatatt
     4801 caacactaaa ataactatag ctcggtcaaa gcctaaagca gcttccagta atattcctag
     4861 accgctgaca cctccagcag caatatgatg aggccctaaa aacatattga tagcgactcc
     4921 taatatgaag agggcaaaaa taatcttaat gtatgtccat ataaattgtc tcgtttcttt
     4981 catttattca cttccttaat tcattaataa tactcttatc ttattataac ttacttttca
     5041 ccttaagtta actttaatta ataaaaaaat taggctagtc taaattatta tgtttcattc
     5101 ttctagaata tacttctacg ccaaaaactg ttaaaaaact tttactttag aaaattggag
     5161 aaattgatcg cttaagataa attcaggaca ctaaatagta caggaagtag actaaaactt
     5221 ttaaaagttt taagtctatc tatttggcaa gtttaaaaaa taaaaattcg gtatcaaaaa
     5281 actgttaccg ataacatttt tgaaagcgtt gtcttttgct tctctatcac ttatagtgat
     5341 gacgtcatat taaaacacaa ggaggaaatc aatggataca gctgcaattt atcatcgacc
     5401 ggaaagtgaa tatgcatttc tatatacgaa tacaagattt cgtattcggc ttcgtactag
     5461 gaaaaatgat atcaaaaaag tatatgtgct atgtggagat ccatatacca taacaactga
     5521 aaaatggtat caaaaacaac gaccaatgaa aaaatgtcta agtaccaatg ttcatgatta
     5581 ttgggaaatt gaagtgacga gcgaaacaag tcgcttacag tatgcgttcc atgttgttgg
     5641 ggaagataac acggactgtt tttacggtga tcaaggaatt tttccttatc gagaaaatgt
     5701 gattactgaa ccaaattttt attttcgaat accttatttt catcaaatcg atcgattcac
     5761 tattccagaa tgggtaaaag aaacagtatg gtatcaaatt tttcccgaaa gatttgcaaa
     5821 cggggacaaa gcaaatgacc ccgaacacac tttaccttgg ggaagtaaag atccagaccg
     5881 agaagacttt ttcgggggag atttgcaagg tgtgatggat catttggatt acttgacgga
     5941 ccttggcatc aatggcatct atttttgtcc catatttaaa gccacatcca atcataaata
     6001 cgatacgatt gattattatg aggtggatcc cgcttttggc gataaaaaac ttttaaaaaa
     6061 cttgattgat gaagcacata aaagagggat acgtatcatg ttcgatgctg tattcaatca
     6121 tatgggtgtc cattcaccac agtggcaaga cgttctcaaa aacggagaaa aatcgatcta
     6181 taaagactgg ttccacatcc gttttttccc agtagattct tatcagatga ctgacttacc
     6241 agaaactgct gaaaatatcc catatgatac ttttgctttt actccattca tgccgaaact
     6301 aaatacagca aatccagaag tgcaaaaata tttgctggat atcgcaactt attggataaa
     6361 agaattcgat attgatggat ggcgtcttga tgttgctaat gaagtcgatc atcatttttg
     6421 gaaaaaattc agagaagcag ttacagaaat caaaccagac atctatatcc ttggagagat
     6481 ttggcattcc tctcaagctt ggctgcaagg ggatgaattc catgcagtga tgaattatgc
     6541 atttacagat tcgattaaag attattttgc aaaaaagaaa atcacagctt cacaaatggt
     6601 cagtggaatg aatcatcagc aaatgcttta cagagatcag gtgaacgaag gaacattcaa
     6661 cttattagat tctcatgata ctgccaggat cttgaccctt tgccaaggta acaaagaatt
     6721 gatgaagtct gtgatggcct ttatgtttct tcaaaaaggg tctccttgta tctattacgg
     6781 gacagaaata gggatgactg gtgaagatga cccggattgc cgcaaatgta tgatatggga
     6841 gaaggaggaa caagatctag agctattcgg ttttataaaa gaacttgttt ctctaaggaa
     6901 acagttgtct aagattattt ctgaaggttc tactcagtgg ctaatagtaa atgatcgtga
     6961 agataagctc tatttcacac ggaaactaga gggacagatc atctatgttt actttaatca
     7021 gtcaaaagaa ccttgggtag tagaacagga aaatgaggtg attcttagtc aaaattgtca
     7081 gttgttagaa gacgggaaag cagagatacg acaatacgga tttttgatca tgtgttgaaa
     7141 actgttaccg gtaacaacaa gaaagcgttt gcaaatgaag atttgtgccc attataataa
     7201 gggtgtaaca gcacgttgaa tacaaaggag gaaatgaaga tgaaaaaaag aagtgtgaaa
     7261 cagttgggtt tagggttaat ctctttagga atcttaggcg gattagcggc ttgtggcaat
     7321 ggtaactctt cagcagaagg ggaagccgat gaaggaaaaa cgttaacagt ttccgttgat
     7381 tctggatata aagattatat aaacgaaata aaaaacactt tcgaaaaaga aaacgatgtg
     7441 aaaatcaagc tagtagaaaa ggacatgttc gatcagttgg aatcattagc gttagatggg
     7501 cctgctggaa agggacctga cgttatgatg gcagcatatg accggatcgg tgcgttagga
     7561 cagcaaggac atctggcgga agtaaaactg ggaaatgaag cagcttacga tgaaacagac
     7621 aaagcccaag tgacttatga tggaaaaatc tacggagaac ctgcagtaat cgagaccctt
     7681 gttttgtact ataacaaaga tttagtcgat acagcaccat caacgtttaa agatttggag
     7741 aatctatcca aagacagtcg ttttgctttt gagtcagaag caggaaaaaa tacaggattt
     7801 ttagctaaat ggactgactt ttattattcc tatggtttaa ttgcaggtta cggtggctat
     7861 gtatttggtg atgatggcac aaatccttca gatatcggtt tgaataatgc aggtgctgta
     7921 gaaggaatct cttatgcaac agattggttc aaaaatgttt ggccaaaggg aatgcaagac
     7981 ataaaaagtg caggagactt cgccagccag caattcatgt ccaataaaac tgcagcaatc
     8041 attgacggtc catggcaagc gcaaacatac aaagaaaaca atatcaatta tggtgtagcc
     8101 aaaattccta ctctaaataa tggacagcct tatcaaccgt ttggcggagg aaaaggatgg
     8161 gtagtcagca attatgctaa aaacaaagac ctctctcaaa aatggcttga ttatgtaacg
     8221 aatcaggaaa atcaagaaaa attctttgaa atggtaaatg aaatccctgc aaaccaacaa
     8281 gctagggaaa cagcaaaggc taaaaacgat gaattaacaa cagctgtgat tgaacaatat
     8341 gaaacagctc aagcgatgcc aaacatccca gaaatgggcg aagtttggac aggtgcagaa
     8401 aacttgatgt tcgatgcagc atcaggttca aaaacaccaa aagaatccgc agatgaagca
     8461 gtaaaaacaa tcagtgaagc catagaacaa aaatactgat taaaatgata accgtccatt
     8521 tttataaaaa atggaacagg tgcttcagat aaaagtggca agagcgagat ggaaaattat
     8581 cttgctcttg ttgccattat cttaaaagca gtttgcggtt tagcaagttt agagggggca
     8641 ttcagatgca gcaagataaa acaagcaata tcaacgaaaa aaaaatcacg ctttgttcac
     8701 ttattccagg gatggggcag tttgtaaatg gccaagcttt taaaggtatc gtttttttcg
     8761 ccatattcgt cctattcatt ggtcagatgc ttctgggcgg atttcatgca ttggtaggat
     8821 tggttacttt gggaagtata ccaatggaag atcattcatt atttattttg attgaaggca
     8881 ctttgcaatt catcattaca atcattttct tgatttttta cggtttgaat cttttagacg
     8941 cttatcgagt agcgaagatg cgtcaagagg gcaaaaaaat caatcggacg atgaaggaag
     9001 tcatacataa tataggtgat gaaggttttc cttatctatt gacacttccc gcttatcttc
     9061 tcatgatttt tacgatcatt ttcccagtcc tagttacatt gttcactgca tttactaatt
     9121 atgacttcaa tcatattcca ccagccagtt taattgattg ggtaggggct aaaaactttt
     9181 ttagtatctt ctttttaagc tcatatcgta atactttttt tgcagtcttt tcgtggaccg
     9241 tgatttggac tttatgtgca acaactttgc aaatcaccct tggtattctc acagcggttg
     9301 ttgctcacca gaaatttatt aaattcaaac gtattttcgg tatcattttc ttattaccat
     9361 gggcggtccc agcttttatt actatcatga gtttttcgaa tatattcaac gatagcgtag
     9421 gtgccatcaa tactcaagtg attcctttca taaaccagct tccttttgta gatatcagtg
     9481 caatctcttg gaaaacggac ccgaactgga cgaaagtagc aattatctta gtgcagggct
     9541 ggttaggatt tccctatatc tatgtgatgg ttacaggaat cttacaatcg atttcagaag
     9601 acttatatga agcagcaaaa atcgacggag caaatgcatg gcagcgcttt tcaaacatca
     9661 cgcttcctgc tgtcttccta gtggcagcgc caacatttat tacacagtat acggggaatt
     9721 tcaataattt ctccatgatc tatctgttta acaatggcgg tcccggaagc gtaggcggag
     9781 gagctggttc tactgatatt cttatttcct ggatctataa acttacgact ggaacttctc
     9841 cgcagtattc tatggcttca gcaatcacgt tgattatctc cgtcatcgtt atctgtgtgt
     9901 cattgctggt atttaaaaag acaaatgcgt tcaatatggg ggattaacaa tgaaaaaatt
     9961 tcattcgagt gctcgattcc aaaaacgact ttctcacttt tttacttact tttttctttt
    10021 aatactgtca gtcattatca tctatccgct tttgatcaca gcaagtactg ccttcaagtc
    10081 aggaaatatt gcagctttta gtttagatct ttcaagtgac tggactttag gaaactttac
    10141 tcggctattc agtgaaacac tttacgggac ttggtataaa aatacattga tcatttctgt
    10201 cctaacaatg atcgtacaag tgactgtagt aactttggcg ggctatactt atagtcgcta
    10261 tcgttttatc ggccgcaaat caagtttgat gttcttttta gtgattcaga tggtaccgac
    10321 tatggcagca ttgactgcct tttatgtcat ggctttctta ttagaagcgc tcgataagta
    10381 ctggttcttg acaatgatct atataggcgg tggaattcca atgaatactt ggctgatgaa
    10441 aggatacttt gacactgtac caatagattt agatgaatct gctaaacttg atggggcagg
    10501 gcatttcagg atttttttcc agattgtatt accgcttgtc aaaccgatgc tcgccgttca
    10561 agcattatgg gcttttatgg gaccttttgg ggatttcatg ttagctaagt tcctgcttcg
    10621 aacacctgaa aatcagactg ttgctgtcgg cttacaaaca tttatttctg atgtgacaaa
    10681 ccaaagagtc tctctttttg ctgctggggc aattttgatt gcactaccga tttgtctatt
    10741 attcttcttt ttacaaaaga actttgttac cggcctgaca tctggcggaa caaaaggata
    10801 ggagcagagt atcatgcaaa catttccgtt aaactatttt tccgcattac gtacgccaac
    10861 tcaagtgttt gcgggacgca aactattatc atggcctaaa tttttcttga tatttgtatt
    10921 tttagtttcc ttgatggtca tgcctgtgac tcttttttat gccaatcaga tccaagcgat
    10981 tccattagaa caatttctat ccgttcattc gctgatcgat gaacaaggaa cccaaaaatt
    11041 ttctgaactt gaattatctg aaactgggtt acaagcatcg caacaaacga tagctgtgac
    11101 ccctgaaatt ttggtaggtg tgtctttatc tgagaaacaa caatccgatc atggaacttt
    11161 tattgatttt gagaaggaac aatgggtgat ccaacaaaag gataaatctg gtatacgccg
    11221 ctatacgatg aattatagcc catctttcca accagattct gtacgtacgc ccgaagattt
    11281 ccaacgattt ttagaaagag aattttatgc cagtaatcgt ccaacaatca ttttatctta
    11341 tagtttaagt cttggtcttg tcctatttgt catgacgagt ctcattttat tcggggcttc
    11401 ctttttcttg tggatgacaa gaaaaagcca actttcatcc attcatacat tcaaagagag
    11461 tgcaaatttg atgctgaatg ttatgggaat aggttccatg gcagcagcag ttgtagggtt
    11521 tatccacttt gactttatct tgatgctaag tgtccaaaca acgataactg tcttgctgct
    11581 tttatgggtt tttgtcaaaa caagattcaa agataagcgt gtcgaatgac aagtttaagc
    11641 gatttatgcg acaatgaatg tgaaaaaaat gaaaaataaa gtagtttttg aaaaatttct
    11701 gaaaaaatta aacttcttag ttgattcttt tcttttttag tattaacgta atagggtagt
    11761 ttttttaagg aggaaaatca tgttagagaa aactttatac aatcaattat tttcacgttc
    11821 tttctcgctc cctgtcgaag taaattattg ggacggtaca acgaaacaat acggagatac
    11881 ggacactcct ccccaaatca aaatcaatat ccatgaagaa atcccaatga aagagattac
    11941 aagtaacgct tctttggcac taggagaagc ctatatggat catcgaatcg agatcgaggg
    12001 aagtatccaa gcattgatca acgatgctta tcagcaagca aacagctttt tacgaggaaa
    12061 agattatcta aaatggctgc caaagaaaga aaaacatacg aaacaaaaaa acaaagaaga
    12121 tatccatgcg cattatgact taggtaacga cttttataaa ctttggctag atccaacttt
    12181 gacttattct tgtgcttatt tcaatacacc tgaagatacg ttggaacaag cacaaatcaa
    12241 taaagtccat catatcttag acaaactctt tatcaaagaa ggcgaaacgt tgcttgatat
    12301 cggttgtggc tggggaacat tgatgttcac tgctaccaaa gagtataatg tcaaggcaac
    12361 tgggatcaca ctaagtgaag aacaatacga tttgattacc aaaagaataa aagaagaaca
    12421 tttagaagat aaatgccgtg tattattaat ggattaccgc gaactaaaag gcgaaacgtt
    12481 tgatcatatc acaagtgtag gtatgttcga acatgtaggt tctgaaaatc ttgaaggtta
    12541 tttcaaagtg gtaaaagatt tattgaaacc aaaaggaaca gctttgatcc atggaatcag
    12601 ccgacaacaa ggcggtgcga caaatgcttg gatcaataaa tatattttcc ctggcggtta
    12661 tgtccctggt gttactgaat tagttgataa tattacaaaa aacgatttgc aactgattga
    12721 tttggaaagc ttacgtcgtg actaccaatt gacattagaa cattggacaa agaattttca
    12781 tcaagtccaa gatcaagtca cgaaagaaat gggtgattcc ttctatcgaa tgtgggatct
    12841 atatttacaa gcttgtgcag cttcatttga atcaagtaat atcgatgtga ttcaatattt
    12901 gcttgttcaa cctggaaaca atgacatccc aatgcatcgt gcataattga ggcaaaagta
    12961 ctgtttaaag actatttaaa aagaagctaa gttttatgat gctccagaag tgaacttttt
    13021 tgtctaactt ctaggattgt ctctaaagct tagtttcttt ttctttatat tttcataata
    13081 aaagtttggt tctttaattt ttaaacatga cagaaaattt tttcttcgtt atacttgtaa
    13141 tagaatacta ttttataaca aaggggatcg aatcaatgaa aaaaactgtt atttatacta
    13201 gtttatttgc agctttgttt ttagctgctt gtcaatcaaa taccaatcaa ggcacatctg
    13261 ggaatacgtc ttccagtagc gaacagcgct cttcacaggt atcggactcc tcaacaaaag
    13321 caagcacatc ttcgtctagc cagacaaaaa gttctagtga agcaagtact cagtcagata
    13381 tcaaagtgtc tgcagctcgt gcgatcgaat tgttccaaga taaataccca gatactgcaa
    13441 ttactagttt ggaattagat agtgattggg gatcttactt ctacaagata gaaggtgtcg
    13501 atgatcaaaa agaatacgaa gcaagaattg atgctcaaaa tgaaaaaatg gagacagaga
    13561 atccagaaac tctagatcga gatgaacaaa atggtcaaaa gaaaaaagaa gatggtctgg
    13621 atgttgataa attgatcacg attgaggaag cagcaaaaat cgccgtcgac aaagtaggaa
    13681 gcggtacggc aacagattgg gatttggata aagatttagg tactacttat tgggaagtca
    13741 aagtaaaaga cggcaatcaa agtacatcag tcaagatcaa tagccaaaca ggcgaagtac
    13801 tgtcaactga acaagatgat taagaatttc ttcggaaaac aagagttgat ttttctttta
    13861 gtcatgatac actagacaaa ataacttgtt tgaaggagcg atttacttga gtttagaaac
    13921 gacctttgcc aatcatatct ttgccaatcc tttgatgaat gcatctggtg tccactgcat
    13981 gactacccag gaattagatg aactggctca ttcagaagca ggagcattta tcactaagag
    14041 ctgtacgatc aatgaacgaa aaggaaatcc cgaaccacgc tattttgatg ttcctttagg
    14101 gagtatcaat tctatgggac ttccaaactt aggtttttct tattatctag agtatgctct
    14161 tgcgtatgaa aaagtgcagg aaaaccaaaa tcaaccgtta tttttttcca ttgccgggat
    14221 gagtgtccag gaaaacttgg aaatgcttga gaaaatagaa aaaagtgggt ttaatgggat
    14281 cactgaatta aatttatctt gtcccaatgt gcctggaaaa ccacaactag cttacgattt
    14341 tgaggccact tatgaaacac tgaaagaagt attcagcatc ttttctaagc cgctaggaat
    14401 caaattgcct ccttattttg attttgctca ttttgatcag atggctgata tcttgaatca
    14461 gtttccattg acctatgtca atgctatcaa cagtgtgggc aatggtttgt atatcgatac
    14521 agaacaagaa gcagtagtca tcaaaccaaa agaagggttc ggcggcattg gcggagagta
    14581 tatcaagccg actgctttgg cgaatgttcg cgctttttat acacgtttga aaccagaaat
    14641 ccaaatcatt ggtacaggtg ggattcggac aggacaagat gcatttgaac atctgctatg
    14701 tggcgcaagc atgttacaga ttggtaccga gcttcataaa gaagggccgg aaattttttc
    14761 tagaatcata aaagaattaa cgcagattat gtcagaaaaa ggatatacgt caattgacga
    14821 atttaaaggc aaattacgca ccatttcata gcaaagagac gaaggtcatg attgatcttc
    14881 gtcttttttt ataaaaaaca ctcgtctgtt cattcctgtg caagcgtact cattgtatgt
    14941 tagacgaact tgtgggaaaa taacagaggc aaaaaggagg ataatatgaa tgatgcaaca
    15001 gaattagcaa aagagcttaa agaaaaagaa tttagttttc aagaactagt tacggatata
    15061 cagaaaaaaa taaagaagca aaatcatgaa ttgaatgcgt ttgtcgcgct tgaaccattc
    15121 gagagtaatt cccacgagct attgattccc cagtcagaaa aagggccatt ggctggtatc
    15181 ccatttcctt taaaaatgct cggtcaagaa aaaaagggat ggctagctac ttcaggatct
    15241 cgtttatttg aaacacaccg agcttctcat acatctaatt atgtgcggca agcagaagcg
    15301 ataggtctag ttccttttgg acaaaccaat gcgccagagt ttggtttcaa aaatattaca
    15361 gacccagtca tctatggccc agcaagaaac ccttggaacc ttgaatgtac accgggcgga
    15421 tcaagtggag gagctgctgc tgcagtttca tcaggaatcg ttcctttagc tggtgctagt
    15481 gatggcggtg gttctattag aatacccgct tcgttttgcg gattgattgg gctgaaacct
    15541 tcgcgaggga cgatgccagt tggtccatat gcttggagag gatggcaagg agctgctatt
    15601 gatttcggct tgacagtttc tatgagagac acggaggctt tattttatgg gatgagaagt
    15661 atccattccg gtgcgccata tcaagtatcg ccagttgagt ggcaaacaca tccaagaaaa
    15721 aaacggttga agatagcttt ttgtgttgat tcaccgatcc actcacagat tagtgaagag
    15781 gcagtacttg ctgtaaaaaa agctgtagat ttccttggaa aagaagggca tgatttgaca
    15841 gagattcctt acccactaga tggtcgtaaa ctgatcacgt cttattatca gatgaatggc
    15901 gcagaaacag cagcaatgat ccgctcgatt gaaacaggca tccagcgagc tgtcagaaaa
    15961 gaagaacttg aacccatttc ttggactttg ttccaatatg gtcagaagct ctctgccgct
    16021 acttacatcg attctctgca tgtatgggat gaagcagcaa ttgtcatgga aaacctacat
    16081 caagaatacg atctattcct ttcaccaacg actgcattta ccgcccctaa aatcagcgaa
    16141 gatttgcaaa gtgatgcgat aagagcacag atggaacaca tcagtgattg ttctgaagta
    16201 gaaggtttag acgttgtttc ttccatgttt gaggagagct tgaagatcac accttataca
    16261 cagttggcta atctgactgg acaaccagca atcagcttgc ctactcattt gacaaaagaa
    16321 aacatgcctc taggaatcca atttatggct gccagaggaa gagaagattt gctatttcaa
    16381 atcggctatc tatttgaagc aaatcatcag ttccatttac caaatccatg gaaatagcag
    16441 aaacaaggag aagaagaatg aagaaaaaaa gattgtttgc tctaataact agtgcctttt
    16501 ttattttaag cgcttgcggt acagctgccg ctaatcagga agataacagc tggagtaatg
    16561 tagaaaaaaa gaaagaatta gtagtagcga cttctggcac actgtttccc gcatcttatt
    16621 ataatgatca aaatgaatta gttggttatg atgtagattt ggcaaaagag gtggctaaac
    16681 ggttaaatgt caaaatctcc tttaaagaat acaacgtgga tggacaaatc acttctgttt
    16741 caaaaagaga atcagatttt gctgcgaacg attttggtat cacaaaagaa agagaaaaaa
    16801 aattctccct ttcagagact ttcaaatatt catttgacag tatgatcgta cgaaaaaaag
    16861 atgattcagg aatccactca cttgaagatc ttaaagggaa aaaagcagct ggcgaaccca
    16921 atactagcta tatgcgttta gcggaaaaac acggagctaa attagtcaca tatgacaatg
    16981 ccacgaatga tcagtattta agcgatgtag caaatggtcg aacagatgtt attctaaatg
    17041 attattatct gcagaaaatg gccgtatctg ctttaccaga tatccctgta aaaatactgg
    17101 agaacgttta tttcaatgaa aacgaaagtg gttttttatt gaaagaagga aatgatgctc
    17161 tgaaaaagaa aatcgatggc gtattaaaag agatgaaaga agatgggacg acaaagaaaa
    17221 tatctgaaaa atattttcaa actgatgttt cagtcaaacc gaaagaaacg atggctgagt
    17281 cggtgagtga gtgatgtact ttcctctaat tgatttttcc ctcatgtgga cttcacttcc
    17341 tttcgtactg caaggcttgg tatacacatt agggattggc ttcgtgtcgt ttcttttagg
    17401 aaatctggta gggttgcttt tgacagtttt aggtcttttg gattggctgc ctctgaatgt
    17461 atttattcgt ttttatttat cgttctttag aggcattccc gcactagtcc tgctgtttct
    17521 gttatatttt gggttacctt atcaattaag tgccttaacg gcttcagtca tctgctttac
    17581 gattaccagc agtgcattta ttggtgaaat ctatcgagga tcactagcag gcgtttcttc
    17641 aggtcagtgg gacgctggtt tagcttctgg tttttctttc tttggggtat tgaaatatat
    17701 cgttttgccg caagcttttc gaatctcagt accggcactc agtaacgtag ctatggatct
    17761 agtgaaaggt acttcgttag cagcaacaat cacagtgcca gaaatatttc aaaaagcaaa
    17821 gatcataggc ggtcggacat tcgattattt ttctctctat attttagttg cactgattta
    17881 ttgggtcatt tgtatcggga tcgaaaaagt gcaacagtat ttagaaaaac gttctatgca
    17941 tcagtcaatc tgaaaaatag aaatggtgct agcgtggctg gcaccatttc tattttttgt
    18001 ttcttgtata ttctgcctag tattttaaaa ccatttcatg taaaatgtaa atcgaaaata
    18061 tgttcggagg tagaaaacat gaagaccccg ctaaccatcg aaatagaatc ctcgttatac
    18121 caatattgca tcgagcaagg cggcttggtt gtagaagaag tcacgatgcc tgatgaccaa
    18181 ggaattgtag atacgcttag ctgcttgaca aaatttgatg gaagccgaga atggcgatgc
    18241 tatgagctga aagtgacaaa agcagatttt cgctctacag ccaaactgtc atttgttgga
    18301 cattataatt attttgtttt accaagtaaa ctatatgaag aagtaaaaac tgaaatccct
    18361 acaggaatag gtgttttagt gtatcgtccg tacacggttg aagaggagat gcctgcctct
    18421 ggtacatttc tgattgcgaa aaaagcagca aagaaagagc ttgctgtacc ggaagaagct
    18481 ttgacaaacc gcttcatggc ttctttattc agggaagtaa gaaaagcaaa gcaaatggag
    18541 cgaggcgtaa aatattttcc aacagatcaa ttgtacaaag aattgaaaag acgttcagaa
    18601 aatcaagatc cattttctaa cgaacgatat tatgaacggt ttttagagga aatagctagt
    18661 caggcaatca atgagttgca agaagaagtt atcgcgcttc agcatgatta tgaatatttg
    18721 aggcaacaac agcagatccg tcggttgcct acagagccat tggagtgaaa aatatgtact
    18781 atccttattt aagaggaaaa caatttgacc tattagcatt aaaagaagca ctgtcgcgag
    18841 gattgctctc caataaaatc caaccagtga tcgaaccagt acgtgattcc gctacgctta
    18901 aaaatgtgat cgaattattt caaaaaaagc accatccaat cgctgtgatc caaaatcccc
    18961 aagtaggaca attcaaatta ttcgatcagc atgtgcacag ttggacagtc aaagaaaata
    19021 gctctgtcgt ccctgcacag atcttaacgc cagaaaatct cagtgaagta ctggattcac
    19081 ctccagcgtt tcttgttttc gatggacagc actacccaaa agatacagag gtgtggaaac
    19141 agttggcagg agttgattcg aaatttttga taccagatac tagtcgcttt cgcatctggc
    19201 tgcccgaaaa caaaattgtg atccgtgact cttttcaaac gagaaagcat gttgaaagtt
    19261 atgcagataa aacagatgac ttttttagtg atgactatct ttttttccac gcagacggat
    19321 atattggatt ttctgatttc acgatcgaag gtagccgtta tttcgataaa gggttcccta
    19381 gccgagcgct tgctatccat ctaacgtata ttgatgctta cggcaatata cgcgtgaaac
    19441 attttgtctc tgacagtaac gactctgcta aagaccaagc attgaagttt cttgaagcag
    19501 gagataaaat gaaaaaatgg atcatgcgtc accatcatca actcttgatt acttcaggaa
    19561 tgattgaatt attggctctt taccagcaac aaaaattccc tggactggga gtgttgaaaa
    19621 agtggtcact tatgcatcat ttggaactta ttagtcacct gctagatcat ccaaaagatt
    19681 ggcttaaata ttattcaaaa gttcaggaac tatatgaagt gatccaatga ttagataatg
    19741 taaatgaaaa aggaatagaa aagaggaaac tggatgtata ttcggcaaac aaggaaagaa
    19801 gaagtagaag aagtggtaga aatcattaat gccgcagcgg atttcattgc ttcgcaaggc
    19861 tctcctcaat ggcaaaacgg gcagaaacca acaaaagaaa cgattttgaa cgatattgaa
    19921 agaaaagaaa gctatgtatt aatagtggaa gatcaaattg ctggaacagc tgcattagtc
    19981 tcaagcgtgg atcccgttta cacaaaaata gatggtagtt ggaaagaatc aactggtcct
    20041 tatttatcga ttcatcgtgt cgctttagca gaaagtactc gaggaaaaaa actagcaaaa
    20101 ccgttcttag aacatttgtt gacgattgca gccagcaaaa atatccaaga tatccgtatc
    20161 gatacttatc cagctaatga accgatggaa aagaccatct attctgctgg attcacttat
    20221 caagggatga ttgaatttcc ttttgaacac ggcgaaagaa aagcatatca aataatcatc
    20281 aattgactat aaaatcatct gagcaaagat aaagacatta acactactga aaaaaacaat
    20341 catatgatag ccaagaggtt gtaacagaag tggccagctt caaaaaacaa gaaagaattt
    20401 ccgaaaatgc ttctcaaatt tttgtggaat tttagcgtat tttacgaaat agctgctttc
    20461 tgaaactccc ttcatcgaga ggtcgtgaca tagcttttgt cacgacctct cggcttatcc
    20521 tacgagtatt attcgataca tttatatcaa taatcctttt tttattttat ctgcagcttc
    20581 ttggaacgct ccatcgtttg acacgactaa aagtgagggg atagctttca aacgtttcaa
    20641 ctgtgctaaa tcttctacat aaaccgccag tctggctgaa atctgttcag atgaatctcc
    20701 acgttttttc aggcgcgatt gcaatgtttc tttagagatc gtaataaaga taggacggac
    20761 taccgtcccg aaatactcat ataaatgcca aaaaccattt gctgtcaaaa cggcgtaaca
    20821 atttcctact gtcagtttct ttttaatttc tgctttactg gaaccatatt tatgttgagc
    20881 atattggtcc cactctgcaa actcatttcc cttgatcatc tgattgaatg tattgtcaga
    20941 aacaaaataa taatcctctt gatctttttc cccaggtctt ggtgatcgat tcgtgtaagt
    21001 aatgatcttt tgttccggct gaaaaatagc ttctgcgagt gaagtttttc cagaaccaga
    21061 aggaccgata aatacatagc aataattcat tgtcatttct cctttgatga ttgaacaagt
    21121 gaaaaagctt tggaaaatat ttccaaagct tttaaaagta actttgcttt tttgtatatt
    21181 ataccagcaa gccagtcaca atagcactta aaaagctgac taaagtcgct gttagcaaaa
    21241 ttttcaatcc gtgttttgcg acaagatttc ctttttcttc atttaatccc ttcatcgcac
    21301 cagaaatgat cccgatagaa gagaagttgg caaatgaaac gaggaagaca gatataattg
    21361 ctgttgtacg ctcagtaaaa tggaaattac catttgctaa ttctgtcata gcaacaaatt
    21421 catttgtaac cagtttagtc gccatgatac taccggcatc cactgcttct ttccatggga
    21481 ttccgctgat gaaggcaaga ggggcaaaga tgtaacctag gatctcttgg aaagtgatgc
    21541 cgaatatccc gtggaagata gcattgatca tggcaatcaa agcaacaaaa ccgataagca
    21601 tagcagcaac cgtgatcgcc acatggaaac catcaagaat gtattctccc aacatttgga
    21661 aaaatgtctg ttctttgttt tcttcaatga tcagctcatc ttctttttct tctaatacat
    21721 agggatttac aattgaagcc agaatataac cgccaaataa gttcaaaaca agggcagtga
    21781 tcacatattt agaatcgatc agtgccatat aagatccgac gatcgacata gaaactgtag
    21841 acatagccga tacactcatg gtgaacaaac gtttctcaga taggaagggt aattcctttt
    21901 ttatggaaat aaaaacttcc gattgtccta aaatagcaga agctactcca ttataagatt
    21961 ccaatttgcc catcccgttg attttactta atcctagacc aacagctttc ataaataatg
    22021 gaagaatctt gatatagcgt agaataccga taatagcaga aataaataca attggcatca
    22081 atacggaaag aaagaaaggt gcacttcctt tatttgctac accggcaaaa acaaagtcaa
    22141 caccttgccc agcaaaagca agaagatgat caaacatttt tgccaataca gaaacaaccg
    22201 ctgtaccaaa agttgtacgt aataatacga aaccaagaac aagctgtaaa acgaacatca
    22261 caattagtgg tttcaatttg attgcttttt tgttactgct gatcaaaaaa gcaagcccta
    22321 atgtgacaaa taaaccaata atacctaata aataactcaa ataatcactc ctattccaaa
    22381 ttccgtttta ttttacctgt tttgcaaata aaatactaat ctttagtgaa attttcatta
    22441 cttttttaga gtgaaacgca ttcattttcc attagaaaat aaagcgaaca aaataaaagg
    22501 tttaaaaagt gtaacgtctt agtaaagtct ataaaaaaac gaaactatcg attaagctaa
    22561 tagtttcgtt ttcaacattt ataagtaaac tttttctatt ggtaatatag attttcggaa
    22621 gggtagacag gtgcgcaggt aatatcgatt cctagttttt tcaatgtttg ttcatcattt
    22681 ttattgacca tcacagtaga gtgggcttgt gctccctcaa gttcagctag tttatcataa
    22741 gcaacttgag cgattggatt cgttactgca ctgattgata aagcgatcaa gacttcattg
    22801 atgcttagtg catccaaaga ggaatgaagt gtctttgatt tcaatccttg tattgtttca
    22861 agaactaatg gtgacaataa aggaatgtca tctgcgatat gggctaaatg ttttactgca
    22921 tttaagataa ctgccgctga cgcatccatc aatgaacttg tacgcccggt aatgatgact
    22981 tcatctggta attcgattgc aatcacagca gaaggatctt ttgtaggact ttgcgcttga
    23041 atcttatctg catagtcatg ggcagggact accacgtttc ggtcttcagg acgtaaaccg
    23101 acttcttcca taatcagttt gattcgatta actgcttctt cgtcgatcaa tccttttttg
    23161 aagtcgcatt ctgtttggaa ataacgacgg atgatttctt gtttagaggc ttcttggaca
    23221 acggtatcat ccacgatccc aaatcctaca cgattcacac ccatgtcagt aggagattga
    23281 taaacagatt ctttaccagt aattttttca ataatacgtt tgattacagg aaatgtctca
    23341 acatcccgat tatagttcac agctacttta ttgtaggcat caaagtggaa ggaatcgatc
    23401 atattgacat cttttagatc gactgtggct gcttcataag caatgttcag cggatgtttc
    23461 aacggaacat tccatactgg gaaagtttcg aacttggagt aaccagctgc atgtcctttt
    23521 tggctttcat gatacagttg gttcaaggaa gtagcgagct ttccacttcc tgggccagga
    23581 gctgtcacta caacgattgg tttagttgtt tcaatatact cattttttcc aaaaccatct
    23641 tctgagacga ttttttctac gttgactgga tagtcttcga tttctgagtg tttatagacc
    23701 ttgatgtttc gtctttctag tttattgata aagactttcg tggcaggctg tccactatag
    23761 cgagtgataa cgacactgtt gattaataag ccataaccac gtaattcatc gattaaccgc
    23821 aagatatcca tatcataagt aatcccataa tcaccacgga tcttattacg ttcaatatct
    23881 ccagcataga cgcaaatcag tatttcagct tgatctttca atttttgcag caatttgatt
    23941 ttcgcatctt cttcaaatcc tggaagtaca cgtttcgcat gcttgtcgtc aactagcttc
    24001 ccaccaaatt ctaaatataa tttgtcatag tggttcactc gttccaaaat atacgctgac
    24061 tgctcttcaa tatatttttc tgaatcaaaa ccaatttttt tcactaggtt ccctccttaa
    24121 gtactaaagc attttttcat ttttttgagg attcgtcaac tggaagagcg aaattcctca
    24181 aaaaaacaaa gaaaatggtt taaaccaact tgtctagata gttattcatt ggtatgatag
    24241 tttttgataa ggaaggtgct acatgaaaaa aagacagaaa aagaaaaacg catataaaca
    24301 ctatatccgt tcgattttta ccggttatga aagaatgctt gaagatcccg aattggaaca
    24361 attgacgttt acttatctaa acgaagaaac gcagctaact cgtgatgagc atcagcgcat
    24421 tcatttcaca acaagagatc tgcctagtaa ataaaaaata agataaaggt catcggattc
    24481 gattctgtcc tatcagatgg aaagactagt tgatcgaaaa aaaggctgta ccaaattttg
    24541 gtgcagcctg ttttatggag cattgcccgc tcttttttat aacaattttt tacagaaaat
    24601 ggtactattg aagtattaat aagtgaaaaa cagatgagta agaggaggca agtagtatga
    24661 aagagccaga tacaaatgca aattatgagc cagacgaact agaggagacg aatgcggatc
    24721 aggatacagg acaagaatcg tcttcttttt acgatatcaa agaaaaagca agcatgaatc
    24781 tttcccaatt attagaagac ttacaggctt ttgaaaaagc tgtccgcgaa gaagatatcc
    24841 ctgagatcta ccgtttatac aatggccgat tgaatgaaga attaaaaaga agctcaaatg
    24901 aaaatcacga gatcgatcaa ttgctgatgc gtaagatcca tgatcgtttt ttacaggaat
    24961 ttccttttat ggaacaagta gaaaacatct cgccaacgat gagctattac aaaatcggca
    25021 cttattacca tgatcggccc acggtcggta ttgatgcaag tctgccagaa atttttgttt
    25081 tgcctaagat cgatgaagag tgggagaaat attcccaacc ggagtcaacg gactatgaca
    25141 aaaaaatcaa tgagctagac gcaaaggtga tcactgctca gacagaaatt gaacgtttag
    25201 atgaacaaat aaaagaaatc aatcgacaaa tgactgattt gaacgacaat aaaggattct
    25261 tgaatcgtaa aaaaatcgag gaagaaattc aagaattaga gaagaagaag caagtactat
    25321 ctaatgaaaa attaggctgg cttccttata ttgagacgcc tgaaacaatc cagcagcaaa
    25381 aagaagcatt gaagcaagaa gcaagagcag accagcttcg tgcagccatc gtagaaaaag
    25441 aacaaaggca aatcagacgc tatttcggta gcaaagaggg attcggtcaa gcaatccatg
    25501 aattcttgat gaattatctt ggcaatgaga atcctaataa tcaatctaat gaaggaggtt
    25561 ccgagtatga atgaacacga tgaagcagaa tggacaaaaa atgaagaaca aacagaagat
    25621 catgaagaaa cgaacacttc attggaagaa caaacaagta atcctctgga tgacacagaa
    25681 gaaatcccta tgctagagga aacaaaaata cacgaaaaag aaaaagtaac tccgacgaat
    25741 acgaatactg cagaaaacac ccatgcttac gaaataactg aaaatcccgg gtatttagaa
    25801 ggaaaagagc aagatcatca agatatcgtc agtttgattg aaacagcgga agcagaatta
    25861 gcggatttac gtatgagaaa agatttgatc gaatcagatt ttccacaatt attagaatca
    25921 tatgatcgtt ttatattgaa tgaagaacca atctccacga tcggaaagac aagcctgatc
    25981 gaatacttca cgtatgaatt actgaaaccg ttgaatgata ttggtctgga acggtcaaat
    26041 tcagcttatg acacatggaa aacaagacat ttttcgatca attatacgtt gaatggacaa
    26101 aacgaattag tcttttcctt tgtattaccg accatcgatc aacgatacca agtggaatcg
    26161 atgagtctcc taaacgtatc accagagaca atggaaatca atgtccaaga tgaccgggtg
    26221 ctttctttga tccgacactg gtcagtggat cgagtattct ctgcagggca gatcacgata
    26281 ttcaatcaca aattgaatca attattagcc catgcaagaa cacttggttt taccgttaat
    26341 cagacattac tagacaatac gaagccactt cgtttgaatc ttcagagcga atttgaattg
    26401 acgaatgaag tattggatga tatttttatc gtggcaatga aaaatccatc ctacgatatg
    26461 gaaaagatca acgaaactac ttatcaagta cgattagata aaggacagtc tttaacgata
    26521 acaacaaacg aaaaagatca aacagtcttg tcgatctcat ctggagacta cccacgatct
    26581 gtcattgatt tctttatcaa ttacgaattc ttggtcccat taatggtgag aaagtcctga
    26641 ttggataagt tggattacca gatgtcattc agataattct gttccaaagg acttgcggca
    26701 gttatccaga ataattgtca caagtctttt ctgtatgtac taaatggacg tgaataactt
    26761 gctgatgaag gagggatttc attaggaatg tccacaaata aaatagcaca gcttagctta
    26821 ttgtctgctg cttgtgtagc aggtaggatc gcttttcaat ttattccgaa tttccagcca
    26881 atgactgcta tttttttatt tatagtactt tacttaagct taaaagatgc gttaattgtc
    26941 atgagtcttt ctattgcgat cagcagtttt tattttggtg ttggaccatg ggtcatcggc
    27001 caatggatca gctatactgt tgttctgagt ttgttttcaa tcgtctgctt gagaaaaaca
    27061 gtgcaaagga atctatggtt aaagggagtc tgtttttttc tggcgggcat ggtttacgga
    27121 ataggtatga ccgtttttga tacgctgtta tatcgtttgc ctcaaccttg gatctattac
    27181 cttcaagggg tgtcgtttga tttgatgcac agtataggca atgttgtgtt ctttcttgtt
    27241 tttctgccag tcgtcaaacg tttttacaat cattcaggag gaaaaaatga aaaaaataat
    27301 ttatagtttg cttgcaatga gtgtcagtat actcattttg acaagttgca gtacaaccta
    27361 tacacaatcg gcttccaacc aaaaggagga agtaaaaaca tcgcaaaaag caacaatcac
    27421 gttacaagaa aatggtcaaa acttttcgga aaaagaagtg ttcttcaaaa aaggcgatga
    27481 tttactgagt attttgaaac gaaattttga agtcaaagaa gataacggct tcatcacttc
    27541 gcttgaaggg cactcacagg atgagaaaaa tcaactctat tggatgttta ctgtggacgg
    27601 gaaaagtgct actactggtg ccaaagagat caaattgaat gatggacaat cggtcatttt
    27661 caatttgtct aaactataag tttcataaaa aactgttaaa gggcgaatat tgccataatt
    27721 cagtgagttc agttgatgaa agaaggaaaa taacatggaa aattttaaaa aaagcggaat
    27781 gttttccgta attgctgctc taggggctaa tattctagtt gctatcagca aatttgtcgg
    27841 ctatgcaatc agtggcagtg ccgccatgct aaacgaaagc atccacagta tcgttgattg
    27901 cagcaatcag attttgctgt tattcggtga taaacaagcc aataaaggac agagcgagtt
    27961 gcatcaattt ggtgaaggac gagcaaaata ctttttcagt acaatcgtcg caatgatgct
    28021 tttcttcggc ggtggggcac ttggggtgat ggaagctttt gaaaagttga cgcatccatc
    28081 ccatgaagtg ggtaatccga tcattgttat agcaatactg ttatttggtt tggtaatcga
    28141 aggaagttcg ttacgcgtgg caatgaaaga aatcaaagaa ttgaatactg aaaaactttc
    28201 cacgatgcgc tttttgcgcg aaagtcgaca cagtgaaata ctgattattt ttacggaaga
    28261 cttgtgtgct gtaatcggtt tggtcttggc tttagcagga acaatattga cttatgcaac
    28321 cgggattgct gcatttgatg cgatcagcgg attgctgatc ggtttcttgc tgatgggagc
    28381 cgccattttc ctagcaaaag aattttatag tctgatcatc ggtgaaagcg tgacagcaag
    28441 cgatttatca aaaatcaagt tagcttttga acgtcctgag atcagtcggc tgatcgatat
    28501 aaaaacagtt catttaagtc caacggagat tttagttgca gcaaaagcag atatcgttgg
    28561 taacaaagag aatgaagctt actcggtcat caatgatatt gaaaaaaata tgcgtcagtc
    28621 tcttcctgac aagaagatgt atatatacat tgaaacagat aaatatgacc caaattattc
    28681 tcgtaaataa aacgtttatt catgaattga agcaaaaatg agaaaaatat aatcttgttt
    28741 ttaaataaaa cggctacaat ttagcgaatt tatgttacaa tgagtccgct gtttatttgt
    28801 tgtaattaaa ggagatattt taatgaacaa aaagaaaagt gcgccatggc ttcaagcttt
    28861 gcatgcagtg atgccacttt gtataagcta tataccagta ggattagctt gcggagtatt
    28921 gttgcaaaaa gttggatttg atcctctctt atcaggactg ttatcgattc tggtcttttc
    28981 cggtggcgcg cagtttttag ttgcatctat gcttacgacg caagcatcat ttgcaacgac
    29041 attattgatg gttttctttt tagaattacg ctatacatta ttaggagcaa gtcttgccgg
    29101 ttttatgaaa aaagaaaagc ggacgttttt ggctgtcttt tctcaatcac tgaatgatga
    29161 aaactatgcg gtgaactact taaagttttc aactgaccct tcctggaata aaagaaaggc
    29221 tttatatgtc aattggttct caatgactgc atgggccggt agcaatatga tcggtaattt
    29281 tttcggctcg gtgattcgag tagatgctga ccttgtccat tttgctttga cggccatgtt
    29341 cattttcatg tttatcatgc agatgaaaag cgcactactg atctttacag gtttattctc
    29401 aggcgtatta ggggtcgtat tcatggtatt attccaaaat actttcggat tgattgcagc
    29461 aacagtcatt gcttcatttg ccggatttat gctggagaag gcattcaaaa aagaaaaagc
    29521 taagaaacta agagaccgcg gtaaagatgt caatgagccg ctcttcaact tcccggaaca
    29581 ggaggccaat caccatgact aaactatatt tgctactttt agttgcttgt ctgttcatcg
    29641 tggcatatat cccgcgcttg ttcccgatgc tttattttac tcatcgaaaa gtgccatcct
    29701 ggttcagtga ctggatgaaa tatgtaccgg tggcattatt tgcggcgtta gcttttaaag
    29761 atgttttcat tactcatgaa catctggata ttgcttggaa tatcaaaata gctgcaatga
    29821 ttctagtagc aggcgtggct tacaaaacac gttcgatggc gttgtcagtt ttgacaggac
    29881 ttgcgtctgt ctttttgctg tctatgcttt aaactgtttt attttattaa aaacagagat
    29941 tgcgacataa gttgttcaaa ctgatctatc cgaactgcat ttgcaacagt caattctgga
    30001 tgcaagttta ttcgtaggga taaaaaagat tagtgttggc ttatgatgca agctcttttt
    30061 tattttagga attagagagg gatttgtcct tctatgattt tttgctataa tagggaagat
    30121 gtttatttta tgaaagaata gttgagggaa tttaaatgaa taaaaaattg atgcaaggaa
    30181 cattttggct aacctttgct aatcttctat gtaaagtttt aggggtagtc tatttgattc
    30241 cctggctaag tatgatgggg aacaatcaag atggtatgct tgctacgaca ttgtataatg
    30301 ttggctatct tccttatgga ttgttcctga tgcttggtac agtcggattt ccaaatgcga
    30361 ttgcaaaaaa agtagctgta gccacaaaag aaggagataa cgctgcttgt cggctgattt
    30421 ttagaagtac gatcaatatc atgtttgtca tcggtatcgc ctctgctgca ctgatgtatt
    30481 tatttgctcc tttactagcc ggaatcagtc cgattgctaa cgttaataat gggatactag
    30541 ctatcagaag tttatgccca tctttgattg ctatcccaat tcttagtgca atgagaggat
    30601 atttccaagg aaaaaatgat ctgcggcctt atggaacttc tttgattatc gaacaggctg
    30661 tgcgagtgat cgttatcttg gctggtactt attacttgcg cgtattgact gacggaacca
    30721 tattagaagc tgtattgatc agtacagtcg cttctttctt cggtgggtta gctgcgatta
    30781 tccatatgta tatcgtcgga cgcagaaaag acttcttcga acttaaagat tttttgattt
    30841 ccagccgtta tttcgaaaga gaaaaccgat ctgcctctgt ctctatcatt cgggaaacac
    30901 taccgtttat ttttgtcggc tcagtcatta ctatcgttca aatgatcgac caagtaacga
    30961 tgaaaccact gcttcacttt ttccgtccag agatcgcaga tcagcaactg gaattcttat
    31021 tcagccgtgc ttctgtcaat ccaaataaat tgacattgat cctgatctcc atggtaggaa
    31081 cagtagctat aagcagcttg ccaatattaa gcacgatgaa gaaaaaagat cggatacaaa
    31141 tcgaaaaaac agtaggagat agtttttcga ttgcgttatt gattcttctt ccttcattga
    31201 ctggaatgtc tttattagct ggaccactat acacattgtt ttttggctat gatcctgaaa
    31261 gtgtcggata tttccaaatg gctttgctag cttctttgtt tttctcttta ttcacgatcc
    31321 tatctacgat gcttcaatct ttgaatcacc atcgttttgc gatccgatta actgtagaag
    31381 caattatcct gaaagtcatc ttccaagtaa tcggattagg attagttggc ggatacggga
    31441 tgagcttatc aaatggctta gcattcggta ttgtctttgt tcgcggctat cactttatgt
    31501 gcaaagaata ccgaatagca cctttagcaa agatcagcaa ttttttctta aaaactttcc
    31561 gctccaccct gattatgctt gcagtatgtt ttgccgtttt ctttttgctg aatcagcgat
    31621 tgtcaatgga atcaaaaagc tatgcaatga tttattgtgt ggctgtagga agtattggcg
    31681 gcttagtatt tttattttct caattcggaa aaaatgggtt tcgaatgttg aaaaatgtta
    31741 aacatcatag cagaagcaaa gaataggtta actaatcgtt ttttgctgtc acttgaaaaa
    31801 cggcaactcg tatgattacg cttgtcgttt ttctattttc caattttagt ttcatatcta
    31861 atcttactta tgatatagtt ataaggtctg gaaaaattct ttgaaacgag gaaattaaac
    31921 acatgaaact tgcagtagtt acagatagtt cggcatatct gccggaacgt atcaagaacc
    31981 atcccgactt attcgttatt ccaatccctt tgattatgga tgggaaaatt tataacgaag
    32041 gaatcgatat cgaagcggat gaatattatg gacttttaaa aaacagtaaa gattttccta
    32101 ctacttcaca acctgtcgta ggggaagttt tgggtttata tgaggaattg aaagagaaag
    32161 ggtatgacac gattttaagt atccatcttt cttcagggat ttctggcttt gtcaacacat
    32221 tatttgcgat gaaagatgac atcagcggag taacggtcat tccttatgac tctaagatca
    32281 ctagtatgcc gatgggacac atggtagaag ctgccttaga cttaaatgat gaaggtcagt
    32341 cccttgatga aatacttgca catatcgatc gaatccgaga taatacctac gcttatctga
    32401 ttgtagatga tttgaacaat ttagtacgag gaggacgttt gacaaatggt gcagcgctga
    32461 ttggcagctt attaaaaatc aaaccgatcc tgacattttc tgaagggaaa attgttttat
    32521 tcgaaaaaat ccgttcaagt aaaaaagcat ttgctcgagc tgaagaaatt attggtagaa
    32581 gaaataacga aatacaaccg ccagtcaaac tttacgtgat acatgcaaat aatttagaag
    32641 tagcgattgc ggagaaagag aaattgcaga aaaaatatcc aaatgcagaa atcgaaattg
    32701 gtcatttcgg accagtcatt ggtacacatt taggtgaaaa agccatcggc attgccattt
    32761 cagcgcaata attcctttta ttcaaaaaac ataccaaaaa tattccaaca tcatcttgga
    32821 ctttctacat gttactaatg agcgtgtaaa agaacgagat ggtgttttta tttctatcaa
    32881 tgaagctctt tttctttgca atcctcactt caatcctcta taatgtcgca tatagtttag
    32941 taaatgagta aactactaat ttacttattt actaaaaata aaaggatgag gagttaaaat
    33001 aatggaaata ccaacaaatt taaaacataa accagtaatc gttgtagaag actatgataa
    33061 agttgatgga agaaatgcat taaatacgga tgcaaaaggg ctttcactgg gccttgctca
    33121 gtggaatgat cgtggaaaag tcgatatctc aggcaaggta tggcgacata ctggagaaaa
    33181 atggtcacga cagtcggaag aattaccaat cacacgtatt ttagatttag cgatcttagc
    33241 tgcacaagga agtttatact tccaagatgc ttatcgttat gaaaaatttt atgatccaga
    33301 aaatccagtc gtagacatca ttggattaca agggaaccga atgacggtag aagtagatac
    33361 caaaaatcca aagatcgatg aagacatcat tttgtattac gatacactac aaaaagacgg
    33421 agaactgatt ggggaacgat tccgtatttt aaaacgtctt ttagatgagc taggatatta
    33481 atagacagag atgatcaaaa ggggaagaga agcatggaga atttctcact aacagaaaac
    33541 cgaacctttt cacggctaga aaagcaaatg atctggaaga aaccgaaaag ccatcggaca
    33601 agtgcagaag aatggcggat cgcctccgaa atcaaaggga attggcaaga tcctgaaatg
    33661 aaaatcagta acgtactttt ggaaggagat gccgggtcgg ggaagacaca attagccaaa
    33721 gcactatctg ctgatctgca acttccctat acaaaagtga cctgttttgc agatatggac
    33781 aaatcagatg ttttcggagc cttattacct gtagtagatt ctaataagga acaagaccaa
    33841 gaattactag aagctattta ccaaacagat acacttgaag ctgtactgac actgatccag
    33901 aaccattacg gcattgatcc tttttctgct aaagaaaaat tagcagagct agttcaaagg
    33961 atcgaagctg attatccaga tgcaatccat tacagctatt acccttctga aatcgttcga
    34021 gcgattgaaa aaggatattt attagagatt caagagccga ctgtcatccg agatgcctct
    34081 gttcttgtgg cacttaactc agcgctcgaa ccaaatggga tgttgaattt accgacagga
    34141 atcattcgtc gccatccaga ttgcgtcatt gtgatcacta caaatcgaaa ttaccaagga
    34201 aatcgcccat taaatgaatc tttaagagat cggatgcaac atgcggaaaa aatggatctt
    34261 cctgccttag aagtcatggc agaacgtgcg atggcgaaaa ctatgatcca aaaacaagaa
    34321 cttctcttaa agatggcaga gattatccgt ttgttggatg aaactgcaaa agctaacgcc
    34381 atcaaaggtg tagcaggaat gcgttcttat ttttattggg caaataccta taagcaagga
    34441 caagatttac tccagtcgat ttatccaaaa gttttgtata aattatccac tgattcagat
    34501 gaattggcaa ttcttgaaca agctttgtct gacagtggat tgctactgga acttcaggac
    34561 atattgagaa aagaaaaatg gggtcatcct caatctgagc atacaaaagg aagaaccatt
    34621 agcgccgaag aagcaaatga acgaaacatc actgaaaatg ctgaagaaat tctgcgctta
    34681 gatgaaaaga aatcgttgtc tgctgaagaa ccaaatgagg gagaagagaa acaagaagaa
    34741 acaatagaaa aaaacgagat tcctcctcaa atgcaaaaag aacgcagtag cgatatcgaa
    34801 ggaaaaaatc aaaaagaaca acaaacagga gatgattctc aagaaatgtc tgcttctgac
    34861 atggaagcac atgataagga aatcaagaag caactgaata aagaagcgcg acaaatcatg
    34921 aaggaaacga ttcatgaaaa agaaggtctc atcgttcacc gaccagcttt ccaaggaaaa
    34981 acgccggaag cacgtgagct acacatgcaa gtaatgccaa tagtagaatc acttagccgg
    35041 caaattttag agttactgga taatgaacaa acagagacgt accaaaaagg aaaatacgaa
    35101 ggtcagcggt tcaatgcaag caaagtagca tatggtgatt tgagaaattt tgacaaaaag
    35161 aacccgccac atgagcaacc ttctttagcg gtagctgtac ggatcgatga atctgggtca
    35221 atgatacggg atgatcggat cgaagcggca aaaaaagcag cgattgccat tgccgaattt
    35281 tctaagaaag tcgatatccc attgttgatt tacggagata cagcagaccg ttcgtcaaga
    35341 gaaaagactt ctttgttttc ttataaagaa tttgaagacg gatttcaatg gttaaatgaa
    35401 aaattagtca ctatgaaacc aaggcaaaac aatcgtgatg gtgctgcact tcgtttagca
    35461 gcagaaaaat taaacagaca atccgcaaca accaaactgt tgcttaatat tagtgacggt
    35521 cagccaaaag cgttgccgga ttatacaggc aaaaaagcaa aagaagatat ccagtctgtt
    35581 ttgaaagaat atgaacgtca aggaatccta tttgtctccg cagctattgg ccaagacaaa
    35641 gaagaaatca agtcgatcta cggtgaaagt cgttttgtag atattactga cttgaatgaa
    35701 tttcccaagc aaatgattca actgattgcc cgctatctat gataaaataa agctcaacga
    35761 acgcacttag cagattcgtt gagcttttcg tttctagtta ccggtaacaa ggatacttct
    35821 aaaatagaat cggttataat caagagggac cgttaaagga gtgaaacgat atgatacaag
    35881 aacaaaaatg gtggaaagaa gcagtaggct atcaaatcta tcctgctagt ttcaaagata
    35941 gcaatggcga tggtcaagga gacatcaatg ggatccgtga aaaacttaat tatttgaaag
    36001 atcttggtat cggctttatc tggatcaatc cgatctatca atctccattt gtcgataatg
    36061 gttatgacgt aagtgactat caagatatag aagagagatt cggaacgatg gaagattttg
    36121 atttattgct aaaagaagca catgaattag ggatcaaagt gattatggat cttgtcatca
    36181 accatagttc ggatcagcat caatggtttg aagaatcgaa aaaatctaaa gaaagcccgt
    36241 atcgcgatta ttacatttgg gtcgacgggg tagatggcaa agaaccgaat aattggacat
    36301 cgattttcgg cggttctgct tgggagtatt ctcatgaaac tggacagtat tatctgcatg
    36361 tttttgcaaa agaacaacca gacttaaatt gggaaagcga gaaattgaaa gaagaactat
    36421 tcaatatgat ccgatggtgg ttggataaag ggatagatgg atttcgttta gatgcgattt
    36481 ctcatgtaaa aaaagatgaa tattcagtaa aagccacaga gaaccctttc tcaccctttc
    36541 aaaatgtctc aggaatcgaa gaacatttga ccgatttgaa acatgttttt gaagagtacg
    36601 atatcatgac tgtcggagaa gcaagtggtg tcactgcaga agaaggacca caatgggtag
    36661 ggaaagacgg ttatttcgat atgatattcg aatttgatca tatccatatc tggcagcaag
    36721 aaaaagaagg gcaattagat gtccttaaat tgaaacttgc attaagcgct tggcaaactt
    36781 cattggatgg tatcggatgg aacgctttat atatggaaaa ccatgatgtt cctcgtgccg
    36841 tttcagtgtt tggagatact cgtcccgatt tttgggctat gtctgcaaaa gcaatcgcta
    36901 tgatgtattt ctttttgcaa ggtacgccat ttatttatca aggacaggaa atcggaatga
    36961 cgaatatgcc ctttgaatcg atcgatcaag ttgatgcagt agattcgaaa agactttata
    37021 aaaggctgct tgcggaaggt aagacaagag aagaagcatt ggatatcatt cgtgaaacaa
    37081 cgagagacaa cagcaggaca cccatgcaat ggacttcgga acaatatgct ggtttttcta
    37141 cacatgaacc ttggctgatc actaatccaa ataccaaaac gatcaatgta gaacaacaag
    37201 aatatgaacc agagtcggtc ctgcaattct ataagaacat gatccgcatt agacaaacca
    37261 ataaaggtct gatatacggt tcttataaag aatatcttca tgaacatcca caactttatg
    37321 tctatgaaag atatttagaa gatgaacaat atcttattat ggtaaactta acagaatcac
    37381 ttgctgacta tgaacttcca aaagaagcag atcagtcctg gacattactc ttgtcaaatt
    37441 cctctagcgg agaatttgaa gctaaaggca tactagcacc ttatgaagct cggttatata
    37501 aaacaaacaa gtaaaacttc ctcgttaaag ttcattagtt ggactttgcg aggaagtttt
    37561 tcagattgct ctgtcaatta ctcatttcaa taattcgctc taggaccacc gatatattta
    37621 ggacgagagc gaagggctgt cacgtgagct tgtccaaggg ttttcaaacg aggtctgaca
    37681 ggtacttgga catgtttgat atgcataccg attgatgtgt caccgatatc gataccggct
    37741 tgtccaacta cgtgttccac ttcgacagga tcattgaact ggtcaaaagc agcaacagaa
    37801 caagcacctc cagcatgtag tgcaggaaca acagagacaa tttcgaaatt ttttgcttct
    37861 gccactgttc gttctactac taatgctcgg ttcaaatgtt cacaaccttg gacagctagc
    37921 gcaatttctt taggatccaa caactctttt aacgtacgga tgatccattg accaacttcc
    37981 gcactggaat tttttccaat atgtcctcca acgacttcgc ttgtgctgca tcctaaaaca
    38041 aaaagatcac cttttttcaa gtgtgcctca gccaatatgt cattaactat ttcagtcaat
    38101 tggtctttta attctttttc tgacaacttc attttctaaa accttctttt tcaattaata
    38161 ttgcttccgt gcttgaatac gttgaagact tgcagttata ggaaaggcaa gtcccattcc
    38221 aatcagattt tggaagatgt ttcctggtat agaagccact ccagccggcc aatcatataa
    38281 aatccaaccg gcgataccat agccgatgat cataactaag cttcctaata aaagccctaa
    38341 tccccacata cgagtagaag atttgctgaa agaaccagca acatatcctt gtaacccgtg
    38401 gatcactaat gaaaaaactg cccactgcgg atatcctgaa atcaaatcga tcaatagacc
    38461 actggaagca ccaacaacta atccacccgt tggaccataa agaaaagcag cggtatagat
    38521 cccggcctcg cataatgtca caaatccatt cgtagccggt acagggatca aaattgttaa
    38581 tgaaagggca actgtcaacg caatcagcat agcatagatc gttaattgct tagttttcat
    38641 ttctcattcc tcctttttga ataccgccag accagacact tccggtatga tcgttcatca
    38701 gcacgccatt agaaatacaa tgggcaacaa attttttact ttctgctact gctttggtaa
    38761 aatctgcccc taacacaaga ttcgctgtta ttgcagaaga aaaggcacaa ccggccccgt
    38821 ttactgttgt agtgtcgatt tttttatgag aaaatacctc ataatgatca attgaataga
    38881 gaagatccac agcttcatct ccagccatcc ttgtgccgcc tttgatcaca atgttttttg
    38941 ttcctgaagc agtgagttct ttagcgagat ggatcatttc tgttaacgaa gagggaagag
    39001 cttgaccaga aagtaaagca gcttctgcca aattaggcgt aatcatcgta acaagtggaa
    39061 aaagttcttc gatgagctgc gaaatataca attgattgat cacagcttca gtttctttga
    39121 atgccaaaac agggtctaaa atgattggga tattttgttt tgtttttatg aagtctcgaa
    39181 caaccatgat tgcttcactt gaattcaata acccaatttt gataccatct aatgaagtca
    39241 ttttatcaat cgaaactaac tgtcgtttaa gcaattccaa agatatagat tccagcataa
    39301 atcgctcatt aatatctagt gcccctatag aagtcaaggc gcttagtccg aatagaccaa
    39361 aattctcaaa agtttttaaa tctgtttgga ttcctccacc agcaaatgga tcagaaccgc
    39421 caattgtcaa gattcttttc ataacatttt cctccatgaa taagagtata acgaaatttt
    39481 caaaaaagaa aaacagccaa ttggcatatt tttatctcat ccaatttaaa aaaacaaaaa
    39541 gaaaagaaag accaaaatgg atctttcttt ccttaaatag ttaggacttt tgtgatttta
    39601 attctttctc gatttgaagc cgttgcactt tcattgtagc tgtccgcggg attgcatcaa
    39661 aatcacggat gatagggacg ttcaagcgag gaagttcatg gacttgctcc caccatcgat
    39721 tccaatccat ttctttatca ggagctaaag caataatcgg ttgtggagaa tgatttttat
    39781 cccttacaat cactacttct gccaaaaaat ctaacgaatc taataaaaag tcttcaatag
    39841 ctaatgtact attgatcgtt tcgatcaaat ccacttgccg atctttcaaa aataggtggc
    39901 catgcttatc cataaaaccg taatctccgc tatcccacca atcgccataa acattttcct
    39961 ggaaccgtgc atcttccttg taataagtca aagcccgtcc tttagacagt aattgtatat
    40021 gaccatctgt gttttcaggt aggacattcc caactgaatc tgtaatccga gcgcttgtca
    40081 tgtcttccag tccaacgccc atatctcttg catcacttgt tttcaaactc tctagtgtat
    40141 gagccttaag aatcattggt ccgcattcac tttggccata tacttgaaga aataccgcat
    40201 cctgtgccat cgacgttcgc aaaaatgtct tcattgtctg gttgtttata gcatcaaaag
    40261 tggagtgata gtatcggata cccgaaaaag cttctggatg ctccttagca gtaaaacgcc
    40321 actgaacaaa gttattcgga tgggtctcta gtgcaattgg ccggtgagct tccaacatat
    40381 gaacaacttt tgaactttgt gcgtttgcta aaggcatcat aggaaatccc atggacatca
    40441 aagaagagat accaatattg aatctggaat gcactggaga gatgtgaaaa gcgattaatt
    40501 tcttttccga aatttttgtg aaaactgttt tttgccattt cgtccgccat cccatagaat
    40561 gagcagaatg acaaataagt ttagggatac cagttgtacc agaagtatgg gtcatataag
    40621 aaatttcatt tttgtctaaa aatgattgag aaacagacaa agcaggttgt tccattaaat
    40681 aaagaatagg aa
//
LOCUS       DAZKNV010000024        38063 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000024 DAZKNV010000000
VERSION     DAZKNV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.024"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(40..531)
                     /locus_tag="ACG8M1_001343"
     CDS             complement(40..531)
                     /locus_tag="ACG8M1_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422065.1"
                     /translation="MTDKTGNLPKLAPKTSQTKSKKDEKIKNAVKKKSVKESSSLLLD
                     IPMSTFDEILDDNTDETSVKIASHVGMNSQNDSFYHLLNSLRELEDKKNQVIASKAPD
                     LTTDLDAEIIQVKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISEQKK
                     SDD"
     gene            614..1999
                     /locus_tag="ACG8M1_001344"
     CDS             614..1999
                     /locus_tag="ACG8M1_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFQ0422066.1"
                     /translation="MKKSKKTFGTLLIAVMQIIGITASLITINPQVTHADGIATYDAQ
                     FNCSTEGSQGSSGSGKDSDGNETGSGAVSGDVAKNIDDIYKFMNGEYGLSGATIAGIL
                     GNWKQESGNDPRTVEGYYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVNWAKKN
                     FGGAWWTTEAQLDFMFKGDGGFVAILKDYALNASDDVVANAVAFHKNWEISADSESAV
                     VAVRGGNAKEIWEYMKSKGMDGAKDVSKINKIAGGTSTGGGSNNSSSSASGTVEDACA
                     TTDDANSGSGSMGKEGKINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFN
                     GIYQGQCTELTWAYMSQLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDG
                     WLWAVGDAGHTGVVIAVFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFS
                     GVGKAKFEIEK"
     gene            2022..2549
                     /locus_tag="ACG8M1_001345"
     CDS             2022..2549
                     /locus_tag="ACG8M1_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422067.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSDKEKIEYYKPFTFKLTNFGIKTSSSGLYEVLTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            2536..3099
                     /locus_tag="ACG8M1_001346"
     CDS             2536..3099
                     /locus_tag="ACG8M1_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422068.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            3521..4258
                     /locus_tag="ACG8M1_001347"
     CDS             3521..4258
                     /locus_tag="ACG8M1_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422069.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(4275..4691)
                     /locus_tag="ACG8M1_001348"
     CDS             complement(4275..4691)
                     /locus_tag="ACG8M1_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422070.1"
                     /translation="MNKKRKLSVLITLISILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            5083..6330
                     /locus_tag="ACG8M1_001349"
     CDS             5083..6330
                     /locus_tag="ACG8M1_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0422071.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            6600..8990
                     /locus_tag="ACG8M1_001350"
     CDS             6600..8990
                     /locus_tag="ACG8M1_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0422072.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKIKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            9039..10874
                     /locus_tag="ACG8M1_001351"
     CDS             9039..10874
                     /locus_tag="ACG8M1_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0422073.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            10949..11806
                     /locus_tag="ACG8M1_001352"
     CDS             10949..11806
                     /locus_tag="ACG8M1_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0422074.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            11796..12905
                     /locus_tag="ACG8M1_001353"
     CDS             11796..12905
                     /locus_tag="ACG8M1_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0422075.1"
                     /translation="MKNKILLFLTLICTLVLTIYPASQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKPETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVLGALASLKVLILLIKEFRKA"
     gene            13244..14044
                     /locus_tag="ACG8M1_001354"
     CDS             13244..14044
                     /locus_tag="ACG8M1_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422076.1"
                     /translation="MVEISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIEGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            14150..14938
                     /locus_tag="ACG8M1_001355"
     CDS             14150..14938
                     /locus_tag="ACG8M1_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422077.1"
                     /translation="MSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWISAVGEEN
                     IEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVSWEMNNQ
                     YKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYAEYLKTE
                     RDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALSQYSSDE
                     EVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            15051..16478
                     /locus_tag="ACG8M1_001356"
     CDS             15051..16478
                     /locus_tag="ACG8M1_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HFQ0422078.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTHGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTVPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCRSCPLLKNCTLSTKHQKIVTRHVWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKAKKPM
                     AFYLKFLQRLTKRSWQLSHSFLSTV"
     gene            16709..17578
                     /locus_tag="ACG8M1_001357"
     CDS             16709..17578
                     /locus_tag="ACG8M1_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFQ0422079.1"
                     /translation="MKKKEFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            17598..17945
                     /locus_tag="ACG8M1_001358"
     CDS             17598..17945
                     /locus_tag="ACG8M1_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422080.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            17958..19220
                     /locus_tag="ACG8M1_001359"
     CDS             17958..19220
                     /locus_tag="ACG8M1_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422081.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            19300..20676
                     /locus_tag="ACG8M1_001360"
     CDS             19300..20676
                     /locus_tag="ACG8M1_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFQ0422082.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKLVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     ADSEPQTSNNTNNEQPISSKTKPKTTDPKVSVNVTITTDKSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            20673..21302
                     /locus_tag="ACG8M1_001361"
     CDS             20673..21302
                     /locus_tag="ACG8M1_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422083.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRTKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            21321..21800
                     /locus_tag="ACG8M1_001362"
     CDS             21321..21800
                     /locus_tag="ACG8M1_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422084.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            22359..22958
                     /locus_tag="ACG8M1_001363"
     CDS             22359..22958
                     /locus_tag="ACG8M1_001363"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFQ0422085.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            22974..23450
                     /locus_tag="ACG8M1_001364"
     CDS             22974..23450
                     /locus_tag="ACG8M1_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422086.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            23467..24369
                     /locus_tag="ACG8M1_001365"
     CDS             23467..24369
                     /locus_tag="ACG8M1_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422087.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQANNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDDK
                     KASDDVLATIKPSQSQFEVFYTVKENNPVRKLTLVFNVDGEEYYKDVKINKASTKKIV
                     ESAKKEVATEESTTESSSTVEVELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQRINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            24442..24636
                     /locus_tag="ACG8M1_001366"
     CDS             24442..24636
                     /locus_tag="ACG8M1_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422088.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKTRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            24741..25169
                     /locus_tag="ACG8M1_001367"
     CDS             24741..25169
                     /locus_tag="ACG8M1_001367"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422089.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNEETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            25404..25991
                     /locus_tag="ACG8M1_001368"
     CDS             25404..25991
                     /locus_tag="ACG8M1_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422090.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            25991..26890
                     /locus_tag="ACG8M1_001369"
     CDS             25991..26890
                     /locus_tag="ACG8M1_001369"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFQ0422091.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVADATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            26890..27804
                     /locus_tag="ACG8M1_001370"
     CDS             26890..27804
                     /locus_tag="ACG8M1_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422092.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPANSGIGIVLKAIDEEEIEDFIPAEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCEGYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     DARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNASNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKEAE"
     gene            27856..28071
                     /locus_tag="ACG8M1_001371"
     CDS             27856..28071
                     /locus_tag="ACG8M1_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422093.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLQQFWLNNFSYKDFIKEKANRLY"
     gene            28261..28515
                     /locus_tag="ACG8M1_001372"
     CDS             28261..28515
                     /locus_tag="ACG8M1_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422094.1"
                     /translation="MKKEELIDMFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLISDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            28727..29743
                     /locus_tag="ACG8M1_001373"
     CDS             28727..29743
                     /locus_tag="ACG8M1_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0422095.1"
                     /translation="MGLVLLSPSVSAESSISMYRMYNPNSGEHLYTRSVGERDNLKRY
                     GWHYEGVAWQAPTSGSPVYRLYNRYNGEHFYTVDAGERDKISHTGWTYEGVAFYSYNG
                     ANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNSAPNPTPAPAPS
                     NEKLLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPRANDNNPYHGYS
                     GEWRYNVSGTYQGIMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGNPVVTWITYN
                     YASPQFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINASTYERAFNVTGMA
                     VAVR"
     gene            29918..30148
                     /locus_tag="ACG8M1_001374"
     CDS             29918..30148
                     /locus_tag="ACG8M1_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422096.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            30184..30408
                     /locus_tag="ACG8M1_001375"
     CDS             30184..30408
                     /locus_tag="ACG8M1_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422097.1"
                     /translation="MIDISLIEKLLFSNKYTAKELATRWQISESAIKAYRQNKGSVGW
                     RDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            30625..31500
                     /locus_tag="ACG8M1_001376"
     CDS             30625..31500
                     /locus_tag="ACG8M1_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422098.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKEE
                     ITKMKPVIKILDNKE"
     gene            31510..32304
                     /locus_tag="ACG8M1_001377"
     CDS             31510..32304
                     /locus_tag="ACG8M1_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422099.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNIL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            32603..33451
                     /locus_tag="ACG8M1_001378"
     CDS             32603..33451
                     /locus_tag="ACG8M1_001378"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422100.1"
                     /translation="MIEYDFNEAYSRIMRNYPLPSNTYLKAKYNTDQAILRAINRPKV
                     RPYENLKTYMLFLVNFEGTAKEGTYANPKSQSMFADYGENPKTANEPIWLSEIELTLI
                     LDYYDIKEMEVLDSHTFLTKKGLLKEYFERIEPLKTDPDTLKLYKNLRTKVFGAIGQK
                     SLREGETNTFDKYSMYNRAYSSMVAGVFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRS
                     EVPEFEELYKLGVVKKKVHTISKEEVEKALEFKNKGFENKGSFGNSKDEVKGVVIDDD
                     FEFDFD"
     gene            33484..33804
                     /locus_tag="ACG8M1_001379"
     CDS             33484..33804
                     /locus_tag="ACG8M1_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422101.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            34059..34952
                     /locus_tag="ACG8M1_001380"
     CDS             34059..34952
                     /locus_tag="ACG8M1_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422102.1"
                     /translation="MRTHYIYLEDKIIDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EDEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHEELSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNAYI
                     ARLKRFIDKYKENSDKFSKDK"
     gene            34972..36606
                     /locus_tag="ACG8M1_001381"
     CDS             34972..36606
                     /locus_tag="ACG8M1_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422103.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNNGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMSLTIKRIYDLLYVYKH"
     gene            36635..37804
                     /locus_tag="ACG8M1_001382"
     CDS             36635..37804
                     /locus_tag="ACG8M1_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422104.1"
                     /translation="MTKKIEVYVDGSQEERDSFFDFFWKNSREYVKALNLVYKQLMFE
                     ELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKLDKAKAELSKLRNEKNKEAR
                     EILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASKDFGNDFIGIVTGQRTPRIY
                     KNRSKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLGSKPRKARDVASVLQHIMDG
                     DYKLNQSNLIFDGRKLFFNLTISFEKRYNELEFKEGNELIVNFADLCSGECLVNNKSV
                     MSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLKEQLVNKGKRYGIEVRS"
BASE COUNT        14344 a         5222 c         7699 g        10798 t
ORIGIN      
        1 tccttaataa acaaaatttg aaaaaagagt aatgactatt tagtcatcac tctttttttg
       61 ttcggaaatt gaaatatgtg gagcttgtat tggtttagtt aggattgctt ggctatatgg
      121 agctagttct ttatcaaaac catcaaaata ggttttcagt agcgatttaa ctgatcgctc
      181 atcttgtttg acttggataa tttcagcatc caaatcggtt gtgaggtcag gagcttttga
      241 tgcgattacc tgattttttt tatcttccaa ctctcttagg ctgtttaaca agtggtaaaa
      301 agaatcattt tgactgttca ttccaacgtg agatgcaatt ttaacagaag tttcatccgt
      361 attgtcatca agtatttcat caaaagtact cattggaata tcaagtagta acgaggatga
      421 ttcctttact gattttttct ttacagcatt tttaattttt tcatcttttt tgctctttgt
      481 ttgagatgtt tttggagcta gtttaggtag attacctgtt ttatcagtca ttaattagct
      541 tttcctttct acttatttat gttattataa tatcataata acataaaaat gtacactttt
      601 gggggcgcag ttattgaaaa aatcgaagaa aacgttcggc acgttgctta tcgcagtgat
      661 gcagataatc gggattacag cgagtttaat cacgataaat ccgcaagtga cacatgctga
      721 tggaatagct acttatgatg cacagttcaa ctgttctact gaaggctcgc aagggtctag
      781 tggatcagga aaagatagtg atggaaatga aacagggagt ggtgctgtat caggtgatgt
      841 agcaaaaaat attgatgata tttacaaatt catgaatggg gaatatgggc tatcaggtgc
      901 tactatcgca ggtattctag gtaactggaa acaagaatca ggtaatgatc ctcgaacggt
      961 agaaggttat tacggtgatg gacagagaga agttgacttt atcaaacaat tcactgatgg
     1021 tctgatgggt attggctatg gtcaatggac agcaggtcgc catactgcat tagtaaactg
     1081 ggcgaagaaa aactttggtg gcgcttggtg gacgacagaa gcgcaattgg attttatgtt
     1141 caaaggcgat ggtggatttg ttgctatatt aaaagattat gctttaaacg cttctgatga
     1201 tgttgtggca aatgccgtag cgtttcataa gaattgggaa atttcagcag attccgaatc
     1261 agctgtagtg gctgtacgtg gtggaaatgc aaaagaaatt tgggaataca tgaaaagcaa
     1321 aggcatggac ggagctaaag atgtaagcaa aatcaataaa attgccggag gaacaagtac
     1381 cggtggtgga tcaaataatt catcaagctc agcatcagga acagtagaag atgcctgtgc
     1441 aactacagat gatgctaatt ctggttctgg atcaatgggt aaagaaggaa aaattaacgg
     1501 taaaaaaggt caagtaatag cgaatatgac ttatgaagaa gctttgaaaa aatatgggaa
     1561 agcgatcacg ctaccaaaat tcaaagaacc agattggtca acttcacctt ttaacggaat
     1621 atatcaaggt cagtgtacag agttgacgtg ggcttatatg agccaattat acgatgggaa
     1681 tcaaccgact actggaaatg gtggctatgt atgggaaagc tacaaatcgg caggagcgaa
     1741 aataacgaac aaaccaatcg taggttatgg gtttagtgct tcggatggat ggttatgggc
     1801 tgttggcgat gcagggcata ctggtgtagt tatagcggtg tttgaagatg ggtcatttct
     1861 atgtgctaac tttaatgttc caccaaccca agctccaaca aggggagttt cggtaacttt
     1921 gattgatgga gtggacggat cagataatgt gcatttcttt agcggtgtag gaaaagctaa
     1981 atttgaaatc gaaaaataaa ttggaatgaa ggacgatata gatgaatagt aaagtgaaag
     2041 atacaattat catttctttg ctttctggta tgttattagc actgcttgtt ggaatcctat
     2101 tcttcaataa gcagaatcag gacatagaag ctgaaaaaca cagtgtgcat attgaagata
     2161 agctgacatt ctttaaagag gttaaaccaa atgaggtgga tggattacgg aaagatttag
     2221 aaaatgatat tcaagaaatg ttgaatggat cagttcaaaa taagtttgca gatcaatcag
     2281 gtgaagaatt tttgagaaaa ctatttattg tcacaggtaa accaccaatt actgataaga
     2341 gtagtgataa agaaaaaatc gagtactata agccttttac ttttaagcta acaaactttg
     2401 gaattaagac atctagtagt gggttgtatg aagtattgac cgattttgaa gttcaataca
     2461 atggaaaaaa agtgtatgat accacattaa ccatcacact aaataatgat aagaaagtga
     2521 ctgggggtgc tttttatgca aaatcatgaa atcactactg ctaaaaaggc gattggaata
     2581 ctttccataa ttgtgatcct ttgttgtgtg gtactatttc aaaagaaaaa tgcttatgat
     2641 aataatgtca aagaattgga agaccttaaa agtaaacaaa tcgaagtagt caagaataac
     2701 cagaaagtga aagctatgca ggaagcccaa tacaaagaat tggggaatgc tgaaatcaag
     2761 gaacaaagta ggaaattctt taatttattt tacaactgga attcatggga aaaatatacg
     2821 aagaatatga aggaaataca aaaagaattt cctcagatag taaagtctag tcctgttgat
     2881 atttctggca cgatggtagg cactggtaat agtccaatat ctagctatac tgctgattac
     2941 tatacaacaa atcaaaaagg taaaatggtt gaattgatta cacagacaag aaatactcca
     3001 acaacagcaa caacaacaat ttggcgtgga gtaacaagca taggagaaaa tcaattgttt
     3061 tacttggagg atttagatag ctatgtaaga gcagagtaaa ataaaaaaag agctaacggt
     3121 accaacgtta gctctttgtg ctgacgatga taacaaaacc taccgaaaaa ggattgtttc
     3181 atcacaaaca caaacagaaa agaattgata aaaaacccga acctcagaat ttttattaat
     3241 caattcattt agattataat aaattgagct gaacattaca atacgtatat gttgtaaaac
     3301 gtaaaaaaag tcaaaagtaa atactttctt aaaaagtcaa ataaaactat taaagacaat
     3361 atatatggtt tatttgacat aagaaaatgg tctagatgat aattgtaata tagaattgta
     3421 gacttaaata aagcataaaa taccttctat gataaggtat agctcttaat tttaagcagt
     3481 tttagatata agattgaaag taaagtgggg gagaataata atggcagatc gtaaattaga
     3541 aaagttatta gaagaaacgt ggaatccaaa agaatttagt gaatttttta tggagaattt
     3601 tgaaactgac ttagcagtga ttgttaaaga tgctcttaga gagcaagggt atcctgaaac
     3661 tgcaaactat ataaacatta attttacttt gtatactgaa aataaaggaa cttgggattt
     3721 ttgggctact ttagcaaata aggagttaag tgataaatca gacacaggaa ttcgtaactt
     3781 ttttgaatca aacagagatg attatatgta tgctaacaat caaaataaat tgaactttag
     3841 agtagagttt gatgaaacac ctgaagaatt tatagaaaga caaccgccta aagaaaatgt
     3901 agcaaaggta ttggaagatc gttggaattc agatgaaata gtttcaacaa ttagcgaact
     3961 aggcggacaa tatgaaccgc tagtagaagc ggttagagaa gagctaagac tgaataagtt
     4021 tcctgatgtt caaaatattg atgtttctca aattgaaata aacgtcaaga tcacgaataa
     4081 acttgattat ggtagttggg cagatatagc attagaaaaa tacatctact caacgttaaa
     4141 agagtttatc gaaaatagaa tggatatcat gtatctacag catccacagt atttaaactt
     4201 tggtgttgaa atagctacac ctcttgaaga atggaaaatg gagcaagggc ttgactagcc
     4261 tttgctccat ttttttattt tacaaatgaa tacagttcgt cgtttttacc aagaatgatt
     4321 gtttgcccaa ctttgagatt gtcaggtgat ccttcagcgg tttgtaagga gaacgttcca
     4381 ttgaacttat cggataccgt tataggtagc tttaattctg atccttcctc atctttgaga
     4441 attgctgttt ttcgttcatc aaaataaaca gtctttatta aataattttt cgtagtgatc
     4501 tcagcagatt tgtctttttt tgtagtagta ccagtttctt tagaattaga ggtattttct
     4561 acgactattc catctttggc atttgagctt gtgtttattt gattgaatat tttcagcgac
     4621 aagataccgc taagaatagt caatatagaa ataagtgtaa ttaatactga taatttcctt
     4681 tttttgttca tttttcttaa cttccttttt tgttttgatt agttagatat tccttatcta
     4741 acaagcattt ttaggctatt aaatgaagat aaaccccaaa aaaatattgc aattatgaca
     4801 gtgcaatggt actattatta tacaataaat tttgcgaaag gggtaggtct aaatcgcaaa
     4861 caaaaagaaa ttgaacctag acaaatacaa cttgtatacc gcaagggaag caagtttgat
     4921 tttgggtaaa ggtagaaatt atgttacaaa cataattaac tattatccaa atcgtttgcc
     4981 taaaggttcg ttcaagaaag tgggtgacaa aacctatatt ataacggaag aaggaataga
     5041 agcattgcga tcacaaacag aaaataaaaa caaaaagaag gaatgaatat gaagaaaaat
     5101 tcgcttggta tggttttatt tgcatcagct gtacttgcgg ggttatcagt accagtaacc
     5161 tcacatgctg atgaatggac tgcaaacaca ccggatcaaa tccaaattac aacaggacaa
     5221 tcaagttatg cgttcaaaaa aggagatact atttggtcaa ctgtagagaa gcttaaaagc
     5281 ttaggttaca agactactgt tgctgagttt gccgaattga acaatgttga tttggcaaaa
     5341 ggagaacaac ggactatccc aattggacga actttcaaca tcagtaaaga tacattaaca
     5401 gttaaggaag cagatggcga agtagttagt caaactgttc aaaaggataa acctgatcct
     5461 gttgaaaata cggagcaaga gaacaaaaaa tccgagacta caaaagaatc ggaaccaaca
     5521 gcaaacactt ctgataagac agaaacaagt gcttcaagtg ttgatggagc aagttcatct
     5581 aatacaaata attctacaag tgagaaagaa gcatcacagg gaacaagtga aagtagcact
     5641 acggaagctg atactggaac atcaacaaat aactcacaat caacatcaaa tgatgcaaat
     5701 gaatcaacca gtacatcttc tagtgatcaa tcacaaacag gttcgagtga tgaaactgac
     5761 agttctactt caccaagtaa acccgaacaa ccaactaatg ttgtgctagg cgttccattt
     5821 attagtcaag gtaacacaat gctttgcgaa ggaacatctt tgctagaagc gttacattat
     5881 aaaggtgttg caacaaatca agatttaatg acttttgtta aatcaatgcc actatctcct
     5941 gataataatc caaataatgg tttttctggt gaatggagac acaatgtgga tggaacttat
     6001 caaggtatga atccggctcc tgtagtttca tggggtgttg ctaatggcgg aaatgttgta
     6061 gatatttctg gttcatcggt acaaggatta aaagatgaga ttgtaaatgg aaatcctgta
     6121 gtagcatggg taacttatgc ctttgaacct gctcaacata aatcaatgtt ttggggcgat
     6181 gctatttgga atcgacatgt agtagccgtt gatggattta aagacggttt ttaccatgtt
     6241 gtcgatcctg tgtttggggc aagttggatt aatgcaggat catttgaaac agcatataac
     6301 gtatctcaat tagcggtttc ggtacgttaa taaaagagat cgtttatata ctaagtagtt
     6361 aagtatagtc tttatttgcc cttacttaac tacttagaaa acttgttgct catggtgggt
     6421 agaactaaaa ggggtgatgc tatgaataat agagcgttga aacatcttgc tttcaacgaa
     6481 aaaagtgatt aataggtgtg gtgattttaa cttaggaatg ggcgcgaagg tcattaccac
     6541 accgacatat cgtggctcat tttcttcgcc taactggtat aaagaaggag taacgagaga
     6601 tgaagcatga aaaaacgata attttaaaat caaaaataat ttattgtttt gcgactttag
     6661 taatggtgtt atctacgctt ataatgcctt tttcagcaat aagagctgaa gcagatgtca
     6721 caaaaccgac aagtgcaaaa tttacagaaa ctggcgtaaa aacagacggt tatattaggg
     6781 ttaatatgcc gaatcatcca aatgaatgga tgatttcaag tcaatttaaa gattctcatg
     6841 gaaatattgg atattgtatg gattcagaat tgccatcccc aacaggaagt ggagccggaa
     6901 gcttgaagta caagggagct ggcagtgatg agttctatcg tatgtttaaa ggtggttttc
     6961 catcaaaaac agcaaaggaa ctgggtgcag gaaatgatac agaagcatgg tatgcaacac
     7021 aattagtttc atgggtttta gccggaaact ttaaagtttc acagattgta tggtcacatc
     7081 caaaccatac cgccgcagaa acagctcgtg taaaaaaagc atttgaaaaa atttatgact
     7141 atgctaagaa tggaaaagat acgcccaaca ctgagttttc tatcacagct tctaagacag
     7201 ctgacgaagg aaaatatcac actttcacat ataaaacagc atcaaataag actggtaatg
     7261 cgaagctcac ttttacatca gcaaaacctg ctggtatgaa gatttatgat gcagatggta
     7321 aagaaattac taacaacact gtaaaattaa attcaagttt tactattaaa gtacctgtga
     7381 ctacaccaag tggtactttg tcatttaaag gtactgctaa tgttagcacg accaatcctt
     7441 ttacttttga tggacgaggt gtgtatcaag atgccgtagt tatgatcact acttcagaaa
     7501 caaaggactc taaatctttg agtgctaaat ggacaagagc tgttggtcag gtaacagtta
     7561 agaaagttga tcaagatgga aatgctttaa aaggagcgga gttcactcta actgacaata
     7621 acaatgctaa atctgttaag acaaccggag atgatgggtt agctacgttt gatttgcaac
     7681 aaggcttaac atacagctta gaagaaacaa aagttcctga aggttatcaa ggttcattta
     7741 aaaaggatgg tattactgtt aataccgatg gacaagaatt tagttacact gctacgaaca
     7801 caattaaaaa aggtaaaata aaagttaaaa aggttgacca agatggaaaa ccattagcta
     7861 atgctgaatt taccttgacg gatgattcat cccaaacaca agcagaaaaa acagatgaaa
     7921 acggacttgc aagcttcgat attgtagcaa acaagaccta cagccttgaa gagaccggag
     7981 taccaactgg ttatacaggc gcattcaagc aagaaggaat taccgttaaa gatgatggac
     8041 aaacttttga atatacagct acaaacactt tgaaaaaagg tgtagtaaaa gttcataaag
     8101 tcgatcaaga tggaaaacct ttggcaaatg cagagttcac tttaaccgat gaaaaaggtg
     8161 caacacaagt agaaaaaaca gatgaaaatg gacttgcaag cttcaatatt gtagcaaaca
     8221 agacgtatag tctagaagaa accggagtac cagtaggtta cacaggtgca tttaagcaag
     8281 agggtatcag tgttaaagac gatgggcaaa cttttgaata tacagctaca aataatttga
     8341 aaaaaggtgt agtaaaagtt cataaagtcg atcaagatgg aaaaccttta gcagatgcag
     8401 aattcacctt aacggatgaa aaaggtgtaa aagaagttaa aaagacagat gcaactggtc
     8461 tggctacgtt caacattatt gcgaacaaaa cttacaactt agaagaaaca aaagtaccaa
     8521 caggttacac aggcgcattc aaacaagaag gaattaccgt caaagatgat ggacaagtct
     8581 ttgaatatac agctaaaaac actttgaaaa aaggtgtgat caaagttcat aaagtcgatg
     8641 atcaagggaa agcattagca aacgcagaat tcactttgac ggacgacaaa ggtgtaaaag
     8701 ttgtacaaaa aacggacaga aatggcttgg caacatttaa tattgttgcc aacaaaacgt
     8761 acaaaatcga agaaacacaa aaccctaatg gttatacagg gaaatggtct aaagaaggca
     8821 tcaccgttgc tgacgatgga caaacctttg aatatacagt aattaatcac cttgtacctg
     8881 aaacagtaag aacaggcgga atcggtacat cagccttcct tcttgtattt ctaattgcag
     8941 gattgagtat ggtgctactg tattatcgag aacagcacaa agcaaaataa aaaagtgtta
     9001 atggaaaaga agtaaatatg aaaaaagaag gctgacgtat gaaatcaaaa aaaatttttt
     9061 caaatttaat gctatttggt actttgctag gagtgggatt gggcgcaagc tcaatctctt
     9121 ctagccttgg actagggggg caagtagcat atgcacaaca aaactataat tatcaaggaa
     9181 ctggaacgat tcatatccat aaagtaacaa atactaatgg ggatgggaac cctgtctcag
     9241 atattgataa caaagggaaa gaaatagctt taccaaatgg tgtaaaacct cttgaaggcg
     9301 ttgagttctc ttatgtgaaa cttactaaag atgaagctaa atccttggga tggacggata
     9361 gtgatactac aaaaggtcaa catattgatg atgctaaagc acgattatta ctaaacaaaa
     9421 aatacagtga agtaagtaga atgaagactg attcacaagg gaatatagac atacctatac
     9481 aagtaaatac agacgattta acagataact tgtatttgat tgttgaaaca ggaacagtca
     9541 aaggtgtagt tgaagaagcg tatcctatga ttgttaacgt acctgaacta aacggatcag
     9601 atgatcaata ctttaattat gatgtacatg tctatcctaa aaactatttc caattaaact
     9661 cagcagagct tgataaaaaa gacgaagatg gaaaggctct tgccggaact gtttttgaat
     9721 tgcgaaaaga tgatggatct gatcaggttg ttggaactta taaaacagac agcacaggta
     9781 aattaactgt ggatggtttg gaattaggtg actattattt cctagaaacc gatttgggaa
     9841 cagatgctaa tagaacaacc tatttactag atggtaaaaa attcaaattt agcgttaaac
     9901 gtggggagac tgctaaagta gttcttgatg ttaccaacta caaacgacct gtaattacta
     9961 aggtaattga taaagaaacc gttgatactg gcgaagatgt tcaatataca ttgaaaccat
    10021 caattcctgg taatattggt aattacgaaa aatatgttgt caaagatgtt ctaggtgcag
    10081 agttaactta tgattcatca gaagtgatcg aaggaatgac tttagatact gattacagta
    10141 tcgaacgtga cggacaaacg acaaactatg tctttactga atcaggtatg gataagcttc
    10201 agaaacaatt tgatgcaggg gatcgcttct ttacaatttt gatgaacgct catactaata
    10261 gtaaagctaa aatggataca ccacttaaga atgatgtttc aacgatctac aacaatggat
    10321 atgaacccga agacgaaaca ccagttgatc acgcttatac aatcattggt gatcaccaat
    10381 tcattaaaac agatggagat acaagcaaag cattgagtgg agcaaaattt gtagtgaaga
    10441 acaaaattga tccgaataaa gttacttacc taaaacaaga tccaacaacg aaagctgtta
    10501 cttggattgc agataaatct aaagctactg aattcgtttc cggatcagac ggtaagttcc
    10561 aaattgaagg tttgcaatat acctatgatg tagattttga taaacaaggt aatccaacaa
    10621 tcacagataa aaaaatcaat gattatgctc ttgaagaagt tgttgctcct tcaggatata
    10681 caccaactag aaacgatgtt ccatttgtgg tatcgaatga tgatgcttct agcgaagtaa
    10741 cagacatcaa gaaccttaaa acacctgaaa cagttcgtac aggtggaatt ggaacagtag
    10801 tatttctagt ggttgcaggt gtggcaggaa cagggctata tgttgtctac aaacgagaac
    10861 aacacaaagc ttaatgaaat aaaattccct agagtgtttt tggctctagg gtttcttttt
    10921 aaaaagtgtg tgaaaagtag gtatgagcat gaaaaagaag aatatcaagt tgatcatctt
    10981 aaaaattggg atgttgctat gtttaggagt aggtctatat cctgtaatta ctcaggctta
    11041 tacctactac caaactcaac aaacactaaa ctcctataag gaaaaatatg atgaagcttc
    11101 tgaaaaggag aatgaagaag tcttcaagag atattcagaa gttaatagga aacgaaaaga
    11161 cacagaacaa acctcagtca cgattcctga agataataac aatattccgt caaatggaaa
    11221 tcttcagaag gataaattag gtgaattagt gggtgaaatt cttataccaa agattaatgt
    11281 ggatttgcca atttatgatg gtgtaaacga tttccaacta tcagcaggag caggaatatt
    11341 aaccggaact gattatccaa ctggtgggat tggaaaccat tctgttatat cagctcattc
    11401 aggcattcct aataaaaaat attttacaga tttagagttg ctcaaacttg gtgataaatt
    11461 ttttattgat atttcaggga aaaaacttgc ttatcaagta gatcggataa aaacaattct
    11521 accaaccgaa tttgaggatt tgcttcctgt ggcaggaaaa gattatgtaa cacttatgac
    11581 atgtacacct gttggagata attctcatag gttactcgtt agaggggtta gcatacctta
    11641 ccaaaaaagt attgttgaga aagaaaagaa gaaagaagat ttaaaggtaa aggcgcagat
    11701 gaactggtat cctatcgtag ttgtaggggt tttattaata atagctgtga tagtcattat
    11761 taaaaaaata gtagcaaaga gacgaggaat gaaaaatgaa gaataaaata ctactttttt
    11821 tgactcttat ttgcactttg gttttaacaa tttatcctgc aagtcagctc tatcatcaat
    11881 tcaaaacaaa agagaatgtg gcggaaatcc aagagaaaat tgagaaaaaa caaactcctt
    11941 caaaagagga agtggcaaaa aaagtcgaac aaataaaatc gaacagcggt aaccaaggat
    12001 tagacaatac tcagaaaaca gataaaggag tagacaatac tcaggaaaca gacggtggat
    12061 catttgatat tcgtgaagct gaaggaaagg tcaatccata cacaggagat gttttttcaa
    12121 aaaatcaaac gaaagatttt gaaccatcta cctattcagg agcggttggt tatgtctata
    12181 ttccaaaaat aaatgtgcta gagcttttgt ttctaggcgc ttcacaggag catttatata
    12241 gaggtgtggc acaaatgagt gctactagtc tacctttatc aggtaaaggt catcaaacag
    12301 taatagcagg tcatcgtggc ggttatacgt caccacaatt tctttatgtt gatcaattag
    12361 tagccggaga ccacatttat atagattatc ttggtgaaaa agcagtttat acggttttcc
    12421 gaacagacgt tattagaaat tacggtcaga attcaacact gactgatatt cctgatttag
    12481 atatgttaac actttatact tgtcatccat atcctcagaa ctacgatcgt ttattagtta
    12541 gaagtctaag agatgaaaaa gcaaaataca tcacgccaca agtaacagtt ggcaataccg
    12601 catacgctga tgccattgat agtgaatccg tttcagataa gccagaaact gttacatctt
    12661 ctaatgattt atttgaggat gttgatcgtg ccaacaagga attagatgga aataatgatc
    12721 ttaatattcc ggaacaaggt agcgtagaga tgcaagacag aacgtttgct gaaaaggcaa
    12781 gttcaatatt tacaggaatt accaataaac atcagaaaat gcttttagtc atttggactg
    12841 tattaggagc attagcaagt ctaaaggttc ttattctttt aatcaaagag tttagaaaag
    12901 cataatgaag attataaaaa ttgatagagt acagtaaaaa gggattgata ctattattga
    12961 tctctttttt attttgaata gagctagatt cacttttaaa taaaatcaaa actgatctta
    13021 attccaaaga aaaagtcaag aaaaaaatac aacaaatttt tttatcagaa tatttatcag
    13081 aatattatta gaaaagataa actcaaaagc ttaatttaat agggttattg gttgtattta
    13141 gaaataatgt atggaaaagc tataaagcaa tagataagat gtagaaaatc ttatttgtga
    13201 atgaaaaaca agtcatcgta aaatattaat aggaggtgta gtaatggtgg aaatatcaaa
    13261 aacagcttta gactcattag ctaaactatt tagtagcagg tttgatggtg cagaatttgt
    13321 tgaatatcta agccaaaacg aaagtggaaa aactctgatc gaaacactga aaaaagacta
    13381 tttgaatgaa aatgactttc cgacatggac gaatattgaa gatgctacat gggatgtagt
    13441 gtgtacgata tattctcctt gggtaacgat tgctgatttt gttttagata aaattgaagg
    13501 ggatacatac cctgatgcca aatctcttgc tacaagtgac tttaaaacgt tctatggtta
    13561 tctaatgggt ctaataggca atggaataga tttgaaagtt acgccaaaac aaacacctga
    13621 agaaattgaa aaagaaaaag gagaggttca aatggcttat gcagatgaca gagaaaaagt
    13681 aaaattattg gaaggtaaat tatctgaaga agaacttgga aaaatggtgc aagaaatcaa
    13741 tgaagacagc aactattttc ctgaattgaa ggtatatcaa aacgacgaag atttctttaa
    13801 tgaaatgttt agtaatagtc catgggaagc agtgagtaaa acaaatttag gagaatggaa
    13861 ctttcaagat gatctagttg catttagcaa tgatgggtat ttacgatcat attcagaaag
    13921 tgagtataga gctgaattaa aaacgtatga aacggatatt ctgatgagct atttaaatct
    13981 attagagagt ggtcagggag agttaagaga taaagttgaa gaactattaa aagaagagct
    14041 atagggatta tttcaacata aacacaagca gaaaactacc aaacaaaacg taccatgcaa
    14101 aaagccggtt taaccggctt tttgctctat tatgagagga gatcaaacca tgagtgcaac
    14161 aaccgatatg gctttagaag cagtaataaa agataataca ggaaatgtcg aaaatgtaga
    14221 agactttagc gatattgcaa tcaatctttc agcatggatt tcagctgtag gagaagaaaa
    14281 tatcgaattt gagatcaaga atatggatga cttaaaagca aaatttcctt ttatcgcatc
    14341 gaaactaagt caatttgccg aggagaaatc gtggaatgaa ttagttagtt tttccgaaaa
    14401 aatttatgat attacgcaag aagatgagtg tgtttcatgg gaaatgaata atcaatacaa
    14461 gaaaattgat gctttcgtca aatcacgtat agaaggaaca gcttttgagt ttgaaggtat
    14521 agataccgca gataattggt taaataaaga atcctttatt aaaagtatag cggatgatct
    14581 tgaaaaacaa tggtctaagg aagactatgc agagtaccta aaaacagaaa gagatacaga
    14641 ggtgaaagaa aaactcactg aggtatgttt ggatgaacat attgatccca atatcgtaaa
    14701 acaagaagac tatgaagtgg ttattgataa agttcctact gattttgagg aagttgtaaa
    14761 gtatatagtt gaagaagcat tatcgcaata ctcttcagat gaggaagtgg acgaagaaac
    14821 tgttcgtacc agagtttggc aactggtttt tgatgacaaa gattataaat atttgagtga
    14881 tcaaaactcg gttaattgga gtgtacgatt attaattgat caaaatgata ttgaataaaa
    14941 tagagctgaa aagctctatt cagactgtag acaaactcct aaattgggag tgttgtttgc
    15001 agtttttttg ttttatactc attgtataaa ctattctggg agtgattcta atgatgagaa
    15061 aacaatcgat tgaaggtaga aatcaatttg ctatgttaac aattgatgat cttgtaccta
    15121 aagatcactt agttcgaaag attgatgctg cgattcagtt tgatttcatt tatcccattg
    15181 tagaatctac gtattcgacc catggtcgtc ccagtattga tccagtggtc ttaattaaat
    15241 tagtatttat ccaatattta tttggtatcc gttcgatgag acagactatt aaagacgttg
    15301 aaacaaatgt tgcttatcgt tggtttttag gttattcatt cgaggatcct atcccgcatt
    15361 tctctacttt tggtaaaaac tatgttcgaa gattcagaga aacaacttta tttgaagaca
    15421 ttttctctca tattctagaa caagctgtaa aagctggctt cgttacggaa gacaaccttt
    15481 atattgattc tactcatatt aaggcaaatg ccaataaaca taagttcaca aaagaaatga
    15541 cctacggtca agctaaagct tatcaagatg aattagaaga tgaaataaat aaagaacgta
    15601 ttgctgtagg aaaacgtcct tttacatggg acacagaaag tgagttgagt cttcaaaaaa
    15661 taagtcattc agatccagaa agtggttact atgttaaagg tgaacgagaa aaacaatttg
    15721 cttattccgc gcatacttcc tgtgaagata atggttttat cttatctaca ttaatcacac
    15781 caggaaatgt acatgacagc caagtcgcaa tcgatctggt caaacagtcg aaaagagctt
    15841 ttccaaatat aaagcgtgtt gtcgctgatg caggatataa gacgcctaaa tttgttcatt
    15901 ttctgtcaca cttgaaactc tacccgattc ttccatatac tgtacctcat ggagtaaaag
    15961 gaatgtttcg taaaaaagac tttgtttatg atgcctattt tgactgctat ttatgtccca
    16021 ataatcaacc gttgttattt tcaactatca ctcgtgatgg ttatcgaacc tataaatcaa
    16081 atccaaaatt ctgtaggagt tgtccattac ttaaaaactg tactttgagt acaaaacatc
    16141 aaaaaatagt aactcgacat gtttgggcgg atcttatgga tgaacttgaa caccaacgcc
    16201 atacggcgtt gaatagagaa atttataaaa agagaaaaca aaccattgaa cgaatatttg
    16261 cagatgcaaa agaaaagcat ggtatgcgtt ggacgaaata tcgaggtctc gaaaaagtcg
    16321 ccacgcacac gatgcttacg tttgctgcca tgaatttaaa aaaactagcc acatggctat
    16381 ggaaagcaaa aaagcctatg gctttttatt taaaatttct acaaagacta acaaaaagga
    16441 gttggcaatt aagccactcc tttttgtcta cagtctgaat agagctgaaa agctctattt
    16501 tttttgataa aaaaactagc tattttttta aaaataattt ggttcaaaat ttattttttt
    16561 aacttgataa ttttttgcca tcctttttta aattggctat atatcaaggt ttatagtggg
    16621 gataaataaa aatacatttg acaaaattta caatatagtt tattatatat ttatcttatt
    16681 atgataacac aataaaagga atgatggtat gaaaaagaag gagtttagtc gatcgttgtt
    16741 aggaatttta gttttagttg cggttggtct tagtggcaag ggttactttc agaataacag
    16801 cactcaggaa catgattttc agatcaaaag tagtgttcag gtaggtaata aagcagacag
    16861 tgaatcaaaa gaatttttag ggatacgtta tgatccaaac aaatatccaa ataatatcgt
    16921 aaacattaat gatgggaaat atacactgac aaaagaagac catgaagcat tatcagaaaa
    16981 aggcagtcaa accttttggg taaattatgc agatttagat caacttggaa gagcaggaga
    17041 tgttgaagcg ttgatcacct atgatgctgt aaattctcac tcatctaaaa atgtggaacg
    17101 tccatctttc aaaagttctg tccatattgc aggagaatac aaggatggag tatttgatca
    17161 agagagagat acttgggtcg gcaaagattc aaacaatgaa atcactcagc tagaaggata
    17221 taaaggttat ctctataaca aaagtcattc attagcatgg tcgctaggag gagatatgga
    17281 ggtacacaat ttaacacttg gaacgagagc gcaaaatgtt gggaaaaatg atcagaatgg
    17341 agggatggct tactcagaaa cgattgtacg tgatgcaatc tataaaaata agaatgaaaa
    17401 ggtattgtat aaagttgatc caatttataa agggaatgaa ttggttcctc gtggttctca
    17461 tgtcgaagct ttctcagtta acgataatgg aaaaacggta aaccttaatg tttatgtatt
    17521 taacaatcaa aaaggaatca acatcaacta tcaaaatggt acttgggtaa gagattagaa
    17581 attgagaagg tgaagaattg gaaacaataa gcatcaatgg attagataaa tcagttgcaa
    17641 atcgaataaa aaaaggaaat ggctactatc ttctgaagaa gggtaaatat tcagttgcta
    17701 gagagttaga aacaatgagt atcgtgtatg tagctaagaa tcattttgac gtagaacagg
    17761 ctatttttga tccagattct gaaataggga aatgtgttga attatcagag aaaactgtta
    17821 gtacaaaagg ggcgatgatc attgagagag aaatgttaga cgaaatcaga gtaatcattc
    17881 ctaaagatac gcagatgtgt gaggacagca taagtgacga tgaaccaaaa tcagaaagaa
    17941 aataaggaga tattcagatg agcgaaaaat ccattgaatt aaaggaatat aagcgaagcg
    18001 atggagaaaa atattatcct gtagccagtt tttctaaatc agtatatctg gttggacgtg
    18061 cattggtagt tggtgcaatt ggcatatata ttttgcattg ggtaacaaag gttgtacaac
    18121 tgcttgtaga taccttagta agtattcttg tctcgttaaa tgatgttaac ggaacagatg
    18181 atttaggatt aaaagaaatg tttaaagagt tactcaatgc gttttttccc aattatttaa
    18241 gttattcata taatgtacaa agcttttttg caaagctaca cttggtagac atctctattt
    18301 tagtattaga agcaggaacg gtattctttg ttggatattt ggttactttg atgttcaggc
    18361 atcactatgg agaacaaaga ccattttttg atgatatgga aagtagaagg ttgaaaagag
    18421 aagctctaga agctatggat gtgaagtatg atccaaacaa gattatagga gatgaaacga
    18481 acaacaaaaa aagaaaacga aacaaaacgc aattagaatc cgatgtgcta tcaacgctta
    18541 aaaatatcaa aatttctgtt catacaagac gtgatctaag tgtcaatgaa gatattcgag
    18601 aatatatcgt aaaaatcccg caaccaaaag ggaagaaagt tagagaaaca gttttacgac
    18661 aaattcaaga tttagggtcg atcctgacaa gagcaacaag cggacgagcc aaatttggtg
    18721 aaaaagaaga tgaagtttca ggcgattatt tcattttccg agcatcagta aatattgaaa
    18781 gagaacgtaa ggaaagagta agtaccaaaa acaaagaaac ggaaagagca acatcttcaa
    18841 tcgcagtttc aaattcacaa ttttcttttc caatcaatct ctttgccgat aattccaaaa
    18901 atatccaaaa ccaaaccgaa aaagctagaa aatatgccga aactcaaaag caatctttag
    18961 aactttatct atcttctgct gacgtacctg caagtctaac agatatgcac gttgggaata
    19021 catctattga atatttgttt actttatctc gtaccagaaa aattcaacta agctcaatga
    19081 aagaagaaat tgaaacttac ttgcatatat caggtgtaat cgtgcggatc aacgcagggc
    19141 gtattcaaat tactttacca ttaggagaaa atgatcgtat tccaattgat gtaccatcaa
    19201 tgatcaatag cgtgttttaa aagacatcac aaatagaaac agaaaataca aactaccagt
    19261 tcacaaacag aaaagtaccg agaaaagtga ggaatagaaa tggctatgaa attattagag
    19321 aaagtcaaaa agagagccga aaaagctgaa tctattttgc tagataaaga acctaatata
    19381 aagcttaatg gaaaattcag tgtcaatatg ttgaacacaa aggctaaaga cccgacagat
    19441 gctatttttg gaattaagcc tgatggcaca attgctcatt tttgcatcag cgaaatgcca
    19501 cacatgttgg ttgcaggaac gacaggatca gggaaatcag tattactgaa tgaaattctt
    19561 gttacagcaa tgtgtcactc aacgcctgat gaattaaaaa taggaattgt agacccaaaa
    19621 agggttgaat ttggaagata caaaaaattg ccgttcatgt tggctgatcc aattacagat
    19681 atggatgaag cttatgattt ttttgaatat cttgtgatct tgatgcatga acgttacaaa
    19741 ctgatggaaa aagcagggtt acaaaacatc acgctatata acgaatatgc cgaaaaaaat
    19801 ggattagata gatttcccta tgtgatctta ttagttgatg aatattcaca gttggttgga
    19861 acacataaag aagtagaagg tttgattgtt caattaggac aaatggcaag ggcagcaggt
    19921 attcatgtta tcttagctac acaatctcct cgatcaacag ttgtcactgg tattatcaaa
    19981 gccaattttc cgtcacgtgt ttgccttatg gtagcaagtg atttagaaag taggatcgta
    20041 ttagatgaag gcggtggaga aagcctaagt ccaaagggag atatgattat taagctcgtt
    20101 aatggaagta tggttagagc gcagggagct tacatcagta acaaagaaat tgaaacaatt
    20161 ttcaatcacc ttagaaatac tatgccagaa ccagaatatg ttgattaccg agcaatcgta
    20221 gctgaatctc gtggtgaggg tggagaagac gaggattttg gtggaattgg taaagctcct
    20281 gtaagaaaat ctgctaaaag aaatttgaac acacctttag caaattcatc atctaaagag
    20341 ccatcaattg aaaagaagag tacgtttgct ctaaaacttg aaaaaaacaa agaagaaaaa
    20401 gaaaaacaag gagctaaaac actagaaaaa cttcaagccg aaaaattaga aaaagtttta
    20461 aaagcattag ataaagctga ttctgaaccg caaacctcaa acaacacgaa taatgaacag
    20521 ccgatttcat ctaaaactaa accgaaaact actgatccga aagtttcagt aaacgtgacc
    20581 atcacaaccg ataagtctga gaagaaacaa gtaaacggaa cgacttcacc tatcatgcaa
    20641 aaaatgttga aagccaaaaa acaggtgcat aaatgatcat tgtcagttct tttttgaggt
    20701 ggcttacgcc atataaatat acagatgaag tagttgtgaa acgaacgaag aaaagagata
    20761 aaaaagcggt actaactcct aaacagatgc ttgatcatgg cattttaggg gtgaaggttt
    20821 tagaagtgaa taaaccgttt gaatcaaata gtgcaagaga aaagttgctt ggagctgaag
    20881 ccgatgtcgc atatttttac catgacaaaa gcaagcatca aatagctatt aaattcaatc
    20941 caaaatcggc atggcggtat caagcaagag atgacttgaa acgtaggaaa cttagaccaa
    21001 tgctctatcc agaaggaaaa gaagcatttg atagaaccca catcgttccc attggttttc
    21061 atggtacaga atcagataac cgcctattag taggttggaa cagcaatcaa aatagagttc
    21121 agatcaataa atttgagaag aaagtaagga aattcaacga tcgaaaaacg atcctatggt
    21181 ttgcagatat ttgtaaacag ccggatggaa cagcaaagtg ggaagcggtg atatttgacg
    21241 aaaatggtaa aaaagtaatg tctgaaacat ggcatgataa agctaaattt gtttggcagt
    21301 agcagtagag gtgaaaaaga ttgctagaac tttttgaagc aaatagaaca ggctttaatc
    21361 aaaaattaga agtgggagaa actatagaat ataaagataa aaactatatt attatcggaa
    21421 tctataacac gagaattaac agaataggtg atccacgtat aaccagtgac ttggtttgtc
    21481 aatctgttaa ctattcacct gatctgacaa gcaggtataa gaaatacgtg ttattagaat
    21541 atagacacaa gattactgat gaaattggtg taaacaacac acgaaacata tttaagatcg
    21601 gaacagtgat tccttatagt aacaacgaag aaaaaatatt ttatcagatt tacggaatag
    21661 aaaagtttga atatgaacat gtcgatctgc tagtgacgta ccaaatgcgt ttaatagaac
    21721 cttggtcaca ggcagaaatt gataaagcag taaaattgaa ccgattatca aaatttaacg
    21781 tattaggaaa tgccttttaa aaatcgcaat acacaaacag aaaaatacca aaaaattagc
    21841 aatgaacgta ggtaagaaca tgacaataaa taataataac cctaaaaaat ataatgctct
    21901 tgtccaatgc tatatcgaaa acaaaattac aatgcaagaa gtcgctgatg aattaggcaa
    21961 atcaaagagc ctagtatcac acgattttaa gcacaatgtt tttccgaacc cgattgagct
    22021 gaggaaaaaa tttcaaaaga gagtttatca agaaataggt aagtggattg atgaagggaa
    22081 tgcaattgac cctttaattg aaaaatatcc ttttttaaaa agcaaaaata aaattcaaag
    22141 gttaattcgt caaggcgata ttcaagctaa agaacctgtt ttgacaacca atgatttggc
    22201 taaaataaat cttcataaac aaattattga agactttgaa aaaaatcttt caacaactga
    22261 aattttaaaa aaatacaata ttccgagagg aaagctaaca tcgactcttt ttagagaata
    22321 tggagaatcg gcagttacta aagcaaagga agtagcgaat gagagaaaaa aacaaaaata
    22381 gtagtcgata cctagtagcg actgtagttt ttgtttgtgt attgattttc ctgtttgatt
    22441 ttttgcagat tggaaaaagc ataattggaa atacattgag tgcaaaggaa atggttgctt
    22501 taggtggttt gtatgaagga cacttgttcc cgaatatatt catttctatc gtttctcata
    22561 ttaacttgta ccatttaatt tctaatttat tgttcttagt agttcttgaa gaagcactga
    22621 atgatcagta tgagtggtta acattattga tcgttttaat catatcagga tttctaggaa
    22681 gcttagttcc ttttctgcta cacagcaaca tcgtaagtat ggggcttagt ggaggtattt
    22741 ttggatggat tgctttattt gcgattgcat acatccgttt tgatagcaag aaacatttat
    22801 tactaagtgt ttttgtatta ttgataatcg gcattttact ggtatctact tttgaatcag
    22861 gcgagacaaa cgtcttgtca catgtaatcg gatttgtctg tgggatgatc ttgggattta
    22921 ttctaaagaa cgtttcattg atcaaacaaa agaattaaaa gggagtgcta aaaatgccaa
    22981 aaaaaaaaga aaagaaaatt ccagtgtttt tgtctgtctc agaaatgtta tcacttcaaa
    23041 tactgttaag aaaaaagatt gaaacaatag acgaagaagt tagaaataaa agggctatgt
    23101 acgaacaacg tgaagcgcta agagaacgaa tccactattt tgatgatata cacactaaaa
    23161 tctatgaagc acgtacaaat cacgaagacg aaagcaaatt aggattagct caacaacgaa
    23221 tatttgaatg gctgaatacg aatactgagc aagaaccgtt aagagcaatt agtaatcttt
    23281 ttgaatttgg aacgaagcat tggtttaacg ctgtagaaaa ggatgctgac ttacaagaag
    23341 cgttcgatac actaagcgag gatagcaaat ccatgcgaga cttattgatc acttatctaa
    23401 atgagcatga atttgaacag acgaaagtta aaaagaaaaa taaaaaatag aaagttgtga
    23461 tgtatcatgc tgtttacctt attaggttat ttatgtttag ttcttgcttt ttttggagca
    23521 attgctatat ttgtcggtca gtttcaagca aataatccga taatgcgtaa cataggcatt
    23581 ggaattgtta tcatatcctt gattgtattt ggtgccacaa agatttttgg gagtaatgat
    23641 cagcagtttg gtatttctgg agttgataat agttatgctc cagattcatt gggaagagta
    23701 gtgatagatg gaacgtttga gaatgtaacg agctacaaaa atgtttcatt gacagtgaaa
    23761 gaagatgaca agaaagcatc agatgacgtt ctcgctacga tcaagccgtc tcaatcacag
    23821 tttgaagtgt tttatacagt caaagagaat aaccctgtac gcaagctaac attagttttt
    23881 aacgttgacg gagaagaata ctataaagat gtaaaaatca ataaagcatc aacgaaaaag
    23941 attgtcgaat cagcgaaaaa agaagtagct acagaagaaa gtacaactga atcaagttct
    24001 actgtcgaag ttgaactacc agataaaatt gattttgatc ctgaaaaagt caaatcgttt
    24061 gaatctgttt ctggttctat ggcagatcgg tttaacactg aagttttcaa agctatcaaa
    24121 actgttaaat tggatactga aaagcaaagg attaatgtta ccttattcaa tgcagttgaa
    24181 tcaatggatc aggataaaaa agttacggtt gcaagagaac tagggaaaag agtaattggg
    24241 ttgtatcgag gtacggcaaa accagattca gacggttcag atttgccagt tcacgtagtt
    24301 tatgaagacg gtaaagtttt tggagactct acagcaaatg aagcactaac gattaaatta
    24361 gctaaatagc cggaaaatta taataaacaa gtggtgtcac accaccatcg cataggtgtg
    24421 acaccttgga gatgattact gatggtagta aataaagaaa aagtaagaaa gtatgttact
    24481 ttaaaaatag cttctgttga atatttagaa aagcgagcta aagaagaaga aaaaacaaga
    24541 ggtaagaagg taacagtttc agagttgtta gaagaattaa ttgagagtga ccaaacaata
    24601 agacgtgcat ttaccaatag gtctgttaaa agttagggtg atactatctt taatttcaac
    24661 caaatttcta atatatgatg aatagtttcc ttgtacaaaa tatctaatta agagataaaa
    24721 gttaggagga ttcattcaaa atgattatcc aaaagtttga ctggaaaatg aaattaggaa
    24781 ttagtcttgt aatattggga tttattattt ttttggggat aaaagcacaa aaaaatcaat
    24841 ctacttttga aactatgtct tctcaaatta ttgaggaatg ttccaaaatt tattattgtg
    24901 agaacaaaac tgaagaatct aatggctttt attatatcga tcaaccacat gatgttgtta
    24961 taaaaatgga gtcacatgaa gtaaacgaat ggattcaaag aagtactaat gtatcaaaaa
    25021 agttagaaag atattctcaa acgtttttaa gtaaagtcat tttttcaaat tgcaaaaatg
    25081 aagaaacgtc tcaaagagta gctagttctt tagaaaattt aaaattttct gtttcaaaaa
    25141 aagagaaatt tgtagattta cgaaaataaa ctatcgaaag tagtatgatt atgatcttaa
    25201 aatatcatct taagagaaga attacgattg tttataggat ttacaaaatg aataagtttg
    25261 aagagtgatt tggtcgcaga ctagatcact ctttttctgt aaaaaaactt tacacttatt
    25321 tttgagtgtg ttaagatttt ttatatagag tgacggtttc ttgtcagagt gaatgataac
    25381 catcaatatt ggaggaataa taagtggaaa acaataatga tattagatat tttagcattg
    25441 gggaaagagt tacaacagta agtgaattat caaaggatta tagagataaa gaaggaacga
    25501 ttatttctct taaaaagaat cgaagaggtg tttggcaata tgttgttgat ttaggggatg
    25561 gcgttacagt tgagtgtaaa gatagtcaac tgatcagaaa tgatggcagt cattccattg
    25621 aaaaagcaat tcttgtattc ccaaaagtat caagcaagat tatgaatgac tggttgcttg
    25681 gaaaatttgg tgagtacaat aaaaaagaaa tcgcagaagt gatcggcaaa tcttatccaa
    25741 cagtattagg gtatctaaaa aagataacga acaaagaagc gaaagttgag gatgttttaa
    25801 cagtaagaga acttcagtca ttaatcgaat atcggaataa acaaataaca aatcctgagt
    25861 accttaaaaa agaagatggt ctattgaaac aattggaaca ggtaaataaa atccggaaaa
    25921 tgcaaaaggt agctccttta agcctagata actttaaaaa aatctatttg aaagagatcg
    25981 aaaaagacta atgtggagtg tcactttacc gtttcaacct gtatctgcac caagaccaag
    26041 tgcaagaagg aatgttgctg atgcaactaa tgacgtagca gagaaaagga tttcaaccta
    26101 ttatgataaa aagtatctcg attatttgaa aaaaataaaa agctttatcg aagatcaagg
    26161 tttgttagat gatgaatttt actcgatcgt aaatgatccg atgggtgcaa ttatggaagt
    26221 ggacttttac tatcagatac caaaaagcta taaaaaagtc tataacatta tgaagacgac
    26281 agcgccagat ttagataatt tagtaaaaag tgctatggat ggtattttca acatctcagc
    26341 tatacgagat agccatatca cagggttaat tgcttttaaa tacaatgtgg caaacgaagg
    26401 aaaaacagtt gtgaggatca agcgatattc agaatttgag tgggatactt ctgaaggatt
    26461 gaacggagat atttgggaag ccacatttga tttcaaacca gtagcaacgc caagaccaaa
    26521 gtctaaattt agaggaaatg ggattatcac ttactatcca aaagagtata acgactattt
    26581 ggaaaatatc aagaatacgc ttaaagagaa agatttggta aatgatcaac tgaaaaaggt
    26641 aatgaatgct cctatggggg ttatagctca gatagattat ttttaccaag tgagaaaaga
    26701 taagaaaaag cttgattcac tgatgcgtac ttcacagccg gatattgata acttagtcaa
    26761 aggaacattg gacggaattt ttaacaagga aattggcatc aaagatagca gggtggtagg
    26821 tttaatagct tttaaataca atacttttga aaagtcgaaa acaaacgtgc gactacagga
    26881 gatgggctga tgaataataa cgaaaaaatt cttcatgtac ttgatagctt tgaaacaatt
    26941 caagaggaac taaagaaata tcgagatgtt ttggaacaaa gatatgattt tgtcaatcag
    27001 caaaagagta atcacatgga tttcattctc aatatgaatg acttgaagaa gaaattagtt
    27061 gaacgaaaag aacaagaaaa gttgatcaaa gcttactttg aactcggtga aaaagaagtt
    27121 aaaaaggcaa tggaactgaa tgaagatcgc agggttttag atcagctgtt agaacaatta
    27181 ttggtgatgt ttcaaaaagg acgaatagat gaggatttaa ttgaagaagg gttgagaaag
    27241 tatcctgcaa actcaggtat cggaatagtg ctgaaagcga ttgatgaaga agaaattgaa
    27301 gatttcatac cggcagagga ttttgaatcg gcaatggaat atataaaata ttacagccaa
    27361 gggatcactg cttttagaga gtttgatcct gaagatgtta ttcatgactt gaacaaccta
    27421 aaagaatggt gtgaaggtta tgaagttgat gattccggtt tggactactt gatcagtatt
    27481 atggaaatcg aagaagagat gccggataag cctgatccaa cagatatttt agaattaatc
    27541 catgatgcta gaaatccaat tgcatacatt tctagaggat atactgtatt ggaatactat
    27601 aagccttata tatcagcgat gaaccattta agacgtgtat taagggaaaa acgtgaatac
    27661 cgctcagtgt taaatgcatc gaatagatta gaaaaagctg tttcagagct agatgcttat
    27721 tatcgtgaac attacctgca agcaggtggt atgccaagaa atacgaaagc aaatatcagt
    27781 aggtatataa aagaagctga gtaggcggag ttagcccata aaatggcaaa aggtaacctg
    27841 aaaggggcgt tttgaatgaa aagggatgtt tttgaattgt acgtattaga acgtctagaa
    27901 gacggcatga tggcacaaga gataattgat gaaatcgatg atatgatcag cagatttggt
    27961 caattggaat tgaatgatgg aaacaaaaat tcggtagtgc tacaacaatt ttggttaaat
    28021 aatttttcgt ataaggattt tatcaaagaa aaggcaaata gattgtactg actaaattca
    28081 cgaggatcag tgatgagagc ttattgctaa gagcagttag gctctttttt gtttgtgtta
    28141 aattatttta ttttacaata cacatttata cacaaaaaat gttgacggat agtacacaaa
    28201 tgtggtagga tatatttgta agcaagttag attaacaagt taaaggaagg aagagcagtt
    28261 atgaaaaaag aagaactaat agatatgttt caaattgttg aacgagcaaa taatatggga
    28321 attatgtttt ttgatcgtat ttctttaaag atggatttaa gcgttgccca ccaagaattt
    28381 aatctacgat taaaagcttt attgatttct gatgatgtta atttcgctca tgatgttgta
    28441 ggtatacaga accatataga tagagaaaac aaacgtatgg gtgatggatt cttaccaaga
    28501 tattcaagtt tatgatttgg cgaaagattc aagagtatgt gtcattattg ataggtactc
    28561 ttgaattaga aaggaggaat gaatttaaga caacaacgat tatgatctta aaacaatcgt
    28621 ttatgtaatt ggcaatctta cgaataattt tcatgcaata atgacaataa aaaatgaaaa
    28681 ggggtaaaat caaatgaaaa aatttttagt aggaattcta ttcacaatgg ggctagtgct
    28741 attatcacct tcagtttcag cagaaagctc tatttccatg tatcgtatgt ataatcccaa
    28801 tagcggagag catctataca ctagaagcgt tggagaaaga gacaatctga aacgttatgg
    28861 atggcattac gaaggtgtcg cgtggcaagc tccaacaagt ggttccccag tttatcgctt
    28921 gtacaacaga tataacggtg aacattttta caccgttgat gccggagaaa gagataagat
    28981 ttcgcacaca ggatggacgt acgaaggtgt tgcgttctat tcttacaacg gagcaaatag
    29041 agttcctgtg acacgcttgt acaacaaata cgtgaattgg caccattaca cgttagatca
    29101 aaatgaaaag aacgtaatta gtaaacaagg ttggaagatt gaaggtacgg gttggtatgc
    29161 aatgccaaac agcgcaccaa atcctacacc tgcacctgct ccaagtaatg agaaattgct
    29221 aaatgttcct gtcatttggc aaggtaatac gatgttgtgt gaaggtgctt ccctgttaga
    29281 gggattgcac tacaaaggag tagcgacaaa tcaaaactta accagttttg taaactatat
    29341 gccaagagct aatgacaata atccttatca tggctattct ggcgaatggc gctacaatgt
    29401 gagtgggacg taccaaggca ttatgcctga tccagtagtt aaatgggcaa aaaatgttgg
    29461 tggtaatgcc gttaatatca ctggttcagg aacgaatggg atcaagaatg aaattcgcaa
    29521 tggtaatccg gttgtaactt ggattactta taactatgct tcacctcaat tcaaacaaat
    29581 gccttgggga cgtgcagtct ggaatggaca tgtggttctc gtggatggct tcaaaaatgg
    29641 tgcataccat gttgttgacc ctgtatttgg cgcaaaatgg atcaatgcaa gcacgtatga
    29701 gagagcattt aatgtgactg gaatggcggt tgctgtacgt taattgatag aattaataaa
    29761 taaatgaaat aagagcttaa ttactgaaat ggtaaatggg ctcttatttt ttagaaaaaa
    29821 ctttttttgt aatacgaatc tataacaaaa aacgttgaat atagtacaca aaagtggtat
    29881 attaaaaccg tagagattat gcgaagaggt gattttgatg aaccaaagaa gaagaaaaag
    29941 gctagaagaa ataagcgagc gactatccga gttaaaggat gagttagaag taattcaaga
    30001 agaagaggaa gagtacaaag aaaatatacc tgaaaatcta cagggatcag aaagatatga
    30061 aaaagcagaa gaatccgttg atcaacttga agaagctgtt gatggtttat ccgacatatt
    30121 agaattgatt gaagatatag ctagctagag atgattaatg aagatttcag gagtgagcaa
    30181 aaaatgattg atatttcact gatagagaag ctactttttt caaataagta cacagccaaa
    30241 gagctggcta caagatggca aatatccgaa tcagctatta aagcctatcg tcaaaataag
    30301 ggaagcgtag gatggcgtga ttggaaagga atcagcattg gaaaagcaga agacataatg
    30361 aaacgtgaag gatttcaagc tgacaatgat tctaaaaaag ttgaatagtt taatagtcgc
    30421 caagaaaagt accagggcga ggggaaaggt agattacaaa ggaaaacact tttaaataaa
    30481 cttcgcaaaa gcatcaggtt atgagtggct agggctatac gaatgtgatg aaaacaaagg
    30541 gctttaatgt caaagaaaac gcaatagggg gggaataaaa tttttaaaaa agatatttat
    30601 gtttggttta atgggaaaaa atatatgact actaacaaaa ggtggtcaga gctagtacaa
    30661 aatacagtta aaaaagtcat gccagatgga tatcatttca actatataca atgctcacaa
    30721 acaactgaaa gtatttattt ttcaatatta aatgagaata gactctatta tttcagggta
    30781 agttcacacc ataggaaaaa gagagaagat aatgttacga catttttatc gggaaaatac
    30841 aatggcttca aagagttaag tgaagcaatt ggtgagtatc taaaaagtaa tagatttgtc
    30901 agaatttctg acaaacatat attgatcttg ttactttatt tgaataatag cttcaaatta
    30961 ttttggagag acgacacttt ctactatatt gagaacggca tggatattta ttctggtatc
    31021 aacggcatat taaaacatta tattaaggcg ttacttcgat atggggttct ttatcaagaa
    31081 gatttaagta accaaattaa gattagtaat tctggaaagt cattactggc aaaatataaa
    31141 aaattgcttt ctcctatcta caaaggaata gatatggaag ctgtaaattc tgaaacttta
    31201 tttaatttag ttgttgatga aaagtttgcg aatgaatttt ttaaaagtaa aaaaattgaa
    31261 agactaaata acctgtttcc tgaaaatgca ataaaagctt atgtagataa taataaatca
    31321 cgattataca actggtttat tcccaaacgg ttgcgaggaa aaatcaaaat tggcgatcaa
    31381 gtgaaagtaa ttaatctaaa tcatactaag atcgttaccg taacggagtt gtatatagct
    31441 gaaaaagaag agattacaaa aatgaaacca gttattaaaa tactagataa caaagagtga
    31501 gtggaatata tggtagcaaa aaagaatact ctaaaagaag cttctgaaaa atatcaagat
    31561 atgaaaagac gaggattaat cccaaaggac aaaaaaggta tatggagaga atttgttaag
    31621 gaagtcagta gtgatcgaag tggcggtgac tttgttggac gatatacagc aaaaggttat
    31681 agcaggcgct taaggatcac tgttgaatat ggaacgaatg aatcagctac agagctgaag
    31741 caaaggtact tagatacacg aagagaagct tcaaaaaaat atgatgattt caagagcaga
    31801 ggtctaattc ctaagaagaa aaaggggatt tggcgtgagt ttttcaaaga agaagatagc
    31861 aatcggaata agggagactt cattggacga tacacagcaa aaggctacac taagaattta
    31921 gggatcaagg ttgaatacgg aactggtgaa agttcatggg aattgaggaa tcgctattta
    31981 aatatattgt tagagaaata taaagcagaa ttattggagt tgttcgatgt taatgatttt
    32041 atcgagatgg ctgaaaagta tggtcatgaa gaaggtttta tgatcaatga cattatggtt
    32101 attgataatt ttacggattt attagcactt gcgaaaaaag caagggattt aagagaaacg
    32161 cagatgtatc tattcagaaa taaaaacgga agaaaccgga gaactgaatc gagtgagatt
    32221 gaagattact acgatgcctt tacacacgat ctgggagcct ttgtagacga gataagtggt
    32281 gtaatgaaca aatatagggt ctagaataaa aaagccggag atgagcagat aaatgggaaa
    32341 caatagcata tacacacctg aaatgcagaa taaaattaaa agacttgtcg gattagggtg
    32401 gatgacaaga ggaaaattag attcttttag tacgatcaaa tatcttttga tggacattta
    32461 ccgtcagaac aagcaaacag gaatacattt tttgggctat gataagccgg aagatgcacc
    32521 tttctttgtt ccaagttcag cctatagagc cagtacctcc ggtagcatgt acaacttgga
    32581 tttgttcgag gaaggagcaa agatgatcga atatgatttc aacgaagcct attcgaggat
    32641 catgagaaat tatcctttgc cgtcaaacac ttatttgaaa gcaaaatata atacagatca
    32701 agctattttg agagcgataa atagaccaaa agtaagaccg tatgaaaatt taaaaacgta
    32761 tatgttattt ttggttaatt ttgaaggaac agccaaagaa ggaacatatg ctaatccaaa
    32821 atcacagtcg atgtttgcgg attatggtga aaatcccaaa acagctaatg agcctatttg
    32881 gttatcggag attgagctaa cacttatcct tgattattat gatattaaag agatggaagt
    32941 actagatagc cacacatttt tgacgaaaaa aggattactc aaagaatatt ttgaaagaat
    33001 cgagccatta aaaactgatc ctgatacgtt gaagctttat aaaaatctta gaacgaaagt
    33061 atttggtgct atcggacaaa aatcattaag agaaggagaa acaaatacct tcgataaata
    33121 cagtatgtat aatcgagcgt attcctccat ggtagcaggc gtatttagag atcgtatggt
    33181 tagatatgaa cagaaatacg ttcatagcgc atatgggcta ttaaaaattc gtactgatgg
    33241 attgtatttc agatccgaag taccagagtt tgaagagctg tataaacttg gagtagttaa
    33301 gaaaaaagtt catacaatat ccaaagaaga agtcgaaaaa gctttagaat ttaaaaacaa
    33361 aggatttgaa aataagggct cctttgggaa ctctaaagat gaagttaagg gtgttgtgat
    33421 agacgatgat ttcgagtttg attttgacta aatactcttt ggaaaagatg gtaggaggta
    33481 aatatgaaga agaaaattgt ggaaggaaat gtaggtgtta ttattctaaa agattcaact
    33541 gactatgcta aatcaatggc actaaaagac gaaaaagttg cacgcatgga taaagattta
    33601 gttgaatttc tgatggatga tacagaaaga ttaaaagggg atcagttttt gagtttaatg
    33661 aaagacaaag gcttaaacac atatggttta tttgattata agaaattagc tatagagtgg
    33721 gtaaaagaag gagaaatatt ttttattgaa gaatgggaag gtactgagaa cttagttctt
    33781 catcagtatc ttttgaaagc ttaatctaag taaaacagtt ctgactagtt atgcttgtca
    33841 gaatttcaaa ggatgttttc cataaccatc atcattcaaa aataaaggat ttgaaaataa
    33901 gggttccttt gggaaatcta aagatgaagt taagggtgtt gtgatagacg atgatttcaa
    33961 gtttgatttt gactagattt ttttgcaagg tttaagagta aacaaggtaa gaactaagat
    34021 catgaagatt gagagtaaag aagatagagg acgaatgtat gagaacacac tatatttatt
    34081 tagaagataa aattatagat gaaattccgg caaaaagtcg agaacaagct agaaaattat
    34141 ttattgaaaa atacaaagag atcaatggag atagtgaagt tccaaaagtg gtcgtaacag
    34201 ttagaaaaag gcaaacaaaa aagagaagta cgtttcatgt cagccctgat atatataatc
    34261 ttatagagcg acatagaagt gaagataata tttctatctc tcaatatatt gctacagtta
    34321 ttgatgaatt gatttcagga aagtatgact atgcttttga ttttgaggat gaaaaggatt
    34381 acaaaagtgt tgctgtcttt caatctgatt ttgagaagct aaaaaactat gctggcagga
    34441 gaaatgttaa ttttgcaaga ctactagaag agttctactc cgaagagttg ggagtaggaa
    34501 atgaatacaa gagagaaact tatgcgaaat tgtctcataa gttatcccaa gcgcttaaag
    34561 aagtgacaga agttaaagcg gaactagatg ctaaacttga agaagtgaaa aaatatcaaa
    34621 cagagaggaa gaacaacatg aagaatcaag tggaatttga cgaacagaaa gaatttgaaa
    34681 aagcaagaaa acgctataac aaaattatga atgaacttag ctatgaacac ttaacagttc
    34741 atgaagaatt gagtgagggt acagaaaaat atacgatcgc agatatggtt aatgaagtgg
    34801 aaactctttt agcttctttc tttgaaaatg gtcacgtaaa cgatgaatgg cgaaaagaag
    34861 aacctaaaag ggttaacgct tatattgctc gattaaaaag gtttattgat aaatataagg
    34921 agaatagtga caaattttct aaagataaat aaggagagag tgtgattaca tttgccagaa
    34981 atcgaaggaa tattttcgcc aaaaataggt aaaaaacagt tagatttcag cagttttccg
    35041 agcgtaaata gagattataa tctaggtgat gaggtacaga tactaaatat tgatttcaaa
    35101 gaactagact tcgctgttgc tgtttccaac aaacccaagg cattggaacg agtgaaaaaa
    35161 atataccaag agaatgatca aaatatcaaa aatatgatca aaaagtatag acgagataat
    35221 tcaaaagttg aagacgtttt attcaacggt acggcaaaac atgatttgaa tgtttatatg
    35281 gcattaggag tggctttgta ctgtaattca attaatcaga cagatatttt ggttaatatc
    35341 gtgaggaata gctatcaaaa aatattaaaa ataagtagcg aaacaaaccc ttattatgca
    35401 atgaaatatc ttggggataa tttattaaat gataaaaaat tgatgcacaa cactgaagag
    35461 ctgttatcta atttggctgc gattaacttt ctattcaaaa caggttctga agattatttt
    35521 atagataacg tactaaaagg tgcttacgga acagcatttt atccgcttta caatatgaaa
    35581 cagcataaag ccgaacaaaa ggataacaaa cttgaaatta aaaagatgaa agaactatta
    35641 ggtataggat ttgtaaagcc caattcaaaa gtcactattg cttcgttagc aactactaac
    35701 aataatggga aaatagtaaa tgggtttgac gattcagata tagatatatt gtcaaaatca
    35761 tatttttctt tgtatggaga ttttgcagat ttgatgggta ttgatagtta cttagtcaat
    35821 aattttgaga tcaagggtag cgagctgaat gatattgtgt atttcgtttt aatctctcta
    35881 tatgcaattg atcagaatac cgagtaccga caaattgact atttgctagt tttttatagt
    35941 ttgttatatc agttcgtttt aactcggttg tttaaaaatg ctaaggaaga attgatcctg
    36001 aattctgatt atgaaatagc aaaacaaatt gcaagtatta gaaaagaaaa caaatctgaa
    36061 gtaatcaaat taagaaaaga attaagtatt gcgagtaaag aaaacggtcg gttagaatct
    36121 ttagtcaaat cggcaaaaaa agaagaggaa cttttgaagc aagagattaa agaattaaaa
    36181 ggaatcagaa aagaacttga acagctgagg tttgaaaata aagtattaaa gcaattgcag
    36241 gagcaagaac atagacaatc attaaatggt aaaactgaag agccttcact gtctgaaatg
    36301 atagcttatc taaaacataa aaacattctt ttagtgggag gacatgtaaa ttttcaaaat
    36361 aaattaactg aactattacc aaatattaaa atgtttgatg taagcgaaaa taatggaaag
    36421 atacttaaaa atttgaatac gtgtgatgcg atttttctat atacagatta cttgaatcat
    36481 ggtctatatt atcgtgttat gagtgaaatt tctaataaag ataagatatt ttatttagat
    36541 aatcatgtga atatgagctt aacaattaaa cgtatttatg atcttttata tgtttataaa
    36601 cattaatgag gtgttaaaat tgacaacaat aactatgaca aaaaaaatag aagtatatgt
    36661 tgatggatca caagaagaaa gggattcctt ttttgatttt ttttggaaaa atagtagaga
    36721 atatgtaaaa gcgttgaatc tggtatataa acagctaatg tttgaagagt tgataaaaga
    36781 tgcaattaaa gaaatggatc aaggttatgc tgagagagaa gaaagtattc aaaatcggat
    36841 tgaaaagtta gcatatactg atccaataga tcaaaaaaaa cttgataaag caaaagctga
    36901 attatctaaa ttgagaaatg aaaaaaataa agaagcgaga gaaatattaa cgcaagcgat
    36961 agggttgaag agtcaaacga gaacacgaga tgtagcaaaa aaattagact ttgactttgg
    37021 agattttgtt gattccgcaa atatgaaagc tagtaaagat tttggcaatg attttatcgg
    37081 aattgtgacc ggacaaagaa cgcctagaat atataaaaat agaagtaaat atggattatt
    37141 accttttaga ggtcgagata ttaaaatcca taaagatgat aagttttata tttatttacc
    37201 taaaggcttt aggtttaaag tgaatttagg tagcaagcca agaaaagcaa gagatgttgc
    37261 ttcagtttta caacacatta tggatggcga ttacaaatta aatcaaagta atcttatttt
    37321 tgatggaaga aaattatttt ttaatctaac aatttctttt gaaaaaagat ataatgaact
    37381 ggagttcaag gaaggtaatg aattgatcgt aaactttgca gatttgtgta gcggtgaatg
    37441 tttagttaat aataaatcgg taatgtcttt tggtgatagc caatatataa gaaacttcaa
    37501 aagtaaaatt ttagcaatga aatcaaaaga acaaagccga ggagtctttt ctaaaggcgg
    37561 tcatggtcga aaaagaaaat tagatcaaga tcgatgggaa gcaataaaga aaagagaaag
    37621 taattttgtt aaaacttata ataatcaatg ttctgcaaaa atcgttaaaa ctgctattcg
    37681 caataaagct caaattattc gtatcattga accagataag gcttatggcg aatgggctta
    37741 ctatcaattg aaagaacaac tagtaaataa aggaaaaaga tatgggatag aagtcagaag
    37801 ttagtaaagt aaacaatcgt tgatttggca acgaaatagt gagggaaaat ccactcactg
    37861 aagggtaaac tccgtcaagt tgtgtgacca gacggaagga cgagcgttgt tggggtttta
    37921 gaaccatata aaacagcatg tttctcaaat tgtgtttgtt tcatttatgt tataataaga
    37981 gttttagagc catataaaac agcatgtttc tcaaatgagt actttaaatt aattgatggc
    38041 gttcctgctt tagaaccata taa
//
LOCUS       DAZKNV010000025        36690 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000025 DAZKNV010000000
VERSION     DAZKNV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.025"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..285
                     /locus_tag="ACG8M1_001383"
     CDS             <1..285
                     /locus_tag="ACG8M1_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0422105.1"
                     /translation="GAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVAD
                     SSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(638..1486)
                     /locus_tag="ACG8M1_001384"
                     /pseudo
     CDS             complement(638..1486)
                     /locus_tag="ACG8M1_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1639..2751
                     /locus_tag="ACG8M1_001385"
     CDS             1639..2751
                     /locus_tag="ACG8M1_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0422106.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2829..3122)
                     /locus_tag="ACG8M1_001386"
     CDS             complement(2829..3122)
                     /locus_tag="ACG8M1_001386"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFQ0422107.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3290..3604
                     /locus_tag="ACG8M1_001387"
     CDS             3290..3604
                     /locus_tag="ACG8M1_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFQ0422108.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3625..5604
                     /locus_tag="ACG8M1_001388"
     CDS             3625..5604
                     /locus_tag="ACG8M1_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0422109.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5617..5943
                     /locus_tag="ACG8M1_001389"
     CDS             5617..5943
                     /locus_tag="ACG8M1_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFQ0422110.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5959..6477
                     /locus_tag="ACG8M1_001390"
     CDS             5959..6477
                     /locus_tag="ACG8M1_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422111.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6477..7829
                     /gene="celB"
                     /locus_tag="ACG8M1_001391"
     CDS             6477..7829
                     /gene="celB"
                     /locus_tag="ACG8M1_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFQ0422112.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7913..9418)
                     /locus_tag="ACG8M1_001392"
     CDS             complement(7913..9418)
                     /locus_tag="ACG8M1_001392"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFQ0422113.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9510..10100)
                     /locus_tag="ACG8M1_001393"
     CDS             complement(9510..10100)
                     /locus_tag="ACG8M1_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0422114.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10279..11925
                     /locus_tag="ACG8M1_001394"
     CDS             10279..11925
                     /locus_tag="ACG8M1_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0422115.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11974..12693
                     /locus_tag="ACG8M1_001395"
     CDS             11974..12693
                     /locus_tag="ACG8M1_001395"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFQ0422116.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13172..14119
                     /locus_tag="ACG8M1_001396"
     CDS             13172..14119
                     /locus_tag="ACG8M1_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422117.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14131..15051
                     /locus_tag="ACG8M1_001397"
     CDS             14131..15051
                     /locus_tag="ACG8M1_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422118.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15092..16549
                     /locus_tag="ACG8M1_001398"
     CDS             15092..16549
                     /locus_tag="ACG8M1_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422119.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16894..17508
                     /locus_tag="ACG8M1_001399"
     CDS             16894..17508
                     /locus_tag="ACG8M1_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0422120.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17501..19225
                     /locus_tag="ACG8M1_001400"
     CDS             17501..19225
                     /locus_tag="ACG8M1_001400"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0422121.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19222..20673
                     /locus_tag="ACG8M1_001401"
     CDS             19222..20673
                     /locus_tag="ACG8M1_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0422122.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21146..23299)
                     /locus_tag="ACG8M1_001402"
     CDS             complement(21146..23299)
                     /locus_tag="ACG8M1_001402"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFQ0422123.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23301..24347)
                     /locus_tag="ACG8M1_001403"
     CDS             complement(23301..24347)
                     /locus_tag="ACG8M1_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0422124.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24497..25786
                     /locus_tag="ACG8M1_001404"
     CDS             24497..25786
                     /locus_tag="ACG8M1_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFQ0422125.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25799..28501
                     /locus_tag="ACG8M1_001405"
     CDS             25799..28501
                     /locus_tag="ACG8M1_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFQ0422126.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28486..29343
                     /locus_tag="ACG8M1_001406"
     CDS             28486..29343
                     /locus_tag="ACG8M1_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0422127.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29414..30271)
                     /locus_tag="ACG8M1_001407"
     CDS             complement(29414..30271)
                     /locus_tag="ACG8M1_001407"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0422128.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30482..32653
                     /locus_tag="ACG8M1_001408"
     CDS             30482..32653
                     /locus_tag="ACG8M1_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFQ0422129.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32721..33062
                     /locus_tag="ACG8M1_001409"
     CDS             32721..33062
                     /locus_tag="ACG8M1_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0422130.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33338..35092)
                     /locus_tag="ACG8M1_001410"
     CDS             complement(33338..35092)
                     /locus_tag="ACG8M1_001410"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422131.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35103..35939)
                     /locus_tag="ACG8M1_001411"
     CDS             complement(35103..35939)
                     /locus_tag="ACG8M1_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0422132.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35941..36624)
                     /locus_tag="ACG8M1_001412"
     CDS             complement(35941..36624)
                     /locus_tag="ACG8M1_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFQ0422133.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11838 a         6442 c         7477 g        10933 t
ORIGIN      
        1 ggagcatatc agctggtaga aactcaagcg ccaacggggt atgaattgga tgcgacacca
       61 gtaactttca agatcgaaaa agaacaagaa gtggcgatct ttttaacaaa agagaataga
      121 aaagttgctg atagctcaga tataagagga aacaatccaa caagcagtgg aaataagcat
      181 cttccaaaaa ctggagaaac catcattagc cagtttatat tgtcaatatt gggtgtgcta
      241 cttgttttca tcagtataaa atttagaaag aaacgaaata tatgagctaa aataaaaaat
      301 tgaataagca tagtttttaa aatcaactag tacccatcaa ttgaatggaa actaccgatt
      361 ttagaagggg tatacaaaca aatattagta tcggagtaga gaaggttgaa cccaaccagt
      421 aaataagtaa agacaatttt gtgctgcgtt gagaagtgaa aaataaacct ttgtagtaat
      481 actagttaat aaaaaatata caaaaacact gcgaaaatca ttcttgagtt tcgcagtgtt
      541 ttttgcctaa tgactcaagt ttattgggta atactttgat tttctttcta caaataatca
      601 gcgatcagtt gtaatttttt ctctagtttt aatggctctt tgtcaataag gagaaaaaca
      661 agtcgggtct tttgtctcgg aaagcttcaa ccaactcgtg aataaaggtt acgcctcctt
      721 gaaaggcgtg gaaaaaccaa gtaatcgatc aatcaccaat ttcgcatttg gtagaacatg
      781 tttggtgagc tgaaagtagg tggcgttcat gtctgtaact aagaattcta tttctttagg
      841 attagtgcag ctaaggaaat agtttgttaa tcgaggaatt ttttgtgtag gtaaattttc
      901 tcgattaatt tttctgtctc gccatccgcg gaaataaaac tcagtttatc ctcaacggaa
      961 acgtgagaac gaaattcaca accctcaaca ctcaagacag aattcttttg gaagactttg
     1021 gtaaatagct tctcaactct ttcaatgtgc gaataacggt tgtcaaagat acctaacaac
     1081 ttttcgaaat aaaaaataac gacacttttt cagtcagtaa agaagtgatt ttatgtctga
     1141 catgatttga aatcgagtgc cttggacgga taaaataact ttgagcgttc caatggcttc
     1201 gacagttttt acaggtatag cgctgctttt ttaggcgtat aaccattggc atatgattat
     1261 attattcaaa gtggacaatg gtttccttct tcttgttttt caccaccatt aatttcctat
     1321 ttccatctac cacagcagaa ccacaatttc tacagacaca tggagcaggg aagagaactg
     1381 cagcaacgat caatgttttt ttcttctgta aggtttcgta agagacctct gtaatcatca
     1441 aatttttgtc tattgatctc agaatttttt tgatagaacc attcataaag catatcgttc
     1501 tctcagttgt ttattttgtg gtgatttaat catacaagaa aacgatatgt ttttttataa
     1561 aaacatgaat aggaaaaata gttgacaaga aaatgacaac gccatatgat gttccatagt
     1621 atttacaacc tgtcatagat gactgtaaaa aataaaagta aaaagaaagg acgacaacag
     1681 gtggattttt atcagtctct acaactagat ccgtttattt taaaacaaaa aatacgagaa
     1741 gcagcttcta aaaaagaaaa gtgcatgtat atttgttcat tgtttttacg atcattattc
     1801 atcgtattgt ttgccatttg ttttatcatt ataattacaa cattatttga atcgaagcat
     1861 aaaccatacg ctgtggtttt attctgtatg ttgatgagta ttcgttttgt tgactttggt
     1921 tataagattt cccattcgat cataggttta gcaatcgtca tgttctcact attagtagca
     1981 ccgtatgtcc agctgatcaa atggtcagtt atgggcatgt tgattcattt tattttacta
     2041 agcagcatat taatggcaac cgctagtgat cccaaaatgg ggaatgcttc tttgtacggc
     2101 ttttcatatc tctttattgt ttattcgtta cctaaagatt cgttgaacaa gaatttcttt
     2161 acacaaacaa gtagcttatt atttttgttt ttttgttggt tttcagttct tctttacaga
     2221 aaacatcgag aaaagaacaa agacaaaagc ttgtttaaag agattttttt gaaaggcatg
     2281 tattcgcagg aaaaaatttg gatgctcatc tatgcatttg gcattagtct tttgatcgtt
     2341 gcaggagagt atgtcccttt tcagcgattg atgtgggcag ggtttgcatt ttcttctatt
     2401 gtatctagct atggattgat gtcgattggt ttcaaagaac gagcagtaga ccgaatcatt
     2461 ggctcattga ttggatgtgt tttatttatt ggtatcagcc aatttattcc ttttaactgg
     2521 gtcggtatat taggtggtct agctttaggt gtttgttcta cctatagata taaaacagtt
     2581 tttaattctt ttggtgcttt ggcaatcact gccagtttat tcggggttcc aggagcagta
     2641 acgatccgca tttttgagaa tatccttggg gtatgtttag gaatcatgta tattggggtg
     2701 actgaaatac ttatccgaaa aataagagaa aaacacggtt tgaatcatta gatgagatcg
     2761 aataaaaaat aaggaaaaag tgaagataca catggatgat aaattgctat cattccatgt
     2821 gtatcttttt acggtaaatc agtgaaacgt tcgactttca tttttaattt atacttttta
     2881 cggagttcgt ttatttgagc catcatttcg gatttgtgat gcttttcgat tgcttcttca
     2941 tctttccaac ggtcgatcag taaaagagat tctggatctt ctagtggaaa gtaatagtca
     3001 tatttctcgt ttccttcttc tgcacgaatc gctttgacaa tgtttctttc gaccatttct
     3061 tctgcaaatt ttctggcttg tccatttgta cttgtataca aaatattcac tgtgatactc
     3121 actaaatccc ctcctgaaaa aattctatca ctagtatatc acggtgccag aaattattat
     3181 tcaagatatg atacacattt tttccgcaat gctacggaaa tatatatttt gaatagaaaa
     3241 cgcttacaag atatgcttgg tttataaaaa taaaaggagt gattgattta tgaaaaaagc
     3301 attgattatt tgtgcggcag gaatgtcatc ctcgatgatg gcctcaaaga caacggattt
     3361 ctttaagcaa aaaagagaag aggtactcgt agatgcagtt tcagctacag aaggcgataa
     3421 tatgattaag aatagtgatt ttgatttatt tctgatcagc ccgcaaacga cgatgttttt
     3481 ggataaattc aaaaaattag gagaatctgt tggaaagcct gttgttagta tccctttcca
     3541 agcgtatgtc ccaatcccta caggcatcca gaagttagca gaggtgatcg aagagaacat
     3601 atgatggaat aggagtggat gataatgaaa cagaaggaaa aattgctgtt gagatatttg
     3661 attgatcaca agaaggagta tgtcaccagt caacgtttag cttctgaatt gttattatct
     3721 gatcggacaa tccgtaatta cttgcagcgg atcaaagagt tagtagaaaa aaacggaggt
     3781 aagatcattg ctaaaccagg ttatggctac caactgcata ttttacaaag actgacattt
     3841 gacttgtttt tgagtcggca agaaatagta cctggatatg ctagagaacc gcaaggattt
     3901 tatgagtccg aagatcgaca aaagtatata ttgaaccaat tgcttttgga agatgccatt
     3961 ctttttatgg atgatttggc agaagagctt tatatcagtc gttccagttt gacaaaggac
     4021 atgcaagaaa tcaaggagcg attgattcca tattcactaa aaatcgtttc taagcatggt
     4081 caagggacat ggatcgaagg ggaagaaaga aatcgacggc attttatcat ggatactttt
     4141 tttggaaacc attatggaaa ttcattgaaa gaatatttag ggcaaagccg ttttttccca
     4201 gacatcagtt ttgaagagct agtcattatc attctcgatg aaacaagaga agctaagtta
     4261 aaagtttcgg attttatcat acagaatctg actttacact tggctttggg gatcaaacgg
     4321 ctccgagaag ggtttgaaat caaggaatta ggcatcgaac aagaagtttc taagcgagta
     4381 gagtatcaag tggcgcagcg gatcgttcaa cgtattgagg taatcgcagg tgtatcgttt
     4441 cccgaagaag aaattgctta tttgacatta catctcatgg ctaagtcgaa tcacaaagaa
     4501 aatcaaaatg atcaggaact atcaaaggaa ttagcgaaag ttctgaaaag attgtctcag
     4561 gaatttcatt tttcattagt agaggatctc cagcttttca atggactact cgatcatttg
     4621 tcaccgatga tgattcgatt gagccgaggt attcgcattg agaacccatt gactgaggag
     4681 ataaagaaag aaaatcccaa agtctttgac gcagtaaaaa ggcatttcag caacatgccg
     4741 gctttgaaaa actataccat caatgaagat gaatgggcct atttggcttt gcatctcatg
     4801 gcggcattgg aaaaagaaag agctgcgcat aaactacatg cattgattat ctgtgcaacg
     4861 ggttacggca gtgcccaact attaaagaat cgcgtagtca gtgaattcgg taaaaatatt
     4921 acagtggtaa gtgtaaaagg ctattatgag atcaatgaaa caactttaaa aggaatcgac
     4981 ctgattattt cttctattga tctttcgaca atgtttttca aaattccagt tttacatgtc
     5041 agtatttttt tgaatgaaga tgatgttcgt aaaatacgaa aggtagttgg agaatctata
     5101 ccctatcatt cctcagatag accgatacca gcattttctc tacagcaaaa aaagcagatt
     5161 tacaccgaac agttgtctga aaaatttttc aagacttata cgtacgaacc gaaaaaggaa
     5221 gaaattcttc atgatttgct gcaaaagctg agcataaatg aagaagaagg atatataaga
     5281 gaaatgcgaa agcagatcca gcaacgtgaa aatatgggac aaatcatatt cagtgataca
     5341 gtggcagtcc cacatcccgc tgttccagtt ggaatcgaaa caaaggtagc cgttgcattg
     5401 attccttctg ggatgcagtg ggatcaatat caagaaattc attttgtttt tttagtttcg
     5461 ccttcttatg tcgaaaatga aggaattacg gtcgtgacta aagcaatcgt taggttagtt
     5521 gaccagctaa aagtacagca ggaaatctta gctgaaccta tttttgagaa tttcagcagt
     5581 aaatttatca aactgatcga ataaggagga aaacagatgg ctgaaaaaat aaacagtgaa
     5641 acactacaag tgacttcttt tgatatcatt ttccatagcg gaaatgcacg gacactgata
     5701 catgaagcat ttcgctcgat gcgtaaagag atgtttgaag aagtagaaga gaagttgcga
     5761 caagcaaatg aagagattct tcatgcgcat cagtcacaaa ctcaacttct gaaagaatat
     5821 gccagcggga caaaaataga aatggaaatt atcatggtcc atgcacaaga tcatctgatg
     5881 acgacgatga cattattgga agttgcacag gaaatgaatt atttgtatca aaaaaataaa
     5941 tagaaaggaa ggatcattgt gcaggataca gtaaaaagga aaatcgaatt agaaaaaaag
     6001 caacttagtt tgaaaaacat gtatttcaat cgttatctaa tcgtacgtta cctgactgcc
     6061 tttttctttt tcatgaacat gcaatggatg attctgcttc tatcagctaa aagtttagga
     6121 agtagtttac cgatgattct gattttagct attttgcctg cagtaggaga acaagtaaag
     6181 ctttatcgaa aacaccaaac gaacgttcca tggacaaagt ggtatttttt gttccagagt
     6241 gtctttaatt tattagtgat tccagtgttg tttacctcag gatttacatt cttgtatcct
     6301 tttatggcaa ataacaatgg aggacagtta tttgttttca ttcttgttgt aagcggtatt
     6361 tttgccagtg catttataca gtatcgttta aagaaaattt cactcaacca agaccaacag
     6421 tatatccgta ttaaacaata tgaaaaagcg ttatatttag gaaaggagaa taactaatgt
     6481 ttgatttttt gcagaaatac ctgatgggac ctatggggaa aattgcgcaa cttaaaatcg
     6541 ttcgggctgt catggcagcg gggatggctt ctattccttt cacgattgta ggctcgatgt
     6601 ttttggtttt aaatattttg ccattaccgt tcccattttt agaaggattt tttaatgcaa
     6661 cttttttcaa agttagtgac ttgtacatga tcgtcaatac aatgacgatg gggattttat
     6721 ctatttactt tgccattgtg tttgcttatg aattaacgtc aattgaacga gatgaacaaa
     6781 aattaaatgt taatccgctc acgggggcat tactatctgt ttttgcattc tttatgtgta
     6841 tccctgaatt gatcatgact gatggtaaaa tcagcttgat tgcttctatc aatgagacag
     6901 aaactgtagt aaatggtatt aggatgggct cttttgtcga acgtttagga acttcaggaa
     6961 tctttacagc tattattatg tcgattattg cggtcgaatt gtattgtatg tgtgtcaaga
     7021 gaaattgggt cataaaaatg ccagatgttg ttccgccagg agtttctcgt tctttcactg
     7081 ctctgatccc aacatttgtc attgcgtttg tggtgatgat catcaatgga ttattagttg
     7141 cactaggaac ggatatcttc aaaatgattg ctatcccatt tgggtttgtt acgcagttga
     7201 cgaatacatg gcttggtgtc atggtgattt atttcttgat ccatgcattg tggatcgtag
     7261 ggatccatgg agcgaatatc atcacttctt tcttgacccc gatcgtatta gctaatatgg
     7321 cagctaacgc acaaggcgca aattatccgt tggcaggaga attcaacaat tcttatgtaa
     7381 ccgttggtgg atcaggtgcg actttaggat tgatcatctt tattgcattc ctcgcgaaat
     7441 ctgatcagct gaaagtgtta ggaaaagcct cacttgtacc aggattattc aatatcaatg
     7501 aaccaatcat tttcgggatg ccaatcgtct acaatcccta tttagcggtt ccgtttttct
     7561 tagctccgat ggcttctgct acactcgctt attttgccat tcggctggaa atcgtcaaac
     7621 cgatgcttgc acagatgccg tggccttcac cagtcgggat cggagcattt gttggtagtg
     7681 gtggtgattg gaaagctgct gtgttagcag tcatttgtgc aatcatcgca ttcattatct
     7741 ggttcccatt tatcaaattc tatgataata aattattaaa tgaagaaaga gaaaaggcag
     7801 cagaattagc tagtgaaaag ttaaaatgat ttctaagaaa aaaggaactg tgacaaaaaa
     7861 tcacagtccc tttttttctt agaaatggga aaccactagt atataaatac cattattctt
     7921 caatcaaccg cttcacgatt gcataatccc cttcataagg ttcatctaca ccattgattt
     7981 tttgataggg atccacgcct tttcccgcaa taacgactga atcttgcgga gcgctttctg
     8041 ctaaagcgcg tcgaatcgct tcaggacgat ccatttcata atgaacgatc aaatctggat
     8101 tagtaattgc ttcattgatt tcttccgcga tttttttcgg atcttcaaat gctgggtcat
     8161 ctgccgtcaa aaaggcgatg tcagctgttt ctgatagcac ttttccaaaa tcatgtcgac
     8221 gggagattgc tttgtttcct gggctgccta atacaacaat tacacggcca tctggatgtt
     8281 catttttggc aaattccagc aatgttttca agcttagata attatgtgca tagtccacat
     8341 agacatgcgc tccattggat tggatcaatt gatccattcg gcctggtaca cgagcttctt
     8401 ttaatccgtc ttgtgcatct tgactggagg cacctgttag tgctgcggca atgatcgcac
     8461 tggctgcatt ttcttggttg aatcctccag ccagcaaaat atcataagca gtatcgcaga
     8521 tagctaagcg atcttcatga gaagataaag taaaaccgtg agtaccttta tctgaacgga
     8581 tcacttgata attgctttct tccgaacgac cataagtgat cgttggaatc tggaatagat
     8641 cggctgtttc cctaagtaaa tcaaaatagt cactttcatg atttaaaaca actgtttttg
     8701 aattcaagat caattgtcgc ttgcaataga aatagtcatc aaatgtcgga tgttcgatcg
     8761 gactgatatg gtcaggcgag atattcaaga agattccgac atctaaagtc aagccgtata
     8821 cgcgttgtgt tttgtaagct tgtgaagaaa cttccatcac tagatgagtc ataccatttt
     8881 caactgcttc tgacatcata cgatataaat ctaatgactc aggcgttgtc aaatgggatt
     8941 tgaaatatgt tttgccatct aacgttgtat tcatagtaga aagcaatgct gtttttttat
     9001 ttgttgtgtg atccaagatt gcttttgtaa agtacgcagc agttgtttta ccttttgttc
     9061 cagtgaatcc gatcactttc aatttatttt gcggatagtc gtaaaaagcc atagcaagaa
     9121 gcgccattgc tttacggata tccgttacga tgattcctac tgctgaattt tcgtatggtt
     9181 gttctgatac ataatattga ataccctgtt cgattgctga atccaaatat tcttctttga
     9241 aattcattcc tttacagaaa aacaaagtag aagcatcagc ttttcttgaa tcataactta
     9301 actgaagaaa ttcagctttt tctggtacat caagatgcca gcctcttgtt gaaacaaatt
     9361 cttttaatag attttctttt aatagtaaat gacggatgtc ttctaaagag aagctcattg
     9421 attgatccct cgctttattc aatttcttgg tttattatag cacactcttt ttaatatatc
     9481 gtttgtttcc gctatgacaa aatccagctt tattcaaatt ttcttgacac aggggacaag
     9541 cggatgagta ttttcataaa caatgaactg actgtaatag ataggagaac gaatagtgtc
     9601 tccaacaatc caaaaacata ataattcaaa aagacgataa gactattggt aagtaaaagt
     9661 ccttgcggca ttggaagccg aaaaaatttg tggaaaataa tcggcggtat cgttataccg
     9721 ccatttgagg ccccgactgt gtacaatgtg taaaccccaa gactgaacaa aagacttcct
     9781 gaaatcagtg aaaagaaatg tgaggagatc atttccactt ttggaacaat ctctaaaaca
     9841 acaggaaaaa gcagacttcc cgctacagtc ttaaaaaata ctgattttcc taataggaca
     9901 gcggctagaa gcagcatcat aagattgatg ctccaaacag taactgagcg ttggatagaa
     9961 aaggccgttt caactaaatg tccgatggcg cccactccgg cggaagctat atcgtgaggg
    10021 agcaagaacc aattcaatcc aactgtgata aagaaaagac ctaaaaatat aacgggtagt
    10081 ttttttattt cttgtgtcat tgatatctcc tataaatgtt agccataaaa ggctgtatat
    10141 ttctttactt taccaaaaaa acgaaaccga attcaaaaaa acaattgttc ttataaaagt
    10201 tatataaaat cgattgccag tttctgtttt accaattaaa atgatagtaa tgttttgtag
    10261 aaagttggaa tctgaccgat ggataatcaa agaaaaccag cattagatca attaacaccg
    10321 caagaaaaaa tggcacgagg ctctgcttgg atgaccgcca gtaatatcat ttcaagattg
    10381 ctaggcgctg tctatatcat tccctggtat gcttggatgg gcgaaaatgc taaggctgcc
    10441 aatggattat tcaatatggg atacaatata tatgcattgt ttctactgat ctctacagca
    10501 ggaatacctg ctgcgattgc aaaacaaact gcacgctata attcattgaa tgaatatggc
    10561 acttcacgac gattatttat ccgtgcatta cagatgatgg gcgggctagg cctgttgttt
    10621 gctttgttca tgtacatcgc ctctccttgg ctagctcatg cttctggtgg cggagaagaa
    10681 ctgattccaa cgatgcgttc tttgagtatc gctgtattgg tttttccttg tatgagtgtg
    10741 atacgagggt attttcaagg caatcaagaa atgatgcctt atgcgctgtc gcagattgta
    10801 gaacaggtgg cacgtatttt ttatatgcta ttggctacat tcatcatcat gaaagtcatg
    10861 gatggtgact atgtgacggc ggtcacgcaa tcaactttcg cggcatttat cggtatgcta
    10921 gcaagtattc ttgtcctttt gtattttttg aagaaacatc aagcgtatac atcggcgttt
    10981 attcactaca gcgaaaacaa aataaatatt gcaacgaagg aattgttgtt agataccgtt
    11041 aaagaagcga ttccgtttat tattgtgggt tcaggggtaa cgatcttcaa attagtcgat
    11101 cagttcactt ttatgaagat catgtctgca tccaccgagt attccaatgc acagttactg
    11161 gatctttttt cgatttttag tgccaatcca gataagttga cgatggtagt tattgcattg
    11221 gcaacatcga tcgcgtctac tgggttaccg ttgattacag aagctgttac gttgaaagat
    11281 cgagtaggtc tggcaaaatt gacaagcgga aatttacagt tgttttcatt ttttatgttt
    11341 ccggcgacat ttggtgttat gttacttgcc tatccgctaa atacattatt ttatacaccg
    11401 gattctctag gaagtaatgt actgatccaa gcaagttttg taggactctt cctaggacta
    11461 tatatgctag tttccaacat gctgcaagga atgtttgaaa acaaggcggc aattaattat
    11521 ttggttattg ggtttctagt gaaactcctt cttcaatacc cagccattcg tttatttgaa
    11581 gtatacggcc ctttattggc gacaatgatc ggatttgctg tgtcttgtac cttgatctta
    11641 aagagaatcc atgaagtagc ccgctttaaa ccaagttttg tctggcgcag gacattgctg
    11701 atctttattc ttaccttgat tatgcttttg gcttcgtgga tcacaaagat gatttttggt
    11761 gcttttttaa acgaagatag caaattccag tctctattgt tgattcttgt agtagcaggt
    11821 ataggggctt tagtgtatgg ttatttagct ttgaaaatcc gcttggcaga aagactacta
    11881 ggaccaggaa tagcgcgttt acgacataaa ttaaaaataa aataagtgaa tcagaagagc
    11941 tagattgatg ctcttttgaa atgggggaaa cgcatgcgtt tagataagtt tttagcagat
    12001 atgggacttg gcagccgcaa agaagtcaaa ggattgatca aaaaaggaac gatcgaagtc
    12061 aatggacaag tggtgaaaag cgataaagcg caagtaaatg aattcgaaga tgcggttact
    12121 tatttaggag aaatcattac gtatcaaaaa gatttttact acattttgca taaacctgca
    12181 ggagtcattt ctgctactca ggataatcat gatcaaaccg taatcgattt attggaagac
    12241 caggattatc gggaagatct ttttccagtc ggccgattag ataaagacac agagggcctc
    12301 ttgattttaa cgaatgacgg ggtgtttgcc catcagttac tatcacctaa aaaacatgtg
    12361 gagaaagaat atctagctga ggttagcggt ataatgacag aagaagatat ccgtttattt
    12421 gcagaaggac tgattattga tggcgatgag cagacattgc cggcaaaact ccaaattgat
    12481 caagtagatc aagagacaga aacttcaatt atccgtctga ttttgcatga aggaaagttt
    12541 caccaagtta agcgaatggt caaagcagta ggaaaagaag tcttatattt aaaaagaatc
    12601 cgtatgggaa aattttggct gcctaaagat ttgaataaag ggcaatatcg acccatgacc
    12661 aaagaagagc tagaacaagt gagagaaaaa taattgaatg gatagctaaa agaataagca
    12721 gagtagttgt agcgccatct gaaaagcaga cttgtccgtc tgactttcgg atggcttttt
    12781 tgtgaaattt cggcttattt ccgtagaagc tacttctgga acaccgtttg ttcggaataa
    12841 gggactgtga caagactttt gttacagtcc ccattgttcc ttgtgactca gagttagata
    12901 gtaaggacac gatctcccta atactcaggc caaaacgctg aattcacaac ctctgataaa
    12961 cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta
    13021 ttttcccgtt tttttctcta atactcaggc caaaacgctg atttcacaac ctctcctata
    13081 ctttgtttca ttttccctat actttgttta tttattctca ttattgaaag cgctataatt
    13141 acgttgcgaa tgaatcgaaa ggggttttta gatgaaaaaa cgaaaggggt tcaatcattt
    13201 ttttatgaat ctatggcgtt ataaagcact tgtcctgatg gctgtaccgg gtatgctttg
    13261 gatgattttt ttcttttaca tacctgtaat ggcgaatgtc gtagcattca aaaattttca
    13321 tatttcagca gatgggttct tggctagctt gagggaaagt ccttgggtgg gttgggaaaa
    13381 tttcaaattt ttattttctt cggatcaagc atttctcatc actaaaaata caattttata
    13441 taatgtagca tttatccttt tgaatctgct gatctcagtc gtatttgcaa tcattatgag
    13501 cgagttgaga aataaacgac tcgttaaagt ttatcaaacg atgtccttac taccttattt
    13561 tctatcttgg gtcattatca gttactttgt ttacgctttt ttaagtcctg acaaaggaat
    13621 attcaatcag tggatcactg gacatggagg agaagctgtc aattggtata atgaaccgaa
    13681 atattggccg tttatcttgg tgttcattgg tacatggaaa gggattggtt ataacagcat
    13741 tatttacttt gcatctgtta tgggaatcga tccgacttat tatgaagctg ctatggttga
    13801 tggagctagc aaatggcagc agatcaaaca tgtgacgata ccacaactta ttccactaat
    13861 gacgatttta acgattttag ccgtaggaaa cattttccga gctgattttg gcctgtttta
    13921 taacattcct aggaattccg gtgcattata tgatgtgact caagttttgg atacgtatat
    13981 ctacaatggc ctgacatcca caggagattt tggtatgacg gctgctgcag gactttacca
    14041 atcagttgtc ggctttgtct tgttgatgat cacaaatacg atcgcccgac gttttgatag
    14101 cgattctgca ttattctaag gaggaaaaaa atgaaaaaaa agaaagtgga gagagtccaa
    14161 gtccgctctt tcaataagac ggctaatttt ttctctaata taatgattgc actctttgct
    14221 atttcctgta ttttgccatt tatatttgtt atcgccatct cttttaccga tgagtccata
    14281 ttgtcgactc acgggtacag tttttggcca gaaaagttca gtatatttgg ttatacgtac
    14341 ttgttcgacc agatgcagga taaaattttc caagcgcttt tcgtcactgt acttgttact
    14401 gttttaggta cactgatcaa tagcacggct acttctttat atgcttatgc gatttcacgg
    14461 tcaaactttc cattccgtcg tttttttacc gttttttgtt tgattacgat gttgttctca
    14521 ccagggatgg tggccaatta tcttgttatg acaaatcttc ttcagttaaa agatacgatt
    14581 tgggcattga tcttgccaat ggctgtcagt cccttcaata ttattgtgat gcgcacattc
    14641 tttaaacgtt cggtctctga ttcgattatt gaatcggcac ggatcgatgg agctagcgaa
    14701 ctgcgaatat ttgttcagat cgttttaccg ttagctgttc caggtattgc gacaatcagt
    14761 ttatttgccg cattgggtta ctggaatgac tggttcaatg ctttactata catccaagat
    14821 gataagctag ttccactaca gtatcttttg atgaaaatcc aaagtaatat tcaatatctg
    14881 acacaaaatt caggagcagg aagccaattg acaggcggat tagcctcagt tccaggagaa
    14941 tctgccagaa tggcgatcgt agtcatctcg acgttgccta ttgcgatcag ctatccattt
    15001 ttccagaagc attttgtcaa aggtctaaca atcggcggag taaaagaata aagaaacaaa
    15061 aatataaatc ataaaattag gaggaagaaa aatgaagtta tggaagaaac tagcctttac
    15121 aggtgtttca gcgttgttgt tgggaacatt agcagcatgc ggaggttctg gttctaaaga
    15181 ccaggcagaa gctagcaatt cggacacttt gcagatgtat caaatcggag ataaaccaga
    15241 taatttcgat caattgatgg aagtagcaaa caaacgaatc gaaaaagaga tcggtgtaaa
    15301 agtcaatatc aattacattg gctggggcga ttacgaaaag aaaatgaacg tcatcatttc
    15361 ttccggggaa aattatgata tcgcctttgc gaacaactat gtttccaatg cccaaaaagg
    15421 agcctttgct gatttgactg aattagcgcc taagtacgct gaaaaagctt ataatgattt
    15481 agatgaagca tatattaaag gaaatctggt caatggaaaa ttatatgctt tcccagtcaa
    15541 tggaaatgtc tttgctcaac aagtacttac ttttaacaaa gctttactag ataaatacga
    15601 tctttcaatt gatggaatcc aatcttacgc tgatgcagaa aaagtcttga aggaattcca
    15661 tgaaaaagaa ccaaacacgg cagcttttgc cattggacaa ggcttcaaag tccaagggaa
    15721 ctttgattat cctttaggga atacgttacc atttgctatt gatctggatg gagatgattc
    15781 gaaaatcatc aaccaatacg ataatgaaac gtatatcgga ctgttacgta caatgcatag
    15841 ctggtacaaa caaggactca ttccaagtga cgctgcaacg agcaataagg attatccact
    15901 agaaggaaat acttggctaa tgcgtggaga aacacaagga ccgtatgatt atggcgatac
    15961 aattttgaca aatgcagcaa aacaagaact tgtctcaaaa gcaattactg ttccactaaa
    16021 atctacagct caagcacaaa tggcaaattt tgtcgtatca aatacttcaa aaaataaaga
    16081 aaaatcagta gaacttctag ggctgcttaa cagtgatcca gaattattga atgggcttgt
    16141 ttgggggatc gagggagaag catgggaaaa agtcgatggt tcagatgata aaatcaaatt
    16201 gctagatggt tatcagccaa atacacatat gtctgcttgg aatacaggaa acaacaagat
    16261 tctatataca caagagtcta ttacggatga catgattgcc aaacgtgatc aatcgattgc
    16321 tgatgcagaa acttcaccga ttttaggatt cagcttcaac actgacagtg tcaaaacaga
    16381 attaagtaat atttctaatg tcatgaatca atatttagat ggattgaata cagggactgt
    16441 tgatccagat gaaacattac cgaaattgaa agacgctttg gacaaggctg gctatgataa
    16501 ggtattgaaa gaaatgcaaa aacaatatga tgagttccga caagaataat aatgaataaa
    16561 gacaaagggg ttgtgacaaa agacgtgtca caacctcttg ttccgaataa acggtgttca
    16621 aaagccagtt tctcggtatt aagctaaata tatgtaaaaa tgtggaaagc catattcaca
    16681 aaatttttct tactactcga aactaagcgg ctatttcaca aactcttggt aaacggtgtt
    16741 caatcagctg accctcggta ttcgctcaca aaacgacaaa atatgaggaa ctatttttcc
    16801 gtttgtttct ctaataatca ggtcaaggtg ctgattgccc aacctttttt tgtataatga
    16861 gaaagtataa acttaatgtt tggaggagaa gatatgttag ggaaggtttt ggaagagtta
    16921 tttatccgga tctgggtcat tataaaacta accttgtatt tctggatata tacatttgcc
    16981 ggcgggatca tctttggatt aggtgcggca tggaaaacag tcaatgaact attttatttg
    17041 tacggattcg agtataaaga aatcacaata aaaagaggct ggaatatata taaaagaaat
    17101 tttttaagag gcaatctgct atttagttta tttttatctg gtactgcttt attgagttac
    17161 aatttatatt tatctgttca aatcaaaggg ctcatttttt tagctattga ttttatttta
    17221 ctttttgcct tgctctgcct atttgctact tatcaataca gtatgatttt agatagtgaa
    17281 tatacgatct ctgttcctaa tctgctaaag ctaagtttta tttcggtttt ttccagcttt
    17341 tcgtcttttc taaaaataat tattggtagc ggtataattt taggcgtgac ttggcaattc
    17401 aaaggattga tcctgtttgg tgtcattggt cttttgacgg tttggaatgg tacgatgaca
    17461 acacattggc gtgaagaatt agataaacag ttggaaagtt atgaataagt ttcggattct
    17521 attttcaaaa ggaaccttac taaatcgtct gttgcggaaa tacgcggtta tcatgatcgg
    17581 tgtaacgatg actgctaccg ttatttttag tatccatact tgggaacaaa atcaaaaaca
    17641 ggcagaaaac atgacaagtg atgccgttca aagcacaagc agaatgctga atgataaaac
    17701 aaccttgagt aggatcatca aaaaccagct tgtagggaat tccgaaaaga tcgaaaatgt
    17761 gacgacctac ttaacaaaac ccatagatca gtatctgatg tatgtatacg aacagcaaaa
    17821 cagtaccgat gaattagttt ctttcccaaa tcaaatcaaa gatctctacg caaattatga
    17881 agaactaagt gcgatatata tcgtgttgaa tcaactaccg gagtattatg aatcttctag
    17941 agaaaacaaa ggtggggaaa taaaaaaggg gacaccaaaa ttactagacg ccttttatat
    18001 caagttgcct atcacacaag gaggagctga gtcaggaagt atttttattg gttttcaaaa
    18061 gaaagaacta gatatgattt tagaaaatct aacgtcattc aatggactct ctttatacat
    18121 gatttctgga acgacaaatc gactatacac attccatgat aataaaatag ctaaagaaac
    18181 gtttgaaaga caagaaatga tcatcacaga gagtctgaag aaaaattcac aattgccgat
    18241 tgacgatctg gaaaaaaaca attttgttca acaccaagaa ctgtctgatg attatcgtat
    18301 attagctgta ctagataaaa aaagtgtaaa aatcgaaacg ggaaaaaatc ttgccccgct
    18361 gatcattggt atcattattt tagacaatat actgcttatc tttctttata aaacattcaa
    18421 acgatattca cagcaagtat ctatcgtcat gcaggccatg gatcaaacag cagcagggaa
    18481 tttagagacg cggatcgaca taacaaacac ggaatatgaa ctgaaggaac tttcaatcgg
    18541 tatcaacgaa atgttggata gcatcaatca gtttgtagaa gacatctaca aattagaaat
    18601 caaacagcaa gacgcacata tgcgggcgct tcaagcacag atcaatccac actttttata
    18661 taatacatta gaatatatcc gaatgtatgc aatcagcgaa ggaagtgaag aattagcaga
    18721 tgttgtgtat gcgttttccg ctttgcttcg aaacaatacg aatcaagaga aaacgatcac
    18781 tttaaaagaa gaactggact tttgcgaaaa atatgtctat ttgtatcaaa tgcgttatcc
    18841 taatcgagta gcctatcatt ttatgatcga tcctgatttg gaaaagatcg aagtacctaa
    18901 atttgtgatc cagccattag ttgaaaatta ttttaaacac ggtattgatt ttactcgatt
    18961 cgataatgcg ctaagtgtca aagtcttgca ggaaggcaaa cgggtaagga tcatcatcaa
    19021 agataatgga aaagggatga ctgaaaaacg gctaaaacag attgaagaaa aactgtctca
    19081 tcctaaagtg gaacttcacg gttctatcgg tctgcaaaac gtgaatgaac gtttacgtgc
    19141 cagcttcggc agcagttatt atatgtcgct tgagaataat gagacaggtg gactgaccgt
    19201 ttctattaca ttcaaggagg gatgagcgtg tatcaagtgt tattggtaga tgatgaatac
    19261 atgattttga atgggttaaa aaagataatt gattggcaaa gtttaggctt tcaaatagta
    19321 gcaacagcag agaatgccaa agaaggacta gctgtacttg aacagcgaca gattgattta
    19381 gtagtaacgg atgtgacaat gccagaaata aatggactgg aatttattga agcggctcaa
    19441 aaagaacgtc ataattttga atttatgatt ttatcaggat accaagaatt cgattatttg
    19501 aaaggaggta tgcaattagg cgccgtgaat tatttgatga aacccgtgaa taagttcgaa
    19561 ttggttgaaa gcctcaagaa aatcaaaaca cggttagatc agcaaaatga acaaaaaaat
    19621 caacaagaaa tctatcaaga actgttattc agtcaatggt tgaatgaaga attggatgaa
    19681 ataagtgaag aagaaataat aggacaaata agtgagaagc agcataggat agtattgatt
    19741 caactggcaa gaactcatga tactcttatc aatagatggt tgcaagaacg gcaacaaatc
    19801 ttttactatc aacgaaatta cggagaccgt gtattgatca cgttgttgtt ggaggcagat
    19861 gaagttgatg gcttctgttg ttttgttcaa gaaaactttc ctgatcagga atggctgatc
    19921 agtatcgggg aagagacaga ttctttggac aaaatccctg aaacattcca acaagcgaaa
    19981 gacaatctac agttgcatca attttatgga gataaagacg agcatgtttt ttacgcagta
    20041 caagcagaaa caaaagatca aaccatcgat ttttcaagtt tcagacgcgt gctgcaaaat
    20101 aaacaattgg aagtcgctca aaaaatgatc actgattttt ttgaacagtt tcagttagca
    20161 gccatgatgc cggaagatat acgatattcc agttttttac tgtttatgga gattcaacgg
    20221 gaattgattg atctggaaga tgaggaatat ttacaaggaa tcgaaaaaat ccatcaggca
    20281 aaaacggtgc aagaacttca gcagctactt ctgtcattca tcaaaaagca tcagagacag
    20341 aaaaagtaca gtgacaatgt ggaaaaagta atcgtaatcc tgcaccagca ttatcaagaa
    20401 ccacttacac tcaaagaagt gtcagaaaac ctgcatttaa atgtcatgta tctaggacag
    20461 ctgttcaaaa aagaaacgaa aaaaagtttt tcagcttatt tgaaccattt acgtatggaa
    20521 aaagcgaaac aactgctttt gcacagtaat caaaacatca atgagatagc aagtgagatt
    20581 ggctacaaca acaccacgta tttctctaaa ttattcaaga aaatcgtcgg cagatcccct
    20641 aaagagtacc gagaaaacag tggagaatca taaaaaaaaa agccaatgta atgaaataac
    20701 ttataaaaaa ttgtctagaa atctaatttt gggctgttct tattacttga ggcaaggcag
    20761 ctttttcatg acctctcgat aaacggagtt caaaagccag tttctcggta ttaagccaaa
    20821 tttatgcaaa aatgtggaaa gccattttca caaaattttt cttaatactc gaaactaaac
    20881 agctttttca cgacctctcc actaaatggt gttcaatcag ctgaccctcg gtattagctc
    20941 aaaaaatggc aaaatatgag gaactatttt gccatttgtc tctctaatac tcaggtcaga
    21001 acgctgattt cacaacctct caataaacgg tgttcaaaag cttgcatctg cggtaataag
    21061 accaaccaaa cgaaaaatat gaggatctat ttttgcttgg ctgttcttat tacttgatgc
    21121 aggacagctt tttcacaacc tcttgttaat tatagtttga taaggaaaaa ggcaaatctt
    21181 ttgcttgata tttcttaggg tgagggatga tccctaattg gtaagagatc gtgccgcctt
    21241 tcagcaaatc ttgatgggta aaatataatt tcgtatattc tctgtccatc cgtttgattt
    21301 tatggataaa ttgttgctgc ggccgattag gcgttgcttc aatcgtcaat tcctttccat
    21361 ttgacaaaag caaaacagcc ttgtcaatta atggcatacc gataacatat tcaccggttc
    21421 caggcgtgac aggataaaat cccagactat tgaagatata ccaagcggcc atacttccat
    21481 tgtcctcatc tccagggtaa cccattggag aatcgtcgaa ggtctgagtc atcaactgtt
    21541 taagcagtgg ctgtgccatt tcaggttgtc ctatataact gaacaagtaa ggatagtgaa
    21601 aacttggctg gtttgaaata gctaattgtc caaattctat cgcggccatc tcactcattt
    21661 cgtggatctc aaaaccatat cctcctgggt caaacgttgg gggctgattg cacagctcaa
    21721 tgagtttttc tttatatctc tcactgccac catattttcc gatcagtcct gaaaaatcgt
    21781 gataaacagc aaagctgctt tgccaagcac ttccttctgc ataatcttgt ccccaacgat
    21841 tagctgaaaa tggttctctg aacttgccat ctttatcttt tgaacgcata aatcctgact
    21901 catagtcaaa gatattttga tagttcaatg attgctgctg atatttcttc gtcatttcct
    21961 cttcttctag taccttggca acttggctaa tacaaaaatc gctataagca tagtctaatg
    22021 tgtgattgac tgattcgtgg tagtgattag gaacatagcc atatgtcaag taatcttctg
    22081 ttccttggcg tccataattt ggatgtttgc tttgaaccgt agcacctttt tccattgccg
    22141 ttagaaattc aggcatcaag tctcgtcgga tatcttttac agcagcatct gcaatgaccg
    22201 catcgatcaa tgtcccaggc ataagtccac gttcatcagg agacagccat tttggcaaat
    22261 agccactttc tctatagctg ttcaaaaaac cttccagcat ttcttcgtat ttttctacag
    22321 caatcaaaga ataaagagga taaaccgttt tatacgtatc ccaaaaccca ttatttgtat
    22381 agagaacacc aggttttata gatcgactag tcgtatcata gtggattttt tgcccactag
    22441 gatcaatttc ataaaatgtt tgtggaaata aaaacacccg atataaatta tgataaaacg
    22501 tccgcaattg ttgttgatca tggtgtgtga gctgtatacg atcaaaatag gactgccatt
    22561 gttcttgact gtgagcaagg taagtctctt tgctttggtt ttgttctagt tccaggttat
    22621 aagctgcttg ttccgagctg ataaaagatg tcccaaatcg gatagtttgt ttttttgtct
    22681 gttcaaaata caacgggatc gagtcgctat ttttgttgga aacagctaac tcatcaattg
    22741 ttaaaggata ttcaaatctc aatataaaat aaaaagaaaa atcaggatct tctgaaccag
    22801 caaaatgtgt gatttttcct tccactgtgt aaggatctat aacaaagagc tgatggcgtc
    22861 ccggaaagga taaaagtaaa ccgctgtcat ttttgctgta atcaatagat aagattccgc
    22921 catacatgct aggtatcaat gtagaacaga tgccataacg taattgacag atcgacagat
    22981 gagtcgggca aaatatactt tcttctgggc ggtaagaact ttgagcatgg aaaagggtgt
    23041 tctcctgtag ttttccattg atcggcgtaa acagcatatg actgaaatca cccatccaag
    23101 gacttggttg atgggtaaga cggtagcctt gaaaaacgcg gtcatcagga tgaaaccacc
    23161 agctgccgtt ttgatccgta gtttgcggtg caaaataatt catcccaaaa ggaacgccag
    23221 tataaggctg gcagttccca ttagagaaat ttggctgatt cgctgttgca tgtctagtat
    23281 ctatttgacc gatattcatt ttatttctcc tttgttgatt gtcttttgat gaatgaaact
    23341 ggaaatttac tatcggatgg tcgatctttt gtctctaacc aagtgaccaa agcatctccc
    23401 gcaagcttac ctaactgttc aaaatcttgt gcgatggttg tcagtggcgg gtcaacaaga
    23461 gctgctgctt ggatatcatc aaatccgata attgaaaaat cttcagggat atgataacca
    23521 tgctgtctca agagattcat ggtctggata gcgacaacat cgttttcaca aacaaaagca
    23581 gttacttcat acttagtgat ataagaaagc aattcatcta atgtcgcgct tttgtcatcc
    23641 agtgaagtgt ggaaagtcaa accagctttg tccaatgctt caaggtaacc aaggtaacgc
    23701 tgtcgaacgg attgtggatg agtctgcgta ccaaacaaat aagcgatttt tgaatgtccc
    23761 tgttcgatca aataagaggc agcaagcgca ccgccttgga aattatcgga aagaacggta
    23821 ggaaaaggta actcatagat ttttttatct aatatgacga cagggaattc tttcaatgaa
    23881 agctcaaaaa gtaagtcaag atgttgttct gtatcaagag cataataaat caatccgtca
    23941 aattcattga ttagctcttt tgctgtttta ttttgtagaa agtcaagcgt cgtcatcatg
    24001 acatcaatct gtttatcttg catcacaggg ttcaatccct tgctaaaatc accaacagac
    24061 aaatcagcga catatggaag aagaaacaga atccgtcgtg tttttgtagg agaagcaaga
    24121 atctgttccg gagaagcgga tttaacgaaa ctgcctttcc cgcgaacgcg ataaataagt
    24181 cctaattgct ctaattcagt caatgcacgt ttggaagtga ttctgcttac tttataggta
    24241 cgtgaaagtt ctttttcagt tggtagttgg ctgtctacag gtaattcacc agttaaaata
    24301 gccgtttgca aatcattaaa tattgtctgg tacaatggtt gagtcatata aacacctctt
    24361 aatgatatat catattcaaa taataccata atggatgaaa aagtaaataa aaagatattt
    24421 tttgaaagcg tagacataat tggctgtatg aagtataatc tttaaagata tatcaaatag
    24481 aaagaaggtt ttattagtgg tttataaaga tataccaaaa tcggtgcaga aatttatgga
    24541 agatatcaca caaaaatgtg gggatatcca tgcggactgg gcaaagaatt ttacagcagc
    24601 atttgccaat actctgttga caacagtcaa aaagcaaaat gacggaacca cctttttatt
    24661 gacgggagac attccagcga tgtggttaag agactctact gcacaagttc gtccttattt
    24721 agtgattgca aaagaagatg aggaattagc tgacatgatc agcgggttag tcaaaaagca
    24781 atttttttat atcaatatcg atccatatgc gaatgccttc aacgaagaag ctaacggtgc
    24841 tggccaccaa acagatcata caaaaatgaa cgattggatc tgggaaagaa aatatgaaat
    24901 tgattcttta tgctacccaa tacagttggc ctatcttctt tacaaaaata caggaaaaac
    24961 tgatcaattc aatcaatctt ttattgaagg tatcaaaaaa atcttggacg tgttcaaaac
    25021 agagcaagat catgaacact ctccttatac atttgtacga gacacgacaa gaaaagaaga
    25081 tacgctgatc aatgacgggc gaggtgcaaa aacagctttt acaggaatga catggtctgg
    25141 tttccgtcct agcgatgatg cttgccgtta tggatatctg gtaccatcca atatgtttgc
    25201 ggtggtcgtg ttaggttatg tggaagaaat ttttcaaacg atactcgatg ataaagaaat
    25261 tgtacagcaa acacagaaat tgaagaaaga gatccaagag gggattcaga atcacggacg
    25321 aacggttaat caaaaagggc aaacgattta tgcatatgaa gtagatggaa tgggaaacgc
    25381 cacagtcatg gatgacagta atgtgcccaa tctgatcgcc gcaccttact tgggatattg
    25441 ttctgaacaa gaggaagatt atctgcaaac aagaagaaca ttgttgagta aagaaaatcc
    25501 atatttctat gaaggaaagt acgcaaaagg aattggatcc tcccatacgc cagaaaaata
    25561 cgtttggccg attgcattag ctatggaagg aatgacaacg tcagacaaat ctgaaaaaga
    25621 gcggatattg aatttacttg tagcaactga cgcaggaaca caccttatgc acgaaggatt
    25681 cgatgtgaac aatcctgaaa attatacgag agaatggttt tcttgggcaa atatgatgtt
    25741 ttgcgaatta gtcatggatt actttgatat tagagtagaa aagtaggagg tatcgtaaat
    25801 gaaaaagaaa gtatatatca tttctcatag ccactgggat cgtgaatggt acatggctta
    25861 cgaacagcat cacatgcgac tgattgaatt gatagacgat ctactagagc tatttgaagt
    25921 tgatccgtcc ttcaacagtt ttcatttgga tgggcaaacg attattttag atgactatct
    25981 tcaagtaagg ccagaaaaaa gacaggcaat ccaacaagca atcaatgaag gaaaattgag
    26041 aattggacca ttttatatct tgcaagatga ttttcttatc agctcggaat cgaacgtgag
    26101 aaatatgctg attggcatgg aagaaagccg taaatgggga acccctgtca tgttaggcta
    26161 ttttcccgat acatttggaa atatgggaca gacgcctcaa ttaatgaaac aagctggtat
    26221 ttcagcagca gcgtttggcc gtggtgtaaa accaattggc tttgataatc aagttttgga
    26281 agcagaaaac tattcttccc aatactcaga gatgtggtgg aaaggccctg atcaaacagc
    26341 aatctttggt ctgctatttg ccaattggta tagcaacggg aatgagattc cagtagaaaa
    26401 agaagcagct cttgcctttt ggaagcaaaa attagcggat gcagaacaat atgcctctac
    26461 gaaccactta ttgatgatga atggtgttga tcatcaaccg gtacaaaaag atatatcaaa
    26521 agcaatccat ctcgcaaatg aactgtttcc agattacgag tttattcatt ctaattttac
    26581 tgactatctg gaagcagttc aaaaagatgt gccagaagac ttaggctcag tagaaggaga
    26641 attgacaagt caagaaacgg atggctggta tactttagcc aatacagcat ctgctcgggt
    26701 ttacttaaaa caatggaata ccaaggtcca gcgacagcta gaaaatatta cagaaccact
    26761 tgcgacgatg gcttatgaag ttagtggaaa ctatccccat gatcaattag attatgcttg
    26821 gaagacatta atgcaaaatc atcctcacga cagtatttgc ggttgttcag tcgattctgt
    26881 ccatcgggaa atgatacctc gttttgaaaa agcagatgaa gttggaaagt atcttgcaca
    26941 agattcctta gaacagctga ccgcagcaat cgatacgacc ggattcccaa aagacagctt
    27001 tccatttgtc attgtaaata ctgcaggaat ggataaaact ggtgaagcag aaataaccat
    27061 cgaattagaa agaaaaagat tcgctgaagg aatacctgaa caactatatc aagagttaga
    27121 aaatttgcct aaacgtaagt atcatgtaga aacaaaaagt ggggccacta taccagctat
    27181 tttatctgaa gaaactgtcc aatttggtta tgatttgccg aaagaccgtt tccgtgtgcc
    27241 atatatggca agaatgatca aagtgacttt accattagaa aacatgccag cattttcttg
    27301 ggaaacattc gcgcttgtag aaggggaagc gaaagcagaa gaaaaggaaa caatgattca
    27361 tcagagtgga cgaatcatcg aaaacggccc tctacatttg acgattgaaa aaaatggtac
    27421 cattacaatg gaagatcgca aaaacaaacg aaagttgaat aatctgcata tttttgaaga
    27481 tatcggcgat ataggaaatg agtatatctt taaacaacct ttctgtgatc agccaatcct
    27541 atccagtaac aaagaaaact ctgaagtaaa agtattagta gatacaccgg aaatagcaaa
    27601 aataagtatt ctacaggaaa tggaaatccc tgtttctgca gacgagcgtt tagaaaaaga
    27661 acagcagatg gttgtggaat ttcgttatcg aaaagcagaa cgatccaaag aaaaacgaat
    27721 ccttcaaata aaaacaatca tgacaatcag aaaagatagt aaaaaaatcg actttgaaac
    27781 gactctcgac aatcagatga aagatcatcg cttacgtgtc ttgtttccta caaagttaca
    27841 tgtggaacat cacgaagcag atagtatttt tgaagtggtg aagcgcccaa accatgtgtc
    27901 taaaagttgg gaaaacccca cgaatccgca acatcagcaa gcatttgtca atattcatga
    27961 tgaagagtac ggtgtaacag tcggaaactt tggtttgaat gaatatgaag taacagaaga
    28021 cggacaaatc gcagtgacgc tacttcgcag tgtgggagaa ctaggcgatt ggggatattt
    28081 tccaacacca gaagcacagt gtctaggtga gcatcggttc aattacagca ttgaactaca
    28141 tggaccagaa gaaaaattct ctacttattt gcatgcatac gcagcacaga ttcctttttc
    28201 cactcaacaa atcaaacatc atgaaggaac attgatttca aaacaacaat atttaacgat
    28261 aaaaagtgaa acgtttgcaa ttacagcttt gaaacgcagc aagtttagtg ataaagtagt
    28321 agtaagaggt ttcaatatgt ctagtcattt agaaaaattg gaaataacta aagacaatgg
    28381 aaaaactgtc atattgaatc tgcttgaaga accaacgaag caagcggttg tcccaataat
    28441 ccaaccttat gagattcgga caatcggatt cgaggaggaa aacgaatgta tggcggaata
    28501 gaagcaggcg gaacaaaatt tgtgtgtgcg gtttcagatg gtggagaaat tttagaaaaa
    28561 ttaagtatcc ctaccacaac accagaagaa acattggatc aggtatttga attttttgat
    28621 cgttatgaat tgaagggaat cgggattggc tcattcggcc cgattggtat cgacaaaaca
    28681 aaagataatt acggatacgt tttggcaact cccaaaaaag ggtgggcaca attcgatttt
    28741 cttggcacaa tcaaggaacg ctacaatatt cctgctgctt ggacaacgga tgtcaatgct
    28801 gctgcatatg gggaattgaa gcaaggagca gcacaaggaa aaaatagttg tatttacctt
    28861 accgtgggaa caggaatcgg tgcaggtgtc gtgatcaatg aagaaatttt ttcagggatc
    28921 gcacatcctg aaatgggaca tatttgggtg aaacgccatc cagatgacca ttatgaaggt
    28981 acttgtcctt atcataaaga ttgtttagaa ggattagcag caggaccgtc tattgaggca
    29041 cgcacaggga tcaaagggca agatctgccg caagatcatc ctgtttgggc tattcaggct
    29101 tattatattg ctcaagcact gatcaactat acgttgacgt tagcacctga aaagattatt
    29161 ttaggcggtg gggtaatgaa tcaggatcat ctccttcaaa aaatccgtca gcaatttgtt
    29221 gaattgatgg gtggttatat ggaaacacct caagtaagtg aatatatcgt tcgttgggga
    29281 ctgccgaatg aaagtgggat tatcggtagt ttgctgttag cagaacacga acatcaaaag
    29341 taagcagaca aattacacaa aaagaacaga gtcttatcat tatctgctga taagactctg
    29401 ttctttttta tttctattcc cataatccag gtaaagcttt accgactatt ttttcttgag
    29461 taaatggatg gatcatgtgc agttctaatg catggagcat cagtcgttca gctgttctat
    29521 tttggtagag agggtctcca acgatcggat gtcccttatg agctaaatga actctgatct
    29581 ggtgtgtacg tccggtttcc aaaacacaat agacttgtgt ttgttcagaa agtactttgt
    29641 tgacagtgac atgtgtcaag gcgctctgac catttttatc atctacgacc ctttttctcc
    29701 gatcatggcg atctcgtcca attttattgg tgatggtcat atctttggca atttctcccc
    29761 atacgatggc ttgatatctc cgatagatca ttttttgttc caacattctt ccaagtatcg
    29821 gcaagacaaa tggatttttt gcaaataaaa cggcaccgct tgtttctttg tccaagcggt
    29881 ggacaacgta aggtcgttgc tgtttagtgt cgagataagc agctaaatga ttgagtaagg
    29941 tactgttttc tgtcggttca tttggatgag tcttcattcc tgcaggctta tccactataa
    30001 tcaaatgctc atcttcatat aaaacacgga tgtgcttcgc atctcctaat tgaacttctt
    30061 gataattata atctgtttct tcgaataaca atgtgatctg gtcattgccc tttacttcat
    30121 gatggaacaa agcaggttgt tgattgatcc aaacgttttt acgtatacgc aaaaagtgtc
    30181 gaacctttct aggaactaac cattcctttt caagcaagtc gcgaattgtt gtttcaggat
    30241 ggttcatagg taaagtgatc gtgattttca caagtgtact cctttcagtg caattgcaga
    30301 ctaattgtac catttttaaa acatatttaa gaaaaaactt acatttttct gttcattctt
    30361 atgttactct acttgcacta acgtaaaaaa acatattgaa ctacaactta agcaggaaga
    30421 aaacactctt tcactatggt aaaataagac gattgaatca aatagacagg agaagaagca
    30481 aatggatttt caaagcattt tagaaaagat aaaagctgct ttgatcagtt tttggcgttg
    30541 gatcagacca tatctcggac aattccatcg atggcgaaag cgcatctgga aaaaatatca
    30601 tgtgaacaaa ttgattttgc tgattggttt gatctgtgtc ttagtgacaa gtatctacct
    30661 ctttatttta gcaaaacaag caaatgtcga aacgttaaaa tcaggattaa gccaatcgac
    30721 agtcatttat gataagaaaa acgaagaagc tggcacactg tacgcccaaa aaggaacata
    30781 tgtagaatta aacgcgattt ctccctatat ccaagatgca gtaatctcga cagaagatag
    30841 gaatttttac gagcatcacg ggtttgatat caaagggatt gcccgtgcag cagtccgaat
    30901 ggtcttgtct ggcggaacat cagggggcgg aggaagtacg atcactcagc agcttgccaa
    30961 aaatgcgtat ctgacattag accaaacgtt tgatcgaaaa gcgaaggaat tatttttggc
    31021 aatcgagatc gaaaagaagt acagcaaaga agaaatcttg accatgtatc ttaacaatgc
    31081 ctattttggc aacggggtat ggggtgtcca agacgcttcc agaaagtatt ttggagtaga
    31141 tgcaacgaat gttacgctgt ctgaggctgc tactttggca ggaatgctga aaggtcctgg
    31201 tatttataat ccgatcgatc acccaaaaaa tgcgaatgat cggaaaaaca cagtactaag
    31261 tgtaatggaa gaaaacggaa aaatcacaaa agaacaagaa caagcagaaa gccagacaga
    31321 tatcagcgcg tatcttaatg acacatacga taattcagat tctggttatc gttatcctta
    31381 ttattttgat gcagtgatcg atgaagcagt taacgagtat ggtcttgatg aagaagatgt
    31441 catgaataaa ggctataaaa tctatacagc tttagatcag gattatcaaa agcaattaga
    31501 agctacttat caaaacagtg cattattccc agcaaatgct tcagatggtg ccatggtcca
    31561 atctgcttca gtagctttag atccgaatac aggtggtgta caagcactag taggacgaag
    31621 aggagatcat gtctttagag gattcagctt tgctacacag atgcgtcgtt caccaggatc
    31681 aacgatcaaa ccattaagcg tatatacacc agcactggaa gctggataca agccttccag
    31741 tatcttgaaa gacgaaccgc aaagttatta cgatgcgcat aattttgacg ggacatacca
    31801 aggagaagta ccgatgtatc aagctgttgc acaaagtttg aatttgcctg ctgtatggct
    31861 tttgcatgag atcggtttac aaaaaggata tgataaagca gaagaattcg gcctgccttt
    31921 agcaaaatct gataagtatt atggcttagc ccttggtgga ctggaaaaag gagtatctcc
    31981 attgatcatg gcgggtgctt acagtgcatt tgccaatgat ggtcagatgt atacgccgca
    32041 tcttatcacg aaaatcgttg attcgactgg agcggtgatc gtcgataaca caaacaaaaa
    32101 accaaaacag gtcatatcaa aggaaacagc cgatgaaatg accagcatgc ttcttggtac
    32161 attttcaaat ggaacagcgg ctgctgcgaa tcctgcaggt tatacgatag cagggaaaac
    32221 aggaaccaca gaaactaatt tcgatgccac aaaagcaaat gaccaatgga tgatcggtta
    32281 cacgccagac gtagtgattt cgacatggat gggttacgaa gaatccagca agctgcacta
    32341 tttggaaggg acaagtggaa atgttgtcgg gaaagtcttc aaatcagcgg cagaaggcat
    32401 ccttccgtat acttcaaaaa caggatttag tgtagcagat gcctatgcca caggaggaca
    32461 agtggtagct gcagatcaag ttggaaacac aggaaattct aatggagagt ctggaaattg
    32521 gcaagataac ttgaatcaat atggtgaaca agcaaaagaa gggctgaaaa acttcggcga
    32581 tatggtgaaa gaaggcgttc agggaattgg tgaagcggct aaagacctct ggcggaaata
    32641 tcaaggagag tagccccttt gaaaacgaat aaccccatgt tacaatagag agtaactact
    32701 aaaagaaaag agggcataac atgtcaaaca tctacgatag cgcgaatcaa atcgaacgtg
    32761 agatccgtga attaccagaa ttcaaagcgt tgaaagaagc gtacgagaaa gtacaagcaa
    32821 acgaagaagc acacaaactg ttcaaagact tccaagcgat gcaaatcgaa ttacaagaaa
    32881 aacaaatgag tggacaagag ttcagcgacg aagatgcaat gaaagcacaa gaaatggctg
    32941 tgaaaatcca atcagaagaa gtaatcaatg acttgatgca aaaagagcaa ggcttcagta
    33001 caatcatcaa tgacttgaac cgtatcatca tgacaccagt tcgcgacctt tacagcgaat
    33061 aaaactattt tatgaaacaa cagagggtgt gaaagagacg ttcggccttg agcgatgaca
    33121 aaattgcttc ttattgccga taggctgtct cttgaacacc atttaccaag aggtcgtgag
    33181 cctaccgttt aactctgagt tacaaggaac aatttcaaaa aacagcttct catgtttgat
    33241 gactattgtg acttgtgacc gaggagttgg caggagaaca ccgtttattc agaaatagga
    33301 gctacgacaa aagtcttgtc atagctccta ttttttgtca ttcatttttc aagcggtaga
    33361 aatagccttt ttgagctaac agtttttcgt aagtacctat ttcaacgatt tttccttcat
    33421 cgatcacaac gattttatct gcctctttga tcgttgaaag ccgatgagcc acaataaaag
    33481 tagtgggtgt ttctgtcagg taattcaggg cttgctggat ttttttctct gactggttat
    33541 ctaaagctga ggttgcttca tctagcaaaa tgatttttgg ctgacgtatc aacgctcgtg
    33601 caatggagat acattgcttt tggccaccag acagcttgtt gccatgttcg cctactaagg
    33661 tatccagacc atcaggaagc tggtcaatca gtgaagaaag ttgcgcagct tcgatgactt
    33721 catctaaacg ttcttttgat acgtttttca agccataagt gatgttctct ttgatcgaag
    33781 cggagaacaa caaagtggtt tgaggaacaa cggctaaata atttcgcaca cttcgcatat
    33841 ccagttcatc caaaggctga tcatctagaa aaatttttcc tgaagtcggc tggataaatc
    33901 caatcaataa gttaaggagt gtagattttc cagagccaga tggcccaaca aaagcaattg
    33961 tttctccagc tttcacctct agagaaaaat gatcgataat cggtttgagt gagtccggat
    34021 aaagaaaaga aacatcctca aaacgaaaat ttccatccaa atgttggatt tttttcttac
    34081 cgtgataagt ttctacatcg ccagcaatca acagttcgcc aatagaagtg atagattcca
    34141 tgccttttga aatcgtagga atcagcgtga tcattccaga aacggaattg acgatcgtcg
    34201 tgaaatacgt ctgatacatc acgacatcgc cgggttggat gcgcccttgt aaagctaata
    34261 tcccagtgaa actcaaacaa atcagctgaa atatctgaaa actagcccag ctgactgatc
    34321 cgaaaacaga ttgcaggata tctaagtgga atcctttttc atagatttga gtaaaatgct
    34381 tatttaagcg agttgtttcg tgtttttcta acccatgagc tcgagcaatc ggtgctaatt
    34441 cgatcacttc gatcactttt gcagaagtct cttccatttc ttgcctgaag tctgagttgg
    34501 actgtctgat ccttttacgg aaaaagagag taacgaatgc ggcgagagga acagtcaata
    34561 agaaaaacat gaaaacaaca ggacttttat aaagcgtgat acctaaagct acgaataaat
    34621 tgacagcgat atttaatccg ctgacaaata cttgagagga caacgtttgg atagcttcta
    34681 catcacggat gatctttgac tggattcgtc cagattgcaa ttctttttga taaggaatag
    34741 atagttcttg gattttcttg ataagggtcg ctcttagtcc agcttctact tgacggatcg
    34801 aagtgctatg gtattttaca tgaaaataat tcgtcaatat attttgacca atcagacaag
    34861 ccatcaaaaa agcgttgaaa taaatggcct gcaactgaga agaatctttc gatgaagctg
    34921 cattgattac attggcaata gcgatcggca ttaaccaaga tggaagatgt ttgataataa
    34981 aaaagagtcc tgacatggca aaacgccaat aatttccctg ataaagatgc agcaatgtct
    35041 gaaaagcatt tgcatgatat ttttgataac ttttctgtat tcgttcctcc ataatcttct
    35101 ccttaacaat cttggtaaat aaactgcaag tgttctattg cttcaggaac ataaatctca
    35161 ggagtagctt caagagtggc gtacattaga ggacgctcat atttgatata atgcagtacc
    35221 gggcggaaat ctaaacagcc cttgccaaca ggtaccatgc ggatctttcc attttccatg
    35281 atatagtctt tgagatgaag cgctgtaata taaccatgta aattgtccaa ggcacctcgg
    35341 atcacttttt cctgatcagc atgattttct ttatgcatca aattcgcaca atctaaaatg
    35401 atttttaaat ttggtgaagc tacttcatcg attaaacgtt tagctaactg atagttatag
    35461 attggatgat tgatccctgc ttcaacagca acagttacgc caaaattttc tgcatgagcg
    35521 actaattcaa tgatagaatt tctggcgatc tgataagctt cttcagtaaa attttctttt
    35581 gtgtaaccga cagagacact accggtttcc gtagcaatca tcttggcttg ataggcagag
    35641 cacagagcaa tttgctgttt gaaagttgcc aatgcttgtg cacgaacttc ttgatttttg
    35701 ctggataggt tgatatagca tcctaaaatg gaaagttcga tattgttttt ttggaagtat
    35761 tcaccaaaat aggcagcact cccaagtgtc atgtcagtta atttaagttg ttcaggaaat
    35821 gctttttgtg gtgcaaattg gatatgggac aagtgaagct gtgatacttt ttgaacgatt
    35881 tcttcacgat ttcgaacatc taaatcgtgg gcacggatgc ctaaatttaa tggaaacatc
    35941 tcaaactcct ttttgtaaat aattagcaag aggcagacgg gattctttta tcaattcaac
    36001 aattattcgg gcaactttat cagcgccttc tggactaaag tgggtattgt cttttagtcc
    36061 ttctgggtaa tttttacaag tatcaggcat aagatgcagg tagaattttt ttgtctcttc
    36121 ttttgagaag gtctggaaca attcttgtga tcttgagaac acatctaaaa gaggaatatg
    36181 gtgtttctca gcaaatgcac gcatcgcttt tggatagtct ccaagtatat ctggattcaa
    36241 tgttccgttt tctaagtaat ctcgtcgcgt cacagatgtc agtaagacca tttggacgtt
    36301 cgcttttttt gcgcattcaa aaaatatctg cagatttttt aaatagctac cgaagggaag
    36361 cgtacctctt tcttcttgga ttttctggtc gttatgtcca aattgtacaa ataagaaatc
    36421 attcggctga aactgtgaag ctagacgggc taaccttcct tcctggataa atgatttggt
    36481 gctgcgtcca ttctttgctt ggttattgat ctggatctcg ggtgaaaaat aagcagagat
    36541 tttttctccc caacctgtct cgggacgctt gttttcatct ttttctgccg cagtagaatc
    36601 accggcaata tggatagtag gcatgttatc tcttctttca taaaggttta taggcaatga
    36661 agcagaacag caagagaaga agacggagca
//
LOCUS       DAZKNV010000026        34687 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000026 DAZKNV010000000
VERSION     DAZKNV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.026"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            591..1280
                     /locus_tag="ACG8M1_001413"
     CDS             591..1280
                     /locus_tag="ACG8M1_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0422134.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACG8M1_001414"
     CDS             1267..2475
                     /locus_tag="ACG8M1_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFQ0422135.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACG8M1_001415"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACG8M1_001415"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFQ0422136.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG8M1_001416"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG8M1_001416"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFQ0422137.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACG8M1_001417"
     CDS             complement(6578..7273)
                     /locus_tag="ACG8M1_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFQ0422138.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG8M1_001418"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG8M1_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFQ0422139.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACG8M1_001419"
     CDS             complement(8472..8663)
                     /locus_tag="ACG8M1_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFQ0422140.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACG8M1_001420"
     CDS             complement(8684..9574)
                     /locus_tag="ACG8M1_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFQ0422141.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACG8M1_001421"
     CDS             complement(9561..10328)
                     /locus_tag="ACG8M1_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0422142.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG8M1_001422"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG8M1_001422"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFQ0422143.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG8M1_001423"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG8M1_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFQ0422144.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG8M1_001424"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG8M1_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFQ0422145.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACG8M1_001425"
     CDS             14899..15282
                     /locus_tag="ACG8M1_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422146.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG8M1_001426"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG8M1_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFQ0422147.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACG8M1_001427"
     CDS             complement(16226..17044)
                     /locus_tag="ACG8M1_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFQ0422148.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG8M1_001428"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG8M1_001428"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFQ0422149.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG8M1_001429"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG8M1_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFQ0422150.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="ACG8M1_001430"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="ACG8M1_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFQ0422151.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="ACG8M1_001431"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="ACG8M1_001431"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFQ0422152.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="ACG8M1_001432"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="ACG8M1_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFQ0422153.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="ACG8M1_001433"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="ACG8M1_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFQ0422154.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="ACG8M1_001434"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="ACG8M1_001434"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFQ0422155.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="ACG8M1_001435"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="ACG8M1_001435"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFQ0422156.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /gene="rpsF"
                     /locus_tag="ACG8M1_001436"
     CDS             27086..27385
                     /gene="rpsF"
                     /locus_tag="ACG8M1_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFQ0422157.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="ACG8M1_001437"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="ACG8M1_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0422158.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="ACG8M1_001438"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="ACG8M1_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFQ0422159.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="ACG8M1_001439"
     CDS             28352..30325
                     /locus_tag="ACG8M1_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFQ0422160.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="ACG8M1_001440"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="ACG8M1_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFQ0422161.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="ACG8M1_001441"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="ACG8M1_001441"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFQ0422162.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="ACG8M1_001442"
     CDS             33204..34496
                     /locus_tag="ACG8M1_001442"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFQ0422163.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10569 a         6743 c         6858 g        10517 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaa
//
LOCUS       DAZKNV010000027        34684 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000027 DAZKNV010000000
VERSION     DAZKNV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.027"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(127..975)
                     /locus_tag="ACG8M1_001443"
     CDS             complement(127..975)
                     /locus_tag="ACG8M1_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0422164.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1199..3139)
                     /gene="thrS"
                     /locus_tag="ACG8M1_001444"
     CDS             complement(1199..3139)
                     /gene="thrS"
                     /locus_tag="ACG8M1_001444"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFQ0422165.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3476..3655)
                     /locus_tag="ACG8M1_001445"
     CDS             complement(3476..3655)
                     /locus_tag="ACG8M1_001445"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFQ0422166.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3702..5525)
                     /locus_tag="ACG8M1_001446"
     CDS             complement(3702..5525)
                     /locus_tag="ACG8M1_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0422167.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5803..8082
                     /gene="helD"
                     /locus_tag="ACG8M1_001447"
     CDS             5803..8082
                     /gene="helD"
                     /locus_tag="ACG8M1_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFQ0422168.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8175..8822)
                     /locus_tag="ACG8M1_001448"
     CDS             complement(8175..8822)
                     /locus_tag="ACG8M1_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422169.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9001..9720)
                     /locus_tag="ACG8M1_001449"
     CDS             complement(9001..9720)
                     /locus_tag="ACG8M1_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0422170.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9851..11002)
                     /locus_tag="ACG8M1_001450"
     CDS             complement(9851..11002)
                     /locus_tag="ACG8M1_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFQ0422171.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11219..11959)
                     /locus_tag="ACG8M1_001451"
     CDS             complement(11219..11959)
                     /locus_tag="ACG8M1_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0422172.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11963..12286)
                     /gene="rsfS"
                     /locus_tag="ACG8M1_001452"
     CDS             complement(11963..12286)
                     /gene="rsfS"
                     /locus_tag="ACG8M1_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFQ0422173.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12343..12936)
                     /gene="yqeK"
                     /locus_tag="ACG8M1_001453"
     CDS             complement(12343..12936)
                     /gene="yqeK"
                     /locus_tag="ACG8M1_001453"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFQ0422174.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12920..13570)
                     /locus_tag="ACG8M1_001454"
     CDS             complement(12920..13570)
                     /locus_tag="ACG8M1_001454"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFQ0422175.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13580..13891)
                     /gene="yhbY"
                     /locus_tag="ACG8M1_001455"
     CDS             complement(13580..13891)
                     /gene="yhbY"
                     /locus_tag="ACG8M1_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFQ0422176.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13907..15016)
                     /gene="yqeH"
                     /locus_tag="ACG8M1_001456"
     CDS             complement(13907..15016)
                     /gene="yqeH"
                     /locus_tag="ACG8M1_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFQ0422177.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15013..15540)
                     /locus_tag="ACG8M1_001457"
     CDS             complement(15013..15540)
                     /locus_tag="ACG8M1_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFQ0422178.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15720..16505)
                     /locus_tag="ACG8M1_001458"
     CDS             complement(15720..16505)
                     /locus_tag="ACG8M1_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFQ0422179.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16498..17367)
                     /gene="accD"
                     /locus_tag="ACG8M1_001459"
     CDS             complement(16498..17367)
                     /gene="accD"
                     /locus_tag="ACG8M1_001459"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFQ0422180.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17368..18747)
                     /locus_tag="ACG8M1_001460"
     CDS             complement(17368..18747)
                     /locus_tag="ACG8M1_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFQ0422181.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18755..19174)
                     /gene="fabZ"
                     /locus_tag="ACG8M1_001461"
     CDS             complement(18755..19174)
                     /gene="fabZ"
                     /locus_tag="ACG8M1_001461"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFQ0422182.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19199..19675)
                     /gene="accB"
                     /locus_tag="ACG8M1_001462"
     CDS             complement(19199..19675)
                     /gene="accB"
                     /locus_tag="ACG8M1_001462"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFQ0422183.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19678..20913)
                     /gene="fabF"
                     /locus_tag="ACG8M1_001463"
     CDS             complement(19678..20913)
                     /gene="fabF"
                     /locus_tag="ACG8M1_001463"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFQ0422184.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20932..21669)
                     /gene="fabG"
                     /locus_tag="ACG8M1_001464"
     CDS             complement(20932..21669)
                     /gene="fabG"
                     /locus_tag="ACG8M1_001464"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFQ0422185.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21681..22598)
                     /gene="fabD"
                     /locus_tag="ACG8M1_001465"
     CDS             complement(21681..22598)
                     /gene="fabD"
                     /locus_tag="ACG8M1_001465"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFQ0422186.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22705..22929)
                     /locus_tag="ACG8M1_001466"
     CDS             complement(22705..22929)
                     /locus_tag="ACG8M1_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFQ0422187.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22982..23944)
                     /locus_tag="ACG8M1_001467"
     CDS             complement(22982..23944)
                     /locus_tag="ACG8M1_001467"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFQ0422188.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23954..24394)
                     /locus_tag="ACG8M1_001468"
     CDS             complement(23954..24394)
                     /locus_tag="ACG8M1_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0422189.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24700..25665
                     /locus_tag="ACG8M1_001469"
     CDS             24700..25665
                     /locus_tag="ACG8M1_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFQ0422190.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25722..25952)
                     /locus_tag="ACG8M1_001470"
     CDS             complement(25722..25952)
                     /locus_tag="ACG8M1_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFQ0422191.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26038..26925)
                     /locus_tag="ACG8M1_001471"
     CDS             complement(26038..26925)
                     /locus_tag="ACG8M1_001471"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0422192.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27014..28237)
                     /locus_tag="ACG8M1_001472"
     CDS             complement(27014..28237)
                     /locus_tag="ACG8M1_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0422193.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28254..29300)
                     /locus_tag="ACG8M1_001473"
     CDS             complement(28254..29300)
                     /locus_tag="ACG8M1_001473"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0422194.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29464..31191)
                     /gene="ptsP"
                     /locus_tag="ACG8M1_001474"
     CDS             complement(29464..31191)
                     /gene="ptsP"
                     /locus_tag="ACG8M1_001474"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFQ0422195.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRGLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(31191..31457)
                     /locus_tag="ACG8M1_001475"
     CDS             complement(31191..31457)
                     /locus_tag="ACG8M1_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFQ0422196.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31936..34170
                     /locus_tag="ACG8M1_001476"
     CDS             31936..34170
                     /locus_tag="ACG8M1_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0422197.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34318..34638
                     /locus_tag="ACG8M1_001477"
     CDS             34318..34638
                     /locus_tag="ACG8M1_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFQ0422198.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPQH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT         9802 a         7493 c         6052 g        11337 t
ORIGIN      
        1 ttaaaaaata aacttatttt tgaaaattat gttttcttaa gtcgtgaaac actttgatgg
       61 atcatttatt tgtggaaaac tacgttttgt tattctaaaa aacttatata aaaaatagta
      121 aggtttttat ttcgaatcca taaaatattc ttggattgct tctcgtgttt ttttcacttt
      181 ttcgctaagc ttttcgtttt tagccatata gaaataaaaa atgatatcga tcgtagcaaa
      241 ttgggccaaa agtgaattag ttgccgcact tcgattcgtg atttcttttg gtctagatgt
      301 ttgtacgagt acatcggcta tcttgctaag cgggttattt ccaaattgcg tcaacgcaat
      361 gatttcgata ttcatgcttt tcgccagctc ggctaatgcg actacatctg cacttctacc
      421 tgagtttgaa acaagccaaa gcactttctt tttctcattg ctgacaagtt gcgggagcaa
      481 gacgtggata tctttttcaa aaatgattgg cttaccgaca cgagaccatt tttgcagaat
      541 atcttctact actaaagaag aggcgccaac cccatataaa aaaacagtct ctgccgattc
      601 caaacactct acgacttttt ggatcgtttc ttcttctaga atatctactg tttcttttat
      661 cgctacttgt gcattgttac caagtttgtt tttgatagag taaaaggact catttgcttc
      721 tatatcacta aaaccttcat cgattccagt ctgtagttct gttgaaatcg tgattttgaa
      781 gtccgtcaga ctttgaaaac cgattttttt ggaaaaacgt acaactgtcg gcgcactcaa
      841 cccggaagct tctgctaatt cattagctgt cattgtaggg accttctcaa tattaccgat
      901 aatgtagttg gccaactttt tttctgctga agaataatct tccatcatac tttcaatacg
      961 actaattacg ctcataagtt cctccaccct tttaatgata gtctatgtaa gtataccata
     1021 tcagaccctt attcacggtc gtatactgga taaaaaacaa aaaaacaatc cgcccaacag
     1081 aatatcttat cccatcaatc ccacagattc tattgagcat ctgtgtcttt gaggaatacc
     1141 tgttatctat tgttcggatt gctttctatc tactactttt ttacaggaaa tttacctatt
     1201 agttttctct gctgtaattt ttgacttctg cttccatagc atcaataaag atattcaaat
     1261 cttctacagc tgtttcttta cttccataac gacgtacgtt cactgttgca tcttccaatt
     1321 ccttgtctcc aacaactaat tggtaaggga tcttttgtgt ttgagaggca cgtatcttat
     1381 agcccatttt ttcattacga tcatcaactt ctacacgcaa ccccttcatt tgcaaacgtt
     1441 ctttgatttc ataagcataa tcgccatgtg catcaacaga aacagggatg attgttgctt
     1501 gtataggtgc caaccatgtt ggaaaagcgc ctttgtatac ttctgttaaa taagcgacaa
     1561 aacgttccat tgtagaaaca attccgcggt ggataactac tggacgatgc gtattttccc
     1621 cgtcttctcc aacatatgtc aaatcaaagc gctctggcaa taagaagtct aattgtatag
     1681 ttgataatgt ttcttctgta ccaagagctg ttttgacttg aacatctagt tttggtccgt
     1741 aaaaggctgc ctcgccttct gcttcaaagt aatctagttc taattcatcc atagcggctt
     1801 tcagcattgc ttgggctttt tcccacattg cgtcatcatc aaaatattta tctgtattgt
     1861 ttggatcgcg atagctcaag cggaaacgat aatctgtaat attgaagtca gcatatactg
     1921 ccaccatcaa ttcaagcgta cgtttaaatt catctttgat ttgatcagga cgaacaaatg
     1981 tatgaccatc attcaacgtc atttctcgta cacgttgtaa acctgacaaa gcacctgatt
     2041 tttcatagcg atgcatcatt cctaattcag cgatacgaat tggtaattca cgataagaat
     2101 ggatcgtgtt tttgtagacc atcatgtgat gagggcagtt cattgggcga agaacaagca
     2161 tttcgccatc tcccatatcc attggcggga acatgtcttc ttgataatga tcccagtgtc
     2221 cagatgtttt gtacaactca acatctccca ttattggtgt atatacatgt tggtaaccta
     2281 gactaacttc tttgtctacg atataacgtt cgatcgtgcg tcggattgtt gccccttttg
     2341 gaagccagaa tggcaaacca gaacctactt ctggggaaac catgaacaag tcaagttctt
     2401 ttcctagttt acgatggtct ctttcttttg cttcttcacg gagacggata tattctttca
     2461 aagctttctt gtcaaaaaag gctgtcccgt atacacgttg catcatttga ttgtttgagt
     2521 ttccacgcca ataagcacct gccactgata ataatttaaa tacttgtata cggccagtgg
     2581 atggaacatg tggtccacga cacaaatcga tgaattcgcc ttgttgataa gcagtaatca
     2641 cttcttcttc tggcaattca ctaatcagtt ctactttgta cggatcactt gcaaaaattt
     2701 ctaatgcttc ctgttttgaa agaacacggc gttcgatcgg cagattttct ttgacgattt
     2761 tcatcatttc tgcttcgatt gccggcaaat cttctgcagt tacttggttt tgtccattat
     2821 ctgtatcgta gtaaaaccct gaatcgatag ctggtccaac gccaaagtgg atatttggat
     2881 agaggcgacg catggcttgg gccatcaaat gagctgctga atgacggact aagccaagtg
     2941 catcttcatg gtctggtgtg atgatctcaa tacttgcatc ttcctcgatt ggacgagtca
     3001 aatcaacgag ttttccgttc actttaccag ctaaagcttt ttttgctaag ctttttgaaa
     3061 tgctttcagc aattgccaat gttgttgttc cagactcaaa ttctttgact gcaccatctg
     3121 gaaaagtaat ttttatcata atagtttcct ccttgaaatg ttttgattga tcagatcatc
     3181 aagctgaaaa acaaaaaaat cctagcatct cttgaaaaga gatactagga cgaaaagttc
     3241 gtggttccac ctaatgttca aacgcaaatg cgttcctcaa gcgttgtaac ggtccgaccg
     3301 cccttgcttc aacaagggtt tcgaaagtgg tcatcctttg gttttctcct ggaaaagttt
     3361 cagcctagct tttcctctct tatcgaagac tctcaaattc agttggcttt ctcatcaatc
     3421 aattatgtgt ttatttaacc actaataaat agaaaaatca agtgggaaac taaacttatt
     3481 ttttccattc cccatttaca ccgtatgttc cttttttcat ctcattgatg atgacatgga
     3541 tgtgttcttt tggtgcctgc gtgtttttat gaacagcttc cgtgatatct ttcatcatat
     3601 tttctaattg ttccggactg cgaccttcta ctaattcgac atgtacgaat ggcataatgc
     3661 tctctcctct ttctgatcgt tcttttttca actcgattct atcatactat gtttgtcttg
     3721 ggtactgaat caggaaaaat ggctggatct ttttttgctc tcaaggcact caaaatagag
     3781 accgtatcca cgacttcttg caaaacagct ccgaataatg cggggattag tcccgtactt
     3841 gcaattaaca tcaaaaaaat acaaataaag atgccaatca gtacagactg tttcgctatt
     3901 ctcatcgtat ctcttgaaat cactactgct tttgctacac gcaagagatc atctttcaag
     3961 atgaccgcat ctgcactttc actagcagct gtagaaccat gagcccccat tgcaataccg
     4021 atatctgcag cagcaagtgc tggtgcgtca ttcacgccgt ctcctaccat cgcaacaggt
     4081 ctttgatctt tagggatact ttctaaaatg gtcagtttat cttgaggcaa gctacgggca
     4141 tgtacagaat ctaattggac tttttctgca atcgtttgag caatggcaga tccatccccg
     4201 gtgatcatca tcaaattttt cacatcaagt tttcttagct ccttgattgt ctttgctgct
     4261 tctgggcgaa tctgatccga aaataggatc gttcctgcaa aagatcgatc aattgttaca
     4321 tagattgctg tattggacgt ttctatttct tcagctgaaa caaaagaggc acgtccaatc
     4381 tttacttcat gattattgac tactgcttgg attccttgac cggtcacttc tttcagttga
     4441 ctaacaggat acagttggct gtttttcacg ttgttcacta acgaacgagc taagatatgg
     4501 ctagattcct gttctgcact agctgcatac agaagtagct cttctttttt tattccattg
     4561 actggctgaa tcgcctctac ttccaatatc cctttggtaa gcgttcctgt tttatcaaaa
     4621 gcaatcgttt ttgtacgtgc gagcttttca atcgttgttc cagtttttac aacgatcccg
     4681 tttttacttg aacggctcat tcctgcaact aaagcaatgg gcgcagctag aatcagtgga
     4741 caaggtgatg ccactaccag tacctcagca aatcgtaaag ggtcttttga gaaccaccaa
     4801 gaaataccac cgatcaaata agcaatcaac gtgaaaggga ctgcataacg atcagctaaa
     4861 cggacaaatc gggcaggctt ttcttttgat tcttcgacta gtttaataat catttgatac
     4921 tggctgtctg cggcacgttt ttcagcgatc atttggatcg atccgtctcc atttaaagac
     4981 cctgacataa tctgatctcc aggtttcttg gtttccgggc gggactcacc tgtcaaagaa
     5041 gattcatcga ccgaagattc tcctttggtc actcgaccat ctgcgggtac aagttcgcca
     5101 ggcttgacta gtaactggtc atcaatattt atttcatcga ttactatatc ctgcaatttt
     5161 ccttctttga atcgatgggc aattcttggg gtgttatcta acaaagactg cagttcttta
     5221 cccgctcgtt tattcgcgta atcctctaga ctatctccgc ccgtaagcat gatcaatatc
     5281 atcaaactag cccagtattc tttgacggct aatgttgcaa ggattgcggt aatcgctaat
     5341 acatctacgc catatcttcc tgaacgtaac gtcttgatca tttccaaaaa catcaagaag
     5401 gcgagaatcc ctccagtaaa tgcgacaatc gcaaatgcaa gggccggctg gtgaaaaaca
     5461 aattcactta ataaagctat cccaccaata agcaaagtaa gtaaaaattt tttgaaatgt
     5521 gtcattgttt tttctcctct tttatgtgac ttagagaggt tagtaataaa tttccagctg
     5581 cctctttcat cttaagcata gtccttgact agcacttttt aaaacaatag gccttaattg
     5641 aaaacaacta tcactatcag cgtttccaaa attcatcagt tctacaaaca aaaatattca
     5701 gcaaggatta ctttttcgat tcatcagtta aaaagtacct tttttcgaaa aactatgcta
     5761 tacttttaat tcgttattta cggcggaagg agcaaacatg cgatgaatga gaaacaacta
     5821 gaacaaacgc acgtggatga aacgatcgaa ctaatccaga tcgaacaaaa tatgctggat
     5881 acaaaacaac aagaattgac tcaggaaatg aatcattcga caaaagacac agctaatcac
     5941 aagattcgag ctggttccaa tgaagctttt tatgaatctg ctgttgaata tcgccaacat
     6001 gagcaggaat tgcttttgaa ataccatact cttgaagcac agcaaaaacg cctgcaaacg
     6061 ttgtctgtca tgaaagatag tccttatttt gcccgtatcg actttaaaga agaccgtgaa
     6121 acagaaacat tatatctagg tatcgcttct ttaagagatc tggcagaaga aacaatcgtt
     6181 attgactggc gcgcaccaat tgccaatctt tattatgaag gtgagattgg tcccgcattt
     6241 tatgaaactg aaacagatag aatagatgtc gatctgcagt tgaaacgaca atttaaaatc
     6301 caagaaggac gtattttatc tatggtagat acgtcggaag taatcaatga tgactttttg
     6361 ctagagatat tggatgaatc atcaagcaac catatgaaaa acatcgtctc tacgatacaa
     6421 aaagcacaaa atgcaatcat tcgggacaca acaagtaaag taatgctgat tgaaggaatc
     6481 gccggaagtg gaaagacatc cgctttgctt caacgtattg cttttctgtt gtatcataat
     6541 cgcaagtggc tcgaggctga aaacgttctt ctattttcac ccaaccattt gttttctgat
     6601 tacatctcga ctgtattgcc ttcattaggt gaaagcggcg tgcctacaca gacattcaaa
     6661 aattatttgg tgcagctgct gccagagttt tctttactag atgaacagca acaagaaagt
     6721 ggttttttgc taggggaaaa agatccgata caagtgatga aaagcggatt gaccttagtc
     6781 gatcagattg atcgctatat ccaaggcatc acaaactacg gtcccttgtt ccgtgatatg
     6841 aaaataaatg gccgtacgat cctatcaaag gaatcgattc gccaatggta taaagaaaca
     6901 aatgaacaat tacctttaca tcatagactt tctctattac aaacgaagct cctgaaaaaa
     6961 ttaggcggtc tgcaaaaaga cgaaacacgt cagcaatggg tcaaagatct ggcggaagaa
     7021 cagctccaag aactatacgc aacagatcca aatcttgaat atacagaaca aaaggagcgt
     7081 tcattacgta aaaaactggc caaccaaatc gtacgtaaaa gattccgtcg aatccatcga
     7141 gggatcatga attatcaatt tgtcaatata acgaaacaat atctccactt tctacaaact
     7201 gtgccacttt ctcttctaac acgacataaa atcagcgaga ccaggtggca ggaacatttg
     7261 acaactgttc gtacacactt gcgtcaaaga gaattgcgtc aagaggatgc tgtactattc
     7321 tttttactga tgcgccgaac atatccagtg acggttacac acaaagctcg ctatatcttt
     7381 attgatgaaa tgcaggattt cgcaccatca caagtggcat tgctgcaagc cttgttccca
     7441 aaagcaaatt tgactttctg tggagatcta aatcaaaatg tctttggaaa tgaaacgatc
     7501 gttggatcat tggaagacct tttcgtggac cgtgaagtca ctcgtttcca attaacgaca
     7561 agctatcgct ccacaaaaga aatcactgat tttgctaatc attttattgt gaaagaacat
     7621 caagtagaaa caacagcaag aaaaggagac cttcctttgc tcatccaagg aacaacagat
     7681 gatatcaaat tgaattggtt agcagatacc attcgaacga ctcagggaaa agcccggtat
     7741 tggcgtacag caatcatagc taaaacacaa gaagaatgcg aagctcttta tgctcaactg
     7801 ccagacgagt tgaaacaaca agtccagctg attttaaatg agagtgactt tatgaagcgt
     7861 tccattattt tacttccagc ctttttagca aaaggtctgg agtttgaccg agttttcttg
     7921 tgggatgtag atgcagaaca tttttcttct cagcaagaca aattgatcct ttacaccatg
     7981 tgtacacgtg cgatgcatga attgaccctt tttacctcca ataatgaaag tcctttgtta
     8041 aacaatatgg atatttcatc ttatgagaaa aaagtactgt aagtaaaaag acaactgcta
     8101 tcattaatgt tagcagttgt ctttttattt acaataataa ttgcagaaaa agtaattcaa
     8161 tcatttaagg tcatttattc tatatataaa tccaaatctg tttcaggata ttttaatttg
     8221 acaagcgaaa taatcatttt cagttcttcc atgttttctg gatattctgg gtcaaatacc
     8281 ttgctatgac ggccaatccc gccattgtcg atcaatcggt aaattcgatt ccattcaatg
     8341 aattggtcaa ttgattggaa attgctgatt ggatagccgc cacaatccaa aatctctgat
     8401 acacgaaatg ctaggtatgc actatcgatc actttatttt ttttcgtgtc tatcttctca
     8461 tttctttcga taagaatttt ttcaggacga tgtttcaagc tccactctaa tagtagaaag
     8521 aaagcctcca tccgatactc ttcttcaaat aaccgaaagg ctgaatcaga acgacgaaaa
     8581 agcagcggaa tcagataatt ttgtctataa atcagcattg gtgcgcggtc caccatacac
     8641 tctaaataac ggttcagata ccctgtaccg acatagtttc ctaatcgata gccttcaacg
     8701 ccgaatcttg cgtatttttg cgctaatttt gaacaatcag ttacgttcac agctaactct
     8761 tctactttgc ggtaaccgct taagatacgt tcaaaaggtt ctaaagtgat ttttgcttcc
     8821 atattcttcc ccgtccatct tccacatact tcatatcatt tcacatgata cttatgctct
     8881 catcatacca caggttgaat tagaaaagaa aataaatcac acaaaaaagc aagacaatct
     8941 gttagtgaga ttgtcttgct tttcgaaaaa gactgaatac ttttcgttaa aactggttgc
     9001 ttagtcttct aatgccacat tatggaacac atgctgtaca tcttctagat cttccagtgc
     9061 atcaatcatt ttttcaaatg tttcttgatc ttctggagat agtgttacct cgttttgagg
     9121 gatcatttgg atctcagcga ttgaaaaatc agtgattcct ttttctttta atgcttcttg
     9181 tatactatgg aaatccgcta cttcaccgta aacgatgatt tgtccttctt cttccattac
     9241 atcgcgaaca tcgatgtctt tttccattag gtattcaagg atctcgtcag cgtcttctcc
     9301 tgcaaaagca aagattgctg tattgtcaaa catgtaagaa accgctccgg aaacacccat
     9361 gttcccgcca tttttcccaa atgctgcccg tacgtctgct gctgttcgat tcacattgtt
     9421 cgtcaatgta tcaacaatca ccattgagcc gcttggtcca aatccttcat agcgcaattc
     9481 agagtatgtt tcatctcctg caccttttgc tttttcgatt gctcggtcaa taatatgttt
     9541 tggtacatta taagttttag cgcgatcaat gacgaaacgt agtttttggt ttgcatgcgg
     9601 atcaggatca cctgattttg ctgccgcgta gatttcaatc ccaaattttg cataaatccg
     9661 gctattatta gcatctttag cagttttctt tgctacgata tttgcccatt tacgtcccat
     9721 attttcactt cgctttctga tttgatagtt tcataacgca aaaacgtcct gttccattat
     9781 acttgtgaat cacgattctg tgaagctttt tttctttctt ccttcattct tctcattttt
     9841 agtcaattat ctatactcgg attgggattt gcccgaaatt ctgttccgga atattgcctc
     9901 ccaattgata gatttgatca cttctaacta acagttccgc ttcttgtgcc tctttttttc
     9961 cgattcggga ataaatagaa atctcttttt tttcttttaa gaatcttctt ccagcatcgg
    10021 taaatccaag tagtcgaaga taatttttat tttgttggac aggaatctct tgctttttga
    10081 tattcagcaa gacataacaa gataatcgtt ggatccgtgt ccatgtatat ctttttgttt
    10141 ttacctttga cacaaaatcc tcaaaactat cagcagttgc agctgctgtt ttcatgcgcg
    10201 attctattcc ttcggtcatc tgatagatat ctgtcagttc cagcaaagta gaagataaca
    10261 accgataacg caaatacggc caataagatt cccaagtctg cagcgaacaa gttgaaagat
    10321 cttcttctgt ctgaggcggc acaagtccag ctattctttt tccttcttct aacgcatggc
    10381 gaatggctgt tgcactggct atcctctgat ctgtgatgat tttttcatga tagcctgcac
    10441 ttttacgtcg gatcggatgt aattccatag ggtggacata cttggcattt tcctttgcat
    10501 aacttaatcc caagatatga tttggcgaag aaaaatcaag cgtaatatcg ggatacagac
    10561 tgcgaaaaac ctcagtcatt ttttgcggat aactatacgt ttgatcagac agttcttgaa
    10621 atgcctcttc tatcctatct tgattctctt ggacaaagcg tccgaaactg ctgtaatcaa
    10681 acgaagtctc ttcttctgtt ccaaaacaca aactgtcaca gtccagtgtt tgcaagattt
    10741 ttactgcacc tttagcaaaa tagtcagctg actgaaccgc ccattcgacg ggaagctcca
    10801 ctactaaatc cacaccattt tgtaaagctt cattcgcgcg atgccattta tcgatgatag
    10861 ccggttcgcc tctttgcaaa aaattcccgc tcattacagc aatgacgacc tctgctcctg
    10921 ttatttttcg tgccatttcc acatgatagc gatgtccatt gtgaaaagga ttgtactcta
    10981 cgataatccc gcagcttttc atgcgcatcc tccttcatag ttatcgataa aaaagaaata
    11041 gagacaagta aaaaaaggca aaaatcggaa aaaatacccg aactatataa actattctcg
    11101 caaacacaat acttctgcga cgaaaagctg cactgcaaga gcaatgccta tatcgttcgg
    11161 atatataatt tatgttgaag atttattctt ttcttgttaa ctcgagcagg caaaaccgct
    11221 agtctttgta tgctacaaag aaccagcgct ttgatttctc tgatgctgct tcgtctgtaa
    11281 aatcagaaaa tgcttcgact ttcgaaaagc cgctgttttc cagcattctt aaataacttt
    11341 ccaatggata ggtacgctct tgatgtagtt catcttcacg aataaatcga ccagaccctt
    11401 cttgttcttc aacgaaaaag gtaagaaaat gttcgatgct gtgtttctcg cttcctggat
    11461 aactatccca caaaaaagca aaattatccc cttgataatg atagctatat tctggaaaaa
    11521 cctcatctac ttgataggtg gagtgtacgt caaataaaaa tcggccattt tcttctaacg
    11581 cttgatagac ttcatcaaac acttgctgta cctcttgtct atttttcata tagcacagcg
    11641 aatcagaaaa acaggtaatt gcctgatatt gtccgatttc tgataaatcg agcatattgc
    11701 cttccacaaa ttggatcgat gcgtcttctt catatgctcg ctggctggca atcatcaaca
    11761 tctcttctga aaggtctaac cctgtcactt tatatccatc ttttgcaaag gcaaccgcta
    11821 atgctccagt accgcatgcc agttccaaaa tattttttgt gtcttcttgt aaatgacgtt
    11881 tcgaaaaagc taaccattgc tgataaagtg tttcgtccat cacttcatcg taaatgaaag
    11941 caaatgtttc ataagccata tgttaatcca accattcact aagatcgact agcggagcat
    12001 ctgaccatag tttttccaga ttatagaaat ttcgttctgg cgcatggaaa acatgtacga
    12061 tcacatctcc aagatcgatc aatacccatt ttccgccttc ttttccttca atacgtttta
    12121 cttcatattt gttttcttct tctttatcaa tgatttcttc tgtaattgcg ttgatttgac
    12181 gttcgctatt tgctgaacag atcatgaaat aatctgccaa caaggaaaca tttcgaacgt
    12241 ctaaagcgat aatgtcttct gcccgttttg aatctgctgc ttcaatcgca atttttaatt
    12301 gttctttact atctatgatg atttcctcct aatatgagca gcttattttt ttgctaccca
    12361 gtaattatat gtttcgattg tttttggata aatctgttgt tcttgcgcaa gcaaatgggc
    12421 caatgtatgt tttgtttcaa atgctacagc ttcgtctaga tcagcccatg caatggctcg
    12481 tgcatcttgt accccaggaa aatctcgacc tggttcaata tagtctgcta cataaatgat
    12541 tttgtcaagg agactcatct tagcagcccc agtcgtatgc acccggattg catgaagaat
    12601 ctctgcatcg gtgattccta attcccgctc tacaaacgaa gcgccaacaa gaccatgcca
    12661 gattgcatta ttataattca ataactccgg atcaaaaccg tctcttacga ttaccatttt
    12721 gaactcctca tctggtcgtt cttttgcata atcatgtgtc aatgcagcaa tactagcttt
    12781 ttcaggagaa gcaccgtatt ttttggcaag agccacggct gtttcttcta ctccaagcac
    12841 atgcttgaag cgttgttcgc tcattctcat ctgtattttt tgcatcaggt tttctctaga
    12901 ataagcagta tattcattac tatagtccat attcatacaa cccttcattt tgaatataat
    12961 caattacttt atctggaaca aggtagcgga tagaacagcc ttctttgatc ttttgacgta
    13021 ttttcgtgga actgatgtcg atctcaggta catctaccca aattacagga tatggagtat
    13081 ccgttgtgta tcctggtcga cgtataccca caaagttgac catagaagtc agctcatcga
    13141 ttttatacca ttttggcaaa tattctacca tatccccacc gataataaag taataatctg
    13201 tatccggatt gttttgcgtc aattccttca tagtatcata ggtgtaactt ttcccaccac
    13261 gagctaattc aatcgtttca atctgcaaaa aaggattgtc ttccaccgct aattccaaca
    13321 tgttgagtcg atgttttgca tcaatcgtct gtttctcatc aacatgaggt ggctgataag
    13381 aaggcatcaa aaatacgcgg tcaagaccta aattccggcc agcttgttca gccatcacta
    13441 aatgtgcaag gtgaacggga ttgaatgttc cgcccaagat ccctacttgc tttttcttct
    13501 ctaagaattg aggcatttct tcaggaaata attgtgaacg aacaaatgtc ttagcttgcg
    13561 tattcatcat ggtcactcct tatattgctt ttacttcttt tgatagcctt tgatactttt
    13621 cttttgtgga aggtttgtat aatacaataa cacgtccaat gatttggacg atttcgcaat
    13681 ctatttcttt ttctaatact tgagctgctt cttctgcaat ctcatctgta ttttgaagta
    13741 acgatacttt gatcagttct cttttttcta aagcttcttc aatttgaacg atcattgctg
    13801 aattgatccc accttttccg atttgaaaaa tcggctgaag atgatgcgct ttgctacgta
    13861 aaaaacgctt ttgttttcct cttaaactca taattttcct tcttccttaa atcaatgctt
    13921 tgcgtttcaa tacatctaca ccctttggcg cccagcccgc aattactact ggcgctgtta
    13981 cagtgatcca gcctagaccg gcaaaaacga tgtctgtttt ttctttcaca gaaaactcaa
    14041 aacgaacaag ctccggaaat gcctcgactt catcaggacg aggaggctgt aataatccac
    14101 ctacatgttt ttgataaaat tcgtctgctt tttccagttt cgttcgatga atatttacat
    14161 catttgacac ataagcaata aatgaagcac gattgccgct gataaaatca aatcttgcaa
    14221 gtccgcccaa gaaaagtgtt tgcccttcat tcagctgata aactttaggt ttgatttctt
    14281 ttaacggtgc aatgatccgc aaatcttttt tacctaagta gtgcgccatt tgatggcgat
    14341 ggataattcc cggtgtatca atcaaaaaat gcccgtcatc taaaggaatc tcgattttat
    14401 ccaaggtcgt tcctggaaac tgcgaagttg tgattacatc ttgtactccc gctgtatttt
    14461 tgatgatttg attgataagc gtcgattttc cgacatttgt tactccgacg atatagacat
    14521 cccgtccatc gcggtattct tcgatttttt ctaatagttc cgtcatctca tgagatttct
    14581 tagcactagt taataataca tctactggac gaattcctgc ttcgtaagca cgttccttca
    14641 tccattgtgt taatttagtt tttttcaatg atttaggtaa tatatccact ttgttcccaa
    14701 ctaaaagtac tggattgtca ccgacaaaac ggtgtagtcc tgggattagt gaaccattga
    14761 agtcaaaaat atccaccaca ttgacgatca atgcatcttt ttgccctaat tcattcagta
    14821 agcgcaaaaa gtcgtcatcc gtcaatgaga catcttgggt ctcattataa tggcgtaatc
    14881 tgaaacaacg ctgacaatag acttccccgg aagctaaacc tttttccaaa gccgtttgcg
    14941 gcgtgtatcc taattcaccg ggtttgtttg tttgtataac ggcaccacag ccgatacatt
    15001 gtaattcttc tgtcattcga ttccacctcg ccagcccata tcagggtgtt ttgctaatag
    15061 ataggccata attctttttt cccaaaaacg attaaattgt gtcttccaac tatctgttgc
    15121 gataatgggt tttacaagga tgctacgtat ccctgcacga ttggctccac gtatatcagt
    15181 cataatctga tcgcctacca ttactatctc atcatctgct aaatccaatt gtttctttgc
    15241 tatgttgatc cctcttgcta aaggtttcat tgctcgtgca acatacaaaa gatcaaattt
    15301 ttcaatcgct cgcgcgacac gttttgaatt attgtttgaa acaacaacaa cagggattcc
    15361 tgcatttttc atttctaaaa tccaagtaag caactcttct gttccatctg gattattcca
    15421 tgcaatcaac gtattgtcta aatcggtcaa tactgctttg atgcctagat tctttaattg
    15481 ggcaggtgta atctgataga tggcttctac catccatgtt ggtttgtaat ttgaaaacat
    15541 gctgtctcct catctgcaaa aaatgaagga gcacataaag tactcctcaa ccccgtatta
    15601 tactgcatat cagcaaaaaa aactacctct atactcgttc gtctttcaga aaaagcattt
    15661 ctttacaaaa tgaccaaaaa taaagattga tcacagaaaa atttagaaac aaaaaacaac
    15721 taatattggc ggaacctctt gtatcgtttt tccagtaatt tatgctgatc taatcgaaca
    15781 agttccgtca atctttcaat caacgctttt ttcataatgt gtgcgacttt atatcgtggc
    15841 aactgctcgc cgttgaacgt ttcaggaata actcgatcaa cgattcctaa ctcgcgtagt
    15901 tctggcgcag taattttcat caactcagct gcttctgcgg cgcgactacc gtctttccac
    15961 aaaatcgacg caaatccttc tggagaaagc acagcataaa tcgtttcttc cagcatccag
    16021 acttcatccg ctaaacctag agcaagggca ccgccacttc caccttcacc aatgatgatg
    16081 gcgatgatcg gtacctttaa atcagacatt tcgagcagat ttctggcaat agcctctcct
    16141 tcgccgcgct cttctgctcc tacaccgcaa tatgcacctg ctgtattgat caaggtaatc
    16201 accggtctat tgaacttttc cgcttgtttc atcagtcgta aagcttttcg atagccttca
    16261 ggatggggag aaccaaaatt tctgcggata ttttcctgca gatcccgtcc tttttgaata
    16321 ccgatcactg ttaccggttt gccatctaat cgagcgattc caccaacaat cgcttcgtca
    16381 tctgcaaata aacgatcacc atggcattcc tcgaaagaat cgaagatctc ttcaaaaaaa
    16441 tccaagcttg tccatcgttc tttagctctt gctaactgaa cgacatcatg tgctgtctta
    16501 tccacgatct atccatcctt tctgtgtatg caattcaaga agcgtatgga ttttctgttt
    16561 caattccatg cggggaacaa tctgatcgac aaaaccatga gataataaga attcagcctt
    16621 ttggaaatct tctggaagtt cctgcttgat cgtctgttcg atgacgcgtc ttccagcaaa
    16681 accgatcaag ctttggggtt ctgctagaat aatatcgcct tccattgcaa aactggcagt
    16741 tactcctccg gtcgtcgggt ccgttaaaac agttagataa aaaagacctt cattgctatg
    16801 ccgtttgaca gcagcagaga tttttgccat ctgcattaga gaaaagattc cttcttgcat
    16861 ccgtgcgcca cctgaagctg tgaacaagac gactggaaga ctttcctttg ttgctcgttc
    16921 gaataatctg gtgatctttt ctccgacaat cgttcccata cttcccatga taaaattagg
    16981 atccatcact ccaataatga agggaatccc ctgaatggtt gctttaccag tgaggactgc
    17041 ttcatgaagt cctgttttat cttgcatttt tttaattttt tccgtatatt cgggaaatgc
    17101 tagcggatct ttggttacaa gatccgtatc ccattcttca aaactttttt catcaataat
    17161 caaagctaga cgctgccatg caccgattcg aaaagcgtat ccgcaatgag ggcatacttt
    17221 ttcttcaccg atgtctttcg tataaaggat atgtttgcaa tttggacact ttgcccacat
    17281 gttatcagga acagatggcg agttagcagg tttgctctct ctattaggat tgatccgaat
    17341 atatttcttt ttcttaaaca gagccatcta tgcgcctcct atctccgttt ctggtgtcca
    17401 attcggtaaa aattcttctt gtaaaaatgc tgtgctgtaa tcacctgcta tgactgcagg
    17461 atgactaatc aaatccatct gaaattctgc gttcgtgatg attccttctg tgataaattc
    17521 acttaaggct cgctgcatct tcattaatgc ttcaaaacgc gtatttccat ggacgattat
    17581 ttttgcaatc attgaatcat aatatggcgg gatcgtatat cccgggtaaa ctgcactgtc
    17641 tactcgcagt cccatcccac ctgctggaag cagtaagttt tggatcttcc ctggagaagg
    17701 agcaaaatgg aaagcaggat tttctgcatt aatccggcat tcgattgcgt gtccttggaa
    17761 tactacttct tcttgacaca cattcaaagg ctcaccggct gctatctcca cctgtttttt
    17821 tactaaatcg attcctgtga ccatttctgt tactggatgt tccacttgga ttcgagtatt
    17881 catttccatg aaataaaaat cgccttcttc atccatcaga aactcgatcg ttccggcatt
    17941 ttcataattg actgctttag ctgctcgaac agcagcgtct cctagtgctt ctctttttgt
    18001 ttgtgagatc actacagaag gagattcttc cagtactttt tgattgttgc gttgtaaaga
    18061 acaatctcgc tcgcctaaat gaatgacatg accaaatcga tcacctaaga tctgaacttc
    18121 tatatggcga gcaggataaa tgattttttc caaatacata tcatcatttc caaatgccgc
    18181 tgctgcttct tgctgagctg aagaaaaatg ctgtgggagc tcttcttttg attgaacttt
    18241 ccgaatgcct ttcccgccac cacctgcagc tgctttcagc atcactggat aaccaattct
    18301 gtctgctatt tccaatgctt cttctactgt agataataca ccagtacttc ctggaatgac
    18361 tgggacattt gcttcttgca tcaattgacg cgcattgatc ttatttccca ttgcatcgat
    18421 cgttgcactt ttaggaccaa taaatgtgat attgcactct tcacacatgg aggcaaatcg
    18481 gctattttca gataaaaaac caaatcctgg atgaattgct tcggcttttg tcacgattgc
    18541 agcgctcagt acttcctgaa cattcagata tgaatcaacg gcttttgccg ggccaatgca
    18601 gattgcttca tctgctaact gtgtatgaag tgcttcggca tctgcttctg aatatatcgc
    18661 tacggtttgg atccctagtt cgcggcatgc acgaatgata cgtacagcga tttcaccgcg
    18721 gttagctatc aatactttag aaaacatatt tcacctatcc aatcataaag gttaattccg
    18781 cttcggctac ttttttaccg tctactttag cgattccttt gcctattccg gctgaagctt
    18841 tcactttcaa tatctcaact tcaaggtata aggtatctcc cggtgtaact ttcttacgga
    18901 attttgcttt gtccaatccg ccgaaataag ccgtctttcc cttgaattgt tcaagagaaa
    18961 gtaatgcaac tgctcctgct tgagccattg cttcaacaat caatacccct ggcataacag
    19021 gttcttctgg aaaatgtcct tgaaaaaagg gctcattgat cgttacattt ttcttagcaa
    19081 cgatccgttc tccttcaacc atttcttcca ctcgatcaat caaaagcatt ggataacgat
    19141 gtggaatgat ttcttttatt tcttgtatgt tcattgtttt ccctctttcc tgctttgctt
    19201 atttttgctg aatcctaaag agtggctgtc catattcgac aactgactcg ttttctacaa
    19261 ggatttctgt gatcactccg tcggcctcac tagttatctc attcatcagt ttcatcgctt
    19321 caataatgca gataacttct cctttggcaa cttgatcacc tacttttttg aaagctggtt
    19381 tgtcgggcgc tggttgcaga taaacgattc ccacgattgg cgaaacaacc tcgattccat
    19441 caaatactgc cgattctttt tctttcatta tttctggagc agttgttgct tgttcaggta
    19501 tgacattgac tggctccgaa actggcaacg tttcgtttgt ttgaaccata ttcatgcctc
    19561 gacttgtttt atttttattc atatacaatt caaattgacc ttcacgcaaa tcgaattccg
    19621 ttagcgagga ttgatcaaat tgactgacta attctctgat ttcattgata tccaaaatta
    19681 ttcctcccag cgtttcatgc acagaaccgc attatgtccg ccaaacccta atgaattact
    19741 cattgcataa gtaaaacttg caggtttgct ttcgtttttg acaactgtca agtcaatctc
    19801 aggatcttgt ttttctacat tgatcgtagg tgggataaat tgatgttcta atgccagcaa
    19861 agttgccaag gcttcgatcc cgccggctgc tcccaataaa tgtccagtca tcgatttcgt
    19921 gctgctgacg taagtatctc tgaaattttc acctaatgcg atttggattg cttttgcttc
    19981 tgcctggtca ttggctggtg tacttgttcc gtgagcattg atatatccga cttgttccgg
    20041 ctgtacacca gcttcttcca tcgcaagctt cattgcttta gatgcaccag aaccatctgg
    20101 agtaggagct gtcatatggt aagcgtcaca gtttgcaccg tatccaacga tttctccata
    20161 gattttggca ccgcgagctt gtgcatgttc taaagattca agaactagaa cgcctgctcc
    20221 ttcacccatc acaaaaccat tccgattttc gtcaaacgga atcgaaccac gattaggatc
    20281 agttgattct gagagtgctg ttaaagctgc aaatccagca atccccatct cacaaatcgt
    20341 tgcttctgtt cctccagcaa gaatgacatc agaatagcca tgtttgatgt tacggaatgc
    20401 ttccccaatt gaattcgttc cgctagcaca agctgttacg atagctgtac aaataccttt
    20461 tgcacctaca cgcaaagcaa tatttccagc tgccatgttg gcaatcgcca ttggtacgaa
    20521 cattggagaa actcgttttg cacctttttc atgtagacga ataacttggt tttcgattgt
    20581 tggaagacca ccgatcccag atccgatgat gacgccaaac cggtcttgat tcattttttc
    20641 tttatctaaa ccgctcatct ccattgcttc taaagcagcg tagattccat agatcgaaaa
    20701 catatccatt cgtttgctat cttttttaat aaaatattta tcgtaaggga aatctttgac
    20761 ttcacccgct aaggtaatcc ctgtttctga agcatcaaat ttagtgatcg gtgcgatgcc
    20821 attcgtcccc tcttttaagc tattcaaaaa gctgtctgcg tcatttccaa taggtgaagt
    20881 gactccatag ccagtaatta ccactcgatt catttgtttg ctctcctttt cttatccgtg
    20941 catgaccaat ccgccatcga cattgatgac ttgtccggtg atatatggat tttgtgctaa
    21001 gaaaactgct gtttgtgcaa tatcttctac ttgtccgaaa cgctgcatcg gaatttgctt
    21061 ttccgcttgt tccttgactt tgtctgctaa aacttccgtc atatcagttg tgatgaatcc
    21121 tggcgcaatg gcattacatg taatgcctct agttgcagct tctcgtgcca cagattttgt
    21181 taatcctact acgccagctt tactagctgc ataatttgct tgaccaatat ttccaatcaa
    21241 cccagataca ctagagagat taatgatggc cccttctcgc tgcttcatca tttttttcaa
    21301 tacgtgctgc gtcatattga aggttccaat caaattgata tccagacatt ttttgaaatc
    21361 ttctgcatcc attcgcatca caagtttgtc atttgtgatt ccggcattgt ttactaacac
    21421 atggatcgat ccaagctttt cttctgcttc tttgatcatt tgtcccgctt tctcataatc
    21481 agagatgtca ccggaaactc ctacgcattt tacaccgaat gcttcgattt cttctatctt
    21541 ttcttttgga atctctccgc gaccattcaa aatgatattt gctccagctt ttgcaaaagc
    21601 taaggccatc gctttgccga ttcctcttgt actacctgtg ataaatacat tttttccttt
    21661 tacatccata acgttcctcc ttatagtatt gctattgttt catcaaatgt ctgcttattc
    21721 tcaacacgca gaactggtat tgttttatcg atttttttca taaatccgct taatactttt
    21781 ccggggccga cttcgatgac ttgttcgatg ccgattgttt ttaacttatg gatactctca
    21841 tagaaacgaa caggttgcat gacttgctgt tcaagtagtc ccgcgattgt ttctttcttc
    21901 attatttccg ttgttgtgtt gcttatgata ggaaaagaag gttcagagaa ttgaatctga
    21961 cttaggtcct tcgccagttt ttttgctgcc ggttctaaaa tagctgtatg aaaaggcccg
    22021 ctgacattta gagggatcat tcttttgaac cctttttctt ttaatagtaa aacagcttcg
    22081 tctactgctt tttcttcgcc accaatcacg atctgctgag gtgtattata atttgcagga
    22141 gatacgatgc cgtacttgct agcttcatga cagctttcct cgatcgtttc aatcggcgca
    22201 ttcatcactg caaccatttt cccgcttcca gctggggcag cttctgtcat ataagcgcct
    22261 ctttttgcta ctaacgcaac tgcttcagtg aaggatagcg cattactagc tactaatgcc
    22321 gaatattctc ctaaactcag tcctaaagct gcatctggga tgattccatg ctccttcaat
    22381 aagcgataat acgcgatgct gactgttaga atagctggct gtgtatattg cgtctgatcc
    22441 aaacgttcat tttctgtaaa gcaaagttca gccatatcgt agccgagaat ctcacttgct
    22501 tcatcaaatg tctgctttac aacggcttct tcatataaat cttttcccat accttgatat
    22561 tgtgcacctt ggccactaaa taagaatgct gttttcatgt ttttctccaa tatatccaga
    22621 atatatgttt gattcttcct attcaaaaag gccgagacat tcctatttca ggaaatgtcc
    22681 cagcccccaa cctaatttta atgattatgc agtttgtttt tctacgtaag tcactaaatc
    22741 ttgaaccgtt ttgattccgt cttctgtttc gattttcacg tcaaattcat cttcaatttc
    22801 attgatgatt tggaataaat ccaagctgtc agcttctaag tcttcttgga tgtcagtagt
    22861 caatttgatt tcttcagttt cttttcctaa ttcttctgcg atgatttctt gaattttttc
    22921 gaataccata ataatatatt cctccgatat tgtttgcttt ttatttttat aatttaacag
    22981 tctacaactc catgagaata cttccccatg ttaaacctcc gccatagcct gtaaatatta
    23041 ctttctgctg ttttcctaag gtgatctttc cactagaaac tgcttcatcc aataagatag
    23101 ggatgcttgc agcagatgta ttcccatatt tatccatatt ggtcaggaac ttttcttgcg
    23161 gcatctttac ttttcgggca attttctcaa taattctgag gtttgcctga tgcaaaagca
    23221 gataatcaac tggtttgtct ttcatgactt cttggatatt gtttgcaacg tctcgtacgg
    23281 caaaatcaaa aatatctctg ccagtcattt gcaaataata cgaaccttct gaatcttctg
    23341 aatagaacgg atttttattt tgctggtagc cagcggtcaa tgagctactt ctggtaccgt
    23401 cagctgctaa tttttctttc agcaattttt tctgtggatt cgcttctaag agaatcccac
    23461 ctgctccatc gccaaacaac acagcagtcg tacgatcaga ccaatcgatt agcttagata
    23521 gtgtttcacc accaatcacc agtcccttag ttgagccgca gcggatcatt ttttcagcca
    23581 tgcttaacgc ataaacaaat cctgagcacg cagcactgat atcaaaagcg atagcatgag
    23641 ttgctcccaa tttcccttgt acttgtgctg ctacagatgg tgtcgtgtaa tcgggcgaca
    23701 ttgttgctac taaaataaaa tccaaatctt tagggtttag atttttctgt tttatcaatt
    23761 tttccgccac taaaatgcat aaatcagaag tctcctgatt tgttacacat cttcgttcac
    23821 gaatacccgt ccttgacgaa atccattcat cagaggtatc catcatcttg gaaagatcat
    23881 tattagtaat aatcttttca ggaaggacgc tggctgttgc agtaatcatt ccaaattgtt
    23941 ccattaaata tcctcactta tagtcttgca agaagtcgtg caagtttttc agtgcatcca
    24001 gcaaggcatg ctgttcctcc gtagccattc cgtctaagat gttcttgacc atttcacgat
    24061 gaaaatgctg atggacccga aatagtaact ttcctttttt cgttagtccc aactttacaa
    24121 cgcggcggtc atcttcactg cggatacgtt cgacatagcc tttttttact aacttgttaa
    24181 tagcagtggt caaggtccca acagtaattg atagttcttt ggctacttct gaagttgttt
    24241 ttttcttgta catcccgatt gcctcgatcg tgtgcatctc tgtgattgac agatctttga
    24301 attgagattt tttcagctca gactcttcga ttgtcaaaat atcattgaag acactaacaa
    24361 gataatcatt tactgttttt aaatctggtt ccatgttcca ccgtccacta attagtttga
    24421 ttatcaaatc ttttgatgtt caaactatat cttaactttt ttcaaaatgc aaccttaaaa
    24481 gatcattttt ttactatatg agcttttttt aagattttac tcatttaaaa caactgataa
    24541 atcagcattt ataatttctt ttattagaaa aatcatctat ctcacatatt ttgattatca
    24601 aagtattttc tgtgaacaga actatagaat tccctaaaac ttgtccatta tttcaaaatt
    24661 tgttatagtc tttttattca aagcgtaaaa ggagatccta tgttaaaaga aaaaatgaaa
    24721 actctcccca tgctgccggg tgtctatctt atgaaagacc gagatggtaa ggtcatctat
    24781 gttggtaaag caaaacggct caaaaataga gtaagcagct attttcatca gaataaacag
    24841 cattcaaaaa aagtattacg tatgattcat catataacag attttgattt cgtcgtagta
    24901 gacacggaat tagatgcttt attgctcgag tgtcaattga tccaacatta ccgtcctttt
    24961 tataaccgac aaatgaatta tttcagtaat tataattatg tacatattac caataaggga
    25021 tttgtattaa cagatactcc tacggctcga acatacgggc cttttcgtct ctataaaaaa
    25081 atgccgtcta ttttgcgtat aatggaagaa acttatcaaa tgccttggtt gtctgaaatt
    25141 agtttgttag ctttgcgagt ccagcttcct gacctacagg aaatgacttt tgaacagaaa
    25201 aaaaaggaac tccaagggct gtttcaaggc cgaaataaaa agctactgac ttacttgaaa
    25261 aaaagacaac aacatttcat ctatcagttg aatttcgaaa aagccggtat gcttcaaaaa
    25321 gatatcgaat tagttactta ttttattaga cggatccagg aacaaaagca gtttttaaga
    25381 acaccatcgc tcaccttcag catgccatta gcagcagatg agagtcagaa aaagcactac
    25441 ctcgtttgtt atggtcaact tgcagaaaca atgattacct ctggtgacgt ttctcctgac
    25501 ttctattatg aaaagaaaga agctcattta tctttgaaac gtcaattgtc aaaagaagaa
    25561 atcgatcctg tacaaatctt gatcagttac cgcaaaaaat tagaaaaaga acagtttgaa
    25621 attgaactgt taaacaaaaa agaagctgaa aagcaactaa attagttgct tctcggcttc
    25681 ttttaggcat cttcaacttc aaatgtcaat tatcctaaaa tttattggat taagtcatag
    25741 atttccatcg ctacgatatc gatattatca aattcgtatt gctgatgagt atctgtttca
    25801 gttaattcaa atgtatcggt cgctttatca taagttactg tacacttctc tacgccttct
    25861 ttttcaaaac ggcgaacttg cagttcatta tctgctgact cgaccatagc ctccagtcgt
    25921 tttatgattg cgactaattg tgaatgtgtc atcggaggtc ctccttttct tatttctgtt
    25981 atattgtatc aaaagcatag cctacttgca ttgattttct ctaaaaaaac tcgtttttta
    26041 tgattttttt tctggtattt ttccttcagg ccaccaaagt ttgatcaaag cttgggttcc
    26101 gtcattctca aaacctttat ctgccaactc ttcatatagt ttcaatgctt gggtagttgc
    26161 tggcaataca agatccattt tttctgcttc ttctaatgca atctttaaat ctttgataaa
    26221 atgtttgaca aaaaaaccag gtgtgtaatc ttcttttaaa atacgaggag aataattgct
    26281 taaagaccag ttagctgcac ttccacctga aagcgtctca atcactttct ttaaatcaag
    26341 tccgtttttt tgtgcataga caagcatttc cgtcattcct gtcatcgtac ctgcaatcat
    26401 gatctgatta gccatttttg tatgctgacc tttcccagca gaaccatgca atgtaaatgt
    26461 cgtaccaaat tctttgaata aaggcagtac ttgatcataa acggcttctt ctccaccgac
    26521 catgatcgtc agtgtaccat tctttgctcc taagtcacca ccggataccg gtgcatctaa
    26581 cgcatctgcg cctttttctt ttgctgtttt tgcaattttt tctgccaggc ttggtgtact
    26641 tgtagtcaaa tcaactaaaa tatgtcctga gatatctgca gaaaaaatcc ccgactgtcc
    26701 atagtagatt tcttctacat ctttggggta acctaccatt gtaaagagaa tattactttg
    26761 ttctgctacc gcttttggtg tatctgccca gatagctcct tctgttacta aaggatcagc
    26821 ttttgctttt gtccgattat agacagctac ttcgtgtcct gcttctagta gatggcgtgc
    26881 gacagcactt cccatgacgc ctgttccgat aaaaccaagt ttcatttttt cgacctccta
    26941 aaaatcaaaa atccttgctt ctatgctagt atacgctaga aacaaggatt ttttcataaa
    27001 aaatgtttga attttatctt ttaaatgaat ttaattttat tttgattcgt tcaatcgagt
    27061 cttcttcttc ttttcttcgc atctcttctt catgataaac aaccatgtct tgataaaatt
    27121 cgatcatagc ttcgccgaaa tgtgtagatg aaatatcata aagtttagct tctaaaactt
    27181 ttggatcttt aggaacttca ctggaaatat aatcaataag tgctggtgca aagtcttcgt
    27241 cggtttcaaa agttttccct aatgaaggat gatcgaacaa tcggttcaaa taagcatttc
    27301 cttccacgac acaaggtgtt ccggctgcca tcgcttctgt ataagtaagc ccttgtgttt
    27361 ctgaagtaga agcactgaca aaataatctg ccgctttata ataaagtgct acatcattgt
    27421 tgtccacttc tcctgtgaac tgcacaaatt cttctaactg cagttctgag atcaattcct
    27481 ctaactcttc tacataaggt ccttttccta cgataactaa tctggcgtta ggataagcgg
    27541 agatgacctg aggaaaccca ttaatcaagg cttggatatt tttctcataa gaaatcctgc
    27601 ttaaagaaag aatcatcaaa tggttttcct gaagacctag tgactccctt aatttgctga
    27661 tatcctgctg agtgatatca gaacgtttga atttttcaat gtcgatacca gtaggaatca
    27721 cgcgaagcgg tgctattaca ccatagctgc gtaatgtatc aataacacgt tcacttggac
    27781 aaactacacc tgtcgtatga tttgcaaata atctagacaa gtattttaca tgggattgcc
    27841 tgatcacttt tcctttaccg atataatgaa ggtagtcttc atacatcgta tggtaagtat
    27901 ggatcagagg tattttcaac ttcttagcta ccatcttccc aagtatccct gctccgaatt
    27961 ctgtatgggt atgaataaga tctagttcta gttctttggc aaccaaataa gcataccaca
    28021 tgcctctaac aacaactctt cgatccttga aagaaataaa tggtacactt ggcattcgaa
    28081 tcacatcttt ttccaactta tccgcattag gatcggtcgt tgtaaaaata tagacttcat
    28141 gcccatgtct ttctaattct tgttttaatg ttttgatcga tgtagcaact ccgctgactt
    28201 gcggaaagta ggtatcggta aaaaagccga ttttcatgtt tttcgcctcc aaactagtcc
    28261 ttgacctgat ttactttttt taatttgcta gagacttttt cattcagtac actttcgtat
    28321 acatttttaa gttcttcacc gattttattg atacttcgct cttttgctgt ttgataaccg
    28381 gcttgtgtcg tactcggtag ttcttgattg gtaatctgtt ggatcagtcg gataaattct
    28441 tcgtttgtct tccccatata gcagttcttg ctatcttcta accagccatt atacactgga
    28501 atatctcgaa caagtacgtt ttgtttgctt gctaaagctt ctaaaacaac gatcccttct
    28561 gtctcttcat aagaagggaa aaagaataga tctgcacctg aatacgcacc ttctatgatc
    28621 tctccacgaa tgtaaccagg aaacaggaca ttttcaggat gatcttcttt tacaattttc
    28681 cggatgttcc gaggaatcga gtacatggga acatgaccaa accaaataaa tgtgtattcg
    28741 ggcatcttct tagcaatttc tacgaaatca atgattcctt tacgttcgaa aaacaaaccg
    28801 acacaaatga ttactttttg atccggagac agtttgaaat attctctgaa cttttgttct
    28861 ttcattggat cagggtgata tttctctaag tcgatcccat tggaaatagc ttgaatcggc
    28921 acacggatac catagctttc caacaactgt tttgaataag gtgttggcgt gatcagatag
    28981 tccgcttttt ggtacaatcc taccagatat ttttttacga taggagaaag ctggttcgat
    29041 ccgataaagg aatttcggaa atcttcctct gtagaatgcg catgatagac aacttttttt
    29101 ccttctcttc tggctttatt gaccatatta tgactattga ttccgtatgt attgatgtgc
    29161 aggatgtcat aatcttcttt ttcatctagt gtataagaga taccgacttc cgtcagagca
    29221 cgtttttgat gatcaagcgc acgcccgatt ccagattttg caagcatctt ttcactttca
    29281 aaatataata ataccttcac cttacgtccc ccttcactta tatagtataa catagcctac
    29341 aaactgtcac tcaaacttaa gccctatttt tgtctattct tactgacaaa aacgttttct
    29401 taaaaaagaa caaaaaaact ggcgtagctc ttttacaagc cacaccagct tttgatacgt
    29461 tgtttatttt acatattcat gaacaagttc aacgacttct tccatcgtat cgcattcttt
    29521 caatgcacga tcagcaagtt cagccatttt cgctgtgtcc aagcgtttca ttaaaccacg
    29581 cgttttaaga atagatgtcg cactcattga gaactcatct agacccatac ctactagcaa
    29641 tggaacagct gtttgatctc cagccatttc tccacacata cctgcccatt ttccttcagc
    29701 gtgtgctgca tcaattacat ttttgatcaa acgtaaaatt gatgggttat atggttggta
    29761 caagtaagaa acgcgttcgt tcatacggtc tgctgccatt gtgtattgaa tcaaatcgtt
    29821 cgtacctaca gagaagaaat ctacttcttt tgcaaacttg tctgctaaga ctgctgctgc
    29881 tggaatctcg atcatgatgc cgacttggat cgtatcagat acttccttgc cttcacttat
    29941 caatttttgt ttttcttctt caaagatcgc ttttgctgcg cggaattctt tgagtgtagc
    30001 taccataggg aacatgatac gtaaattacc atgaacagat gcacgaagca atgcacgcat
    30061 ttgtgtacgg aacatttcgt cgccttgttc agataaactg atacgcaatg cacgatatcc
    30121 taagaatgga ttcatttcat gaggtaattg cagatatggt agttctttat ctccaccgat
    30181 gtccattgta cgaacaacta caggttttcc ttccatacct tctaatacag ctttgtaagc
    30241 ttcatattgg tcatcttctg ttgggaagtc tggagaatcc atatacagga attcagtacg
    30301 gtacagacca actgcttctc caccattatt atggacacca actagatctt ttggtgttcc
    30361 gatgtttgca gctaattcaa aatgcttgcc gtcagctgtg acagtttctg cattttttaa
    30421 tttttcccat tctgcttttt gtgctgcgta atctgcacct gctttttcaa attcagcttt
    30481 ttgttcatct gtaggatcga tgattacatc gccttcgatc ccgttgacag ccaaaatatc
    30541 gccttctttg actttagcag taatttcttt tgtcccaacg attgctggaa tttctaaaga
    30601 acgtgccatg atagcagaat gtgaagtacg tccaccaatg tctgttacaa acgcttttac
    30661 aaaattgcga tctaattgtg ctgtatcact tggagtcaag tcatgtgcaa caacgaccac
    30721 ttcttcgttg atcattgatg gatttggtaa agtaacgcct aataagtgcg ctaaaatacg
    30781 tttagcaacg tcacgaatat ctgcagcacg ctcttgcata taagcattat cttccattgc
    30841 ttcgaacata ccgatataca tatccgttac ttcttttagc gctgattcag catttacgct
    30901 gttgtcttta atattttgct tgatttgacc taccatttct ggatctgaaa gaaccatcaa
    30961 atgggcatca aatacttgcg cttctgcttc acctaagctt tgcgctgctt tttcacgaat
    31021 ttgctgcaat tcttcagtag atttagctaa tgcagcatcc aaacgagctt cttcagccgc
    31081 agtatcttct actgttgcct tactgaatgt taaatccggt tgaactagca ggtaagcttt
    31141 tgcaacggct acaccgtcac tagcggcaat cccttttagc atttcaacca ttattcagat
    31201 aagccttctt tcttcattgt ttcaacgatt gctgccattg catcagcttc gtcagcacct
    31261 tctgcagtaa tagtaacatc agaaccttga cctacaccta aagacataac gcccatgatt
    31321 gatttcaagt ttactgattt acctttatac tctaagttta catcagagtt aaatttgctt
    31381 gctgtttgta ctaatagtgt agctggacga gcgtggatcc cagtttctgc tactacgtga
    31441 aattctttct tttccatatt aatcggtctc ctttaagtga gtgttgtttt tatgtgaggg
    31501 ttttcttttt tagtaattca gagaatccta acaaatgcca ccctttcatc tgtaaagatt
    31561 aacatttttt ttcgttagat acaacagttt tcattcaatt tcagataaaa gtattcaaat
    31621 tattccggat tctttttcat ccttttcttc acattttata acaaacgtgt ttatttcctt
    31681 tttcttgtcg ctttctcttc tcctgacgtt tatcattctt tcctttgacc ctctttgttt
    31741 tcatatgaaa cgaattactt gcttcccttt ttatttttag tataataaga gtcaaaggtc
    31801 aggaatggtc aatagagatt tcaccttttc tacctcataa atctcttaaa aaactagggg
    31861 ttattctttt acctcatgaa aaacgagatg taaaatatgg atgtacccat ttttgtgaaa
    31921 ggacgtgaat gattcatgct ttgtcaaaac tgcggcaaga atgaggcaac gattcacttg
    31981 tatgccactg tcaatggtca gcggacacaa ctcgattact gtcagagctg ttatcaaaaa
    32041 atcaaaaatc aacaaaatgg aggtctgact aatatggccc aaaatgatcc atttggattt
    32101 ggcagtttgg acgatctttt ccgttccatg tctcgccaaa tgcaacagca aggaaattat
    32161 gagcaaacac caccaacaca atttggcgga aacaacaact tcaatggtgg tcagccacct
    32221 caaggcaata cagaaggttt attgggagaa tacggaatca atatcacaga acaagcacga
    32281 caaggtgata tcgatcctgt gatcggacgc gatgacgaaa tcaaacgagt cattgaaatt
    32341 ttaaatcgcc gaaccaagaa caatcctgtc ttgattggag aaccaggtgt tggtaaaaca
    32401 gcagttgttg aaggtttagc acaaaaaatc gtagatggtg atgtaccgca aaaattaatg
    32461 gacaaagaag tcattcgttt agatgtcgta tctttagtcc aaggtactgg tatacgagga
    32521 caatttgaag aacgtatgca aaaattgatt gaagagatcc gtcaagcaga aaatgtgatc
    32581 ctattcatag atgaagttca cgaaatagtc ggtgctggtt ctgctggtga tggaaatatg
    32641 gatgctggta atattttaaa accagcttta gctcgaggag aattgcaaat ggttggtgct
    32701 actaccttaa atgagtaccg catcatcgaa aaagacgctg ctttagaacg tcgtatgcaa
    32761 cctgtacggg tagatgaacc aactgtcgaa gaaacgatca gtattttgaa aggtttgcaa
    32821 aaacgttatg aagactatca tcatgtaaaa tatactgatg aggccatcga agcagccgca
    32881 actttatcca atcgttacgt ccaagatcgc ttcttgccgg ataaagccat cgatttgcta
    32941 gatgaaacag gttctaagaa aaacttgacg atccaaatcg ttgatcctaa aacaatcgag
    33001 aaaaaactgc aagaagcaga agaacaaaaa gttttagctt ctcgagaaga agatttcgaa
    33061 aaagcagctt attatcgcga tcagatcaat aaacttcaaa aaatgaaaga acgtcagctc
    33121 actgaagagg aaacacctgt gattaccgaa aaagatatgg aaaaaatcgt tgaacaacgg
    33181 acaggtattc cagtgggtga attaaaagaa aaagaacaga cacaactgaa aaacttagca
    33241 gatgacttga aagctcatgt catcggacaa gataacgctg tagatcgagt agcgaaagcg
    33301 attcgccgaa accgtgttgg attaaacaaa cagaatcgtc caatcggctc cttcttattt
    33361 gttggaccaa ctggtgtagg taaaacagag cttgcgaaac aacttgccta cgaactattc
    33421 ggttcacaag attcaatgat tcgtttcgat atgtctgaat atatggaaaa acatagtgtc
    33481 tctaaattga ttggttctcc tccaggttat gtcggatacg aagaagctgg tcaattaaca
    33541 gaaaaagtac ggagaaatcc ttacagtctt gtcttgttag atgaagtaga aaaagctcat
    33601 ccagatgttt tgcatatgtt cttgcaaatc ttagatgatg gtcgattgac agatgcacaa
    33661 ggaagaacgg tcagctttaa agatacgatc atcattatga caagtaatgc cggaactggt
    33721 aaagtagaag caaacgttgg ttttggtgcg gcacgcgaag gtgttactcg ttctgtattg
    33781 aaccaattaa acaactactt tacaccagaa tttctgaacc gttttgacgg gatcatcgaa
    33841 ttcagtgcat tatcaaaaga aaacttgatg acaatcgtca cactaatgct agacgatgtc
    33901 aaccaaatgc tggcagcaca gcaacttcac atcgaagttc ctacgaatgt caaagaaaaa
    33961 ttagttgact taggctatga tccatctatg ggtgctcgtc ctcttcgacg cacgatccaa
    34021 gaacaaatcg aagatggtat cgctgaattt tatcttgatc acccttctat ccatgagttg
    34081 aaagcaaaac tggataaaga tggaaaaatc atcgttactt ctaaaccaga acgtttggct
    34141 aaagaatcag ccgaagaaac ggctgaataa atccagtttt atagcgtgag acggtatttc
    34201 tttgagaaat gccgtctcat tcttttttca gaaaagtcaa aatactgttc attttataaa
    34261 aaagaaatta taataagaga aacaagcaat taaaaataca taaaagaggt gagcgccatg
    34321 aaattggtaa atgtaacaaa cagccattcc cgtcttgtat taaaccagct tgaaaacact
    34381 gatgcccatc tagtcaaggt ctacacagcc ggaaatacca ctattgtcta cactgaagcc
    34441 cctcaacata atgaaattct gctgatcaat gacaaacgta aaatccagcc gaaagaaatc
    34501 gaagatgcta aaaattattt cttagataaa atcaaagacg ccgtttacca cgaggatgaa
    34561 atcaaagtaa tcgaattggc aggccttgtt gaaatctcga ttccaaaaca tgaattaggc
    34621 gctacattag ccgtgtaaac aaattttgaa cataataatt aaagagcgtg ggacaaaagt
    34681 aaag
//
LOCUS       DAZKNV010000028        34520 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000028 DAZKNV010000000
VERSION     DAZKNV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.028"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            212..604
                     /locus_tag="ACG8M1_001478"
     CDS             212..604
                     /locus_tag="ACG8M1_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0422199.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACG8M1_001479"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACG8M1_001479"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFQ0422200.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACG8M1_001480"
     CDS             2698..2943
                     /locus_tag="ACG8M1_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422201.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACG8M1_001481"
     CDS             3165..4775
                     /locus_tag="ACG8M1_001481"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFQ0422202.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACG8M1_001482"
     CDS             complement(4752..4964)
                     /locus_tag="ACG8M1_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422203.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACG8M1_001483"
     CDS             5067..5936
                     /locus_tag="ACG8M1_001483"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFQ0422204.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACG8M1_001484"
     CDS             6101..7372
                     /locus_tag="ACG8M1_001484"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFQ0422205.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACG8M1_001485"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACG8M1_001485"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFQ0422206.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACG8M1_001486"
     CDS             8763..9026
                     /locus_tag="ACG8M1_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFQ0422207.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACG8M1_001487"
     CDS             9471..9920
                     /locus_tag="ACG8M1_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0422208.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACG8M1_001488"
     CDS             9977..11395
                     /locus_tag="ACG8M1_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFQ0422209.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACG8M1_001489"
     CDS             11395..12255
                     /locus_tag="ACG8M1_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFQ0422210.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACG8M1_001490"
     CDS             12429..13202
                     /locus_tag="ACG8M1_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0422211.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACG8M1_001491"
     CDS             13349..13714
                     /locus_tag="ACG8M1_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFQ0422212.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACG8M1_001492"
     CDS             complement(13862..15070)
                     /locus_tag="ACG8M1_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0422213.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACG8M1_001493"
     CDS             complement(15089..15367)
                     /locus_tag="ACG8M1_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422214.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACG8M1_001494"
     CDS             15560..16216
                     /locus_tag="ACG8M1_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0422215.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACG8M1_001495"
     CDS             complement(16658..17455)
                     /locus_tag="ACG8M1_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFQ0422216.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACG8M1_001496"
     CDS             complement(17452..18636)
                     /locus_tag="ACG8M1_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFQ0422217.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACG8M1_001497"
     CDS             complement(18661..19908)
                     /locus_tag="ACG8M1_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFQ0422218.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG8M1_001498"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG8M1_001498"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFQ0422219.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACG8M1_001499"
     CDS             21888..22202
                     /locus_tag="ACG8M1_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFQ0422220.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACG8M1_001500"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACG8M1_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFQ0422221.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACG8M1_001501"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACG8M1_001501"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFQ0422222.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACG8M1_001502"
     CDS             23546..23875
                     /locus_tag="ACG8M1_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFQ0422223.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACG8M1_001503"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACG8M1_001503"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFQ0422224.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACG8M1_001504"
     CDS             24863..25687
                     /locus_tag="ACG8M1_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFQ0422225.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACG8M1_001505"
     CDS             25680..26027
                     /locus_tag="ACG8M1_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFQ0422226.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG8M1_001506"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG8M1_001506"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFQ0422227.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ACG8M1_001507"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ACG8M1_001507"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFQ0422228.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG8M1_001508"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG8M1_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFQ0422229.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG8M1_001509"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG8M1_001509"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFQ0422230.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACG8M1_001510"
     CDS             31684..32451
                     /locus_tag="ACG8M1_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422231.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACG8M1_001511"
     CDS             32441..34483
                     /locus_tag="ACG8M1_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422232.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLITGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
BASE COUNT        11101 a         6122 c         7247 g        10050 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttattta caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt ttgtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa cgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat
//
LOCUS       DAZKNV010000029        32048 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000029 DAZKNV010000000
VERSION     DAZKNV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.029"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..245
                     /locus_tag="ACG8M1_001512"
     CDS             6..245
                     /locus_tag="ACG8M1_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422233.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            312..521
                     /locus_tag="ACG8M1_001513"
     CDS             312..521
                     /locus_tag="ACG8M1_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422234.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            581..1252
                     /locus_tag="ACG8M1_001514"
     CDS             581..1252
                     /locus_tag="ACG8M1_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFQ0422235.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1305..3281
                     /locus_tag="ACG8M1_001515"
     CDS             1305..3281
                     /locus_tag="ACG8M1_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0422236.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            3294..4049
                     /locus_tag="ACG8M1_001516"
     CDS             3294..4049
                     /locus_tag="ACG8M1_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0422237.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            4046..4870
                     /locus_tag="ACG8M1_001517"
     CDS             4046..4870
                     /locus_tag="ACG8M1_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFQ0422238.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            4880..5128
                     /locus_tag="ACG8M1_001518"
     CDS             4880..5128
                     /locus_tag="ACG8M1_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422239.1"
                     /translation="MKIIRILVFNLSFLAATILCCGLIFSQLSIYPRYQRLFIHFLNI
                     QCASMPLEVIKKLLINPIFMVSLVLLTGLVTWVLGKKE"
     gene            5171..7270
                     /locus_tag="ACG8M1_001519"
     CDS             5171..7270
                     /locus_tag="ACG8M1_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFQ0422240.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(7308..9365)
                     /locus_tag="ACG8M1_001520"
     CDS             complement(7308..9365)
                     /locus_tag="ACG8M1_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFQ0422241.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(9479..9691)
                     /locus_tag="ACG8M1_001521"
     CDS             complement(9479..9691)
                     /locus_tag="ACG8M1_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422242.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            9878..10345
                     /locus_tag="ACG8M1_001522"
     CDS             9878..10345
                     /locus_tag="ACG8M1_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422243.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            10342..10584
                     /locus_tag="ACG8M1_001523"
     CDS             10342..10584
                     /locus_tag="ACG8M1_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFQ0422244.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            10602..10904
                     /locus_tag="ACG8M1_001524"
     CDS             10602..10904
                     /locus_tag="ACG8M1_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422245.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            10976..13030
                     /locus_tag="ACG8M1_001525"
     CDS             10976..13030
                     /locus_tag="ACG8M1_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422246.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            13030..15642
                     /locus_tag="ACG8M1_001526"
     CDS             13030..15642
                     /locus_tag="ACG8M1_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFQ0422247.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            15639..18170
                     /locus_tag="ACG8M1_001527"
     CDS             15639..18170
                     /locus_tag="ACG8M1_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFQ0422248.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PEQAKGMAGNDKSGLSDIQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            18222..18554
                     /locus_tag="ACG8M1_001528"
     CDS             18222..18554
                     /locus_tag="ACG8M1_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422249.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            18555..19148
                     /locus_tag="ACG8M1_001529"
     CDS             18555..19148
                     /locus_tag="ACG8M1_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422250.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19311..21005
                     /locus_tag="ACG8M1_001530"
     CDS             19311..21005
                     /locus_tag="ACG8M1_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFQ0422251.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEIVKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            21693..23570
                     /gene="ltrA"
                     /locus_tag="ACG8M1_001531"
     CDS             21693..23570
                     /gene="ltrA"
                     /locus_tag="ACG8M1_001531"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFQ0422252.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            23701..24078
                     /locus_tag="ACG8M1_001532"
                     /pseudo
     CDS             23701..24078
                     /locus_tag="ACG8M1_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            24078..25283
                     /locus_tag="ACG8M1_001533"
     CDS             24078..25283
                     /locus_tag="ACG8M1_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0422253.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMS
                     IINTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            25299..25943
                     /locus_tag="ACG8M1_001534"
     CDS             25299..25943
                     /locus_tag="ACG8M1_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422254.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            25954..26760
                     /locus_tag="ACG8M1_001535"
     CDS             25954..26760
                     /locus_tag="ACG8M1_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422255.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            26782..27011
                     /locus_tag="ACG8M1_001536"
                     /pseudo
     CDS             26782..27011
                     /locus_tag="ACG8M1_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27557..27832
                     /locus_tag="ACG8M1_001537"
     CDS             27557..27832
                     /locus_tag="ACG8M1_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422256.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            27874..28296
                     /locus_tag="ACG8M1_001538"
     CDS             27874..28296
                     /locus_tag="ACG8M1_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422257.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            28315..29907
                     /gene="mobP2"
                     /locus_tag="ACG8M1_001539"
     CDS             28315..29907
                     /gene="mobP2"
                     /locus_tag="ACG8M1_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFQ0422258.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            29919..30254
                     /locus_tag="ACG8M1_001540"
     CDS             29919..30254
                     /locus_tag="ACG8M1_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422259.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            30401..30595
                     /locus_tag="ACG8M1_001541"
     CDS             30401..30595
                     /locus_tag="ACG8M1_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422260.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            30627..>32048
                     /locus_tag="ACG8M1_001542"
     CDS             30627..>32048
                     /locus_tag="ACG8M1_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFQ0422261.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKK"
BASE COUNT        11834 a         4966 c         6548 g         8700 t
ORIGIN      
        1 agtagatggc gcgaccagtt ttagaggcga tggatatgga tactttgaca aaaggaaggt
       61 atgtacagct gttagctcgt ggttattcac ctaaagaagt attcaaagcc ttatctaaag
      121 gaacagatat ggaaaaagaa agattgcgaa aagaattcga ttattggaga acccataatg
      181 gaatcaagga tttgaaacca gcacggccag taattaaacg aaagaaaaag ataacccaag
      241 actgaagtgt agagcgtatg tgatcatagg cttttttatt tttgcaaaaa acaaggaagg
      301 taggaaaact catgaattat gaagaaatcg aaaacagaaa aaaagtgtcg aaagaaatgg
      361 aagaaaagtt actaaaaacg atgaagcaaa aacaccttaa aagattatct gtcgcgcaat
      421 atatcaatga tatgcagtta acaggaaaag agaaagcttg tttgttaggt tcaatgaaaa
      481 actttgaaca gttgagacga acttatagaa ttcattttta aaactttttc tatggaaatg
      541 agaaaaagtt tttttgtttt gtctgaaagg aggcagatgg atgaaaaaat ggttatttgg
      601 ttttttagga gtcactttaa tcgtcttttg cagtgtgttt ggctatgtta gctaccaaaa
      661 acatgaagga gaggtgttta agcaaaatat agaaaaaaag atgcccgtag atcaaatcaa
      721 tgcacatgca aagagttata aggaggatgc aacgaacgtc aataatgata tgtctttggg
      781 gcaaatgttg tccatacaaa aagaagcaat cgaaatgggc gtcaataaac aagtatttgc
      841 acaaattcag attcctgcac ttggtttagc attgccaatt tttaaagggg caaatcaata
      901 cactttgagt cttggagcgg ctacttattt ttatgaagat gccgaaatgg gcaaaggaaa
      961 ctatgtccta gcaggtcata acatggaaat gccaggtgtt ttattttctg atattcaaaa
     1021 gttgtcatta ggggaggtga tggacttagt tagtaacgat ggcgtctatc gttacaaggt
     1081 aacgcgtaaa tttatcgtac ctgggtactt taaattaatc gatggcgttc ctgaagagaa
     1141 ctctttcttg tctttgccaa agaaaggaga gaaaccctta ttaacgttgt ttacttgtgt
     1201 ttatacgtca caaggaaaag aaagatacgt ggtacaggga gagctacaat aacaaggttt
     1261 taatcaacgc gagtcgttga aatatgaaat gaggagagta aaaaatggca ataaatcggt
     1321 atgtaaaaaa agctggaatg cttgttggaa tgttaggaat cattgcaggc tgctttcagg
     1381 ggtatcaagt acatgcagaa gatgtcacgc aaaaaacacc accagagaag gtcaatatca
     1441 cggttcataa attaatgtac gatcaaggaa cgcaattgaa tgttgatatt gacgggatca
     1501 aaaacgatgg ttatacgcac gatcaatatc ctacaggtgt aacgaaatac aacaaggcag
     1561 attatggtga tgttgagttt acgttaggaa atattacgga tcaagtatta ccgagagaag
     1621 attctgatct aaccaacgcg aaagtggacg agattgtaca agatgtagaa gacaagggat
     1681 ctaacagtga gtacgtcaag aatgcaacca acaaaattac ttcagctgta gatgaaaatg
     1741 gtgagatcac ttttactgat caaccagcct atgtcaattc caaagggaat gtatatgtgg
     1801 tttatgaaag taaatccgct gctggattag tcacacaaaa agcaaaacca atggttgtga
     1861 ttgcgccaat gacagataaa acaggatcag gatttttaaa aaatattcat ttgtatccta
     1921 agaacattgt ttctaagttg agttttgaat taacgaaatt tggtgacgat ggcgcagacc
     1981 aaagcaaaca aaccctttta aaaggggcaa aatttgagtt atacaagggc gaacctggaa
     2041 aaggaacaaa attgggtgat cttgtatcgg atgatcaagg aaagctgact gcgactgatt
     2101 tgacgttagg aaaatactat tttgtggaag ttccttcgga agttgtagtg ggatcagatc
     2161 aagaaccaac agcagatcaa tatttattag gcgcagacgc tcgcaacgat gcgcacaata
     2221 aattaacctt tgaaattacg aatgatggcg tgacaagtga cttaaaagct tcatacgtaa
     2281 actataaagc accagtgatc gataaaacag taacaaatgg aacaggacaa gaacattctt
     2341 tccaaattgg tgacgcagta aattatcaag gaacgattca tattccaaca gacattgcag
     2401 gtggcgcaga cggtatcaca gtaaacggtg tgaaaagcga aacttctcct tacagtgtat
     2461 ttaaatgggg agatacagca ggtaaaggac tttcttatgt tgctgaaaaa gcagatatta
     2521 aagtaacaaa taatgatggt tcagtcgtat taaaagaaaa tactgactat aaaatcgaaa
     2581 attctgatag tggttttgtg atcgatttta tcgtaaataa tggacaagta agtgatacag
     2641 ttgcgaattt acatggtcaa gatctaaaaa tgacttataa catgtttgtg aatgatagtg
     2701 ctgaaatcgc aaatccatta acaaatagcg tggatttcgt ttataacaat aatccattta
     2761 atcaggaaga acaccacgaa aaaacgaaag ctgacgttgt gacttatggc gcaaaattct
     2821 taaaagtcga tagcggccta tttggaacag gtatcaaagc aacaccgctt gaaggcgcag
     2881 aatttgcagc taagaatgca gaaggtaagt actacggtgg acttactgat acagataaag
     2941 atggtgtcaa agaagcagtt tgggtagacg atgtagcaaa tgcagcaatc ctaaaatcag
     3001 ataaagaggg tcattttgaa atcactggtt taactgaagg agattactca ctggaagaaa
     3061 caaaagctcc tgaaaactat caaaaattaa caaaagagat ctctttcaaa gtagacaaag
     3121 attcatacaa agaagaaaac cgaatcacga tcaaaaataa tcaaaaagct tccgtaccaa
     3181 tgactggtag caacggtttc caatcttacg tattgatctc ttgcttgttg ctaggagcag
     3241 ggggactttc tgcagttgtt tactttaaga agaaagccta gaaggatcag ctaatgatta
     3301 ttcgtaagcc cccaaaaaga agagtcatgc acaaactgat gatatttttt tggttgctgt
     3361 cggcagtagc agtctattta attccagttg tggaaacaaa tgtagcgaaa tttcaacaac
     3421 agcaaagaat tttagccatt gaaaatcttg aaaaaacaga ttcttctttg gatgttgcga
     3481 aaatagagtt aggcgatcct gttggtgttc ttacaattcc aagtatttct ttaaaactac
     3541 caatttatga cggaacttcc gacaaaattt tagagaatgg tgtagggatt acggaaggaa
     3601 ctggcgatat tacaggagga aacggtaaaa atcctttaat cgcggggcac agtggacttt
     3661 ataaagataa tcttttcgat gatttgcctt cagtaaaaaa agggcaaaaa ttctttatta
     3721 aggtaaatga agaacaacat gcctatcaaa tttatcgaat tgaagaagtt aaagcagaag
     3781 aattacaaaa aaattattta gattatctta tgcctgaaaa agaccaagat aggatcacgt
     3841 taatgacatg cacaccaaaa ggtgtcaact cacaccgctt tttagtgtat ggtgaacgag
     3901 tttccttcag taaagaagat ttaaaactac agaaaaaagc aaaaaatagg aaatcaattt
     3961 cattggattg gcgattagca ctgctattcg cttttttttg cgttcctatt atttttattt
     4021 ataaaaaaat aaggaggaga tcggaatgaa taagagaaaa tggctgtttg tttgtgtagc
     4081 agctctcttt tctactgtag cttattcgca actgtctttc gctgacagca gtgatagtag
     4141 taccactcaa acaatagata attcaattac tgcaccaagc gaaacggaca gttcggagaa
     4201 tactacagaa gaaacggcag attcaaatat aagctttact gaatcaacga atccaacgtc
     4261 agaaagttct tcagagactt cagaaaagcc gcaagacgta gaagatacgc aagtgatcaa
     4321 gcaagccatt catattcaaa aaattatttc ttcgaatcaa atcaacaatc aaggcagtca
     4381 agtagcccag caagaaggta tcaatggcgc gaagtttatt gtctacgata tcacgaatat
     4441 cttagaagaa atgtcacaag atgataatga gaaaaatcaa tctgtagaaa taattgagtc
     4501 aaaattgaaa gatcgagcaa aaaaactttc atacgaccag ttgaaaaaag tggctgaagg
     4561 agaaaccaaa acgattgatg atcaggaagg cgtgattgaa ttttccattg aagtacctgc
     4621 aaacaaaaaa caagcatact atatcgttaa tgaatcaagc cctgaaaaca tttcaaacag
     4681 tgaagatatt gttttattga cacctgtttc aaatgaaaaa ggtgaatttt tgacggatgt
     4741 ttggttatac cctaaatcag agaaatcaga gccgaaagaa gaaattaaaa aagttgtgtc
     4801 aactggtgta aagaagaact tttttgaaaa ttgttgggaa ttttttgctc aattattttt
     4861 tgataattag gatgaaatga tgaaaataat aagaatatta gtttttaatc tatccttttt
     4921 agccgcaaca atattgtgtt gcggtttaat tttttctcaa ttatcaattt atccaagata
     4981 tcaacgattg ttcattcatt ttctaaacat tcaatgtgct tccatgccat tagaggtgat
     5041 taaaaagctc ttgatcaatc caatttttat ggttagtttg gttcttctta caggattggt
     5101 aacgtgggta ttaggaaaaa aagaatgaaa agcttacgat cgtttaaaaa aatattagat
     5161 ggagggcatt atggaaaata aaattcattg cactacggga agagtaatta ctttagtgtt
     5221 gtttttgttc cttcttcttt ttgcgagggg aactgcagtc caggccttag aaaaagttga
     5281 tccgagtcaa atcaaagaaa ataataatct ggtgctttat catgatagtg attcattgag
     5341 aaatatcgaa gtaactggga tcaatggatt taagatacta gatgagtatt caactaaaaa
     5401 acaaaaagta cttgcttggc caaaagtcaa agatttgaaa agtacgtcaa aaatcgttgc
     5461 ccattatcaa aaagtaggta cttatctagg aaaagaaatt gattgtgacg tgactttttc
     5521 taattttgta gcgcacgctg gggttaacca agacggatta gctaaaacaa ttaatggcaa
     5581 aaagtattat aattatttgc tctttgataa aaatatttat cgaggatttt tcatgcagtc
     5641 aatcaatgtc atgaatgcaa aactagaatt taagtatgca ggaacaaaaa caaaagtagc
     5701 tttgagtgaa ccacagccag aaattcaatc aaaaatgaga tcgatgagag cagctggtat
     5761 tgatttaaac gatacatttc tatccattta cagtttaaat ggacagtatc agcaacgtgt
     5821 gtcttggtat aatgacaata atgaatctgt cggtgaacgt aatattgata tgagagaatt
     5881 tgttgggtat gaaaaaatgg gtagcttacc ttattttgtc acaacagata cagcatgtgc
     5941 agaatacaaa gctcctgcgt tatcaacaaa caatttaact tcaaaagtag tgggaggacg
     6001 tgcagaaaag gcttatagct cgaatgatca tttcaccgat gttgtaggag ctgatactta
     6061 tcacagaagt ggtgtaacgt atacgcttca aggcgcttcc ccaacattca tgattggcgc
     6121 aaatacgaat agtatgatgt ttagctttga tactgcattg ctatggacac cacaaccatc
     6181 gaagcctaca aaagaagtgt ttaacaaagc taatactgaa gaggcagcac acaatattga
     6241 caaaaaagtg attccacaag gatcagatgt ttactatcat attcaccaaa agtttgatgc
     6301 attaacagtc aacacaatga acaaatacaa atcatttaaa atcactgata cctttgacag
     6361 caaaaatttt gatatggtat cggatgggaa aaactatgat ggcgcattgt ggtatgttga
     6421 agcgaatggt acttggaaaa aagctgatac aggaggaaag ttaactgtat caggtaatac
     6481 agtcacttat actgcttctg acagcttttt agctaacgct gcaaattacg gtagggatta
     6541 tattttgcag ctccatatga gagcaaaaaa tgatgcaaaa ggaattgcac caaatgtggc
     6601 tactgtaacg tttaacaatg atccgaacaa aggaacacaa aaaacaaata cagtagaaaa
     6661 ctatttctct cttaaaccaa ataaaaaagt ggaacaagat gggaaagatg ttgatggtcg
     6721 aaatgatggt aaaaaaggaa cgcctacagc tcctttaaat gcaggatctg aagtacaata
     6781 tctagtcaca caaaaatggc atacaaaagg tgtagacatt gcctcagatc attacaagca
     6841 atttagtatt caagatccag tggaagatcg tttgacgtat aaagaaggtt ctgcgcgagt
     6901 gatagatatg agtacaggaa aagatattac ttcagaaggt acactaacct atgatagcaa
     6961 ttcaagaacg ctgaagtggg aagcttccgc tgatttctta agtaaaaatc ttttagatgg
     7021 acgagaaatt cagctgatat ttacagctaa aactcctttg aatgaagaat tggatatcga
     7081 caaccaagca aaagtttcag tagaaagtat tgagaaagca actaatgtag taacgattgg
     7141 ggtaaaacct aacttacctc agatcattgt gccaaaaact ggatcgaatc atttagtgct
     7201 aactgttatt ggaagtatat tatttcttac tttagcatca ttgggctatg tagttttaaa
     7261 actcaaataa atataaaaac aaggctgaga atcagccttg ttttctttta tttgaagatt
     7321 ggattcgcac taataaatac attatctacg ccaattctac cagcagagtc aactacaaaa
     7381 ttatgaccta atccgagaat actttggtta ttataaagta aatttgcatt atgggcaggg
     7441 ctatttttcc atcctaccat ggcatcgata gcaccatcgt ctgataaaag gtcatcaata
     7501 tacagcccag tttgacttat gttttctccc ttagcaccgt agcagcctaa gctttccaat
     7561 aaatcttgga aagtaccacc accagggcga tagtgactga agctgacttg taattcttta
     7621 gctcgaatat ctgcagcctg ttgaacaata tcattgaatt gcattggggc aacaccattt
     7681 tgttggcgat aatcatttaa ccaagcaagt tctttttgac gcataaagtt acgtaattcg
     7741 tctaatgaaa tctttttata tttgaatgtg attgttttat tttgatcgac gttattaatg
     7801 gatcgttggc cgtttttatc cacggtaacg gtaggatcgt catttctgca caagaaataa
     7861 ttttgatcag tcatgttttt ccaaggagta gcaaagctat ccccttcgta tactgttttt
     7921 gattcactag agagaacagc gttggtatca gcatttacat gattaacagt cacattaaat
     7981 ttacgagtgt agttgaaaat ataattttga ctttcagtca cattgtttaa ggttactgaa
     8041 tttgttggtt ctacccgatc gtctaaaaca tatccttgaa tagaaggagc agttaaagtg
     8101 acactgtcac cgtgagtgac attgactatc tgttctttca aaatattaac tcgtccttcg
     8161 tttttgtagt tgttattgca caacaaattg atttgatgca cttgattata attgaatgtg
     8221 attgttgtat tacctgtgat tgttttgctt tgagtatcat taccaatcac tttgtagcta
     8281 aaattatctt tagcgccttc gctatattta aatgcttttg ccttagcagt gtaagtagaa
     8341 ccagaagtta cttttgcttg atctgtagca atcacttgac ctgtttgatt gtcaatatgg
     8401 ttaatagtaa ccgtatattc ttttggtgtt tcaggtttgt gttgcaaccc tttaaatgca
     8461 gcatcaagac tatttttagc attgtttact tgtgtttgag aaaccttaga atcgtctagt
     8521 acttttttag cattggataa agcagtctga aaattattcc aagattcttc tgtaaaatct
     8581 cctttagcag ttgattttac tcggttgtat aaagcttgta attcagcttt attcacagta
     8641 ggaactggtt ttttctttaa tcctttgtaa gcagaatcta atttattttt ggcactatcc
     8701 acttgctttt gagtcgcttt tgagtcattt aacactttct tagcattgtt taaagcggtt
     8761 tggaatgcgt tccaggtatt gtcggtatag tcaccttttt tcgttccctt aacgctcgta
     8821 taaagagctt ctagagccga tttattcact ttgggtttag aggtgtcagc gccataccaa
     8881 ccgatacctt cgtatttcca gccatagtct ttggttaacc attgtacttc tttccaactt
     8941 gcagtgtagt gatgtgagcc agattttaca ccaggaagga aaaggcggta gatcggttta
     9001 ttattttttt cggcagaacg ccaggcaggc ccttcataag tccagccgta atttttagtc
     9061 aaccatttca cttcatccca actagctgtg taatggtgat cacgaagacc tttattgtac
     9121 aaacgataga caagatggcc accgctagtc ggtgcttccc aggcggggcc ttcataattt
     9181 ccccatttta tctttactag atggtcacgt tcttttttgc tagaggtgta aaaatgttca
     9241 ttattatttg gattgtaaag gcgatacatg acgttagttg aagcagcgtc aacagatcca
     9301 gcaagactaa gtgaggcagc aaatgttcca atagctaaaa cagtttttgg attaaataat
     9361 ttcatttttt caactcctaa atttaattaa aaatgtttac atgattatta tatatcggct
     9421 aaccgatata gtcaataaaa aataagaaaa gccttatata attttggctt ttcttatttt
     9481 atttgttagt tgaagtatta atatcaacga tttcttcagc caatttattt aatttcatag
     9541 catttatgaa tctcatgttg tctatactag agcgtttgtt ggcaaggtca cttactgtag
     9601 ttaagggtac gccagattct atggatatag aacgaactga tttaccacta tcaaacagca
     9661 accattcgat tttcttttta tcagcgtaca tttcaatgct ccttcttgtt ttttctttat
     9721 tatagctctt ttttgtaatg aatcacaata tcaagagaaa aattttctat agaaaggtgg
     9781 atttttatga gtattcgttc tccgtgtatc caaatgaggt ttgttgctac tttcgttatt
     9841 tgatatacta aaaataaaca acgaaagaag gaataaaatg aagaaaaagc aactatggtt
     9901 tgtctctatg tttgcaatat tttttattat tttaagtgga tgttcaagta ataagaaatc
     9961 ggaagctaaa gaagataata gtttattgca accaggaact gtttggaaag aagaagtagg
    10021 tggtcttatt cataatttaa aaattataga tgatactacc tgggaatatt ctgaaagtgt
    10081 atggcatcca gatcctgtac aaataacagt taagaggcaa aaagactatg aaggtttaga
    10141 aagatacaaa atagtagatt ctgcaggcat tagggaattt ataaacaaac ctgattcatt
    10201 atttattgtt gttccctatg agaaggatgg cgtaaaaaaa ataatttttc ttggatctag
    10261 caaggatgag aagcgaacga aagagaaatt aattcatgat ggatcagagt taaataaata
    10321 caaattacaa aagactagtg agtgattgct agtcttttta tttatcctga aggaggaatc
    10381 acagtggcaa aagttaaaac accattcgaa aaagccgcgt ctaaaatctt agaacgccgt
    10441 ggtgtttctg aaatacagtg gaaaaaagaa gttcttgaaa aagcacaatt tgacctatta
    10501 cgaggaaaag ataaggactt agaagaatat atctatcaac gtgaacgtga aaaacttgta
    10561 ttcgatgaaa ttattaaaca ttaaaaggag cgaataatct tatgtttgaa tcaattacaa
    10621 tgaatttttt aactcaaccg aaagtagtag ctgcagttga tatttttaga gcattacaaa
    10681 ctgccgcaac tagtttgaaa aataatctga tgatttttgc tgctgttgcg gcagtggctt
    10741 ccattgctct tggaggtatt ttcttcttct ttgggcgaag aggagctgaa aacgggaaga
    10801 cacacgtagg ttatgtattg ttgggggtag gagttatttt agctgccgct tctattgtag
    10861 tttcaatgtt ctcaatgttt ggacaaaccc cacaaggact ataaaaaaaa caagtaggag
    10921 gagtaaaaag tacgtggcta ctttttactc ctttttttat gaaaggagaa tattcatgtt
    10981 ttttacgatt tcaggaaatg caaaattgga taaagagtta ataagaaaag caacgaagaa
    11041 agtgggaaag cgtacttcct ttttaccgaa aacaattaaa tattctgtca ttgaaacgga
    11101 agaacagcta catgtgttag gacaagtgtt agaacaagag aatcaatctt ctgttaaatt
    11161 gactctcacg ttacatgata aagaaggaaa aatagaaaag gctggcacag aatacgtttt
    11221 tggcccactg gattatcaaa tttcagaagg tttttatcct acattgatag atttaatccg
    11281 ccttgatgtg tttaaagata cggatgaaac tatgagtgtg gaagagtctt atcgaaacga
    11341 aaaactttta caagttttag aagaagagtt agagagcgac caaagaaaag tgaatcaagt
    11401 gagtgaagtc gaagtaaatg aagaagtacc atgggaacga ccaatctttc caaagaagga
    11461 gtcaaaagaa aaagagacag tctatgttga cgaacaagct gatattccga ctcagaaatc
    11521 gatatttgag gaagagaacg atgtgatggg tcaattggag gtagatccct ttgaagaaac
    11581 aatggaggat gaagagacgg acgaagtaga agttgatcca gttgaagcta atgaagagtc
    11641 aacatggact gaaggggatt ttcaggaata tattgaacca cttatcagtg aagaagtaga
    11701 aaaaaacgaa acagagatac aaaaggcaac tgtatttgat tatattttgg atcaatatcc
    11761 gccagagcat gaatggatga aagaaaaaaa caaattattt ttaaatgagc tttattcgaa
    11821 atatcaatta ccccaaacct atcaagcatt tttagagagt aaagaagaat taatctcaca
    11881 gggtaaaggc acacttttag aacagttaga gtctgtccaa tcaacaaatt ggcatgagct
    11941 tgcacaagaa gatttattag ccacctttga agaacgtcaa caagaaacag atcaagaaat
    12001 taatgagtat gcgacggaac agtcgtctaa ttgggagaaa gtaaaagagg aactaaataa
    12061 agaagaacag cgagtgattg aagaagaagt acaaaaagtc aaagagcggt acgaaaagaa
    12121 acgcgacaat gcttattcct tgtgtgtaga aaagatcaac aattttacta agacgaatca
    12181 agaagcgtta tcgaaagaaa aagaaaactt gttaaaagaa cgtattaaag aacgaaaaga
    12241 agagttctac cgcggtttac gtacagataa gctaaagatt agcaaagaat taaatgaaca
    12301 actgaataag ctatatcaaa caacgactga agttcttatg gaaaaacacg aacagatcca
    12361 gcaagaatta caagtacaaa ttccaaaatg gaaaaaagag tatgaaattc aacaacaaga
    12421 attgaaagaa caagaagaaa aacaacggca aaaagaaaaa gagcgtgaac aattagaaat
    12481 aagaaaacgg gaacaggatc ttgcggaaca aaaaatggcg atagaaaaac aacggttaga
    12541 gcaagaaaag gaaaaagaag cagctgctcg taaggaacgt caagaacaaa tggatacatt
    12601 gcgtcaagca cagttgaatt atctagcaca acctcaacca gtagctgctg ttcaaacgcc
    12661 agtgaacaac caagcaaatt taactccttc accccagcgt tcctttaacg gatggatggt
    12721 gggatgtatt gcaagtttaa gcttgcttct aggtggagga acagtatttg cttttaatca
    12781 tatcaatcaa tcttcacagg ctgattctgt agccacaacg gcgtcaatca aggaagaagc
    12841 ccaggaacaa gcaagaaaag agtatgaaca acaattagaa gaattattga atcgtaccaa
    12901 tcagtcaaca acagagtcaa gcatggaaaa tagcaaagag agtgattcta gtaaggctaa
    12961 agaaggatca agcgattcaa ctgtacaatc aaacacttcc gaaagttcag aatcaaatga
    13021 ggtgaaataa tgcgtgttag agaaacaacg aagcgaaaag acaaacgatt caatttagaa
    13081 aagaataggt atctttctca tttctatcgc tatactccct caggagaaga gctaccagaa
    13141 aaacatgaca aacgcatttc gaaaaagatt ttttatagtg gacttgtata cctcccttta
    13201 gagtatttag taacaagagt accagaagtt ttcaaccgat tggaaattgt taagggaagc
    13261 ttacaaggaa taaatctgtt tcaattacag gaaatgccac aggtctttca ttttgattca
    13321 gctggttttt ggaatccatt tactcctaca actagtttgg gtacacgttt agcaatttcg
    13381 acagtttgtg tggttccagc tgtacttatg ggattgaaaa tggacatgtg gtttcgtcct
    13441 ctagcagatg gacaaaaagg ggataatcga ttaatgacct taaaagaaat ccaacagatt
    13501 tatccgcaaa tacctgaaac aaaaactact tttccaggtt atggaggtat tccaatcaca
    13561 cattacaaaa aatattggta cattcaaaca gatactgtta atacgtgtat tgttggtacc
    13621 tctcgatcag ggaaaggtca gattgaagtg ttagccacca ttgacaattt atctcgtgca
    13681 gaaaaacaaa gttcaatggt cgttaatgat ccaaaaacag aattatatgt tggtagtaaa
    13741 gatgaactag aagctagagg gtatgatgta tatgccttta atatcaccga tccactgcaa
    13801 tcaatgagtg ataatccatt ggcactcatc gtgaaatact ggaaacgagg agacatagat
    13861 actgcaacac agttaaccaa tactttcaca aatacgattt attatgatgc caacgcttca
    13921 gataacaaat actttaacga aaacgcgcag aaagctgtca atgcgcttat ttttgcgttg
    13981 ttagaacaag ctgatcaaac aggagattac tccaaattga caccgaataa tctcgttgag
    14041 cttctttctg agattggcgg ttttaattat tatccagatc cagacaatga attcaaacag
    14101 ttgaatgcct tagatgaatt tatgaatcag ttgccacctg gaaacattgc aaaaaaacaa
    14161 tatggggcaa cgaaaattgg atctgataaa gcgaagggaa atattttatc aacggcaatc
    14221 acgggattga atccatttac tctaacgaaa attgcaaaga tgacttctca atcaacgatt
    14281 gattataaat cggttgggtt tccaaaatac ttagatttga aattacatga aagtctttta
    14341 aatcaacgag tcgtagtaga attttatcat aagggaaaga aatttcatga agaacgtgtc
    14401 aaagtaggct ataaaggatt tagtgaaatc aattttgatt gtcatttagt tgcaggtgat
    14461 caagtttgtt taaaatacga tcatcaagga aaagaatatg tggcttggta tgaattttct
    14521 caaagagtat tgaaagacga agagggtaat atcgtttatc ggaaaaaacg aggagaaacc
    14581 catttgccag aattagaaaa agaagccgtt ctaacattag atgaggaaaa aagtaactta
    14641 ttagtagagt ctattcggat gcactatacc gataaaccaa tggctatttt tatgcttaca
    14701 cctgattatg atccatctaa ccatatcatt gttagtattt ttcttagtca gttatataaa
    14761 gaattatcta cgcaatgtgt taagactaaa ggagataaat gtcaccgcag gattcatttt
    14821 attttagatg aatttgggaa tatgccacca atggataata tggaaggaat catgacggtc
    14881 acagctggcc gaaacatgtt gtgggatctg tttattcaat cttatcagca actttatgcg
    14941 aagtatggag aacaaaacgc agcgattatc aaagaaaatt gtcagacaca tatttatatt
    15001 atgtcgacag atgataatac catcgaagaa ttttctaaaa aagtggggaa taagacggtt
    15061 gaacaagaga acagtaccat caattcatta ggtatgaata ctcatatcaa tcgcaatgtt
    15121 gattcagatc gtatcttaac tcctgaaaga atttctactt ttttagaagg agaaacgatt
    15181 gtactcgctc ctttaaaacg acaagatttg aaaggtcata aaatacggcc gtatcctatt
    15241 tttaatcatg gggaaacgaa tcttccttat gcttatcaat atattgaaga tttcaatcca
    15301 tcgtgggata tcaatgatat agacatacat tgtacacatg cggacttgga tcttaaggct
    15361 ttacaaattg attatgatta tttcctacca gatgaatatg ctagaaatct ctatcatgga
    15421 ctgcatgatc aattagaaga aaaaaacgaa gaaaatatgt tttataaaat cgttcaatct
    15481 cttgagaatg agacggctaa aaaattgtta attcaatttt acgaagaaca agcagcagat
    15541 cgacttcaag aatatgttga aaagttgatc aaaaataaag aaatttctga aatgattggg
    15601 aaacggttgt tattggaatc tgaaaaggtg gtgaaagaat gatcattgga ggaatttttt
    15661 ctggcatagc cgactggtgg tcaggcttat tcggagaagg ggatgcaaac cccaaaaccg
    15721 taacgaaagt cttacaagat tatgggaatt atctgcagta tcaagatgta tttagttgga
    15781 tttggaacac ttttctgtgg ggattgatta aaggattata taatctcaat actttactag
    15841 aaaaaaccat ttatcaaagc tttgatttaa aagacttatt gaacgccgct ggggtaaatg
    15901 cactatttca aagtttgatt agtaaggtat tggctctttt ttgtgtcgtc acattaattt
    15961 atttaggctt gaaatttttt atgagtaaac acccaccaaa agtcaaaaat atcttggtta
    16021 atttatttat ggccatgatc ttgatttttg gtggtagttc tttaatcgat gaagggttaa
    16081 atatcagtaa aagcttttac ggagacgtca ctgcagcaaa taaagcagat aaaacgggat
    16141 cacctgcttt tcaaattatt caaaataatg tgatcgatgt cagtacgtta ctagcaactg
    16201 acccgaataa agtagaatcc ctaccaacag ataaaagaaa tgctttaaca gcgaaaaatt
    16261 ttaaaacagc gaatatcaat gggattatta ctcctgaaca agctaaaggt atggcaggta
    16321 atgataaaag tgggttatca gatatacaaa aggatcggtt aaaggcatta caataccgat
    16381 tggaactaga tgataatggg aaagaaattc ctgttcaaat tagtgacgaa ggcttagcaa
    16441 aatatgtcta tacttcaggg tatcgtcgat acagtagtaa accaggtatt attttagctg
    16501 gtgaatcttc tttggcagta gcctatttat ttatcctatt tacgatcgtt acttgcatta
    16561 ttgagctggt atttaaaaaa ttctatttag tgattgccgc gtcaacggac tttgagacag
    16621 gtcaacggat gaaaagtgcg atagaagata tttctcaatc cttcttgtta ttggcgttta
    16681 cgattttaga attacgaatc tataccttaa tgctttcagg tatcggtgat ttgcatgcgg
    16741 caggaaagat caatggattc ttgtatgtcg ttgctttgat tgtactaacc attgcgctat
    16801 tcaaaggctc tcaatcagtt acgaaaattt tcggcgttga tacaagcctg aaaaacggca
    16861 gtaattctct tcttagcatg tttgccttag gaaatattgc gaaaaatgtg ggtagcggag
    16921 ctaaaaacct tgcaagtgct ggtaagagtg gtttaagcca tttaaatgat attcgtaaaa
    16981 atggatttgg ccatcgaaaa gatgttaccc ctgataacgg ggaagaacaa tcagacgata
    17041 aagctacaac tgtacctaat agtaagaaaa cagtttccga aatgttcggg aaagcgaaaa
    17101 atggtgtttc taaagccgca gaaggtcttg gttacgtcaa tgaacgtggg ttaaaaggaa
    17161 cagctgaaga tcttacagaa aaagccaaag acaccttaga agataaatta gacggcacga
    17221 gagctaaaga attggctgaa gctgtgaaga atccatccga agcactagaa aaacaaaaag
    17281 aaaaagcttc agaagtcaaa gaaggactaa aagatgcgta tggtgaagga caagtcaatg
    17341 cagcagtgaa agctaataca acaaccgaaa aagaaaatca agaaggtata gtgattcctt
    17401 cagtcaaaga tcaccaagaa gcgttgcact ctaatgaaaa ttcgattgaa gagaaaaatt
    17461 ccatagaaga aagaaattca gaagaaggaa aaaatggaca gttaccaaaa actgatccag
    17521 aacaatatcg ctataaacct aacagtgacc ttgaaaatga gaagcgaatt tcagatttat
    17581 caaaagtaaa tcaagaagac aaagcagaaa atgagggaca gttaccaaaa actgatccag
    17641 aacaatatcg gtatagatct gttaactccg aaaatgaaaa acgcatttca gatttaccaa
    17701 aacgaaatca agaagtacaa acggatgagg attccatcgt tctgccaaat gataatggaa
    17761 tcgaagttgg aactgaaaaa tcaacgaaaa ttggtttacc taaggcacaa aatttaccaa
    17821 tgaaagatag tcgtttgaat caattcaagg ataatgatca aagttttgtt catcaatcac
    17881 ctgcaggtac tgttcaaatg aaaccaagtc gtttgcctga aaatggaaat ctgacaactg
    17941 tttcttacaa tttatctgaa agtggtgaga cagggaatgc gtccgttcaa aatgttgtga
    18001 caagagaagc tgcaccaaaa cctattcaaa acgttcatac aggttacaag ccagcaaatg
    18061 tggcatttac tgcaccaaca aaaataaatg tgacaagaga aacaaaaaac aggaacaatg
    18121 cattgaaaga acaactattg agggatatca aacaggatat caaaccataa aaggcctaca
    18181 agttaggcct tttttctatg tatgaaaagg agaaatcatt tatggataaa tatagtaaca
    18241 tgaaaaaccc tccaagattt agtggagaat ggaagttttt cgcttttttc tttttagatc
    18301 tattaacgct tggtggctgc tttttttggg cgaaaatggt caataatctt gtccacttac
    18361 cactcttttt tgcactcttg aattatggct tatggattgc gatagcgtta gtgattgttt
    18421 ggcgacccta taataaccca ggtcaacgac aaatttttgc gattatcgag tctatttttt
    18481 ttgcggacaa gaaccattat catgcgttag atcctaaccg aaattatcat ggtacgtata
    18541 aggaggatga ataaatgcga gtcaaaggac aaaattcagt tgaaaggaaa tccattttgc
    18601 agtttggaaa accagaagag cgctctatct tggacttatt tccatataaa tcctgtacag
    18661 aagagggagt cttaattact agagaagatc attttcaacg ttattatcgt gtagtttcta
    18721 cagacgtgga aggattaaat gaacaagaga aactagaacg aatgaatcag ttgaccaccg
    18781 tcatgcgtac gtatgtgcca acaattaagt tagttagttt gaccacagag acggatctaa
    18841 cggaacaaat cgtgcaaaag cggcaattat tagataaaaa tcgtatggaa cagtccttag
    18901 gaagaaatct acaacgatta aaaaaatatg aaaagaaatt agtcgaagaa atccaggaat
    18961 tgaaacgagc agaacaagaa cgtcctgact taagcttctt tttcgtcatt gaaggaaaga
    19021 caatcaagga tttacaaacc agaaaccgtc agttaatgcg atctagtggc attttagggt
    19081 taaaaccact ctacaaaaaa gaattgatca agattctgta tcgaatgaac aatatgaatg
    19141 atgagtagga atggagaaga gagaatgaaa tatccgttga tatggttaga aaaagatgtt
    19201 ccgaaggaag agaccactag aaaatttcct cacactttaa gcctgggtaa gttgggaaaa
    19261 gggcaatctt ttaaccaagt aaagaatcaa acaagaagag gtgactgtac atgttagaag
    19321 caattaaaac agctttttca ccacaaaatg atcaaaaagt acttgatcca ttaaagcaac
    19381 taggaaatcg ggaaatagaa attgtaaaat ccaaagggta tgatttagat tttttaaaac
    19441 aagtgatgcc acaaggtggg ttaaattttg atgaagaata tgtgacgtat ggtaatggtt
    19501 attcacgatg tgtgacagtt tatcactaca caaaaaatcc tacgcttttt tggttggcca
    19561 atctcatgaa caatcctcat acagtggcca cactcgatgt tagcacagat gaaaagcaaa
    19621 aagtgattga tcaaatcaat cgtgccttag atgaattaaa tgatcgatca gataatgaac
    19681 gaaaagcgac tgaccgaaat aaaagcgcgg aagaatacct ggaactagcg gaatatgcta
    19741 gaaaattgac ttctaatggg gaaatttcta agcaagtcaa agtgagagta catgtttacg
    19801 gaaacacgat tcaagaagta gatgaacgag cgcaggaact gatcgaaaat ctcaaaggga
    19861 tggattatcg tgcggtgact tatctgcata aaaccaaacg agattggcaa tcgatgttta
    19921 ccatgttcga tgaacaagct gaatggttcg gaaatatcaa agggcaatca ctaccatcgt
    19981 taaacattgg cggaggtttc ccgttccacc accaaacgct aaaagatcca ggagggacac
    20041 aatatgggga aaccatgaca ggcggcccat ttgtctggaa tgcgacgtat aaaaatagtg
    20101 tacggttgtc tactaatacc ttgcttctag gaatgatggg agctggtaaa tcgaccgttc
    20161 ttaaaatgat cgcggaagcc catttagctg caggagactt tatttggggc tttgaaaagg
    20221 gaaaagactt tattcctttc ttaaaggaat ataacggtat tatggtgcgt ttagacggat
    20281 ctgacggaat gatcaatcct ttagagatat ttgccacacg gacgtatgat gaagcatcca
    20341 gtttatatga cgatggatca gtcaaagatt tgaagatcaa tgaagcagcg tcctatcaaa
    20401 cacacttaga caaagtggtc tatcaggtac agttagtgag tcctcagcta aaaggaacga
    20461 tgaaagcaga atttaagacc tacttaaatc gtttttatga agagtatgga acagtaccac
    20521 gcggctttac ttcctcaaat tcgcgttcaa atactgatac gcaagtcaca gggaaagatc
    20581 cagaagctta tccgacgttc aaagaatttt tagacttttt aggacaactg gaattaccag
    20641 gtgcttccca agagaaaaag aatcgaaaag aagaaatgga atccatcgta gaatccttat
    20701 gtgagacgta tggcatgatt tttgatggtc atagtacgat tcgacacctt gaccaacaac
    20761 agttggtctt ttttgacatt gactctatta caggcttaga tcgaggggta caacaatgtc
    20821 aaatgtacat ggctatgacg ttgatttgga atcaggcatt gattcaagga agaagacaac
    20881 gacgtttaat taaagaaaaa caaatggaag aacaagactt caaacgcttc ttggcgatga
    20941 ttgatgagtg ccataatggt gcgacctgtt ctgcagtgaa aagctgtggg ttgcaagtag
    21001 tctaaaaact attgtaataa ctcttataac gagaagtcaa atgagtgggt aacgccacaa
    21061 agggcttcca ctgatactcc gacatgcaac aagtagttta tgcagaccaa cgttgtgtga
    21121 agctcggtga agtcggctga aggataccgt aaggtaaaag aaatagtgaa taccacgaaa
    21181 gttctctaga ggtaaagggt gtatccgata agtcgggtgt ccaaaaaaac ttaatatggt
    21241 gagtatgtac aaacgtactg acgaactagc gaatgtactg tccgaaaggc atagctccta
    21301 gaaatgggag agacagtgag caaaaaatca ctcattgtgc taacttgtgg ttgagtaaaa
    21361 gtcgttgtta tgaaagacca tgctgcgtta caggcgtagg agaagttagg gggcaaaagc
    21421 tagcatctaa gttaaggcat gtggatagat ataagggaac aggggaagcc atcaacatgg
    21481 agagtgcata ctcgatgaag tggtagtaag aaatatgtga atgacaaata acttacttta
    21541 gtgatggtga aagtagagtc acgactgatg aaggttctgt aatggaactg gaggaacagg
    21601 ctcgattcgt ctgtaaaagt catgaaaccc gttcaaccat gggattctcg tatgactaaa
    21661 aaggtcacga gccaattgga gcgtgataaa ccatgacaaa agaaacaagt ccaaaagata
    21721 ggaagttgcg gcatgcagaa tattatggca tgacggaaat cttcgataag atatactcca
    21781 aaagtttgaa gggagataat ttcaagaatc taatgcagat tatcatttct gataacaaca
    21841 ttgtcctagc atatcgtaat atcaagagaa atcacggtag tgtgacaaga ggagaagatg
    21901 gagtaacgat taaagatatt gaaaatctca accgtaatga attcgtagaa attgttagga
    21961 agcgattcgc acattataac cctcggaaag taaggcgtgt agaaattcct aaatataatg
    22021 gtaaattaag accgttgggt attccatcaa tatgggatag aatcgcgcag caatgcatct
    22081 tacaagtatt agaaccaata tgtgaagcaa aattcaataa tcacagctat ggtttccgcc
    22141 caaatagatc agcagaacac gcaatagcag attgtatggc ccgaatgaat caaagtcaca
    22201 tggaatatgt ggtagatgta gatatcaaag gtttcttcga cgaagtcaat catactaaac
    22261 tcatgagaca aatctggtct atgggtatac gagacaaaca gcttctctta atcattagga
    22321 aaatgttaag agcacccgta gtacttccaa atgggaagtt gatataccca acaaaaggaa
    22381 caccacaagg cggaatactt agcccattac ttgcgaacat caatctcaac gaatttgact
    22441 ggtggatagc aaatcagtgg gaggaaaaag atgccaaaga gctaaaacat cattttagga
    22501 aaaatggagc ttgggataaa ggtaatatct atcacaagct cagaaagagt acaactctaa
    22561 aagaaatata cctagtgaga tacgcagatg attttaaaat tttctgtaga aattataatg
    22621 aagcgaaaaa agttttctat gcaactaaaa tgtggttaca ggagcgtcta aagttaccaa
    22681 tatctgaaga aaagtcaaaa atcacaaatc tttcaaaaga agaaagtgaa tttttaggct
    22741 ttacgatgaa attagtgacc aaaggtaaca aaaaggttgt taatacgcat ataggtacaa
    22801 aagcacaaag catgattaaa gtgaaactaa aaaaacaaat caaacgaatt caaaaaagtc
    22861 ctaatagcaa agataccttt atctatattg gagtctataa cagtatggtt attgggattc
    22921 ataattactt caaaattgcg actcattgta gtgtagcaat gcgaaaaatt gcaagagaac
    22981 tcagaccaag ttttgaaata cgactacgag aacaaggaat ctcaaaagaa ggacaatacg
    23041 gaaagtacga aggatacaag ccttacctac ggtcaggaca aatacgatat ataagagggt
    23101 ttccaatatt accagtaggg tatattcaac acagacatcc gatgtgtaaa aaaagaaata
    23161 ttaataaata caccgaagaa ggtagggaag ccattcataa gaagcaacaa accgtagaag
    23221 aatggaagat atcgtggttg tgtagcaatc cagtgcttag taagagagca acgattgaat
    23281 ttgcggacaa tcgaatttca aaattcatcg ctcaaaaggg aagatgtgca gtaacaggtg
    23341 aggagcttat cttatctgaa atgcattgtc atcatattat cccttatcat gaaagcaaaa
    23401 gtgatagcta tgaaaaccta gtgattgtta ctgaggaggt tcatcgggta atacacgcta
    23461 cacaaagtga aacgattgag gaacttctaa aatatctaaa attaaatcca aaacaaaaag
    23521 aaaaactcaa tgagttgaga ttaaaagttg gtaacgaaga aatatcttaa taaatatttg
    23581 taggacggga aaacagaatg tcttttatag acgagggaac gccgtatgcg gtgaaagtcg
    23641 cacgtacggt gtggactggg ggaaaagacg gagataatat caaactctta cctatcagta
    23701 tcgattaatc cagattttat tgaaacggta aattatgtca caaactttca acgagaaatg
    23761 cgtaaagtag aagcaatgac tgttttagct acacaatccc cacaagaaat ggtgccagaa
    23821 aatatgtctt ctgataactt ctcgaaactg aagaaagtct ttgaattttc ttctacgaag
    23881 atctttatgc gtatggatga atctatttta cgtcatatag aaggattagt gggtaaatca
    23941 atgacgaact cagaattaga atccattcct caacaaaatc aaggagacgc tgtgatcaat
    24001 tttggctcaa aagaaaccat tcgtgttcat tttagtccga acaaacgtca attaaaattg
    24061 tttgatggag gaaaataatg gaaaaccaaa atgaaagttt aatcaagcag tatgttaagc
    24121 gtcgtgcaaa gcggcgctta tttttgtggt tgtttggtac ttctgcaggt ttgattacta
    24181 ttttgatcac tgtgttcgtg accctatttc taatacttgc ggcgggctcg attgataatt
    24241 cggattcaga ttcaagcagt ggtggcgaag cttttacagg agaatattcg gaaggcttac
    24301 cgatttataa agaaatcaaa ggaagaggcc ctttttctga tgagattgcg caatatgccg
    24361 taggtgcagc agtgaaatat aaattattac caagtgtgat cctttcgcaa tacggttacg
    24421 aatcagcgtt tggtacatcg gcgtccgcaa gaaatgatct caactatttt gggattactt
    24481 ggtttgatgg ttgtctgttt cctaaaggaa ctgcacgagg aattggtggc attgaaggtg
    24541 gctggtacat gaagtttccc aactcaaaag ctgcattttc ctattacggc tttatggtag
    24601 ccacacaatc caattttaat gcttgtgtag gaaataaaag ccctggcgca agcttattga
    24661 tcttaggacg aggcggttat gccgctgcag gaattactga agacagtgcc tattataaaa
    24721 attgtatgtc tattattaat acaaataaat tgatggagta cgatgagttt gcgattaaac
    24781 actggagaga aggcggcgga actggtggta cgattacagg aagctggggc aatccattcc
    24841 caggaagtag cttagataaa aattcgttca gtggaggaca actttttggg aaaaatccag
    24901 gaggagaatt ccgacctaac gggttccatg atggactaga ctttggttca gtcgatcatc
    24961 caggaagtga gattcatgcg gttcatggcg gaaaagtcgt gtacgttggc aatcctggta
    25021 tttcaggttt gggtgcgtgt gtgatcgtga ttaattacga tggcttgaat atggtgtatc
    25081 aagaatttgc aaatagtaca ggaaattctc gagtgaaagt aggcgatcaa gtgaaagttg
    25141 gtcaagtaat tgggatacga gatacagcac acttgcattt aggatttact cgaatggatt
    25201 ggcgtcaagc acaaggacat gcattcattg atgatggtac atggatcgat ccgttaccat
    25261 ttttgaatag cagtaaaaaa tagatcagga gaaaaaatat ggaaaataaa acgttaaaaa
    25321 tcgtcttaac agctgcaatt agcgttagtt taatcggcaa tattgcgttg ttttggcagc
    25381 tgaaagagga acaagcagca aatacctata aaattgaaga agtggctaaa aacgcgtctg
    25441 agaagctcaa aaaaaattcc tctgaggcac aggcgaagat cgacaagtta aatcaaacca
    25501 tcaatgagaa aaaccaagaa atcgatcagc tgaagcaaca agatggcaca aaagcaaaag
    25561 aggaagtaac tgaagcacaa agaaagacgg cagaagagtt cggtcaattg gccattgata
    25621 aatcattaag cagaaatgaa ttaacggaaa aactaaaaga tgtcgcaacc caagaagtga
    25681 tcgacaaatt aagtcctaca gacgatgatc accaacatga tgattacgga agttactcct
    25741 ttacattagg tgacgtgcaa acttacgctc aaacaagcag tgtaaaagag gaacaaaatt
    25801 ttgtcgtatt tgttgattat acaatcggca atccgcaatt caaagatgtc aaaccacaaa
    25861 aaataaaagg tggattaact gtcactgaaa aacaagtaga tggtcaatgg aaagtcatag
    25921 actttagtta tttcactcgt taggaggaag aaaatgagta agaaaaaagg agaaagacaa
    25981 cgtttcaaaa aacgaaaaag ttatcttaga tggctgggaa tctttatgat tctcggcttt
    26041 ttgattcttg ctagtccgat ttatacgaat cagaaggtag atataccaga tgaggtaagc
    26101 acgaacgcct ttttaaacac gaaagagctg acaatggttt caaaagaaaa aggagcgaac
    26161 cagcaattag tttttgaatt tgcgatcgat gatgaagatc aaagcttgtt aaaagaactg
    26221 gctaatctta attatcgcgt agaagtaaag acagctaaag gggattatca agcaatacga
    26281 gccaaagtga ttaaggtgtc tgatgattat tttgcagtga agctaacgca tgtaccagaa
    26341 gaatatatcg ccatgcgttt aaccattatt cctgaaaaaa ttgatccaaa agtggatatg
    26401 caagaaccac aagatctgat ttattacgtg cacgaagata aggttaaaga tcaagtgaaa
    26461 gacgaagatt atgaacaaca cgcgatcaat tacaaagtga aaggatacaa gaaagaacaa
    26521 aaagcagctc aaaaacaaat ggaatctttc caagcaacca ttgatttgaa tgaagaatta
    26581 gtgaagaagc taaaagatca attgccttat caagtcgcag atgatcagga aaatactgaa
    26641 aacaagatta atagctacca gcaagaaatt gaaacatcga aaacgcaact gaaagatcaa
    26701 gaagagatca ttcaaaaact tcaagaaaaa attgatcgta tgacaaaaga aaagatttag
    26761 aaggacaggt ggagtgaaaa aatgaagcga acaaacttgg ctgacaaaga tactttcgct
    26821 gagcagaaag tattgattaa agcctatctc aaagttgtaa aagctaaaga aatatgtcaa
    26881 gaagtgaatt atctaacaca acaatatctg agttgaagaa tggtagaaag agtttagata
    26941 ctttaaaatt cagatcattt gaagctctat atgtagctgc taaaaaatat tttacagctg
    27001 ataacaaata aaaaacagga gtattttatg tgaaaaaagt atataaaaaa tgcttatgaa
    27061 tcagctatat caccttaacc atttgttaat gagatgggag aaaacattaa ccacgattct
    27121 aacgcaaaca tcaagcacat aaaacattta acactcctcc tttctggctg aagatttcaa
    27181 ccaaacagga agacagcgta tcaattatag catacacttt ttcttaaatt catttttcat
    27241 atgacaaaat atttccttct aatcgacaaa gttagaagga ttttttattg tctaaataca
    27301 caaataacct taatttttaa agagcataag gaaacgtgat atcactttct cacgaaaggt
    27361 gttaggtagg ctgtgcctac cacgtttcta agaaagataa atgatatcaa aattttggat
    27421 ttgtgtgtag atttgtgggt aggatgaaag cgaatgtggg cagtaaaata agcgtttgtg
    27481 tgtagcaaaa tcaaaaaatg tgtagggata tgtgtagcta cacatatccc tacacataat
    27541 aaatttggag gaaaatatgg acttattaat tagaaatatt gaagaaaagt atattaataa
    27601 aattgacaaa cgttgtgaag aacttacggt caagactggc aaaaaatgga gtcgaaatca
    27661 atacctaaaa gttttgatcg aaaatgattt tgatcacgct cttctgaatt ataaaaaaga
    27721 ccaatttgat cggttgttag aaaaatttgt ggatattcaa acttataata cgaaaacttt
    27781 agaagaatat attgcaacaa ataatcaatt aattggtttg ttaattgaat aataaaaata
    27841 gtattgtgaa tttataaaag gaggaaatca attttggcaa aagcaacaag aaaacatgta
    27901 tatctttacg atatgcatat cgaagtactt gatgaaataa tttctactca tgaagatata
    27961 tctaattata gtgaagcagt cagacatttg tgtatgatgt atgatccaaa aatcgaagaa
    28021 aaaataaatc caattcaaat taaattgaat gcaatgggaa aagaaatttc tattttaacc
    28081 gaaatggttt cagagtttgc ggatcttcat ttgaaagata caggaatact aattggtaca
    28141 aattcaactg tttatcaaga agcagaagaa cgtgtggaag gaaaaattaa atccaatcaa
    28201 accaaaaaat attcttctaa gttaaagaaa ccagtgaatg aatctgttca taccagagta
    28261 gatccatttg atccaacgaa gattctaaaa agataaaagt agaaggagaa cgtgatgaat
    28321 aaatcgcctg cagttattct tacttgtcaa tttaccttgc ccaataaaaa atctttttca
    28381 acatacattg attatatgac aagagaaaaa gcactggaag aaatggaacg acgtacgccc
    28441 gaagaagaac aggaactgca acgaatcaag aatgctttag aggattttta tattcctgaa
    28501 ggagaaactt tttcggaaag taagacggat aaagaattca gtgaaacgtc gaatgaagct
    28561 caatcgttga tggaacatgg aatcaatttt gacaagttag aggaacaaga ttttaccaaa
    28621 tatctttctt atatgacccg tcactatgcg ttagaacaaa agaaagaact gacgcaaagg
    28681 gaacaaaaag aataccaacg gttgaaccaa gcaatgaaaa aatatcaaac agagccacat
    28741 aaaaaagctt caggaaatct tcctggagtt ttttctatgg cttcagacga agtgaaagga
    28801 agtgatctga aggagatcaa acaaatcttc caaagaggac aacaaaaagg ctcaatcatt
    28861 tatcaagatg ttatctctca cgacaattcg tatcttgaaa aaatgggctt gtacgatccc
    28921 aaaacagata ccttagatga agaaggtttg aaagcagctg gaagaaaaat gatggagaca
    28981 ttattcgaga aagaacaatt gaatgaaaca ggttactgga tggcaacgat tcaccgtaac
    29041 actaagcata tccatattca ttttgcagtt gttgaaaaag aaaatacgcg taaaccgtat
    29101 actgagattg aaaatggtgt gagttatatc gtaccgaagg ggaagagaag acaagcaaca
    29161 ttagacgcaa tgaaaaccaa ttatgtacat gagttagaac gtttctctta tgaaaaggat
    29221 cgaatgatcg gtatggagaa acgaaattta ttgacacgaa aaagtgattt gcgtaacacc
    29281 ttaacaaaag tagtaaaaga accagcacgt tacgatcgac acgccatgaa cttattaaat
    29341 gaagtatata aaaccctacc tgaaaaacgt tcggaatgga attatggaga tgaaaatcga
    29401 accaagcttt caccatttac aaggggaaaa cttgatgagt taaccaaata tgttttaaca
    29461 aaagaacctg gatatcaaga atatatacag atttcaaaag cattgaaaga agaagccaaa
    29521 agcctttatg gggaaagcaa aagagaaaca aagaatgcag aaaaaaacgc cctctttgat
    29581 ttaaaaaagc gcacaggaaa tgcgatttta acagaactga agagacagga tagtcaaata
    29641 aaaccattaa tagaaagtgt caatcagatg caatctattt acaatgaacg atcctttcga
    29701 acactcaaac agttgccaac aaatgaatac aagtatagtt atcaagaatt cgtaaagcgt
    29761 aggaaacaat tccaacaaag agttgtcacg cagcgaagct tgcgtcaatt aaatcgaaca
    29821 attaatgcac atgaagaaaa ataccacgca agtaaagcat atgaagagca acagcgaaga
    29881 atccaaatgg aacaagaaag acaataggag gaagagaaat gaaacaatat ttagatcaat
    29941 ggaaagtcat agaaggatca ctaaaagaag aacgaatcga acaacttcct gattgtttag
    30001 aaaaagagca tttgtttcag ataagcgaaa tgttgagaaa cgaacagttt gatccaaatc
    30061 aatttttagt tgttgagtac ccagctactg gtgtgtattg ttgtaatcat gtgaagggtg
    30121 aaaaatattt tattattcaa gaatacgaag gtaagttagc gccttattat actacttggg
    30181 aaataaatga agagggaatc aataatttcc catgtgaaag cattgaagag tctatttctc
    30241 tcacggaatg ttaaataaat agagacgtaa aagagtcctg aacgtgattg tccaggactc
    30301 tttttcaatg aattgttttc cgccaattca ctgagtggtg cgattcaatt ttattatatc
    30361 aaaagaaagt gagattccaa agtgaaggga ggaagaagaa atgactcaga caacgattgg
    30421 tgttgtggtt gaaaaaagca gggataatct cgtttttgtg acagaaattc aaacaggtag
    30481 agcttttgta gtcacagaca aagctgcaaa agcgtatcaa aatggcaata ttttaacgtt
    30541 aaatctgact acgaagatgt tcgttgatgc agtagaaaat tatccatttg tttagacaaa
    30601 cgatatttta caaggaggaa acggacatgg cagaagaaaa agaaccacta gataatagtc
    30661 ggttgggaaa gtccaaaaga aaattagtac ggttgcaaaa cgaattaaat aatcaatttc
    30721 aaaagctatt tgatcaccaa aaattgacaa atgggcaacc aatgaatgac aaacgaaatg
    30781 gtcgttcatg gtttaaccag caagaaaaaa tagaaaataa aatacaaagt ttgagagaag
    30841 agatcaagca acaagaaaaa caggtagaaa aacttgaaag acaagaagag ctaaaggaaa
    30901 tgggctataa caagtacggc ggactggata tgacgatcga taatattcca agaatcaaag
    30961 aagaaatcga acgctttgaa aaaggtgaat cgactttttc agccgccacg atccgaaaat
    31021 atcaacggaa gttggaaaca ttagaacagc tgaaagaaaa atcagaaaaa ggaaaagaaa
    31081 atatcctccc tgaagtacaa gcgatcattg acagcggacg agtgacgcaa tggaaaaaaa
    31141 atccaaccat ttattttttg aaaggctatc gaaaagttgc tttagaactg aatgaaaacg
    31201 ggggatttga ggaatcaaaa aaataccaag ccacgtcgga agaggaaaaa gcagctgttc
    31261 gtgaattact tgaagaggct gcaccaactg attctctgaa ggagaaagaa aaagatcatt
    31321 tctatcgagt agaattcaac gaaaatgatc cagaaaaagg attgaaaagt tatggtgggg
    31381 agatcgtaac attagaattg atcgatcaac ttaaaacgtt ggataaccaa tacgctgcag
    31441 aagcaggtta ttataaattc tattttgaag aagtgaagaa cggagaagta gtcgatcaga
    31501 tccgaatgga tctaggggat ggcgtcaaca gtaatcaccc catctattta gagttagcaa
    31561 aattgtgcga acaagtacct gagaaggaac aaaaacaatc ggtcaaaaat gaacctgttt
    31621 cgaaagaaca aatgcagtcg aaagaaacaa aaacaaaaca aaagggctat caaaaacgaa
    31681 cggcagaaga gatcaaacaa gaagttaaat ccctttcgca acaggcactg gatgcggtga
    31741 aaaagcatac ccattcttct gaagacgtca aagaactttt gaactttatg tctcgttttc
    31801 cagaacgatc ctttagaaat caattattga ttgaggaaca atttccaggt gcaacggctt
    31861 gtttaggtcg tgccgcgttg aaaaaagaag gaatctatat caaaaaaggg gaacaaggga
    31921 acaagatctt tgtcagaaaa acggtcaaag gattttatga gaaaggacgt ggctttgttc
    31981 gagaaacaga agctacacca gaagataaaa aacgaatcga aagtggtcaa atcgaagtga
    32041 tcaaaaaa
//
LOCUS       DAZKNV010000030        31910 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000030 DAZKNV010000000
VERSION     DAZKNV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.030"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(269..802)
                     /locus_tag="ACG8M1_001543"
     CDS             complement(269..802)
                     /locus_tag="ACG8M1_001543"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFQ0422262.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(1666..2418)
                     /locus_tag="ACG8M1_001544"
     CDS             complement(1666..2418)
                     /locus_tag="ACG8M1_001544"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFQ0422263.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            2531..3451
                     /locus_tag="ACG8M1_001545"
     CDS             2531..3451
                     /locus_tag="ACG8M1_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0422264.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3524..4459
                     /gene="murB"
                     /locus_tag="ACG8M1_001546"
     CDS             3524..4459
                     /gene="murB"
                     /locus_tag="ACG8M1_001546"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFQ0422265.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            4757..6235
                     /locus_tag="ACG8M1_001547"
     CDS             4757..6235
                     /locus_tag="ACG8M1_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422266.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            6512..8572
                     /locus_tag="ACG8M1_001548"
     CDS             6512..8572
                     /locus_tag="ACG8M1_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFQ0422267.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            8655..9224
                     /locus_tag="ACG8M1_001549"
     CDS             8655..9224
                     /locus_tag="ACG8M1_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422268.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(9399..10205)
                     /locus_tag="ACG8M1_001550"
     CDS             complement(9399..10205)
                     /locus_tag="ACG8M1_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422269.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            10343..11857
                     /locus_tag="ACG8M1_001551"
     CDS             10343..11857
                     /locus_tag="ACG8M1_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFQ0422270.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(12260..13243)
                     /locus_tag="ACG8M1_001552"
     CDS             complement(12260..13243)
                     /locus_tag="ACG8M1_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFQ0422271.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(13248..13895)
                     /locus_tag="ACG8M1_001553"
     CDS             complement(13248..13895)
                     /locus_tag="ACG8M1_001553"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFQ0422272.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(13980..14612)
                     /locus_tag="ACG8M1_001554"
     CDS             complement(13980..14612)
                     /locus_tag="ACG8M1_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0422273.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(14628..15179)
                     /gene="coaC"
                     /locus_tag="ACG8M1_001555"
     CDS             complement(14628..15179)
                     /gene="coaC"
                     /locus_tag="ACG8M1_001555"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFQ0422274.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(15176..15913)
                     /locus_tag="ACG8M1_001556"
     CDS             complement(15176..15913)
                     /locus_tag="ACG8M1_001556"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFQ0422275.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(15910..16899)
                     /locus_tag="ACG8M1_001557"
     CDS             complement(15910..16899)
                     /locus_tag="ACG8M1_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFQ0422276.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            17157..17699
                     /locus_tag="ACG8M1_001558"
     CDS             17157..17699
                     /locus_tag="ACG8M1_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFQ0422277.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            17716..18801
                     /locus_tag="ACG8M1_001559"
     CDS             17716..18801
                     /locus_tag="ACG8M1_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422278.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            18813..19619
                     /locus_tag="ACG8M1_001560"
     CDS             18813..19619
                     /locus_tag="ACG8M1_001560"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422279.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            19620..20447
                     /locus_tag="ACG8M1_001561"
     CDS             19620..20447
                     /locus_tag="ACG8M1_001561"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422280.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            20444..21517
                     /locus_tag="ACG8M1_001562"
     CDS             20444..21517
                     /locus_tag="ACG8M1_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422281.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            21945..24641
                     /locus_tag="ACG8M1_001563"
     CDS             21945..24641
                     /locus_tag="ACG8M1_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0422282.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            24706..25206
                     /locus_tag="ACG8M1_001564"
     CDS             24706..25206
                     /locus_tag="ACG8M1_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0422283.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            25218..25712
                     /locus_tag="ACG8M1_001565"
     CDS             25218..25712
                     /locus_tag="ACG8M1_001565"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0422284.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            25733..26542
                     /locus_tag="ACG8M1_001566"
     CDS             25733..26542
                     /locus_tag="ACG8M1_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0422285.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            26539..27360
                     /locus_tag="ACG8M1_001567"
     CDS             26539..27360
                     /locus_tag="ACG8M1_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0422286.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            27411..29510
                     /locus_tag="ACG8M1_001568"
     CDS             27411..29510
                     /locus_tag="ACG8M1_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFQ0422287.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            29507..30625
                     /locus_tag="ACG8M1_001569"
     CDS             29507..30625
                     /locus_tag="ACG8M1_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFQ0422288.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            30664..31542
                     /locus_tag="ACG8M1_001570"
     CDS             30664..31542
                     /locus_tag="ACG8M1_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0422289.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            31688..31885
                     /locus_tag="ACG8M1_001571"
     CDS             31688..31885
                     /locus_tag="ACG8M1_001571"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFQ0422290.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
BASE COUNT        10248 a         5505 c         6617 g         9540 t
ORIGIN      
        1 ggtaaacggt gtccaaaagc ttgcatctgc ggtaataagt ccaaccaaat gaaaaatatg
       61 agaagctatt tttgtttggc tgttcttatt acttgatgca gaacagcttt ttcacaacct
      121 ctccaataaa cggtgttctc ctgccagctc ctcggtcacc agtcacaata tttaataaac
      181 atgagaagct attttttgaa attgctcctt gtgactcgga gtgaaacggc aggctcacga
      241 cctctttgtg tgtttcataa gtattctttt actttatagt cacaagtttt ttcaatggat
      301 ctgtcccgaa ttttttttct tgataaagca ggatttccgc acatgcacga ctatcttcca
      361 atgcatcatg gtgatgatct aattggatgt tcaaattttc gcacacagtg ttcaatcgat
      421 gatttggaaa ttcaggaaac aggcgacggc tacttttcac tgtacataaa gaaagataat
      481 taggctgttc aagatgataa taatctaagc atcccgctaa gacctttgta tcaaaagcag
      541 cattatgtgc aacgactaaa cgattttttt gaaaatatgg ttggatagtt tgccagactt
      601 ctgggaattt cggcgcattg cgtacgtctt cttgatggat tccgtgaatt tggacatttc
      661 gccagaaaaa aggagtctca ggctgtatca atgtatagaa ttcatcaacg atctggctat
      721 tttttaccat gactagcgca agagaacaag cactataagg ctgatgattg gcagtttcaa
      781 aatccatggc aacaaaattc atttctgtaa aacctccttg ggaaattact gtaacatact
      841 tttgaaaaaa gcaaataaat ttaacaaaaa acatagaatt ttttatgtaa tatttgttga
      901 gaaaagctag tttttgaact cattccttgt gatttggagt tagatgggga tcatgacttc
      961 tcggtattaa gtcaaattta tgcaaagttg tgaggaacca ttttcaaaaa aatttcttac
     1021 gactcgaaag taggcgactt tttcacaact tctccactaa acggtgttca atcagctgac
     1081 cctcggtatt agctcaaaaa atagcaaaat atgaggaact attttgccat ttgtttctct
     1141 aatactcagg tcaggacgct gatttcacaa cttctcaata aacggtgttc aaaagcttgc
     1201 atctgcggta ataagtccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
     1261 cttattactt gatgcagtgc agctttttca caacctctta ataaacggtg ttcaaaagct
     1321 tgcatctgcg gtaataagcc caaccaaacg aaaaatatga ggaactattt ttgtttggct
     1381 gttcttatta cttgatgcag tgcagctttt tcacaacctc ttaataaacg gtgttcaaaa
     1441 gcttgtatct gcggtaataa gcccaaccaa acgaaaaata tgaggaacta tttttgtttg
     1501 gctgttctta ttacttgatg caggacagct ttttcacaat ctctcgataa acagtgttca
     1561 aaagccagtt tctcggtatt atgccaaatt tatgcaaaat gtggaaagcc attttcacaa
     1621 aatttttctt aatactcgaa actaaacgac tttttcacaa cctctttatt tcaaatctaa
     1681 ttctactgga caatgatcac tgcccataat gtccgtatgg atctttgcat cagctagtcc
     1741 tggctctaaa tctttgctcg tcaaaaagta atcgatccgc caaccagcat tgtttttcct
     1801 tgaattgaat cggtagttcc accaagagta gacaccttcc tgggttggat aaaaataacg
     1861 gaatgtatcg ataaacccgt tatccaacag tcgagaaaga gccgctcttt cttctggagt
     1921 gaatccagca tttttttgat tcgttttcca gtttttcaaa tcaatctttt gatgagcgac
     1981 atttagatcc ccacacacga tgactggttt ttgttttttt agattttcca aataattata
     2041 aaaggcttct tcccattcta atcggtaatc taaacgtttt aattcgcttt gagaatttgg
     2101 cgtgtaacag gttacaagaa agaaatcgga atattccaaa gtaatcagac ggccttctgt
     2161 atcatggata tcgataccca ttccgtaagt ggcattcaat gctggttttt tagcaaaaat
     2221 cgctgtgccg gaatagcctt ttcgttccgc gtaattccaa tattgataat aacctggaag
     2281 atctaaatca atttgtcctg cttggagttt cgtttcctgc agacagaaaa aatcggcgtc
     2341 taactcatga aaaacttcta aaaaattttt atttacgatg gcacgaagcc cgtttacgtt
     2401 ccaagagata aatttcaata aaagcacact ccttcgaatt aatttcctta cctttgcgat
     2461 actattgtac ctcattttag taaaaaatgg tgtaagatga aagtaactaa atgatccagg
     2521 aggaaagtag atgaagattg gtgtaatcgg tgtagggaat atcgcagaaa aagcatattt
     2581 accaacttat gcgaaaaaac aaggaacact tgatttttat tttgcaacaa gaaataaaga
     2641 aacaaaagaa agaattcaaa aagagtacgg gttccaacat ctatatgaaa cgatcgatga
     2701 gcttttagaa gaaaaaatcg aagcatgtat gatccacgca gcaacaaaag tacattatga
     2761 attagccaaa aaatgtctag aaaatggtat ccatgtttat attgacaaac cactgagtgt
     2821 ccatctaaat gaagttcgtg aattgcaaga attagctgat aagaaccaaa taattttgat
     2881 gatcggtttc aaccggcgct ttgctcctat ggtagaagaa ttgaaacgta tcccagataa
     2941 gcggttgatc cacctgcaaa aaaatcgaat agcggcaaaa gaaacgacag agttcgtcct
     3001 ttatgatttg tttttacatc ttattgatac agctgtgtat ttattagatg aacccatttt
     3061 gagaacaaaa taccagataa gagaaacaaa ggaatttttg gaatatgcca ttttacaatt
     3121 agaaacacaa aatcaaacgg ctattttaac gatggattta gcaagtggcg ctaatataga
     3181 aaaatatcaa gtaacaagta aaaatggtac ttatgaagta aacgatctga cccagcttgt
     3241 cattcaagat gctgatggaa aaaaagtgaa agaatttggc gactggacaa acacgctagt
     3301 caaacgcggg tttgagccaa tggtagaggc cttcttttct cagatccgtt taggtaaatc
     3361 ggaaacagaa ttgcttaaac aaaaagaagt tgtaagaagt catgaattat gtgaggaagt
     3421 gcttaaagat cactaccgtc atcaactttg aacaagactg gcaagattgt attaagcgtg
     3481 atagaataat gaggacgttt gagaaaagaa aggaaaatcc tcagtgaata aagaagaaat
     3541 agttgaaagc ttagccacga ttactatatt gtttgatgaa ccattgatga actatacgtt
     3601 tacgaaaaca ggtggaccag ctgatgtcct tgcattcccg aaaaaacaag aagaagtaaa
     3661 gcaaatcatc gattattgcc gaatccatga tataccttgg atggtattag gaaatgcaag
     3721 caatctgatc gttcaagatg gcgggattcg cggtgtagtc atcatgctga ctgaaatgaa
     3781 acagattcat gtcaaaggaa cgatggtcat tgcggaagca ggtgcctcac tgattgatac
     3841 gacttatgca gctttggcag aatcattgac tggatttgaa tttgcttgcg gcatcccggg
     3901 aagtgtcggt ggagcggttt atatgaatgc aggtgcgtat ggcggagaga tcaaagatgt
     3961 ttttgctgaa gtggatcttt tgcttgaaga tggaacattg aaaactttga caaaagacga
     4021 aatggtattt tcttatcgtc acagtaaagt ccaagaatta cgtgctatcg tattggaagc
     4081 tcgattcagt ttgcaaacag gggattatga agcaatcaaa gcaagaatgg atgagttgac
     4141 cgaattgcgt caatcaaaac agccattaga atacccttca tgcggaagtg tctttaagcg
     4201 cccagtagga cactatacag gtcagctgat ccaacaagca ggattgcaag gcctgaaatg
     4261 gggcggtgca caagtctctg aaaaacatgc tggattcatc gtcaatatcg atcatgcgac
     4321 agcgacagat tatattgaat tgattgcgca catccaagaa gtaatcaaag aaaaatttga
     4381 tgtgtcttta gaaacagaag tgcggatcat tggagaaaaa caagcaatat cagaaacaag
     4441 cagaagttta gccaattaat aagtaatgga acttaaaata agtaaaagag caggacggtg
     4501 gccgtcctgc tcttttttgt ggttgtttac gcaaatggcg caaatcttgt acattttaac
     4561 acaataaaac aaaaaatata gaatatttcc tcataaattt ttccattttt tgcaatattc
     4621 tcaaaaaaaa gataaaaaat gagaataact gatgaaaaaa caagcataat ccatcataaa
     4681 atcagtatag gtgaaaagat gaactttcat ctgcatatca agtaattggt atgaggcatt
     4741 ttttgaggtg taggatatga agttggatta ccttatagaa gaggaagata gagaaaaact
     4801 gctgctagct agatatttag aatttgagaa aaagaattat gtagtgctgc ctaagttata
     4861 tgaaacatta ggtttgtcta aatttaaaac aagaaattat atcatagaat taaataaaga
     4921 atttactgaa ttcaaaacaa agccagagat ccaaatttca gaagaagcag agatccatgt
     4981 cgaacgtctg aatttgacgg atatcaaaaa tttaagaaga atctactttc aacgatcaaa
     5041 aattgctcga ctgttaacgg agatcgtgga ttcaaaagta acgatcgaaa aatttgcaga
     5101 gaatcatttt ttaagcatat caagagccta tgtaaaaaga agagaattag tctcttttct
     5161 tgaacagcat caaataaagt taaagaaaaa catattagtt ggggaagaaa taaacatacg
     5221 gaacgtatta tttggggtat atttcggggt ctttaatggt ttttctatgc catttagaga
     5281 aagcgtcatg aatgaagcaa agagtatcgt gcaatatttt gaatatctgt tcaatttaaa
     5341 actgtctgca acaaaacgaa tcaaattcaa tttgctaacc actattagtt tgttgagggc
     5401 ctatgggaat caaccaatcg gaaaacgttt cttttcagat gaatacttta agagctcaga
     5461 aggaatgaag atcatcaagg atttatcaca tatttctttt cttcatatcc ctaaagagca
     5521 gatcattgat gagatttctt atatcatgtt gtttttgatc acggaagaag aatttgaatt
     5581 agatggcgca tttggacttg cggaagctca ttttcatgat atccacatga ttagtcaaaa
     5641 aatgtcagtg gaattgattg atcaattacc attttcgatt gaaatctctg aagaagaaag
     5701 actatatata cgaaaagaac ttcgtatggg tatgatgcat gtcaatcgaa aaaattggat
     5761 attcgacttt gagatgacta gctttacgtc taaaaagcag ctacagtttt tcttcgagac
     5821 gtatccaata ttcagtacag caatccaaaa ggtcatacaa gagaataaac gctatttctt
     5881 gggaaaagat gaacgtttca tgattcgctt attttatgat tatctctttt tattggtcgg
     5941 tatttgtccg gtatcatatt ttgaagcacc gattcatgtc tgtattgatt tttcgcaagg
     6001 atctgcttat accgattaca ttatttctca agtgaaagga tttaaaaatt acaatattgt
     6061 gattgagagt cgaatcactt ctcgtacgaa tatttattta tctgattgtt tacttgaaaa
     6121 atttaataaa gaacagataa tttggaaaaa tccaccgact ccagatgact gggaatattt
     6181 tggaaatacc atcatcagag aaaaaaatag acatttaact gaaaaaatca gctagtattt
     6241 atggatggca gctttgtctc acatatttat tagctgattt atgttttttt caaagaaaag
     6301 gtaactagat ataactagat ataactagat atattactta acaaaattaa aaagtacata
     6361 agttattatt ccgattttct tgaaacaata aaaaatcaaa aaaaatactc tcctaatagt
     6421 ccatcttctt ttgattttat ttatataatg aaatcatctt atgaaaatta ctacttcatg
     6481 tttagacaag agtagggagg actaagaata aatgtgttca aaaagacgtt caaaacaact
     6541 aaataaacac gcttgtcgtt tagataagga acggtcgtgt tctgaaaaac actacgttaa
     6601 gtttatgatg cgcacgatgc tgatcagttt atctgtaggt gtctatatgc atgtacccgt
     6661 tcaggcaacg acacaaacca tcaaggtcgt acgtacctct gtttctgaga ccactgattc
     6721 ccctatcact attactcata ctttcactga tgcaaatgga aaacagctac ttcctgcatt
     6781 gacttcctat aataaagtca gttatcctcc aacgataaac cactactggt taattcctaa
     6841 caaaacatta tggacatcgg aaaccggaag cagtgtgccg ctttctatct tttccgatat
     6901 gactgatcct acaaaaggtg atcagttaaa acagatcact gatattttga atcatgcttt
     6961 gacagatata aaggacggtg gaagcgcaca agtttcttat gtatatgaaa aagattattc
     7021 acagtttgaa agaaagaaaa tcgatgttct ggcagggaca aaagtttcga tatctgatct
     7081 ggtagaaagg ctgaagaacg cagatggaac acaaggagat atgtccaaag taatttcaaa
     7141 caatgggaat atcgtggata cgactaatac aggaacatct actatttcct tgtcctattt
     7201 tgatccaatt gctttaaaaa caatgactgc atctgctgtg atccatgttc gtgctgatca
     7261 aacagctatc aaaggaaaag atcttcactt aagaacagga gagagttacg cccctaaaga
     7321 tcttgttgaa tatgtaacaa aaagcgatgg aacttcagga aataaagaag aaatcaaaat
     7381 gaacgggaca gtagatacta caactccggg agaatatccc gttgtattaa cttatataga
     7441 ctcgaaaaca tcaaatgtgg cagaaacaac agctgtagtt tatgtagaag catctgctgc
     7501 ttcatcgact gtcatcactc attttataga tagtcaaaca aataaagaac ttcaagcaga
     7561 aacacatatg agtagtgtaa atcgtattcc tgatttgcgc ctacctgctg aattttctga
     7621 tcgagtgcca aatatagatt tatcgactta tgaacaaaat gggaaagtca cttctatttc
     7681 tgattggatg caagcaaacg gattagacag aaaaagtcac tggtcggaga tccttgaagt
     7741 acttcactca gaactgatga ataataggaa gcaatcagga ggggaaatta cctttactta
     7801 tgtttatata ccagacaatc gttcattaga aggtcatgat cttattgttc atccaaacga
     7861 aaaaataaac aaagaagagt tgatccaatc agcaacaaat tccttaggta aacccgtacc
     7921 gttaaaggat gtatcggtta caatcaatga agtaccattg gaggatggtt atttgaccaa
     7981 acaaacaggt gattttacga ttatgtatag ttatcatgac ccgtattcac tccaagaact
     8041 ccatgctcag tcactattac atgttttacc attaaacaaa cagatagatc aaaaagaaca
     8101 aaaaagacaa gaagaaagct tgtcagaaaa aaaacaacaa atggctcatg cagtttctcc
     8161 aacagggaaa gtaaaacaaa caagaagcct agagttagca agaatatcta gaaaaatctc
     8221 agaatctaat aaaacgataa ggcaagaagc tcatttggcc ccacaagttt ctggattgga
     8281 aaatgaaatt ttagagccta aaataaaaca acaatcagaa aaagaatttg ttgctaaaca
     8341 gtcggaagat cagaaggaat cagatgacca gaaggaaacg aagaaaaaac gcttgtcaac
     8401 tattgattcc accgatgagc atctgcagcc gcaagtacca cttcctagtc cgggaacacc
     8461 cgcacctggt ggaggtattc cttcttctgc tttaggagat ttcatgcgag gtatggcagg
     8521 aacatgggta tacgctaatc gaaatgaatt tgacgcagat gactggttct gatttatatc
     8581 tctatctgtt atagtcaaat aagtagctga gtcatatgtt atttggcata atggagacga
     8641 ggagggatag aaaaatgtta gataaaacgt taccttacgc agaaatctgg atgacaagac
     8701 cacttcaaca aaatgttcca atcacgcctt tagcggaagg ttttgaattt cgattttatc
     8761 aaaaagaaga tgaatctgct tgggcggaga ttgagacttc cgttggggaa tttcaaacga
     8821 cagatgaagc acttgagtat tttcaacaaa actttgctcc ttatcctgaa gaacttgaaa
     8881 gaaggatgtt ttttgtagag acaaaaaaag gagaaaaagt agcaacctgt accgcttggc
     8941 gaaaaaaatc aagagagcaa gtgtatccgg tttttcattg gttagcagtg aaaccagatt
     9001 accaaggaaa agggctcgca aaagcattga ctgccagagt cttgcaagaa tttcctaccc
     9061 tccatacgga cggaccaatc tatcttcaca cacagacatg gagccatcag gcgattgctc
     9121 tttataaaaa aatgggtttt acttttattg ctgaaaatct agacggcaca cctaatccag
     9181 attatgaaaa agttatgcag gttttaagta aattagataa ataacgaaat ggtgaaataa
     9241 gtcctcagta ttgggataaa aaacgaaata gtcattcctc atatcttact tttttgagtt
     9301 aatactatcg gataactaat ggcatgccat acattcaaaa aagaaggggc agtgacaaaa
     9361 gtattgtcac tgccccttct cttgtttttt agcatgtttt atcgtttgat ttttttagga
     9421 ataaaattct tgatgaacgt aaatttttgg taatcgtttc gactatagag gtaaccaaat
     9481 acactgaaaa caactgctcc aataaaatta acaaataaat ccttcatagt atccatgatt
     9541 cccacgtcta agtaaccatt ttggatgatt gttttatctg ttttaccatc tgcattttga
     9601 ctttcaatga ttgtccgagt gatatctgga acatgataga cagtgtttcc gtctttactt
     9661 aactccacac tattgatttg ctggatgatc gtatcttttt gcatatcgaa ttgcagtaat
     9721 ttatctgctg aaaattccac aaactcccac ataacaccaa ctgtcatcga aaaacagaag
     9781 gaaacaactg ctagtaataa aggagtcaag ttcatggttt ttgtattttt attgagcaaa
     9841 taaacaaggg aaaagccgac acccccagct aaaaatccgc tgaatgcatg tagaaaagta
     9901 tcccacattg aaaaatagcc ataaaaatca cttaactctc ctaaaactgt tgaactaaaa
     9961 ataaaagata acaaaatgat ttctagcata tttggaatct gtatctttaa tatcttttcc
    10021 agaaaataag ggatttcaaa taaaattaat gtcagtaata aaagcattgt atttccccag
    10081 tgttggttcc agacctgatc cactagcata ataacgacga tgatacgtaa taaaatatag
    10141 attccgtttg tgattctacc tgcagttttt gtactgttcg taaaaaaggt tttcaaatga
    10201 ttcataaaat aactccttca tgtatatcct taattatact aagaagcgtg tgtttaccaa
    10261 agctatatga cttaaagaaa aacagagttg atattgtgaa aaaaatcact taatatagta
    10321 taaggagaaa agggggatac aaatgaaaaa attagttgct ggtttattaa cagccgttgc
    10381 acttcttgct atgagcgcat gcggcgcaga tcagaaaaat acagcgcaga caagttctag
    10441 tacgaaggaa tctgccgaag tatcatcagg cgcttctgaa caagtatata cagatccaaa
    10501 agaaatgaaa gaatcttatg atgtcgtgat tattggagct ggtggtgcag ggatggcagc
    10561 agctatcgaa gcaaaagatg ctgggttgaa tccagtaatt ttggaaaaga tgcctgttgc
    10621 cggaggaaac acatctaaat catcaagcgg tatgaatgct tcagaaacaa aatttcaaaa
    10681 agaagaagga atcaaagact cgaatgatgc cttctatgaa gaaacgctaa aaggtggtgg
    10741 aggaacgaat gataaagaaa tgcttcgata ctttgtcgat cactctgctg atgcggtcga
    10801 ttggctagat caaaacggta tcaaactgga caacttaacg atcactggag ggatgagtga
    10861 aaagaggaca catcgtccgt ctgatggctc ggctattggt ggatacttag tggaggggtt
    10921 attgaataac gtccatgagc gggaaatccc tatttttgtc aacgcagatg tgacagacat
    10981 taagaaaaat ggggaaacgg tcaatgaagt gactgtacat gttcaaggag aagaaccaaa
    11041 agaggtcacc ggaaaagcaa tcgtagttac cacaggcggt tttggtgcca gcaaagaatt
    11101 tattgaaaaa tatcgtcccg atttagctga ttatattacg acaaatcaag aaggatcaac
    11161 tggagatggt atcaccatga ttgaaaaatt aggtggacaa accgttgata tggataaaat
    11221 acaaattcat ccaactgtgc agcaggatga gggggtcttg attggtgagg ttgttcgcgg
    11281 agaaggagca atcttggtcg atcaagaggg gaaaagattt gtcaatgaaa tggatacaag
    11341 ggataaagta tctgcagcaa ttacagcatt gcctgaaaaa tcagcttatt tgatttttga
    11401 ccaaggcgtg cgtgatcgtg ccacagctat tgaattttat gaccaaaaag gatatgtcac
    11461 aactggaaag acaatggaag aattagcaga aaaaatcgat ttaccaaaag aaacactagc
    11521 aaaaacagtt gatggatgga atacggatgt tgcggagaaa aaagatgctc aattcaaccg
    11581 tgccacagcc atggaacatg acttatcgtc tccgaattat tatgcgatca aaatcgcacc
    11641 aggaatccat tacacgatgg gcggtgtgaa aatcaatacg aacactgaag tattagataa
    11701 agaaaaccag ccaattaggg ggttatatgc tgctggtgaa gtcacaggtg gcttacatgg
    11761 aaacaaccgg atcggtggaa attcagttgc ggagatcatt atttttgggc gacaagcggg
    11821 catacaagca gctcgatttg cttcggaaaa tgaatgaaat agaacgtaaa taaaaagagg
    11881 ttgtgaaatc agcgttttga gctaataccg agggtcagct gattgaacac tgtttagtga
    11941 agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt
    12001 cttatgtttt taacttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta
    12061 ttcggaaaaa gagcgtggga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt
    12121 ataaacggcg gaagcagaag aaattccttc ggaaataagc tgaaattcac aaaaatttga
    12181 aaagcaattt tcgtgaattt cttcttattt cttggagtta aacgcttctg tcccagcctc
    12241 ttttttgatc agcatgattt tattcagtta tcttcaaaat gatttttccg atgtttttgt
    12301 ttgcttccat atattcatgc gcttgtttga ctgcgctgaa ttggaatgta cggtcaatga
    12361 ttggccgaat cttgccattt tctagaaaag gcccagcttt ttgcataaaa gtttgtgcga
    12421 gctctgcttt atactgatca cttctaggtg tcaataatgt accaagcagt tggacacgtt
    12481 tcccaatcaa tacaccaagg tctatctcag gcacgatggt cccacctagc ataccaatca
    12541 agacccaacg tccatcaacg gctatagaag ctaaattctt ttcccagtaa gaagcgccga
    12601 tgaaatccaa aataacatcg actccccgac cttcagtgat ttttcgtacc tcttcttgaa
    12661 agtcttgttt tttatagttg atcaattcat ctgcaccaag ttctttacaa aaggcgagtt
    12721 tttcttctga tcctgcagta acgatgattt tcgcgtgaga aagctgtcta gctaattgga
    12781 tcgctgctgt tcccacacca cttgctcctg catggatcaa gacagtttcg ccttcttgta
    12841 attttccaag ccagtaaagt gtttgataag cagtcaaaaa aacttctgag attccagcag
    12901 cagaaacata gtctagcgta tcagggagaa ggattgcacg atcggcaggc atcacagcat
    12961 attcggcata accacctaga ttgactaatc cgtatacttt tgtcccagga gtaaaagtgg
    13021 agatatcact tttattctca actacctctc cagctacttc gactcccaaa atagggtagg
    13081 gaggtttcaa agagactgat tctcttttca taatatctgt tcgattgaca gctgctgtat
    13141 ggactttgat cagtaattcg ccttgttttg gtttaggaac aggcacttca atttgttcta
    13201 atacatctac agaaccagga tgcttgattg aaatggcacg catggatcta ttcctccttt
    13261 gcccattctt ggaatgctgt attcaactct ttgctacctt cagaaagtac tagagtcgta
    13321 cgagaaatat ccgtttcttc cactagagcg gcaagtacag cagcaactgt agagcgagtg
    13381 atcgtttttg atgccttctc attaggctta gttaattgaa tggaagtaac ttcttcatcg
    13441 ttagtcaatg tgactggttg aagaatgaca aaatctaagt tagttcgttt cagccattca
    13501 tctgcataat gtttagtaat ataataatct gtcatggact caggccattt tgctggttca
    13561 tctgcataaa cagcactgac catcagatag cgagagacat gcgcattttc agctgcgatc
    13621 actgttttga ttgcgccatc caagtctact tgcagaagat tctttccttg agagccggca
    13681 gcaaaaatca atacatcgat gcctttgaat gcttcggtca ttttttccac ggaccaagtt
    13741 aaatcaaaag agacatacga aacattctct ttttttacta atgtttggga agcaacatct
    13801 ctcacccctg caaaaatttc atgggaactt ggagctaaat cttttatcag gtgtcggcca
    13861 atttgtccgt ttgcacctac aacaaaaatt ttcatttgga tcatcctttc gacgtcaaat
    13921 ctttccattc aatagtaaca ccaaaagaga aaaaaatcag agatcggcta cgatgactat
    13981 cagttagtaa gagaagggtg cttgaagtat cttaacaaga cattgcatac tgctgcagtc
    14041 gcaagacctg cgacgattcc ttcaggtata ccacttgtaa aaataaccgc tagaatagct
    14101 gaataaacag catttaaatt tgttccgatg actttggcat aatcttgctg gaataaaaag
    14161 tagatcatat tcatcactaa aatcgtattg gtcaatgaac cggaaagtcc agctaagaat
    14221 aaagaaacgg aatctgcttt ttgtttcatt agtttgcgca gacctttata aacgaaataa
    14281 ggaaccaccc caatcaagat gcgaggaata aacgcgatca gcaaggcttt ccagcttcca
    14341 tgttctgttc cgatgactgg gataaacgga gaaaagacaa aagacaaagg tgtttggata
    14401 actgtgctac ggatcatgct gatcagtcca aatgtaccgc caagaaaagc acctagtctt
    14461 ggtcctaaaa cgatcgaagc aatgattaca ggaatatgca tggttgttgc attgattgga
    14521 ccgataggga taaaacctaa aggcgtaaca gctaataaaa tcaaaatagc taaaaacatc
    14581 gcagttaatg taaagttttt tgtatttttc ataagtactc cttttttcta agcatttctt
    14641 tcattaagag tcagcatgac ctgttcgatg atcgtctgaa tatcagctaa ggcacctttt
    14701 ccaaaatctc cacaagctaa aagagattct cttggttcaa tttcctgata gccgacagat
    14761 ctcaatgttt ccagattacg ctgagtgatc gggttttgat acatattcgt gttcatggca
    14821 ggggcaatca attttggtgt tcccactgga agcgccattg cgactgttga aagaagatcg
    14881 tctgcaatgc cgtttgctag cttgccgata atgtttgctg tagcaggcgc gatgagaaac
    14941 aagtcagctt gttttgctag ttcgatatga ttgattacct gcggatttga ttcttgcatg
    15001 acgtctgtat ggactgcgcg cttcgacaga gattgcaagg ttaatggcgt gataaaatgt
    15061 gtgctgcttt tagacataat cacatctacc tgggcaccta atttgacgaa ttgacttgta
    15121 agatcagcgc ttttgtaagc agaaatactt ccagtaacgc ctagtaagat ctttttcatt
    15181 ttgattcctc cagtctaatt ttctcagtaa tcaatgcagc aatctcagat ttactttgag
    15241 cttcttccac tgttccatct ttagataaga gatagccgtg gtgtgtctcg ccatggattt
    15301 ccgtcaaatc atttgcgaaa ataaaatcag ttttgttatt tatcagacta ttttttgcga
    15361 ctgccagaag agattccttt ggtacatcta ctaatagttt gaaaccaatg atttttgctt
    15421 ttggctgcca ttcacgtaga taagaaatga tttttggtgt tttcttcaaa acgagcacaa
    15481 gatgctcggt gttagaagag atctttgaaa cagtggtatc tgtctgttca ttttccgcaa
    15541 accaattgtc cagttcttct tgcgttgaag aagtgggtag gttttttgcc agctgttctt
    15601 ctgaaaaact aaaagcagga gtaaaatcac tgactgccat actgtggata atcgcatcgt
    15661 agtgttcttt tttcgttagt tcttctaatt gtaaaaataa gtccagtgca gattcgatcg
    15721 tataaatcgt tatattggag tgtcttttcg gtttcagtgc ttgtttcgta gtcacgtaat
    15781 cgattgtggt atccggattg gcagctaaat aatcagctaa tgcttgccct aatcgtcctg
    15841 tcgaatgatt tgtaatagca cgtacttgat cgattttttc agtcgttcct ccagctgtga
    15901 ttagaatctt catttatggt cacctacatt tactagtgtt cttccttggt gtgttccagc
    15961 aagtagttta gatgctgttt caggcaattg atccagagta atctcttgga cgaccagttc
    16021 atctgcaatc tgcaaatccg ccatctgttg ccataaagaa agacgttgat ctattggtac
    16081 attgacagaa tcaattccaa tcaactggat gtttcgcaga ataaaaggca agacagtcgc
    16141 gtttagtttg attcccccag cattgccaca taaagctact gcaccgttat aagagatcaa
    16201 tggaagaaga ctgcttagct gctcgccacc tactgtgtcg atgacatagt cgatttgctg
    16261 ttttcctaaa gcttttgttg tctctggcag aaattcatca ggtcgtacga cttgcaaagc
    16321 acctagactt tttagccatg tgacagactc ttcttttctg gaaaaggcaa tgattgactg
    16381 gaatcctagt ttatgtaaca gggctatcgc tgtactgcct acaccgccag aagcaccagt
    16441 aacgacaact tttttatcgg aggtcatacc ttgacggatt aaagcgttca cacacaacat
    16501 agcagtaaac cctgctgtac caaggatcat cgcttgacgc agcgtcatat tttttggtag
    16561 aggaactaac cagtctcctg gtactttttg atattggcta taaccgcctg gatgggtgac
    16621 gccaagccca aaaccagtag caagtacaag atcttctttt gaaaaacgtg gattgttact
    16681 ttggacgaca gttccggata aatcaatccc tggagtcatc ggatatgttc gtatcacctg
    16741 accagactcg ctcattgcca atgcatcttt ataattgaca tcagaatagg caatttttac
    16801 caagacttca ttttcagcca actcagtaaa tggcagatca ctgattgctg tatggaaaac
    16861 aggttccttt attacctgaa aagatcgaaa agcgttcatt cgtgagacac tccttttaaa
    16921 attttctttt atcataccat aaagcctact cttttattct tgttcttccg taaatttaga
    16981 caaaaattag gtgaaaaata aagaatcaaa caactagaat ttattccaaa agataaagaa
    17041 atattcagca aaaaaaattt tacaaagggt tgcctttttc aataaatttc gtatactaat
    17101 acgagtggta gtaaacagga agtttactat tagaaaactt cgattcggag gaaattatgg
    17161 aaattggtga gaagttaaga aatttgcgca tccaaaagaa tttgacacaa gaagaactag
    17221 gcgaacgcac agatttgtca aaagggtata tttcccagtt ggaacgagat ttaagttcac
    17281 catcaatgga aacattcttt tctattcttg aagtcttagg tgtgactcca gaagaatttt
    17341 ttcatcaaga agcagcgaat ctgcaagtgg tttattcaaa agaagatcat acggtttatt
    17401 tcgatgaaga aaacgggtat gaattggaat ggctcgtggc tgattcgaat gaaaaagaaa
    17461 tggagcctgt cttgctgact tttgaaggtg caggagaata taagacgttt gaaccttcat
    17521 tatctgaaac gtttattttt gtattagaag gggaattaga gttaagctta ggagagacgg
    17581 tctatgtggc aaaagcagga cagtcgatct attatcaagc gacaaaacaa catcaattaa
    17641 ggaatcatct caaaaaacga acaaaagtat tgattgttgc aacgcaatca tatttgtaat
    17701 atagggggta aaaacgtggg gaaaccaatc atttcatttg atcaagtagt gaaacgctat
    17761 gatgatgaaa cagtattaaa aaaagtaagt tttgagatcg aacaaggaaa attttataca
    17821 ctgcttggtc cttccggctg tggtaaaaca acgatcctac gtattatagc tggattcacc
    17881 gaagctacag aaggggacat ctattttgaa gggaaacggt tgaatgattt gccagctaat
    17941 aagcgacaag taaatacagt cttccaagat tatgcacttt ttcctcatat gaatgttttt
    18001 gataacgttg cttttggatt gaagatcaag aaaatgtcca aatcagatat cgaaaagaag
    18061 gtaaaagatg ctttgcgtat ggtccagctt cctggatacg aaaaacggga gattagtgaa
    18121 atgtctggtg gtcaaagaca gcgtgtagcg attgcacgag caattgtaaa tgaaccgaaa
    18181 gtattgctat tagatgaacc gttatcggcg cttgatttga aactacgtac agatatgcag
    18241 tatgaactgc gggatctgca acaacgatta ggaatcacgt ttatttttgt tactcatgac
    18301 caagaagaag cgttggcaat gagtgatgag atttttgtca tgaataaagg gaaaatcgtc
    18361 caaagtggta cacccgtaga tatttatgat gagccaatca atcatttcgt tgctgatttt
    18421 gttggggaga gcaatatcgt ggacggtgta atgatcgaag ataatctagt tgagtttgtt
    18481 ggtaagcaat ttgaatgtgt cgatggcggg atgcgtctaa atgaaccagt tgaagttgtt
    18541 ttacgcccag aggatttgac gatcacgaca ccagataaag gaaaactagt cgtaacggtc
    18601 gatactcagc tgtttcgtgg tgtccattat gaaatcatct gttatgatga acagcaaaat
    18661 gaatggatgg tccattcaac gaaaaaagct aaagaaggaa gcaaagtagg attggccttt
    18721 gagccagaag atatccatgt catgcgtttc aacgagtctg aagaagaatt cgatgcacgt
    18781 cttgacagct acgaagaata ggggggacaa gaatgaaaac aatgcgcagg atctattccg
    18841 tcccttatat tttgtggctc ggtttattcg tgatcgcgcc tgtattaatg atcatttatc
    18901 aatctttttt tgatatgaat gggcaattca cgctgaataa ttatctatct tattttacgt
    18961 cggggacatc gctttctatg acgatcaatt ctgtatggta tgcatttttg atcacgtttt
    19021 tcacgctgat catcagttac ccgactgctt attttttaac aaaactgaag cacaagcaat
    19081 tatggctgat gctgattatt ttgcctacat gggtgaatct gctgcttaaa gcttacgcat
    19141 ttattgggat tttcagtgtg cacggcagcg tgaatcattt ctttgatttt atcgggatcg
    19201 ggccgaaaca gatattattc acagacttca gttttctgtt cgtggcaacg tatatcgaga
    19261 ttccatttat gattatgcca attttcaatg cattggaaga gatgaatcct tctttgatca
    19321 gtgctagtag agatttaggc gcgaatagct ttgagacctt ccgacgagtg atttttccgt
    19381 tatcattaaa tggtgtgaaa agtggtgtcc aagcagtatt tattccttct ctttctttat
    19441 tcatgctgac tcgtctgatt ggcggaaatc gggtgatcac tttaggaacg gctatcgaac
    19501 agcatttctt ggttacacaa aactggggga tgggttctac aatcggtgtg attttaatca
    19561 ttgctatgtt catcgtgatg ctcctgacag gcgagaagaa aaaaggaggt cgctcataaa
    19621 tgaaaaaatt taaatggtcg tatctttatt tagggatcgt ctttttattc ttatatgcac
    19681 cgatcttcta tctgattttt tattccttca atgaaggagg aacgatgaac agctttacag
    19741 gatttacttg ggaaaattat gaagctgttt ttgaagatac acgtttgatc attatcgtat
    19801 tgaatacgtt catgctggct ttcttatctg cattgatcgc cacgatcatc gggacatttg
    19861 gggctatggg aatctattac acgaaaaaac gacgtgcacg gacagcgttg ttgagcatga
    19921 ataacatctt attagtctct cctgatgtta ttatcggtgc tagtttcttg attttcttta
    19981 cactactagg attcggatta ggttttcaga gtgtattgct ttcccatatt gctttcagca
    20041 ttccaatcgt cgtcttgatg gtcttgccaa aattgcagga aatgaacgat tcaatggtcg
    20101 atgcggctag agaccttggt gctaataatt tccaagtagt caaaaatatc attttgcctt
    20161 atctttctcc aggaatcata gctggatatt ttatggcatt tacctattct cttgatgatt
    20221 ttgcggttac atttttcgtc acaggaaatg gctttacgac gctctcagta gagatctatt
    20281 ctcgtgcaag acaaggaatc agtttagaaa tcaatgcgct aagtgcgtta gttttcttgt
    20341 tctccatgat attggtcatt ggatactact ttattagtaa agaaaaccgt ccaaaacggc
    20401 tgaagaaaaa cagaagagta cgcgaggggg tggcacggct gcgatgaaaa aattacaatc
    20461 tctgttttta ggtattctca tcattattgc ggtgctgctg cttggtgttc gtcaacttga
    20521 aaaaacaagt ggcatgagtg gagcaaaggt acttaccatc tataactggg gagattatat
    20581 cgatcctagt ttgatcacga aatttgaaaa agaatatgga tacaaagtga attatgaaac
    20641 atttgattct aatgaagcga tgttcacaaa aatccagcaa ggtgggacaa actacgacat
    20701 cgctatacca agtgaatata tgatccaaaa aatgatcaaa gaaaaactag tacttccatt
    20761 agatcattcg aagatcaaag gattaaataa tattgatcca cgatttttag acttggattt
    20821 tgatccagat aatcagtatt cgattccata tttttgggga actttaggga tcgtatataa
    20881 cgataaattc tttgatgcaa atcaaattaa gcattgggat gatttgtgga agccggaatt
    20941 aaaagacagt ttgatgctga ttgacggtgc acgagaagtt atggggcttt ctttgaatag
    21001 tttaggctat tctttgaata gtaagaatat ggcacagctg acagaagcag caaataaatt
    21061 gaatcattta acaccaaatg tcaaagcaat cgtggcagat gagatcaaaa tgtatatgat
    21121 caatgaagaa gcctccgtgg cagtgacatt ttctggcgaa gctgccgata tgatgtggga
    21181 aaatgaacat ttacattatg tgatcccacc agaaggatcc aatctttggt ttgataatat
    21241 cgttatgcca aaaaccgtga aaaataaaga aggtgcctat gatttcatca actttatgct
    21301 agaaccggaa aatgcggcac aaaatgcaga gtatattggt tattctacac caaatgaaga
    21361 agcaaaagcg ttattgccaa aagacatttc gtcggacgaa caattctatc catctgatga
    21421 cacgatctcc catcttgaag tctacaaaga tctaggatcg aaatacctag gcatctataa
    21481 tgacctattc ttagaattca agatgtatag gagataatgg caaaactcag taagaatggg
    21541 gacttatcaa cgttctaaag agctaaaaat cgtccttttt ctatctgagt tttccaatct
    21601 tctaccaaaa gcggatgaaa cgccgctttt tttgtgttat tttatttttt ctaccacgtt
    21661 tttctaccag agaaaagtgg acaaaaccat tgtaaaatag ggcccgagac gggctagtaa
    21721 atctaagatt gaaaaagtta cagaaggata aagtaattgg aaactatgca aatatactta
    21781 acccttctgt aatctattaa taaaactaat atatgaatcc agttcaatat ttgtagctat
    21841 gaaaaaacat aaaaatcata ttagataaaa actaaattgg tagataaatt attttgtcag
    21901 atatctgagg caaatattcg actatttgtg tttcaaagta aaaattggaa tacaaatata
    21961 gaatagacat attgcagccg atagtttatt atgcttttag acacattaaa ctggaggaaa
    22021 aaatgaaaaa gagcgctaaa gatcgagttt ttgatgagct gatacgacta acagggaata
    22081 tgtcttctgt cactgccgag aaaatttcga agaatctagg tatctctcgt cagaatgcca
    22141 gccattattt gacgagatta gtggaagata aaaaggtcga gaaattaccg ggaaagcctg
    22201 ttttgtggaa gcctttagat gaatatgcgg ttgtagataa tacggagcaa ataaacgaag
    22261 cctttcattc tgtagttggt catgacggaa gtctgagaga ggtcattcaa aaatgtatag
    22321 ccgctgtcaa atatccgcct aacggactca gtgtattaat aaatggagcc acgggtgttg
    22381 gaaaaagttt tttagccaca aaaatttttg aatacgctat ccatgagcaa attattgaaa
    22441 aagatgcacc atttgctatc ttaaactgtg ccgattatgc ggacaatccc gaactgcttt
    22501 cggcaacact gtttggatac aagaaggggg cctttacggg ggctgaaaag gataccgatg
    22561 gtttattggc aacggccaac aacggctatc tttttctcga tgaggtccat cgcctatcga
    22621 aagaaaatca agaaaagctc tttctattta ttgatactgg aaactatcgt ccagtcggtg
    22681 aaaatgtaaa ttggcattct gctaaggttc gttttatttt cgccacgacg gaaaaaggtg
    22741 aaaattattt attagacacc tttgatcggc gtattcaaat tagtgttatg ttgccaactt
    22801 ttgaagatcg ccccattcga gaacgattag agctgattca attatttttt caaaatgaag
    22861 cggatgtttt acaaaaagat attattgttt caagagaagc cttgtcttta atgttatctc
    22921 atccctttag tgggaatatt ggtaagctga agaatatcat taaaatcagt tgtgcggatg
    22981 tgtatagtcg aacacaagaa gaaccattaa cgattgggaa aaatgagatc ttgattcagt
    23041 taaatatgct ggaatccgaa gtagaaagct tgccgattgc tagtttattg ataaagaaaa
    23101 atcaaaagat aaaaacggat cgaatcaaac cgtttgatta tgattcgatt ttggaaaaaa
    23161 ttactcagct gataaatgaa ggtaatttca atgaaaattt ttcttcgata aagaatgaag
    23221 tacagcattt ggtgcatcac attgataagg attctttttt atcaatgagt agaaaattga
    23281 tgattcagat gtttagaaag gtctgggtat ccgttttagg aaaaacgtac ggattgacga
    23341 cgagtggacc tgttgcagaa attattagca gatcctatgt catttcccca agctataaga
    23401 cagacttaac cgggataaat cgtacattag ctgcaaatct acctcggacg acttacttat
    23461 gtaatcagtt cttggagcat ttaccaccgc tctcagaaaa ggacgagaac tttctaagac
    23521 tgcttattgt cgtgacttta tctgattatg tagatgaatc catcgagctg aagggcctgt
    23581 tgcttgctca cggagatagt acggctagca gcattcaagc agtagtgaat caattatgcg
    23641 gcaattatgt ttttgaagcg ttggatatgc cagtagagag taatgtgtca gagattgtcg
    23701 aatcgacaag gaatttcgtg aaacggcaag tgaatacaga tagtctagtg ctgatcgtag
    23761 atatgggctc tttaaatcaa atttacacac agatcaagaa cgatttaaaa ggggagttac
    23821 ttcttctgaa taatttgacg acttccattg cacttgatat tggcttgaag atgacgatga
    23881 atgcgccatt taaacagatt gcggaggatg cagcagacaa gtattcaatc aatgttcaat
    23941 actttgaagg cttttctcaa agtagcaaca ttatcatttc ctgtatgtcg ggtttgggga
    24001 tttcggacaa attgaaagat gtttttcgtc atcatttatc ggatgaatcc atcgaagttt
    24061 tcacgaagga ctacagagaa ctacgtgaat taatcgacca aaatgatgaa acttattttg
    24121 acaagacaaa attggtcatc acgacttcgg atcttccacg ttccttttca attcctaata
    24181 ttaatgttta tgacatctta gacggtgatg gagcagccaa tttggagcat attttgagtc
    24241 ctgaaatgaa gccggcagaa tttaaccgct tgattcagga gctagtaaaa ttcttttcgt
    24301 tggaaggaat tgcggaccgt ttgaactttc tgaacccaac gatcgtgatg agtgaagtgg
    24361 aaacagtcat ttctaaatat gaaaattact atcatttcac tttaaatggc cgtgtaaaac
    24421 taaatctcta tatgcatacg gcattgatga tggaacgttt attcttggct cggacagaaa
    24481 aatctgaaga accgaattat gatttgaaac cagatgaaga tgaattttat tatgtttcta
    24541 gaagtatttt tcaatcaatg gagatgaaat ataattttaa agtcaatgct tatgagcttt
    24601 cgctgctcta tgaattatta ggaccgtata ttcaaaaata aagtgtctaa aaaagtgtct
    24661 aatctgtttt ttttaggtta gacacttttt ttaatgtgaa ttaacgtgat taaaccaatg
    24721 tttttaaaag ttggcacagg aattgcttat ataaaagtga acagaaagaa aggaattaac
    24781 catatgaaga aaattctaat agcgactcac ggtcacttag cttcaggctt tcttagcagt
    24841 attcaattac tgacggggaa ggttcaagag attacggtga ttaatgctta tgtggatgag
    24901 tgtgattttg aacaggagtt gaatgtattt gtaaaccagg tgaacgagca ggatcagatt
    24961 tttgttttta ccgatttatt tggcggaagt gtcaatcaga agattaccaa aacctttttg
    25021 gagaaagaga ttgctgtaac tattttgtct ggctttaatc tgccaattct gctcgaaata
    25081 gtattggcaa ccaaggaatt aacaaaggag gatattcagg aactggtaaa taaatgccaa
    25141 caggaattaa agatgaccat tcttgatgag gtacatgtag taaatgaaga ggaagatttt
    25201 ttttaggagg aagaaaaatg attaaagcag tgcgaattga tgaacgatta attcatggac
    25261 aagtagcgat gacttggaca aagagtctaa atttaaccgg gttagtagta gcaagcgatg
    25321 aggcggctac caacgatatt caaaagatga cattgaagat ggctgcacca tcgaatgtca
    25381 aagtcattat taaaacagtt gatgacgcga ttcatttgtt aaaagatccg cgggcgaagg
    25441 acatgcgctt gatggtttta gtccctaatg tcaaagatgc ggtaaaagtt gcgaaagctt
    25501 tcccaacgga aatcgaatta atgaacgtgg ggaatgctgg gaaaatgaca ccgccatcgg
    25561 aagataagaa aaccttatca aaggaagtga tgttaacgac gtcagaaatt caagacttaa
    25621 aagaattagt tgaactttat ccagataccg tttttcagcc tacaccggcg atggaaaaac
    25681 gttcagctat ctctattttg agtgattttt agaaaaagga aggagaaaaa ttatgtatga
    25741 tgcatttgta gtcgctttgg ccgtttttat tggagttgct ggacatgaaa tgttcgggat
    25801 gtccatgctg agtcgtccga ttgttgttgc tccgttagca ggagcgttga tgggggattt
    25861 gcagacgggg ttgattgtcg gggcgtcact agaagccatc tttatgggtg tcgtcaatat
    25921 cggaatctct agtacggcgg agccttcttt ggctgctggg ctggctacag cgttcgcaat
    25981 caaaatggga ggaaacgtgg atgcgattat tcccattgtc tttccactag cagtattagg
    26041 attacagtta atgaatatga ttttttcttt tgtatgtgga ccgatggctg ctaaattttt
    26101 caaatttgca aaatctggtg atcaaaaagg aatcatcaat ctgcacttct ttatgtggtt
    26161 tgtccactat gcgctttatg ctcttattcc attctttgcc gttttatttg gagcagatgt
    26221 tgtcaaaagc gtcttggata atattccaga ggtcatcatg aacggattaa cagtcgctgg
    26281 aaatctgctg ccggcagttg ggatggcgat gctgttacgg atgctttgga gtaaaaatat
    26341 tgctgtgtgg tttttctttg gggccgttgt tatggcgtat ctcgagttac cattgattgc
    26401 aattgccgca gttggaacga ttattgcaat tgttatagcc caaagagatc tacaactaaa
    26461 aaatatatct gttcatgcag ttcaaagcga tgctgctgta aatgcaacgc ttgaccaaga
    26521 agaggaggat ttctttcaat gaaattagct gatggaattt ctaaagatga gaaaaaattg
    26581 gttcggaaga tgttttggcg ctcgatgact atgtatgctt cggtgaatcc ggtgacgatg
    26641 ggcggcggtg gtttcgccta ttctatgatg cccttcatta atcatttcta caaaagtgaa
    26701 gaagatcgag ctgcggcgct ggaacgtcat acacagtatt tttcgacgac cattccttgc
    26761 gcgtcctttg tcatggggat tgcggcatcg atggagaagg aaaattctga aaaagctggt
    26821 tttgacgtgg aaagtatcaa cgcgatcaaa acgagtttga tgggaccatt ggctggaatt
    26881 ggcgattcat tgttctgggg agtttggcgt gtcgttaccg cgggactagc gatcaactta
    26941 gccaatgccg gaaatatttt ggcaccaatt atctttttag ttatgttcaa tatacctaat
    27001 tacttgatgc gatactatgg cggcgtttta ggctattcat taggctctaa atatattgaa
    27061 aagctgtatg cgaacgggtt aattgaaatt ctgacaaaag ctgctagtat cttgggtctg
    27121 atcatggtag gtgcaatgac gatcagtatg gtcaaattca ataccgtttt gagcttttca
    27181 atgaagggcg aagaactaat gaatgtccaa gaaatcctcg atagtatttt taaaggaatt
    27241 gtaccgttat tggtaacatt gagctgtttc aaattactag ataaaaaagt cggcgtcatc
    27301 aaaattattt ttggaatggt cgtcttggga attttattgt cattacttgg aatcgcatag
    27361 taggaagctg cagctactag gctgcagttt ttttagcaag gagggaaaag atgactatta
    27421 atgaagtaat ttattcaccc aaacacccat tttttaatgc tgagttaaac gacggaaatg
    27481 tgactacttc aaacgaatac agctactatc ggaatattcc tgatgtaaag ggattgacct
    27541 tcgatgtaag taatcaaaag acattagcaa accttgatgt ttgcgggacg attcaaacgt
    27601 tgacctttta tcgagaaaat ttactaactg aggaaaaacc aggtgtttgg gtcaataaac
    27661 agctctctca aaccaattcg ttatccttaa aggttgaagt aaacgggatt gtctaccatt
    27721 tgtcagaatc ggatcatcgt attgaagtcg atgtgattca agactgtttg cctagatata
    27781 ttcatcatta ttcgacgttt aaggtcattg tagtatcctt tgctcccata ctggctaata
    27841 agcgtttaag tatgcttgtt caacaggttt acattgtgaa tgaaacacac gaaagccttc
    27901 aagtttcagt gaaagatgtg ccttcgtatc aagagaagta ttcggatcag caaaatgtgt
    27961 tgatttctca aaaaggaaat aaggacacga tcgcacaaca ggaagtggca agcttcgcca
    28021 ttgcttttgt ggacccaaat gcttttgaag aagtaatgac ttttcaggaa tctgatatcg
    28081 aaaaatggct gaaggaaaca ttgaactatt ttgctcagct atttgggcag ctgtcaatgc
    28141 caaacgatag agttgtccat ctctatcgtc gtgcacttta tcaaagcttt tctagtttcg
    28201 gtatgaatcg acagggacag gtcgtcggca gcaattgggg cagctatcct gctactaatc
    28261 gaatttggaa taaggatatg tattacgcat cattgccatt caccatgttt gaaccggagt
    28321 tatgtcaaaa aacggttcta tggtttgatc aatatggcgt taagtttcct ggttcaaaat
    28381 ttacaggagg tatcaatcat tctctgagta attcgttatc cagtgcgtta ctggctagtc
    28441 tttattttga acatactggg gatacaaaat tctttgagcg gtgtccgcag gttctactga
    28501 atgcttcaag aattattgag gacatattag ctcaacgtcg gtcaggggaa ccaatgcttt
    28561 ttccatctgt ttggttatca gacgcctttg cacttggaaa gtatcatacc ggcagcaatc
    28621 tttgtctttg gaaggcctgt attggacttg cagaaatttt tgaagcccta gaacaactga
    28681 gtcttagcaa gcgatacaaa aacattgcct gtaaactaaa ggaatcaatt tgtaaacaaa
    28741 tgactatcga tggtcctttt ggtgagcaat ttttggaggg aatcggtgat gaggagaaaa
    28801 caacctattc agtgaagcac tatcaaaaac cgattcttga gcaagggtta atctttttaa
    28861 gtgatgtgat tgtggatgga aaaattaatt tattgatgca tgatggagaa gaatcagaca
    28921 ctacgttgat gcctttttat caatttttag ataataaaga tcatttatat cagaacacca
    28981 tggccttttc tgctagttct ttcaatccaa cctatagcga ggaaatcaaa ggcatcactt
    29041 ggggattaga atccggcgcc acttttcctg gctttatcac tgttttaatg agcgagctgc
    29101 acaaccctca agctttcgta acccgattag aagaactaat ttgtttggca gatttagacg
    29161 gttcgtggtg gtggtggccg tatcgcttag aggctcaaca aggagaagtc gtgcgagact
    29221 ttggctgcgg caaatgcggc tgggcatcgg gtctttttgt cagcctaatg atcagtcaat
    29281 atttcggatt gaaattcaaa aaaggagtat tgcaaattga tcctgttgat aatttaacgt
    29341 tttcttggaa gaatttgaag ttcggtcaag ccttcatttc gattgaatgt acgcaatccg
    29401 agttgagtat ttcaaatttg tcagaaaagc cattgaaaat aagtgatacg aaaaaaattc
    29461 ttcacgtaga aaagggaaaa acgattcaca ttcaaaggag aaaaagatga gtatactaaa
    29521 aaatattacc caatttaaaa aaatccagag tcgagcaatc actcccgaaa atccaacagg
    29581 cgagaaaggt aaagctgcga tgttgccaag cgagctagga ccaagccgca aaggtcgtgg
    29641 cgcaattccg ctgacttctg gtgaagaaac tgtgattgcg gatattactg gaacgggaat
    29701 aattcgtcat atgtggatga cgattcgtga tcgaacagaa tttggcagtt ttgttttacg
    29761 tgatttaatc ttaagaattt attgggatgg gtcggatagc cctgctgttg aaagtccttt
    29821 aggggatttc ttttgtaatg ggtttggaga gcgttgcgag gtgaactcgt tgccgatagt
    29881 ggttaatcct acagggggct ttaattccta tttcgaaatg cctttccaaa catccgctaa
    29941 aattacgatc gagaatttac atccgaagga tatgtcctca tttttttata cgataaatta
    30001 cgctttggtg gacgaattgg aagaaaatag cctatatttt cacgcaaatt ggcatcggga
    30061 acgcattacc aaattacagg aggattataa gttaattgat cgattaaagg gtcaaggcta
    30121 ttacgtgggt acttaccttg cgcttacctg cctagaacgt tattggtggg gcgaaggcga
    30181 gtttaaattc tacattgatg gggatagtga gtatccgacc gtaacctcaa caggttcaga
    30241 agattatttt ggcggggcgt gggcctttca tgagtacgat gagttcggac gtccacatgc
    30301 gaaaaactat tcaacagcct ttttagggta tccttaccaa tcaaatagag atgccacaag
    30361 agatcgtttt gaaacgggaa aattgaatgc cgttcatgcc tttggtgacg acgcaatgcc
    30421 acgacatggt ctttatcgtt ggcatcttca agaccccatc tgttttaccg aagatttatc
    30481 ggtcacttta caacaaatcg gcaacgatga tgttcgctta tttgagcggc aagacgatgt
    30541 tgctagtgtc gcttactggt attcaacaga agcttcagga aatactaaac gtcatttcac
    30601 tgatcgagaa cgcttgccgc gttaatgaag tgtttttcac atattcgaag ggaggaacct
    30661 atgatgatat atggggcaat tgaagctgga gggactaaat ttgtctgtgc agtcggtact
    30721 gaggaattaa cgattttgga aagagtcagt tttcccacaa caactccagt tgaaacaatg
    30781 aagcaggtca ttgatttttt taaacctttt aaggaacaat tggcaggcat cggggtcggc
    30841 tgctttggtc caattgatat tcaatgcaaa tcaacgagtt tcggtcatat cacatcaaca
    30901 ccaaaacttg cttggcaaaa tttcaatttt gtaggaacgc taaagcaata tttcaatatt
    30961 ccgattgaat ggacaacaga tgtcaatgcg gcttgctatg gtgaatatgt tgctggttct
    31021 ggcaaagggt tagcaggtgt tgcatacttc actgtgggaa caggtatcgg aggtggtgcc
    31081 ttgttcaatg ggactttcgt ggaagggttc agtcatccgg aaatggggca tatgttgatc
    31141 aagcgacatc caaaggacaa tttttcagga aactgtccct tccaccaaga ttgtttagag
    31201 gggatggcag caggaccagc gattgaaaaa cggttgggtg taaaaggcca gaatttattg
    31261 gctgacgatt cgttttggca gattgaagcc ttttaccttg cccaatgtgc atacaataca
    31321 acactgatgt tttcgccaga tagaattatt tttggcggtg gtgtaatgaa acaagaacac
    31381 atgaagaaaa aagttcagga taaatttgtt gagcttataa atggatatgt tgaaatacca
    31441 ccaattgata gctacattat tacgcccgaa ttaggtgata atgccggaat aatcggcgga
    31501 ttagcattgg ccagaaaagc ggtaagaaat aagcaaccat aattaatgaa tgtttcattg
    31561 atactcatgt caaaagtatt taaccgagta atcaaatgat caaatgaagt tggataaagc
    31621 gaaaatgaat tcaaataaaa aggctctaag tcaaatcgtg ttgttttcat taaatcactg
    31681 aaaggaaatg cttctgcgtt tccttttttc tttttgttgt gcgctgtata ccttgaggat
    31741 attcactggt ggcgtacact taaatagtaa tatattgtgt tactttatgt ctgtggtaat
    31801 agttatagtt gcttaccaat gtatgttcat ttttcgaaat gttgacttca taatccttgg
    31861 cttaatgttt gaattttttt ggtgatagat tttttcagcc gtataaaata
//
LOCUS       DAZKNV010000031        31089 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000031 DAZKNV010000000
VERSION     DAZKNV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.031"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            117..494
                     /locus_tag="ACG8M1_001572"
     CDS             117..494
                     /locus_tag="ACG8M1_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422291.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            complement(674..1969)
                     /gene="purB"
                     /locus_tag="ACG8M1_001573"
     CDS             complement(674..1969)
                     /gene="purB"
                     /locus_tag="ACG8M1_001573"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFQ0422292.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1982..3106)
                     /gene="purK"
                     /locus_tag="ACG8M1_001574"
     CDS             complement(1982..3106)
                     /gene="purK"
                     /locus_tag="ACG8M1_001574"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFQ0422293.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(3099..3587)
                     /gene="purE"
                     /locus_tag="ACG8M1_001575"
     CDS             complement(3099..3587)
                     /gene="purE"
                     /locus_tag="ACG8M1_001575"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFQ0422294.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(4003..5310)
                     /locus_tag="ACG8M1_001576"
     CDS             complement(4003..5310)
                     /locus_tag="ACG8M1_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFQ0422295.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(5313..5894)
                     /locus_tag="ACG8M1_001577"
     CDS             complement(5313..5894)
                     /locus_tag="ACG8M1_001577"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFQ0422296.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(6010..6107)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(6466..7758)
                     /locus_tag="ACG8M1_001578"
     CDS             complement(6466..7758)
                     /locus_tag="ACG8M1_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0422297.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7755..8378)
                     /locus_tag="ACG8M1_001579"
     CDS             complement(7755..8378)
                     /locus_tag="ACG8M1_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422298.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(8381..9217)
                     /locus_tag="ACG8M1_001580"
     CDS             complement(8381..9217)
                     /locus_tag="ACG8M1_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422299.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(9234..10121)
                     /locus_tag="ACG8M1_001581"
     CDS             complement(9234..10121)
                     /locus_tag="ACG8M1_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422300.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(10137..11420)
                     /locus_tag="ACG8M1_001582"
     CDS             complement(10137..11420)
                     /locus_tag="ACG8M1_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422301.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(12103..12786)
                     /locus_tag="ACG8M1_001583"
     CDS             complement(12103..12786)
                     /locus_tag="ACG8M1_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFQ0422302.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12804..13421)
                     /locus_tag="ACG8M1_001584"
     CDS             complement(12804..13421)
                     /locus_tag="ACG8M1_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0422303.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(13431..14255)
                     /locus_tag="ACG8M1_001585"
     CDS             complement(13431..14255)
                     /locus_tag="ACG8M1_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFQ0422304.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(14248..14808)
                     /locus_tag="ACG8M1_001586"
     CDS             complement(14248..14808)
                     /locus_tag="ACG8M1_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422305.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14982..15938
                     /locus_tag="ACG8M1_001587"
     CDS             14982..15938
                     /locus_tag="ACG8M1_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0422306.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(16243..17199)
                     /locus_tag="ACG8M1_001588"
     CDS             complement(16243..17199)
                     /locus_tag="ACG8M1_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFQ0422307.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            17303..17905
                     /locus_tag="ACG8M1_001589"
     CDS             17303..17905
                     /locus_tag="ACG8M1_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0422308.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17993..19492)
                     /locus_tag="ACG8M1_001590"
     CDS             complement(17993..19492)
                     /locus_tag="ACG8M1_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFQ0422309.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(19508..20032)
                     /locus_tag="ACG8M1_001591"
     CDS             complement(19508..20032)
                     /locus_tag="ACG8M1_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFQ0422310.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            20330..21079
                     /locus_tag="ACG8M1_001592"
     CDS             20330..21079
                     /locus_tag="ACG8M1_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0422311.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            21070..21855
                     /locus_tag="ACG8M1_001593"
     CDS             21070..21855
                     /locus_tag="ACG8M1_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0422312.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21824..22540
                     /locus_tag="ACG8M1_001594"
     CDS             21824..22540
                     /locus_tag="ACG8M1_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0422313.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22642..23661)
                     /locus_tag="ACG8M1_001595"
     CDS             complement(22642..23661)
                     /locus_tag="ACG8M1_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFQ0422314.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23680..24681)
                     /locus_tag="ACG8M1_001596"
     CDS             complement(23680..24681)
                     /locus_tag="ACG8M1_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFQ0422315.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            complement(24959..26107)
                     /gene="nagA"
                     /locus_tag="ACG8M1_001597"
     CDS             complement(24959..26107)
                     /gene="nagA"
                     /locus_tag="ACG8M1_001597"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFQ0422316.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(26183..27019)
                     /locus_tag="ACG8M1_001598"
     CDS             complement(26183..27019)
                     /locus_tag="ACG8M1_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422317.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(27203..28420)
                     /locus_tag="ACG8M1_001599"
     CDS             complement(27203..28420)
                     /locus_tag="ACG8M1_001599"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0422318.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(28569..28730)
                     /locus_tag="ACG8M1_001600"
     CDS             complement(28569..28730)
                     /locus_tag="ACG8M1_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422319.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            28803..28886
                     /locus_tag="ACG8M1_001601"
     tRNA            28803..28886
                     /locus_tag="ACG8M1_001601"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28837..28839,aa:Leu,seq:gag)
     gene            complement(29126..29716)
                     /locus_tag="ACG8M1_001602"
                     /pseudo
     CDS             complement(29126..29716)
                     /locus_tag="ACG8M1_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            29839..>31089
                     /locus_tag="ACG8M1_001603"
     CDS             29839..>31089
                     /locus_tag="ACG8M1_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0422320.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT         9310 a         6607 c         5370 g         9802 t
ORIGIN      
        1 tgttttatca gaaacgaaaa tcttatacca tcaacaagcg tttacattta tacttaatga
       61 tggtatatta gaattaacta aaaatttgga taatgggttc gaggaggcac ttgccgatgg
      121 aagatgcaat aaaacaaggt cagctttttt tatcagaatt aacagctgaa gaacgttcct
      181 gtctatataa tgatttgctg tcgatcaaag acgtttattt atgcaataaa gatactagtt
      241 tttatacatt ccgaaaaatc cgccgagcaa ccaagcgctg tgctgaatgc cgtaaaagga
      301 cttttcttta tcagacagaa cacaaaggcg aactttcaat cagtcagatt catgaacaga
      361 agcgtttcaa aaatcattat cgtatccaga tcttattcaa tggacaagag atggaatacg
      421 cttttctcga aaacttgctg caacatctcc ataaccagca ttttagttat aatagccaag
      481 ccatttacgc ttaattcctc tattttttgt atgtaaagag gcacggtaaa gaggtagccg
      541 cttttaaaat caggttccta ttattgataa gaaaatataa taaactaaaa gaagcagaac
      601 cgctaacgga tctgcttctt ttttggttat ttttgctatt ctattttaat tgaattttgc
      661 aactcactct tctttattcc aaacctactc gtttgaatat cacgtcaacg tttttcaaat
      721 gatgatgata atcaaaggca tcgtctattt cttctttaga taataccgat gtgatggttg
      781 gatcttcttc taacagcggg cggaactgca cttggttgtc ccaagcgtac gcagtttttg
      841 gctgaacaag atcataagct tcttctcttg tcattccctt atcgatcaat ttcagcataa
      901 cgcgctggct ataaatcaaa ccaaatgttg cagacatatt ccgcttcatg ttttcaggaa
      961 agaccgttag atttttaacg atattgccaa aacgatttaa catgtaattc aataaaatcg
     1021 tggtatcagg caagatgatt cgttctgctg aagaatgaga aatatctctt tcatgccata
     1081 atgtgacatt ttcataggca gtgaccatgt gtccgcgcac cactctggct agaccagcca
     1141 tattttctga accgatcgga ttccttttgt gcggcatagc agaagaacct ttttgacctt
     1201 tcgcaaaaaa ttcttctact tcacgtgttt cggatttttg caatccgcgt atctctgttg
     1261 caaaacgttc aatacttgta gcaataagcg ccatcgctga gaaatattca gcatgtagat
     1321 cccgagggag aacttgagta gaaatttctt gtggacggat ccccaattgt ttacatacat
     1381 actcttcaat aaatggcggg atatttgcga acgttcccac tgctcctgag atttttcctg
     1441 cttctactcc ttttgccgca tgttcaaatc gttcgatgtt ccgtttcatt tctgaatacc
     1501 atgtggcaag tttcaatcca aaagtagttg gttcagcatg gacaccgtgt gtccgaccca
     1561 tcatcactgt atatttgtgt tcttttgctt tttcgccaat gatttccgta aaacgtttca
     1621 agtcttcccg taaaatatca tttgcttgct tgatgagata gccataagca gtatctacga
     1681 catccgtact tgttagacca taatggaccc attttctttc ttctcccaat gtttcagaaa
     1741 ccgctcgtgt aaacgcaacg acatcatggc gtgttaattt ttcgatttcc aagatccgat
     1801 cgatatcaaa tgatgcatgc tcacgaattt ttttcacatc ttcttgcggg atttcaccaa
     1861 gttctgccca agcttcatct gctaaaatct cgacttcgag ccacgcacgg tatttgttct
     1921 cttccgtcca gatattcccc atttcagggc gtgtataacg ttctaacatg ttttttctcc
     1981 tctaatccca aatattcgtt tgtttgattt cttccagcgt ttgctggatg tcttctgtca
     2041 agatagtgat atgtcccatc ttgcgacctt tttttgcttg tttttttcca tagaaatgga
     2101 attgccagtc tggcttattc tcaatcaagc gatagctttc cagcagttgt tctcccaaaa
     2161 cattgaccat tactgcattg cttatcaaac gtactttttc tcctaatggc caaccacaaa
     2221 tacctcgaat atgggcatcg aactgactca tagaacaagc ttcaatagaa taatgtccag
     2281 aattgtgagg acgaggagct aattcattca catatagccc gcctgttttt gttaaaaaca
     2341 tttctacccc taaaacacct gaaaggctca ctgcttctgc aatcacacgg gcaatacgct
     2401 cagcctcctc gatcacatcc tgatcaatcg cggctggagc aatcgtttca tgaagaatat
     2461 tgttgtggtg gatgttttcc acgaccggaa aagtcgtgaa atctccttga ccatttcctg
     2521 ccaccatgat cgaaatctct ttttcaaacg ggatccatgc ttctaaaaca caggttcctt
     2581 ctcttaaaag gtccatggca ggagctagat ccgcccgact tttcaaaaca tactgcccct
     2641 tgccatcata gccgcctcga gtggttttca aaacacaagg atagccgatc ccgtcaatcg
     2701 catcttggat atccgtcgga ctgacgatcg ttgcataagg agcaatcacg atgttattcg
     2761 tttccaaaaa agatttttct aacaggcggt cttgcgtaat cgcaagcaag tctgtccctt
     2821 gaggaataaa tgacatgggt aaaatcgcat ttaacgcctc tacactgacg ttttcgaatt
     2881 cataggtaat gacatctgtt cttctggcaa gctctttcag cgcaaaggtg tcatcataga
     2941 cactttcaat atgccaatct gcaacttgtg cggctggaca atcgctcaca ggatccagca
     3001 cacctacttt aaagcccatt tcttttgcac taatcgccat catacgacct aattgaccgc
     3061 caccgacgat cccgatcgtt gaaccaggca acaaaggttt aaccaagttg atcactactt
     3121 tctataacag ttttagccaa cattgaacgt ctttcagcca atttagcctc caattctaaa
     3181 tcatacatgg aaagcatctg tatcgcaagt agtccagcat taattgctcc cgcttttccg
     3241 attgctgtag tagctacagg tactcctcca ggcatttgga caatcgaaag aagcgaatcc
     3301 aaaccattta atgttcgtga ttggaccggt acaccgataa ccggcaaagt tgtttttgat
     3361 gcgaccatac ccggcagatg cgcggctccc cctgctcctg caataatgat tttgattcct
     3421 ttttttcgag cgttttgtgc atattcaaac atcaaatctg gggttcgatg agcagaaacg
     3481 accttttttt cataagacac accgaattca tccaatattt gacatgcttc tttcattgtt
     3541 tcccaatctg aagtactccc cataatcaca gagatttttg ctgtcattgt ttttcctccc
     3601 agtttttcta cattcatatt ttaacaatca ctttttttga tgtcaaagaa atttcgaatg
     3661 ttaacaaaga aaaacatttt attgttcgtg tttattaaag ataaaaaaaa ggaatgtgac
     3721 aaaagttagg tcacattcct ttttatggat aaacggtgtt ctcctgccaa ctcctcggtc
     3781 acaaggaaca atattcaaca aacatgagaa gctttttttt gaaattgttc cttgtgactc
     3841 ggagatgaac ggcaggctca cgacctcttc cttcaacggt gttcaatcag ctgaccctcg
     3901 gtattagctc aaacaaacgg caaaatacga ggaactattt ttccgtttgt ttctctaaca
     3961 atcaggtcaa aacgctgatt tcacaacctt tcttttgctc tattacttct tgaaggcttc
     4021 ttccaatatt tcttcatctt ttttcaatcc attaaagatc aaattcaata tgatagccgt
     4081 aatgctactc attacgatgc catttccagt gaacatttgc aatgtttgcg gcatttgact
     4141 gaataatgtc ggcgtaacat tgaaacccag cccaaatcca acagaaacag caacaatcaa
     4201 tagattttta tcattgctga aatcaacttc caacagcata cggattcctt ggactgccac
     4261 catcccgaac atgactaaca ttcctccacc aagtaccggc tcagggatga tttgtgctaa
     4321 cgcaccgatt ttagggaata atcctaaaac aatcaagaag aatgcagaga aatagatggg
     4381 ttttcttgtt ttgattcccg aaagttgaac caatccgaca ttttgagaaa agccagtata
     4441 agggaatgta ttgaaaatac cgcctaagat aacggcaagt ccttctgcac gatatccctt
     4501 tttcaattct tcttctccaa catttttccc agtaatgtca ccaagtgcaa aatatacacc
     4561 tgttgattct accatgctga ccatggaaat gatgatcatt agtaaaatcg accatacgtc
     4621 gaaagttggt ttaccaaaat aaaagggttg tggaacatgg aacaacggcg catctccaat
     4681 cgcgctcaga tcaatcattc ccatgaaagc agctaagatg cttcctccga ctaaaccaat
     4741 caataccgcg attgaacgaa tgaacccttt tgccagcatt tgcacgccta caattaggag
     4801 aatcgtcaca aatgcaagta gcagatttgt tttgtcacca aaatcagctg ctgttgcatt
     4861 acctccaccc attttctcga ttgctacagg aatcaaagtc aaaccaataa cggtgataac
     4921 cgttcctgtt actataggag ggaatagttt tttaatttta gaaaagacac cagaaactaa
     4981 cacaacaaag atcccagaag cgataataga tccgtagata gctcctactc cttcattggt
     5041 tccgatcaag atcagtggag ctactgcttg gatcgcacat cctaaaacga caggcaagcc
     5101 aattccgaaa aatcggttaa ctgtcaattg caataatgtc gctaatccac acataaagat
     5161 atcaattgaa atcaaataag tcatctgttc ttgattaaag cctagtcctg taccgatcaa
     5221 aagaggcacc gctactgctc ctgcatacat cgctagcaga tgctgcagcc ctaaaaccgc
     5281 agcttttcca ttttgtgttt ctttttccac gattatgcgt cctcctcaag aaactcaact
     5341 tgtccattcg tcaaggaagc aatacgcgca agagaaacga ctctcaatcc catttcttca
     5401 agtaactgac gtccatcttg gaaagacttt tcgatgacga tcccgattcc ttctacttgc
     5461 gctccagctt gctggcataa ttcgatcaat ccttttgccg cttgtccgtt tgccaagaaa
     5521 tcgtcgataa tcaatacttt gtcttctgaa gataaaaatt tacgagaaat agaaatcgta
     5581 cttgtcactt gtttcgtaaa agaataaaca gaagctgtca ataattcttc atccatcgtc
     5641 aaactttttg cttttctagc gaagatcatt ggaacatcta attctcttgc agcaaataaa
     5701 gctggtgcga tcccagaagc ttcaatggtc acaactttcg tgattccttg ttctttaaat
     5761 acttctgcaa accgttttcc catttgttcc atcaatacag ggtctacttg gtgagtgacg
     5821 aagctgtcga cttttaatac gccctcgcct aatatacgtc cgtctttttg aatacgttca
     5881 actaattctt tcactttatt tgctccttta tcatttatta ataccgaaat aaccgctttt
     5941 gtgcaaaaac ctactatgtt tctgttaaag aaaaacaccc tccactttat cataagaaaa
     6001 gaagggtgaa atagccaatc ttttacttat agtccagcat ttacggtact ggctagaaac
     6061 tgtcatccat attatgacga tatataagta ggtatgtaaa actaataata gtgtaaattc
     6121 attttcttgc aactgttttg cacgtgaagg cagtttgcca tatttgaata aaaaatgttg
     6181 tttcaaatat tgaaaacagt ctaacactac tttctgaaac tgacaacgtg gtttacttat
     6241 ttttttgtaa aatctaatga tttttaatgc attattcctt tttgttcggg tttaaatagt
     6301 tatttttatt ttctcctatc taaaaaagca gcccacataa aaagaaggca tgacaaaaag
     6361 catgtcatag cccctttttc cgaataaata gtgttcaaaa gacagcctat cggcaataag
     6421 gcaagatttt ataaactacg ggaagtaatt tccgtaaatc tattcttatt cttttaagct
     6481 gacaagctcg tcaatcacta ctgcttttcc tgaagcaata gaatgatttg ctgcgattcc
     6541 tgtcaaaatc gacaaaatac catctacgtg agttgctgcc cgattccacg gatcttcttc
     6601 tttttcttca ccaaatagat catctaataa acgcggatct cctccgccat gtccgcccgc
     6661 ttcttgttcg acgattacct catatggctc accgaacatc ggatagacat ggatggactg
     6721 aagaacggct gctccttcat cctttttatc tccacctgca ttgatgtaag acttttcgat
     6781 cactttcatt tcgatccgtc ctttgctgcc attgaaagaa acattgaatc cttcccacgg
     6841 catatacgcg tttagcgaat acgtcaaaat cgcaccagtt tcatatttga ccgttacgcc
     6901 tagtgtatct tcaatagaga tatcatcgga aaatacactg cggtcacgaa tatatccact
     6961 gtctttttct gcttctaaat acatttctcg caattcctca ttggctgaca ggtctatagc
     7021 aaatggatca gctttagcta gttcgcttcc atagcatcga ctgtaaaata tttctactcc
     7081 gcgtttctcc gcattatgca tcccataaaa gtttaatcca ccgaatgcaa ataccttttg
     7141 gggacggctg ttcaaccaaa aattcactag atcaaaatga tgggtagatt tatgaacaag
     7201 aagcccgccg ctattgtgct tatttcgatg ccatcttctg aaataatctg ccccgtgttg
     7261 cgtatttaac agccattcga agtggataga aaacacatca ccaatcacat cactttctat
     7321 cagttccttt atcttcgtgt gatacggtgc ataacgataa ttaaaagtga ctcgcaggct
     7381 tcttcccgtc tgtttttgga ccgttattat ttcttgagct ttttcctcat cgatagtcag
     7441 aggtttttcg caaataacat catatccttt tttcattgca cgaatgatat aatcatgatg
     7501 cgttcgatct actgacgtaa taatgacttc agccggccgt acgtcatcca gtagttgctc
     7561 aaattgtgat ggcatacatg tctttacttt tttctgtcca tacttgttca caagtatccg
     7621 atttgcataa tccatccttg tttgagatac atcacaaaaa ccgactagtt cacaagtttg
     7681 atgatacgta gaggcaattg cctcataaaa aaaacgcgct ctcccaccaa gtccgacttg
     7741 tacatatttt ttcttcattt aaagtcattc tccttttctt ttaagcaaaa tactgtgaca
     7801 aatggcagcc ctggatacag taatgcagtg agtaaaaaat catgctgtat acaccagaac
     7861 agtccataca aaaggcataa ataccacaga aaccccttga cgttttttga caacagccag
     7921 atattccttt tgatcaaata aacaagacta tctgctttat cttctttgca gatatcaatt
     7981 agcgtactaa aaaaactatg ggatacaaaa agcaacagac acaatagaaa aggaatcaga
     8041 taccaagctc caatctttcc cactaataaa taccaatcaa ctgcaaaaat aatgacaaac
     8101 agctgaaaca acgtaatgat gaaacacatc cgtttgattt ttcctttcct ccaacatacc
     8161 tttttttctg ccaagtaatg gacagataga taataagaag gatacatcat caaaaaataa
     8221 atcagataga caacacgagc agacagcact aatcctaaag tgaacaaaca tcctagaact
     8281 aaagcgaaaa gagcattact gataagactg gttaaaaaaa tccgacagac atagtagttg
     8341 agcttgtaaa gaaacatctc ttctattggc tttttcatat tcagcccttc agaccgcttg
     8401 tactgatccc ctggacaaga tatttattga agaataagaa aatcagaaaa accggtagca
     8461 gcgacaacgt agacatcgca aacatactcg cgtaagtcgt actagatcca gcgtctgcaa
     8521 ataatttgat ggcaatcgat accgtgtaag atctcggctt gtttaaataa atcaatggtc
     8581 ccatgaagtc gtcccatttc caataaaact ggatgatgat cgtcgtgatg atcgaaggtt
     8641 tcagcaaagg aaaaataatt ttggtaaaga cactatactt gctgcatccg tcaataatcg
     8701 ctgattcatc taactctttg gggatgctga ccatgaattg catgatctgg taaatgaaaa
     8761 atgcttgtcc aaaaaaatgt ggtaaaatca gcggcacata cgtcccaacc aaattcagcc
     8821 gattgtaaat aataaactgc ggaatcaaaa tcacttgtgc aggaatcatc atcgttacta
     8881 acatgacgac gaaccagaat ctttttcctt tgaaatcgat tctcgataat gcgtaagcaa
     8941 tacaagtcga gctcagaact gtccctatcg tcgaaactgc agagatgaca aacgaattcc
     9001 taaagaaagt aaaaaatgaa attccagcaa accccgccca tccttttgcg taattttccc
     9061 attgaaaagt ctctggaatc aaattcagcg aaccactcat aatctcttga tccgttttaa
     9121 aagaacctgc gatcatccat aagaccggat aaatcatgac tagacctaat agcaaaataa
     9181 aaccgtattg aaaccatttc gttactgtat tattcatttc ttcctcctct cattcacaca
     9241 acgacccatt tttttgatga tttgaaaatc agaaaggtga cagctcccat aatcaacagc
     9301 atgatccacg aaatagcact agcatacccc atagaattaa aagaaaaagc ttggttatac
     9361 acataaagag cataaaagtt cgtggcatca ttcggaccac cttgggtaat gataaatgcc
     9421 tgcgtaaaag tcataaacgc cgcgattgtc tgcataacca agttatacaa aatgatcggc
     9481 gaaagaagag gtaacgtgat cttgtaaaac gtctgccatt tgttcgctcc atcgatctct
     9541 gccgcttcat aatacgagcc tgggatctct ttgatacctg cagcaaagat gatcattgcc
     9601 gaaccgaatt gccaagcaga catcaaaaca agagggatca tgaccagttt ttgatcgcta
     9661 aaccaggaaa gcgcaggtgc gcctaatcgt tccaggaaaa tattcactaa cccgttttta
     9721 gaaaacaact cccgccaaac tagagcgata gaaatactgc caccgatcaa actaggcaca
     9781 taatacaaag aacgaaagaa agtcgttcct ttgatattcc tcgttaaaag ataagcaatc
     9841 aatagaccaa agatcagttt cacaggtaca gatgcaaata catagagaaa agtgactcgg
     9901 atggagttca aaaaacgggc atcactcagc atctttatat aattatccaa gccgatccat
     9961 gagactggat ttcccaaacg ataatcggtg aacgaataat aaagtgacaa gatcatcggt
    10021 atcactgtta tcaatagaaa tcctaggatg aatggagaag caaatacgta accgaccaca
    10081 ttgtcttgat ccaagaaccg ttttagtttt tcttttttca tgccttcctc ctgctgctat
    10141 cctagaatgt ttgacgcaaa ctcataaaga ctctctgctg cttcttctgc tgttacttct
    10201 tcataaatga ctttttcaac taaaagattg tattggtctt gaatttccgg attcaaagca
    10261 ctatcaaaga cattcacttc gccgttgtcc atatcggaaa tcatttctaa ataatcaaat
    10321 gtcgcttgca aagttgcatc atctgcacga gcgagctgtt ctcgaatatt cgacatgatt
    10381 ggtacaccac gttctccttt taaaatttca ttggcttctt cactgttttg aaagaaatca
    10441 ataaacttag cagcttcttc tttatgggct gagctttttg ccatactcag catttgcgaa
    10501 gaacgtaaag ggataccaga ttctccatct gcttttctgc gaggtggatt aatcaactga
    10561 atctccatat cttcaggagc ccctgacaat atttctgtca actggttact tgatagaaac
    10621 accattgccg cttctctatc cctaaccgcc tgaaaagaca gatccgtcgt acttgcagct
    10681 ccaccacctg gttctggatg ggcccctttg tctaccagat ttttacgcag ctggaaaaaa
    10741 tctgttagat agtctggatt ttcaaatccc aagctgttag atagatcttc ccgattataa
    10801 aaattcaatc ctttctcaac ttgtggtatt tgaataatac agccagctat aaaatcttcg
    10861 aatcttgaaa tagcatagat tcctaattct tcagtgattt gatagctgat ttgttcaaat
    10921 tcatcccatg tccaatttga agctggttca gggatattta attgttcaaa tatattttta
    10981 ttgtaagcaa tcgcaaacga attcaccccg ttagacagtc caactaattg cccgtcgtaa
    11041 gtcgtcgttg ctaaatagga ttcatctgca ttagaaatat caattatccc ttgctccaca
    11101 tattcatcta atggttcaat ctgattgatg tattgaggaa attgattgtt cagttggaaa
    11161 atgtcccaga tatcatctga tgctgctagt gtacctaatt ttgtgtaata tccttcataa
    11221 tcataaaatt cataatcgat cgtcacatgg ggattttttt cttcataaag ctcgattact
    11281 tttactgttg catcgtgtcg gacttgcgaa ccccaccaag ccatgttcag cgtgattttt
    11341 ttgtcatctt cttgcccaca agccgtcaag aagaataaca taacacttaa agctaagatg
    11401 attctcattc ttttcttcat tctctgcacc tctacttcca ttgttatttt tcaatatact
    11461 gtatttttat acagaacata tttattaaac gatctttttc aaggggaata aaaaccaaga
    11521 cttgccttat cgttctgcct aggatgaaca actcaatact ttcaagaaaa attagatagt
    11581 gctgattctt ctttcatcgc taaaaacact tcttgcttca atgatgggag gataattacg
    11641 caaagaaaaa aggatatcag acaactgccc aatatccttg acatagctaa ataagcatgc
    11701 ttcttcgtgt gcgctcttcc ctaaaaaaca gaaaaataac tagtaattct gtatgaaatt
    11761 aggtacaata tacacgtcga tgcacaagca ttgactatgg caacttgatt ggtcagttcc
    11821 cgctgacttt tcaagccccg acaatttagc tgctactaaa ttgtcgggtg ccttttttag
    11881 tttttattcg tttttcattc tatagaaagc gcttcaataa atcaagacat ttttttgtta
    11941 gaatgctaat aataacaaaa ggttttaact cttcttatgt acattacagg taaaaaaaca
    12001 aaaaaatttc tctttttttt gaattctgaa caaatagtac tggagtacaa aagacgagga
    12061 agagccacta tctgctcttc ctcgtctttt gattctcacc tgttattcat gattcttttt
    12121 ctcagtttcc cgatattttt ccattttacg actaaaaagc tctccgctac ttggtggcgt
    12181 atatgtgatg gcatttgctc ctgcttgaat ggtctcagca atactttctt ccgttggacc
    12241 acctgtcgca atgataggaa gttcaggata ttttttacga aaatggcgta ctgcttctgc
    12301 agtttcttta cctgcactga tattgataat cgaaatacca gctgctaact tttcatctat
    12361 ttctgtatat ttcgacgtta ccgtactgat aactggaata tcaactactc gacaaacttc
    12421 ttttactgtc tctaaaggcg taggaccgtt caaaacgacc cctaacgaac cttgcgcttc
    12481 tgcgaacatg ctcatgtagg aagaacgagc accttgtgtc aaaccaccac ctacaccgga
    12541 gaaaactgga atgtcagctg cctcaataat gcttttagta atcgctggat gaggtgtaaa
    12601 aggatacaca gcaattactg cattcgcatt tgtattacgt atgatcgcaa tatccgtagt
    12661 aaagatgatc gaacggatca attttccaaa tatcttgatc ccgcttgctt ctaaaatgat
    12721 ttccggtact cttacgatat cttttctcaa ttccgtcatg atttctggcg taaattgttc
    12781 tgccatcagc cacttctcct ttgctatctc cggtcatact gattcaattg atacgtctcg
    12841 atgacctgga tgattttttg cgcataaccg gggtctgtcg cataacctgc atcttgcaat
    12901 gcttgtgcgg cttcctgata gttggtggcc gtaatcactt tttcatacag cgcaggattc
    12961 caatctactc cttggacgaa cagttgtgta tggtcatcca tggactgttc ccatgaatca
    13021 tacactttga agtctccttg gatagttatc cattcttcgt taacaaattc ctttgtttcc
    13081 aggcttactt tcttctgatc cccataagcc ttgatcccga aaagattatt gtatttgcta
    13141 gccaaggtac tttttcccca atttgattct aatatagctt gtcctaaaat gatactagga
    13201 agcactccat aaccatcttg tagttcttgg gcatgcggaa caagccgttc aataaattgc
    13261 tgatgggatt gcgcttcatt ttcttgctga ttatcagtaa aaggagaaga cagattcttc
    13321 aaggaaaaaa caaaggctaa gagtatcact gctacaccgg caaccactgc tggccaacgg
    13381 atattcttgc gcttttgctt tttccacttt tttttcgcca tgatcaattc ctacttttca
    13441 tttaattcat tcagatattc ttctagcgtc aattggtgtt tggtgatata ctcagcgttt
    13501 tctttaccga cataacgtaa gtgccaaggt tcatatgtga tcttagttat atcttcgtgt
    13561 ccttttggat aacgaacgat aaatccatac tgcgcagcat tatctgcgat ccatttagct
    13621 ccaggctgat ctccgtaact tgcatccaat acagtagaag gataactgtt gtaccagttt
    13681 tgatcgacga catcgactgc cagacctgtg tggtgttcgc tgtatcctgg ctccgtaatc
    13741 gtttctttag taatctttgt cgcctcctct tctgatacac cttgacgact catcacatct
    13801 tggacatttt gttcgaaaac ttgttgttgg gatgatacag accggtaagc tgagaccatc
    13861 actaatggaa atccagctgc ttcagcagcc ttggcaaatg cttcatattc tggagcaatg
    13921 cgtttgtcga tcaagtatcc gttacttaat gatgccaatt gagtagactc atcaatttct
    13981 ttttctaatt tgtgatctgg accaaccaaa actagcttcc aatcgtctgt tttaacatct
    14041 ggcaattgtt tggacgtacg atcttttgtt tctttgtcct ttaccttgct gctggttgtt
    14101 tgactgttct tttctttact agcagttgtt ttggtgcttg ttcgttcgac tgcttgattg
    14161 ccggcttgaa catgcgaatc atcatcgcta aaaataacat agcccattgc tgcgatcata
    14221 atcacaactg ctccaaatcc taaaaattta ttcacttgaa aaatcctttc gttgttcttc
    14281 acgttcccca ttcgcctcat gaacgtaagt ttcttccaga ttttcattca cccaatcgag
    14341 aagttcgatt ttttctcctt cgatctgttt ttgaacatct gctggcagac gaaaattcaa
    14401 aatatcatca tagccccatt catcatattg aatacttact ttcaagtcaa ggtatctacc
    14461 agcctgctga ttatttttca aagggatcag ctcgactttt gctgctttgc tgctaagcca
    14521 tttttgcgcg atgcgtgttt tgatttgctt gtactctgca acggcaacgt ttcgtttttc
    14581 gggaaaaata atcgtttgac gcaaaatctt ttgcgttagc atccattcat aatcagtgaa
    14641 aagatttttt actttctgca tcgcttcaga tggcagattt ttctcgccat ctttccattt
    14701 ttgccattgt tctggactga tcagcaagta ttcatctaaa aaattttttt cagtttcaaa
    14761 ctgttctaat aatacactca taataagatc aatatatact tgatgcacgt ttatcccctc
    14821 cttttaacta ttctacttaa gttttgatca aaaagcacct cttaaatcgc tgctttcatt
    14881 ttttttaatg tttcaagtcc tctcctcttt attcttcgtg atttttgtta taataataga
    14941 cagacaagaa actcaatcca actatgaagg agcgttttca gatgaaaaaa tatcaatggg
    15001 gaatcgttgg tcttggtacc atcgcacatg agtttgccga aagcttcaat caagagacga
    15061 gcgaactaac agcagttgct tccagaactt cagaaaaagc ggaaaacttc gctcaccgtt
    15121 acaatattcc aaaagcttac ggaagctatc aagaaatgtt agacgatgct gaaatcgaca
    15181 tcgtgtacat tgctgtacca aatagacagc atatcgacca tatcttggca gcattggaag
    15241 caggcaaaca cgttctatgt gaaaaagcca tcacgatgaa taaaaaagaa ctggctgacg
    15301 ctatgcgctt agcagaagaa aagaatttga tcttagcaga agcgatgaca atcttcaaca
    15361 tgccacttta tcagcagtta cgctcaataa tggatacagg aaaactgggg gctttaaaaa
    15421 tgatccaagc acctttcggc agttacaaag aaccagaccc taaaaaccgg ttcttcaatc
    15481 cagaattagc tggaggagct ctgttggata tcggtacgta tgctgtatct ttcgctcgtt
    15541 tctttttgag ctctcaacct gaagtagttg cctctacaat ggttcctttt gaaacaggcg
    15601 tggacgaaca atccgtcact atcttgcgta acaaagaaaa tgaacttgct gctgtcagct
    15661 tgacttttca ggcaaaaatg ccaaaagtcg gtatcgttgc ctttgagaac ggttatgtga
    15721 cgattgctga ttacccgcgt gctgatcgtg cggagatctt atttacagat ggtacaaagg
    15781 aattcatcga aagcgggaat acatctgaag caatgaatta cgaaataaag aatatggtac
    15841 acatgattga aggtgacttg cccaatcgct ctctcttctt gacaaaagat gtcatcgaaa
    15901 tcttggatca aatgcaagtt ctatggaaaa atatgtaatt ttaaaaggtt gtgaaaaagc
    15961 tgttctgcat caagtaataa gaacagccaa acaaaaatag ctcctcctat ttttcgtttg
    16021 gctggactta ttaccgcaga ggaaagcttt tgaacaccgt ttaagaaaga ggttgtgagc
    16081 ctaccgttca gctccgagtc acaaggagca atttcaaaaa acagcttctc atgtttgttg
    16141 aatattgtga cttgtgaccg aggagttgac aggagaacac cgtttaaaga agaggttgtg
    16201 aaatcagctt tttgacctga atattagctg aattcacaac ctctattttt ggattttttg
    16261 ttgggagaat tctgccttga tttcaataaa acttttaaaa gactgcaaaa actggaacaa
    16321 ttctgctcga tcctcgaatt cagggcgact agtcggcaga ggcatttgcc gatacaatac
    16381 ataaacttct tcaatacgtg ttaaaatttg tctgccatca tttgactctg aaaatgtttc
    16441 tgcagtataa atcaataaac catagatatg ttttccataa taagctggtt gctggattct
    16501 ctctagattt tccagcatgt ctttaatcac attggcctgt gctcttctca tagagaagta
    16561 agtttcgtag tatagcggct gtctgagcca gtagttttct tgatgttctc tggcatcttc
    16621 ttggctttcg cgaatgaatg tcagtaaatg ttcgcatttg atctgcacat cttctttatt
    16681 ttctgataaa agaaattctg ccatttgtct caaaatattt cgaaattctt tttcgatctg
    16741 tatttggttt tccttcagct gcttcgtacg atctggcatg taaacatttg caagcaaagc
    16801 aaatactaat ccaatcgcca ttaatcccgc ttcattgccg atcagctgcc aagacatgtt
    16861 ttcctccact aaataatgag tgaccaaaac cgaatttact actatccctt cggttaattt
    16921 gaagcgagag gcaagcggga tgaacaggaa taaaaaaaga ctgaagccaa aaatagtata
    16981 cccaacagca aaaaaactga acagtgctgt tgccgtagct aatataaagg ctgcgattcg
    17041 attcatgccc gtacgcaatg tagagcgctt ggtatttcct acacttaata atgcaatgat
    17101 ccctgcagct ggccaataca acagcgataa gctacccgct gtgaccatcg aaaagaagac
    17161 actgatcact gttttgactg ttcgcattcc tatacgcatt tacttccccc ttttttattt
    17221 taattatact tgaataatga aaaactagct atcagacaaa agtttaggta tgatagtaaa
    17281 aagaccaaaa aggagaatct ctatgcaatt tggccgtttt cgactaggta tgcgtacgat
    17341 caaaagtgcc ttagctgttt ttttatgtat cttgtttttt catttgactc aacgaggaat
    17401 cccgatgatt gctgcattat ctgctgtttt ttctttgcgt caggacttga ctacaaccgt
    17461 ttcttttgga aagtctagga tcatcggcaa tacattaggt ggtacattag ctatcattta
    17521 tttttttgtc aaaagctatt ttcacaatga ttttttggta gaattgatct tgcttcctat
    17581 tctagttatt attgtgatcg tcgtgtcaga tggtattaac aataattccg gtatcatttc
    17641 cgcaatagct acgttgttgc tgattgcgtt gagcatccct caaggcgaat ccgctttgta
    17701 tgctatccaa cgtgtactag atacttttat agggacattc attgcaatcg gtatcaattt
    17761 ctttcttcgt cctcctgaaa cagaaaagaa ggaagaacta tcagaagatt tggtcgaact
    17821 ccaaaagaaa gaacgattgc taagaacaaa tttacaagag atagaagcta agatccaaaa
    17881 acaaaagaaa aatagcgagg actaattttc ttttgcaata aaataaaaaa atggagagaa
    17941 gaactttaaa aagtcttcct ccatttttga ttgaacggtg aagtgtacta ctttattctt
    18001 ccttcatcga gttttgttct gcctcttttg gcgcttcata catatttact tggctagtag
    18061 tcccacgtgt cgacaaattc tctacgattt ccttcaagtc aagtcctgtt gtcgctttta
    18121 gtgtttcttg agtagaagaa agcaaatttg tggcataatt tgtcactcgg ttcgctccac
    18181 tggtttctcc tgaactgctt cctgtatcga caacagagat tttttcgata tttcctagcg
    18241 gctgtgctgc ttcgcgcatc aattgcggta gcatatcgat aaccatactc aagacagctg
    18301 cttcgccata ttccttgaag gcattggcga tcttttgttt tgcttcggct tctgcttttc
    18361 cttttgctag tgctgcttcg gcttctgctt gtccagctaa acgtgtctta ttggcttccg
    18421 cttctgccag tgcttccaca cggaatcgtt ctgcttcggc ttcagtcact tctttgactt
    18481 tttgagcttg tgcttcttgt tctttagcgt accgatcggc atctgctttt ttcttcactt
    18541 ccgaatcata ttgcttttca cgacgtgtga tttctttttc ttccagttcg atttgttttt
    18601 gacgttctac gattttaatc tgcatttcct gttcgattac ttgttgttgt gctcgggcac
    18661 tttctaaatt gtaggcttgg tctgcttttg ctttagcaac atcttgttct tgtttgtagg
    18721 ttgctaattt cagttctttt tcttttaatg attctgcgat ctctgtttgt cgctgtaatt
    18781 cagctgcttg tgattctttt tctgcttgag cttttttgat acgcgtttct tttagagctt
    18841 ccgcttctgc tatatctgca tctcttttga cttgggcgat tcttggtttc cctaaagagt
    18901 caagataacc gtttttgtct ctgacctctt tgatagtgaa agaaacgatg atcaacccca
    18961 tttttgcaag gtctacagaa gcgacttctt gtacgctttg actgaactta tcgcgatttt
    19021 gatagatttc ttctacagtc atagaaccaa gaatcgagcg caagtgtcct tctaatactt
    19081 ctcttgcttc attttccagt tcttctcttg tcttgcctaa aaactgttct gctgctgtag
    19141 caatctcttc tacagatgaa ccgattttga tgatcgaagt accatcacac atcaccggta
    19201 cgccttgttc cgtatacact tcaggggtgg agacgtccaa tttactcgat aatagactga
    19261 tccgattcga acgttgaaaa actggcaaga cgaatgcgcc acctccacgc acaattttga
    19321 ttttgttatt gctttcatca atgtgcacat ttttgcttcc taaataactt ccactgatga
    19381 tcaacgcttc atccggtttt gctgtctggt acttcgctac aaagacgatc agcaacatca
    19441 gtaaaatcaa agctgcgatt gcgatcgcga taaaaacaac tggtatttcc atttaacaca
    19501 cgctccttta agcttttatc atgctttcat aaggcatgac ataacagatt ctttccttga
    19561 tctcaatgat caatactttc gttccccgct cagctgtctg ttcttggggg ctgtaaaaac
    19621 aagctggacg actaatggaa ccggtaacac ttttcaactg aatttctccc atacctcgta
    19681 cagggatcgg tgtgatcaca acagctactt gtccttccag agttttttca gaagacgaca
    19741 tcgttgattc ggcatgtttc atcggcatca atatatagaa attaagcaaa aataccaaca
    19801 ctatcgatat gcctccacta gcaataaata aaaataaaga tgattgatct gttaaacgct
    19861 cacctagaaa accaaataag cttgtgaaag ttaaccaagg gataataagc atcggatcaa
    19921 gcgggccatc aaaatcgaat acatctccaa aaataatcaa taggactgcc aatcctgcac
    19981 aaatcagcaa tgtataccaa taaatcgtct caagtgcgat tccccctatc atatacacgc
    20041 ctccttccat ttctacgtct atcataccaa tgtttgaaaa ttctgtatag cttcttttac
    20101 cgactcagtg gtgtttttta taggaaggtt gtgtttatcg ttgacaattt gttaaatttt
    20161 tgttttcatg ttaaaatttt cacaataaat tctttcgagg tagcctatgt ttcctttttt
    20221 taagaaaaaa ccattaaagc tccagaacac gatcatcctt gtcgtttgtt tctccacatt
    20281 cgtttctttg attgtttctg ccatattgat caggaatttt attctttcga tgaaccgatc
    20341 tagtgtgtca gataaaatct ctagcattgc taaaatcgtt gccaatgata aactcatcca
    20401 aaaaaagctg cagactggtg acccgacaca tgcgattcaa ggaataacaa atgaaatcat
    20461 gattgcatcg aatttagatt ttatcgttgt catggaccct gaaggcattc gatattctca
    20521 cgcagaccca agttacatcg gtcttccttt ctcaagtcat gaagatgtga aaaaagtgat
    20581 tggaggacaa gaatttttct ctgaaaaaga aggaatgtta gggttcggct tccgctattt
    20641 cgtccctatt tattatgatc aagagattat tggtgcagtt tgtgttggct taacaaacaa
    20701 cacgattgac aatcaagtca aagatggaca aaaaatgatt gttttttcat tgattattgg
    20761 acttagcgta ggcatcatag gcgccgtttt tcttgcccaa aaaatgaaaa aagtactgct
    20821 tggacttgaa ccacaagaaa tagcagaaca gttaagtgaa aaaacgatta tcgaaaatga
    20881 agtagatgaa ggaatcttag ccatctcttc tgataaaact atcctcttga tcaatacacc
    20941 tgcaaaaaac attttctacc aaacagagca gctattggat ttcgaagtag gaaaaaaatc
    21001 agtgataatc tatatgacgt tttgtttaaa gagacgattg agcatcaaac gaccgttcgg
    21061 actcaatcca tgtatttaaa tgggatagaa actatttcta gcgttacacc tctttttagc
    21121 aatgaccgtt ttttaggagc agtcgcaact ttacgaaatc gatcagaagt aatgaaatta
    21181 atggaggagc ttggggggac gaaacaatat ataaactcca tgagagctca aacccatgaa
    21241 ttcatgaata aacttcatgt catttctggt ttgattgatt tgaagaagta tgaagaagtc
    21301 acccatttta tccagcagct aaatcaaaat tataaaaaag agattggcca agtctcaagt
    21361 ctgatcaaag tacctgcaat tgccggtttt ttattaggca aaataaacga agccaaagaa
    21421 caatctgttg aaatgctgtt agaaagcgat tcttttatcc ctaaaatgga gatggatgac
    21481 tccatccatt cacttttgca agtgttaggg aacttacttg ataatgcaaa agaagccgtg
    21541 ctacaaaaac atgaaagaaa cggacaggtc cggattcatt taaactatga cacagaagct
    21601 gaagtattca tcgtgaccgt ctgcgatgac ggtgtcggga tatcagaaga aatctcagaa
    21661 aaaatattta cgctaggttt ttcgacgaag ggaatcaatc gtgggtttgg attgaatctc
    21721 atccattcaa tcgtcaaacg ccacggtgga tttttagaat tttccaaaca aacaaatggc
    21781 ggtacaatcg tctatctaga attaccaaaa aaggaagatc aaaatgatga caaatgtcct
    21841 gataatcgaa gatgatccaa tggttgcaga attgaatcgt acttttgtgg aaagcatccc
    21901 taatatgaac gtaatcgaaa gtttcagaaa tgtagaagaa ggaaaaaaat atttcagaca
    21961 aaaaaacgca gatctgctgc tgcttgatgt atacatgcct ggcgaaagtg gtatccattt
    22021 tttatcttgg cttagacagc aaggaaatga tatcccagtg attttgatca ctgctgcaga
    22081 tgatatcgaa accataaaga atgtgatccg ctacggtgcc ttagattatt tgatcaaacc
    22141 gttcactttg caacgttttc agctggcgat cgaaaagtat cttgctttct ctcagacaat
    22201 ccaaacgact gaaaaagccg atcagaaatt gatcgatcaa gtattcaacc acaccactcc
    22261 cattcacgaa ataccatcat tcatcgattt gcctaaaggt ctgtcaaaac tgactttaaa
    22321 aaaaataagt gcatttattc taaaagaaga tactattttt tcaacaaaag aactggctca
    22381 aaaaagctca ctgtcacgta tatccgtcaa gaaatatttg aattttttag tagaacaaga
    22441 tatattgaac gaaagaatca aatatttgga aatcggccgg ccgctaacct gttatgaatt
    22501 gacaaagaat gggcggaaaa agctcacaga ttactgttga gtcatcgaat tatcccatac
    22561 aaaatagtcc aagtatacag aagtaacaac tgtttacttg gactattttt aaacatttta
    22621 ttgacgaata tccatgtttt cttatcttaa ttgacgggct ttaggaagag atacctcatt
    22681 tttcgttttt ccagtttcta ttatttcacg aaagttctcg aaacttgtcg aaatcatatt
    22741 tgataatgcc tcatctgtat ttgaacctac atgcggggtt acaagaactc tagggtacat
    22801 ttctactaat tgctggatag cagggtctgg aatcgtctcc catggcttga aggatcggaa
    22861 aaaaacctct gtttcatttg caaaaacatc ggttgcaaaa ccagctaaat gattgctttt
    22921 caaagctctt aaaatagctt cattatcttg aagctctcca cgggctgtat taatcaagat
    22981 gctacctttt ttcatttgag ctaaaaatcc ttcattgatc atttgatcgt tttcacctgg
    23041 gatatgaggt acatgaatac tgacaatatc gcttttggct aataactctt caagcgagtg
    23101 gaacgtcaat acttttttag cagcttctgt ctgatgaata tcgtagccga tcactttggc
    23161 tcctagtccc ttaaacaaaa cagcttccgt caaccctatc ctgcctgttc ctatgatccc
    23221 tactgtgcaa tttctgattt cacgactaaa catttgctca tccactcgaa aatctttgaa
    23281 agatgttcgg atcgtcgtat acgcagtatt tctcaaaagc atcatggcaa aagtcaaaga
    23341 taactctgct atcgcatttg gcgaatacga tggtacacgg gctactgtca taccaaaatc
    23401 agctgccgct tgtagatcga tatgattgac tcccacagtc cgtgtaaaaa cataacgaat
    23461 cccatattcc tgcatttttg caagattggt ctcatctgct atacaatttc ccctcaacaa
    23521 tacagcatca tggtcctttg ctgacacgat attgtcatgt gtcaacagtt cttcataaag
    23581 actgagatca taatggtaaa tattcaattt ttcaaaaaaa tctatctcgt tcggacgaac
    23641 accgtaacat gcgattctca tactttcttc ctccatttct tatgaaaata aacctatgcc
    23701 atgaatcatt tgtaatacaa cgatccatac aggtgtcagt accacagcaa aaatagttga
    23761 cagtaaggat gcattggagg ctaaaagtgc ctccctatca aaactgatag cataggctgc
    23821 tgccactgtt gcagctggtg tagccatcat gataacgatt gttgccagtg cttcaaaatt
    23881 gactggtaga atattcgttg ccgtcaaaac tgctagaatc acgatattca atgcaggtac
    23941 aaataccact ttgactagac tgtaatacca tgaagttttt tcagatgcag cttttttgaa
    24001 gcttacttca cctaatgttg cgccgattgc tagccacgcc aatggtgaac ttaaaccagc
    24061 taaataatcc atcggctgaa atagccacgg tgcagtctgg tcaattcgca aaaacgctac
    24121 ttggcttatc tctccttctg cacctgtaac tgacacttgt ggcagatacc cttggaacag
    24181 ccaaatgaaa aggccggcaa aagtagcgat aatgattgga ttgacgaaca tcgctttgat
    24241 atttttagct tccatcttca agccactcat ttttatgtat ccataagaat acaaaaagat
    24301 tcggtagcca atattgaaaa ttgaggaata catcacgccg acaggaccat aaatcgcact
    24361 gacgataggc gttccgaaaa aggtcgtaga accaaagatc gtcaggacac gcaacgttgt
    24421 ttgcttatcc cctttatagc ttaagaaaaa aggttttgaa actagaataa gaataatata
    24481 aataactaat ccccaaatca agacattgat tccttgcatc agtaattctg tattgatatc
    24541 ttgcatgaaa gctcgaaatg ccagtgctgg caaagccact gttaagacga ctttcgatag
    24601 aatttttcca acagattcag aaaaaatccc cttttttcta caaacaaacc ctaataatat
    24661 aataaaaact gttgaagtga ttgcactgac aatcgacata tctgtcaaag tcgatcgaaa
    24721 aatgtcaaat aagttcatct ttctcctcct aattatgttc atttattcac aataaaaaaa
    24781 gcttttattt tgctaatacg tattaacatt tttaatttta tctttacatt gttacttatt
    24841 gaacaatagg aaattaaaga aacttttgaa acttatgtaa agtgattttt actagaacac
    24901 aaaaaaaacc ttaaaaccaa acttaagaag tttagtttta aggttaactt aaattatatt
    24961 atgcgtggaa acgttccacg ccatctagat aagttgcttc caatgtcata tcagggttca
    25021 atacgataaa gtctgcatcg cgtccttgag cgatttttcc acatgtatca tcgattttac
    25081 agctgattgc tggaatcaga ctagccatca tgactgcttg ttctggtgtt gctaatcccc
    25141 agtctacaac atttttaatt gcttctttca atttcaatat acttccagct aagttgccag
    25201 attctagacg tgctgttcct tcttttacta ctactggaaa ttcgcctaaa ttgtaatttc
    25261 catcaggcat cccaccggcc atcatacagt ctgtaattaa tgcgacatga tcatgtcctg
    25321 ctttttccat taggattccc gcagcatttg gatgtacatg atggccatca caaatcaatt
    25381 cagaaaagac atgttctaaa gataataacg cacccaccat acctggttcg cgatgattca
    25441 atccacgcat accattgaaa gcatggacaa atacacttgc gcctgcttca acagcttttt
    25501 gcgcttcttc tagtgtagca ttactgtgtc ctagagaaac aactactcct tcttcagtca
    25561 cttgtttgac aaactcttct acaccttgac gttccggtgc taaagcaatt tttttgatta
    25621 aaccacctga agcttcttgc cattcatgga aagtatccaa atcaggatcc ccgaaataac
    25681 ttgggttttg tgcccctttg tgttcttctg tgaagaaagg accttcaaaa tagattcctt
    25741 tgattttagc tcctggtgct tcctgataca ttttgccgat tgtctcagct acatctttta
    25801 aacgttcttt gcttgacgtc aatgttgttg gtaaaaatga agtcactcca caagataaca
    25861 gaccttcaga catcactttg atgccttctg catcattatc cattacatca tgattcatat
    25921 agccgtgaat atgtgtatct accaaaccag gagcaatcca tttgccgctt tggtcaatga
    25981 tgttgacttc tccctcaggt agttctttgg tgtattcacc aaaaagtcca tcggtaattt
    26041 caagatagcc tgcatgtttg acacctgacg ctaaaaagaa tttgtcagca tagataaaag
    26101 ttctcattct attctctccc tttgtttttc tacctctaaa gtactcttat ttagagaaga
    26161 agtcaagaat ggtctacacc atttacaaat tttttgaaat ttgtttcaca gcttgtgcta
    26221 agccttcata gaatgctgct ctttctggtt cttctttacg cttgtatatt aagcttttaa
    26281 gcacaaataa atcattgagg taatagtagc tattcttctc ttgagcccaa tagattcctt
    26341 gattcacctg ttctaacgct tcgtcgattt cattttgatg gaataagaaa tttccataat
    26401 tataaaaaat ttgcgaaaat tcactttttg atcgttcatc agctgattga tgcagcagtt
    26461 ggatgcttcg actcaaatag tagcgtgctt cagccgtttt tcctgccaca ccatatattt
    26521 ttccgataca actaatcagt tgtatttctg tgtcagaaac atggattctt tctttttggc
    26581 tagagtagct taatgcttct ttcaaataat aaagggactg agagatattt tgacgcaacg
    26641 tgaattcgca aacaccgaga taataataat agcgttgaaa gtcagttgct tgatacagat
    26701 tttcagaaat atcagaagat tttagtactt gttctaactt ccgataatca cgtttttgga
    26761 aacaactatc caacagttca aataatttat cgtttgtccg agtagttttt cgagagagat
    26821 tcatcacatg atcaatcgtt acccctagcc gttgacaaat ctgcatcatc accaatacat
    26881 tcggcagttc ctcattattt tcgatccgac ttaatacact ttgtgaacaa atatcatgcg
    26941 aaagcatttt ttgcgtcatt ttttgttctt ttcgaatctc tttaatgatc gttccaaagg
    27001 actcgattaa cgtttccata agtatcctcc ccaaaatatg cgtattcgca ttctattcgt
    27061 attttacttt aggaagtcgc aaacttcaag aaaagacttg caactaaata atatacttta
    27121 gttatttaag aaaactccac tagaaagaga gcctcagtgt gtttgtctgt ggccctccta
    27181 ctgaaaaatt tggtttttaa aatcattttt ggcgataggt tgctaggaat tctctcattt
    27241 tcttagctgt ttgtttcaaa tcatccattt taggaagata aacgattcga aaatgatctg
    27301 gctggttcca attaaatcca ccaccatgta caagtagaat atgatgttca tgtaaaaagt
    27361 ccaaaacgaa tttttcatca tccaaaatat tgaatcgctt tgtatcaatt tttgggaata
    27421 tataaaaagc agcttttggt tttacggctg aaagaccagg aatatcattg attgcattat
    27481 agatatattc tctttgttca tagatccttc cgcctggcag gagcagctca tcgacacttt
    27541 gataaccgcc tagcgcggtt tggataattt gctgagacaa tacattggaa cacaaacgca
    27601 tggaggacaa catattcagc ccttctatat agcctttgac gtgtgactta tctccactta
    27661 ggaccatcca gcctactcga aatcctgcta cacgatgaga tttggataga ccgttcagcg
    27721 taacaacgaa caaatcaggc gctaatgtag caatcggaat atgttctaga ccatccatca
    27781 ctaagcgatc atagatttcg tcggaataaa taatcaggtt attttgtcga gctacttcaa
    27841 cgatttcttc taataattct tttggataaa gtgccccagt aggattatta ggattaatga
    27901 taacaatagc ttttgtccga ctcgttattt ttgatttgat atcatcaata tcaggatacc
    27961 attctgcctc ttcatcgcaa atataatgaa caggtgtgcc tccagctaat gcaatagaag
    28021 ccgtccacaa cggatagtcc ggcattggaa ccagtacttc atctccattg tccagcaacc
    28081 cctgcataca catcgtgatc aattcgctca ctccgttgcc ggtgtagata tcattgatcg
    28141 tcacattcgg aaaatgtttc agttggcaat attgctcaat tgcttttcta gcagaaaaga
    28201 tccccttgga atctgagtag ccttctgagt cacgggcatt catgatcaaa tcacgaatga
    28261 cttcgtttgg tgcttcaaat ccaaaaggtg cgggatttcc cgtgttcaat tttaaaatac
    28321 taatgccctc ttcttgcatc cgctccgctt cttctagaac gggaccgcga acatcgtaac
    28381 tgacaccttc taatttgttg gatttttcaa attctctcat cacttagcca atccctcatt
    28441 tcaaaaagtt agaactttcc aaattttttg ttatttacta tttcaatatc atactccatc
    28501 ctagaaaatt ttgccactta tttaggaaaa acgtaagtat taaaaaaaca caaacaagcg
    28561 ttgagaactt aattgtcatg atagtcattc catagattcg ctgcccaatc cattgcaatt
    28621 ccacaaatga ttcctagcat aaaaccaagc aaaaaacgtc cgaatgcaag tccaatcaat
    28681 acacctaaga tcattcccag tcctgaaaat tctccgtcat atttctccat cttaataagt
    28741 cctcccattt ttgagcttga caactatgta aaacctcgct atcattagtg tgttattatt
    28801 acgcagatgt gttggaattg gcagacaagc atgattgagg gtcatgtgag cgttagctcg
    28861 tgtgggttcg agtcccatca tctgcactac aactcgtgaa gttaattttg cttcacgagt
    28921 ttttttgttt gaacgtttct ttatgccatt atatacatat cactgtatcc tttacaaaaa
    28981 gaacgtacaa tcatgtaaac agcctgaggt gagtatatga aggtcggaaa caagctactc
    29041 gtagaaactt gcaagtgtta aaacaattaa tcgaaaaacg agtaaaatcc ctcacctaat
    29101 actaaagcga gggatttttt gtatattatc tgtttatcac cgttattata aaggtacaaa
    29161 taccaagcac ggttaatcca aattgcataa attcattttt ttgtacactc atgcttttca
    29221 ttagctcttt aactgccatt agtactaaga tggcgataac aacataaagt atatagtacg
    29281 tccgcattcc ggaagcccat actgtgggag aaaatcccat aattaacctt gaacaaaatc
    29341 ccattatcat caaaataact aaaaaaatag aagttttctt attgtcaaaa cttaaataaa
    29401 ttccaacaat taaacatagt aataatgcca agactactaa agtagctatc caagtacctg
    29461 gataaaaaag tgacagtttc gttcctaact ctgtaaagag attattcagg ttactactac
    29521 tccaaatcat tgccctttta tttccattga cgtaagtaaa gctttgaccc attgtattac
    29581 caaaataaat aatcaggttt aagaaaaacg gtaatgcagt caatatacgc acataatagt
    29641 tttgacattt cctatatgtt agaaggaaaa ttaagaaaaa tagcaataaa aataagatat
    29701 tcatgtctaa aaaaaaggct ctatactttt tgatgttggt gaacttcacc aacatctttt
    29761 ttgtataaaa aaatatagaa aagacaccct gaaatccttt agaattaatt tggctaccaa
    29821 ttcataggag gattcaagat gtctcatact cagcttatca aagataccct aaatattcta
    29881 gacctaaata tctatttcga ggaaaattgt ttaactaaag aaaaatacaa agggcaaatt
    29941 tgcttgattt acaaaggaac tcttctgtac aagccagaag agtgttccca ttgtctttgt
    30001 gtcgtcccct ctaggatcat tcgttggggg acgacaaccg ttcggttgtt actgaatgat
    30061 gtgtctgagt atcgcactta tctggagctg aagaaacaac gatttaaatg taagtcttgc
    30121 caaagaacat tcgtagcgga tacctctgtt gctgaaaaac actgtttcat tagtcaaaaa
    30181 gttcgttggt ctgtcattgc tcgcttaaaa gagaatactt ccatgacgga aatcgctcgt
    30241 cagaaaaata tttccacttc ttcggtctat cgtgtcatga agcgattcta ccgcccattg
    30301 aatcctttca aacagacttt gccaaaggtc ttatgctttg atgaattcaa atcggttcga
    30361 agtgttgcca gtgcaatgag ttttatcatg atggacggac aaagccatgc attattggat
    30421 attgtcgaaa atcgacgctt gccttattta gaacgctatt tttctcggtt ttcattagcg
    30481 actcgtgaag ccgttcaatt gattgttatt gatatgtatg cgccttatgt ttcgttggtg
    30541 aaaaagcttt tcccgaatgc tcagttgatc atcgatcgtt tccacatcgt ccaacatatt
    30601 ggcagaactt tcttgaatca tcgagtgaaa gaaaccacgg tacgacttaa aggaaattcc
    30661 cactctcaac gagggttagg gaaaaaattg aagcgctatt ggaaactcct acaaaaagaa
    30721 gaagcaaagt taaactatga aaaacgggtt tggcgtgcca gttttaaaga ttatttgact
    30781 gaaagtgaga ttgccgatcg actgttagct gcttgtccca acttacgcca aggctatcag
    30841 ttataccaag acattcttta tgcggtaaag aaaagagatc agtcactatt tgaggattgt
    30901 ttaactagag acattagcgg tctgccagaa acctatacaa ccactttacg aacgtttaaa
    30961 aagtttctgc cacagatcca aaatgcgctt cactacagct attcaaacgg accattggaa
    31021 tgcttaaaca accacatcaa agtattaaaa cgcaatgcgt acggctttcg caacttttac
    31081 aatttcaaa
//
LOCUS       DAZKNV010000032        30206 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000032 DAZKNV010000000
VERSION     DAZKNV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.032"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..125
                     /locus_tag="ACG8M1_001604"
     CDS             <1..125
                     /locus_tag="ACG8M1_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0422321.1"
                     /translation="NQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLT"
     gene            complement(181..2544)
                     /locus_tag="ACG8M1_001605"
     CDS             complement(181..2544)
                     /locus_tag="ACG8M1_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFQ0422322.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2709..3213
                     /locus_tag="ACG8M1_001606"
                     /pseudo
     CDS             2709..3213
                     /locus_tag="ACG8M1_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3321..3668)
                     /gene="rbfA"
                     /locus_tag="ACG8M1_001607"
     CDS             complement(3321..3668)
                     /gene="rbfA"
                     /locus_tag="ACG8M1_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFQ0422323.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3695..6001)
                     /gene="infB"
                     /locus_tag="ACG8M1_001608"
     CDS             complement(3695..6001)
                     /gene="infB"
                     /locus_tag="ACG8M1_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFQ0422324.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(6014..6325)
                     /locus_tag="ACG8M1_001609"
     CDS             complement(6014..6325)
                     /locus_tag="ACG8M1_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFQ0422325.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6322..6615)
                     /locus_tag="ACG8M1_001610"
     CDS             complement(6322..6615)
                     /locus_tag="ACG8M1_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFQ0422326.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6637..7812)
                     /gene="nusA"
                     /locus_tag="ACG8M1_001611"
     CDS             complement(6637..7812)
                     /gene="nusA"
                     /locus_tag="ACG8M1_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFQ0422327.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7836..8309)
                     /gene="rimP"
                     /locus_tag="ACG8M1_001612"
     CDS             complement(7836..8309)
                     /gene="rimP"
                     /locus_tag="ACG8M1_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFQ0422328.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8453..12805)
                     /locus_tag="ACG8M1_001613"
     CDS             complement(8453..12805)
                     /locus_tag="ACG8M1_001613"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFQ0422329.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(13017..14726)
                     /locus_tag="ACG8M1_001614"
     CDS             complement(13017..14726)
                     /locus_tag="ACG8M1_001614"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFQ0422330.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14794..16062)
                     /gene="rseP"
                     /locus_tag="ACG8M1_001615"
     CDS             complement(14794..16062)
                     /gene="rseP"
                     /locus_tag="ACG8M1_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFQ0422331.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16223..17023)
                     /locus_tag="ACG8M1_001616"
     CDS             complement(16223..17023)
                     /locus_tag="ACG8M1_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFQ0422332.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(17020..17832)
                     /locus_tag="ACG8M1_001617"
     CDS             complement(17020..17832)
                     /locus_tag="ACG8M1_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFQ0422333.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(18027..18584)
                     /gene="frr"
                     /locus_tag="ACG8M1_001618"
     CDS             complement(18027..18584)
                     /gene="frr"
                     /locus_tag="ACG8M1_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFQ0422334.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18587..19309)
                     /gene="pyrH"
                     /locus_tag="ACG8M1_001619"
     CDS             complement(18587..19309)
                     /gene="pyrH"
                     /locus_tag="ACG8M1_001619"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFQ0422335.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19445..20326)
                     /gene="tsf"
                     /locus_tag="ACG8M1_001620"
     CDS             complement(19445..20326)
                     /gene="tsf"
                     /locus_tag="ACG8M1_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFQ0422336.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20425..21207)
                     /gene="rpsB"
                     /locus_tag="ACG8M1_001621"
     CDS             complement(20425..21207)
                     /gene="rpsB"
                     /locus_tag="ACG8M1_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFQ0422337.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21566..22045
                     /locus_tag="ACG8M1_001622"
     CDS             21566..22045
                     /locus_tag="ACG8M1_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0422338.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22262..23353
                     /gene="phnW"
                     /locus_tag="ACG8M1_001623"
     CDS             22262..23353
                     /gene="phnW"
                     /locus_tag="ACG8M1_001623"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFQ0422339.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23346..24131
                     /gene="phnX"
                     /locus_tag="ACG8M1_001624"
     CDS             23346..24131
                     /gene="phnX"
                     /locus_tag="ACG8M1_001624"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFQ0422340.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24477..26168)
                     /gene="argS"
                     /locus_tag="ACG8M1_001625"
     CDS             complement(24477..26168)
                     /gene="argS"
                     /locus_tag="ACG8M1_001625"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFQ0422341.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26590..27537)
                     /gene="arcC"
                     /locus_tag="ACG8M1_001626"
     CDS             complement(26590..27537)
                     /gene="arcC"
                     /locus_tag="ACG8M1_001626"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFQ0422342.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27652..28671)
                     /gene="argF"
                     /locus_tag="ACG8M1_001627"
     CDS             complement(27652..28671)
                     /gene="argF"
                     /locus_tag="ACG8M1_001627"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFQ0422343.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28762..29991)
                     /gene="arcA"
                     /locus_tag="ACG8M1_001628"
     CDS             complement(28762..29991)
                     /gene="arcA"
                     /locus_tag="ACG8M1_001628"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFQ0422344.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         8078 a         6486 c         5365 g        10277 t
ORIGIN      
        1 tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct agaaaatcac
       61 taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag ttttgtctca
      121 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
      181 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      241 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      301 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      361 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      421 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      481 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      541 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      601 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      661 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      721 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      781 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      841 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      901 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      961 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
     1021 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
     1081 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1141 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1201 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1261 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1321 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1381 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1441 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1501 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1561 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1621 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1681 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1741 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1801 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1861 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1921 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1981 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     2041 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     2101 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2161 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2221 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2281 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2341 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2401 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2461 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2521 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2581 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2641 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2701 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2761 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2821 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2881 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2941 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     3001 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     3061 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3121 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3181 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3241 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3301 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3361 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3421 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3481 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3541 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3601 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3661 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3721 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3781 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3841 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3901 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3961 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     4021 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     4081 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4141 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4201 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4261 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4321 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4381 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4441 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4501 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4561 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4621 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4681 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4741 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4801 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4861 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4921 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4981 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     5041 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     5101 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5161 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5221 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5281 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5341 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5401 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5461 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5521 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5581 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5641 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5701 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5761 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5821 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5881 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5941 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     6001 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     6061 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6121 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6181 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6241 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6301 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6361 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6421 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6481 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6541 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6601 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6661 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6721 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6781 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6841 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6901 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6961 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     7021 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     7081 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7141 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7201 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7261 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7321 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7381 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7441 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7501 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7561 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7621 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7681 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7741 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7801 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7861 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7921 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7981 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     8041 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     8101 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8161 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8221 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8281 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8341 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8401 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8461 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8521 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8581 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8641 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8701 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8761 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8821 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8881 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8941 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     9001 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     9061 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9121 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9181 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9241 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9301 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9361 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9421 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9481 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9541 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9601 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9661 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9721 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9781 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9841 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9901 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9961 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
    10021 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
    10081 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10141 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10201 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10261 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10321 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10381 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10441 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10501 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10561 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10621 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10681 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10741 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10801 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10861 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10921 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10981 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    11041 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    11101 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11161 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11221 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11281 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11341 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11401 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11461 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11521 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11581 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11641 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11701 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11761 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11821 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11881 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11941 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    12001 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    12061 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12121 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12181 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12241 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12301 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12361 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12421 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12481 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12541 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12601 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12661 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12721 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12781 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12841 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12901 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12961 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    13021 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    13081 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13141 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13201 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13261 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13321 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13381 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13441 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13501 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13561 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13621 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13681 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13741 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13801 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13861 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13921 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13981 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    14041 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    14101 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14161 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14221 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14281 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14341 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14401 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14461 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14521 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14581 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14641 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14701 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14761 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14821 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14881 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14941 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    15001 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    15061 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15121 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15181 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15241 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15301 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15361 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15421 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15481 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15541 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15601 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15661 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15721 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15781 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15841 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15901 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15961 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    16021 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    16081 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16141 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16201 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16261 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16321 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16381 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16441 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16501 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16561 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16621 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16681 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16741 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16801 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16861 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16921 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16981 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    17041 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    17101 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17161 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17221 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17281 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17341 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17401 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17461 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17521 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17581 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17641 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17701 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17761 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17821 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17881 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17941 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    18001 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    18061 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18121 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18181 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18241 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18301 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18361 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18421 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18481 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18541 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18601 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18661 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18721 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18781 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18841 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18901 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18961 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    19021 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    19081 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19141 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19201 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19261 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19321 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19381 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19441 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19501 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19561 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19621 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19681 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19741 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19801 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19861 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19921 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19981 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    20041 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    20101 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20161 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20221 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20281 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20341 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20401 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20461 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20521 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20581 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20641 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20701 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20761 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20821 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20881 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20941 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    21001 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    21061 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21121 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21181 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21241 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21301 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21361 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21421 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21481 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21541 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21601 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21661 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21721 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21781 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21841 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21901 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21961 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    22021 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    22081 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22141 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22201 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22261 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22321 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22381 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22441 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22501 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22561 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22621 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22681 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22741 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22801 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22861 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22921 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22981 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    23041 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    23101 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23161 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23221 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23281 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23341 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23401 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23461 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23521 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23581 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23641 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23701 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23761 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23821 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23881 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23941 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    24001 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    24061 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24121 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24181 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24241 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24301 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24361 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24421 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24481 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24541 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24601 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24661 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24721 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24781 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24841 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24901 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24961 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    25021 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    25081 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25141 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25201 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25261 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25321 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25381 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25441 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25501 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25561 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25621 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25681 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25741 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25801 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25861 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25921 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25981 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    26041 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    26101 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26161 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26221 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26281 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26341 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26401 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26461 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26521 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26581 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26641 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26701 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26761 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26821 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26881 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26941 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    27001 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    27061 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27121 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27181 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27241 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27301 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27361 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27421 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27481 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27541 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27601 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27661 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27721 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27781 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27841 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27901 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27961 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    28021 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    28081 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28141 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28201 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28261 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28321 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28381 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28441 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28501 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28561 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28621 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28681 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28741 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28801 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28861 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28921 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28981 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    29041 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    29101 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29161 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29221 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29281 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29341 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29401 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29461 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29521 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29581 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29641 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29701 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29761 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29821 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29881 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29941 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    30001 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    30061 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30121 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30181 tttattcatt gaaaaaaatt ttttga
//
LOCUS       DAZKNV010000033        28602 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000033 DAZKNV010000000
VERSION     DAZKNV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.033"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            236..1876
                     /locus_tag="ACG8M1_001629"
     CDS             236..1876
                     /locus_tag="ACG8M1_001629"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFQ0422345.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2030..3352
                     /locus_tag="ACG8M1_001630"
     CDS             2030..3352
                     /locus_tag="ACG8M1_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFQ0422346.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3414..3845)
                     /locus_tag="ACG8M1_001631"
     CDS             complement(3414..3845)
                     /locus_tag="ACG8M1_001631"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422347.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3909..4745)
                     /locus_tag="ACG8M1_001632"
     CDS             complement(3909..4745)
                     /locus_tag="ACG8M1_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFQ0422348.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4935..5237)
                     /locus_tag="ACG8M1_001633"
     CDS             complement(4935..5237)
                     /locus_tag="ACG8M1_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFQ0422349.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5263..5694)
                     /gene="ruvX"
                     /locus_tag="ACG8M1_001634"
     CDS             complement(5263..5694)
                     /gene="ruvX"
                     /locus_tag="ACG8M1_001634"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFQ0422350.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5691..5957)
                     /locus_tag="ACG8M1_001635"
     CDS             complement(5691..5957)
                     /locus_tag="ACG8M1_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFQ0422351.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6211..6936)
                     /locus_tag="ACG8M1_001636"
     CDS             complement(6211..6936)
                     /locus_tag="ACG8M1_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFQ0422352.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7302..7372)
                     /locus_tag="ACG8M1_001637"
     tRNA            complement(7302..7372)
                     /locus_tag="ACG8M1_001637"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7338..7340),aa:Gly,seq:ccc)
     gene            7489..8241
                     /locus_tag="ACG8M1_001638"
     CDS             7489..8241
                     /locus_tag="ACG8M1_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFQ0422353.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8257..8736
                     /locus_tag="ACG8M1_001639"
     CDS             8257..8736
                     /locus_tag="ACG8M1_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFQ0422354.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8987..10567)
                     /locus_tag="ACG8M1_001640"
     CDS             complement(8987..10567)
                     /locus_tag="ACG8M1_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFQ0422355.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10560..11303)
                     /locus_tag="ACG8M1_001641"
     CDS             complement(10560..11303)
                     /locus_tag="ACG8M1_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422356.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11479..12255)
                     /locus_tag="ACG8M1_001642"
     CDS             complement(11479..12255)
                     /locus_tag="ACG8M1_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0422357.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12503..13339)
                     /locus_tag="ACG8M1_001643"
     CDS             complement(12503..13339)
                     /locus_tag="ACG8M1_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFQ0422358.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13350..14279)
                     /locus_tag="ACG8M1_001644"
     CDS             complement(13350..14279)
                     /locus_tag="ACG8M1_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFQ0422359.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14471..14824
                     /locus_tag="ACG8M1_001645"
     CDS             14471..14824
                     /locus_tag="ACG8M1_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFQ0422360.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14898..15554)
                     /locus_tag="ACG8M1_001646"
     CDS             complement(14898..15554)
                     /locus_tag="ACG8M1_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFQ0422361.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15780..17714
                     /locus_tag="ACG8M1_001647"
     CDS             15780..17714
                     /locus_tag="ACG8M1_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0422362.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17800..19023)
                     /locus_tag="ACG8M1_001648"
     CDS             complement(17800..19023)
                     /locus_tag="ACG8M1_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0422363.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19017..20888)
                     /locus_tag="ACG8M1_001649"
     CDS             complement(19017..20888)
                     /locus_tag="ACG8M1_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFQ0422364.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(20909..22027)
                     /locus_tag="ACG8M1_001650"
     CDS             complement(20909..22027)
                     /locus_tag="ACG8M1_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0422365.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22110..22943)
                     /locus_tag="ACG8M1_001651"
     CDS             complement(22110..22943)
                     /locus_tag="ACG8M1_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422366.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22936..23853)
                     /locus_tag="ACG8M1_001652"
     CDS             complement(22936..23853)
                     /locus_tag="ACG8M1_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422367.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24080..25204)
                     /locus_tag="ACG8M1_001653"
     CDS             complement(24080..25204)
                     /locus_tag="ACG8M1_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0422368.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25387..26295
                     /locus_tag="ACG8M1_001654"
     CDS             25387..26295
                     /locus_tag="ACG8M1_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0422369.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26436..28049
                     /locus_tag="ACG8M1_001655"
     CDS             26436..28049
                     /locus_tag="ACG8M1_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0422370.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
BASE COUNT         8893 a         5621 c         4868 g         9220 t
ORIGIN      
        1 tctatttatc tatctaacat atcctttatt cttctacttt tctttcttta gcatataaga
       61 gatacgcata gtaatcaagc aaggattgtt gatataaaaa gaacaaatac cgctattttg
      121 atttcttttg actctattac tcatataaat aaaatttatt atacctgctc tttttgacta
      181 tatcctcatc tgactcctat acttcgtttg tattaaaact taggaggaat cattcatgct
      241 tacagggcta aacttattaa ataatccttt tctaaataaa ggaacagctt ttacaaaaga
      301 agaacgggca aaatacggaa tcactggtat gcttccaagt actgtccaaa cattggaaca
      361 acaatctgtc caagcttacg gtcaatactt aagcaaacag accgatttgg aaaaacgtat
      421 cttcttaatg aatctattca atacgaaccg gacattgttt tataaattga tgggcgaaca
      481 tttagttgaa ttcatgcctg tcgtttatga tcctgtcgtt gcggattcaa tcgaacaata
      541 caacgaaatt ttcttgaaac cacaagatgc tgtatttctt tcaatcgacg aaccagaaaa
      601 tatcaaagca agtttgaaaa acgcagcaga tggacgcgac attcgtttga tcgttgtgac
      661 agatgcagaa ggaatcttag gtatgggtga ctggggtgtg aacggtgttg acatcgctat
      721 cggtaaattg atggtctaca ctgccgcggc tggtatcaat cctgcacaag tcttgcctgt
      781 atcaatcgac gctggtacta ataacgaaga attattgaat aatccattat acttagggaa
      841 tcgtcatgct cgtgtagaag gcgaaactta ctacgaattc attgatcaat tcgttcaatc
      901 agctactgaa ttattcccag aattgttatt acattgggaa gattttggac gaggaaatgc
      961 tgcaacgatc ttagaaaaat acgaagataa aatcactact ttcaatgatg atatccaagg
     1021 cacaggaatc gttgtactag ctggtgtatt aggtggattg aatatatcag gtgagcaatt
     1081 gaaagatcaa acgatcttga catttggtgc tggtactgct ggtgtaggta tcgcaaacat
     1141 ccttttagat gaaatgatcc gtcaaggtgt acctgaagaa gaagcacgcc aacatttcta
     1201 tcaagtagat aaacagggtt tattgtttga agatacaaaa ggattgactc ctggtcaaat
     1261 cccattcgct cgtaaacgct cagaattcac taatgctgat gaattgacaa acttagaagc
     1321 agttgtaaaa gcaatccatc caacgatcat gatcggtact tctacccaac ctggagcatt
     1381 cactgaagaa atcgtgaaag aaatggcggc tcatacccca cgtccaatca tcatgccttt
     1441 gtctaatcca acaaaattgg cagaagcaaa agcaaaagat ttgattgaat ggacggacgg
     1501 aaaagcttta gttggaacag gtatccctgc tgctgatgtg gaatataacg gtgtaactta
     1561 ccaaatcggt caagcaaata atgcgttgat gtacccaggt ttagggcttg gtttgattgc
     1621 ttcaacagct acacgagtaa atgctgaaat catttctcaa gctagtcgag cattaggcgg
     1681 aatcgttgat gtaacaaaac caggagcagc tatcttgcct ccagtagcaa aaatcactga
     1741 attctctcaa acgattgctg aaactgtcgc aaaatcagtt gttgcacaaa aattgaatcg
     1801 tgaagaaatc acggatatca aagaagctgt tgaatctgct aaatgggttc ctgaatataa
     1861 atctttagaa gattaagatt gttatagtaa aagaacatac agaaactttg tatgacgtct
     1921 aaaaagaaaa aagcgactgc ggcaaaacag cagccagcca actactgctc ttttgccgct
     1981 tctctttggc ttttttcata cgatacagaa taagaaagga tctgtaaaaa tggcacaaaa
     2041 aacaacaacc gcaactgcag ttgaggaaaa gaaaaaagaa gggttttggt caacaaaaat
     2101 taccggcgta agtttgcccc tttatttgat catggtcctt gtcctgatca ttgcaatggc
     2161 tttaggaaaa ttaccgacga atatgattgg cccaatcgct gttttggtca ttttcggtaa
     2221 tttatttcat tttatcggaa caaaaatccc tatagtcaaa agttatttag gtggtggctc
     2281 cgtttttgcg atctttgcct ctgccgcgat tgctacattt gggatcttac ctgagtatgt
     2341 agtaaaatcc acagaaaact ttgtcagcaa tatgggcttt ttagactttt atattgctgc
     2401 cttgattact ggtagcatcc ttggtatgaa ccgtaatcta ttgatgaaag cttctgttcg
     2461 ttttattccc gttgcactta tttcaatggt cgtctccttt tttgccgtag gactcgtagg
     2521 tatgcttatc ggaaatggtt ttgcaaattc cgttttatat atctcattgc ccgcaatggc
     2581 tggtggtgtt ggagccggag ctgtaccttt atcaacgatt tatgcaaatg ttttaggtac
     2641 ggacgcttct tctatcattt cccgcctgat tcctgcgaca gcaatgacaa atgtcctagc
     2701 tatcattggt gcagcgttag ttgctcgtgc gggacaatca atgccaaaat tcaacggtaa
     2761 tggtaaatta atggaaaaag gcgaccttgg cgatggaaaa cctagaaatg taaaaccttc
     2821 cattccacaa ttaggtgtcg gtttgatggt atcattgact ttcttcatct taggacaaat
     2881 ctgtaactat tttgttccta aagtccatgc ttacgcattc atgatcatta tcgttgttat
     2941 ctgtaaaatc gcaaacctat taccagaata ttacgaagat gcagctatca tgttcaacaa
     3001 cttgattgtc aaaaacttga cagcagctgt tcttgccggt atcggtattg cgttattgaa
     3061 tctaaatgta ttggcttctg ctttgacatg gcaatttgtt gtcttatgtt tgacaagtgt
     3121 tatcgcgatt tcagtagttt caggatttgt cggtcgtttg tttggtttat atccaatcga
     3181 atcaactatt actgctggct tatgcaacaa ctcgatgggt ggtacaggaa atgtagctgt
     3241 cttatctgca gctaatcgga tggaacttat tgcttttgct caaatgggca atcggcttgg
     3301 tggtgccatc gttttgatca tctcaggttt cttgatgcaa ttactttctt agtcaaaaaa
     3361 aatacctgat catcaagtat cggcttgatg accaggtatt ttttgataaa aatttacagg
     3421 attttcaaaa atcttttttg cattttatcg gaatgataac cgatgcgttc ataaaatcgg
     3481 tgtgcttcta ctctgtattc tgcagaatta agtcttattg ctgatattcc tcgtcttttc
     3541 gcttcttcta cgccagtcat caaggccttt ccgattcctc ttttttcagc atgtttagac
     3601 acagcaagtg ccataatatt gaacatcgga tcgctgaaaa tcgattcata ggactccgct
     3661 tgtacatagc cagctgcttt tttagaagta ggatcttcat agaccaagaa aaaatttttt
     3721 tctggctcct tcaacagttt cttcatttgt ctcaccgtaa cggttaatgg tacatcatat
     3781 cctaattgtt ccgcattgat ttctcgtagt gcttctgcat ctcctaaacg catttcccgc
     3841 aacatccaaa tcaccagcca atttttattt ttttaaatga atttttttat cacagtatac
     3901 tccttttttc acttaaaaaa agacttttca gtgattttga cttgcttgaa tccagatcct
     3961 tctaatgttt gcaagatgac gaaagcattg taaagattga tcaaaagaac cacgatgaca
     4021 atcgcttgaa aaataaaggt cacttttttt ggagacaaaa ccctgctaaa tcttgctccc
     4081 cacaaacctc caataacagc agcggggata acataaaaca acatagataa atcaaagcgc
     4141 ataaagctac ttgttaaagc aatcgttacc aattttgcca gttgagaaaa gaaaatcgta
     4201 gatagagaat atagtgttgc ttcttttatt ggcaatgcaa acatcagcat caacaaagaa
     4261 acattgactg gtccaccacc aatacctaaa aaactagcta aaaagcccag aaccccccca
     4321 catataaggt accaagtcca tgacgtcaaa tgaaattttg gctgatgatg cttggtgtag
     4381 aagaacgcaa aaaccaaggt caataccgtc aaaaaaattt ggatcagctg cacatgcttc
     4441 tcgttttcaa ataactgtaa aaaaacttcg aatacaatgt tgccgactac tcctccaaca
     4501 acagctccac tagataccca accgacaatc tgccaattca gtgatttccc gcttgatact
     4561 tgtcgcacag tcgaaacaat ggacatcgtg aataccgcaa ctgttgagta aaaagaaatc
     4621 cctgcaacag aatgggcgcc gataagatca agaatcggtt tgatcaacac gcctccaccc
     4681 atcccggaaa tagcgccaac tgtgttcgcc agaacgatca ccacaaaata aatcagacca
     4741 atcatcttgt atttcctttc tcttgtttat atcttttagc gattgttact cttttctttt
     4801 attatacagt aaaagaaaca aacgaggctt cgaaagcttt tctacttttt aaggaaattt
     4861 agtgctaaac gaaaaaaccg ggctctactt ttcagagagt ccagcttttc ttacacctta
     4921 tcgattcttt tgttctattc ttcttccgcc atgaatgtat tgaatacttc ttcgatcata
     4981 tcccattctg cgtctgtttc gatttgttct aactcgcctt ctgttccatc ttcgttttcg
     5041 atgtatgcat aagcttgtaa ttctacatct tcatcttctg aaacaccagc tggatataaa
     5101 agaacatagt tacgtccaaa ttcttcttgt ccgtcaactg ttagcaagat ttcgtataat
     5161 gtttcatttc cttggtcatc caccaatgtg atgtgttcgt gtccttcgtg ttcgtgggaa
     5221 tggttatgtt ctgtcataag attacctctt ttctttttat tattaaaata attgcttacc
     5281 tgagccgtct aaataatttt gtaaaatcat cacagctgct aatttatcga tgactttttt
     5341 tcgtttcgct cttgaagtat ttgcctgctc tactagcata cgttctgcct gaacagtggt
     5401 tagtcgttca tcttgataat caaccggcaa ggagaatagt tctttgatct tctctccata
     5461 tgacatggaa gcttctgccc ttggtccgat ggaattgttc atattcttag gtaatccaac
     5521 tacaaaacgg tctacttcgt actgcgccac taattccttc aaccgatcaa aaccaaactc
     5581 ttcttctgcc tcattgattc gaatgatttc tactccttga gctgtccagc caaagggatc
     5641 gctcacagca acgcctactg tcttagaacc gacatccaag cccattactc tcataaattc
     5701 actccatgat ttgagaggta gtctttgaca attacttcca tgatttcatc gcgttcgtga
     5761 cggcgaatca aatttcgtgc atcacgataa cgaggaatgt aggccgggtc tccagaaagc
     5821 aagtagccga caatctgatt gattggattg tagccttttt cttccaaagc ccgataaaca
     5881 atcgctaatg tttcgctcac ttcttttttg cgactatcgt caaaaccaaa acgtacggtt
     5941 tcatctgtaa aacccatgat tctacacctc tttcccgcaa ggtaattcca gcttaccttc
     6001 tacaccctta ttttactcga agaaagggaa aactacaaac aaatattcca aacttctgaa
     6061 taaattaaga aacacgattt gtctgatttt tccttttttc tgtggctttt tcaaaagccc
     6121 tctttccata aagtatacgc tatatttctt tgaaagtatg tttttacaca attttttcat
     6181 aaagttcata aaaaattcga attgctgcta ctaatttttc gttttcgttg cttgccctgt
     6241 ctcataattg atggtgtagc catcttgaac attgtagata aagacattga attcaatttt
     6301 tttgtcttca atgctttctg cttccaactg cacacctctt gctaccagtt catttccctc
     6361 gaaatgagga gtgacacgat agcgtacatg atgatttgtt tccttgatat atgccgcaat
     6421 atcattttcg tgggcaagca tgtacggagc attcaacgaa cgtgtccctg tcattaagtt
     6481 tttaatgtta ttattttgac cagtcaactg gaaaccaatc aaatggctgc ggttgtataa
     6541 ccattgtccg tcacttaatt tcttttgttt ccaacctgtc ggatcaatat acaaaggttc
     6601 tctcttttca gtaggaaaca agtcttttcc caacatcgca ttggcttgtc ctactctgtt
     6661 caatttgtct atatttgaat agctttccca tgtccctttg gaaagactaa gatcctcttt
     6721 tgtaaactcc ggctgattcc cattgatttc tatttcttga tgttttccat catattctgg
     6781 cacatccgct acttgagaag cttgcggtgt ggaatcaaaa atggttgtaa tttgttggaa
     6841 gatatctgaa tctttttgtg tggtggaaat accgagtgcc cctgcaatca cagcagcgac
     6901 gatccccacg atcgccttgg ttgttttttt gctcatttct ttactccttt actaacagtt
     6961 ccctaaatct taacatatgt tcccctataa ataaatactg gaaagaaata gaaacagtaa
     7021 aaaaataaaa ccagttttta gacggcttaa gaatacaaaa aaagagacgg attcatcgtc
     7081 tctactcaat cacaaaacac tatttacaag gtatttatta tcattcaaaa aatttttctt
     7141 aatactcaaa actaaacggc ttctgtacga cctcttggta aacagtgttc aaaagcttgc
     7201 atctgcggta ataagtccaa ccaagtcaaa aacataagaa gcttttttgc ttgactattc
     7261 ttattacttg atgcagggca gctttttcac agcctctttt aagcgggtga cgggaatcga
     7321 acccgcgaca tcagcttggg aagctgggat tttaccacta aactacaccc gcgatacaaa
     7381 aacagtatac gcctctttca ctccttcctc aagttttttt attctttacg cttccgatat
     7441 gttttgtagt aaaataaaac taatcaatca attattggag aagatgctat gacgggaaaa
     7501 gaattagatc tgttgctgga cacttgttta ctcgctggga aaatcatgat ggaaagcaat
     7561 gcggagatgt atcgggtaga agatacgatg agtcgaattg ctttagcttc tggaaatttc
     7621 cgtttggtca gctatgtcac tcaaaccggt ctctttattg gtcttgatcg tacctcgacc
     7681 atccgaatgg aacaaattac caaccgttcg attaatttag aaaaagtagt aaaagtaaat
     7741 gatctttcac gtaaatatgt tgcttcagag ctaacattag aagaacttta ctgcgaactg
     7801 caagcaatcg accgagaccg ttctttcttt cctgtctggt tgcaaatcgt tagcgcggca
     7861 gtgatcagtg gaacaattat ggtgttattt ggcggaaaga tgaccgattt acctgtgact
     7921 ttagtcattg gaggattggg atacgcagct tatctatata gtttgaaatt ttttagaatc
     7981 aaatttttat cggaattttt atcttcttta ttgattggca tagccgctat ctacagcgta
     8041 cgttttggct taggaagcaa tcaggatcta atcattatcg gatgtgtgat gcctttagtt
     8101 cctggagttc aaattacgaa cgctatccgt gatttgctag ctggacatta tgtctcagga
     8161 gtttctcgcg gaacagaagc gatgatgact gctacgatga tcggttttgc gattgctttt
     8221 attttccagc ttttttatta ggaaaggaac acaagtatgg ggacgatatt tattcagttt
     8281 tcttttagtt ttttagcgac tgcggcattt gccgttatta caaatgtacc taggcgttca
     8341 ttgatttgtt gtggtctttc tggtgctttt ggctggatga tctactggat ctgtgttcaa
     8401 ataggcggat ctgctgcttt tggttcattg cttggttctt taggagtagc attcatcagc
     8461 gatcttttct ctaaacgttt gaaaatgccc gtaacgattt tcaatattcc cgggatggtt
     8521 cctctagtcc ctggtggttt agcttatcaa gcggttcgaa atctcgttac tgaatcctat
     8581 cgagaagcgg ctcattatgc ggtccaagca attatgattg ctggagcaat cgctttaggt
     8641 cttgtattat cagaagtctt taaccataac atccgtaatt tcaaagtaaa gcgtgacgca
     8701 atcatgatga aacgaaaaaa acggcttttt aaataaacga agtgtaacaa agaaaaggtt
     8761 gtgaaagaga cgttcagcct tgagcgatga caaaatatct cacaaacatt gcgacaagta
     8821 accgcaggag caataagaag taattatgag tattaaaaaa agttttgtaa aaatagcttc
     8881 tcacattttt acataaaatt gacttaatac tgagaaactg acttttgaac accctctatc
     8941 tgtaaaaaag gggctgcgac atgatttttg tcacggcccc tcttctttat tcaaattttt
     9001 tccaaaacgt tcgttgataa taaacgatcc atagagcgga aagtattaga actaaaccga
     9061 tcacaggaat attcactaac caaaatggat aaaacaaagc caacattccg tataagacga
     9121 taagaataat actgatgatc aatgaaccca tcatagttgc gactaaaccc aaacttcctg
     9181 aacctctgtt aaataattgg ttaatattgg tccagttcag cagcagcaac cgataatctc
     9241 tagcgaaata acgtagtgac aataagtagc agccgaataa agaaccaaat agcaagctag
     9301 ggataaaaaa caaaggcagc tgaaaagaca gtccgcttaa taatgcgatc ccaccagtta
     9361 aaaaactctg caatatccat ccgaatctga acttttcttt taaatattgg ttcatagaga
     9421 ttggcaaaga acggataaac agaaaatttt cttgatccaa agaaataaga ttgctgataa
     9481 aagaagtctg attaactgtt aagaaagcca atgcgatccc taccaggaaa acaacaccga
     9541 ttaacttatt atctaaatca gttaatttta tttcgcctcc tagggcaaaa gcaagaataa
     9601 aaatgattgg agttaacaag gaagaagaaa gaacttgcat aatcaaatta ggttctttta
     9661 ctaattgagc attgtaacta aataaaagct gatgcacatt ttggttcttt ttatgggttc
     9721 tttttatttt gaactcactg tttgaatcag tcagttgctc tgtaagcttt ggtactatca
     9781 gctgttttac agcaaggaaa aatcccagag ccgtgatagc tagtattccc caacccaata
     9841 aaccttgttg agaaagtggc tgactggcag catcatagaa tggcaataat atcgaaatcg
     9901 gatgccgatc tgttaactca ttttcaatag tccccgtttg atgattcatc cacatgattc
     9961 cagcaaatgc gatcagcatc gagctgccaa gcaagatact agaaactgtt tttctatgtt
    10021 ttttaaacac tgctgttcga gccaaaccaa aaacaatcaa actagccaga caaaaaagaa
    10081 taatcaaaaa tagagaaaac aaaaggattg agataatgat agtaagcaaa atccctagat
    10141 cagctcgcca tccggttaaa ataaacatga ctagaagcgg aaaaacaaaa ggaatgatgg
    10201 tcaaagcaac taccaaaatc tttgctgaaa aaacctgttc ttgtccaaaa ggcagaggca
    10261 aaaatacttg caggtcattt ccttcaaaaa agatattata aatgactgat atactttgag
    10321 ttaaacctaa cataccaaaa agtgccacgt aataagtaaa gaaacctggc aatttaacaa
    10381 agttcatagc aaacatagca aatccgtaaa tcagtaaaaa aatcagccct gaaaaaagat
    10441 tttgagacaa aagatagata gttaatcgct ttcccttttt tcctttctct cttgctttat
    10501 tcgtgagctg tggattaaca tataaaagat taactcgaat taattctaat aattgtcgct
    10561 tatacatacg gtccatctcc tgtcgcttgc cttccagcca ttttcaaata aatcttttct
    10621 agcgtttcat caggtgagcc attcaataat tcactaactg ccccctgata aatcaattca
    10681 cctttcttca aaatagccag tttatcgcat aactgttgtg cggtatccaa tacatgtgta
    10741 gaaaaaatga ctgtttttcc ttttgcggca tgagccttca tcatttcttt caaatcaaat
    10801 gctgcttgag gatcaagtcc ttgcaaaggt tcatccaata cccaaatatc tggatctggc
    10861 agcaacgtgc cgatcaaaat cgttttttga cgcattccat gtgaaaaact tgcgattgtt
    10921 tcattttgat gactatacat atcaaaaagc gctgtcaatt ctgctaaacg cttttctttt
    10981 ttttgtgtgt ctaattcata ggcagctgaa atcaagtccc aatattctcc agccgtcaat
    11041 tgtaaaaaaa tatctgggga atcaggcaca taaccgattt tttgtttgat actcaatcga
    11101 ttttccgtca atttcattcc atctactaaa atcgttcccg atgatggttc aataatacta
    11161 actaaacttt taatcgtagt tgattttccg gcaccattat gtcctaaaaa tccaaaaatt
    11221 tccccttgtc ttatcgagag agacaagtct tttaatgctt gttttttccc gtaactttta
    11281 cttacattga tgaattcaat catttctgta ctccttttgt ttgttattac tttttattgt
    11341 acccttcgtt attggtggag taaatgtcaa aaagagtgca taacaaaaaa ggatagaaac
    11401 gactaggctg ctacttgggt tgttctcttc tacaggaaaa cactcttcta acaggtaaga
    11461 tatgagtctt tgttttcttt aaaatgattc attttctatc ttttcttgca taaaattctt
    11521 tagtttatca atacttctct ttcccatctc tagttgttct ccatttgcaa atgttactat
    11581 ttcgtttact ctgctaatag atgtaatgtt ttcagtatta atgatataag cttttaaatc
    11641 tttacataaa tactcatatt cgagtgattt tttatatttt ttaattgtgc cgtttacgag
    11701 aatctcttca tctttcaata ctaggcctat tttattttta taacctggca tgctcattag
    11761 ataaaggatt tcatcgtaat ggatatagtg atcgctatta ccataacgga cagttgtcca
    11821 cctttttttc gtagcatgtt gaacaggata gttttctttt tctttcaata agtaactttg
    11881 gatgcttttt ttattttttt cataagtgaa ttcttttatc aaataaccac taggcgtaat
    11941 ctttcgatta ataacagtta ttgctttatt cggatgagac gttagataaa caattttaca
    12001 cttttcattc ttttctctaa gcatttcgcc tagttcgata ccgctataat aggcgttcaa
    12061 atcgatgtct aggaaaaaaa tatctgagga atagatttca ttatttttaa tgaattcaac
    12121 aaattgtata acgttcaatc cctgaacgat ctcaaatttc caaggactta ataaaattct
    12181 ggattcttcc aaaatttcta ctagcatttt ttcaaaaacc aaactatcat ccaaaataaa
    12241 tatacgcgtt accataaaaa gtacctccac tcgatatttt actatcaaaa tcatttcata
    12301 caacttttca acatacatgt taggaataaa ttgtaattct cttcacaatc ttttccaaca
    12361 cctttgaaac cgatatcaaa tactttcagg atgctgcttc taaaataaat atcaaacaaa
    12421 tgaatacatc atgcaaaaaa agccagacaa ccgacgtcct tgcgtgtcag ctgtctgagc
    12481 tatgtttatt tattttgttc ttttaaaaag aacgatacac atactgattt ttcggagcag
    12541 agactttctc agcgtttgta acaactacag atgggatttc acgcttgaat ggttgataat
    12601 agtctgattg gatggttcct tctattttat accattcatc atttttaacc gttactcctt
    12661 ccggcatatg cgtcaacaaa ccaaagactc ctgaatctgc cacacaatgg ataatgccga
    12721 atcggaacaa gaagatatct gtattgctat cgttcggtgt ttggtaaaca aatccttcat
    12781 agctgatttt tttgccaatg aattcgctag ggtaattata aattagctcc ataacttcta
    12841 aatagttttc atctgtgatc ttgatagttt gcttatcccc atacttttct ttcaactcat
    12901 tcatttggtc taagtagtct gatttgttga aataaatact ggtatccggc tttaagtatt
    12961 gtgtctgcat ctccggatcc cctactgatt ctttacttac tgggaaatta aatcctttgg
    13021 cttctacgat cgtagtgtcg agactaactg ttggaaacaa cgtccccacg attactggca
    13081 aagctagcag tacataagcg attccacgtt gataaggttt tgacaaccca tggtcatgat
    13141 cgtgctcgtg tgccttttct tctgcttttc cgtttttgac ccacaaatac agctgaacta
    13201 aagccaaaag agcagataaa atcattgaaa gaatagctaa gtagcgataa tggacattga
    13261 tatattgatc gagtttgcca gaaacttgca agtacatcat caattcgaaa tacccagata
    13321 aaatcaaaaa ccgcagcata ttttccctcc taaataaata atgtgaatcc aataacgcta
    13381 agggcaatca gtccgatcag cgataaaata aagcgtcctg taaaatatcg tttcatcatc
    13441 agtagatttt tgatatcgac cattgggcca aagaccaaaa aggcagctac aggtgctgtg
    13501 ccgaacagac ttaacaaaga agatcctata aacgcatctg cttctgagca aagagacatc
    13561 gtaaaggcca ataacagcat gatgataatg gctaaaatct ttgttgagcc gagcgttagc
    13621 ataattctag ttggtaaata agtctgcatc gcagctgcga ttaatccgcc aatgatcaaa
    13681 taacgacctg tatcaaaaaa ttcgtcgatt gaatgtgtca acacatgccc agtttgatgg
    13741 atcagctgat tttttggttc attcttctca ctttgttctt cttcatggac atgatgatgg
    13801 tgattttctg ctactttaga cgtgattttt tctttcaata cagcgtcttt ttgaaaatag
    13861 gcaagccaga caccaatcac aagggcaaca aaaaagctgc ctatcacccg ccagcttgcc
    13921 atctgccaag aattgccaaa tgcgataaaa gtggaaaaaa tcacgattgg attgatgatc
    13981 ggagcagtca gcataaaagc aaacgctgtg tgaactggta cgcctttttt aacaaattga
    14041 tgaacgatcg gtacgatgcc gcattcacat gaaggaaaga aaaatcctaa gatcgaacca
    14101 gtaaaaatag agaagatacg attttcagga agccatctct tcacacgttc tggggtcaaa
    14161 aatacttgta aggcgcctga gataagacag cctaataata cgaaaggtaa tgcttcaata
    14221 acgatcgata agaaaatcgt actcatctgc aaaaccgaat ttggaataaa agaaaacatg
    14281 agtttcctcc tttttatttc tagttcattc gctttgcaaa tatacgcttt tattcaaaaa
    14341 aaacaagttg ctctgtaaat ttttacacaa ctcttatttt ttaccaaagc acttcaattg
    14401 actttttctg ttattcccat taaattaagg tctcatacat atcacttcta tcataaaagg
    14461 gagaataaaa atgaaacaaa ccactaactt gactgaagtt caagacatac tgcaacagtc
    14521 atccgttgcc gtcatttatc tttcgatgcc taattgcagt gtttgtcacg ctgttcgtcc
    14581 acgactagag gaacttctca cacattatga tattccggca cttcatttgg atgcatttga
    14641 aacaccagaa gtagctagta aatttgaagt gctgactgcg ccagttgtcc tgatttttca
    14701 tcaaggaaaa gaagtctttc ggcaagcacg gttcatcgac tttaaaaaaa tccgttatct
    14761 actagatgaa ctgacagcag aagatgattc cctttcttat gaagaaatct tccgaacaaa
    14821 ataatcgttg tccaaacaga aaaaagcgat tgaacaagtg aaagttttgc cttcatttgt
    14881 tcaatcgctt tttattttta ttctgctgta ttttcggaat gcgcatttgc gtcagaatgc
    14941 aagaaataga tcaaggtttg caattcattc gtcaaatcaa cattttggat caatacatct
    15001 gacggagcat tcaatcgagc agcggtaaag ttcaagattc ctttgattcc tgcttccgtt
    15061 aactgattga ctacttcttg tgctctttca gcgggtatcg ttaaaattgc tacttcgatt
    15121 tgttggatct tgatttgttc tgacatatct tccattggat aaacggggat accgtctacg
    15181 atgcgcccaa cgatttcctc attcacatca aaagcacaac tgatacgtat gctattactt
    15241 tgatggaatt tgtattttag taaagcactt cccaagttcc ctacaccgat cagcgcaaca
    15301 tttgtcaatt gatcgtcgtt taatgtcttt gcaaaaaagt gcataagatc ttctacatca
    15361 taaccatacc cacgttttcc taattcgcca aaataagaaa aatctcgacg gatcgttgca
    15421 ctatctactt gaacggcttc acttaattca gttgaagaca cttttttctt tccagcatta
    15481 tttaaaatcc ttaaatagcg ataatacaaa ggcagtcttt tagctgtcgc ctttggaata
    15541 atatgatctt tcacgaaatg acctccacgt attgtctaat tacatctttg atttctccat
    15601 catagcagta tttataggaa aaaatcaatt ccattgctca gatattgtga aattttattc
    15661 tttattcatt tatttatcat ttctgcaaat ctcgcagtat aatggaattt atggtagact
    15721 actaattgaa aaatagtttt ttatttgagg agaattcaca aagtagaaaa gaggattcca
    15781 tgatattatt acaagccaat cagattgctc gccattttgg tgcagaagtc ttatttgaaa
    15841 acatacattt agaaatcagt acaggcgctc gtgtcgcttt agttggcaga aatggcgctg
    15901 gaaaatcgac tttattaaag atcattgctg gaattgaagc acctgatgaa ggaaagatcg
    15961 ctaaaaataa aacagcgact ctcggatacc tcgctcagga cacaggactt gattccaatg
    16021 aaacagtttg gaacgagatg ctgaaagctt ttgaacaagt tagacaaatg gaagagcgga
    16081 tgcgcgagct agagattttc attagcgaag gtacgccaga cacacctgct tatagttctt
    16141 atttaaaaga atacgaccgg ctgcaacacg atttttcaga tcgaaacggc tatggttatg
    16201 aaaatgaaat tcgttccgta ttgcatgggt ttaaattcga ttcttcattt tatgatcaga
    16261 aaatcgatac tttatcaggc ggacagcgca cacgtttagc tttagctcgc atgcttttgc
    16321 aacaccctga cattttgatt ctagacgaac caacgaacca tttagatatc gagacacttt
    16381 cctggcttga gaattatctg caaagctata ctggtgcatt attgattgtt tcccatgacc
    16441 gttatttttt agataaagta gtcaatgaag tctatgaatt aagcagaaga aaaatgcgcc
    16501 attacaaagg taactattcg aaatatctag atttgaaagc agaacagtta gcaagtgaat
    16561 ggaaggctta tgaaaagcag caaacagaaa tccataaatt agaagacttc gttgctcgga
    16621 accttgttcg cgcctctacc acaaaacgag cgcaaagccg cagaaagaca ttagaaaaaa
    16681 tggaccggct ggatcgtcct caaggggatg aaaaacaagc aaactttcta ttcagtatag
    16741 aaaagccttc tggaaatgta gtcttgcaaa tcgaagatgc cgctatcgga tatgataatg
    16801 tcaccttatc tgaaccaatc aatctagata tccgtcgtca agaagcgatt gctctagtag
    16861 gtccgaatgg tatcgggaaa tcgacgttgc tgaaatcaat cattcaccag atccctttta
    16921 tccgtggaaa agaaacgcta gggacaaatg tcaccatcgg ctattacgat caaggtcaag
    16981 ctgatctgca tacaaacaag acgatcctag cagaattgtg ggatgagcat cctaccactc
    17041 cagaaaaaga gatccgaagt gctttaggtg ctttcttatt ttctggcgaa gatgtagaaa
    17101 aaccaatccc tctgctaagt ggcggtgaaa aagcacgggt tgctttagcc aagttagcga
    17161 tgaacaaaga aaattttttg attttggatg aaccaacaaa ccatttagat attgacaaca
    17221 aagaagtatt agaaaatgca ttgatcgatt atgacggcac actgcttttt gtttcccatg
    17281 accgatattt catcaatcgg atcgcgacaa aagtcgtcga actctctgaa aatggcagca
    17341 aagtctatct aggagactat gattattatt tagagaaaaa gcaggaagaa gaagaaatcg
    17401 ccgaattgtt ggcacaagat gagccagaat ctgctcctgc tcccacgaac aaatctgatt
    17461 attaccaaag caaagaacag caaaagctta tccgtagcct tcaacgaaaa attactcagg
    17521 ttgaagaaga aatggcgcgg atcgatgaat ggatcgatca gttggaacaa gaaatggtcg
    17581 cgccagaaaa cctggaagat cacgtaaaac tcaatgagct gaaccaagat ttagaagctg
    17641 ctagacaaga tcaagaaaca aaattgacgg aatgggaaga actaagcttg gaattagaag
    17701 aatatgaaaa ttaacgaaaa aaccaaaaca gaaaccattc atgctgtttt ggtttttctt
    17761 tttttatttt atcaaacaaa aattccatat ttaccttttt caccaataag aagaccaatt
    17821 actagtcatt ctcactaaag cttctaaata atagtaatca ccccaaatac aaggtgtatt
    17881 taccccatta tttttgggct tattataaac agactgtgtt aaaaagccat cttcttcttc
    17941 cgttgtagca tatctttctt tcaattgtcg cataattttc caaacagcag actggtataa
    18001 gttcttttct gttttgtcta atagacctga ttctattaat tctaataatc cacaaaccat
    18061 gatcaccata ctagatgtat ctttttcttc tctgctagaa tcatcaaaga tcaaatccca
    18121 ataacaaatg gtatcttctg gcaaccgatt cataaaataa ttggctaata ttttgcttaa
    18181 atcaaaatat ttttgttctt tcaaataacg ataacttaat gcaaaaccgt aaatccccca
    18241 tgcttggcct ctagcccaac aggaattatc actataacct tgatgcgtac ttccatatct
    18301 tggttttcca tctttgacat ccatataaaa tgtatgataa gttgaaccat cttctcttac
    18361 taaataatct gctgcatttt gaatatgagc ctgagcagct tttttatatt tttgatttcc
    18421 agtttcttca ctcgcccaat acaataatgg aagattcatg caacaatcca tgatcattct
    18481 accttgttgt gaaggatcac taggatctcc ccaagcttgt ataactcctg ccttctccca
    18541 aaaacgctga agtaatgttt ctgcagcatc aattgaagct tccttcattt ttcgatttcc
    18601 cgttatttta taatctgcta cggttgataa agaatacaaa aaaccaagat cgtgatgatt
    18661 agtgataatt tgacagtcaa tcctgtggat aaaatctata tctgcttttt cagctgtttg
    18721 ttgaaataaa ggatcacccg tcttctcaaa taacaaccaa ttaattcctg tccaaaatcc
    18781 ttctgtccaa ccaatattgt ctcttaatgg ataacgtcct tttataggac actcgcttgg
    18841 gaattgatac tgactgttac tgatacgttt gattaacctc tccgtgtgtc tgcgacaacg
    18901 ctcgatctca ttattccatt ctttttccat taattcttta taacattcat ttatccattt
    18961 ttctggatgt attatctctt caaacatcac tttatcaagc atttccccac cagcctttag
    19021 cataatttta gtcttttttt attgttttta ttttggatag ttagcccggt tgtcccatca
    19081 aaatcaattt tgggacgatt gttccatact tctaaactat aatcccgatc ttgatgagca
    19141 accactcctg ttccgagcca atgggttcct tttccaaatg taccctctaa tccaggaata
    19201 aaagtgtttt cccatgtcat caagtttgta ttgggcaaac ccataatagc tgtggatttt
    19261 cgtttaatag tatcgtcact taaacagata atacctgaaa agccagcttc actcacccta
    19321 tagttttcct tgtcttcttc tatgattatt ccttctttct caggagaaca ttcaatagca
    19381 aaccctgtct catatagaac atattctgta tctaattcta ctttgtgtac gcgaatctgc
    19441 cagccttcaa aaggaataag ccaagttctg atttttgcct gtaaagtagg ttcccatgta
    19501 gaggcaagta cctctttctt acatacaatg tctcgtacat tatttcgaac gatgaactgt
    19561 ccataggttt tgatgctctc attcttaaaa ctggtcgtga tatatgtgtc cgctcgctga
    19621 atccctagca ttgaatccat tgccatttct gctttcaatt gattcgctcg cggtatcgaa
    19681 aaaccaaatt gactagaata agcaaatttt aaatattttt cattggtcaa tgtatggaaa
    19741 tttggcccta attgtcccgc attcaaaaaa aatgtatgtc cattatcatg ttgtatgagc
    19801 aaattggctt ctgaaagaag tttagttcct tcacgaatag gcataggcat ttctttagcc
    19861 gtccaatact catggtcttc aggtagcgcc aacaataaaa aaatcttatt cagccataat
    19921 ggagataacg tactattata gggttcagtc aatgtcaatt gagggtaggt ataaccaata
    19981 ttcaggatac ctttttcatc aaatatttct ttttgcatcc accatcttat attccgattg
    20041 actaacccct tgatttcacc taatttaaaa ggcaaaagat cggcccacaa catagctgac
    20101 caaaagcttg aaactgcaaa acgataaatc atgcttcgac caaaaggcac atttgcacca
    20161 tcttccgcaa aaaaatgaat atagtctcta gaaaaatcaa tagctcggtt cttatatatc
    20221 tggctaatgg gcttttctgg ttctagtacg ctataaatca aaccataata atgaaatgca
    20281 aaaggattat aataatcttg gcgacctctt gaactgtctc gataccagcc attttgaaga
    20341 taacaatttt ctatattatc aaatgcttct ttcagtgctg attctttaac tggataacca
    20401 aatttttgga taattgttcc gacaattatc ttaaaaaatt gccaattacc atctgcacat
    20461 tcatattcaa aaatttgcga gaaccaatga ataatctggc ttttttctcc tgtatctaat
    20521 tttttccata ataattgttc atgatgatat aacgctaata acattgcggg catttctacc
    20581 atacgctggt ctctttcatg tatttctccc caataatcgg gatgggaagg atctgttcca
    20641 gcttttattc ctgatagaat taatttcaac catcgttcat ctaattggtc aattgcgggc
    20701 cccgctcccc ataaaacccg agagaatcct tccattcctg caattttatt tccatatcct
    20761 accccttgat gtatataatc aatttgtgcg ccacttgctc gataaaacgg ctggagtggt
    20821 tgatttatct ttttaaataa gtcaaagtaa tcctgtctgg tccttaatag tggtactgga
    20881 tgtttcattg tattttctcc tctttttact accaaatagc taattccgac tgttctaatc
    20941 gaagtaagcc ttcaataaaa aaataatcag aatagatcag tggcacatta taagtcagtt
    21001 ctctatggta tgcttctgct ccgcctccaa tgatcccatc ttcatccata ttccaatttg
    21061 catagtgctt ttctgtcttt tggagtatat tgatagcagc ttcatgatac atttttgatc
    21121 gtacagagga aacatatcct gctaattcca gaagaccgca tgcagcgcat actccagcac
    21181 tggtatcaat attcgaatct tttacagcaa aatcaatgag aggaatataa ccagtttttt
    21241 cgattttctg aataaaattt actgctatct tttctgctat agctagatag tacggatttt
    21301 ttgtgtaacg ataacttaac gcgaatccat ataaagccca tgcatttcct ctgctccaac
    21361 aagaattctc attgtatcct tgcccgccaa gtaaccgaat atatttccct gattctgcat
    21421 caaattctgc gatatgcccg gttgatccat ctttcctcac tagatactta gctgttgtat
    21481 ctgcatgctg ccgagcaatt ttagagaacc tcggatcacc agtttccctc gaagcccaat
    21541 acagtaatgg taaattcatc atactatcaa taatcatcca accaggttta tggtcattcc
    21601 atgctactaa atagttccct gaaatattat agcgtccagc aagtaccgta gctgcatgta
    21661 accctagttg tcgactatgt ttgttttgag actgttgata atgtgcaata gccgatggta
    21721 agaataaaaa acctacatca tgatgaacgt ctgaaaaatg gtacagggca gattctaata
    21781 attgttcttg ttgtattgct gcctctttga acttttctcg ttttgtcttg tgaaagagct
    21841 gccataaaat accactccaa aaaccattgg tccaccagtc gattcctctg tcctttatta
    21901 cgtctgtata ttttccgttg taagaaatat atggaatttt attccccatt ctgtctaatt
    21961 ccgcatctat cttttcagaa gctacattca aaatttttct tgaccattcc ttcgtctgtt
    22021 cattcatgga tatcccgcca ttcttttaat ttttatgaat gtggagttgc tcctagaacg
    22081 aactagatgg ttaacattcg ttattttttt tacttatttg cagctccaat gtcattctcc
    22141 ttaaatttag actgcgccca cacataaatc aagaccattg ggatcactga agttgctaaa
    22201 attagcataa ttgcgccata attaattggc tcacctgtac tagaaaccgt catatttttg
    22261 ataattaagg gaaccgtata tttatcttta tctgaaagca tgactaatgg aaatagatat
    22321 tgattccaac ttcccataaa gataagtaaa ccactagtaa taatcgtagg tgataaaatc
    22381 ggtacagcga ttttcgtaaa aatcacccac tcattggcac catcgattct ggcagcctcc
    22441 atcagtgctg taggaaattg actgctatat tgtcgcatca taaacactga agttgtactg
    22501 gcaatcgaag ggatgatcac acctgcataa gtattcgata atcctaaacg actcataatg
    22561 taaaataaag gaatcaatgt ggtaaaaaaa ggcaccatcc tagatagcat aactgtattg
    22621 aacaacagtt tattccccat aaaacgatac tttgctaatg cataacccgc cattgtagaa
    22681 ctggctgtag ctgaaactgt actgattaca gcaataacaa tcgaattcca aataatcaag
    22741 ggataattat atctcgccat gatggcttgc cagtttttta atagcatatc cccaaacttg
    22801 aaattgattc cgccacttaa aatttcttga ttactttgcg ttgaagctac aatcatatat
    22861 aaatatggca tcaaaaatat taaggcacca aacacaataa tgacgtacgt aaaaattctg
    22921 ctttgtatct tttgtttagt catttttatc acctccgaat ttaaattgaa tagccgataa
    22981 tataacagat acaaacacca tcgtccaggc aatagcagag gcttttccaa aatcaaccat
    23041 ttcaaaactt gttttatata aattgactcc tacgaccaaa gctgaatttt ctggtccatt
    23101 ggaagtccca aagaatatat ttgggatatt gaaattaccc aagccattga tagtggctaa
    23161 aactgtggcc attaaaatga ttggctttag catggggatc gttaataaaa agaattgccg
    23221 aaatttcgat gctccatcta tttcagcact ttcgtatatc tctttagaaa tcccttgaag
    23281 accagctaaa aataaaatag tgttatatcc tacactaagc caaatcatcg tgatgatcat
    23341 tgatattcgt atccaaaaag gatttgttaa ccactgtaca ccgttaattc ctagcgcatt
    23401 caaaaatcca ttgaataacc cagtcggatt gaaaaaagtc atgaatacgg aagctacagc
    23461 caccgttgat gtaatggttg gaatataata gacagttcta aaaaatcctt ttccttttaa
    23521 ctgtgctgaa ttcaataaaa cagcaaagta aatagctaat agcatcgtta ttggaattga
    23581 tcctgccatg ataatcaaaa cattcgtgta agatttaata aacaatggat ctcggaagat
    23641 agctagataa ttgtcaaatc caacaaattc aaatgagtag ccaattttca taaaactaaa
    23701 agcaaacgag ataatgatgg gaatcaaaat cgtcacaata aagaaaataa caaaaggtgt
    23761 gaccaatcca taagcacttt ttttatgaga cgtatctgtt gcttttttct tgctgttctt
    23821 tattgtcttg cttggtaacg aagattgcat catcgttaag tcctcctaat attttttaat
    23881 caccagttaa ttttacgccg tacttatgag caaaattttc tgcttctttt agatatgaat
    23941 tttcaaaatc acctgtttgc caatagttat atgcagcggt agtcaaataa gacgtagcat
    24001 ctgaataagt ggctggtaaa acagtatttg atgtattttc attgatttta ttcaatagtt
    24061 catagtattt ttgtcctcct tagtagtcaa actttttctc agctgcttct gtttgatagg
    24121 ccaatgagtt agatgtagcc acgcccagct ccagtgcgtt ggctaagcat tcttcatctg
    24181 tcagcataaa tgtaagaaat tgttgtgcca cttgtggatt tttggcatct ttagggacat
    24241 aaaaacttga tcctcctgat actgcacctt ttcctggatt ttcttttgaa aaaggaatca
    24301 gtggagccat gcgccatttg tcagatgcat caggaaaatt caaagacata ttcgtagcat
    24361 accagccgcc agcaacaaac attgcagatt cttgaaatgc tttctcagca tcttgtgcac
    24421 cgtagaaatg tacaatatct gagtcgatca tttctttgat taactttgca gcatgtttcg
    24481 cttctttagt attcagacgg atatttcctt cttcatcaag caaagattga ttctgctggg
    24541 ctagcatgtt gataaacaat tcttggtccc cagattctgg caaggcaatt ccaaaactac
    24601 cagttttttc ttttaatgct tttgccacct ggatatattc ttcccaagaa ctgatttctt
    24661 caaaatctac acctatttca gcaaattttt ttggttgata ataacaaagt gctggggtaa
    24721 aatcactagc ccaaggaata atcgtttcat tactcgtttg ttgacgcaaa atattcaatt
    24781 tttgatcata aaactgatcg ccatatttgt cataaaatcc atattcatca gcactataaa
    24841 aagcatcttg aaatttttcc agcacacctg ctgctgaagt gtctgccatg gagataatat
    24901 ccggcatatc ttcgtgtgtt accaattttg gggtgatcat ttgtactgtt gctgttcccg
    24961 aagctacatt cacaattttt aagtcaatat ttgctccagt tttgcggtta tagatttttg
    25021 cagcattttc aacatagttt gtcagtttgc cgtttgcgac atatacttct aatgtagtgg
    25081 ctttttttat cattggatct gcgatgtttg ctgttacttc ttcgttagtt tttccacatg
    25141 cacttaagct gaataatagg gtaatgttta gcaaagctat caccaatttg tatctttttt
    25201 tcatgtctat cccttctttc ttttcaagtt cttatataaa acgctttcac ttatgtatat
    25261 taacggaatt agtaacacaa atatttatat aaaaaaatat tttacttgtc gttttggctt
    25321 ttcatttttg ttataatagt cattaattat aaatagaaag ctttttatat aaaaagagaa
    25381 aggaaagtgg ttcttttgtt aacaaacaac caatcctcca atcttgtcaa aaaaacacta
    25441 acctattcca tagataccca tcttcattta tctgctgctc cctattttcg actactaata
    25501 aatgaaagcg ctaatttata tgctgaattt gcacataaat ctatagaact agataatcct
    25561 tcccttttat tcattgataa acagcaagaa gtccaaatct tttctactca aaaggaaaca
    25621 caaactttta tcattatcca gttttatttt gatgagcaat tattagcaca tattacggga
    25681 caatcttttt ctatagatca agaaataaca tctatcatta cttttctgaa aaatgaacag
    25741 ttcaaaattg attatctaaa acatagtaag ccagctattt cctatgatca ggaaatcaat
    25801 tcttttttca tactatgcca acagatgagc attcatttgc tttccttatt agttacttat
    25861 tgtctgcaaa aaattcaatt gtcttcctta ccaaggcatt atcaacagga acttgcttta
    25921 ttgacaatac cttcaaatga gaaagtcatt cctaaaaaaa agcatattct ttattcagat
    25981 gaattagttg atccaatcat acgatattta gaagaacatc tttcagaaaa ttttttgctt
    26041 gaacaattag cccaaatttt ttttatcagt ccagccagct taaaaaaaca ttttagaaaa
    26101 gtgaatggaa aaagtgttat tagctatttt aaagaactaa aaatggaaaa agcaaaacgt
    26161 ctcgtgctag aaaatgaatt aacctataca gaaattgcag atatattagg atttcattcg
    26221 atccatcatt tttcttcagc ttttaaaaaa tatacagggt tatccccttc aaagtattat
    26281 ctatccttaa aatagaaaaa aatttttagg ttttatccac aaattatttc tctatatttt
    26341 ctgtctattc aaaataaaca ataattttcc ggcacaatta tttgctgttt tttaccataa
    26401 catagtacga tcaacgtaga aaaggagatg tttttatgaa agttgttgtc attggcggtg
    26461 tagctggcgg tccttcattt gccactcgtt tccgtcgatt gaatgaagcg cacgaaatca
    26521 ttatctatga acgcggagaa aatatttctt atgcaagttg tgctttgcct tattatttag
    26581 gaggtgtgat cactgaccgt gactcgctga tcgaacgtac accagaaata ttgaaaacaa
    26641 aaaacaacat cgatgtcttt actaaacacg aagtaacagc aatcgatcct tctactaagc
    26701 gattaacagt taaagaccta tccacaaatg aagaaataaa aacagattac gataagttga
    26761 tcatctcttc tggtgctaga ccagattatc cggatattcc cggagttttt gaagcagaaa
    26821 acggctttgt cctccgtagt gtgacggatg cggatcgaat caaatcgttc cttgaagaaa
    26881 aaaatccaca acatgtcgtc attcttggtg caggtgttat gggtctggaa ttagctgaga
    26941 atttcaagca tcgcggctta gacgtgactt taatcgatca attgccacaa gtcgctttcc
    27001 cttatgatcc agaaattgct aatttagttt atgacaaatt gctgaaagaa ggattagccg
    27061 ttcatttaga aacaagagtt actgagatcc gtgataaagg tcgagaaata gtattatcag
    27121 atggctccgt cctttctgct gatatgctaa tttttgctgt tggtgtttct ccgaagaatg
    27181 aagtggtgaa agcaaccggc atacaattat cagatacagg tcagatcatt gttgatgacc
    27241 agttacaaac caatctgccg gacatctatg cgattggcga tattatcgaa acgactagtg
    27301 tagtgactgg tcagccgatc caaagtatgc tttccagtgc ggccaatcgt caaggacata
    27361 tgctggcaga tattttaaat ggtacgccta tgcgctatcg cggatatatt ggtgcaggtg
    27421 tcgcaaaaat ctttgatcat acagcaagtt atgcgggaat gacagaacat gaattaaaag
    27481 catcaggcat aacaaattat aaaactgttt ttatcactcc ctttgaccat gcctatttct
    27541 atccagaagc tacaagatta aatctaaagc tgatttttga tgcagatagc ggtcgtattt
    27601 taggtggaca agcatttgga gaaaaaggtg tcgataaacg gatgggagaa ctttctgtag
    27661 caatcaccgg aaacttgaca gtctttgatt tgcctgattt ggagttgcct tactctccac
    27721 cgtattctac tacccgtgac ccgttgaata tagctggtta tgtcgcaatc aatcaaatga
    27781 cgaatatcgt agaaacgatc aaagcaagtg atatacccga aaacgatttg aaagaagcgt
    27841 tctttttaga tatacgtgaa cctaataaag caccttctgg cagtatctcg gcaacaaaaa
    27901 atattccaat gaatgagtta cgagatcgaa tcaatgaaat cccaaaagat aaaaaagttt
    27961 acattacttt cagaagagga ttgaataatt atacttctgc ccgaatcttg gcaggtttgg
    28021 gtatcaaagc gattttgatt gaagaataaa aaaacgaccg cggtgggtag ccgcggtcta
    28081 ggagttattt ttacttgagg agtaaaaatg aaaaagtata tagggttgtt ggttggtatg
    28141 tatatagaat agaagataaa tgtgaagaaa ttgtgcatta tttcttcaca tttattaggt
    28201 tatagtttaa gaaagtttaa acattgcgca atttaattat tttagctgtt tcttttcata
    28261 aaaaaacatg ttgtgactct gagacaaatc atagtccata gtgatgtctc tagagtaact
    28321 acgcctaata ttacgaggca tcatattaat ctatcagcac tagtacctaa actagcatcc
    28381 ctttcgaata ttttttctta tataataaag tttgctttca ctcctctaat ctcaccaaat
    28441 cgactggctt gcgttgtgtg atactaggaa ctgattggtt tagaacgact tttctattgt
    28501 aatcatattt ttcgccatcc tcgttgtctt ctaatccttc aatgaatgat ccctaatgtg
    28561 tgtattaaat aatttaattt ttttgttcct atttatttaa ca
//
LOCUS       DAZKNV010000034        27868 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000034 DAZKNV010000000
VERSION     DAZKNV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.034"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(416..589)
                     /locus_tag="ACG8M1_001656"
     CDS             complement(416..589)
                     /locus_tag="ACG8M1_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422371.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHLFIFAYILAMIA
                     FLSGGWLIIYLLS"
     gene            complement(592..990)
                     /locus_tag="ACG8M1_001657"
     CDS             complement(592..990)
                     /locus_tag="ACG8M1_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422372.1"
                     /translation="MQLRRNKNYTTIILEDFTDQELLIVGKTKADFIKKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKELYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1206..2261
                     /locus_tag="ACG8M1_001658"
     CDS             1206..2261
                     /locus_tag="ACG8M1_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422373.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2281..2634
                     /locus_tag="ACG8M1_001659"
     CDS             2281..2634
                     /locus_tag="ACG8M1_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422374.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(2816..3103)
                     /locus_tag="ACG8M1_001660"
     CDS             complement(2816..3103)
                     /locus_tag="ACG8M1_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422375.1"
                     /translation="MKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAKLKS
                     DSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3116..3934)
                     /locus_tag="ACG8M1_001661"
     CDS             complement(3116..3934)
                     /locus_tag="ACG8M1_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0422376.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4172..4393
                     /gene="relB"
                     /locus_tag="ACG8M1_001662"
     CDS             4172..4393
                     /gene="relB"
                     /locus_tag="ACG8M1_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFQ0422377.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            4395..4661
                     /locus_tag="ACG8M1_001663"
     CDS             4395..4661
                     /locus_tag="ACG8M1_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0422378.1"
                     /translation="MSYQVRYEREAQKTLKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            4828..5313
                     /locus_tag="ACG8M1_001664"
     CDS             4828..5313
                     /locus_tag="ACG8M1_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422379.1"
                     /translation="MGWYGAYSSANEVIEEKKGYAKNGLEIVDTKVTKTYGIILFKDA
                     EGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFFVGDQEKMVKRQLDRIKEE
                     SNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQDGSLTRFTRLSAGDVKEV
                     A"
     gene            5804..6088
                     /locus_tag="ACG8M1_001665"
     CDS             5804..6088
                     /locus_tag="ACG8M1_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422380.1"
                     /translation="MLKATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6095..6340
                     /locus_tag="ACG8M1_001666"
     CDS             6095..6340
                     /locus_tag="ACG8M1_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422381.1"
                     /translation="MWTLEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            6362..6616
                     /locus_tag="ACG8M1_001667"
     CDS             6362..6616
                     /locus_tag="ACG8M1_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422382.1"
                     /translation="MNYTDEEQITLEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            6698..6883
                     /locus_tag="ACG8M1_001668"
     CDS             6698..6883
                     /locus_tag="ACG8M1_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFQ0422383.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            6950..7345
                     /locus_tag="ACG8M1_001669"
     CDS             6950..7345
                     /locus_tag="ACG8M1_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFQ0422384.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            7362..7712
                     /locus_tag="ACG8M1_001670"
     CDS             7362..7712
                     /locus_tag="ACG8M1_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422385.1"
                     /translation="MKATHLNYFSRTLINNLLKDTTGISVSTKHFANDLIIFEDNNLR
                     IEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKKAKLLFEFQT
                     DYHNELLAQSEILD"
     gene            7734..8108
                     /locus_tag="ACG8M1_001671"
     CDS             7734..8108
                     /locus_tag="ACG8M1_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422386.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTFITLEENLVISDAGIERN
                     IKRVSIKITLNKPTDKKLSEAF"
     gene            complement(8416..8814)
                     /locus_tag="ACG8M1_001672"
     CDS             complement(8416..8814)
                     /locus_tag="ACG8M1_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFQ0422387.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(9006..9773)
                     /locus_tag="ACG8M1_001673"
     CDS             complement(9006..9773)
                     /locus_tag="ACG8M1_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0422388.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(9809..10969)
                     /locus_tag="ACG8M1_001674"
     CDS             complement(9809..10969)
                     /locus_tag="ACG8M1_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0422389.1"
                     /translation="MKITEKNVNPKFEPTESNQKMFDLTVTLSNQLVDSIVEMDAMPQ
                     KIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSSSSKHSRLKQVIEKLHQQSVIK
                     IQRTKTNGKTEYKVISPLEITEFNDFSDAVSIKFSSSIMPLLTNLEDHFTQYTFDQLV
                     NLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDRLKNPVFSIAELRKKFSIEKKY
                     KAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTYTDIKFLLTRTMSVPVPYKQEQ
                     RDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFLISSADLCDLKFMSRLQNKVYP
                     LYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYLEKSITSYLPYVNLYD"
     gene            12018..12821
                     /locus_tag="ACG8M1_001675"
     CDS             12018..12821
                     /locus_tag="ACG8M1_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0422390.1"
                     /translation="MSQEVTENVIDNDVDLVSDQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNVFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQQETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFESFDYEKIYAKKGRKVDRLRFTFSEPESNLPSISMHNWLEED"
     gene            13428..13883
                     /locus_tag="ACG8M1_001676"
     CDS             13428..13883
                     /locus_tag="ACG8M1_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422391.1"
                     /translation="MDAINWHEFVNYMEKLLDDLKSFSIADAVKHGLPVSTTMKMRGL
                     KVPDEIIKLRTKTIIETAKIVDSMNLDLKGKKTTYEKDFVRFLKNVIGKYLGKKSFTE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIVEYLENKEQKKGTKKGR"
     gene            14002..15060
                     /locus_tag="ACG8M1_001677"
     CDS             14002..15060
                     /locus_tag="ACG8M1_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HFQ0422392.1"
                     /translation="MEKDVNSASTKDQYNIIGGLLGDKDKRTRHGLRIMLATFLGVFL
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLTFARSGAEITISDVWTDKTRDVTVVKLG
                     YSGNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNESDSVTKALSQYSMNDVDNEGVISFGKKAKPVN
                     TPDNINFRINPYSDTTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKTINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            15102..17051
                     /locus_tag="ACG8M1_001678"
     CDS             15102..17051
                     /locus_tag="ACG8M1_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0422393.1"
                     /translation="MENSTEFFKNIQTEFNHALTLMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAKRQRQEGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TIIPRLKEYERILKSEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPEASLK
                     LSKKIPDELLEEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDIAKLEEELKSIKGQPVAVYTVTMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRKLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVNDTVSLSNTILFATTNAGAE
                     MYDSMNRYSSLSRVANQENSNEYSTELKREYRKVALEIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAHNEILKSAELVRKHLNVDLRLPPQKKHFYGQEFYADDLSMHLV
                     FDRASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSKAGGFEGKGDT
                     DAEIIAKPSIAESKENKFVFSVGGV"
     gene            17054..20743
                     /locus_tag="ACG8M1_001679"
     CDS             17054..20743
                     /locus_tag="ACG8M1_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3659 domain-containing protein"
                     /protein_id="HFQ0422394.1"
                     /translation="MKFKKSLLQNRKIKRWVVRGLVIVGALAVTLGAPFGMNDPTSDD
                     QGNKQETVANTNVAYAESKPAEKGVWTLYARILMGDKEVNDSATKTGQMNLLGQGGIS
                     ADFPYSDISKQGNAIAGGNAGTQLASTLATYNYYGYIETVSGNAIASQASSFIGGIGR
                     TLGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGKGGSDVSNPVAKALTSLL
                     NNLGLNNQLFKAIASLSMLFFTAILGYQGMKLLSKEGVNSKGLSPVLEKWIVRIFVLF
                     VFLPVAGSLLGVYINGIQSAKEDGKLPTNVVGDYIINTRLWASTQNLAPSSDTGGNVP
                     NGKPTSEIKFVDTDYEPSKKSEMIRMINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NVNTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGNAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTTNNFDATQPWGVANNATFSTQSVALMLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFVRVWEVVLTGSLAAGAGVMAISLGVVTTSLIGLQLPIFLITFVRAFGDTAV
                     GFIPNTLLGDGVANIVRSAMVLGVGYLLVFKKGEKVNNNLINMLIGLPLEVAFGFDER
                     AKLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGRGSVKDMVAGGLGAVGAQGIAD
                     RLNNMGDSNADAKTIADKVVPETPASVPFNGGGVGGTINNTSFKDLVRQDQLRNNSQQ
                     YSDHLGRMVDEKGNFVDENGEVLKDSKFGKDAKGNFIDAKGRLVDEDGNLIDTNGKPL
                     EDNEDGNIGMDSQGRLIDDKGRLVDDEGNLVDENGRKLLNGDFGQDVNGRLVDDKGRL
                     VDEDGNLVDEFGKKLGKHSNGYNVNGDTVDEDGNIIDSRDALVADRNKELEQQQHTPI
                     AVAIPDDESDEVILDQAHQGLREEAKDKVVSDQAQEELKNKSNGEDVSNQYHQTAGNV
                     PVEGQSNELHNNFDNVADRNDTVLKEKESLRQETDKDQSKLKKTTIPTPIGSTVPKVN
                     QANDSETNTGLGMAKDNQSIREPKKTTESSKSNKSKSTSNKTGKSKEPSKAKSAVEYL
                     SKTGKNVYTSADKALAKAPKGSLAGMTYEAKNEAIKLGKGTAKVAKVTAKGATKTGKA
                     VKKSTMSVKDYIAKYSEQKPTDKKS"
     gene            21154..21492
                     /locus_tag="ACG8M1_001680"
     CDS             21154..21492
                     /locus_tag="ACG8M1_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422395.1"
                     /translation="MFDSIKNLVSGMTPEMKTLVQAILYLMATFFALKPGFTAMKHFG
                     DAKWGEGLKYVGAVVAIFIIPVITTVMLLTMGTKTGNDLNQKANMISALIPVVGIYLV
                     TKFPKEEQLG"
     gene            21619..21840
                     /locus_tag="ACG8M1_001681"
     CDS             21619..21840
                     /locus_tag="ACG8M1_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422396.1"
                     /translation="MLVHANEVLTSGFKGTDLAKIMNMNVNQFYDYRNGNKKIEKARL
                     ETLIKFEKAYLYVLDKQKRTIDRKKGVLQ"
     gene            21840..24005
                     /locus_tag="ACG8M1_001682"
     CDS             21840..24005
                     /locus_tag="ACG8M1_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422397.1"
                     /translation="MAKFKDITESINYVAETVPVVVLSLKPQLLEVYQKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYVVIEDVQKLSSEEFPDEEDAILDSEKYVVLLKSSLN
                     YVVDLPEKFKEKLLAGVRFMDSNGQLLVIPDDPNMFEREVEEATDFYSAVDQLEVATK
                     GLERIAETFNSSDAVEFEAVAEAETEAVPDEEEALFEDNDEATEAGNQEASIEETQTE
                     TYQQPKIDEKPESQSDKENYVYEAEKIVSESDVPKNLDADLLEKDFEQIIANKFQPVV
                     LDEVSDPVDLNEEMRSIAELKPLLFLAKESMNARISIANNKINSELNKTKEQLLLKGK
                     QMLADELLRIEEATSLSGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMA
                     KQAYLEAELKKLEQRYDAEHLPEVKQQEDEFRKATEESLDQQYQEAIESIKNDALKQN
                     QEAKEVVVERIINSLKPEIEKSLTEVQEKTLEIVEKTKAENEAEFHDTKEKTTDVVVK
                     YFANKEEVEKLVAKDTNELESKLVAQQNIIEDYKNRVKEFKDLADGYKLNSQKLTEQS
                     EALREDLSRARNDLSQMAEKTKSLVVTTENQTESKRDFTSKKMATIIAVSAMACGTIL
                     GSSYFISHNHQEAQAQTETSISRVENSLGAKTASTSTTDNNYEATPTTEFKVGEDVVI
                     SIDGKTTKAEVLSIDGDKAVVKAPDGNQYKIQAHLTEKN"
     gene            24017..24247
                     /locus_tag="ACG8M1_001683"
     CDS             24017..24247
                     /locus_tag="ACG8M1_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0422398.1"
                     /translation="MREENIVYPVIENQSNTKSSQLLQEVQVVYPVNELPQTNETVSK
                     SISLIGLLIVATALTVGVYRKLKVKGSISDGR"
     gene            24237..25103
                     /locus_tag="ACG8M1_001684"
     CDS             24237..25103
                     /locus_tag="ACG8M1_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422399.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVDWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLRFIFIPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNTARVTMGKKKPFRGTEILKVRQDGTIMYRDGSVALMFNLDGATSLTAFP
                     EEIIAQEGKSIQYQNARDRSLAEIKITSSQPQNTERQIRNMKVQKRNAKSNKAVFDIV
                     DQQERFVSEYIDGVKTTVIQYLILKSQSQMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSEIYALK"
     gene            25121..27079
                     /locus_tag="ACG8M1_001685"
     CDS             25121..27079
                     /locus_tag="ACG8M1_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422400.1"
                     /translation="MELMSRSKLLNFRKKKHKKEQNADSSKAVNNTYVSDLTSLVGYQ
                     FTPSYIRTGNRWGTIVKLVNTYGMNRNYEFGWMVKAIPEVKVEGVKAYLIEADKPVSQ
                     KDQQEIMHENVGGSTNSYENNLNDKNSDAEINKTVMRIIDLNTASLLDSTANKIIDWK
                     LEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSFGGDQRDLFDRLLSEPVGSVYEY
                     TSMSSDFAGNDHAIRKGLDDADGWAIGTMSTSYASGVAFMAMDRSFKGKVLVASHKDA
                     TIKGYSEEISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGETFVAKPSLNSV
                     IEKINLAEEGLNSLELFGDRKDIGDLYRRNLDKLTQIFYLLADRELNPATRVLLKKEL
                     GNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEIDRII
                     VLKDTLRTALDSFSKMFNQRTTLKEIGKSDKLQFYYNLSDLRTEINVMEAQFLNTFDF
                     ITSQAKKGDIVMIHGFDRLSVETVGLIKKRLTMLEEDGVRLAFLFDTIGSGESKDGIE
                     TADIFNTDGKIYQSFESDFNYTIIGKMTSEELMKYEKKVAPARKGEDDQKLSVDLRQY
                     LTSGRSNKFQIRRPADLTNNFVIGEFII"
     gene            27167..27775
                     /locus_tag="ACG8M1_001686"
     CDS             27167..27775
                     /locus_tag="ACG8M1_001686"
                     /inference="COORDINATES: protein motif:HMM:NF012234.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0422401.1"
                     /translation="MKSNIKIIAGDKMKEKENLVWYFNRNPHMLITGRTATGKTYLLK
                     RMADYLSQVGIVSASFDKTEFEEILSSSRKEMEDRFEYIKENRFKMFDVSYSDLDMKP
                     YFVLIDELDSRLLLLEKENPLAYNYLLLIIKDIVLKGRVVGVFFIAVRQGKQPLLESI
                     EDNMLTRIFLGDSKGNGTICFDGNTKKFQTELVTEDFFSVDC"
BASE COUNT         9902 a         4358 c         5174 g         8434 t
ORIGIN      
        1 taatattcta tttttgttat tttattagca ggaaaatcta aatattttta caagaaatcg
       61 tagaaatata ttggtttcgc cttcagatta atactggatc atattaatct gaatacaata
      121 tatgaactaa taaatagctt aacctcgcta ttttgttttt tctgatcatt atctacacag
      181 cattaacaaa tagaatttta aaaataaaaa aagtaagaca aaaaaagtat caacataaac
      241 atatacatat acacgtttat gttgatacac ttaatttgtc ctttaaaaag cactgatttt
      301 taaattgcgt tattttataa cccgaataca gtctgcttgt taggcattgt ccttaaatta
      361 catttttcat aggttattta atcatttaat ctgttgatta ttcttgatct aaaacttagc
      421 ttaacaaata tataatcagc caaccgcctg ataaaaatgc gatcattgct aatatataag
      481 caaagataaa aagatgttcg atcagcttaa accctgatgc gattaagcag accaagtaaa
      541 atagaaattc tcttactgat aatggtaatt ttctaactag catactcata attaacaccc
      601 caaagtaata ttgtattttg aacattttac atccagtaca gcatcaatca accattgcca
      661 atcaaaaata caaggcttca ttgaagtatg tttttcagat gaaaagatat aatataattc
      721 ctttggaata atattttcag ttgttgggat caagctaaat ctaattccat ctaactcata
      781 gctaccagct ttctctccat taaaaatttc cttagcactt tcttctaaag aatcaaaata
      841 tttttcgaca gcaacctttg aagcttttac tattgaagca tttccctttt tgataaaatc
      901 tgcttttgtt ttaccgacaa taagtaattc ttgatcagta aaatcttcta aaataatggt
      961 agtgtaattc ttatttcttc tcaattgcat caggatcact ccttaatata atttatgttt
     1021 ttataatatc ataataagat aaatttacaa gtatttgttt acaccttttt atttacactt
     1081 tattataatt aattatactt ttatgattgc atttttttct tataaacagt tgcaactaat
     1141 agtaaatagg tgtaaactat tttcgtaccg agataccata aacacaaaca gaaagaggtc
     1201 ataccatgaa agaaccatta ttgttttccg ttgacttagg gaataaatca gtaaaagaaa
     1261 tgagtaccca cgtttctcca ctctcacttc cctctcgtat tttgaacaaa aatatcatta
     1321 attcaggacg tttttctaat ataggttcct cattaaaacg atcactaaac gtttctgaat
     1381 atagcctagt aaacactact gaaagctatt actttgggaa ggatatacac gagctaggaa
     1441 aagatgacta cgtgatagaa tcactaggtt ttgggattag cagatacaag caggaaacct
     1501 accaaaatat cctatctttc tctttagcta acctagcacg tttagaagat caatctgatg
     1561 acgttttaac cgttaatcta gttttaggtc tgccttcatc cgactatacc gaaacaatcg
     1621 tcaaatacgt gatgcaacaa gccacacgac aacattcagt tgaagttgac ggtaaggctt
     1681 ataatataaa cgtagatacc gtttgggtac tgccacagcc aatcggaacg ctatataacc
     1741 tcctacttgc tgatgatggt agcgtacaag atgaaacctt gatcagtcag aagatcggtt
     1801 ttgttgatat tggtggtggc acgaaacttt ttgatgttgt ccaaaatttt gaaattgacg
     1861 aaaacaatcg tgaacaaaag gataccggca tttttacttt atataatcgt atcgtaaata
     1921 tgcttgacct tccgatcagt cctaatgctt tccaacttga aaagattatc cgagaaggca
     1981 aagaaaaagg cgtatatcta tttaagccaa gcggaaatga aagttttgat atttcagaag
     2041 tagttgaaag agaaataaaa acatacacaa atatggttgt tgcagaagtt ttagctacat
     2101 tcaaaaactt cacgacctta gataaagttg tctttactgg tggtggagct tctattatcg
     2161 acaaacaact tgtaaaagat aaaattccgc ataccttgtt tgttgaagac agtgaatttt
     2221 ctaatgtaaa aggcttttac aagtttggtt taactcaata aaacagcgaa ggagatcaac
     2281 atgaataagg gaaaatcaga gcgttatgta gttataatca atagagaaaa ggttagcgag
     2341 ttacctttag cagagtttct tgaatccgaa tatgaaacac taggcgttaa atactctcag
     2401 acgatcaaaa aagctttgaa cctatatcgg cgtgtaaaga acaatgaagt tacaattatt
     2461 gaagcaggca acgatagaaa cgatagcaaa gtagcagaag taaagaataa accaactgat
     2521 cataacccta ttcaacaaga gcatccttca acggttacat ccgatcattc agcaaagaaa
     2581 gaaaagccaa tgctaaaagg gttcaatgca ccaagtaaca aagacttact ttaaaatgaa
     2641 aaaggcgagg ttacaatacc tagccttttt attatgtaca aatataaaca taaacatata
     2701 cgtatacatg tatataaaca tgtatacgta tatatccata aacacgtata tgaaatttag
     2761 ttaagctata cctaaccgct tattccaata aaaaaagtga tcagctttaa actgatcact
     2821 caccaaaaac ttcatcatac aagttatcta tcatttcacc aagtaaagct gaatctgatc
     2881 gaattcctaa cttttcgctg attttagata gcttctttct ttgcgatggt tgaagcgtga
     2941 attgataatt tttcttcttt tcagaactat cactttttag tttagctacc aaagaacttg
     3001 ttgtttcttt aggtgtttgt ttaggttctt caactgcttc aaccacttca ggaacttctt
     3061 ctacttcagc ttcagcgaat tttttaaatc tattttcttt cacttcaatc actccttatt
     3121 cttgtgccgt atcaattatc ttgttgtata gcgtaaacgt gctttcaaag aaatccttat
     3181 tcttacgata gatattctta tccttagcga actcagcaat attcttacct tctaagctag
     3241 ttgcattaag caattccttc tcttgtacat atccaagata attagataac gttggtacca
     3301 attctaggaa ctcacgactt gaattagtat tatgtttgat cctgctaccg atcgtagcgt
     3361 atttagtttc catcagtgtt tcaccagtct taatatcaat caactgtttt gctagtgcat
     3421 caatatcttt accaagcttc agcaaagctt caaaaccatc tttagatgga tcagaaatgc
     3481 ctacgacaag atcagataca gcccaagcat tttgagctag tagacctgca tcattatgag
     3541 tatcaatcag aattagatca tacttctctt taagctgttc atagttaaca acgatccatc
     3601 taaacagtag ggttctgttg ttaggcatat cacgcatttg catctcaact tgttttaaat
     3661 cttcacctgc tactaaaata tccatgttct catttatagc taaaggttca gctgatccat
     3721 gaagatataa atgattgatt gtattctctc ttttcgcttt actgaaagca tcaggaaagc
     3781 gttttgatag gttttgcgac ttatcttcat caatatacag caccttcata cctaaatttt
     3841 cgacagcata tccacctaga ttgtagattg ttgttgtttt acctgttcca cctttttcaa
     3901 tgtttccagt aatgattgac aacttctttt ccatgattaa acctccctta ttaacctttt
     3961 gtaactccat tatacactat aaacaccttt atgtatatgt ttatatacat aaaggtgttt
     4021 atatttatat ttgcttttat attctataac ataaacatat atatgtatat gtttatgtat
     4081 atgtttatgt ttatgtatat gttcatatat ataactattg catctgtcat acaatcgtag
     4141 tacaatgtaa ttgaaaagga gttgataaac tatgccagta ataagtattc gtgtatctaa
     4201 agaagaaaaa gattttcttg aaaaagttgc tgaattcaac ggagataaca tttctgaatt
     4261 tatgcgtagt aattccctgc aaacagcaga aacgttagta gactttgcta cctacaagga
     4321 actaatgaaa gagcatgagg aaaacgatca aagtatttcc cacgaagata tgctaaaaga
     4381 gttaggctta taagatgagt taccaagtaa gatatgaacg tgaagctcaa aaaacgctaa
     4441 aaaaaatgga taagtttcag gcaaaggtta tcctaaactg gatcgagaaa aatcttgtag
     4501 gcactgatga tccaagaaag catggtaaag gtctaacagc taataaatca ggctactggc
     4561 gatatagggt aggtgcatac cgtataatag ctgatattag cgagcatgaa gtgacaattc
     4621 ttatattgtc tattggtcac agaagtgaag tttataagta acagacaagc tgataaggct
     4681 tgtctgtttt tttgttaacc caacaaaatc actgtttacg atcccacttt acctaaaaaa
     4741 gaacaatatc ctcttgttat tatacacacc agtgtgtata atataagtgt aaacaagcta
     4801 attaactttc aaaaggagcg attttttatg ggatggtatg gtgcttattc atcagcaaat
     4861 gaagtaatcg aagaaaagaa agggtacgcc aaaaatggtt tggaaatcgt agataccaaa
     4921 gtaacgaaga cctatggaat tatccttttc aaagatgcag aaggaaccta cgatattgac
     4981 agcttcatct ttcgagatga aatgtacaaa ccaatctact tcttaaatga cagtcctgct
     5041 tactttaaga aaattccaaa aaaatggttg aaattctttg tcggtgatca agaaaaaatg
     5101 gttaagcgac aactagatag aattaaagaa gaaagcaata aaccaaaact tgatgactta
     5161 ttagttgcag gtaaaactta ctcaatctgg gatggatcgt atgtcgctgt ttatcagtat
     5221 aaactcaaac gtagctttat tttccgacta caagatggat cactcactcg gttcactcga
     5281 ctatcagcag gagatgttaa ggaagtagcc taaaacttaa atacataaac ataaacgtgt
     5341 atacgtttat gtttatgtat atgtatatga atataaacgt attaggtacg aacgctttta
     5401 aatgcttttc tgggctttga ttttagggta gggctaaaac atcaccatct gatccaaaac
     5461 agctcagaaa cgcatttaaa cgtatctgat accaatatta cagaaggagt gtatcgtatg
     5521 attaacctat ttcttttagt gacagctagt acattattct ttactggaat atcacttata
     5581 atttcctatt tgatctataa gaaagccgaa acttacacaa gcaaagcaac cggactagcc
     5641 gtttcatcct ttttaacttt gctgactttt tttgttactc tatcgttttc ttttgtttag
     5701 cacagctgat ccatcagcaa aaaacctctc tttacattat acacactagt gtgtataatg
     5761 taattgtaaa caagctaatt aacttttagg aaggaatgac aatatgctaa aagctacatt
     5821 acagcaacct actcacgttg ctattgcaga aagctataca attaatgcag gggtcgttaa
     5881 acagctgatc aaggatcgag aattcaaaaa gtttaacagt cgtcaagcgt ataacagaca
     5941 gttaaagaaa gctattctaa agcacaaaaa ttccttcatc gggaaattgg aaagtgtgga
     6001 tgttaaaact gtttcaacgg cattttcagt tgttgaagtg actattgacg gtcgcttgat
     6061 ttctctattt gcttttggaa ttaattgata gggagtgtgg actttggaag gtaagacttt
     6121 tgcagaaatt tggactgaat ttattgaggt accaactcgc attgatccga taacttctga
     6181 aaaggtattg gatgcagact tctacaatct caaagcaggt actagccttg aatgcgtttg
     6241 gatgtattta gaagagcatt tcaaaggcgt aacgctcggt cacgtcttat accacaatgg
     6301 tgccgagtgg gatgcaattg gaaatatcca tttttcttaa tacaagaaag gagaacacaa
     6361 tatgaattat accgatgaag aacaaatcac tttggaatac gttttcacaa atgaagaagg
     6421 ggaggaaatt gaaaaagtct tgatcatttc atcaaaagac ttggagaagg ctttggctta
     6481 tgaaccatac gaatcaaccg taactgtcat tgaattctta gatacctata cttctaatga
     6541 tacttgggaa attatgaata tttgcaacgc taataacatt caatttgctg aaaaaaccaa
     6601 taaatcattt tattagtttt gcaataaaac atcctctttt tctattgatt ccatacacaa
     6661 caatgtgtat aatagatttt gtaaagggag ggtagctatg cctaagacag caagagaaat
     6721 tgtaaaaatt ctcaaatcta acggcttcaa aaagactgga caaactggca gtcatgcaaa
     6781 attttataat tccaagacta aaagaacggt cgttgttccg atccacaatg gtgatgtacc
     6841 actaggaaca gaagctaata tctggaagca agcagggctt taacagcctt gccttcctat
     6901 ttggtattag gcatactatc ctctcttaca ctagaaaagg agcgaggaaa tgaagacaaa
     6961 aaatattttt tatccggcaa tcttcgagaa agaaggagaa gcttataaca tcgttttccc
     7021 tgacttaccg gaaatatcta cctttggaaa tagtcttgaa gaagcatatt taaacgctaa
     7081 ggatgcttta ggattagcgc tatatagtgt accagatgca gaatttccta aaccatcagc
     7141 agtggaagaa ttaactttga aagccaacca agtggtagta atcatccaac taaacattaa
     7201 acttttccga agaagcttaa atacaaaaac aattagaaaa aatgttagtg ttccggaatg
     7261 gttagttctt ttagggaagg agaaaaacat aaacttctct caactacttc aaaaagcact
     7321 agaagaagag ttgcttgaaa agtaaaaagg agaccgaacc tatgaaagct acacacttaa
     7381 actatttctc tcgaacgtta atcaataatc tattaaaaga tacaactggc attagcgtta
     7441 gtaccaaaca ctttgccaat gatctaatta tttttgagga taataacttg cgaattgaga
     7501 tgtttattga acaggcaacc cctaactcaa tacctgaatt ctgctatacg cacactgaaa
     7561 aaatgaaaca tgcaaaatca gttaaagatg ttgaagcatt aagtgaatca ctaacgaacg
     7621 ctttaaacct cgttaagaag gcaaaattgt tatttgaatt tcaaaccgac taccacaatg
     7681 agttgcttgc tcaatctgaa attttagatt aattgaaaca ggagaagaga aagatgaaac
     7741 aaacacaaac agaaaccgtt aacgatacgc ttgctgatca attagcaggt tattataaat
     7801 tatttgagat gagtaaagca cagcgcttga tccactatct ttggaaatac aaaattttgt
     7861 ttcttttttg ggaagcaaca ctaacattct cagttctttt ttataagtca gatttttata
     7921 atcaacactt agttttaggg agttttttgc ttatctacac cattttgatg cttaatttat
     7981 ataccttcat cacacttgaa gaaaacttag taattagcga tgcagggatc gagagaaaca
     8041 tcaaaagggt atctatcaag atcacgttaa acaagcctac cgataaaaag ctctcagaag
     8101 cgttctgaga gcttttgaca tttgcttgta taaaatttat cctaacacat tacaaagcac
     8161 ctaattcgag cttatatcaa gcaaatttgc tatttattac tcaatacata tctaaaaatt
     8221 acttgatgga aaactagata catggtaagc atgaaaagaa aatcaatttg agcagatgca
     8281 gtataataca tagcaattta aaagctctca gaagcgttct gagagctttt aatatattct
     8341 ttgataattt gtctttctta aatccatacg tcctaaaaca agctgttatt gcttaatatg
     8401 atcatttgag agacatcaaa tcaacttttc tctcaacaaa tcattcaaag ctttcgacag
     8461 attaatattc tcttcagccg ctaaaacatt taaatagtgt tccacagtca ctgattttcg
     8521 atcgtaattt tgcttgtttc gagctttagc aactttcgta ttagctttta cgacaaataa
     8581 attaacattc tcagatcgct tgattcttgc atttaactct tgaacaggcg taggcgatgg
     8641 aatttctttt tcttgcaact ctaaaagcac caagtatcct tccaatactt cttgcgccat
     8701 ctcaaaagca tcttctaaag tttcaccatg cgtatataag tctggaaaat ctgggaattt
     8761 aactgcatat tcatttcctt tccattcgaa tactgcacaa aaaaagtatt tcatcgcatt
     8821 gcacctctct aattaaaaaa taatttttgc tttttagttt caaaaaaaag aatcgcctac
     8881 caaaaaaatt gataggcgat cacaagctaa ttaacctcta aaggagatta ataccttgct
     8941 cccaaggcac tacatatctt agcatacgtc tgaagcatct tcaaacgagt aagatatatt
     9001 ttgcattaac ctaatttttt ttctctataa ggtttttcat caaactcact agaaatatta
     9061 aactggacag caaaattgta atttctgcct tttctaactt tagcaaaatc aatcttcagc
     9121 attgattttt cattaatttc ctcaactgat tcccttaaaa cacgtctatc aaaattcgat
     9181 attgttttat actcattttc tgttttcgta atctcacgaa ttttaactat ttcaatcagg
     9241 ggattcttat atatttcagc tttctcaaaa tctcctttat ttttggcgat aagatatttt
     9301 ttataataca tcgccaaata tttgtataac acgatgctat attttttttg aaaagatgct
     9361 aagtcttcaa aaacaaagaa cggatacttc tttttgattg agacaattaa gggaattaca
     9421 tcttctgaaa aactgaaaga tacactatgc tcttctaaat cccaatgaat ccgatcaata
     9481 gcagatacag ttgtatacgt cttatatttc ttgtctagat tcgatatttc ataaactgct
     9541 tgtctttgca aagtgttaac tatggttttt agttcagttt caagattttg atcaacatcc
     9601 atgtaattaa taatcgcttt aacaggtaaa tctactacgc ctgttttctt tagctttgtg
     9661 ggcgagatat aactgaacag caattgataa agttcatacg actttaaatc cattttcatg
     9721 tcaattgttg ctaagaactc ctcgttgtac tttgtcagtt catctttttt caaaagcttt
     9781 tccttccttc acgcaagttt ttcagttgtt aatcataaag gttcacataa ggtaaataac
     9841 tcgtaattga tttttcgaga tatttaacag tattttttat tgtgtaatcc tccttatgag
     9901 tagcaacgta agatagatga ttgacaactg attcaaatcc tctatctttg gataaacgat
     9961 cataaagcgg ataaacttta ttctgaagcc gactcataaa tttcagatcg cataagtcgg
    10021 cagaactgat caaaaagttt ttgattagta atttagtgta tttgctattc atagctttca
    10081 agtacgattg attcattttc tctgttttat cttctgcgcc ttttaaataa gcagggtctc
    10141 tttgttcttg cttataaggt accggtactg acatggtacg tgtaagcaag aactttatat
    10201 ctgtataagt atgacccttc ttgataagct catagtcaat tttaaaatca gtgtatttat
    10261 tcagttgggc aatcggttct ttaattacac gtctttcaaa gtctcgaaaa gctttatatt
    10321 ttttctcaat actgaatttc tttcgtaact ctgcaattga aaaaacgggg ttttttaatc
    10381 tatcaagtga ttttgtactc catgttaagt tatctctatt tgcttcatac agattaaaat
    10441 ctttagtgaa taattgaaaa aaactgatcg catatttgct tgtcaagtta actaattgat
    10501 caaatgtata ttgtgtaaaa tgatcctcta agttcgttaa caaaggcata attgaactac
    10561 taaatttaat agatactgca tcagaaaaat cattgaattc agtaatttct agcggtgaga
    10621 tgactttgta ttcagtctta ccgttagttt tagttctttg aattttaatg acagattgct
    10681 gatgcaattt ttcaataact tgttttaatc ttgaatgttt tgaagaagat gaactagaag
    10741 acatcaacgc aaataaagcc tttttagata ctttgacggt attattaaaa ggcggatttt
    10801 tagggtcaag atgtcctata gcgtaaagat aaattttttg tggcatagca tccatttcaa
    10861 caatgctatc tacaagttga ttcgataaag taacagttaa atcaaacatt ttttgattgc
    10921 tttcggtagg ttcaaatttc gggtttacat tcttttctgt tattttcata cgattgcctc
    10981 ttctttctaa gcttggtacg agcttaaaaa cttggaactg gtacgattcc attgaataag
    11041 tatagacctg ttttcgatac gatacaataa gaaatgtatc gtaaatttat aacataactc
    11101 aatctcagta aaacgcattt tatttttatt aatcaaattt cattgataag acagcagaaa
    11161 tcgctatttt agaaccttta caaaataaaa atccttttca aaaaaaatac gtaattataa
    11221 aaattcacaa aattaaaaaa caaatatttt tttagttttt agaaataaat tcacatactt
    11281 tgtctttttt tgtatatatt cggaatacca catcgctttt tgtccatgtt tgcatcgctt
    11341 tttgtccaca ttcacatcgc tttttgtcca tgttcgcatc gctttatgtc caccctaaaa
    11401 tctatttaag attgatataa agcctttttg gaggttgcta aagttttaaa gattaaaata
    11461 tatattataa atataaataa aaggggaagc tgaagcttcc tccttttcct ttttttcaat
    11521 tattcaaaat tacacaagca aaataaattg ctagatagtg ttagtttttg ttttaaggtt
    11581 tttaattttt gagattttga aataagagag gaggaatcct cctttattaa atatctgtta
    11641 atatatctgt taaatatctg ttaatatatc tgttaggggg gtcttaaacc cttgggagag
    11701 taagtattga aggggtatga aggtaacact tttggacagt aaaggtaaca aaagtggaca
    11761 gtaagggtaa catttttgga cagtaaaggt aacaaaagtg gacatttgag gtatcaaatc
    11821 aggataagac gttaccttcg gttttcttga tttggaaatc taaaaagtag aaaactagat
    11881 tagtaacaaa tctttgttga ctgttacctt tagttgtgat ttaatttagg taacaagcag
    11941 aaaaaaagcg tttcctttaa tttagtacca aattaacatg attaaaggga tgcaacaaga
    12001 agattggaga gtaatcaatg tctcaagaag ttaccgaaaa cgttattgat aatgatgtag
    12061 atttagtatc agatcaaaca aatgcaattg ttcgttataa caatggtttg aacacaacag
    12121 ctttgcgagg atttaaacct gtagaaatgg atgtgttttg ggctatttta tcaaaaatga
    12181 aacgtcaagg aacagcagaa gtaacttttg atttcaacgt ctttcgttat ttggtcaaat
    12241 acgacagaag agaaaaggac agtttttatt ctgtgttaaa agctttgagt gacaaactag
    12301 gtactttaac ctaccgcttt gaagattcag atgtctatga acagctgtgg ctttttcaaa
    12361 aattccgaat agataaacag caagaaacag ttacaatcaa ggcaaatgag gagtttgaat
    12421 ttatcttaaa ttcaattggc aaaaacttta ctcgttttga acttgataac tttacaaaac
    12481 taagaagtag ctacacaaaa gagctgtatc gtcatctcat gcaatataga aataaagagt
    12541 ggcgaaatgg ctattgggta gtcaaagttg aagattttag aagagcgtta agtattcctt
    12601 caagttacag aatgacaaat attgacaaaa gaatattaga gcaggcgaaa gaagaatttt
    12661 tagctcctga tgaaaatggt atacaggtat ttgaatcttt tgattatgaa aaaatctatg
    12721 cgaagaaagg aagaaaagtt gatcggctca gattcacttt tagtgaacca gaatcaaact
    12781 tgccatccat ttcaatgcat aattggttag aagaagactg aaaagaagca ggttgtaatt
    12841 ttaatacaac ctgcttcttt tgaaaaaagt atgggtaaca cttttggaca ataaatgcaa
    12901 gaagtttttt tgtgaccaaa ctttatatta gattactgtg attttgtgtg ttagaaaagc
    12961 cctgatagaa aagcaaattc aaacactttt taatatgtat gggtaacact tttggacatg
    13021 tcaataataa atatattttc tttcgtcttt tgcctaacta aaggtaacac ttttggacag
    13081 tatagttttg taaactaatt agatcgggtt taatgggata tatcttagca tttatgtaag
    13141 aatgaaggta acattaatgg acatgtcaac tgtttgaaca aaaaaatata gaatatttgg
    13201 atctgatttt tcatttttcc aaacgttaaa aaatagttag ttattttatt aatagatagt
    13261 catccttaat gtttgaaata gcagaaaata agatattgtt tgataaatgt tgttgttata
    13321 aggaaaactt gaatttgtta attgatttat ttatgttatt atgatactat aataacataa
    13381 atgtgttacg cccgaacctc attttacaaa aatgaagggg tgagacaatg gatgctatta
    13441 attggcatga atttgttaac tatatggaga aactactaga tgatctgaaa agttttagca
    13501 ttgctgatgc cgtaaaacat gggttgccag ttagtacaac gatgaaaatg cgagggttga
    13561 aggttccgga tgaaattatc aagctgagga ctaaaacaat cattgaaact gcaaaaattg
    13621 ttgacagtat gaaccttgat ttgaaaggca aaaaaacaac ttatgagaaa gactttgtac
    13681 gttttttaaa aaatgttatc ggaaaatatc tagggaaaaa gtcttttact gaattgagag
    13741 acgaagagat tgtaccaact ccaatggtta gcaaaattcg caaaaacaaa gccgagggaa
    13801 attactatct tggcacaata gcaaaaatcg ttgagtattt ggaaaataaa gagcaaaaga
    13861 aaggaacgaa gaaaggaaga tagttcgtgt gataaatatg aatagggaag aatgtaccga
    13921 aatgataaaa aaacccgaac ctagaattac cgaaaaactg actgattgct tgctctttta
    13981 cgaaaggggg caggcaaact aatggaaaaa gatgtcaatt cagcatccac taaagatcaa
    14041 tacaatatca ttggaggatt acttggtgat aaggataaga gaacacgtca tggattacgc
    14101 attatgcttg cgacatttct aggggtgttt cttttattaa caggcttggg tagctacatt
    14161 tatcaattag gaaactataa ttattatctt gtcaacaata caacaccaat cggctcatca
    14221 ttgacgtttg ctcgatcagg agcagagatc actatctcag atgtttggac agataaaact
    14281 agagatgtaa cggtggtcaa acttggttac tcaggaaacg caagaaaatt gctatctaca
    14341 caaggtaaaa attataactt gtatatggca acaaaagaaa aagatcgtcc taagaagctt
    14401 gaaatgagtt atgggatgtt aagtaccgat ggtgatgctt tcttgttcct aaaaggtaaa
    14461 ttagatgaaa gagcttatca agtttttatt gctaaccaag tatcactaat ttcaggtgat
    14521 gatacagctg atgatgatac caaagtcaat gtgaatgaat cagattcagt caccaaggca
    14581 ctttctcaat attctatgaa tgatgttgat aatgaaggag taatttcttt tgggaaaaaa
    14641 gcaaaaccag ttaatactcc tgataatatc aatttcagaa taaatccata ctcagataca
    14701 actaacgtat atcaaggaag cttccttacc aaagatggcg atattgatta ctcaaaagtt
    14761 gtagctgtga caagtaagaa taatgttgta aataagctag aagaccagtt aaatgcttca
    14821 aatactaaca tcaagaaaat cgaagccaca aaagctgagt atcttgaacg tttacaacaa
    14881 aatcctgacg ataaagattc gcaagaaagt attcgtcaac tagacagtcg aatggagacc
    14941 gaaattaaaa caatcaatga tacacaaaaa ttgattgatc agtacaaaaa tgctgacttt
    15001 aacaaagatt cttttggaga tatgaagaca acatttaagt acctaaccct gactgactag
    15061 aaacaaatta ttcttatttt agaggaagtg aacacaaaca gatggaaaat agtaccgagt
    15121 tctttaaaaa tattcaaacc gaattcaatc atgctctcac actaatgaaa ccaccgaaac
    15181 ataagttagt ggggcgtgat gacgaactcc atgagttgtc actgatctta aatagaccgg
    15241 aaacaccaca agctatcttg ttaggtgaag caggaacagg taaaacagca ctggcaagtg
    15301 aatgggctaa aagacagcga caagagggga agaaagtaca agtatataaa ttatcaatcg
    15361 gacaattgcg agttggagga gatgacgtcc tccaaacacg tttggaaact ataattccaa
    15421 gattgaagga atacgaacga attttaaaat ccgaggacaa agataatgaa tttgtcctct
    15481 ttatagatga atttcataaa gttgtcagtt catttgggag cggtaataaa attgggggag
    15541 attcgctgaa ggaaccttta gcaaatgaat cacttcagtt gataaccgct acaactagaa
    15601 aagaatatga aaactatatc aaacgagatg atgctttagg tagacgacta caaccgttag
    15661 aactcaacga attaaaaagt gatgtcgttg tcgatatact aagacaatgg ttgaatacat
    15721 catctgtcaa agatgatcct gaagcttcct tgaaattatc caaaaagatt cctgatgaat
    15781 tgcttgaaga aatcgtacaa gcaaacaagc tttatcgtga ggatttatcc gaaccggcta
    15841 aatcaattgc cgtaatggaa gatttgattg cgaaggatcg tgtagatggc aatgcgtata
    15901 atcgagaaag cctgttacaa atatttggaa aatataatat tcaactagat tctgattttg
    15961 atatagcaaa attggaagag gagctaaagt ccattaaagg gcaaccagta gcggtatata
    16021 cggtcacgat gttgtttaaa cgaatgaaac ttggatttga tcgttttaaa gggcgaaagc
    16081 aaccaaaagc aacggctttg tttacaggat caacaggggt cggtaaaact gcgatggcta
    16141 aagctgtagc aagagggcta tacggtgatg aaaataaagt ccttttagta aatatgccag
    16201 actataaaac taaagatgat gctatgcggt ttagaaagct tatcggaaca catgtccggc
    16261 atgatccatc agcaatcatt gtttgtgatg aatatgaaaa agcaggcgta gaaacacttg
    16321 atgccttttt atctattcta gatgaaggaa gaatcagttt tactgaaaga ggatgggatg
    16381 atcgagaagt taatgatacc gtctcacttt caaatacgat tttatttgcg acaacgaacg
    16441 caggggctga gatgtacgat tcgatgaacc gatacagctc actatctcgt gttgctaatc
    16501 aggaaaattc aaatgagtac agcactgagc ttaaaagaga gtatcgaaag gtagcattag
    16561 agattaaaca agctctaatt ggtgaaggtc taaaacccga agtcatcaac cgatttggac
    16621 ggattgttcc attttgggct ttatcggaac aaactctttt ggaaattgca cacaatgaaa
    16681 tattgaaaag tgctgaattg gtaagaaaac acttaaacgt agacttacgc cttccaccac
    16741 agaaaaaaca tttctatggt caagaatttt atgcagatga tctctccatg cacttagttt
    16801 ttgatagagc ttcacaagaa gattctaaat cagggggtgc aagaaatatc ttgcatctgg
    16861 tcgaatcaga atttgaagaa gcaattactg aagcaataat tacctatcct aacgccaaaa
    16921 tatttgacgt taaattgagc aaagcaggag ggtttgaagg gaaaggcgat acggatgcag
    16981 aaattatcgc taaaccttcc atcgctgaaa gtaaagaaaa caagtttgtg ttttcggttg
    17041 gaggggtgta gctatgaaat ttaaaaagtc tttacttcaa aatcgtaaaa ttaagcgatg
    17101 ggttgtaaga ggtttagtta tcgtgggggc acttgcagtt actttaggcg ctccatttgg
    17161 aatgaatgat ccaacgtctg atgatcaagg aaataaacaa gaaacagttg caaatacgaa
    17221 tgtggcttat gctgaaagta aaccggcaga aaaaggggta tggacactat atgctcgtat
    17281 cctgatggga gataaagagg tcaatgatag tgccactaaa actggtcaaa tgaatttact
    17341 tggtcaagga ggtattagtg ctgactttcc ttattctgat atttccaaac aaggtaatgc
    17401 aattgccggt ggtaacgcag gtacgcaatt agcatcaacc ttagcgactt ataattacta
    17461 tgggtatatc gaaacagttt caggaaatgc gattgcaagt caggcatcct cttttattgg
    17521 tggtatcggt agaacgcttg gcagttttat cggatcaatt agcttgatac tttctaatat
    17581 tgctgaatcc atcaatgaac tccttggaaa atttttcatg agtatgaata tattttcact
    17641 tatgggttgg ggtaaaggtg gatcggatgt ttctaatccg gtagctaagg cgttaactag
    17701 cttacttaat aatttgggat taaacaatca attatttaaa gcgatagcaa gcttatctat
    17761 gctctttttt acagcaatac taggctatca aggaatgaaa ctgttgtcga aagagggtgt
    17821 taactcaaag ggattatcac cagtacttga aaaatggatt gttcgtattt ttgtattgtt
    17881 tgtttttcta ccagttgcag gatcgttatt gggagtttat atcaatggta ttcagtcagc
    17941 aaaagaagat ggaaaattac caacaaatgt tgttggtgat tacatcatta atacaagact
    18001 ttgggcttct actcaaaatc ttgctccatc atccgatact ggtgggaatg tgccaaacgg
    18061 aaaaccaaca tctgaaatta aatttgttga cactgactat gaaccatcta aaaaatcaga
    18121 aatgatcaga atgatcaata ctagcagtta cgctagacaa aataatgatc tagattccaa
    18181 ttcagtcggc atggcattgt taaaagaatg gtcaagtaat gatacgttta atgtcaatac
    18241 ttatgccggt gatgtgaatg tagctgaaaa tgatgcttat atgggaagag cgcctgctgt
    18301 ttggacaggc tataatttag gggatggaaa agaaggaaat gcaattaaga aacctaccaa
    18361 tttaaatggt tatatttggt cagctaatca aaacgttaca gacgacaacc gcaagcctga
    18421 tggaaaagga acaacgaata actttgatgc tactcaacct tggggtgttg ctaacaatgc
    18481 aacgtttagc acacagtcgg tagcgttgat gctccaatca gcactggata catcaggggc
    18541 taagttttat gcgtataata tcgctccatc aggaattcaa ggtagtgcta agaatatgtc
    18601 aacagtaaag acagaatggc gtacagcttc tttagttggt catggagcta tgggtaaatt
    18661 cggctcatgg ttagcgatga acgctgaatc aatcgtatta gcagtgcttt atctagcttg
    18721 tgcttgggcg atgtttaacg ttaatattgt aaaagccttc aaacgtgagt ttgtgcgagt
    18781 ttgggaagta gtcttaacag ggtctcttgc cgcaggagca ggggttatgg caatctcatt
    18841 aggagtcgta accacatctc ttatcggatt acaattacct atttttctga tcacctttgt
    18901 tcgtgcattt ggagatacgg ctgtaggatt catccctaac acattacttg gtgatggtgt
    18961 agcaaatatt gtacgatccg ctatggtctt aggcgtagga taccttctag tctttaagaa
    19021 aggtgaaaag gttaataata atttgattaa tatgcttatt ggattaccac ttgaagtagc
    19081 gtttggtttt gacgaacgtg ctaagttatt atttggcaat agaaatgatg ctgttcgagt
    19141 tgtggatggc gtttctaaag caatcaaaaa aagccaaggg gctaaaaatc cttattatga
    19201 tggtggcaga ggatcagtaa aagatatggt cgcaggagga cttggagcag tcggagcgca
    19261 aggaattgct gatcgtttga acaatatggg agacagcaat gctgatgcta agacaatcgc
    19321 tgataaagtt gttcctgaaa cgcctgcttc agtaccattt aatggtggcg gagttggtgg
    19381 aacaatcaat aatacctctt tcaaagattt agttcgtcaa gatcaattac gtaataactc
    19441 gcaacaatat agcgatcatc taggacggat ggttgatgaa aaaggaaact ttgtcgatga
    19501 aaatggtgaa gtattaaaag acagtaaatt tggtaaagat gccaaaggaa actttattga
    19561 tgccaaaggg cgtttggtcg atgaagatgg aaatttgata gatacaaacg gtaaaccatt
    19621 ggaagacaat gaagatggaa acatcggtat ggatagccaa ggacgtttaa ttgatgacaa
    19681 agggcgcttg gtcgatgacg aaggaaacct tgttgatgaa aacggacgta aattacttaa
    19741 cggtgatttt gggcaggatg tcaatggtcg tctagttgat gataaaggac gattagttga
    19801 tgaagacgga aatctggtcg atgagtttgg taagaaactt ggaaaacaca gtaacggtta
    19861 taacgtaaat ggcgatacag tcgatgaaga tggaaacatc attgattcaa gagatgctct
    19921 tgtagcagat cgaaataaag aactcgaaca acaacagcat acaccaattg cggttgcaat
    19981 ccctgatgat gaaagcgatg aagttatttt agatcaagca catcaagggt taagagaaga
    20041 agcaaaggat aaagttgttt cagatcaagc acaagaagag ctaaaaaata aatcgaatgg
    20101 tgaagatgtt tcaaaccaat atcatcaaac ggctggaaat gtacctgttg aaggtcagtc
    20161 taatgagctt cacaacaact ttgataatgt tgctgatcgg aatgatacag tcttaaaaga
    20221 aaaagaatca ttaagacaag aaacagataa agaccaatca aaattgaaga aaacaactat
    20281 tcctactcct attggttcaa cagttccgaa ggtcaatcaa gctaacgatt ctgaaacaaa
    20341 cactgggtta ggaatggcga aagacaatca atccattaga gaacctaaaa agacgactga
    20401 aagtagcaag tcgaacaagt ctaaatctac ttcaaataag acagggaaat ctaaggaacc
    20461 atctaaagct aaatcagcag tagaatatct atctaaaact ggtaagaacg tgtatacttc
    20521 agcagataaa gctttagcaa aagcgccaaa aggaagctta gcaggaatga cctatgaagc
    20581 taagaacgaa gctatcaaat taggtaaagg aactgctaaa gttgccaaag taactgctaa
    20641 aggagcaact aaaactggta aagcagtgaa gaaatctacg atgtcggtga aagattatat
    20701 tgcaaaatat agcgaacaaa aaccaaccga taaaaagtct taagaagaat aaaaagaggg
    20761 agcattaata tgctccttct tttttgttct tctcttcaag gggaatgtca agaaaaactt
    20821 aattgtcttc aaaaatttct tttttatttg gtagtaaatc tatgaaatat ttgctttttt
    20881 agttatcggt taataagagg gcttatgcta gttagttaaa atcgggtaac tagtcattaa
    20941 atgctgataa ataagcaatt tttacgaaaa aaaaagaaaa aaatttgagg gaaaatacct
    21001 ttcaatctac aaaaatttat gttattatga taacataaag atgtaaatat cgaagcgtct
    21061 tttctgtatt ccgatcattg acaagtgaac agagaaaagt ttgcgatgat ataattatct
    21121 tgtgaaaaat aatcgaaagg aaggatttat aatatgtttg attctattaa gaatttggtt
    21181 tccggaatga cgccagaaat gaaaacgttg gttcaagcta ttctatattt aatggctaca
    21241 ttttttgcat tgaaaccagg attcactgct atgaaacatt tcggtgatgc aaaatgggga
    21301 gaaggcttaa aatatgttgg agccgttgtt gctattttta ttatccctgt aattacaact
    21361 gttatgttgt taacgatggg tactaaaaca ggtaatgact taaaccaaaa agctaatatg
    21421 atctcagctc ttattcctgt ggttggtatt tatctagtta caaagtttcc aaaagaagaa
    21481 caattaggtt aaaaggtaaa ttgagcaaat ttggaggata tgccgatttg ttcaatttac
    21541 tttttgctaa aaaactacac tcgaagcgta gtttttgaag tgagggaaga caatagatgt
    21601 aagatggaca gagaaaagat gttagttcac gcaaacgaag tattgacgag cggttttaaa
    21661 ggtaccgatt tggcgaagat aatgaatatg aacgtaaacc agttctatga ttatcgaaac
    21721 ggcaataaaa agattgaaaa agccagactt gaaacgctca tcaaatttga aaaagcgtat
    21781 ctatacgtgt tagacaaaca gaaaagaact attgaccgaa aaaaaggagt tttacaataa
    21841 tggcaaaatt caaagatatt accgaatcta ttaattatgt agcagaaaca gttcccgtag
    21901 ttgtactctc tttgaagcca caattactcg aagtgtacca aaaagaagaa aaagaagcga
    21961 aggcaaaaaa agctaaagca aaggtatgga aagaattcga tgcgttgctg accaaagatt
    22021 taccaaagaa gaattacgtg gtgattgagg acgtacaaaa gctcagcagt gaggaatttc
    22081 cggatgagga agatgcgatt ctagattccg aaaagtacgt tgttttatta aaatcaagtc
    22141 tgaattatgt tgttgattta ccggaaaaat tcaaagaaaa gctattagct ggtgtccgct
    22201 ttatggatag taatggtcaa ttattagtta ttcctgatga tcctaatatg tttgaaagag
    22261 aagttgaaga agctacagac ttctacagtg cagtagatca attagaggta gctactaaag
    22321 gcttagaaag aattgctgag accttcaact cttctgatgc ggttgaattt gaagctgtag
    22381 cagaagccga aacagaagcc gtaccagatg aagaagaagc tctttttgag gataatgacg
    22441 aagcaactga agcaggaaac caagaagcaa gcatagaaga aacacaaaca gaaacctacc
    22501 aacaaccaaa aattgatgaa aaacccgaat cccagagtga taaagaaaat tatgtttatg
    22561 aagctgaaaa aatcgtatct gaaagtgatg taccgaaaaa tttagatgct gatttgttag
    22621 aaaaagattt tgaacagatc atagccaata aatttcaacc tgtagtttta gatgaggtta
    22681 gtgatcctgt tgatttgaac gaagagatgc gatccattgc agagttaaaa ccattgctgt
    22741 ttttagctaa agagagcatg aacgctcgta tctctattgc taataataaa atcaacagtg
    22801 aattaaataa aacgaaagag caattgctac tcaaaggaaa gcaaatgtta gcggatgagc
    22861 ttttgcggat agaggaagca acatcactaa gtggtcaaaa tcagtttaca aatacgctat
    22921 cggtcgctaa agaaagctac gaagcagaag catctaaaat tgatgattta gtgatggaaa
    22981 aatccagtat cattcgtaaa gattatgata tggcgaaaca ggcttatttg gaagcagaac
    23041 taaagaaact agagcaacgg tacgatgctg aacatctgcc agaagttaaa caacaagaag
    23101 atgaatttag aaaagcaact gaagaaagtc ttgatcaaca ataccaagaa gcaattgaat
    23161 ctattaaaaa cgatgctttg aaacaaaatc aagaagcaaa agaagttgtg gtggaacgga
    23221 tcatcaattc attgaaaccg gaaattgaaa aatctttaac agaagtgcaa gaaaaaacgt
    23281 tagagattgt cgaaaaaaca aaggcagaaa atgaagctga gttccacgat acaaaagaga
    23341 aaacaacaga tgtggttgtc aaatattttg cgaacaaaga agaagttgaa aagctagtag
    23401 ctaaagatac gaatgagtta gaatccaaac ttgttgcaca gcaaaacatt attgaagatt
    23461 ataaaaatcg agtaaaagag ttcaaggatt tagcagatgg ctataaatta aatagccaaa
    23521 aattgactga acaaagtgaa gctttacgag aagatttatc tcgtgcaaga aacgacctat
    23581 cacaaatggc ggaaaaaaca aagtcactag tagttactac agaaaatcaa actgagtcta
    23641 aacgtgattt tacaagcaaa aagatggcga ctatcatcgc tgtatcagca atggcttgtg
    23701 gaacgatttt gggctcatcc tacttcatta gtcataatca ccaagaagcc caagctcaaa
    23761 cagaaacctc aatttcaaga gtggaaaatt cactaggagc aaagacagct tctacttcaa
    23821 caacagacaa caactatgaa gcaacaccaa cgacagaatt taaagtcgga gaagatgttg
    23881 tcatcagtat tgatgggaaa actactaagg ctgaagtact ttccattgac ggtgataagg
    23941 cagttgtgaa agctccagat gggaatcaat acaaaataca agctcactta actgaaaaga
    24001 attaaggagg gctaaaatgc gagaagaaaa tattgtttat ccagtaattg aaaatcaatc
    24061 aaatacaaaa tcttctcaac ttcttcaaga agtgcaagtc gtttatccgg ttaatgaact
    24121 accacaaacg aatgaaacag tgagcaagtc aatatcatta attggcttgc ttattgttgc
    24181 aacggcgcta actgttggtg tttatcgtaa gctgaaagtg aaaggaagta tttctgatgg
    24241 cagataactc aaactatgga tttaaacata atttgcatca aaaaccttct gaaacaatag
    24301 tcagagttga ttggcttgaa aaacatgtca acagcaccta ttctgttaca gcaaaaagac
    24361 taattgtttc agctattgtt gttgcagttg ttgttcttgg ttcaatcgtt tatttggttt
    24421 ccgatacgat taaattgaga tttattttta ttccaacgct attgatgata attggttttc
    24481 ttatactgat tagtcagtat atgtttattg atccatctag cggatcactg atctcaggct
    24541 ctattagact gtttaaatca gtagttaaca cagcaagagt aacgatgggg aaaaagaaac
    24601 catttcgagg aacggagatt ttgaaagtta gacaagatgg aacgattatg tatcgagatg
    24661 gtagtgtagc actaatgttt aatttggatg gtgctacctc gttaaccgcc ttcccagaag
    24721 aaatcatagc gcaagaaggc aaatcaattc aataccaaaa tgcaagggat cgttccttgg
    24781 ctgaaatcaa aattacttca tcacaacctc agaatacgga acgtcaaata cggaacatga
    24841 aagtacaaaa aagaaatgca aagagcaaca aagctgtgtt tgacatagta gatcaacaag
    24901 agaggtttgt atctgaatat attgatgggg tcaaaactac ggtgatccaa tatcttattt
    24961 tgaagtcaca atctcagatg gtattggatg aaggcgtaga acgtttagaa aattacacga
    25021 gtagagggct ttactatagc gttactcagt tgtcagctaa acaaaccaaa gaaatattat
    25081 cagaaattta tgcactgaaa taatagaggt gagaaattta atggaactaa tgagtagatc
    25141 gaagctactt aatttcagaa aaaagaaaca caaaaaagag caaaatgctg atagttctaa
    25201 agcggtgaat aatacttatg tcagtgattt aacatcattg gttggttatc aatttacacc
    25261 atcttacatt aggacaggta atcggtgggg aacgattgtt aaattagtga atacgtatgg
    25321 aatgaacaga aattatgaat ttggatggat ggttaaagct attcctgaag tgaaggttga
    25381 aggagtaaaa gcttacttaa tcgaagcgga taagccagtt tcgcaaaaag atcagcaaga
    25441 aatcatgcac gaaaatgtcg gtggatcaac gaacagttat gaaaataact tgaacgataa
    25501 aaattcagat gcagaaatca ataaaactgt tatgcgaatc attgatttga atacagcatc
    25561 tctgcttgac agtacggcaa acaaaattat tgattggaag ttagaaatcc tcttagtatc
    25621 cgattctcct aacaagatca gcgaacagtt gatcaaactg caacgcctgt atgatgaaaa
    25681 aatgtatgga ttaaaactta tgtcttttgg tggcgatcaa cgtgatctgt ttgataggct
    25741 tttaagtgag ccagtcggta gtgtttacga atacacatct atgagttctg attttgcagg
    25801 aaatgatcac gctatccgta aaggcttaga tgatgcagac ggatgggcta tcggaacgat
    25861 gtctacaagc tacgcttcag gtgtagcgtt tatggcaatg gatcgttctt ttaagggtaa
    25921 agtcttagta gcatcccaca aagatgcaac aatcaaaggc tatagcgaag aaatctcagc
    25981 atcatcactt tgggggcaat tgattgctaa taacgcaatg gcaaatcata aacggacgtt
    26041 tcacatcgta ttaaataaat ttgactactt tggtgatccg acaggggaaa catttgttgc
    26101 taagccatct ttaaatagtg tgatagagaa gattaatcta gctgaagaag gacttaattc
    26161 tttagagctt tttggtgatc gaaaggatat tggagattta tatagacgta atcttgataa
    26221 actaactcag attttctatc tgttagcgga cagagaatta aatcctgcaa caagagtatt
    26281 gctgaagaaa gagttgggga acttttatat tagtcagaag ctttgggata ttaactatga
    26341 agagcggtcg aaactgttag taaacagcag tgatacaatg ccggttcttg gggatttcat
    26401 cagctattta acaaatgctg agacaaaagc gaaaaaatcc ggtacagaaa aagaaattga
    26461 tcggattatt gtattaaaag atacattgcg aacagcattg gatagcttct ctaagatgtt
    26521 caatcagaga actacattga aagaaattgg caagagcgac aaattgcagt tttactacaa
    26581 tttgagcgat ttaagaacag aaatcaatgt catggaagcc caatttttaa atacctttga
    26641 cttcatcacg tcacaagcta aaaaaggcga tatcgttatg atccatgggt ttgatagatt
    26701 atcagttgaa accgttggat taattaaaaa gcgactaaca atgcttgaag aagatggagt
    26761 ccggcttgcg tttctctttg atactatcgg atcaggagaa tctaaagacg gtatcgaaac
    26821 agctgatatt ttcaatacag atggaaaaat ttatcaaagt tttgaaagtg attttaacta
    26881 caccatcatc gggaaaatga ccagtgaaga attgatgaag tatgaaaaga aggttgctcc
    26941 tgcaagaaaa ggagaagatg atcaaaaact atcagtggat ttgagacagt atttgacatc
    27001 aggtcgaagc aataaatttc aaatcagaag accagcggat ttgactaata attttgttat
    27061 tggagagttt attatttaag tcttatcctt gtttttgaat gtttaaggat aagaaacaat
    27121 atttatatac atgactgaga gaaagaatta tagtggcggt aaaataatga aatcaaatat
    27181 aaaaataata gcaggtgata aaatgaagga aaaagaaaat ttagtttggt attttaacag
    27241 aaatccgcat atgctgatta caggaagaac agctacagga aaaacttatc tgttgaaaag
    27301 aatggctgac tatttatcgc aagttggtat tgtttctgct tcttttgaca aaactgaatt
    27361 tgaagaaatt ttatcttcgt ctcgaaagga aatggaagat cggtttgagt atattaaaga
    27421 aaatcgtttt aaaatgtttg acgtaagtta ctctgattta gacatgaagc cttattttgt
    27481 tctgatagat gagctagatt caaggttgtt actcttagaa aaagaaaatc cattggctta
    27541 taattaccta ttactaataa taaaggatat tgtgttaaaa ggacgagtag taggtgtttt
    27601 ttttattgcc gttcgtcaag gaaagcaacc attgttagaa tctatagaag ataatatgtt
    27661 aacacgtatt tttttagggg attccaaagg aaatggaacg atttgttttg atggaaatac
    27721 aaagaaattc caaacagagc tagtaacaga agatttcttt tctgtagact gttagtatag
    27781 cggaggttaa ataatgaaac caaacataaa aattttagat cgaatatttc taggtaaaga
    27841 cacagaagta atcctaattc aacatgaa
//
LOCUS       DAZKNV010000035        26453 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000035 DAZKNV010000000
VERSION     DAZKNV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.035"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..634)
                     /locus_tag="ACG8M1_001687"
     CDS             complement(38..634)
                     /locus_tag="ACG8M1_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0422402.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            984..1328
                     /locus_tag="ACG8M1_001688"
     CDS             984..1328
                     /locus_tag="ACG8M1_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFQ0422403.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            1329..1748
                     /locus_tag="ACG8M1_001689"
     CDS             1329..1748
                     /locus_tag="ACG8M1_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFQ0422404.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1840..2190)
                     /locus_tag="ACG8M1_001690"
     CDS             complement(1840..2190)
                     /locus_tag="ACG8M1_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422405.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(2156..3487)
                     /locus_tag="ACG8M1_001691"
     CDS             complement(2156..3487)
                     /locus_tag="ACG8M1_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFQ0422406.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3742..4308
                     /locus_tag="ACG8M1_001692"
     CDS             3742..4308
                     /locus_tag="ACG8M1_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0422407.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            4453..4540
                     /locus_tag="ACG8M1_001693"
     tRNA            4453..4540
                     /locus_tag="ACG8M1_001693"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4485..4487,aa:Ser,seq:cga)
     gene            4876..5850
                     /gene="bsh"
                     /locus_tag="ACG8M1_001694"
     CDS             4876..5850
                     /gene="bsh"
                     /locus_tag="ACG8M1_001694"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFQ0422408.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            6175..8070
                     /gene="asnB"
                     /locus_tag="ACG8M1_001695"
     CDS             6175..8070
                     /gene="asnB"
                     /locus_tag="ACG8M1_001695"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFQ0422409.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(8265..8711)
                     /locus_tag="ACG8M1_001696"
     CDS             complement(8265..8711)
                     /locus_tag="ACG8M1_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFQ0422410.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8939..9088
                     /gene="rpmG"
                     /locus_tag="ACG8M1_001697"
     CDS             8939..9088
                     /gene="rpmG"
                     /locus_tag="ACG8M1_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0422411.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            9176..9694
                     /locus_tag="ACG8M1_001698"
     CDS             9176..9694
                     /locus_tag="ACG8M1_001698"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFQ0422412.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(9771..10727)
                     /locus_tag="ACG8M1_001699"
     CDS             complement(9771..10727)
                     /locus_tag="ACG8M1_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422413.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10893..11699
                     /locus_tag="ACG8M1_001700"
     CDS             10893..11699
                     /locus_tag="ACG8M1_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422414.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            11696..12685
                     /locus_tag="ACG8M1_001701"
     CDS             11696..12685
                     /locus_tag="ACG8M1_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFQ0422415.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            12682..13686
                     /locus_tag="ACG8M1_001702"
     CDS             12682..13686
                     /locus_tag="ACG8M1_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFQ0422416.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13818..14360
                     /locus_tag="ACG8M1_001703"
     CDS             13818..14360
                     /locus_tag="ACG8M1_001703"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFQ0422417.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            14380..15078
                     /locus_tag="ACG8M1_001704"
     CDS             14380..15078
                     /locus_tag="ACG8M1_001704"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFQ0422418.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            15099..15311
                     /locus_tag="ACG8M1_001705"
     CDS             15099..15311
                     /locus_tag="ACG8M1_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFQ0422419.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            15311..16273
                     /locus_tag="ACG8M1_001706"
     CDS             15311..16273
                     /locus_tag="ACG8M1_001706"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFQ0422420.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            16291..16686
                     /locus_tag="ACG8M1_001707"
     CDS             16291..16686
                     /locus_tag="ACG8M1_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0422421.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16849..17214
                     /locus_tag="ACG8M1_001708"
     CDS             16849..17214
                     /locus_tag="ACG8M1_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFQ0422422.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            17211..19022
                     /locus_tag="ACG8M1_001709"
     CDS             17211..19022
                     /locus_tag="ACG8M1_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFQ0422423.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(19084..19251)
                     /locus_tag="ACG8M1_001710"
     CDS             complement(19084..19251)
                     /locus_tag="ACG8M1_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFQ0422424.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            19500..20489
                     /gene="galE"
                     /locus_tag="ACG8M1_001711"
     CDS             19500..20489
                     /gene="galE"
                     /locus_tag="ACG8M1_001711"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFQ0422425.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20501..21985
                     /gene="galT"
                     /locus_tag="ACG8M1_001712"
     CDS             20501..21985
                     /gene="galT"
                     /locus_tag="ACG8M1_001712"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFQ0422426.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            22009..22989
                     /locus_tag="ACG8M1_001713"
     CDS             22009..22989
                     /locus_tag="ACG8M1_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0422427.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            23180..23902
                     /gene="tsaB"
                     /locus_tag="ACG8M1_001714"
     CDS             23180..23902
                     /gene="tsaB"
                     /locus_tag="ACG8M1_001714"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFQ0422428.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23886..24428
                     /gene="rimI"
                     /locus_tag="ACG8M1_001715"
     CDS             23886..24428
                     /gene="rimI"
                     /locus_tag="ACG8M1_001715"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFQ0422429.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            24435..24899
                     /gene="rimI"
                     /locus_tag="ACG8M1_001716"
     CDS             24435..24899
                     /gene="rimI"
                     /locus_tag="ACG8M1_001716"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFQ0422430.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24896..25912
                     /gene="tsaD"
                     /locus_tag="ACG8M1_001717"
     CDS             24896..25912
                     /gene="tsaD"
                     /locus_tag="ACG8M1_001717"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFQ0422431.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
BASE COUNT         8622 a         4549 c         5491 g         7791 t
ORIGIN      
        1 acattgtcaa tcaatgacta attttacaaa ataaatatta tccaagaaga ccacttagat
       61 attgacctcc ataaatcaag gccatactat ataagaaaat cgacagtggt ttagcaatca
      121 aaatgattag tgtatatcgt ttcactgaca tgtttgtcaa tccagccatc aaacataacg
      181 catcgtcagg agcaactgga agaaaaatag ctagagcaaa cagcttctca aaacggtttt
      241 gattatccag ccagccaata tatttgttat atgtcttatc gctaatcatg gaaagtatga
      301 atggctttcc ataacgacgc cctagcagaa aaatgataat cgaaccaatg cagattccaa
      361 tatagttata gataaatcca gcataagggc caaatatcag gacaccagct gcagtactga
      421 tccctccagg aatgattgga ataactactt gcaggatttg gatgaagaca aaaataatcg
      481 gtcctaaaat gatggaatca cctactaatc ctcttaacgc attcaaatct ttgaaaacac
      541 ctaaattaat aaaataaatc gtcagcgcga ttgataggcc taatccgata atggatatga
      601 aatttatcag ttttcgagag gcagcaatat tcattattca tcaactcctt agaggttctt
      661 tgttaactat actttactag aaaagcaact aactgcgcca ttttttgata tgacagaaaa
      721 caaacaattt tgtaagttca tcataagtat aaaagattga tctcaaaaaa acatccaact
      781 aaagacttat ttaataactt gtttttttta aaataaaaaa agcgttagca actatgctta
      841 aaaagcatat cgactgaata aactaagcat tggacaggct gaaagactac atttaaaatg
      901 aaatgcgaag aaacaataga aaataaagtt gccttagaac catagttgaa tcacctaaca
      961 gtcgtgaagg gagaataaga gaaatggcag aaaaacaaac cgcaggacga gatcaattag
     1021 gagattttgc accaaaattt gcagaattaa atgatgatgt tttatttgga caagtatggt
     1081 ccagagaaga attatctgct catcagcgta gtatcatcac catatctgca ttaatttcag
     1141 gaggaaattt tgaacaattg ccagctcatc tgaagattgg caagcaaaat ggcattacta
     1201 gtgaagaaat agcagaaatc attacccatt tagcttttta tgtagaatgg ccaaaagctt
     1261 ggtcagcttt tagtttagca aaagaaatct atttagaaga aaatagcgaa gataagaaag
     1321 aggcgtaaat gatgacaaaa cacgaagaaa tacacaatgg cgtgattttt ccagcaggtg
     1381 aaaaaaacga agcttacgct caagtattta ccgggcaaag ctatctgaat atgttagtga
     1441 atgatcccga agtttctgtt ggtgtaggta atgtaacttt tgaaccaggt tgtcgcaatc
     1501 actggcatgt ccatacagac ggctatcaaa tcttacttgt gaccggagga gaaggctggt
     1561 atcaggaaga aggaaagcca gcaagacgat taatggctgg agatgtcgtc gtaacgcaca
     1621 aagggattaa acattggcat ggtgcgacaa aagacagttg gtttgaacat ttggcgatca
     1681 ctgctggtaa ttcagagttt ttagaacctg taacagatga agtgtatgaa ggattggaaa
     1741 atcaataatg tcaagcttga acagctcctg aaagtagatt ttaatcgaac tttcaggagc
     1801 tgcttttttg attcagtctt ttataaatag aaaatagggt taataatagg aatgagaagc
     1861 acgtcgaaag atcttaatat tgataatcgg ctgggcatac atgatttcca cgtcatcaat
     1921 caaactacct aacagatgat aatcttcccg atcatgtcgg ggattaccta atagttcttg
     1981 atagtagatt tccatactag ggtcccgagg attgttcagc aaatcagcaa gtacatctaa
     2041 atcttctggc tgagtttctg ccgtaccctg tatctctatg aaaagccctt cctcagcaaa
     2101 ttctactcca atacgtattt cagttatttc atgggaatat aaataagtaa gaagctcatc
     2161 gatgattctt tttgataatt ctttttccaa gtgtcttttt ttcctttctg acagcggtaa
     2221 agttatctag tatcggtaca aggatacctg caacgaaacc agttgaaaaa ccactgttat
     2281 atagatttag tcctccgtgc aaagtgctga cgttatggac aagagcaata tgtagcacac
     2341 cagctattac accgtaaaaa ctgccgtaaa aaccgcttat gggcgcaaga cctgtcccaa
     2401 acacagctgc aacaagcatg ccagtactgg tgatctcatg aaaagttcca aacaaagaag
     2461 caataaatat tccgactagt atcggaaaac tgttttttaa atgacaacca aaagcactga
     2521 aacccaccgc agataaaata gcaccgatga caggtccatt taactgaccg ccaaccagca
     2581 aaacataaga agacagcatc agaccaacta agcccatgtt gatcaaagta gcaccaatac
     2641 cagaattagc aatgaaatca gttgtcaatt ttccagatga atcgaaaatt tctcgaatcc
     2701 ccgaaagccg aaaggaatta taatagaaac caattccgac tgtcagcgaa aaaaagccaa
     2761 aaataatcca aatgagagga aagtgatatt cattgaaaac caatgtattt tcgacgattg
     2821 aatagctgaa taacctcaaa acagcagtaa aagtcatcgc aatcaaccca gaggtgaatc
     2881 caatattata aagtgtgaat ccacgatgga aaactaaagt ttgagcagct aagggcggaa
     2941 gaagtatacc aattgctatg ccagctaaat tccccaataa aatacctatc agtaaaggaa
     3001 aacgcatacc aaaagtgata taactaacga ccggtgataa tacgctacca aacagtccga
     3061 tcatgatgta ctgagaaaaa ggtttattga caaatacagc gtatagatac acacctaaaa
     3121 tgattgagat agaattataa aggtttttgc caaaaaaaga gaaaccggta actgttagaa
     3181 tcgaagcaaa taagggaccg tttaaaatca ccttgtgccg ataagctaaa agcacagaaa
     3241 gtaaggtcaa aatccctaca tttatgaatg cgcttccgaa aacacctaaa gcaaaataat
     3301 ctgtcaaaag attgcttggc gaggtaagaa tagttagcaa tccactccaa ttatcagtag
     3361 gagtattaga aagcaagcca ataaaaagaa aaaaaacacc tgtaaaacca agataaaaat
     3421 actttctttt ctgtgaaacg attcgttttt gaggatgaat ataaataacg tcagtttcgt
     3481 tttccattac acaccttctt tttcattttc tttaactata acttgaaatg aaagatttgg
     3541 acaactatca tttaggtcaa aactaaaaat gtaagggaac ccattgaatt taaccaaatt
     3601 tttttaattt tgcaaaaaaa agttaaagaa gactgaaaaa aatttaaaat ataacgtttt
     3661 gagtaaaatg tttgcaaaaa atgctaaaaa tagggtacaa taaaacaaca tatactgcag
     3721 taaagaagtg ggggagtttt aatgagaaga aaagtctata ccaaggatca aattctaaaa
     3781 gctgcttatg atgttgttgc aaaggaaggg tttaaaggat ttactgcgag aaatattgct
     3841 aaaaagatgg ggatttcgac acagccgatt tatctggaat tcaaaaacat ggaagattta
     3901 aaaaatacgt tgctggattc tatctttgaa caactaaaag aagatgtttt ccctattgaa
     3961 cgtactggtg ataaaatcat tgatctcggt ttgaactata tctactttgc aaaaaagcat
     4021 catagtcttt acatggcatt gtacattgat gaacatgggg acggaaagaa aatgcatgat
     4081 ttttcataca attatttccg tgaaatagtt aaagaagatg aaagatacaa tcaattatcg
     4141 gatgaatatg tcgatgctct gcatactggt acatgggtag cagtgactgg cttagcgtca
     4201 ttgatgtcat caaacatcat gcatccaaca gaagaacaaa tcattgcact gatcaaacgg
     4261 acaattgact cgattttagc attagataat cctgaaataa tcagatagtg ttctatcagt
     4321 atgaatttga tcggtaagtc cgttggctgc aaactgtcaa tggacttttt tgctaaaaaa
     4381 agcgatttct gttatttatc tattagaaat aggcttgaca tttcgtgaaa aaagtttaaa
     4441 aatagtactt acggaaggtt ggcagagtgg taatgcaccg gactcgaaat ccggcgaacc
     4501 ggctaatacc ggcgcgcagg ttcaaatcct gtaccttcct tatatcaacg attagaggtt
     4561 gtgaagaagc tgtcctgcat caagtaataa gaacggccaa acaaaaatag cttttcctat
     4621 tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttgttcgga
     4681 ataaggggct gtgacaagac ttttgtcaca gccccttatt gttgtacttt taacctacaa
     4741 tattttttga ttccccctga gtactatttt ttataaatgc tagtaaatca atcttctttg
     4801 gccttttttt tgataaaaaa aaatactaga tgtaagataa aagtgtaaaa acgatttgtt
     4861 ttaggaggga aaacgatgtg taccgcaatc acttatgcaa cgaaagacca ttattttgga
     4921 aggaattttg attatgagat gtcttataat gaagtagtca ctattactcc aagaaattat
     4981 cgtttcgatt ttagaaaggt aaaaaattta gataaacatt atgcaatgat aggaatagca
     5041 gctggggtat ccaactatcc actctattat gaggctacaa atgaaaaagg gttgagtatg
     5101 gcaggactga attttcctgg caatgctgat tataaagaat tacaagaagg aaaagataac
     5161 gttgcaccat ttgagtttat tccatggata ctagggcaat gctcaaccat agacgaagct
     5221 aaagaattat tggctactat caatctagtc aatatcgatt ttagtgaaaa actacccttg
     5281 tcacctttac actggttatt agctgataaa gaaaaatcga tagtaattga aagtatgaaa
     5341 gatggacttc atttatatga taatcctgtc ggtgtgttga caaataatcc gccatttgat
     5401 tatcaattat ttaatctgaa caattatcgc tcgctatcaa atggaacacc agaaaatcat
     5461 ttttcaaacc agatcagctt gaatgtttat agtcgtggga tgggaggatt gggcttacct
     5521 ggagatctct cttctgtttc tcgatttgta aaagccacat ttactaaaat gaatgctgca
     5581 tcaggtgatt cagaatctga aagtatcagt caattttttc atatactagg ctcagtcgag
     5641 caacaaaaag gagtatgcga tactggagaa ggaaaatacg aatatacgat ttattcttct
     5701 tgctgtaacg ttgataaagg gatttattat tatcgtacgt atgaagacag tcaaattact
     5761 gctgtaaata taaataaaga agacttggat cgtcatgaat tggtcagtta tccagtcata
     5821 aaagagcaac agataaacta tgtcaattaa ttaatgaata gatccgtttg gtatcatatt
     5881 ttctgataca gtcataatta gacacgatct ttaggtcgtg tctttttttg ctgttttttt
     5941 tggaaatagc atccactaat atttttttaa cacgaagaga ataaggtagc ctcaaaaaag
     6001 aaaacatggt aaattagata ttgggacttt attttctgta aaaacagaaa ctttcatctt
     6061 ttgttttcac gtgacgaaat tgtaagagag aaaatattcg tccgctattt attctatgat
     6121 aagatgcata tgaatgaaat aaacagtaat tttatattag gatgtgaaag ttaaatgtgc
     6181 ggtattgtag gttttgttaa cgacaaggac aacaaaaaaa caattattaa tacaatgatg
     6241 gatcgaatcg ttcaccgtgg acctaatagt tcaggagaat atatcgataa acatgttgct
     6301 ttaggattca gaagattaag tattattgac ttagagggcg gtactcagcc tatttacaat
     6361 gaagatcgga caaagatcat tatttttaat ggcgaaatct ataattacca gcctttgaga
     6421 gaagaattga ttgcagctgg ccacgttttt caaacacatg cagatacaga agtccttttg
     6481 catggttacg aagaatgggg aacagaatta ttgcaaaaga tccgcggaat gtttgctttt
     6541 gctatttggg ataatgaaaa gaatgagtta ttcggtgcaa gagaccactt tgggatcaaa
     6601 ccatattatt atgcagaaat gaacggaaca tttatgtttg gttcagaaat caaaagtttt
     6661 ctgcctcatc ctgattttaa caaagaattg aacaaagaag cgttgaaacc ttatatgact
     6721 ttccaatatt ctccattaaa cggcgaaaca ttcttcaaag atgtctatcg tttgcctgaa
     6781 ggccattatt atacgtataa agatggaaaa ctagacattc agcaatattg ggatgcagat
     6841 tttgaaacaa aagaaacgca ttcccgacaa gaatggatcg aaaaaatcga cgaaaccgtt
     6901 caagcttcta ttgaagcaca tacggtcagt gatgtagaag ttggttcttt cttatccagc
     6961 ggggttgatt ccagttatgt aacctctgta ttgaaaccag atcattcttt ctcaatcggg
     7021 tttgatgata aaacctataa tgaagcgatt gaagccagaa aactaaccga actattggac
     7081 ttagataata cagcagcagt gatcgacgga gacatgtcgt tcaaagcatt ccctttgatc
     7141 cagtatcact tagatgaacc tgattcaaat ccttcttgcg tacctttgta ctttttagca
     7201 aatcttgctt cacaaagtgt gcgggtagtc caatctggag aaggggcgga tgaactgttt
     7261 gcgggatacc aaacgtatgg attccatacg aattcaaaat tcatccgtgt gattgctcaa
     7321 ggattgaaaa aattaccaaa aggaacacgc tataatttag gacgtaaaat cggaaaaatg
     7381 aaaaatttcc atggacggat ccatttatat gaatcacttg ctcctgcaaa agaatatttt
     7441 atcggtcatg ctcgagtgtt cgaagaatca gaagcatcag aagtgttaac accaaaatat
     7501 caaacagcac catctgtgga tgaaatcatg actgttcatt acgagaaaac agaaggaatc
     7561 aaagatgaag tcaataagat gcaatatgtc gatcttcatc aatggatgcc aaaagatatc
     7621 ttgttaaagg cagataaact ttctatggca agttctttgg aagtccgagt acctttattg
     7681 gatatcgaag tcatgaaatt ggctcaacaa ataccaagta agtttttatt gaatcaaaac
     7741 aacacaaaag atattttcag acaagctgcg aacaaacatc ttccggaaga atggtcgaat
     7801 cgtgtgaaat taggattccc tgtgccaatc aaagcttggt tgaaagaaga acacggctac
     7861 gaacaagtca aagcattatt cgaagcagat tttgcaaaag aattttttga tcaagaaaaa
     7921 atcatgaagt tgctagatga ccatcacgaa ggacgtaaag aagagcaaag aaaaatctgg
     7981 acaatcttca gtttcttgac atggtataaa gtctactttg tagatgaaac gattccgcaa
     8041 gcagaagcaa tcgactatgt gactgtttga tgaaaatcaa atatcaataa aaaagaggtt
     8101 ttctcctacc gtttaacact gagtgataag aaacaatttc aaaaaacagc tcttcccgtt
     8161 ttatagatat tatgacttat ggttcggagt tggcagagga acaccattgt ttcgaacata
     8221 agggggttgt gacacgattt tcgtcacaac ccctttacat atgttcaata atcgatttct
     8281 ttttcttttg tcccatcttt tttataaatg aacaaagttg attctttgtt ttgtgctact
     8341 tgctttcctt tttcgattgc ttcttttttt gtatcaaaat ggttgcttgc cttttttgcc
     8401 cctttagatt tcacgatcca ttgttcttcc tcatattcta cgatcacatc tgaatcaagc
     8461 agttttccag cacgaggatt cgtatcgtgt tcatccgtct tgcttggatt tttttctttt
     8521 tcgaaagttc gtttttctga ttcactagca tcttcatacc atttttttgc ttgatcaatg
     8581 gcaattggga tcgcacggtt atcagggtac ccttcatcta ataatgcatt tgcgatgtcg
     8641 attgcttttt ttcttgtcaa tttatctaag tttttcattg atgcaggaaa gtccttcatg
     8701 ttccatggca tattagtatc cccctttatt aaaaaacata atctatataa acaagtgtaa
     8761 gggtatttat acaaaaagaa aaagattttg tttgagaagt aaaaccgttg tatttatcgt
     8821 caagtagttt tacttaacaa aatcgtgaaa aacactagca atctagaaaa aatcatggta
     8881 agataatcaa gtctgagagt catcttagag gattcttgta aaaatgggag ggaaaaacat
     8941 gcgcgtaaac atcactttag agtgtacttc ttgtaaagaa cgtaactatc taacaagcaa
     9001 aaacaaacgt aacaatcctg atcgtttgga aaaacaaaaa tattgcccac gcgaacgcaa
     9061 agttactttg caccgtgaaa caaaataatg tttttaaagt tctcaattcc ttgctggtca
     9121 aagaattgag acttttttta tctcaaaaca tctaaaatca taaggagcgg ataatatgtt
     9181 tatttccatg tgggcacaag ataaaaatgg tctgatcggc aaaaatggtt tgttaccatg
     9241 gcgattgcca aatgatatgc gtttctttcg cgaacataca atggatcgaa ttttagtgat
     9301 gggaagaaag acctatgaag gaatggggga tctttcactt ccttatcgcc atatcatcgt
     9361 gttgacaacg caaccaaatt ttcgcacgaa agaaaatgcg gaagtaatgc attcgatcga
     9421 tgaacttttg tcgtatagtc aaacgatctc agaagatatc tatgtttcgg gtggtagtcg
     9481 gatttttcaa gaacttcttc cttacactgg tcggatctgg cgaacattga tcgatagcac
     9541 gtttgaaggc gatacgtata ttgggaatat tgatttttca gacttcgccc ttatagagga
     9601 gtatgagggg ataacggatc aagaaaatct atatgcccat cgttttcaaa aatgggaaag
     9661 agtaaaaaat agggttgctt caaaagaaga ataaaatcta tgcgtctagt ttgttaataa
     9721 gaaaaaaagc atctcacgac taatcgtgaa gattcttttt ttagttaaaa tcaatttagt
     9781 ttttctttga tatcattgac catttcctga ctggcaatag gtccgttata tagccaacta
     9841 gattcaggtc cgaattgcag tacatgattg tctgtcactg ctttaagatt cttccagctt
     9901 ggttcattga acatggcagc atctttgtca ctgttcacaa ggatgatgta gtcagcatct
     9961 aattcagcta gcttttcaga ggaaacagca gaccagtcag aagtggcttt tttggagacc
    10021 tcttccacta gatcaggaac accaaattcc agatcgtcgt atacgattct tccacttgac
    10081 cgatttttgc tgaccataaa ggctgagttg ttggtcaccc acaacactgc agctgtcttg
    10141 ttctcgattt tatctgctag ttcttctcga gttttcttga tggatttttg ataatcggaa
    10201 atgatttttt ctgcctcttt ttcttttgcc aaagctttgc cgacatcttt tagttgttct
    10261 tcccatgtga catctgttcc gttttttaca acataagttg gcgcgatttt gctatattgt
    10321 tcgtatttcc cgccttcgac agtagcggaa gaagaaatca acagcaaatc aggctcaaag
    10381 cttaacactt tctcataagg aaggtcataa gaaatcgttg ggacatcctt taaatcatct
    10441 tgcagataat cttgaatgga accactgcca acagtccact gggcgatagg tttttcccct
    10501 agtgcaatca gatagtcttc taagtaactg ccgatgatcc gtttgggcgc gtttggaatc
    10561 tctactttat gtccaagtgt atctgtgact gtatgagtac tattggatga agtcgtcgaa
    10621 ttggcagttg tagctgtttc tttatctgaa gagggggagc aagcgctcag tactccagcc
    10681 agcagcaata tgctagataa tgtgaatact tttgttttta atttcatttc tttcctccta
    10741 acataattga gaatctttct cattggttat tattcctgat atttcgaacg ctgtcaaccg
    10801 cttcatttgg ctatagatat gaaagtagcg cttgacgaaa tgttgaaaca gcgtcataat
    10861 tgagaatgat tttcagcgaa aggatgggtg aaatgacgag attaagagca gctgacattg
    10921 cagccggcta cgaaaacaaa aaaatcattg aaaacatgtc tgttacgatt cctgaaggga
    10981 aaatcactag tttgattggg ccaaatggaa gtggaaaatc tactttattg aaaagtttta
    11041 cccgtatact acctgtgaaa tcaggaaaga tcattgtcaa taactctgat atctctacat
    11101 acagttcaaa agaacttgca aaaaaaatta cattattagc acaaactagt gaacacccta
    11161 caggtatgac agtagaagaa gtagtatctt acggacgata cccttatcaa aaactgttca
    11221 gtggcatgga cacgcaagat catgaagcaa tcgagtgggc gttggatgct acaggtctag
    11281 ctggatttcg tatgcgggat atcgcaacgc tgtctggtgg acaaacccag cgtgtctgga
    11341 tcgctatggc gcttgctcag gaaacagata tcttgatctt ggatgaaccg acaacatttt
    11401 tagatccggc acaccaatta gagatcctac agttattgac tgaaatcaat caaatgaaac
    11461 aaacaacgat cttgatgtcg attcatgaca ttaatcatgc ttcacgtttt tcagattatt
    11521 tattagcaat gaaaaacggt aagttgatca cagaaggtac acctgaagaa gtgatcacaa
    11581 aagagtgtat gaaaaaaata tttgagattg atgcaacgat tgtcacgctt ccaagaacaa
    11641 ataaaccagt ttttctaacc tatgatttgt tgccaaaaga gcaggaggat caattatgag
    11701 gactatgaag aaaaatagac tcctgctttt ggtctgtttt gttcttttga ttattttttt
    11761 tgttgctctt tcaaatggcg cagcgactgt gggaaaagca gatttttggc aggcgttgtt
    11821 tgattttgat agatcaaaac aaagtcacca aatcatacga aatattcgtt tgcctcgtgt
    11881 ggcgggagca tttcttgtag ggagttgttt tgcattgagc ggtgcattga tgcaaggagt
    11941 gacaagaaat cctttagcag attcaggctt actaggaatc aacgcgggtg cttcgttggc
    12001 aatggccctt agttttgctt tttggcctaa agcttctgat ttttctgtgt ttctaatgtc
    12061 attggcaggt tcttttgctg taactttgct cgtatttggt tttttgcagt tttcgaaaat
    12121 gggcatgaat cctttacagc tgattttagc tggcgtagct attagttctt tttttactgc
    12181 tatcagccaa gcacttaccc aattctttaa tctgcagcag gatcttgctt tttggtttgt
    12241 aggcggagct gccaatatca catggaaaca attagcagta ttgtttcctt tatatatact
    12301 tgctgttttg gtttcttttt cattaggaaa agcaatatct ttgattcatt tgagtgaaac
    12361 acatgcatta gctcttggaa gtcatcctaa acgaacgcgg ttgattgttt tctgtctagt
    12421 tgcagtgtta gcagccattg ccgtttcgtt agtcggacct gtttcattta ttgggctgtt
    12481 ggttccgcca gttgttcgcg gaatggttgg aacggactat cgttatgttc tacctgtctc
    12541 ttttttagtt ggcggtggat tggttatgtt ggcggatttt acagcgagga tgatcaatcc
    12601 cccttttgaa acaccttttg gattagtcat tgcattgatt ggcgttccgt ttttactgat
    12661 acaagtaagg agggaacaac ggtgaaaaaa atatattgga cgttctattt cttgcttttt
    12721 gtacttgtca tcctgtctat aggtagttta atgattggta cgccttttat ttacctggat
    12781 cagctttttg ccacgttcat agggaaagaa tcatcttctt tggcgctgat tgttagagaa
    12841 tttcgagttc ctcgattact gatcagttta ttagcaggag cttgtcttgg cgtttctggt
    12901 tatatcttgc aaggagtaac aagaaatgaa ttggcagatt ctagtatatt gggcattaat
    12961 gccggagcag gatttttagt gatgctttat ttaggtttct tttcgcacta ttcgctgccg
    13021 tttctattgc tagttgtagc ctttctaggt ggtgttttag ctgcttgctg tgtctatctt
    13081 gcggcctatg atcgaaatgg ctttttgggt atgaatcgaa tcttattgtc cggtattgcc
    13141 gttaatgccg gcctttctgc attaacattg ctatgcacga tccaattatc taaggaaaat
    13201 tatggatttg tgaatgcatg gttagcggga tcaatctggg gtgcgagctg gccttatgtt
    13261 tgggcattgc ttccatgggc ggttatctta attccgctag gaggacttta tgcacagagg
    13321 attggattgc tatcatttgg tcaagaacgc gcgcaaggat taggccttaa cgtggctaaa
    13381 agtcaaaaaa tccttttgtt gttagctgtt gctttggcaa gcggtagtgt agcggtgaca
    13441 ggtagtttat cttttgtagg actactagct cctcatgctg cgaagctagt cgtacgtaaa
    13501 gaaaataact ggacctttgt tctgagcggt ttgttcggtt ccatttttct gcttagtgca
    13561 gatatggttg ctagagtgat tctaccaagt ggggaagtac ctacaggaat tttgattgcc
    13621 ctttttggtg cgccatattt tctgtatgca ctttttatca gacaaaaaca cgcgctgaac
    13681 agttgaaatt tattaaaaaa ggaaggccaa tcatttctag gtcttctttt tattctattt
    13741 atgcatttat ttgaaagttc gattgctatt tttctttttt tcctatacca ttttatgaga
    13801 gaaggaaggg tgagtttttg gaccaattga aagtaagatt acgccggaaa ggaatcgaaa
    13861 agctgaaaaa tctggccaaa agtggcaaga aaaaggaaaa agaacagcga atctataaac
    13921 agctattcgc cagcgagtac tggaagtcag caaaagtgat agggacgact ttatcgaatg
    13981 aatttgaact ggatacacag ccggttatcc aacgagcaga aaaagaacaa aagaaaatag
    14041 ttgtacctaa aactttgccg aaacgtcaga tggcgtttta tgaaatggat gaacagtccg
    14101 ttcttgtacg ttcgagtttt ggtgttcttg agccacaatc agagaagctc tatttgccgg
    14161 agatgatcga tctcctcatt gtaccaggta ttatctacaa tagagccggt tatcgaatcg
    14221 gttttggcgg tggttattac gaccggtatt taaataattt tcataaaaaa acatgtagcc
    14281 ttgtttttcg tgaacaattg aatgaacaat ggcaaccgga gagctttgat cagaagatcc
    14341 aacaattgtt tattgactaa aatgaaatgg gaggttttca tgaattatca acagcaaata
    14401 aaattgcgtg catggttaag acgaccgtta tggacctatg cttttttagg gatacagaca
    14461 gcggtcttcc tcatgatgga attatttccg cgacttgaga tcccttatta tgccggaatg
    14521 tatggtcctt atcttgttca cttcaatgaa tggtggcgtt tagtgacacc aatcttcatc
    14581 cattttggac tgatgcattt cgtaatgaac tcactgatac tgtattttat ggggcagcaa
    14641 atcgaggcaa tctatggcca ttggcgtttt ttcttgattt atatgttcag cgggataatg
    14701 ggaaatacag caagctttgc ttttaacgaa gcgaatgttc tgtctggtgg tgcgagtact
    14761 tcgatattcg gtttgttcgg tgcgttgttt atcttagggt ttcattttaa acataaccca
    14821 gcgatccagc agctagtcag acattttctt ttatttattg tgttgacatt tgtttttggt
    14881 cttctggata cctctgtaga tgtttgggga catgtcggtg ggctaattgg cggattagtg
    14941 ttagggaatg ttttgggtct accgaaacaa cagacaagct attcgataca ccaaaggatt
    15001 ctttctacac tagtttttgt atttcttttt gtaatatgta ttttactggg tttaaaaaaa
    15061 tatggtttac ttgtataata tgaaggaagt gcttaaagat ggagagctta tatgatgtac
    15121 agcagctgtt caaaaaattt ggcatcttta tctatgtggg tgcacgcatc tatgacattg
    15181 aattaatgac tatcgaattg cgtaatctgt atgatagccg tttgattgat catgatacat
    15241 acatgacagc gtggcgcata ttaaaaagag agcaccgaat tgaagaaagc cgaaagaaag
    15301 gaaatttgta atggacaaga agattattgg gattgattta ggtggaacaa cagcaaaatt
    15361 tgcaatttta acaccagaag gagagattca acaaaaatgg agcatcgata ccaatatttt
    15421 ggatgatggt aagcatatcg ttcctgaaat cattgaatca atcaaccatc gtttgaattt
    15481 atataatatg aaagccgaag actttatcgg aatcggcatg ggtaccccag gaagcgtgga
    15541 cagcgaagct ggaacggtta ttggtgcgta taacttaaac tggacagaag ttcaatttgt
    15601 gaaaaaactg atcgaggcag gaacaggaat caaattcgct atcgataatg atgcgaatgt
    15661 tgctgcttta ggtgaacgat ggaaaggtgc tggagaaaac gatccagacg ttgtattcgt
    15721 tactctagga acaggtgttg gcggtggtat cgttgctggc ggaaatttga ttcacggcgt
    15781 gagcggagca ggcggagaga tcggccatat cactgtggat cctgaagggt tcgaatgtac
    15841 ttgcggtaaa cgcggatgtt tagaaactgt gtctagcgct actggtgtgg tacgtctagg
    15901 tcgttacttg gcagaagaat acgcaggaga ttcaaaactg aaagcaatgt tagacaacgg
    15961 tgaagaagta acaagtaaag atatctttga aatggctcaa gaagacgatc cgtttgcatt
    16021 gatggttgtt gatcgcgtat gcttctactt aggtttagct tgcgccaact tggggaatac
    16081 attgaatccg tcaagtattg tgttaggtgg aggagtatcg gcagcaggag aatttttacg
    16141 tagccgtgta gagaaatatt ttaaagaatt tactttcccg caagtaagag aatcaacaaa
    16201 aatcaaatta gcagagcttg gtaatgaagc tggtgtcatt ggtgctgcct cattagcctt
    16261 gaaatttgct taaaaaaacg gaggcattac atggttttat gggtaattaa tatcattttg
    16321 ctattgattg tgcttgcaat catcttttgg gaagtctatc tacgagtaat ggccaagcgt
    16381 tcagcaacga ctttgacaga agaagaattt cgagaaggaa tgagaaaagc acaagtaatc
    16441 gatgttcgcg aaaaagatgt gtttgatgct gggcatattt taggtgcaag aaacatccct
    16501 tacactgttt tgaaagattc attaggatct attcgaaaag accagcctgt ctatatttac
    16561 gatcaaaaga aaagcttgag catccgtaca gcaaataaat tacgtaaagc aggttatcaa
    16621 gagatttatt tacttaaggg tggatatgac ggatggtctg gaaaaatcaa aagtaaaaaa
    16681 gtataaaaca gatgattgta tgacagcttt aaaaaccgaa tcaatcatta gattttgacc
    16741 aagatcacat gaacggcgca atggatagtt gtgccgttca ttttttttat tttgtgctat
    16801 tatctacata tataagctaa gcgaaaaggc agaaagaagg aaacaactat gatcaaatta
    16861 aaacgtgttt accttgatgc tgaaaaagag gatggctata gaatactcgt ggataggttc
    16921 tggccacgag gaatttcaaa agaaaaagcg cagttagatc tgtggttgaa agaaattgca
    16981 cctagtaatg aagcacgcaa aacttttgac catgtaccag aacgatttgc ttcatttgca
    17041 aagaaatacc agcaagaatt gattttcgaa gaagaaaaga agcaagctat ttttaaactc
    17101 agtcaactta tgaaagaaca tccagtcatt acttttgttt atggtgcaaa aaatgaacat
    17161 cagaaccatg ctgttttatt gaaaaaattt atcgaaatgg aggcatgcaa atgaaaatag
    17221 ggatcattgg tgccggacct agaggattaa gtatagcaga aaggattctc cataataatc
    17281 aggacagaca ttctcttgaa ctttttcttt tcgatcccaa tggtcctgga ggtcgagttt
    17341 ggcggttgaa tcagccaccg gagttattaa tgaattctgt ttctcaacaa gtgacgcttt
    17401 ttacagatga aacattgtcc agtggaggat tggtaacaca gggacccaac ttgtttcaat
    17461 ggagtaaagg acctgctaca gattatatcg aacagacggt aaccaaaaat aagcaactaa
    17521 ttatagaaga aatcaatcgt ctggaaaaag atcagcaatc tactcgatgt ttatacggac
    17581 tctatcaacg ctggtttttc tcaaagttgc aagaagaatt tccagcttct attcagtttg
    17641 tttattcttt agtaaaaaaa gtcagcaaaa gaaaagatgg ttatctttta cagacagatc
    17701 agcaaagcta ttctatcgat cagcttgttt tagcaagcgg tcactgggaa aatgatgaga
    17761 cagaagaaga aagagtgtgg gtagactacg caaagaaaaa tgatttactg tatcagcttc
    17821 cttctaatcc tgcagatgtc gatctttcga agataccgcc taaagaaaat gtctttttaa
    17881 gaggtctagg cttaagtttt tttgattatg tcggattgtt tacagtatca agagaagggc
    17941 gcttcgagaa cgaaaaagga aaacttgtct atcatccatc aggcaaggaa ccgattgtat
    18001 acagtggatc aagaaggggg ctcccttatt accctcgagg aagaaaccaa aagcaaggcg
    18061 gatcaatggc atggccacgg ttactaacaa aagaaaacct ggagcaatgg catcagtcgg
    18121 gatttttgac tggcgaaaca ttttttgact atctgaaaaa agacgttgag ttgttttatt
    18181 acaagaaaat catcgaagaa tatcatttgc cgattccaaa gaaaaatttt gagcatgatt
    18241 ttctctccct ctcttcagag gagtgtctcg gaaagcatcc agcactaatc ccttatagat
    18301 gggattggtc gtatttagaa attcctctta cctatcagga tgagtccttt gcagaagcta
    18361 gccgagcatt tattgaaggg cagataaaag aagcggaaaa aggcaattgc acaggagcat
    18421 ttgcttcaac atttgatgca ttaaaagact ggcgtgatcc aatccggcag gctattgaat
    18481 ggcacgtttt ttctgcaaag gaatacaaag aaatactatg gggatggttt actcatctaa
    18541 atagcttttt aacgatcggt ccgccagtca ttcggacgaa agaattagca gcactgatag
    18601 atgcgggtat ttttcatttg ttcgaaccgc catttgatat tcagcaaaag cacaaccgct
    18661 atgttatttc tctacaagat aaagaaatca gcagtcgcta tttgattgaa gctcgattgc
    18721 cacaaacaag cttttctcgt tcaagtaatc ctgtcataaa aaatttgaag gaaaacaaac
    18781 ttgttcgccc tttttcattt tcagataata caggaagtta tcattcagaa gctatagatg
    18841 ttgagcgagg tacgaatcgc gtgattgatg cttcagggga aatccagtct gacttttatt
    18901 gctatggaat acctgttgaa ggtgtggatt ggctaactgc agcagtagct agaccttata
    18961 cagatccatg gaatctgaga caggcagata aaatagcaca acttatattg actgacaaat
    19021 aaaaatacgc atgatgactt atctgttctt tcacaagtct tcatgcgtgt ttttaaataa
    19081 ttattaacga gaaacgcgtt tgcgcattgc ttttttacgg ttttcttcga tcattgcttc
    19141 tttttcgtca attggatcga tcactgtttt tttcacagaa gcgaccaaac cagcaacggc
    19201 agcggctgtt gccagacttc ctactaatat tccagataca aattttttca ttgaatccac
    19261 ctcatttatt atttgttata tctattatgg aacaaaagag aaaaaaaggc tagttttacg
    19321 tttgtttgta aacctttgca aaaaatcctt gaaaatgttt actaaatgtt ttattataaa
    19381 tttaccatat gaatttacga aattttactt tgtttgtttt caccataaaa gtaaacttcg
    19441 tttttttaaa ttatatataa tcaacaaaca caattttact aatcaaagga gtgtttttta
    19501 tgacaatttt agtactaggc ggagccggtt atatcggttc gcacgctgta gaccagctag
    19561 ttcaaaaggg gtatcaagta gctgtggtag ataatttgct cacaggtcac aaacaagcag
    19621 tacatccaga tgctcatttt tatgaaggag acatccggga taaagaattt ctacgttccg
    19681 tatttgaaaa ggaaccgatt gaaggagtaa tccattttgc tgcaagctct ttagtaggag
    19741 aatctgtcga aaaaccattg atgtatttca acaacaacgt atacggtatg caaatcttac
    19801 ttgaagtcat gcacgagttc aatgtgaata aaatcgtgtt ctcttctact gcagcaactt
    19861 acggagaacc aaaagagtct ccaatcacag aagatacacc agctaatcct aaaaatccgt
    19921 atggtgaaag taaattgatg atggaaaaaa tgatgaagtg gtgtgaccaa gcatatggca
    19981 tgcgctatgt cgctttgcgc tacttcaatg tagccggagc aaaagcagat gcatctatcg
    20041 gagaagatca tacaccagaa acgcatcttg tcccaatcat tttacaagta gctcttggtc
    20101 aaagaaaagc attggctgtt tatggagacg attatgatac accagatgga acatgtatca
    20161 gagattatgt tcaagtagaa gatttgattg ctgcacatat tttagctttg gaatacttga
    20221 aagaaggaaa tgaaagcaac ttcttcaatt taggcagcag caaaggatac tcagtcaagg
    20281 aaatgctaga agcagctaga gaagtgacag gaaaagaaat tccagcagaa atagcaccaa
    20341 gaagagctgg agatcctagc cgattagtcg cttcaagtga aaaagcgaga gaggttctgg
    20401 gttggaaacc tgaatacaca gatatcaaag caattatcaa aacagcatgg gattggcatg
    20461 tcagccatcc aaatggttat gaagaatagg ggaatgagat atgtcaatca gtcaaacgat
    20521 ttgtgatttt gccacacttg cgatcgaagc tggcggatgg atggaaatgg accgcttata
    20581 tttacagaat cgtcttttag ggatggtagg agaagatgct ctagaaagca ttgaagtaag
    20641 accagttaag gaagaatctg tagacttatt ggatcagctt gtcgctaagg caagagaaaa
    20701 tggtgttctt tcagaattgc cagcagaaca agagattttt gaagcgcaat taatggattt
    20761 tctcacaccg ccaccttcag tcgtcaatgc attctttgca cagcactatt cgaaaagccc
    20821 agaggaagca actgagtatt tctttaattt aagtaagaaa aatgactaca tcaaaacaag
    20881 agccatcgca aaaaacatca aatttccggc agagtcggag tatggtgaac tggaaatcac
    20941 aatcaattta tctaagccag aaaaagatcc aaaacaaatc gcagcagaac gcgaggcggt
    21001 aaaagtagac tatcctacct gcatgctttg catggaaaac gaaggatata gaggtcgctt
    21061 gaactatcca gcccgcacca atcaccggat tattcgaatg aatctagacg gtgaaagctg
    21121 gggattccaa tattctcctt atgcttatta caatgaacat tcgatcattt tatcagaaca
    21181 acaccgcccg atgaaaatca caaaggaaac atttgctaga ctgcttcgga ttactgaagt
    21241 cttgcctcat tactttgttg gttcgaatgc tgacttgccg attgttggag gatcgattct
    21301 ttctcatgat cattatcagg caggacgtca tgaatttcct atggcaaaag caccgataga
    21361 aaaacttatc aaactagcag attatccgca agtcatcgca ggagtcgtga aatggccgat
    21421 gtctgtgatc cgtttgcaat caacagagaa aaaattgttg attgaagcag ctaactcagt
    21481 attggaaaag tggaaagcat attcggatga aacagtatct atcagagctt tttcagcaga
    21541 tggtacacca caccatacga ttacgccaat tgcacgaaga agggacaatt actttgagtt
    21601 ggaccttgtc cttcgagaca acaatgtttc agaagaacat cctgatggga tttttcatcc
    21661 acataaagat gtccaacata tcaaaaagga gaacattggg ttgatcgaag taatggggct
    21721 tgctgtttta ccacctcgtt tgaaaccaga actagtagaa gtagagcatt tcttattagg
    21781 agaagaaaac cagatggctg aatatcatcg tccgtgggca gaacaattaa aaaaagaaca
    21841 tcctgatttg acgaaagata cggtcaccga tgtcgtacaa aaatctgtag gtcaggtttt
    21901 tgcacgtgta ctggaagacg ctggagtatt caagcgagat gaaaaaggac aggcagcgtt
    21961 tgaacgattt actgcaattt tataaacgta aaaaaggagg agagacaaat ggcaacaatt
    22021 aaagacattg cgcagttggc aggagtttct cctgctactg tttcaagagt tctcaactat
    22081 gatcctgatc tttccgttgg cttagccaca aagcaaaaaa tttttgaagc agcagaacgc
    22141 ttaaattata cgaaacatcg taaaaatgca gcaaatacta agcaaacgct tcgcctgatc
    22201 cagtggtacg acgatacgga agagcttgaa gatctttatt atttatctat tcgtctagga
    22261 atcgaaaaaa aggcagaaga agcaaacgtt actttattga aagaaacgtg ggattccatt
    22321 agtgatcttc cgacagatgg aacgatcgca ctaggaaaat tcgacgaagc tcagttatta
    22381 gaaatgaaag gatcccaaaa tgccttgctt ttggtagatt ctgacggcac ttctcaagga
    22441 atcgactctc tagttgtcga ctttaagtca agtgttcaaa aagtcattga acattttgtc
    22501 tcccataaag cgcaacatat cgctatgctt gctggaacag aatatacgaa gaaaaaccat
    22561 cagcggctaa aagatcccag aattatggca tttcaacaag ttttggcaga aaaaggctac
    22621 gacgaaggtc caattatcga agcagatttt tctgtcgagt caggatatca agcagtgaag
    22681 cagtatttaa aaacgaatcc gcatgttcct gatgcgcttt ttgcagctaa tgatgcatta
    22741 gcgattggcg cactgaaagc gattcaagaa aaaggtttag tggtaccaga agatatttct
    22801 gtgatgggtt tcaatgatgt cagtgtagcg aaatatgtaa cgccctctct ttctactgta
    22861 aaagtttata ccgaatggat gggagagcta gcagtggaga cgattcttca attaagtaat
    22921 tccaaagcac cggtttcaag aaagattatt gtggaaacag agttgattat tcgagaatca
    22981 acgaaataaa agatggaaaa gctgtgggga aatgaagtga taccgcagct tttttgtgtt
    23041 tcaggaaggg gcaaaatttg cccgccagca gataatcatg tatcattgta ctagttttgc
    23101 ctttggtatt ttcatcctca gaataaaaaa gtatgctaca atggaaggcg agaatgtcat
    23161 agcagaaagg atcaaatata tgattacatt aggaatagat actgcaaacc aaactttggc
    23221 gatcggtgtg gtagaagacg aacaaattct tggacaaata caaacaaata tcaaacgcaa
    23281 ccacagtgta acactgatgc ctgcaatcga ccaattgttt gcagatcttc aaataagtcc
    23341 aaaagacatt gaccgaatcg cggtttctga tggtcccggt tcttatacag ggcttcgtat
    23401 aggtgtaacg acagcaaaaa cgattgctta tacattagat aaagagctag taggagtatc
    23461 tagtctgaaa accatcgcgg ctaattgcat cggtgtggat aaaattattg tgcccatgtt
    23521 tgatgctcga agaaaaaatg tatacgctgg ggcataccgc tggaaagaaa atagattaga
    23581 aattgtactt gaagatgtac atatttctgc ttctgatttg ttcacacaac tacaaaagct
    23641 gaatgaagct atttatttcg tcgggagtga ttgtcacaaa ttcttctatg aaataaagga
    23701 aatattgcct agtgcgatga ttaatacagt tccagcatgg gatattccaa gtggtgtaac
    23761 tgtggctcaa ttaggtgctt tagctgaacc agttgcagag aaacaagctt ttcttcctcg
    23821 ctatttaaaa cgggtagaag cagaagaaaa atggttggag acgcacacac ctggagacga
    23881 aagttatgtt gaaaaaattt agagcgtatg ccagaagctt ttttcaagat aaaatgattt
    23941 atacagaaaa aacaatcgaa caaatcgatc gtcgttacgt actaagagaa ttgactacag
    24001 aagatatcaa agagctgctg gatgtcgaac gagaagtcta taatggcgaa ttgccatgga
    24061 caaaaagtgc ctttatatca gaattgaagt caccgcttcc tcatctatat ctaggtatct
    24121 ttgataatgg aagaatgatt ggttttatcg gttcaagagc gttcggttta gattgccata
    24181 tcacgaatat tgccgttcga ccggcatatc agcgtaaacg aatcggttcg ctgcttattg
    24241 acgaaatcga gaactttgct ataatgaatc gctgtgagac gatgtcatta gaagtgcgta
    24301 tgagtaatca agatgcacaa agactttatc ggaagttagg ttttcaagca acaacgatca
    24361 aaaaaagata ttacactgaa acaaaagaag atgcgttgga tatgataaaa cttttagaaa
    24421 atgagtgaga ttagttgatt tgcagaaaaa aagattttga tgaagcgtac ttggcagaat
    24481 gcgtatggat gattagcgaa aatgcttatc cacatggttc accttggacg aaaatgcagt
    24541 ttttggcaga catccaacag cctcactctg attatctgct tttagttgaa gataaccaga
    24601 tctgtggctt tattggatac tcgaaagtaa tagatgaagt cgagatcaca aatattgctg
    24661 ttgcagtttc agaacaagga aaagggcatg cacggcattt gttacaatta ctgattacgg
    24721 aacaaataaa agattcgctg catgtttttt tagaagtacg tctatctaat gaagcagcaa
    24781 gaaaacttta tgaatcagaa aagtttcgta tattaggtaa acggaaatca tattatcgca
    24841 atccgacgga agatgcgatc attatgagca gaaagttaaa aacggagacg atgaaatgaa
    24901 tgaagaattg attctggcga ttgaatcaag ttgtgatgaa acgagtgtag cggtcgttag
    24961 aaatggaaca gagatcttat ctaacatcgt tgcttctcaa ataaacagtc ataaacgttt
    25021 tggtggcgta gttcctgaag tagctagccg ccatcacgta gaacaaatca ccttatgctt
    25081 ggaagatgca ctggtagaag ctggtgtgtc ggcagaagat ttatcggcag tcgctgtcac
    25141 ttatggacca ggacttgtcg gctcgttgct gattggtatt tctgcagcta aggcttttgc
    25201 ttgggcacac caattgccgc ttattcctgt aaaccatatg gcagggcata tctatgcagc
    25261 ccgtctggtt aaaccattcc agtttccatt gatggcactt cttgttagcg gaggacatac
    25321 agaattagtc tatatgcaag aagatggatc atatgaaatc attggggaga caagagatga
    25381 cgcagcagga gaagcttatg acaaagttgg aagagtatta ggtctttctt acccaagcgg
    25441 aaaagaaatc gatcagctag ctcatcaggg aaaagataat taccattttc cacgagcgat
    25501 gatccatgaa gataattatg atttcagttt tagcggatta aaaagtgcat ttatcaattt
    25561 ggtgcataat gcacaacagc gtggagaaga tctagacaaa aatgatttag cagctagctt
    25621 tcaagcaagt gtgatcgatg tattgattac taaaacactt cgagcttgtc aaaattatcc
    25681 agtcaagcaa ctgattgtag ctggaggtgt agcggccaat caagggttgc gtgaaggatt
    25741 gcaggatgct ttggcaacta aactccctga ggtagaacta gtgattcccc ctcttcgact
    25801 ttgtggagat aatgctgcaa tgattggagc agcagcacat gtggaaatgc aaaaaagaaa
    25861 ttttgctagc tatcagttga atgctgatcc aagcttggtt ttatctgaat aaagaggttg
    25921 tgaaaaatct gccctgcatc aagtaataag aacagcccag gaaaaacggc ttctcatgtt
    25981 tttgacctgg ctgttcttat taccgcgtat gcaagctttt gaacgccgtt taatcaagag
    26041 ttcgtaagcc tgtcgtttaa ctctgattca caaggaacaa tttcaaaaaa cagctcctca
    26101 tgtttatgaa cattatgact tgtgaccgaa gagttgacag gtacacaccg tttaatcgaa
    26161 ataagggctg tgacacgctt ttgtcaaagc cctatttttt acagcttatt catcattatc
    26221 cgttcctctg attgccctca ctgattaatc gtttattgtc gaggaatatc gaataatcta
    26281 ggtcggatga ggacaagacg cttcctctag ttaatctatc agtatttttt gcaaacagtg
    26341 aatattacat aactgaaaca cacatagaaa atctttgagt cttgcccagt gatctaaaac
    26401 tgccggatct ttcagaagtt ttagggagga aaataagcag tgaccctgat aaa
//
LOCUS       DAZKNV010000036        25501 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000036 DAZKNV010000000
VERSION     DAZKNV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.036"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..3660
                     /locus_tag="ACG8M1_001718"
     CDS             133..3660
                     /locus_tag="ACG8M1_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFQ0422432.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="ACG8M1_001719"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="ACG8M1_001719"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFQ0422433.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="ACG8M1_001720"
     CDS             7448..7789
                     /locus_tag="ACG8M1_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFQ0422434.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="ACG8M1_001721"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="ACG8M1_001721"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFQ0422435.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /gene="pheT"
                     /locus_tag="ACG8M1_001722"
     CDS             9146..11566
                     /gene="pheT"
                     /locus_tag="ACG8M1_001722"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFQ0422436.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG8M1_001723"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG8M1_001723"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFQ0422437.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="ACG8M1_001724"
     CDS             13000..13737
                     /locus_tag="ACG8M1_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422438.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="ACG8M1_001725"
     CDS             13751..14566
                     /locus_tag="ACG8M1_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0422439.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="ACG8M1_001726"
     CDS             14579..15226
                     /locus_tag="ACG8M1_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0422440.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="ACG8M1_001727"
     CDS             15242..15898
                     /locus_tag="ACG8M1_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0422441.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="ACG8M1_001728"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="ACG8M1_001728"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFQ0422442.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="ACG8M1_001729"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="ACG8M1_001729"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFQ0422443.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="ACG8M1_001730"
     CDS             18240..18758
                     /locus_tag="ACG8M1_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0422444.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /gene="cbpB"
                     /locus_tag="ACG8M1_001731"
     CDS             18865..19365
                     /gene="cbpB"
                     /locus_tag="ACG8M1_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFQ0422445.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="ACG8M1_001732"
     CDS             complement(19645..20565)
                     /locus_tag="ACG8M1_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFQ0422446.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20691..21743
                     /locus_tag="ACG8M1_001733"
     CDS             20691..21743
                     /locus_tag="ACG8M1_001733"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFQ0422447.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="ACG8M1_001734"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="ACG8M1_001734"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFQ0422448.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="ACG8M1_001735"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="ACG8M1_001735"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFQ0422449.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="ACG8M1_001736"
     CDS             complement(23383..24144)
                     /locus_tag="ACG8M1_001736"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0422450.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="ACG8M1_001737"
     CDS             24333..25427
                     /locus_tag="ACG8M1_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFQ0422451.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4424 c         5383 g         7247 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg tgcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 g
//
LOCUS       DAZKNV010000037        25478 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000037 DAZKNV010000000
VERSION     DAZKNV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.037"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(175..540)
                     /locus_tag="ACG8M1_001738"
     CDS             complement(175..540)
                     /locus_tag="ACG8M1_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422452.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            748..1230
                     /locus_tag="ACG8M1_001739"
     CDS             748..1230
                     /locus_tag="ACG8M1_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422453.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1427..2317
                     /locus_tag="ACG8M1_001740"
     CDS             1427..2317
                     /locus_tag="ACG8M1_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFQ0422454.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            2643..5117
                     /locus_tag="ACG8M1_001741"
     CDS             2643..5117
                     /locus_tag="ACG8M1_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0422455.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5220..6956)
                     /locus_tag="ACG8M1_001742"
     CDS             complement(5220..6956)
                     /locus_tag="ACG8M1_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0422456.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6953..7657)
                     /locus_tag="ACG8M1_001743"
     CDS             complement(6953..7657)
                     /locus_tag="ACG8M1_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0422457.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7788..8293
                     /locus_tag="ACG8M1_001744"
                     /pseudo
     CDS             7788..8293
                     /locus_tag="ACG8M1_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
     gene            8253..8591
                     /locus_tag="ACG8M1_001745"
     CDS             8253..8591
                     /locus_tag="ACG8M1_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFQ0422458.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            8612..10030
                     /gene="ffh"
                     /locus_tag="ACG8M1_001746"
     CDS             8612..10030
                     /gene="ffh"
                     /locus_tag="ACG8M1_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFQ0422459.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDTVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10142..10720
                     /locus_tag="ACG8M1_001747"
     CDS             10142..10720
                     /locus_tag="ACG8M1_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFQ0422460.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10724..11245
                     /locus_tag="ACG8M1_001748"
     CDS             10724..11245
                     /locus_tag="ACG8M1_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFQ0422461.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11324..11878)
                     /locus_tag="ACG8M1_001749"
     CDS             complement(11324..11878)
                     /locus_tag="ACG8M1_001749"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFQ0422462.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12131..12406
                     /gene="rpsP"
                     /locus_tag="ACG8M1_001750"
     CDS             12131..12406
                     /gene="rpsP"
                     /locus_tag="ACG8M1_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFQ0422463.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12418..12669
                     /locus_tag="ACG8M1_001751"
     CDS             12418..12669
                     /locus_tag="ACG8M1_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFQ0422464.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12793..13584
                     /locus_tag="ACG8M1_001752"
     CDS             12793..13584
                     /locus_tag="ACG8M1_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422465.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13754..14275
                     /gene="rimM"
                     /locus_tag="ACG8M1_001753"
     CDS             13754..14275
                     /gene="rimM"
                     /locus_tag="ACG8M1_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFQ0422466.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14265..15026
                     /gene="trmD"
                     /locus_tag="ACG8M1_001754"
     CDS             14265..15026
                     /gene="trmD"
                     /locus_tag="ACG8M1_001754"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFQ0422467.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15162..15509
                     /gene="rplS"
                     /locus_tag="ACG8M1_001755"
     CDS             15162..15509
                     /gene="rplS"
                     /locus_tag="ACG8M1_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFQ0422468.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15819..16061
                     /locus_tag="ACG8M1_001756"
     CDS             15819..16061
                     /locus_tag="ACG8M1_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFQ0422469.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(16149..16295)
                     /locus_tag="ACG8M1_001757"
                     /pseudo
     CDS             complement(16149..16295)
                     /locus_tag="ACG8M1_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            16352..16666
                     /locus_tag="ACG8M1_001758"
                     /pseudo
     CDS             16352..16666
                     /locus_tag="ACG8M1_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
     gene            16695..17954
                     /locus_tag="ACG8M1_001759"
     CDS             16695..17954
                     /locus_tag="ACG8M1_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422470.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            18007..18903
                     /locus_tag="ACG8M1_001760"
     CDS             18007..18903
                     /locus_tag="ACG8M1_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422471.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            18914..19783
                     /locus_tag="ACG8M1_001761"
     CDS             18914..19783
                     /locus_tag="ACG8M1_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422472.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            19793..20468
                     /locus_tag="ACG8M1_001762"
                     /pseudo
     CDS             19793..20468
                     /locus_tag="ACG8M1_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            20674..22338
                     /gene="alsS"
                     /locus_tag="ACG8M1_001763"
     CDS             20674..22338
                     /gene="alsS"
                     /locus_tag="ACG8M1_001763"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFQ0422473.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            22351..23061
                     /gene="budA"
                     /locus_tag="ACG8M1_001764"
     CDS             22351..23061
                     /gene="budA"
                     /locus_tag="ACG8M1_001764"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFQ0422474.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            23191..23688
                     /locus_tag="ACG8M1_001765"
     CDS             23191..23688
                     /locus_tag="ACG8M1_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFQ0422475.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            23873..24133
                     /locus_tag="ACG8M1_001766"
     CDS             23873..24133
                     /locus_tag="ACG8M1_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422476.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(24495..24734)
                     /locus_tag="ACG8M1_001767"
     CDS             complement(24495..24734)
                     /locus_tag="ACG8M1_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422477.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            25020..25334
                     /locus_tag="ACG8M1_001768"
     CDS             25020..25334
                     /locus_tag="ACG8M1_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422478.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT         8456 a         4308 c         5238 g         7476 t
ORIGIN      
        1 atatctatta ttggaatcat tattgctgca attattacac aactgttttt agtgtttgga
       61 gagaagaaaa gaagtaaaaa atagaaaaac tagtgatagt tttggtgata taagaaaaac
      121 atatatgtat aaaaagaaga aagtagcttc tctttgtaca tatatggttt gtttttatgg
      181 atgccgagct tttttataag ataaggctac cgcccataac gacccaagga tttgtggaac
      241 taagtaaata cctgcaagaa gcaagatcag ctgggtcggt tttaaaggat gatagaagta
      301 acgccattca gtaaaattgg cgcaaaataa ataggaagtg acagtagata taatattggc
      361 aatgaataaa gatataatac gcctgttcct ttgaaaataa tatccagcaa aaagagataa
      421 aaatatcaat gtgatgaacc cgcttacgga atgataacga aaatcaagca gtaaggcgaa
      481 atgcacataa ggaacaaaag ataaaagcaa cggaaggttt ttccagcaag tttttatcat
      541 ctttcatcac cacctaacaa gtgttattat tttgttagtt ttattgtaaa ttgaatcctg
      601 caataatcaa ttactttttc attatttcta gattaaatga ataaactctc atgccattat
      661 ctctaaaaaa aaagtttttc cccctaattt ttttagatag aaaattgtat agtatgatga
      721 gagaaaaagt agtttggggg aacgttaatg agaagaaaag cagtaatcga tcggctttat
      781 ttattttttt ggttttttcc tatcgttttg ctacctttta catgggtaaa tgctgttgta
      841 caaggtgcgg agatattagg cctgatccaa ggaagcggat tagtggtttc taggaatttt
      901 ccagctttga ctgttttcta tttagtgata agtgtaggtc tcttattacc aaaatctctg
      961 atcaatcact acaattggca gctgctttac ttttcttgct tattagtatt tacatctatg
     1021 ttttctttgc tgcctcgctt gattatcggc cctaatggtt tgagcgagag tggattgaag
     1081 gattcagctt attcctccat gtatttcttg acgatcaaac catggttcta tttagtaatt
     1141 gcctcattta ttcttgcaac atttttttac ttctggacag aaatcaggat aaaaagtgaa
     1201 cgatctgtat ctataaaaaa taactattga tggtggatca tcagtaaaaa agcatatgag
     1261 ctgcgtaaaa tgcatgtttc tcatatgctt tttttattat tatgtaaaga atgcgaaaaa
     1321 cgtttacatg atttttacat aacttaacta tatttttaca gcaaccatac gagggattta
     1381 cagtcgactg ataaacttta gttgtaaata agaaaggagc aataaaatga aaaaagtatt
     1441 gtttactcta ggtatgatgg gaattctttt agccggatgc ggctcaggat caggaaatac
     1501 agatggctct gccacacaaa ataattcaag tgactcaaat gaacaagtaa aaatcgttgc
     1561 ggtaggttcg acagcattac agccgttagt cgatgcagca caagaaagct ttgtacaaga
     1621 aaatccaaat tatcaaatct ctgtacaagg aggaggaagc ggaactggtt tgagccaagt
     1681 cgaagctgga gcagttacta tcggaaactc tgatgtattt gcagaagaaa gagacggagt
     1741 tgatgcttca aaattagtgg atcataaagt agcagtggtc gggatggcac caatcgtcaa
     1801 taaagataca gatgtcaaag atatcaccaa acaggaattg attgatatct ttacaggaaa
     1861 aatcactaac tggaaggaag ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc
     1921 aaacggcagc ggtacccgcg cgacattcga aaaatgggga ctggatggtg ctacccctgt
     1981 gcagtcccaa gaacaagatt catcaggaac agttcggcag ctggtaagtc aaacaccagg
     2041 agcaatcagc tatttagctt tctcatatct cgatgattcc acacaagcac taagtatcga
     2101 cggtgtagaa ccaaaagaag agaatgtagc agataacagc tggggaatct ggtcatatga
     2161 acatatgtac acgaacggaa aaccttcccc tgaagtccaa aaattcttag actacatgat
     2221 gacagaagaa atccaagaag gacctgtcaa agaattgggc tatttaccaa tcacaatgat
     2281 ggaagtagaa cgtgatcacg aaggaaatat caaataacta gcagataaac atgccacggt
     2341 agtcgttact attaaggaaa aatcaactat gtttccccac atatacattt ttcctttaat
     2401 tgtgaaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat
     2461 tgaacaccgt ttattcgaaa aaaagagcta cgacatagaa ctgtcgtagc tttttttttg
     2521 ctatatgaca ggaatgaaag gtgtttgcaa gcttaatgtg aggaacactt tccatatctg
     2581 ttctatactg gataggagaa gtttggaaat atccagaaaa cgaaatcaat cgaggtagcc
     2641 acatgaagaa taaatggata aatcgaagta aaaaaaagaa agtaacacaa agatcatcag
     2701 ataaagtcat ccgtcttttt ccatcgtata aagaaggatt aacggcagat caagtcaagg
     2761 aacgaataga aaaaggtgca gcaaataatt cagtcgatcc cacattcaaa acaaatcagc
     2821 aaatcgtatt ggaaaacata tttacgtatt tcaatttgat ctttcttatc ttagccattt
     2881 tgctttgttt agtagaatcc tataagaact tgactttttt accagttatc atagccaata
     2941 caggaatcgc catttttcag gaaattcgat ccaaaaagat cttggacgaa ctaaatgttt
     3001 taaatacagc aaaagtcaat gtcatacgag acgggataga acaaacaata gatatagaag
     3061 accttgtaat agatgacatt gttattttag agactggaca tcaaattcca gcagatgcag
     3121 aggtcgtgga agggaaactg caagttaatg aggctttatt gacaggcgaa gcagatgaaa
     3181 taaccaaaga aataggcgat ccattaatgt ccggcagttt cattgtttcc ggaaaagctt
     3241 acgcccgatt agacaaagtt ggagcagatt cgtatatttc ccagctgaca gtcaaagcca
     3301 agacaatggg agaaggagaa cagtcggaga tgattgcttc tcttaatcaa ttgatcaaat
     3361 ggattgggat catcattatt cctatcggta tcctgctttt ttctcaaagt tactttttta
     3421 atggaaacac gatcaaagaa agtgtcgttg caatggaagc agcattgatc ggtatgatac
     3481 ctgaaggact gtacttgctg acgacgattg cattagcatt aagtgcgact aaactagcaa
     3541 agcaaagagt tcttttacac aatatgaaaa gcattgagac attggcaagg gtaaatgtcc
     3601 tttgtgtaga taaaacagga acgatcacag aaaataaaat gtctgttcaa aaagtgatcg
     3661 tctctaaaaa acaagaaata atcagtcagt cagatcaatt ggaagcatgc attgctgact
     3721 atgcaaaagc gatggcagga gacaatgcaa caatggaagc tgttaaagca tattttacaa
     3781 aaaccactga tcaatcctat caccatgtta ttcctttttc ttctgtccaa aaattcagca
     3841 gtgtagcgtt ggcagacaag gtgtatgttt taggagcgcc cgaaatggtt ttgcgcgatc
     3901 aattgccgga atatgcggaa gagtttgttt ctttcgctga aaaaggctat cgcgtgttgg
     3961 tctttggtgt gtacgatggg attcttgaag aaccagtatt gacagaagca gtcacaccat
     4021 taggctatat tctgattgct aatcctatca gaaaagaagc aagagccaca tttgattact
     4081 tcaaaaaaca gcaagtagcc atcaaagtga tttctggaga taatccgctc accgtatcca
     4141 atgtagctgt ccaagcaggg atttcacatg ctgatcagta cgttgatgca tctaaattat
     4201 cagaagaaga atatgaagca gctgtcgaaa aatatacagt ttttggacgc gtcaagccag
     4261 aacaaaagaa aatcttcgtt caattgctaa agcgtcgtaa caatacagta gctatgacag
     4321 gtgatggcgt gaatgatatt ctagccatga aagaagcaga ctgcagtata gcgatggctt
     4381 ccggaaatga agccgccatg caggcctcac aagtggtctt acttgattct gacttttcac
     4441 gcatgccaga agttgttgca gaaggacggc gcgttgtgaa caatattgag cgatcagcca
     4501 gcttgttttt agtgaagaat attttctcct ttttgctctc actgttttca gtgatctttg
     4561 ctctgaccta tcctttagaa ccatcacaaa tcacattgat tagtttgttt actatcggac
     4621 ttccatcttt cttgcttgct ctagaagaaa acaaaaagcg aatcagaggg aaattcatca
     4681 tgaatgtgat ggaaaaagct gtgccaggtg gactaacaga tatgatcgta gtcggtgcgt
     4741 tggtgatctg cggggtgact ttgaatctaa ataaaacaga tgtttctaca gcatctacca
     4801 tgcttttgat tgcagtaggg ttcctcgttc tctataaaat ctgttcaccg ctgaataaat
     4861 tcagaagtca gatcattctt ttctgtgcta gcggtaactt tttttcggtc atctttttgc
     4921 ataagctgtt ttcaatcacc ggtatctcag ctgtatcact tttgctgttg agcattctat
     4981 ttttctcggc agattcgatt tttaggcatt tgaccacatt ggtagaatat ttgtttgaac
     5041 gtaaaaatga aaaagagcaa aagccgttta gtcgcgtagt taaaaaattt ctatcgatat
     5101 ttaaacgaga aaattgacga aaagtatctc aaaaaagagt aaaaaagaac aaccactcgt
     5161 gtatctttcg aagcaggatg agtcatccaa ctttaaaacg cacgagcagt tgctcttttt
     5221 tacattttcg gaatggtaac ggtgaaagtc gaacctgttc caagatgact gtctacagta
     5281 atcgtaccat gaaggagttg cacgtagtct tttacaatcg ctaaccctaa tccggtcccg
     5341 cctgaatgcc ggcttcgcgc cttgtctacg cggtaaaaac gctcaaagat ccgttcctga
     5401 tcctcaatgt cgatacctat accaaagtct tggacagaaa acgatagatc atctgttgcc
     5461 tgatagcgga taataatctc gctgtcgctt tttgaatatt ggacagcatt ttcaatcaga
     5521 tttttgataa ttggataaag gatatctgtt ttagtagtaa atggttcgtt ctttccaatc
     5581 aatcgaatcg tcaaccgttt cttttcgatg attggctgat aattttgaac gatttgctgg
     5641 aaataaggtt ctgtataaat tgtctggatc tcgtaagaat tctcgccatc ttttgacagc
     5701 tggatgattt cccgaatcag tttatctaac cggatcgcat ctttttgcat gatctcaaga
     5761 aaagaagtca gagtttgcgg gtcatctttt gcaccatcca gtaaagtctc ggtaaaacca
     5821 atcagtgaag tcacaggagt ttttaattcg tgagagacgt tgccaacgaa atccttttgt
     5881 agcttttcta aacgtcgcac tttcgttaag tcatacgcca cccctagaat ctgtccggta
     5941 ccttctgaat tagtaaagta gcgcaaactc aagtctaatg tctgccgacc ttctgtaagg
     6001 gtgatctcct gatggatcag cggatgctca ggagtcactt gatgaatcag ctgaatgagt
     6061 tttggctctt gaatgacttc tgtgtaccgc tgttcaggtt gatagcttac cacgtttaaa
     6121 tgtagctgca tctttggatt aagcagtagt aaacgagaat cagcatcatc aatcaggaat
     6181 acgccaatca tcagttcgtt cagtaacgta tataattgct cttctgtggt agtatacgcc
     6241 cgatacatct tactcatttg ttcgctcaac gcattgatcg tctgatacaa ttcttcccat
     6301 tgatcgggtg tttgcatgat tacttccgcc tgattaggat tttgcaccat tttttttagt
     6361 acgggcagca cggttttcaa tggctggttt ttttgataga tcagataata gatcattcct
     6421 gcaagaacaa ggaagaaaga cagaaagaag aaaaagaccc aacggcgaaa actctcagtt
     6481 ctcggtaaaa aaccgcttgt cggttctgcg atacgtaaaa tggcttctaa ctggccactt
     6541 tttttgactg gtaatgcgac atataaaaga tccccattca aagtagtact tttgcgcaaa
     6601 gcgctaccta ggttcccacc attcaatacg gctttgattt cgggacggga gtttcgctgt
     6661 tcattcaatg tttcattgtt tgtgtcaaat aagatctttc cagtagcatc cattaaagta
     6721 atccgttcgt tcgactgatg gacgaattct tccaaagcag ttttgttttg cgctgcttgg
     6781 aggttttcga catctaattg ccggatcagc agttgtgctt tttttgtcag gtagctttct
     6841 tgctgttcca cgatctgctg ttgaaaataa tgggaaatca attgccagcc accaaaaaac
     6901 aaactaacta aaagaataag aaagaagaga cgttcataaa tttttttcca tttcatcgtt
     6961 tgggttcctg aaacttatag ccaaatcctc taatagtcac caagtacttt gggtgttttg
     7021 gatctcgctc gattttttct cgcaaatgac taacgtgtac atctacgatt cggctttgtc
     7081 ctgcgaagtc aaaattccaa atgcggtcta gcaatgtgtc tcggtcgatc acacggtctt
     7141 ttcgtttcat gaaataaaca agtaattcaa attctttcgg tgttagttca atcagatggt
     7201 cgtctacggt cacttgataa ttggtcaaat cagcagtgat ttgtccaatc gatagatatt
     7261 caggctcagc ttcatctttt gattgcttac gaggttcaat tcgtctgaat attgctttca
     7321 tacgggctaa tacttcgcga ggactaaatg gtttggtcaa atagtcgtca gcacctattt
     7381 ctaggccaat gatccgatcc acttggtcat ctttagccgt cagcatcaaa atcggtgttt
     7441 catttttttc ttgacgcagc cgctgagtga tctccatgcc atccatcgtt ggaagcatca
     7501 catctaaaat gatgaaatca aatgattgtt ctaatgctaa ttctaatcct tcgcctccat
     7561 ctgtggcact ggttaccttg tagccttctt tttccaaatt gaacgtcaag agcgttacaa
     7621 tagaaggttc atcatcaaca actagtattt ttttcattca aatctccttt aaataggttt
     7681 cattctgttt atattttagc atagaatcag tacaaagggc tattttacaa aagaaataaa
     7741 tggtataata ggaaggcact ttgctgaata gaaaggaaga gcagtcaatg attggaatca
     7801 gtgcatgttt aggcggtctg gcctgtcgct atgatggaca gaaaaaagaa gtaccagaat
     7861 tgatggaact agttgaaact ggagaagctg tcatggtctg tccagaagtg atcggcggat
     7921 taccaattcc tagagatccc gctgaaatca ttggtggaaa tggattcgat gtgtggaaag
     7981 atcaagcaaa agtgtatgga cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg
     8041 cgcgatcaaa gcctatcaaa aattgcagga aaaacacatt gatctagtca tcatgaagga
     8101 aaaaagccct tcatgcggaa cccattcgat ttatgacggg agtttttccg gaataaaaaa
     8161 aaatggtgcc ggagtggcta ctgcttattt tattcagcaa aaaatgactg tgctctctga
     8221 tgaagaatgg ctgaaaacta gaggtgagca gaatggaaat cgaaaagacc aatcgaatga
     8281 acgcgctctt tgaattttat tcgaccttat tgacagaaaa acaaatgaac tacatggaat
     8341 tatattatgc agatgatttt tcattaggtg agatcgcgga agaatacgaa gtaagccgac
     8401 aagcagtata tgacaatatc aagcggacaa gcaagatctt ggaggattat gaaaaaaaac
     8461 ttcatctttt ttctaattat attgttcgag aacaggtatt ggaaaatatg actgcatata
     8521 ttacagataa gtacccggaa gataaaaaac tacttgaata tgtacagcaa attcaagcaa
     8581 tcgaagaata aataaaagga atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct
     8641 ccagcaggcg atgggaaaaa taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga
     8701 aatgatgcgg gaaatccgcc ttgccttact agaagccgat gttaacttgc aagtagtcaa
     8761 agattttact aagcgcgtac gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc
     8821 acctgcacaa caaatcgtaa aaatcgttga tgaagaattg acgatcacac ttggttctga
     8881 aacagcagag ttaaataaat caccaaaaat accaactgtt atcatgatgg ctggtcttca
     8941 aggggcaggt aaaacgacct ttactggtaa attagccaat tatttaaaga aaaatgaaaa
     9001 tgctcgtccg ctcctaatcg caggggacgt atatcgacca gctgcgatcg accaattgaa
     9061 agtattaggt caacagctag acgttcctgt atttgatatg ggaactgaag tcagcccggt
     9121 agagatcgtc cgtcaaggga tggagttagc aaaagaaaag aaaaacgact atgtattgat
     9181 cgatacggca ggacgtctgc atatcgatga aacattgatg gatgagttga aacaaatcaa
     9241 agaattgacg caaccaaatg agattttgct tgttgtcgat gccatgactg gtcaagatac
     9301 cgtcaacgta gctgatagct tcaaccagca attaggtatt acaggggtcg tcatcactaa
     9361 acttgatggg gatactcgag gcggggcagc actatcgatc cgctcagtga caggcgcacc
     9421 aatcaaattc atcggttctg gtgaaaaatt gactgactta gaagtattcc acccagatcg
     9481 tatggctagc cgtatccttg gtatggggga tatgctgaca ttgattgaaa aagcgcagca
     9541 agactatgac gagaaaaaag cggaagaact tgcacagaaa atgcgggaaa attcattcga
     9601 tttcaatgac tttattgaac agcttgatca agtgatgggt atgggcccac tggaagatct
     9661 aatcaaaatg atcccaggaa tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc
     9721 aaaagatgtt gaacgcaaaa aagcgatggt ttattctatg acgccagcag aaagagcaaa
     9781 tcctgatctg ttgaacccaa gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt
     9841 tgttgaagtg aatcgaatga tcaaacaatt caaggaatca agaaaaatga tgcagcaaat
     9901 gtccaaaggg gatatgaaca tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg
     9961 aaaactaggc aaaatggcga tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa
    10021 acggaaataa gatgaaaaaa acagcttcgg tacagactga aaatgtctac tgccggagct
    10081 tttctatcag caatttttat tctttactaa tacaattact ctaaacgaag aggtggcaca
    10141 gatgagatgt ccgtggagtg aacaaacaga aagtatgcgg caatatcatg atactgtctg
    10201 gggtgttcct gaatatgatg accaaaagct gttccgaaaa ttgatgcttg atattaatca
    10261 agccggattg agctggcaga cgattttaaa taaaagtgaa gcattcgatg aagcatatga
    10321 tcgattcgat attaaaaaag tcgcaaatta tggagaaaca aaaatcagtg aactaatgga
    10381 aaacaaagga attattcgta accgaagaaa aatcgaagca gccgtccaaa acgccaaagc
    10441 agtcttgaaa attcaagaag aaatcggcag tttttcagag tatctttggt cgttttctaa
    10501 tggaaaaatc gttgattctt cttatcattc acaagaagaa gtcccaacaa caagtcctct
    10561 ttcagatgaa ttagcaaaag atctaaagaa aagaggattt aaatttatcg gaagcacaac
    10621 aatctatgct tttttagaag ctgtcgggat catcaatgat caccttgaca gttgtttccg
    10681 caaagaagag gtcgtacgta tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt
    10741 ttatggtgct ataagtttag atggctattt ggcaacgaaa acggatgatc ttcaatggct
    10801 ttttgacact ccaacaggta agcaaaccac ttatgaagct ttttatgaaa caatcgatac
    10861 gaccatcatg ggcagaaaaa cttatcagga agcaaaaaaa tatttggaga ccgaagcaat
    10921 ttatccagag aaaaagaatt tcgttttttc cacccacgca caattacaat tgccagatgc
    10981 tgaggtcgta aacgaagatc ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa
    11041 agatatctgg gttgtgggtg gcggtcgatt gatcaaaccg ctattggaac atcaaatgat
    11101 tgatgaatgg tatatccaga ttacccctgt attattaggg gacgggattc ctttattcca
    11161 aaaaggaaca tatgaagcgc gttttgaaat gctagacacg acacgattcg gtgaatttat
    11221 cgaattgcat tatgtacgaa agtagaagta aataaaataa aaaaggcaac tatatgcaga
    11281 aatgtcctgt acatagttgc cttttttatt accgttatgc tttttactct gttaatttgt
    11341 tagaaaaatc tagatacgca tctaaaatcg tttggaagaa acttaatgtt ccttcaacga
    11401 tattaccatt ttcatcaatt agattcgcaa cgtttccgat atatgcttcc ggttgctgca
    11461 aggttggcac attcaaaaag acaagtgatt gtcgtagatg gtggtttgcg ccaaagccgc
    11521 cgatcccacc tggtgatgca gtaacgacta aacctggttt atgatcccaa acgctgtgtc
    11581 cataaggtct tgagcctaca tctaaagcat ttttcaatac tgctggcaca gaacggttgt
    11641 attcaggagt aacgaaaacg acaccgtcta gtcccctcac ttcctcacga aaacgagtcc
    11701 attcagcagg agcctgttct ggagtttcga gatcctcatt gtaaaatggc agatcatcga
    11761 tttttacaaa tacactttcg tacccttcag gaagcaattt cgcaaaagct tctgctactt
    11821 ttttgttgta agaatctttt cttaaactac caataaaaaa tccaattttt tttgtcatac
    11881 gatttttcct ccttcaaact atctataaca atcttacaaa aaataagtaa ctggagcaaa
    11941 taaaaacact tactgacaaa agctacatag aagatagatt acttattttt aacaaaaaag
    12001 aagtctaaaa tcttctattt cctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa
    12061 agctttacag ggtaaaaaaa aactgttaca ctacatcttg tgaataaaac aatggaggtg
    12121 gaaataaata atggcagtta aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt
    12181 ttaccgtatc gtcgtagctg attcacgttc tcctcgtgat ggacgtttca tcgaaactgt
    12241 aggtacttac aatcctttga aagaccctgc agaagtagtt ttaaaagaag acttagttct
    12301 tgactggtta tcaaaaggtg cacaaccttc tgacactgta cgtaacatcc tttcaaaaga
    12361 aggcgttatg caaaaacacc acgaagctaa attctcaaag aaataaggtg accggatatg
    12421 aaagatttaa gcgacttagt cttaacaatc gttcgtccgc tagtcactta tcctgatcaa
    12481 gtcaagttag acgtcgtaga gtcgaaagac ttttacgagt acaatctaac agtggctcct
    12541 gaagatattg gccgtatcat tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc
    12601 gtttacggtg ttcggatcaa tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag
    12661 gaaaagtaaa taaacgtgct gtactcgaat tttcgagtgc agcttttttg tttttttatt
    12721 aattgaagaa atgattattt ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg
    12781 agtgaacagc caatgagaaa gaaaatgtta tttattccat ttgctctatt gttaagcgct
    12841 tgtagttcgg ttactcaaga atcagacaat acacatctat caagcagtat atctgaaact
    12901 gttaccagtc cagaaaaaag tagtaccaaa acggctacca ccactgaaca aacaatggct
    12961 acctcaaata atgagaaaaa gactgcttta gaccagttga aagaacaaca gccaaatgtt
    13021 cccatgcctc tagatgtacc agtctcttca ggctatctca atatcgcagc gacacataca
    13081 aagcaaggtt attctatttt atattacaga acagatcgtc ccctcgggtt gaatgctgac
    13141 gaattgaatc aagaaacgcc tattgcaacc tatctatatc aatatgggtt tgcttctagt
    13201 caagaaacaa tccaagtttt gcagcccttt gagatcgaca caaatggtca gcaagtggac
    13261 ttaggttctc gaatcacagg gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg
    13321 caagaaggaa actggcgtat tcgaatccgt gggaataata tagaaggcca agatccctta
    13381 ctattagcta aagaaatcgt agcttatttg gaagaaaaca gtctaccagc acctgaacaa
    13441 tttggtaaaa ttactgttga tatgggtgat acgacgaatc gagccgtaga agtaagctgg
    13501 caagaaccga aaaatgccta tacgatcact catcaagatc ctatgtctgc gttgaagatg
    13561 gcagtttcta tgaagaggtt gtgaaatcag cgcgctgatc tgagcccatc atttaactcc
    13621 aagtcacagg aagtaatcaa aaatagcacg ccgcattttt gcataatttt ggcttaatac
    13681 cttaaaagaa aactagaatt gcctcttcac acatgctaaa ataaaacaga caaaaaagaa
    13741 atggggatat aagttgactg aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat
    13801 caaaggcgaa gtccgtgtta tctcaacaac ggatttccca gaagaacgtt acaaaaaagg
    13861 aacggtgtta acactattcc aagacggaaa agcacctgtg gaattaacag tcaaaagtca
    13921 tcgcaaacat aaaaattttg acttattgag ttttgaagga catccttcta tcaatgatgt
    13981 ggaaaaatat cgggatggca tattaaaagt gtcaaaagac aactctgtag atctagctga
    14041 aaatgaattc tattaccatg agatcatcgg tctgcatgta ttagaagatg gaactgagtt
    14101 aggtaaagta aaagaaatct tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc
    14161 gaaaaaagct gatatattgc ttccatatat cgcttctgtc gtcaaagaag tcgatttaga
    14221 agctggagtg gtccgtgtag aaattccaga aggactgatt gacgatgaag attgatgtat
    14281 tgactttatt tccaagaatg tttgaaggtc ctatggggga atccatcatc ggtaaggctg
    14341 tagataaagg attattagat atcaatatct ctaacttccg cgattattca gataacaaac
    14401 atcagacagt agatgattat ccatacggcg gtggagcagg tatgctgctc aaagtccagc
    14461 ccatctatga taacatccaa gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa
    14521 ttcttcttga cccagctggt aaacgattcg atcagaaaat ggcagaagaa ttttcacaag
    14581 aagaacactt agtattcatt tgtggtcatt atgagggata tgatgaacgt atccgcacat
    14641 tagtgacaga tgaagtttcc ttaggagatt atgtccttac tgggggagaa ttaggtgcga
    14701 tggtcatgat cgatgcaaca gttcggcttt tgccagatgt gttagggaat cagacttcag
    14761 ctcaaacgga ttcttattca accggtttat tggaacatcc ccaatatact cgcccggcag
    14821 aatataaagg gatgaaagta ccagaagtat tgacaaatgg aaatcataaa ttgattgaag
    14881 aatggcaatt aaaagaatca ctaagaagga cctatcaacg tcggcctgat cttttggaaa
    14941 cacttgaatg gacacctcaa atgacgaaat ttttagaaga aatcaagaaa gaagaacaag
    15001 aaaaaacagc agatgaagcc aagtgacttt ttctaaaata ttctttacag taggttgata
    15061 atatgttagt attttatggt gagtgcaaaa gcacttaact attacgatat tccgctatga
    15121 gaaaagctca taagaatatt tggaataagg agaagaaaac catgaatcca ttaatcgaag
    15181 aattaacaaa agaacaatta cgttctgaca tcccagcgtt ccgccctggt gacactgtgc
    15241 gtgttcacgc aaaagttgtt gaaggtactc gtgaacgtat ccagttattt gaaggtgttg
    15301 ttatcaaacg ccgcggtgct ggaatcagcg aaacttatac agtacgtaaa gtttctaacg
    15361 gagtgggcgt tgaacgtaca ttcccattgc atacaccacg tgttgcaaaa atcgaagtag
    15421 ttcgctacgg taaagtacgt cgtgcaaaat tgtactacct acgtgcatta cacggaaaag
    15481 ctgctcgtat caaagaaatc cgtcgttaat cattgttatc agactgagaa agaacccttg
    15541 gtattcaagg gttctttttt cttagcatgt aatttgaaca ccctgatcca gtttttttct
    15601 ttaattattg gtaggggaga ataatggatt agaataaatc tacctataag tagtagtaaa
    15661 aaaaagagca ctatgataat atctttctta agagtaaccg ctttaataaa aaatccagaa
    15721 tattctaaca taaatggagt attcttagaa tcaaaaggag aaagaagatg gtttatactt
    15781 atacggagca agaaaaaatg aaagtttgag acacattcat gaatgatgga aaagtaaaac
    15841 aagtaccaag ttcaacaaaa aagaaaaaca tcctattgaa agaagtcttg aaacgctttg
    15901 accatggagt gacttataca gaaacagagg ttaattcgat actgctgaac gtattttcta
    15961 gtggcgatta tgtcgaacaa agacgttatc taatcacatt tggctttttc aaaagaagtt
    16021 cagacggtcg ggcatatcag atgatgggaa ttgaaaatta gaagttttaa tttatactca
    16081 ttgaaaaaag ttcaagtatg cgatattggt tctacaccgc atacttgaac tttttttgtc
    16141 atctgtatct ataatacaaa gccaagaacg ttattcaaaa tatggatagc tatgataaaa
    16201 gctaatgagc gattcgcagt taaataagca atcgtcagta aaatcgttcc aggagcgtac
    16261 atgaaaaaat caattggatg cgttacatga ataaagataa ttctctttta tttgtacgaa
    16321 taaataccaa aacgtacctc ctaaaattag attcaaagaa gatagcaaag aggaaaaaga
    16381 tagttctgca gcagctatag cggcatgtgg attgctagaa ctttccaaac aactgcctgt
    16441 ttcagatcct cgtcatttcg attacgaaga gatagcaatc aaaatcttgg aagaattaca
    16501 gaaaaactat acaacgaaac gagttaacgg atcaaacggt ctgcttctcc atgccgttta
    16561 tgataaaaac agcttaaaag gtgtagatga atgtgtgatc tggggcgatt acttttatgt
    16621 agaaggaatc actcgtctag ctaaaacatg gtactgttac tggtgatgta taagagaaga
    16681 ggaggattca tataatgaag cgatggaaaa aaatgatgat tggatcaata gttttaggaa
    16741 tgtcactcgt atttggtgct tgtggtaatc aagaagacag tagtgaagaa tcagcaaatg
    16801 aaattaccgt ttcgacatgg aattatgaaa caacacctga attcaaagcg ctctttgaag
    16861 cattcgaaaa gaaaacggga atcaaagtga aagcagtaga tattgcttca gatgattatg
    16921 atacgaaact caccacgatg ctttcttctg gagacacgac agatgtattg acgatgaaaa
    16981 atcttttgtc gtattcaaat tatgctttac gagatcagtt agtcgatcaa acagaacgaa
    17041 ttagagaatt agacactgat gctgctgaag aaacatatga aatgtatgat atcgatggaa
    17101 aaacatatgc attgccatat cgaacggact tttgggtact atattacaat aagaaaatgt
    17161 ttgatgatgc aggaatcgaa tatccaaaaa atctaacttg ggacgaatat gaagatttag
    17221 caaaaaaact tagtaaaaat gacggacaag tttacggagc atatcaacat atctggcgtt
    17281 cgacaatcca agctattgca gctgctcaaa acgaggcgaa tcttgttgaa ccagattatc
    17341 aatatatgac tgattattat gatcgagcat tgaggatgca aaaagaaggc gcgcagatgg
    17401 attttggcac ggctaaatca acgaaagtaa cctatcagtc tcaatttgaa gaacaaaaag
    17461 cagcaatgat gtacatggga acttggtata tggctggcat actcgcaaac aaagaagcaa
    17521 gtaagacaga agtagaatgg ggaattacag ctattcctca gaagaaaaaa ggagaatcgg
    17581 tcacgacgtt tggctcacca acagcatttg ctgtcaataa aaactcaaag aaacaaaaag
    17641 cggcgcaaga atttattgaa tttgcagcca gtgaagaagg agcaaaagta ttagcaggag
    17701 taggagtagt tccttcatat cgtacggatg agattgatca gctttatttt aatctcgctg
    17761 gaatgccaac ggatgaaatt tctaaaaaag ctttttctcc tgatgaaatc aaacttgaat
    17821 ttccgattga tacgtatggg cctgcaatcg ataagatttt acaagaagaa tatgacttag
    17881 ttttggttgg agatgaaacg ccggaaaaag gaacggtaaa tatggagaaa cgtgtagctg
    17941 cggaaaaaga ataatcatga aaggagagaa gccaagagat aaaacactct tggtttcgtc
    18001 atcgaaatgg agaatagtat aaataagaaa gctacaaatc atttgcgtag aaaacgaacg
    18061 tggatcgctt attcgtttat cgccccgaat ttcattggtt ttttcgtttt tacattaata
    18121 ccaatcctgt tttcgcttgt actagcattt atgaaatggg attctttttc aacgccagaa
    18181 tttgctggac tagataactt tcgtaaaatg gccaacgatg agacattttg gatttctttg
    18241 aaaaatactt ttttatatac cgctgctgta gtgcctggca cacttgtttg ttcgttaggg
    18301 ctagctttac tactaaatca gaaaattaga gggatgaagc tttttcgtac gatatttttc
    18361 tttccgtatg ttacttcctt agtagcaatt gctgttgttt ggaatatgtt gtttcatcca
    18421 acagtgggac ctattaatat ctttttaaga cgatttattg aacatcctcc aggttggact
    18481 tcaagttcaa attgggcgct ttgggcaatt gtaattgtca gtatttggcg agggatgggt
    18541 tattacatga ttctatacct tgcaggacta caaagtatcc aaaaagaact atatgaagcg
    18601 tcttcgctag atggagcaaa ccgttggaaa caatttttga atgtgacatt accttcgttg
    18661 agaccaacaa ccttctttgt aacgatcatg cttgtcatca attgtttcaa ggtgtttgac
    18721 cttgtgcaag tgatgacgga tggcggccct ggtcgagcga caaatgtgct ggtttaccaa
    18781 atctacaatg aagcattcaa aaaatttgat tttggttatg cttcagctat ttcacttgtt
    18841 ttgttcgtaa ttgttttggg cgttacggtt gttcaatttt cttggaataa gcgtcgtact
    18901 taggaggtgt gatatggaag agagtgttcg aaatgaaaga aaaaaagcaa aaattcgttc
    18961 aaaaaacatg ccctttattc aatggttggg tatgattctg ctgattgtat tagctttatt
    19021 gacgatcatt ccttttttat ggatggtttc tgcttcattc aaagcaaata atgaagtgtt
    19081 aacgattccg attcaatgga tccctaaaac ttggcattta gagaattatc tggttatttg
    19141 gtctcgtatt cctttagtga cattttttaa gaatacagct tttttaagcg ttgtgatcac
    19201 gttgattcag ttgtttactt ctagttttgc tgtttacggg ttttctgaac taaattttaa
    19261 agggcgcgat attttatttt tagcatatat cggcacgatt gctgtccctt ggcagtctta
    19321 tatgatcccg cagttcatta tgatgagaaa agtgggttta acagatacgt tgtggtcgtt
    19381 ggtgctatta caagcgttca atgcttttgg tgtgttcttg ttgaagcaat attacagtag
    19441 tatcccagat tctttatgtg agagtgcgcg gatcgatggc ttatcagagt gggaaatcta
    19501 tcgcaagatc attttacctc ttacaaaacc ggcgattgcc agtttgacga tcatcacatt
    19561 cgttaataca tggaacgatt atatggggcc attcatttat ttgtcttcta cggaaaataa
    19621 aacaatccag ttagggttga aaatgtttat tgggctattt gatgcagagt acgcattaat
    19681 catggctgcc tcagttgttt ctgttcttcc tgttgctttt atatttttag cgatgcaaaa
    19741 atattttgta gaagggatcg cttcatcagg aatgaaggaa taggaggtga ttatgaaaga
    19801 gcagcgtttt gacaaaaatg tttatatgga attcttttat tggttgtatc aatcattggc
    19861 aagtagcctt tgtttttggt gtgtcaatat cttgtatata gcagctgcgt tccttttgtc
    19921 gatagatgga aggaatgtct tttcctttat tttttcttta ctttttattg gtccaggttg
    19981 catcgtgatg ataggtatga cagaagaatt agcaaaagaa aaaagttttt caccagtacg
    20041 tttgttcata aagacgtttc gccaattttg gctaaaggga tttttttatt ggctatttgc
    20101 ttggatagtt agtgtgataa tgatttttga ttgtttcttt tttatacgtt tttcttatgg
    20161 aaaatggttg attccgttgt ttgttttact tgcttgtttt acttgcttgt ttatcagttt
    20221 cctttagcat caactgctgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag
    20281 ttctacggat agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt
    20341 tactattgac aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag
    20401 gtccttctat cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg
    20461 atctgtagac tttataaatt gaaactttca attaagaatg acagtttttt atgtaaaaac
    20521 tgtcattctt tttcattttt tgaaacatat ggctaaacaa atgaaataaa acatgctata
    20581 cttttgaatg aaacaggttt agaaactgta tcacttattt gtgattattt ctaactaata
    20641 attaaaaata aagcataaaa aggacgatgt tcaatggctg aaaaaatgaa acaaggttcg
    20701 aaatctgtag tagaaagttt gattaatcat catgttgatt atgtattcgg tataccaggt
    20761 gcaaaaatcg atggtgtatt taatgaatta gaggatcaag gtcctgaatt aatcgtgact
    20821 cgtcacgaac aaaatgctgc atttatggca caagcaatcg gacgtattac aggagagcca
    20881 ggagtagtta tcgcaacaag tggtcctggt gctagtaact tagctacagg tttggtaaca
    20941 gcgacagcag aaggtgaccc agttttagca attgccggac aagtaaaacg aagcgatcta
    21001 ttgaagttga cccatcaaag catggataat gcagcactgt tccagccaat cacaaaatac
    21061 agtgcagaaa tccaagatcc agaaacaatt tcagaagtga ttgccaatgc ttatcgtatg
    21121 gctaagagtt caaaaaaagg cgcgagcttt atcagtatcc cgcaagatgt agtggatgca
    21181 cctgtccaag gtaatgtcat caagccattg agcgatccta aattaggttc tgcttctgca
    21241 gatgatatcc gttacctagc tgaacgcatt agagaagcaa aactaccggt actattagta
    21301 ggtatgcgag gatcaagtga aaaagaaacg ttagccatca ggcaattagt tgaaaagaca
    21361 gcattgcctg ttgtagagac attccaagca gctggagtga tctcacgtga attagaagcg
    21421 catttctttg gtcgtgtggg tttatttaga aaccaaccag gagatatgct tttgaaacga
    21481 agtgatctag ttattgcaat tggctatgat ccaatcgaat atgaagcaag aaactggaat
    21541 gcggaaaaag atgcgcggat cattgtgatc gatgaagcgc cagctgaaat cgatcctttt
    21601 atgcagcctg aaagagaatt gatcggtgat atctcagcca ctcttgattt attgacaggt
    21661 tcattagagc ctcaacaagt gtcagaagat gcaaaagaat atttagcatc tcttcaagca
    21721 aaattaacgg agcgggacat tgttcaatca aaaggagaag caggtatctt gcatccttta
    21781 gaagttatta acacgcttca gtcaaaagta acagatgata tgactgttac cgtagatgta
    21841 ggtagtcatt atatttggat ggcacgccac tttagaagtt atgaacctcg tcatttgtta
    21901 ttcagtaatg gtatgcaaac gcttggtgtt gcattgccat gggcgatttc tgctgcattg
    21961 gtgcgtccaa atacacagat cgtatcagtt tccggcgatg ggggattttt attctctgcc
    22021 caggatttag aaacggcggt acgtaaaaaa ttgaatatcg ttcatttgat ttggaatgat
    22081 ggacactaca atatggtaga gttccaagaa aaaatgaaat atcagcgggc gtcaggtgta
    22141 gactttggtc cagttgattt tgtgaaatat gcagaagctt ttggcgctaa aggaatccga
    22201 gctacaagtg tagaggaatt agaaaaagct ttagaagaag gatttgcgac agaaggaccc
    22261 gtaattattg atattccgat tgattaccgt gataatgaga aattgggaga aacaatctta
    22321 ccagatcaat tctattaagg aagtgtcgac atgactgaaa aaatcttata ccagcacggg
    22381 acattaggag ctttgatggc cggcttgatg gatggaacag aaacgattgc tcatatatta
    22441 gaaaaaggaa ctctgggatt gggaacattg catgggcttg atggtgaagt catcttttta
    22501 gatggcgtag cttatcaagg aagatcagat ggctcagttg cccaattaga tggaagtgaa
    22561 cttaccccct atgcagcaat tacagatttt acgccagata ctagtttttc tgtctcaaaa
    22621 actgcagatg gagaacaatt gaaaaaagac atattagtaa gagaagccgg ggaaaaccta
    22681 tttttggcag tgaagataac tggattattc aaaaatatgc acatccgtat catgccgaag
    22741 caagaaaaac cttacagaag actagcaaaa atttcagagt ctcaaccaga attccaacaa
    22801 agcaatgtcc aaggaacatt agtcgggttc tttacgcctg aattattcca aggagttgct
    22861 gcagcgggat ttcacctgca ttttatcgat gatacacata catttggcgg acatgtaatg
    22921 gattttgaag tggctgaagg aaaagttgag attagccgca tctcgtccct tgtacagcat
    22981 tttccagttg atgatccgac ttttgttcac gaaacgattg attatgctga tttagcagca
    23041 gaaatccaac aagcagaata gaaaaagaca gcgagatgcg ttcaaggtga ttaacctgac
    23101 gtatctcgtt tttttgagga gaaaacctag cgtttacaaa aaaactgagc tataatcttc
    23161 tccatagatc aaaaaggagc ggtttttatc atgtggacag aaaaacagaa aaaagatgca
    23221 tacgaaattt tattattaca gcaacaagga ttattagaag cagaagataa ctggttagca
    23281 aatttagcaa attcatctgc attgttgaat gagactttgc ctgagactgt ctttgcagga
    23341 tattatttat tcgatggtaa tgaattgatt ttaggaccgt tccaagggcg agtttcttgc
    23401 acacgtatca agatgggaaa aggagtttgt ggagaatcag ctgaaaaaca agaaacattg
    23461 atcgttgatg atgtcaaaac ccatgcaaat tacatttcct gcgattcagc cgcacaatca
    23521 gaaatcgtag tgccaatggt aaaagaaggt aatttaatcg gtgttttaga tatcgattgc
    23581 ggagtaacga aagggtatga tgaaatcgat caagcatttc tagaaaaata tgtagatctt
    23641 ttattagcaa attttaatat aaatgctttt tcatttatta ataactaaaa tcgtctattg
    23701 aaacaaaaaa gaagagaaat caagaataaa aagagccgga aagacagtgg gcatttctgt
    23761 ttttcggttt ttttattttt ttataaaatc acaagtgtta ttgattttca taatcatatt
    23821 ttaatgttat tatcatttta aataatgaaa aaacattaag gatggatgaa atatgaataa
    23881 cgaaactatc attttaggaa aaaaatatat ttgccaacct attggcttga aacaaaaagt
    23941 gattggagaa gtaatcagta aattagaaaa ttgtgttgtg atctgcgtag acgaatatca
    24001 tgacgtcgat cgcaatgaaa tattagaaaa atgcggaaaa gtagtggcaa aatatactca
    24061 cgtttatgag ttggaaacaa cagaatatct atataactat agcaacaaat atgaacatac
    24121 tttagtttca taaagattta aataaagtgc cttcaaaagc gagaagacca agcttttgaa
    24181 ggcactttat ttagttggca gtgattgttc atgatttttg atttattcaa aaggttcgcc
    24241 tagagaatct gtctctgtaa cgaggcctgg tggagaaact cgataaaaac ctatactgcc
    24301 agaactgtcc tattttcgga tagacaaact agtagtttta aaaagatcat ccgatccaat
    24361 catttcaaaa aatgcaaaac tgatatcagg atcatttagc tcaggcttgt tatcgtaaag
    24421 catttgtaaa ggttgcattt agttaggagt aaacgcgaaa ctatcatcat tatttgctga
    24481 agaagatgaa gaagctaatt cagagtttgt ttgaaataaa ggagacgtgc tgacagtttc
    24541 tttaccctgt tttttgcaga ggtagaaact tttatatcgg aagtttctac cggagaattt
    24601 ttctcatttg tagaaattgt tgaatcgata ctattcgaaa tttgcgtatc tgaaggtatg
    24661 ttctttgatg cagaagtccc acaagcagta agtaacaata aatttgataa actgataaac
    24721 agaattcttt tcattatgta cacactcctt atagtatcgt ttagcataca cctatgctca
    24781 gtattaggca aaatcaatgc aaaactatca agtcttttat agtatctatt agtcttagta
    24841 atacatatat ggagagggtg atatcccagt tcaaaccaga tacattggtt accatctgta
    24901 ttaacgatta tgcctctaaa cgcttttttt atgaaaaaat ttataagtga aaacgtaggt
    24961 atgatattat ctagaggtaa tttttttggg tatttaaata gttgctagga ggatagcttt
    25021 tggattttta cagtaatttt atcttaataa tagcaatatt attacttcta aatatttggt
    25081 tttttgataa gagtagaaat gcagggatag gttttagaac caaacgaagt acgtcttctg
    25141 aaaaaaagtg ggtatattca cagactattt tttacggagg ggttatttca atcagtttac
    25201 tttcttcaac actttattct tttaatgtta tagacgtttc catgtcaaat tttatatcta
    25261 ttattggaat ccttatttct gcaattatta cacaactact tcttgtgttt gaagagaagt
    25321 caaaaaataa ttaaagcaat tatgcctttt agtacaggaa ttattacttc ttacaaatgt
    25381 atagcgaatg tgaagcctgc tgttttaatt gttctagaaa aacttttgag tgaacaatta
    25441 ttttatgtta ggatgaatta atttctctag agtttata
//
LOCUS       DAZKNV010000038        25129 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000038 DAZKNV010000000
VERSION     DAZKNV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.038"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            12..84
                     /locus_tag="ACG8M1_001769"
     tRNA            12..84
                     /locus_tag="ACG8M1_001769"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="ACG8M1_001770"
     tRNA            88..160
                     /locus_tag="ACG8M1_001770"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="ACG8M1_001771"
     tRNA            168..249
                     /locus_tag="ACG8M1_001771"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="ACG8M1_001772"
     tRNA            267..339
                     /locus_tag="ACG8M1_001772"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="ACG8M1_001773"
     tRNA            351..422
                     /locus_tag="ACG8M1_001773"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="ACG8M1_001774"
     tRNA            439..524
                     /locus_tag="ACG8M1_001774"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="ACG8M1_001775"
     tRNA            535..608
                     /locus_tag="ACG8M1_001775"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="ACG8M1_001776"
     tRNA            618..691
                     /locus_tag="ACG8M1_001776"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="ACG8M1_001777"
     tRNA            711..783
                     /locus_tag="ACG8M1_001777"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="ACG8M1_001778"
     tRNA            811..884
                     /locus_tag="ACG8M1_001778"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="ACG8M1_001779"
     tRNA            898..971
                     /locus_tag="ACG8M1_001779"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="ACG8M1_001780"
     tRNA            995..1084
                     /locus_tag="ACG8M1_001780"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="ACG8M1_001781"
     tRNA            1097..1170
                     /locus_tag="ACG8M1_001781"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="ACG8M1_001782"
     tRNA            1189..1264
                     /locus_tag="ACG8M1_001782"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="ACG8M1_001783"
     tRNA            1266..1336
                     /locus_tag="ACG8M1_001783"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="ACG8M1_001784"
     tRNA            1350..1423
                     /locus_tag="ACG8M1_001784"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="ACG8M1_001785"
     tRNA            1448..1535
                     /locus_tag="ACG8M1_001785"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="ACG8M1_001786"
     tRNA            1557..1628
                     /locus_tag="ACG8M1_001786"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="ACG8M1_001787"
     tRNA            1651..1740
                     /locus_tag="ACG8M1_001787"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="ACG8M1_001788"
     tRNA            1753..1826
                     /locus_tag="ACG8M1_001788"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="ACG8M1_001789"
     tRNA            1845..1917
                     /locus_tag="ACG8M1_001789"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="ACG8M1_001790"
     tRNA            1921..1993
                     /locus_tag="ACG8M1_001790"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="ACG8M1_001791"
     tRNA            1998..2068
                     /locus_tag="ACG8M1_001791"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="ACG8M1_001792"
     tRNA            2081..2154
                     /locus_tag="ACG8M1_001792"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="ACG8M1_001793"
     tRNA            2166..2237
                     /locus_tag="ACG8M1_001793"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /gene="metK"
                     /locus_tag="ACG8M1_001794"
     CDS             2503..3696
                     /gene="metK"
                     /locus_tag="ACG8M1_001794"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFQ0422479.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="ACG8M1_001795"
     CDS             3826..5298
                     /locus_tag="ACG8M1_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFQ0422480.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="ACG8M1_001796"
     CDS             5381..6169
                     /locus_tag="ACG8M1_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0422481.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="ACG8M1_001797"
     CDS             complement(6236..6904)
                     /locus_tag="ACG8M1_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFQ0422482.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="ACG8M1_001798"
     CDS             7019..8731
                     /locus_tag="ACG8M1_001798"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422483.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10503
                     /locus_tag="ACG8M1_001799"
     CDS             8734..10503
                     /locus_tag="ACG8M1_001799"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422484.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10708..11274)
                     /locus_tag="ACG8M1_001800"
     CDS             complement(10708..11274)
                     /locus_tag="ACG8M1_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0422485.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(11274..12230)
                     /locus_tag="ACG8M1_001801"
     CDS             complement(11274..12230)
                     /locus_tag="ACG8M1_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFQ0422486.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(12230..12886)
                     /locus_tag="ACG8M1_001802"
     CDS             complement(12230..12886)
                     /locus_tag="ACG8M1_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFQ0422487.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            13256..15274
                     /locus_tag="ACG8M1_001803"
     CDS             13256..15274
                     /locus_tag="ACG8M1_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0422488.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    15344..15550
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15701..18115
                     /gene="leuS"
                     /locus_tag="ACG8M1_001804"
     CDS             15701..18115
                     /gene="leuS"
                     /locus_tag="ACG8M1_001804"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFQ0422489.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            18463..20016
                     /locus_tag="ACG8M1_001805"
     CDS             18463..20016
                     /locus_tag="ACG8M1_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFQ0422490.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(20397..22181)
                     /locus_tag="ACG8M1_001806"
     CDS             complement(20397..22181)
                     /locus_tag="ACG8M1_001806"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422491.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(22196..23917)
                     /locus_tag="ACG8M1_001807"
     CDS             complement(22196..23917)
                     /locus_tag="ACG8M1_001807"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422492.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            24017..24778
                     /locus_tag="ACG8M1_001808"
     CDS             24017..24778
                     /locus_tag="ACG8M1_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0422493.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         7766 a         4622 c         5357 g         7384 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
    10561 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
    10621 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
    10681 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
    10741 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
    10801 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
    10861 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
    10921 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
    10981 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
    11041 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
    11101 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
    11161 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
    11221 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
    11281 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
    11341 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
    11401 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
    11461 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
    11521 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
    11581 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
    11641 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
    11701 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
    11761 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
    11821 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
    11881 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
    11941 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
    12001 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
    12061 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
    12121 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
    12181 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
    12241 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
    12301 acagccaaga aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca
    12361 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
    12421 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
    12481 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
    12541 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
    12601 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
    12661 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
    12721 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
    12781 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
    12841 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
    12901 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
    12961 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
    13021 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
    13081 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
    13141 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
    13201 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
    13261 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
    13321 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
    13381 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
    13441 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
    13501 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
    13561 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
    13621 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
    13681 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
    13741 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
    13801 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
    13861 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
    13921 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
    13981 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
    14041 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
    14101 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
    14161 ggaaaatggc tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg
    14221 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
    14281 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
    14341 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
    14401 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
    14461 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
    14521 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
    14581 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
    14641 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
    14701 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
    14761 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
    14821 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
    14881 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
    14941 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
    15001 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
    15061 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
    15121 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
    15181 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
    15241 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
    15301 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
    15361 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
    15421 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
    15481 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
    15541 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
    15601 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
    15661 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
    15721 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
    15781 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
    15841 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
    15901 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
    15961 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
    16021 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
    16081 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
    16141 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
    16201 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
    16261 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
    16321 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
    16381 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
    16441 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
    16501 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
    16561 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
    16621 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
    16681 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
    16741 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
    16801 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
    16861 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
    16921 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
    16981 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
    17041 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
    17101 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
    17161 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
    17221 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
    17281 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
    17341 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
    17401 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
    17461 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
    17521 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
    17581 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
    17641 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
    17701 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
    17761 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
    17821 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
    17881 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
    17941 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
    18001 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
    18061 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
    18121 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
    18181 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
    18241 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
    18301 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
    18361 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
    18421 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
    18481 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
    18541 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
    18601 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
    18661 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
    18721 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
    18781 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
    18841 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
    18901 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
    18961 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
    19021 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
    19081 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
    19141 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
    19201 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
    19261 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
    19321 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
    19381 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
    19441 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
    19501 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
    19561 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
    19621 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
    19681 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
    19741 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
    19801 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
    19861 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
    19921 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
    19981 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    20041 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    20101 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    20161 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    20221 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    20281 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    20341 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    20401 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    20461 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    20521 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    20581 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    20641 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    20701 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    20761 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    20821 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    20881 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    20941 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    21001 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    21061 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    21121 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    21181 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    21241 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    21301 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    21361 aaggcgagtt gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca
    21421 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    21481 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    21541 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    21601 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    21661 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    21721 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    21781 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    21841 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    21901 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    21961 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    22021 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    22081 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    22141 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    22201 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    22261 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    22321 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    22381 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    22441 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    22501 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    22561 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    22621 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    22681 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    22741 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    22801 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    22861 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    22921 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    22981 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    23041 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    23101 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    23161 aagcataaac gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt
    23221 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    23281 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    23341 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    23401 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    23461 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    23521 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    23581 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    23641 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    23701 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    23761 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    23821 gtacacctaa tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc
    23881 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    23941 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    24001 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    24061 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    24121 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    24181 tttttataga aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt
    24241 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    24301 gatgaaacaa aaacaaaaag agataaggga gcgaaaaaaa cagttgaaat tgatgatcga
    24361 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    24421 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    24481 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    24541 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    24601 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    24661 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    24721 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    24781 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    24841 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    24901 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    24961 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    25021 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    25081 gagaatgata aattaaatag gtgcataaaa gcattacact taaaataca
//
LOCUS       DAZKNV010000039        24648 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000039 DAZKNV010000000
VERSION     DAZKNV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.039"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            55..783
                     /gene="purC"
                     /locus_tag="ACG8M1_001809"
     CDS             55..783
                     /gene="purC"
                     /locus_tag="ACG8M1_001809"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFQ0422494.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            783..1037
                     /gene="purS"
                     /locus_tag="ACG8M1_001810"
     CDS             783..1037
                     /gene="purS"
                     /locus_tag="ACG8M1_001810"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFQ0422495.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1039..1710
                     /gene="purQ"
                     /locus_tag="ACG8M1_001811"
     CDS             1039..1710
                     /gene="purQ"
                     /locus_tag="ACG8M1_001811"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFQ0422496.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            1711..3933
                     /gene="purL"
                     /locus_tag="ACG8M1_001812"
     CDS             1711..3933
                     /gene="purL"
                     /locus_tag="ACG8M1_001812"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFQ0422497.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            3918..5357
                     /gene="purF"
                     /locus_tag="ACG8M1_001813"
     CDS             3918..5357
                     /gene="purF"
                     /locus_tag="ACG8M1_001813"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFQ0422498.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            5380..6432
                     /gene="purM"
                     /locus_tag="ACG8M1_001814"
     CDS             5380..6432
                     /gene="purM"
                     /locus_tag="ACG8M1_001814"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFQ0422499.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            6429..7007
                     /gene="purN"
                     /locus_tag="ACG8M1_001815"
     CDS             6429..7007
                     /gene="purN"
                     /locus_tag="ACG8M1_001815"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFQ0422500.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7004..8539
                     /gene="purH"
                     /locus_tag="ACG8M1_001816"
     CDS             7004..8539
                     /gene="purH"
                     /locus_tag="ACG8M1_001816"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFQ0422501.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            8555..9829
                     /gene="purD"
                     /locus_tag="ACG8M1_001817"
     CDS             8555..9829
                     /gene="purD"
                     /locus_tag="ACG8M1_001817"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFQ0422502.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLTGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            9951..10865
                     /locus_tag="ACG8M1_001818"
     CDS             9951..10865
                     /locus_tag="ACG8M1_001818"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFQ0422503.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(10998..12563)
                     /locus_tag="ACG8M1_001819"
     CDS             complement(10998..12563)
                     /locus_tag="ACG8M1_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422504.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(12556..14007)
                     /locus_tag="ACG8M1_001820"
     CDS             complement(12556..14007)
                     /locus_tag="ACG8M1_001820"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0422505.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14021..15037)
                     /locus_tag="ACG8M1_001821"
     CDS             complement(14021..15037)
                     /locus_tag="ACG8M1_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422506.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15257..16345
                     /gene="chvE"
                     /locus_tag="ACG8M1_001822"
     CDS             15257..16345
                     /gene="chvE"
                     /locus_tag="ACG8M1_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0422507.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            16399..17925
                     /gene="mmsA"
                     /locus_tag="ACG8M1_001823"
     CDS             16399..17925
                     /gene="mmsA"
                     /locus_tag="ACG8M1_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0422508.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            17927..19132
                     /gene="mmsB"
                     /locus_tag="ACG8M1_001824"
     CDS             17927..19132
                     /gene="mmsB"
                     /locus_tag="ACG8M1_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFQ0422509.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            19389..20366
                     /gene="guaC"
                     /locus_tag="ACG8M1_001825"
     CDS             19389..20366
                     /gene="guaC"
                     /locus_tag="ACG8M1_001825"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFQ0422510.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            20630..22054
                     /locus_tag="ACG8M1_001826"
     CDS             20630..22054
                     /locus_tag="ACG8M1_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFQ0422511.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(22096..22353)
                     /locus_tag="ACG8M1_001827"
     CDS             complement(22096..22353)
                     /locus_tag="ACG8M1_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422512.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            22515..23624
                     /gene="pdhA"
                     /locus_tag="ACG8M1_001828"
     CDS             22515..23624
                     /gene="pdhA"
                     /locus_tag="ACG8M1_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFQ0422513.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            23627..24604
                     /locus_tag="ACG8M1_001829"
     CDS             23627..24604
                     /locus_tag="ACG8M1_001829"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFQ0422514.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         7973 a         4201 c         5574 g         6900 t
ORIGIN      
        1 acgaacaaaa aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag
       61 aagaaagaac ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac
      121 ttgatttgga tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag
      181 ataagtggaa aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact
      241 caaagaggaa taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa
      301 aaagtacaaa ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca
      361 aaacgtctag gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat
      421 aaggatgacc agttggatga tccatttatc aatgaagagc atatctattt cttacaactt
      481 gcaaagccgg aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg
      541 accgaattat ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg
      601 tcgaatggac aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat
      661 gaacgtacga atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc
      721 ccagtctatc aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta
      781 tgatgtattt cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg
      841 aggcagtaaa aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag
      901 gaaaatactt tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa
      961 cgatttgtga caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa
     1021 aaatggagga agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac
     1081 gcagatatgt tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat
     1141 gatgagtcct ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt
     1201 gactatttga gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt
     1261 tttgctgaag aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa
     1321 gcaggacttt tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact
     1381 gtaccattga aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata
     1441 atctatcttc cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa
     1501 gaactaaaaa aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg
     1561 gaaaacattg cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca
     1621 gaacgtgcag tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt
     1681 ttaaaaaact tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa
     1741 gagatcaaga aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg
     1801 atcgaagaag atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt
     1861 atgtggagcg aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact
     1921 agtggacctc atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat
     1981 ggactagcag ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat
     2041 gaaggagctg cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt
     2101 ccaattgcgt tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat
     2161 ttactagaag aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact
     2221 gtaggcggcg aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg
     2281 tgcgtaggtt tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat
     2341 tcgatcatgt atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc
     2401 tcagaagaat ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct
     2461 tttatggaaa agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct
     2521 ctaataggta tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct
     2581 tcaaaagctg gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg
     2641 atgacacctt atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa
     2701 tcaggagagg aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact
     2761 atcggtaaag taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca
     2821 aatctgccag tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa
     2881 ccagctcgaa tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct
     2941 ggacaagtat tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac
     3001 gaaacttatg attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct
     3061 gtgatgaggg ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc
     3121 tatctgtatt tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat
     3181 attattgcta gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct
     3241 gataaaccag aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt
     3301 gaaacgttag gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt
     3361 caagcaatct atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat
     3421 atcactactc aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt
     3481 gcagattttg atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc
     3541 cgaaactttg atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa
     3601 aacggattga ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca
     3661 gaatcagctt tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa
     3721 ttatttgcag aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga
     3781 ttcgaagaaa tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata
     3841 atcgaaattt cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc
     3901 tgggaggatg caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct
     3961 tcggtgtttg gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc
     4021 agcatcgagg acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc
     4081 atcgagattt ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa
     4141 caggagaagc tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca
     4201 atattcagcc ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta
     4261 acttgatcaa tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt
     4321 ctaactccga tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt
     4381 taaataaatt aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga
     4441 cagaaacggc aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac
     4501 aaatgaaaaa cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg
     4561 cacgttttat aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc
     4621 agattgattg ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt
     4681 ttgccagacc agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg
     4741 gacggaattt agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt
     4801 cttctttgtc agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat
     4861 tagtaaaaaa tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc
     4921 aaggtgttcg aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta
     4981 tggtcgatga ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag
     5041 aagcaggggc aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt
     5101 tttacgggat tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg
     5161 aaatcaaaga atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg
     5221 aatcgatcgg tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg
     5281 gagattatcc gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa
     5341 aagtatcgtt cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca
     5401 tacgcaaaag ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag
     5461 catgtcaaaa aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt
     5521 tttgatttat cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg
     5581 gggacgaaat tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc
     5641 gtagcgatgt gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac
     5701 tacttagcaa cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca
     5761 gatggatgtg ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt
     5821 atgtactcag gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct
     5881 caattattga caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc
     5941 gggattcatt caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt
     6001 tctttatcat caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca
     6061 acgaaaatct atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct
     6121 gcacatatca ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg
     6181 gctgcacaaa tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa
     6241 tatggtgaaa ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc
     6301 ctggcagtcg aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa
     6361 aaagtttatg aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga
     6421 gaagaacgat gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag
     6481 ccgattatct atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc
     6541 ctgaagcata tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac
     6601 ctaaagaatt tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa
     6661 aaaagatcga tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga
     6721 aaaattatga taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt
     6781 tgcatggcat acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt
     6841 atatcgacca aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac
     6901 aggaggacac gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc
     6961 cagaagtgat tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat
     7021 cagtgtatca gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt
     7081 agaaatcatt tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct
     7141 ttcgatcgaa gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca
     7201 tcctaaaatc catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat
     7261 ggaaacggaa aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga
     7321 aacgattatg aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg
     7381 tcctagtatg ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc
     7441 atctgactat gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt
     7501 cagacaaaaa ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc
     7561 tcaatactta acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga
     7621 acgaaaacaa acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc
     7681 cgctcttctg gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc
     7741 ttataataat atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc
     7801 aacggtagtc gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt
     7861 agaagcgtgg gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt
     7921 tttgaatcga gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat
     7981 catcattgcc ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat
     8041 ccgattactg acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc
     8101 agtcttaggt ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg
     8161 gaaagtcgtg acaaaacgta agccgactcc agcagaagca aaagcattag tgtttgcttg
     8221 gagagctgtc aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt
     8281 aggaatcgga gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc
     8341 gcaagagaaa atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc
     8401 ggttgaatat gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa
     8461 agaccaagat tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt
     8521 tcggcatttt agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg
     8581 tggtcgtgaa catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta
     8641 ttgtgcgcca ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga
     8701 gcgagatcat tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt
     8761 tggtcctgaa gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa
     8821 aatcttcggt ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca
     8881 attaatggat acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa
     8941 agcagcagcg tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc
     9001 agctgggaaa ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca
     9061 aatgttgaac cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt
     9121 gacaggagaa gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt
     9181 catttcgcaa gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat
     9241 gggtgcttat tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga
     9301 agttttaaaa ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt
     9361 atatgcgggt ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt
     9421 cggtgatcct gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat
     9481 cgatgattta ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt
     9541 aggcgttgtg gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc
     9601 agattttctg gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa
     9661 actagttgga gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga
     9721 agcacagaaa aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg
     9781 tacagatatt ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt
     9841 ccatttataa aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca
     9901 taaagagtgt ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa
     9961 ttcaattagg tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca
    10021 acaatgcgga agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt
    10081 ttgaccatgc agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag
    10141 caaaaacatc aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag
    10201 gtgtgatgtt tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc
    10261 gtctgaaaat ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac
    10321 cagaggaagt agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg
    10381 gcgtcagcaa tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat
    10441 tagtagctaa tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc
    10501 atgtcaatat gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc
    10561 gattgcatga tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg
    10621 tatttatcgg gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta
    10681 aatatcaaac gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata
    10741 tgcaagtgat cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag
    10801 aaattaatat gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac
    10861 cttaaagatt gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga
    10921 aagctgtttt cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat
    10981 tgtacggatt tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct
    11041 tttggagaaa tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa
    11101 ccaatttcaa aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct
    11161 aattcgattc tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa
    11221 atcgtactga aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata
    11281 tctggatcgg taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat
    11341 ttgttccttg aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc
    11401 gaacggtaaa gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga
    11461 accatttctt gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag
    11521 acaaataaac gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg
    11581 atgtacttag atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa
    11641 aagacagaat caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt
    11701 tctttaaggg aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat
    11761 tcgctgattc tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt
    11821 tctaattcat ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca
    11881 agagaatcaa ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt
    11941 tgattctccc taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct
    12001 gtactgactt ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg
    12061 aaagattcag caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc
    12121 aagaaatgat tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc
    12181 tgcaaatcta aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc
    12241 ggtttaagca gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg
    12301 tcgaatccac taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa
    12361 aaagtcaacc cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag
    12421 tcgataattg aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga
    12481 taataagaac caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct
    12541 tcgatgataa aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat
    12601 catcagtgtg acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc
    12661 atttccgtaa taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa
    12721 atctgaatcg atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat
    12781 gccaatcccg ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat
    12841 acgaataaat cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa
    12901 tggctgcaag atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt
    12961 atagtcaagc atatggccgt atcttatttt taagatgact agataatcat tgatatggct
    13021 aatttctttt tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc
    13081 ggaaagtgca tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat
    13141 aatggcatcc aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac
    13201 ttcactttgt gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc
    13261 ttccgccatt ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt
    13321 taaacgaaag ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat
    13381 cggttcttgg acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt
    13441 actaagaact ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt
    13501 ttttttgctt gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag
    13561 ttgagtgaca gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc
    13621 caagatatta ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga
    13681 tacatctaac gtactaattt ctttaagtgt atttgtatta tttttgctct ctcgaatatc
    13741 attcctaagt tcttctagga tattttcctc attgaactca tctacggtta cttggccaga
    13801 aatcaagtcc cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc
    13861 tttttggata tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat
    13921 gctcagtagc aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat
    13981 ctgttttatg cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga
    14041 tgttagctat attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg
    14101 tttttcctgt ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga
    14161 catcaggttt acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat
    14221 cttcttgtcc atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt
    14281 ttatcgcagc taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt
    14341 cggataaatc atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa
    14401 aatcaccgac aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt
    14461 tttttagggt tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg
    14521 gtgtggagtt ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg
    14581 tgaagtgatt gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa
    14641 tgtgggtgac gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag
    14701 ggatccctgc tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag
    14761 taaaaatgat catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt
    14821 cctgattcat gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga
    14881 taattgattc agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa
    14941 cgactagtgg gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga
    15001 ttacaacaag ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt
    15061 gttagtacta tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa
    15121 aatccaagaa acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa
    15181 atcccataaa aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg
    15241 aaatggggga taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt
    15301 gaccgcaagc attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg
    15361 gtatgtagga atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa
    15421 catggtctcg gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa
    15481 agtagaaaat caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt
    15541 gattgcttct atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga
    15601 tatcaaggtg atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc
    15661 gacttttgat aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg
    15721 attgaaagaa ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa
    15781 caacgcacta atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg
    15841 tcagttggtc gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga
    15901 tggttctacg gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac
    15961 attggatgct gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa
    16021 aggcgtgggg tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac
    16081 agttgctggc gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac
    16141 acgtatctta gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt
    16201 tccggtcaat gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc
    16261 aaatacagta tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta
    16321 taaagaatcc gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc
    16381 agagagagga taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa
    16441 ttttctggaa tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat
    16501 gcattgtgcg gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg
    16561 tatccatatg gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa
    16621 gatttgaaag atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt
    16681 ccttatcttt caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg
    16741 attgattggg aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct
    16801 atcgacccga atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata
    16861 gctaaagcat tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg
    16921 aatgaagaag aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta
    16981 acctccatca ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc
    17041 attttacggg atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat
    17101 attattcgcg gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat
    17161 attggagaag tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag
    17221 cgaatcataa acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct
    17281 ggactgatgg gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga
    17341 agcaagatat ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct
    17401 tcagccattg caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat
    17461 ctgctgatgg atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa
    17521 ggagtattag ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt
    17581 ataaaaacaa actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa
    17641 gtcgttttat ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc
    17701 cgtgggatag atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca
    17761 aatggcaaag ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat
    17821 cgaatctata cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat
    17881 caggaagtct tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa
    17941 aaatcttacg gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt
    18001 tggtcgctac agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac
    18061 ggatggtatt ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat
    18121 attagtacta gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt
    18181 agggtcagtg atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat
    18241 gaacccgtgg atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca
    18301 aggtttttgg gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct
    18361 gatgtttcgt ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc
    18421 tgttttccaa aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca
    18481 cttcttgaca ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg
    18541 aacaagaaat cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt
    18601 aaaggcggta tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca
    18661 agggtatccg attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac
    18721 aaataaaaca gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga
    18781 actatcaggg atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat
    18841 ggcagcttta gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg
    18901 tacatcgatg gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg
    18961 cggcattgga acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa
    19021 tggcatgtcg attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt
    19081 gcttttagcc gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc
    19141 cggttattca gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag
    19201 cgaacattca ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt
    19261 ataaattctc tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct
    19321 aaaaaaagcc ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg
    19381 ataatgtaat gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg
    19441 taaatagccg ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc
    19501 cagtagtgcc tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg
    19561 aaaatggtta tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca
    19621 aaaaaatgaa aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat
    19681 attcctttat agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca
    19741 tcgcgcatgg acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc
    19801 ctgaaacttt tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa
    19861 atgcgggcgc agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa
    19921 tcaagacagg ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag
    19981 cagctcgcaa gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat
    20041 ctgtccgttt tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat
    20101 ctcctggcga aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt
    20161 cagaattcca aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca
    20221 aaggatcttt gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt
    20281 atgctggagg aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt
    20341 cgatttttaa tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag
    20401 ttgtcctgca ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt
    20461 ggctggaatt attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg
    20521 tgataagatt tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt
    20581 aaattcggta aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa
    20641 agtagagaaa aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat
    20701 cgaaaacgga aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact
    20761 ttttggtgtg aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt
    20821 actaacgagc aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc
    20881 tgttccaaga atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta
    20941 tgagcaaaaa ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc
    21001 tagcgagatg ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga
    21061 aatcttagcg gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat
    21121 caaacggtat ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac
    21181 tggtggcggt cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg
    21241 gatagctgta gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac
    21301 gcgtttattt gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc
    21361 gatccataaa aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg
    21421 aaaagtgatg agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct
    21481 tccaattatt gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct
    21541 tcctatacga acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt
    21601 aggaaaaaca acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc
    21661 tcaagcgcaa gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa
    21721 tgtatttaat gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa
    21781 aagccgactg ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt
    21841 aggtggttac tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga
    21901 aaaagtagta gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa
    21961 tggaatcaga atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa
    22021 gatgaaaatt ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa
    22081 tataacagct tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata
    22141 taaagaaact aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa
    22201 atgtttgcaa caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt
    22261 ttgattagaa aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt
    22321 attcactaat gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg
    22381 cttttagctt gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt
    22441 gatacagttt tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga
    22501 ggaatgtgtg acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg
    22561 aagtcaatgc agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca
    22621 aagatttagt acctgattta tccgatgatg aactcgttga attaatgact catatggtat
    22681 ggtctcgtgt attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt
    22741 ttgcaccaac tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag
    22801 aagatgttct tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt
    22861 tatctcaagc ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat
    22921 tgaaagctct accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg
    22981 cattaggttt gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg
    23041 gttcatcaca aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg
    23101 ccgtatttta tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg
    23161 cagcaaaaac acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg
    23221 gaatggatcc gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg
    23281 gaaatggacc agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg
    23341 gtgacgatcc aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc
    23401 cattgatccg cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag
    23461 aacaagtcat cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag
    23521 taccaaaaca aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa
    23581 tcaaagaaca aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac
    23641 aatgatccaa gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt
    23701 tgtttttggt gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca
    23761 ggaaaagttc ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg
    23821 attgagtttc ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg
    23881 ttttattttc gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat
    23941 gagcggcact agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac
    24001 accagaattg cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt
    24061 agtgattcct tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa
    24121 cgatccggtt gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc
    24181 ggatgaagct tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt
    24241 atctattatc acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc
    24301 aaaagaaaat atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga
    24361 aacgatcatt caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg
    24421 acaagcgggc gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt
    24481 agaagcccca atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga
    24541 aaatgtctgg ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt
    24601 ttaagaaaag aagggacgaa acaaagtcat ggcttatcaa tttaaatt
//
LOCUS       DAZKNV010000040        24576 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000040 DAZKNV010000000
VERSION     DAZKNV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.040"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(154..552)
                     /locus_tag="ACG8M1_001830"
     CDS             complement(154..552)
                     /locus_tag="ACG8M1_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFQ0422515.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(549..1322)
                     /locus_tag="ACG8M1_001831"
     CDS             complement(549..1322)
                     /locus_tag="ACG8M1_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFQ0422516.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1319..2002)
                     /locus_tag="ACG8M1_001832"
     CDS             complement(1319..2002)
                     /locus_tag="ACG8M1_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFQ0422517.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2169..3056)
                     /locus_tag="ACG8M1_001833"
     CDS             complement(2169..3056)
                     /locus_tag="ACG8M1_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422518.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3053..3922)
                     /locus_tag="ACG8M1_001834"
     CDS             complement(3053..3922)
                     /locus_tag="ACG8M1_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422519.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4059..5345)
                     /locus_tag="ACG8M1_001835"
     CDS             complement(4059..5345)
                     /locus_tag="ACG8M1_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422520.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5618..6196
                     /locus_tag="ACG8M1_001836"
     CDS             5618..6196
                     /locus_tag="ACG8M1_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0422521.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6196..7125
                     /locus_tag="ACG8M1_001837"
     CDS             6196..7125
                     /locus_tag="ACG8M1_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422522.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7122..8858
                     /locus_tag="ACG8M1_001838"
     CDS             7122..8858
                     /locus_tag="ACG8M1_001838"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0422523.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8921..9757)
                     /gene="pheA"
                     /locus_tag="ACG8M1_001839"
     CDS             complement(8921..9757)
                     /gene="pheA"
                     /locus_tag="ACG8M1_001839"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFQ0422524.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9754..10263)
                     /locus_tag="ACG8M1_001840"
     CDS             complement(9754..10263)
                     /locus_tag="ACG8M1_001840"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFQ0422525.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10256..11551)
                     /gene="aroA"
                     /locus_tag="ACG8M1_001841"
     CDS             complement(10256..11551)
                     /gene="aroA"
                     /locus_tag="ACG8M1_001841"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFQ0422526.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11564..12655)
                     /locus_tag="ACG8M1_001842"
     CDS             complement(11564..12655)
                     /locus_tag="ACG8M1_001842"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFQ0422527.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12672..13838)
                     /gene="aroC"
                     /locus_tag="ACG8M1_001843"
     CDS             complement(12672..13838)
                     /gene="aroC"
                     /locus_tag="ACG8M1_001843"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFQ0422528.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13840..14904)
                     /gene="aroB"
                     /locus_tag="ACG8M1_001844"
     CDS             complement(13840..14904)
                     /gene="aroB"
                     /locus_tag="ACG8M1_001844"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFQ0422529.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14937..15959)
                     /gene="aroF"
                     /locus_tag="ACG8M1_001845"
     CDS             complement(14937..15959)
                     /gene="aroF"
                     /locus_tag="ACG8M1_001845"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFQ0422530.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16618..17592)
                     /locus_tag="ACG8M1_001846"
     CDS             complement(16618..17592)
                     /locus_tag="ACG8M1_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFQ0422531.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17573..19456)
                     /locus_tag="ACG8M1_001847"
     CDS             complement(17573..19456)
                     /locus_tag="ACG8M1_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFQ0422532.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19474..21699)
                     /locus_tag="ACG8M1_001848"
     CDS             complement(19474..21699)
                     /locus_tag="ACG8M1_001848"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFQ0422533.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21814..22848
                     /locus_tag="ACG8M1_001849"
     CDS             21814..22848
                     /locus_tag="ACG8M1_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0422534.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22915..23928)
                     /locus_tag="ACG8M1_001850"
     CDS             complement(22915..23928)
                     /locus_tag="ACG8M1_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0422535.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24006..24194)
                     /locus_tag="ACG8M1_001851"
     CDS             complement(24006..24194)
                     /locus_tag="ACG8M1_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFQ0422536.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7061 a         5341 c         4397 g         7777 t
ORIGIN      
        1 tagcatattt tgaaaagaaa gtctgatgct tagagtagaa tttcataaaa atttactatt
       61 tcataagtat tcacgagaaa aatacaaaca aaaaagcgga aataacgctc atccgccttc
      121 ttgtttgtgt ttatttcctc ttcaaacgct tgtctatgat tcagactttt ctctatcgtt
      181 attttcatct aaaagttctt gcattccgat aatttctcga tattgatgaa tcttagtgat
      241 accaatgact ttgtctacat caatactaaa acaaatacca ttacctggaa tatcgatgtt
      301 gatgccttga ccaatcgcat ccattacttt attcgtcaaa ctatcgggta ctaatgtcaa
      361 cacaatatct ttttctggcg aaatgtccaa acctaaaaat ttccctgaat catgtacacc
      421 agaacctctt ccatgtaaga tcgttccgcc tgctgcacct gcttcttttg aaaagtcgat
      481 aacatcttcg cccattcctc cgtcaacgat cgtcacaatc atgtgaagat tcaatgctac
      541 aagatctttc atttgctttc ccccaatttt tgcaatcttt ctttttcgat tctgtctttt
      601 tcatcttttc gtttataaat atatcctagt actaaagtgg ataatattgg tgtcaatgca
      661 atcattgcaa ccacaccaaa cccgtcaatg atcggatctc ttccttcaat ttgtgcagcg
      721 attgccacgc tcattgataa aataaatgtc gaacacatcg ggcccgttgc tactccaccg
      781 ttatcaaaag ccattgctaa aaagatcttg tccacttttc gtcctaaaat aaatgctagc
      841 ccgtatcctg ggatcaagaa ataataaaga gagaatccga cgagcaaacg ccacatagac
      901 aatcctactg ctgcgccgat cccaattgaa attaccatca gcatgatttt cgatcggatt
      961 ctcccctcgc tcaattcttc aacctgtttg atcattacat gaatcgccgg ctcagcaaac
     1021 cctactaaga accccattaa aaagccaagg ggaaccagta tataattgta aggcaatccc
     1081 gcaatagcac tgcctaaatg ctgtcctacc ggtacataag ccatattgac tccgtgcagg
     1141 aaaaggatca acccaatagt cgttatcaag aaacctttca taatgtcaaa gaaacgcttt
     1201 ttgcgcatac gaaaactaat gatattcatt aaaacaaata ggattacgat aggtgccact
     1261 gccaaaatga cttccatggt aacgatttcg attccatcta tcacttgctg ccagaaactc
     1321 attggaagat cacccccaaa atcatcacgg caagaatcgg ccctaacgaa gcaataccga
     1381 ccattccaaa actgtcattt tcatttttct tttgtttgat catactagtc atccctccgg
     1441 caagggccaa gataaatgga acagttactg gaccagtagt cactcccccc gaatcaaaag
     1501 caatcggcat aaattcggaa ctggtgaaaa atgaggcgat caaaacgcct atgtagccta
     1561 tagccatcaa ttgataatag gatagcttga atacgacccg aagcagcgca aaggctagaa
     1621 atactccagt gccgacgctg acgatcccaa tcagcaacac tctgccaatc tctccgtcag
     1681 atatatcata tacttgttgt cccaaaactt gcacggaagg ttcagcaatc gtgatcacga
     1741 tcccgatagc aaatcccaaa ctgaccaaaa cggtcaaact tttctttttg atcatatatt
     1801 tccctactag atctccgact tccatcatag aataatctgc tccaaacaaa aagagcgtca
     1861 ttccgatcat catgattgcc gcaccaacca gaaatgaagc gaggtcttct ccttctaacg
     1921 gtgcaaaaac aaacgttaaa atgacaatca ggacagtcat cggcaatata gcagcaatca
     1981 cttctttaaa attttttagc atgtatcctc ctcctttact ctttaagttt accttaaaat
     2041 gaaagagttt tcgagcacaa acttaaaacg ttatcattta atttttctca acataaaata
     2101 acacacgtcc caaaagtatc tttttacttg gaaaaatgac tttgaaggaa cgcgcttatt
     2161 gtgttttttt attttacaga gccgatcatt ccttgaacga attgcttttg caaaacaaaa
     2221 aatacgatgg cagttggtaa agtagcgatg actaatccag ccatgatcat tccatagtct
     2281 ggtgtatagg aagcacccat agcagataaa acaagcggaa ccgtccgttt atcaggagat
     2341 tgcaaagcta ctaagggcca taaataattg ttccagctac tcatgaatgt gatgattgca
     2401 gccgcggcat aggtattttt agccgtcggc atatacactc taaaaaaaat acttagttct
     2461 tttagaccgt ctaatcgagc ggcttctact agatcttttg gaaaagattt aacattttgt
     2521 cgaaagaaga agatcaaaaa agcagtgcta acagatggca ggatgacaac caagaaactg
     2581 ttgattccca aaaccgttcc gttcaattgt gaaaacattc gatataaagg gatcatcaat
     2641 gccgcaaaag gaaccatcat cgatagcagt agaatattga aaattaggtc ttttcgttta
     2701 ctttgataaa tctcaaatcc atatcctgcc attgacgaaa tcagcaatgc aaacacagtg
     2761 gtcaccaaag cgatcatcgc tgaattccaa agggaacgag taaaattcag ctcattggaa
     2821 aacaaatttt gaaaattgat gatcaagtta ctgccaatct ttatttttcc cgatgtgata
     2881 tccacgggtg tattcgtcat tcccaaaacc atccagacaa aagggaaaat ggaaataaat
     2941 gataggatgc ttaatgctgt atactttaat actgacccaa ttgtcgaacg aagttctaat
     3001 gcttgttttt tgacgttggg gcgttcgatt gtttcttttt ctaccatatt tttcatcgac
     3061 tttctcctcc tactttcgtt tggattatcg acaatatcac aataaaggaa acaataacaa
     3121 aggaaactgc tgccgcatat ccaaaattag gcgtgaattt ataactcaaa ttatagatgt
     3181 attgagatag ggtggtcgtt gcatttgctg gtcccccgcc agtaatattt tgtacttcat
     3241 caaaaagctg caatgtcccg atcgtcgaag taatggaagt aaacaaaatg attggtttta
     3301 aatttgggat cgtcactttg ataaactgct gccatttaga agcaccgtca atagatgctg
     3361 cttcataaat ctccgaatca atattttgca tgcctgaaag gaaaaaaatc atattgtatc
     3421 cagtccaacg ccaagtgatc gaaagaatga tcagaactct cgcccaaatt ggatgagtca
     3481 accagccaat cggtgtgtca atcataccaa tgcccaacaa caagttgttt acaaggccag
     3541 attgagaaaa tagacttttc atgatcagag aataactgac catcgaagtg atacatggaa
     3601 gaaagatagc ggttcgaaac aaccctttat atttcaactt tttatcattt aaaaggttgg
     3661 aaataaaaag tgctagaaac aacatgatcg gtacttgtac aagtaaatac aggaatgtat
     3721 taaaaaaagc ttttttaaaa gttgcatctg tcaacatccg ctgataatta cctaacccgt
     3781 taaatgtcat attgacaggg ggaccacttt gaaaagacgt gatcaaagcc aaaaccatcg
     3841 gaataaaaac catgattgat atcaaaatga ctggcaagat taaaaaagca tgcccgtttt
     3901 tgaataaatc tttctgcttc attcttttcc ctccaattct atcattgatt atctacatga
     3961 aaagacaaga aagacaatat ctgtaaggca gacgtgatct tttttgtctt ttcgtttgtc
     4021 tgatgaaaaa gcgaagaaat tcactttttt accaccgatc aattagccaa ttgtgcttct
     4081 acttgttttt gtgtatctgc tagtaccttg tctgtctctt ctccattgat gattcgatga
     4141 agagcttcag ctacgactgc ttcaattgca taggtctcat gtccgtaatt cacttctggt
     4201 atttcagatg tccatgttga aaaatcgtca aagatctttt gaccactgta aaattcagaa
     4261 gcttcttgat aagcttcttg ttcattcgcg ctaagcatcg tagatactag tccgatttct
     4321 ttcgcaagag tgcccatcag ttcttcattc gaagcaaacg ttgcttctag gaaatctttc
     4381 gctgaatctt ctccagctac tcctttgatc acataccagc cagcgccgcc aaggttagaa
     4441 gcttgcgctt tttgcagatt ttctggaagt gcaggtattg gtgcaatctt ccattttcca
     4501 gattggtttt ctgctccttg gatcgttgaa gaataccaag cgccagttgg gctagaagct
     4561 actgctcctg attgtatcgc agttactcca gcattccagt cagaggtttg ttcgactaga
     4621 tcttctttca aaagagtggc aaacaattca agaccatact ttaaagatgc attgtcttgg
     4681 atcgtgactg tctccccatc ttcagatgta taccattctc ctgcctgttg cataatcatc
     4741 cttactcgac caaggtcaga aggattgact tcagcgattt tctttcccgt cttttctttg
     4801 acatctcgcg ctacttgaat atactcgtcc cacttcagat tctccatatc ctcttctgta
     4861 taacctgctt ctgccatcag atccgtacga tagaagtttg ctgttacgcc cgaatcgaaa
     4921 ggaacaccgt atattttatc tcctactttg tttaccgcaa atttatacgg tgcaaaatga
     4981 tcttccttta caatagcaga caaattagcg aatgcatctg gataagaagt caaatagcct
     5041 tgtatcctat aatcttcaat caagacgata ttgggcaatc cttctgtatt cccgctcgct
     5101 aaagcggtgt tcagtttctg aacgatatca tcctgagaca tcgtaacaac ttctatctct
     5161 gtttcttcgt tctcataaac tttttttgct tcattcactg ctttgatatt gaatgtctca
     5221 tcccacgccc agacagtgac tttttcttct ttgtctgctg tactactagc acttccgcat
     5281 cctgttaaga aacctgatgc tgccgctaaa caaacgactc cagcaattaa ctttctgatg
     5341 ttcattttta tccgctcctt ttccatccat tagttgttta cgtttgctac attcatcata
     5401 ccaaaatttg aaaacggttt ctttattatt cagatacttc aaaaatttct cctaaaataa
     5461 taaaaaaata caaatcaact atgacaaaag gaataatctt agcatctaga ccaaagatcg
     5521 aaatggtgag gtttctttaa aataaaaata tccttgcatt ttctcctaga aataagtatt
     5581 tttaaattac aagactattc ttaaggcggg taaaaaaatg ccaatacgcg taattcttat
     5641 cgatgatgaa cagacgattt tagatggaat gaaacagttg atcaattggt ctgagcacgg
     5701 gtttcaatta atagggactt tttccagtcc gctgaaagcg cttgattttt ctttggtaca
     5761 tgcaatcgat atcgtggtca cagatgtaat gatgcctgaa ttaaatggaa tcgaattatc
     5821 gcggctatta aaacagcaac aacctgaaac acagatcctt atcctctcta gctatgatga
     5881 atttgatatg gttaaagatt cttttaaaga aggcgtcgct gattatcttt taaagcctcg
     5941 attgagtcct gatttttttc taaattcctt aactgccgtt tcacaaaaaa tcaaaaaaaa
     6001 gcccaacaaa agcccaatca ccaatcgtta tgagcagatc tgcgagaatc tttcacagca
     6061 gattgctgga caaactcgtc cattgcttga ccctcttctt tttgaacaca ccttgttttt
     6121 ctgttatata ccgaaaaacg gccattcagt tcaaaacaag gctctaaaca aaaacagtcg
     6181 atcacccatt cattgatgga tagcgacgat tcgtttacta tttatcctgt ttctaccttt
     6241 tcggaagaat ccggctatgt aatcaatact gattccaaag atacacttag gaagtttgtt
     6301 caaaagtttc gtcaagaagt ttttccaggt gatttttttg ttgtttctga ttcttttgca
     6361 atccaagata tcaatgaaat attccaagag atcagaaatt gcaccaaagg acaacgtttc
     6421 tatcataagg gaaagaacct tgcttatcag catgaacttc ttccgttatt aaccaaccac
     6481 gagcagcaag caagtagtta tttaacaaaa atcgttcata aagactacgc tttagctgtc
     6541 aaagaacttg agaatttctt cacgacgata ttggaacagc ctattgatcc agcttatttg
     6601 aaacatgagg caatcaatcg tttctatgca ttactcaacg ctttggctga cgagcatgtt
     6661 gggaatgaag aactttcttt gctcaagatc gcccttcctt ctttattagc cgatgctgag
     6721 tatttcgaag atttttctat tcttgtcaaa gaaacacttg agaaactcac ccacttttct
     6781 gcaaatgcaa aaaaagacaa tttcgatatc ttgactttga tctacgagtt cgtccaggaa
     6841 aattatgaga aagaaatcaa tttacaactt ttatccgaaa aatatcattt ttcatatagc
     6901 tatctctcag ccatctttac tgaaaaattt ggtatcaact tttcaaaata tctaaaaaaa
     6961 gtccgtatca gtaaagccaa gctctttttg acggaaacac ggcttacttt gacggaaatc
     7021 tgtgagaaag tcggctatac cgaactgggt tatttctcca gagtttttaa agaagagaca
     7081 ggaatgacac cttctcaata ccgtaaagga acttttgtaa aatgagaaaa aaaatcaaag
     7141 agcatgaact ctttgccaaa cttctgttca ttttgttcat cggtcttttt ctgcaagcca
     7201 tcgtcatttc tttgtttatt tatcatcgat caagggatgc ctatatccag ctgttcaatc
     7261 aatcgaatga tgtggtacta aaaaagattc aatctgaatt tgaaagtttg aatgatacaa
     7321 tcgagaatac attagccgct tttgattcta atccagctgt caaaagctat ttttccaatg
     7381 atccagccca acatatggaa cagcttcagc aactaagaac aatccaaaaa atgaatgact
     7441 ctctttcaaa aatccatcca atgatcgatt acgatgtatt gatctttgga gaaaatggaa
     7501 gaacttttgt cggaaacgac atgctcactg ccgtatctgc cgattctttt tttcaatctg
     7561 cgattgctca gagagtgaat gaacgtgctg ctgatacaca aatgcttttt gcacaccacg
     7621 gattgactct tcgcgataag aaagcaccca gcgtcttctt tgtcaaaaaa ctgaaaaata
     7681 cattgaatca cgtttacgga tatgctgttt tatcgatctc atccaagcaa ctagcgaatc
     7741 tttttcaatc tgtagtaaat cctgagatat cgaagatctc cttcatgaac gaagaacaga
     7801 cgatcatcgc atcaaatgaa gaaaatacaa ttgggagccg atcaatgatt ttcaaaaaac
     7861 taacagtagg tgaaacaacg atttcaaatg gacagcagtt gacccgtctt cctctgtacc
     7921 gccaggattg tacattactc agtcaagtcg atcttcattc tttatctaac caaatgggcg
     7981 tgatttttcc gattattttg tataatatcg tgacacttgc ttttgctggc tcattggtat
     8041 ttatgtattt ggatcgacac acaaaatcga tctaccgctt gattgattcg ctaaaacggc
     8101 tagaggaaga tggcttaaaa gctactgttc ctgtacaagg aagccatgaa gtccaattgc
     8161 tagggaatac gatcaatcaa ttgctaagta atgctcagca tcattatgaa cagacgatcc
     8221 aagacgaaaa gaagaaacgt tcgcttgaaa tccaaactat gcaagcacag atacagcccc
     8281 attttattta taatacgctg actagcttga aatttttgat ttggcagaaa aaaacagatg
     8341 aagcagttca aggaatcgac agtttcatta ctttactaag aagtacgatt gggaaaaaag
     8401 aagaagtgat tccagtcaag gaagaaatca aaagcgtaca aagttacatc gatcttttga
     8461 gtatgcgata tggcgaaaga atctcggcta aaataatgat tcctgatgaa ctgcagtcat
     8521 tatctatgcc gaatatgatc cttcaaccaa ttatcgaaaa cgcctatctt catgcttttc
     8581 acaataaaac gcaaggattc atcacggtgt acggcaaaac aaaaaatcag cttcttttat
     8641 tcgaagtgat tgataacggc gatggcttcg atactgaaaa taccaaacaa aaaaatgatc
     8701 atttttcagg aatcggcatc agccatgtag atgagcggat acgcctaatg tatggcgatg
     8761 catatggctt aacgatccaa tcagtgattg ggacaggaac gactgtaacg atttgtctac
     8821 cgcttcttcc taaaaatcaa tcagaatatc aaaaataaag aatagccaag cgctgatttt
     8881 tttattttaa gttaaataaa tcaatcagta ttcttgactt tcatctacgc gtctcttcta
     8941 ctgtcagcac tggataacag cccaatattt gactttctcc tccgagcatc ttgatttctt
     9001 ggagcgcatt ctctactaat gtcattggac ggtccaacaa caaatcgatc acgaaaaaat
     9061 attctcccaa gctagttttc aatggtcggg attcaatctt acttaagttg atttcccgcc
     9121 agccaaaagc tgccagcatt ttatgaagca tccctggccg attagcaggt agtgtcaaga
     9181 tgacactcat ttttactgga gctgactgct ggctggtcat ctttcggtca ccgacgatcc
     9241 aaaaacgtgt ctggttcaac tcattatctt ggatattctc agctaagatc tccaatccaa
     9301 catgctgtgc tgtttctaat gaagcaatcg ctgctgcgtc ttctttcgga tgttctgcta
     9361 catacattgc tgcagcagtt gttgattctg ttgctactaa aggaacatta ggataatgcg
     9421 tttctaaaaa ctgttgtgat tgtgctagtg cttgtggatg tgaaaggatt tttgtaatct
     9481 ttgttgctgg attgcctaaa agctgctgct tgataggaag aacgatttca cttttaactt
     9541 cgacttctgg atgtttggaa agaagatcga ttgtgtgatg aacagctcct tccaatgaat
     9601 tctctacagg aacgacagcc agatcgactt gtttgcgaaa caaagcgcgc aaacaaacag
     9661 ggatggaagc atacgcagtc aattgttctg taggaaatag ctgacaagcc gcctgataag
     9721 tgaatgaact ttctggccct agatagctga cgttcatatg cttttgatcc tttctataat
     9781 ggtatcgatg atcttttctg gtgtttgatt ggtcgtgttg attcgatgtg tcgcactttc
     9841 ttcataccaa gaaagtcgtt gtgccaataa tgcttttatt tcttctcttg tttttccaag
     9901 agctaaaggt cgaatagacg tttcatcttg ttggatacga tcaactagac agtccgcttc
     9961 tgcctctaag taaagaacaa tcggctgtgt ttttaaaaaa cgccgatttt ctgcactttg
    10021 gacaatccct ccaccagtcg cgataatttt gtcttcattt gacagctttc ttaaaatatc
    10081 tgactccact tttcgaaagc ttttttcacc gtaatagtga aaatattcgg caatcgacaa
    10141 ttggatatgt tcctcaatct ttgtatctaa atctacatac tctttttgta aacattgagc
    10201 taacccttta ccgattgttg tttttccagc gcccatgaaa ccaatcagca aaatgctagc
    10261 catgagcttc tcctcctgac acaagttctg ctaaatcgtc aaaaaatgcc ggataagaga
    10321 ttgaaacagc ttcagctcct tctagttcgc aaggtccatc agctatcaaa gcagctactt
    10381 gcagcatcat accgattcga tgatcgcctc tgctggacac ttttgcgcca tgcagaggtg
    10441 tcggcccatg gatgatcaga ccgtctgctg tcgcttttat ctttgctccc attttctgta
    10501 attcttctgc caccgcatca attctgttgg tttcttttac ttttaattct tctgcgtctt
    10561 tgatgatcgt gattccttct gcttgagtag ccactaaagc tagaatgggc aattcatcaa
    10621 tcagacgcgg aatgatttct ccaccaatcg ttgctttctt caaatgactc gtcttgacac
    10681 ttaaatcagc cgattggttc tgttcattgt gattcgtctg ggtaatcgct gcgcccatct
    10741 cctccaacac atctaagata ccagttcttg ttggattgac cccgacattt tttaacaaca
    10801 gttggctttc cggaacaaga agtcctgctg ctagaaagaa agcagctgat gaaatatcac
    10861 ctggaacagt tatctgttga ccagttaatt tttgcggtcc ggtcactatg atcgttttat
    10921 cttccactgt gatccttccg ccaaattgac gaatcatttc ttccgtatgg ttacgggaac
    10981 gttctttttc aacgattacg gatgtgcctt ctgcttgtaa tgccgcaaac agcaaagcag
    11041 atttgacttg cgcactggct acaggcatat tgtatcggat aggtgataaa gagcgggttc
    11101 ctgtcacagt gattggtaga tactggtcat tttcttctcc ttgcaagtca gcgcccatct
    11161 cgcgtaaagg ttccatcact cgccccattg gacgtttaga caacgaagca tccccgaaca
    11221 gagtagtcgt aaaaggctgt ccagccaaaa tacccatcaa taaacgtatg gtcgtaccgg
    11281 agtttcccat gtcaattgat tcggttggtt ggacaaatga gtggctaccg cgaccatgaa
    11341 tcttgatcac ctcttcctct tcttcgatct cgacacctaa ttgttggaag gcatgtaaag
    11401 tactcagaca atcttctgcg cgcaaaaaat tttgtatagt cgtcgttcct tcagcaattg
    11461 ctccaaacat gatgctgcga tgggaaattg atttatctgc tggtatccta acagtccctc
    11521 ttaatccatg tatttgttgt aataattgca tttatccagc ctcctatttg atccagcaat
    11581 gataactggt attagacata atgattcttt ttgcttgtaa caaatcctgt tggtttttaa
    11641 aactgatttg cagtattcct aaaatatctt ccctggtctc ttggatcttc aaattaatca
    11701 aagaaactcc cgcttttccg atcagtccag ttacttctgc aataacgcca ggttcatctg
    11761 gcacatcgat aaataaatca aaaaaggcag gaatcgcgcc ttgcttatgg acaggcaact
    11821 ggtctcgact ttcttttgcc cgattgaaaa aagaaaagat ttccgattgg ttctcagtca
    11881 tgatccattc tgctatttgt gtcatttctt gttgccaatc tgccaatcgt tccaataata
    11941 tctgcttatt gctcaacaaa atatctgtcc acatgacagg atctgaggaa gcgatcctag
    12001 tgatatctcg aaagcctcct gctgccagtt gtttggctcg cggatactct tgattgaatt
    12061 gttctgcctg attgactaag ccagctgcca gaatatgtgg aaaatgactt agcattcctg
    12121 ttatacggtc atgttctctt gctgtaagag ttacatattt tgctttggtt ccgcaaaata
    12181 gttcttgcag tttttcaaca tcttttttcg tcttttccaa aggtgtaaag atgtaatagg
    12241 cattttcaaa tagtttagca tctgctgcct gtatacctga tttatgagaa ccagccattg
    12301 gatgtccacc gacaaaccga agatttttct gctcagcgga tgtcacgact tgctgcttcg
    12361 tactgctgac atccgtaatg atgacgtgat cagacaagtt gattctttca aggacatcaa
    12421 gataagctaa ggttgtacgg acgggaacgg ctaataagat aacgtctgct tgttctgcac
    12481 ctgtttcaaa atcacttgca acgtaatcaa cgatctgctg ttctactgct tgctcacggg
    12541 tttttgactg actatcccaa ccaactacta tcagttctgg attggtctga cgaatacaaa
    12601 gtgccataga agcaccaatc agtccaagcc ccacgataaa aacatgttgt gccatcttat
    12661 ttgccccctt tttagtaatg tttcaagtag tcacggtact ccttcactgc agctttcaac
    12721 tcaacaagcg aatcacttgg gaattttgac aatagctctg tcgctaccac agtggctaca
    12781 acattttccg caacgacgct agctgcagga actgctgtac tatccgaacg ttctacactt
    12841 gctttgtaag gttcttttgt atcgatatca acactttgaa gtggcttgta caatgtagga
    12901 atgggtttca tgaccccgcg aatgacaagt ggttcgccat tggtcattcc gccttcgaag
    12961 ccgcctagat tattggtacg tcggaaatag cctctttctt cttcccatag gatctcatcc
    13021 atcacttctg agcctggtaa tgaaccagaa gtgaatccga ccccaaattc tacgccttta
    13081 aaggcattga tactaaccac agcttgtgcg attttggcat ctagcttcgt gtcccattgt
    13141 acgtagcttc ctaatccagc tggaacgcct ccaacgagca cttctacaat tcctccgatc
    13201 gtatctccat ttttctttgt ctgatcgatc aaatctttta ttctttgctc aactgctgga
    13261 tcaacaactc gtacttctga cgcttcagaa atttctttga tttcttgaat cgagatattt
    13321 ccaggtattt ctgcttggat tccaccaaga caaatcacgt gtcctgctac gatgatgtca
    13381 agttcttcca gaattttctt ggcaattgcg ccgattgcta cacgcatggt cgtctctctt
    13441 gcagaggacc gttcaagcac attccgaaga tctcgatgat ggtatttcat accgcctacc
    13501 aaatccgcgt gtcctggacg cggacgtgca actcgccgca gtgattggtc tttttcaggc
    13561 acttctgcta cagacatgac agttgtccaa tttttccaat ctttattttc taccactaaa
    13621 gtgacaggtg aaccaattgt tttgccgtga cggatgccag acgtgatccg aacacgatct
    13681 ttttcgatct tcatccttcc tcctctgccg taaccagctt gtctgcgagc gagttcgtga
    13741 ttgatttctt cttctgacag aggtaatcct gctggtagtc cttcaataat ggctgttaat
    13801 tctggtccat gggattctcc cgcagtcata taacgcatct tacagtcctc ctaagtaatc
    13861 tttgaatgtc tctgtgggaa caggaacgat ttttgcttgc ccaatctttt ctagcaagat
    13921 gatattcaat tggcttcctc ttgctttctt atcatgggtt atcgcgtgga ataattcatc
    13981 tggatgactt agatcgtacg taatcggcag atggaatttt tgaagtatcc tttctaaagc
    14041 agctgtcgat ccagttggag acaagccgat tttttctgca tgagaagtga tggctaccat
    14101 tccaatagct actccttctc catgactgac taccccatat cctgctgtat tttcaattgc
    14161 atggccaatt gtatgaccaa aatttaaaat aagtcgattt ccttggtcaa agacatcttc
    14221 ttccactact tttcgtttga tttccaacgt agcagtaatg attggaacag catgttccag
    14281 aagatctttt tcgtctttca gctcgttcag ctgtttccaa agcgttgcat ctgctatagc
    14341 tgctgatttg atgatttcag cgattccttc tcgtaaacga cgtaccggca aagtttttag
    14401 aacctcagga tcaatcaata caccagctgg ctggctaaat gttccgacaa ggtttttcgc
    14461 tttgtttgta ttgactgctg tcttcccgcc aatactagaa tctacttgtg caagtagcgt
    14521 agtcggaatt tgaacgaaat ggatcccacg catgaacgtc gaggccacga atgctgctag
    14581 atcacccacc attcctccac caagtgcaag tatcccatcg ctgcgggtaa aatcattatc
    14641 tgctaaaaaa tcgtataact cagctgcttg ttctaaagat ttactggtct cacccgccgg
    14701 tacgattgaa aggactggtt caaaattagc ttgtctcaat tggaacatga ttttttctgc
    14761 atatagtgga gcaacgtttg tatcagtgat cacagctact ttttgaggtc tccaaatcgt
    14821 ttgaagccat gatccagcct gttctagtgc gcctttttca atatgaatat cgtatttttg
    14881 gttatcaaca tgtacagtaa gcattcgttt cacttctttc ttttaaaaag ctggaattaa
    14941 tcgagtgtct gaatcttttc cattgcttct ttcatgatcg caacttcttt catcatgcgt
    15001 gagtaagtct tttcattcaa cgattgggga ccgtctgacc aagcatttgc aggatcagga
    15061 tggatctcta cgatcatgcc atctgctccg cttgccacac ccgcacgagc cattggtggt
    15121 acaagttccc aaattcctgt accatgactt ggatcaacaa tcacagggaa atgagttaat
    15181 tttttcatca atgggacagc acttaaatca aacgtattac gtgtcgctgt ttcgtaagtc
    15241 cgaatcccac gttcgataaa aatgacagga gatttgtctt cgactgcaat gtattctgca
    15301 gcattaagcc attcattgat cgtaccggaa attccacgtt tcaatccaac aggtttacct
    15361 gttttaccga cagcagatag cagtttaaaa ttttgcatat tacgtgcgcc aatctgtagg
    15421 atatcgctgt actcagccac catatcgata tgcccttcat ccatcacttc agtaatcact
    15481 ttcattccaa attcatcagc cgcttgacgg atgtatttca atccttcttc ttctaaacct
    15541 tggaaagcat atggagaagt acgtggtttg aaggcaccac ctcgcagaat ttttgcgccc
    15601 ccggctttgg ccattcgcgc acattctctg atttggtcta atccttcgat agaacaagga
    15661 ccagccatcg tcacgaaact gccgtcacca atttttactc cgtctacatc cacgactgta
    15721 ttgccaggat ggaattctcg agaagtcaat ttgtatgtgt ttaaaatacg cacagcattt
    15781 tctactcctt catagcgtgt aaatgctcct tcttgtaaac ttcgcgtatc accttttagt
    15841 ccaatcacta ctcgttctgt tccttgatcg attgagactt tgaatccttc tttttcgata
    15901 tgatcgacga ctttttttat ttgttcttcc gttgcttctt ttttcataat tactatcatt
    15961 gtttttcccg ctttcttttg tttacttatc tatcttggct gattttctct actttttcaa
    16021 ggtggtttta cattaattcc tactaaatga ccgtgtcctg ttgttctcat tttcgctcct
    16081 tctttcctac ttatgaccca gataatcaac aaaaaaagat gtccctgtag gaaattgcct
    16141 ctacagtgaa catcttcaac gagccttaaa aagcgctgca aaaatataaa atagccacta
    16201 tagatgaatt tctctacgtg gctgtaagtc gtgtttaaaa atctttagcc atcatagata
    16261 caaacctggt ttgtttgtac ccacgaagtc atgaatacaa acctatctaa aatagctaaa
    16321 gtaatacgta ttcagttttg taagttttct agatttcata aaaaatcgct ccaaactgat
    16381 gtaagaattg tacctagtat agacataaaa aaatcgactg tcaatcattt ttatgaaact
    16441 ttttttaatt ttctgatagt taactttgtt tttcagaaaa ataacaattg gttttattga
    16501 agaaaatagt catgaacaaa agtatctgag aactttttta ctctcttgtt catgacatat
    16561 agaataaagc agctttgtct tgtaaactcc gtttttcaaa taataatcta aagattgcta
    16621 ctgaataata aagccgattt catggtcctc ttcgctgctg attcggtaag gtgactcaac
    16681 atccgctccc cagctattga tacccccgac tcctcttact tttgcaaaaa tcgtaagaac
    16741 cgttcgtctt tctggcggta gttcttctat atgtgttgcc tgttccagtt cttctgcttt
    16801 gaatggtaaa gcggaaaaag caaatggcgt atcctgctgt tcaaatcgca acgaaaaatc
    16861 ttcttgatct ttatccgtat tatccaacgt ttgatttctt gttagttcta cccatttcgt
    16921 ttccatatgc atgccgcatt cttggggaac aaggtatggg gaaacgggga gtcctgccac
    16981 tttataaata ccttcgacac caccagccat ccgatccgga tatgtttccc ctgataggcc
    17041 ttcatactca aaaaattttg ctttcgttgg cataatgaac cttaaaccca atgcgggtaa
    17101 ttccggtaat cctttttgtc cataataatg catattgaca agcattttac cctctccagc
    17161 gatttggtag gaaattgtca cttgggtttt tggtactgtg ttgatttcca gtgtaaaaat
    17221 gatttcaacc gtttcagcgt attcattact tgaatattga ttatttactg gagcaatcgg
    17281 caaatcgatc tttttattgt ccaccagtac ttctatttct ttgacttttg gatacaatcc
    17341 ggctcctaac cacataccgg atttaaatcc aaatccgcta cctctgtcat tatcggtcgt
    17401 tgctcgccaa aaaactggaa gtgtttcccg gtatagccat tcttttccgt ttttattgag
    17461 cgattccagt ccgcctcttg tataagaaaa aatataatgc gtattccccg atttgacacc
    17521 taatgtacag tcgccgaaga cgattgcaac tttttccgta tccatatgac ttttatttac
    17581 tgtatttttc ataataatat cttacctcct gcatggcggg tttttcttgt ccatctgcaa
    17641 aaacgatccc attccctgag aattcatagt cacttggttt atcgtcaaag tcaccgccat
    17701 agcgcatcac ttctctgcct gtgattggat cagtcacttg gatcgcctga tctttaaaat
    17761 cccatatata gcctccttgg tacatttcat aacgatcaag caacgtcatg taagaatcca
    17821 ttccacctaa cgaattcccc atgtcatgca tatattcaca taagatgaac ggtttttccg
    17881 ctttattttc aaggtagtca atgatctctt ctggtggcgc atacatgcag ctttttacat
    17941 ctgaaatcga atcttcgaat gctggatttg gaaaattccc ttcataatgg acaagtcgat
    18001 cggggtctac ttttttgaag taatcgttca tttgtcgaat gttttcttcc gcataagatt
    18061 catttccaag agaccaaaaa agaatacttg gatggttttt taatgtttcg aaattcgttt
    18121 ttgctcgatc aagaacagcc gcctgccact gaggtactgc acctggtacg ttgtaagaag
    18181 gctcaaatgc gcccattttt tgccatgagc catgggattc gaggttcgtt tccgccatca
    18241 catggattcc tgcttggtcg cataaataat accaagtgat ctggttgggg taatgagatg
    18301 tccgtacgcc gttgatcttt gcatttttta tgatagccaa atctttttcc atatcttcta
    18361 tagtgatggc gcgtcctttt ttcggatgcc actcatgtcg atttaccccg ttgataatca
    18421 tccgttttcc attgaagtag atgattttat ctttgatttc gattttacga aaaccgaagg
    18481 aatagtcaat atactccgtt actctttttt cttcgtctat cgtctccaat tcaagcttat
    18541 ataaattggg ctgaaaatgc ccccacagtg ccacattttc aaatccatcg atgcgaatcg
    18601 tcatttgctc ttttaacgga tattgctgtt gatagatttc cttcccatca ggatctagta
    18661 tcgctacatt cagctgactg tttttggcta cttgctcaaa agacaaatct acttcaagtt
    18721 tgccattttg acatttgtca tctaagcgag gtttgatcca aagatcttct aaatggtttt
    18781 gtcctcgagc aactaagaag acatctctga agatcccaaa aaatcggaaa aagtcctgat
    18841 cttccaagaa tgcagctgta cttcttttgt aaacctccac agctagaata ttttcttctt
    18901 ccaaataagg tgttaaatca aattcagacg gagtgaacga atcttcggca tacccgataa
    18961 aatgaccatt caaccaaata aacattgctt gttctacacc agcaaaatga atcgagattt
    19021 gttttccctt tagaccttct tctaatcgaa aagtcgtcaa atacgaacca accggattgt
    19081 ctttagcagc tgaaaagatc ccttccgcct ctttctcagg gcttgtcgtg aaagggggac
    19141 ggcgaaatac atgtccctcc cacggataca tcgtattgat gtaatggatc ttgtcataat
    19201 ttgctaattc aatatgacta ggaacagtga tttcatcaaa agaacaggca tcaaaatctt
    19261 ttttataaaa tgtttttggt cgtaccgaag gatttggcga ataacaaaaa cgccatgatc
    19321 catttaaaga ctgtttaagg gaggatgtgg tttctacttc ttcccttgtt gcataacaaa
    19381 catgatcgct atgtgcattt gattggttca ctctaaaaac ttgtggatca tctaaccatt
    19441 ttatatttgc tttcatactt ttttccttct ctctcataac tttttgaaat gaagcagttc
    19501 tgtttggaaa tcaccttgaa aatcggggaa gtaaagtcca actgtcatca attcggcccc
    19561 cgaaaatatc cgcttcgagg tctgttcctg ataaagtgcc tcatcatcta accccatcag
    19621 atatacttca tggaacgctg gttgagctga agctagtatc ctccctaaaa acacaatagc
    19681 ttcatcttgt ttaggagaca caaacatcca tgcggcaata ttttcttcaa aaggactcgc
    19741 caaacgataa taatggccat actggatcac cggacgaatc gtttgatagg atataatttg
    19801 gtcttttact tgcttttttt cttcaggaga cagctttgtc aaatccagtt cataaccaaa
    19861 aacagcgctc atagctgttt ctcctcttgt tttcaacgaa gtagatctgt cggtctgatg
    19921 atttggtaca gctgatacat gagctgtgat ggacgaaatc ggataagcaa ggcttgttcc
    19981 atattggatt ttcatacgct ccactgcatc cgtgttatca cttgtccatg actgcggcat
    20041 ataataaata aacccggcat caaaccgtcc acctccacca gaacagcctt cccataagat
    20101 ttccggataa tcagttgtca aatgttcaag tagttcataa agcccgagca tataacgatg
    20161 cgctacttct ccttgtctct gtgggtcaag ggtaatcgaa tagacatctg aaagcgaacg
    20221 gttcatatcc catttgatgt agtcaagagg aatcgtatct aaaatctttc tcatttgttt
    20281 ctcaatcgtc tgccgaacat ctaaccttgt aaaatccagt acatgttgtg atctggaagc
    20341 agaaggcatt ctacctggct cctgcataag aaaatcagga tgtgttcgat acagttcaga
    20401 atcaaccgag atcatttcag gttcaaacca taaaccaaat ttcaatcctt tgctatgagc
    20461 ataatctgct atttcacgta atccatttgt caacttgcct tcatactcga accagtctcc
    20521 taatgaagaa ttgtccgcat ctctttttcc aaaccagcca tcatctaata cgaacatttc
    20581 gatgcctagc tcctttgctt catcaatgat cgccttgatt ttttcactat tgaagtcaaa
    20641 gtaagtggct tcccagttat tgaccagaat cggccgttca gcaaattgat gacgacctct
    20701 tgcgattctt tcacgtagca actcatggtg gatctgactc attttgttca atccctgact
    20761 tgagtaagaa aggatcattt caggtgtttg aaaagactgg cctgcattca attcccacga
    20821 aaaacgatgg ctgttgatcc caccgacgac tctcaattga ttgatctgat ctttttcaag
    20881 ttcgaaagaa tggttgccgg aataaacaaa ttgaagtccg atcgcttctc cagtattttc
    20941 tgtcgtatga tgatgaacta aagcaataaa gttattcata tggtgactgc tcgttcctcg
    21001 acggctttca aatacttttg ttccagataa aacagattgc cgtgaaatct gtctttcatt
    21061 gacatgtgct cctggcaaag caatgacttc atcaaatcgc ctagtatggg caaagtctag
    21121 ctggaaacta gccgcttttt ctagtttgat tgtttctccg gtttcatttc ttatctttac
    21181 agatcgtgtg atcactgctc tatcagtaaa tatggtatag aacaaatcga aataaatcgc
    21241 tgtttctcta tccttaagtg aaatcaccaa cgtttgtgcc tctgacttgt ccatcacata
    21301 agtttgaggc aagccttcga tctctggctt cccatctgta atataatggc tgtcatatct
    21361 cagatccagt aagtctgatc cattcttgcg ctgaatgatc gatgcgggcg ttcgaaagtc
    21421 catgctgcca tgagaagagt attcttgcgg tagtgtatct ttcgacagag accggtcagg
    21481 atttaaggga acatttcctg aaaatccacg atctcttcgg ggataatttt tattgtcttt
    21541 gtactgcttg actggtttgc caaaataaat atgcgccaat acattgcttt cttctatctt
    21601 tatcagataa gaaagaaatg tatttcgtaa atggaagact cggctctttt catcaaataa
    21661 gatgaaattt ttatctgttt ttctatgcgt aatatccatc atttcactcc caacaaaacg
    21721 gaaaccgttt actttttttt ataattcctg tatactgttt actaaacaat tttgtcaata
    21781 aaaatttttt atttttttga ggagtgtgta aaaatggttg gaattagaga tgtcgcacga
    21841 aaggcaaatg tctctcctgc tacagtttcc cgtgtgttga ataacgatca gacgatccat
    21901 gtggctcaga ctactcggca acggatagta gaggcagctg ctgcgttgga ttatgacatc
    21961 agtactcgta aatatatcaa aaagagaatg ccttcgattg gtgtgatctc tacgatcggc
    22021 aaagcgagcg aagaacagga tatctattac aaacatttgc gagtagggat ggaagaagaa
    22081 gctcgacgtc tgcatttagg gatgaatcga atctataatc tatctgataa tcctaaacaa
    22141 tgggaagatc tagatcagtt aggtgcggtg atcgttgttg ggactgttac gaaagaatcg
    22201 attaccgcct tgttaaaaca aaacatgcaa atagtcgtcg tggataaccc tgacatccag
    22261 caagaggtcg atatggtgta tgcagatctt gaacggatga ctaaaaccgt actggaattg
    22321 ttcttagaaa atggtcataa aagaatagcc tatatcgggg gatataaagt cgatatggat
    22381 gaattcggtg ggaagcagat ttctataaat gaaaagagga tgcgtgccta tcagcatttt
    22441 atgatcgatc atcacttaga aaaatatatg tcttatcatc taggtggctg gacagaaaaa
    22501 caaggtgagg tacttgcgac taatctatta gaaaatgaat cccctcttcc tactgccatt
    22561 cttgtcggga gcgatccaat ggcaattggt gtctatcggg cattgaaaca aaaaaatatc
    22621 caaattggag aagagattgt tgtagcaagc tttgataata tcgagacaat cgcaaacctc
    22681 tcccctggct tgaccagtgt tcaaatcaat gcgaaatcaa ttgggcaagc agctgttcga
    22741 atggcattgg agcgaattga cggtatacgg gacgaaccaa tcattttgac ttatcctgca
    22801 cgattgattg ttagggaaag ttttatccca agaacaaaaa ggtattgaaa gagaggttgt
    22861 gaaaagccgc ttcgtttctt catactcaaa acgaaacggc tttttcacaa cctcttactt
    22921 atacttattc acaaaatcca atgtctgctg gtaacaattt tgcgattctt ttagcgtgta
    22981 atcaaattgg tattcatggg taatctcttt ttttgtatct gtataaaaca aggattgcac
    23041 gggtaccttt aattctgtca accgattttc taatgcttga ccttgctcct ggaatgagta
    23101 tgcatttccg tcagttatat acgttggcgg aaattcctta gaaacatggt cagccacact
    23161 agcttctttc aattgctcac tcgttttcca atcttttgtt ccaatcaacg accacgcaac
    23221 ggttttgacg aaaaacttca taaatcgatc atccgaatgc tgctgtgctg ttagcttcaa
    23281 atcaacaggt ccgcaataag aaatggttcc tttcagacta tcttttggaa gtagctgttt
    23341 gattttcatt tgtttagcat acgcatcatt cgtttgtata gctgcatatt gcaatgcgat
    23401 ttgtgaacct gcactatctc caccaaaaaa taattgttcc atgtctagca atttgtcgtc
    23461 tttttcttca gctaataaat ctttgatcag ttcattcact tgaagaactt gattagggta
    23521 ttctgaatca ggcgctaatt cataattcat cgcaaccact gcgatgttgg cgtctgaaac
    23581 taattttgtc gcaaattctt tgacacccga tttatctccg ccgacgaatc ctccaccatg
    23641 tacccaaaat agaacaggaa caggcccctt gctgtttttt ggatagtaga tgtcataagt
    23701 attctcttta tacttggact catacgtcaa atctgttttt ttcgccacgt ttttttctgc
    23761 ttgatcgaac gtttttttat cagtgatttg aacagtattt gaaaacatat ggttgatcaa
    23821 gaatgctcca ggtctggggg aaagctggaa ggcaagaaag attgcaaacg cgatcccaag
    23881 aatgattccg aagaaccatc cgataaattt aagaattttc tttttcataa ggctccctca
    23941 gtagttagta ttaagcattc tgattatacc atagtgttat ttcctatcaa gctctcctag
    24001 atgatttaat gattttcccc aaacttcttc tgcaatgctt ttgacaaaag aaattttttc
    24061 cattgttctt caaacaaaac attttcttct tctgttgaag caaatccaca ttgaggactt
    24121 aagcacaaac gatccaaagg cagatatcgt gtcgcttcgt agatccggtc aatcacttgc
    24181 tggtgctctt ccatttcgcc atttttcgtt acagtcaaaa tctaagacaa ctaatttatc
    24241 ttcagagact ttctctaaaa gaacaaaact cccagcacgt tcactatcgt attctaaata
    24301 ataggcacgg acattttctt gagtaaaata atgggtctgc tacgtcgtca tcccccctga
    24361 tgccgccaaa atcgaataat aatttccgcg tcaaacatgt atatttagtg ttgaatcatt
    24421 tgagaatatg aaaataaaaa tctttttgat caatcagtta atcaaattga aataacgaaa
    24481 aatctgagac agaatgacgt tcattctgac ccagatttga ttttgcacaa ctcaacagtc
    24541 cttattggca aatcgccaaa ataatgtaga ctaact
//
LOCUS       DAZKNV010000041        23697 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000041 DAZKNV010000000
VERSION     DAZKNV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.041"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..145)
                     /locus_tag="ACG8M1_001852"
     CDS             complement(26..145)
                     /locus_tag="ACG8M1_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFQ0422537.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            324..1985
                     /locus_tag="ACG8M1_001853"
     CDS             324..1985
                     /locus_tag="ACG8M1_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0422538.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2055..2402)
                     /locus_tag="ACG8M1_001854"
     CDS             complement(2055..2402)
                     /locus_tag="ACG8M1_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFQ0422539.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2486..3427
                     /gene="opp3b"
                     /locus_tag="ACG8M1_001855"
     CDS             2486..3427
                     /gene="opp3b"
                     /locus_tag="ACG8M1_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFQ0422540.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3428..4471
                     /locus_tag="ACG8M1_001856"
     CDS             3428..4471
                     /locus_tag="ACG8M1_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422541.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4477..5547
                     /locus_tag="ACG8M1_001857"
     CDS             4477..5547
                     /locus_tag="ACG8M1_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422542.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5537..6490
                     /locus_tag="ACG8M1_001858"
     CDS             5537..6490
                     /locus_tag="ACG8M1_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422543.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6502..7512
                     /locus_tag="ACG8M1_001859"
     CDS             6502..7512
                     /locus_tag="ACG8M1_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFQ0422544.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7797..8618)
                     /locus_tag="ACG8M1_001860"
     CDS             complement(7797..8618)
                     /locus_tag="ACG8M1_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFQ0422545.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8715..8993)
                     /locus_tag="ACG8M1_001861"
     CDS             complement(8715..8993)
                     /locus_tag="ACG8M1_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422546.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9261..11270
                     /gene="metG"
                     /locus_tag="ACG8M1_001862"
     CDS             9261..11270
                     /gene="metG"
                     /locus_tag="ACG8M1_001862"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFQ0422547.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11749..12336)
                     /locus_tag="ACG8M1_001863"
     CDS             complement(11749..12336)
                     /locus_tag="ACG8M1_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422548.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12511..13833
                     /locus_tag="ACG8M1_001864"
     CDS             12511..13833
                     /locus_tag="ACG8M1_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0422549.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13988..14764
                     /locus_tag="ACG8M1_001865"
     CDS             13988..14764
                     /locus_tag="ACG8M1_001865"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFQ0422550.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14757..15326
                     /gene="rnmV"
                     /locus_tag="ACG8M1_001866"
     CDS             14757..15326
                     /gene="rnmV"
                     /locus_tag="ACG8M1_001866"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFQ0422551.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15319..16203
                     /gene="rsmA"
                     /locus_tag="ACG8M1_001867"
     CDS             15319..16203
                     /gene="rsmA"
                     /locus_tag="ACG8M1_001867"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFQ0422552.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16654..17283
                     /locus_tag="ACG8M1_001868"
     CDS             16654..17283
                     /locus_tag="ACG8M1_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422553.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17407..18516)
                     /locus_tag="ACG8M1_001869"
     CDS             complement(17407..18516)
                     /locus_tag="ACG8M1_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422554.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18725..19147
                     /gene="mgsA"
                     /locus_tag="ACG8M1_001870"
     CDS             18725..19147
                     /gene="mgsA"
                     /locus_tag="ACG8M1_001870"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFQ0422555.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19334..19432
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19470..20006
                     /locus_tag="ACG8M1_001871"
     CDS             19470..20006
                     /locus_tag="ACG8M1_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFQ0422556.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20046..21809)
                     /locus_tag="ACG8M1_001872"
     CDS             complement(20046..21809)
                     /locus_tag="ACG8M1_001872"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422557.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21812..23527)
                     /locus_tag="ACG8M1_001873"
     CDS             complement(21812..23527)
                     /locus_tag="ACG8M1_001873"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422558.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7644 a         4327 c         4806 g         6920 t
ORIGIN      
        1 aaactggctt ttgaacaccg tttattcaga taagggactg tgacaagact tttgtcacag
       61 tttctttttg tttattcttt tttatctttg tatggcaata atagacaata taacgaaaat
      121 tatttaatgg cttttggaag accatggaaa accttgtaca aagctatttt ttctgaaaaa
      181 ttccttgaaa cctcacgaaa aaatcattat tttatgaaaa agacaaaaaa aagtgttgat
      241 tttttaataa ttattcatta aactcttaaa caacttcaga aaatattaat tattctgaaa
      301 attccaataa aggggtacgt aaaatgaaaa agaaatttac atttggtttg gttgcggtat
      361 gcggccttgt acttgctgga tgttatggcg gcagttcagc cacaagcagt agttcagcaa
      421 aaagcggttc agcagatgga ggaggcgtat ttaacttagt cgtgcctcaa gaaatgccta
      481 cagctgactt atcagttgca acagatacaa tcagttttac agcattgaat aacgtttatg
      541 aaggaattta ccgtcttgat gaagacagca aaccacagcc ggcaggagct agcgagttgg
      601 cagaagtcag tgaagacgga ttaacttaca aaatcaaatt acgagaagac gcaaaatggt
      661 caaatggtga tcctgttaca gcagcggatt acgtttatgg ctggcaacga acagtagacc
      721 cagctacagc ttctgaatat gcttacctgt atgcgccagt tgaaaatgca gaagacatta
      781 cagctggaaa gaaagataaa tcagaactag ggatcaaagc agttggtgac tatgaattag
      841 aaatcaaatt gacgaaacaa acaccatatt tccaatatct gcttgctttc ccatcatttt
      901 tcccacaaaa acaatccgta gtggaagaaa atggggatgc ctatgcatct gcaagtgata
      961 aagctgttta taatggacca ttcacattag aagattttga tggaccagga acagatacag
     1021 aatggactta taagaaaaat gatcattact gggacaaaga tacagtaaaa ctttctgaaa
     1081 tcaaagtcag tgtagtaaaa gaatcttcta ctgcattgaa cttattcaaa gatggccaag
     1141 cagatgacgt gatcttgtct ggtgagttag cacagcaaaa cgcaaacgat ccagcttata
     1201 cttctgttaa agaagcgcgg acaagctata tcgaattcaa tcaacgtgaa aagaattcac
     1261 cattcaacaa tgtgaaccta agaaaagcta tttcttattc tatcgatcgt gaagctttag
     1321 taaaacaagt actaggtgac ggatcagttg tctctacagg attgatccca tcagatatgg
     1381 taaaaagtcc aacaacgaac gaagactttg caaaagaagc tggaaaatta gtttcttatg
     1441 acaaagataa agcaaaagaa tattgggaaa aagcgaaaaa agaattgggc gttgattctt
     1501 tagaatttga tttgatggct tctgatgatg attcatcgaa aaaagtaatc gaatatgttc
     1561 aaaactcaat ccaagaaaac ttggatggcg taacagtcaa accaacacct gttccattct
     1621 ctgtacgtct tgaccgctca acttcgggtg attttgacgc agtactaggc ggatgggctg
     1681 ctgactatgc agacccaagc agctttactg atttgtttgt cacaggtaat tcatacaacc
     1741 gtggtcgctg gagcaatgca gaatatgacg aagcagttaa agcagcttca tcaacagacg
     1801 ctggcgatga acaagcccgt tgggatgatt tccaaaaagc aatcaagatc atctctgatg
     1861 atatgggtgt cgttccggtg taccaaaaag cagaaggtca cctagtgaat gaaaaaatca
     1921 aaggtatcgt tcaccatgcg gcaggcgctt catgggatta caaatggaca tacgttgaag
     1981 aataatcgtt aataccgtga gcatgagaaa aaacgaggct gcggcaaatg tcgcaacctc
     2041 gttctcatat tcacttatcc taacaaagaa aaaagcatga aaatagcaga aagagcaatt
     2101 agtattccgg caatgatcag ccaaaagctg tacataccgt agctggcaga cgagagcgag
     2161 gaaaattctg gttttttctt tcggttcctt gttcgtgcaa gatggaccga tcgctgaaaa
     2221 tgatcgaaga aacccgaaga aaagacccat aaaaaaccgc cgataatcag aaacggcaat
     2281 gaccataaga atagatcatt agataattga atgagtgtaa aggaatggtt gatgagattt
     2341 tttattaaaa taaccagaat cagtagaaaa gctactgcgt aggggataga tttttttttc
     2401 atttgattgc tcctttattt ttggttcatt atctaataat gtagcgaaac atctgtcaga
     2461 agtcaaaagc tagggggaaa cattagtgaa tagttatatc aaatatgtat taaaacgtgt
     2521 ctttttcatg atcatcacgc tttggttaat tgcaacaatc acctttttct tgatgcaatt
     2581 gctgccgggc acgccatata cgaatcagga acgtttgagt cctgaaacaa tcgagatgct
     2641 aaataaacaa gtcggtttgg ataaaccagt tatcgtacaa tatgggattt atctttctaa
     2701 tttgcttcaa ggagattttg gaatttcctt ccaatttaaa aaccagccag tcgcacattt
     2761 gttagctgga agaatcggac catccttgca gttagggtta caggcaatta tctttggaac
     2821 agtcctaggg acgattttag gaacgatctc tgccatgaag caaaatacat gggcagatac
     2881 atcttctaca ctcgtagcga tattaggtcg ttccattcca aactttgtat ttgctgtttt
     2941 attacaatat atctttgcaa tcaaattaca agttttgcca atcgcaaaat gggatggctt
     3001 tgtgtacaca atcttaccaa caattgcgtt ggccatgtcg ccgcttgctg actctgctcg
     3061 gtttatccgt acggaaatgg tggaagtact gcatagtgat tatgtggaat tagcaaaagc
     3121 aaaaggattg agccgttggg aaatcgcctt taaacatggt cttcgaaata gtttgattcc
     3181 attgatgact ttattaggac cgttagctgt agcattgatg accggatcac tggtggtaga
     3241 aaatatcttt gctattcctg gtatcgggga acaattcgtt aagtcaatca caacaaatga
     3301 ttatcctacg atcatggctg taacgatcct ttactcattt atgctgattt ttgttatttt
     3361 gatcgtggat ctattgtacg gtctagttga tccaagaatt cgtgtttcag aagggagccg
     3421 aggataaatg gaaatgatac caaagcgtta tgaaacagtt gcagatatcc ctgcggatga
     3481 atttcttcca ttacaaaaaa ataccgaaga agaacgtgaa cagattactg caccttcttt
     3541 gaattttatc caagattcat ggcgccgttt aaagaaaaac aaagctgccg ttatttcaat
     3601 ggttttacta ttggtcatca ttttgatctc tgtgatcaca atctttgttt ctcctcatga
     3661 tccaactgcc caaaacgtgg cttatatcaa tttgcctcct cgtattccgg gaatcaatat
     3721 cgatggattg aatggaaaag caatggttgg tggtgaactt gttgataaat atgctcaagc
     3781 aaacgtccct tcaaacgtaa atttcttttt aggaacagac ggtttgggac gtgatgtatt
     3841 aagccgctta tttatgggaa tgagaatctc gttgctgatc gcatttattg ctgcattact
     3901 agatgtaacg attggtgtag cttacgggtt ggtttctggt ttgttaggcg gacgtgtcga
     3961 taacgtgatg caacgttttt tggaaatctt atcaggaatt ccaaacctcg ttgtcatgat
     4021 tttgatgttg gtcgtttttg aaccaggaat tttttcaatc gtggctgcta tggccatcac
     4081 aaactggata ccaatggcac gtatcgttcg tgcacaaaca atgaaattaa aagatcaaga
     4141 atatgtttta gctggattga cattaggtga atcaagaatg aaaattgcat tcaaacatat
     4201 tttgccgaat atctctagtg tcattattat tcaaatgatg tttagtattc catctgctat
     4261 tttcttcgaa gcctttttaa gctttatcgg tttaggtctt acgcctccgt cagcttcatt
     4321 aggaacgatg ttgagcgaag ggtacaagac attcctgtat ctgccttatc tattatggat
     4381 tccggcagta actttatcgg ttatcatgat tggctttaac ttacttgctg atggattgcg
     4441 tgatgccttt gatcctaaaa tgaaagagtg aagacgatga cgaaaatttt agaagtgaaa
     4501 gacttagaaa tctcttttga tacgtatgct ggaaaggtac gagcgattcg cggtgtcaat
     4561 tttcatttga ataaaggaga aacattggcg atcgttgggg aatctggaag tggaaaatca
     4621 gtgacgacca gaagcatcat gcgcttgctg tcaagcaacg ccaatataga tgctggtcaa
     4681 atcctcttta aaggtaacga tatcgttgga aaatcagaaa gagagatgca aaaaatccgt
     4741 ggtaaagaaa tagcgatgat tttccaagat ccaatgacct ctttagatcc gacgatgccc
     4801 attgggaagc aagtcgctga gtcccttaga aagcataata aagtttcaaa aaaagaggga
     4861 caaaaagctg cattagaatt gcttaaatta gttggaatac ccgaagctga gaaacgtatc
     4921 aacagttatc cgcatcagtt ctcaggaggt cagcgtcaac ggatcgtgat cgcgattgca
     4981 ctggtatgtt atccggaaat cctgattgct gatgaaccta caacagcgct tgatgtgact
     5041 attcaagcac agattttgga gctgctgaaa gaaattcaga caaaaatcga tacatcaatt
     5101 atctttatca ctcatgacct tggtgtagta gcgaatgtcg ctgatcgtgt cgctgtcatg
     5161 tatggaggaa gaatcgttga agttggaaca tcggaagaaa ttttctacaa cccgcaacat
     5221 ccctatactt ggggactgct tggttcaatg ccgacattag atagtgcgaa cgatcgattg
     5281 tatgctattc ctggttctcc accggattta ttgaacccgc caaaaggaga cgcattctat
     5341 ccaagaaatg aattcgcgat gaaaatcgat gcagaacaag aaccaccatt ttttgaacta
     5401 tcaaaaacac acaaggcagc aacttggcta cttgctccgc aggcacccaa agtgacaccg
     5461 ccagaagaaa tccaacgtcg ctgggctatc tttaaagaga aacaaaaaca tacttacggt
     5521 caaggaggaa ttgctgatgc caaataaact acttgaagtt aaaggattga aacagtattt
     5581 caatgtagga aaaaagaatg aagtacatgc tgtaaatgac atcagctttc acatttatga
     5641 aggagaaaca ttcggtttag ttggagaatc tggaagcgga aaatccacta ctggccgtac
     5701 gatcattcgc ttgaatgaac ctactgatgg tgagatatta ttcgacggtc aagatataac
     5761 gaagatcaaa gataaaaaag gtttgacgaa attccggcat gatgttcaga tgatctttca
     5821 agatccatac gcttcgttga atcctcgtat gaaagtcaga gatatcattg ccgaaggaat
     5881 tgatgttaat ggactagcta aatcatctga agagcgtgca aaaaaagtcg atgatctatt
     5941 gagaactgtt ggattgaatc caagccacgg tactcgttat cctcatgaat tttcaggtgg
     6001 gcaacgccag cgtattggta ttgcacgagc attggcagta aaaccgcgtt ttatcatttg
     6061 tgatgaacca atttctgcac tagatgtgtc gatccaagcc caagtggtca atttgttgca
     6121 agatctccaa aaagaacatc aattgaccta tctatttatt gcacatgatt tgtcgatggt
     6181 taaacatatt agtgaccgaa tcggtgtaat gcataacggc ttgttattag agatgggaac
     6241 aagtgatgaa atctataatc acggtgttca tccttataca gaaagtttgt tatctgctat
     6301 tcctctacca gatccagacc atgagagaaa acgcagaaga atcaaatatc aacctgaacc
     6361 agatgacgga caagtacgtc aacttcgtga aatcgcacca gaacattttg tctatgcaac
     6421 tgagcaggaa gtcccatatt acgcaaaaaa actaaaacga caaaaggaat ctcttctggt
     6481 tgctaactag gagggacata gatgctaaaa gcttttaaat tccgtatgta tccgacagaa
     6541 gaacaaaaac agcaattgat tcgtactttt ggatgtgctc gatttaccta taaccatttg
     6601 ctgaaaaagc ggcagaaaag ttggcaacaa acaggagtag ccaatttttc gctcacaccc
     6661 gctacattaa aaaaagaata cccattctta aaagaagtag acagtcttgc tttagcaaat
     6721 gcacagctta atttggatcg ggcttttcgc aattatttca agggacgtgc cagcttccca
     6781 aagcttaaaa cgaaaaaaag tatgtggcaa tcttatacga ccaacaacca aacccgtacg
     6841 atctatctgg aaaatggcta cttaaagtta ccaaaacaaa aagaactaat caagataaat
     6901 cagcatcggc cagttgaagg atcgattcgc tccgctacga tttctgctcg atataatgaa
     6961 gaattttatg tcgcactact ttgtgatgtt tcgccagtaa aaaaagaatc tttagctaaa
     7021 tggatcggga tcgcctatca tccgaagaca ttgatccaaa catctcgacc tctagaagta
     7081 actttaccaa aatttcacca gacagaagaa aagctgcaac atgcacagcg gaaattgaat
     7141 gtgaaagtcc gctccgctca ccatagaaag atcaggttag atcaggcaag caattatcag
     7201 aaacaaaaga gaaaagtaat ggatctttat ctgaaacaaa agaaccagcg agaagattat
     7261 cttgaacaat tatctgggaa attggtcaaa caatatgact acttatttgt agaatctttt
     7321 ccaaaagaag aggcacatgc tgatttttct attcacgact ggcataaatt aataacaaaa
     7381 ttgcgttata agtcccaatg gtataataaa aaatttcttt tgatcaatac cgacggagca
     7441 gaagaaagca attccgtaag aaagagccaa gtagtagaaa aaatgggcag acattcggtt
     7501 atcaagggat aaaaaatgaa tgaaactgat aggagcgtta gggttagcct tgttaataaa
     7561 aagtcttaat gacttttgtt tctaggaatt tttcttttga agaaaagctc actaattatg
     7621 acaaaccaat aaaacaatag cagaaaaagt tcgtacgagc tttttctgct attgttaatt
     7681 ttttattcag aaagtttacg aatacatcaa aattctgaaa caaaaaacgt aactcacaaa
     7741 gagttgtttt tgcgtttttt cttgaatgat taggtctgaa tcttttgctc acaaccttat
     7801 tcatggtgcc ccggcttgag ctgatagatt tttgaaggac ggccgattcc tacaggacgt
     7861 tcaccgatct catcgaaata ttggagcata gctttcttaa aattggaatg atcgatcgtt
     7921 ttataatcga tccctaagaa tttagcaaat acttttcgag cttccgtaat cgtgaaatct
     7981 ttacctaaaa cttgtagaac ttgcggctcg tgttccattt tattgactac acggttgaat
     8041 gctttcaaga tgatttgact atggtcaaaa gccaaagtat ctttgccaga agactctcca
     8101 gtgactaaat caagcgagat agccacttct ccgctagata aatggatctt gttactatga
     8161 cgttctagtg tgaaccagcg tacttccttg gcatcatctc cggcgattag cggttcttct
     8221 ccaataaagg ctaagtagct gactgtgacg acccagcctc gcggatctcg attaggcgta
     8281 ctgaatgtat gcagttgctc aatattttct tttgaaataa ccacaccagt ttcttccttt
     8341 gtttctctta agacgctttc tccagttgac tcatcctttt ggacaaagcc accaggcaat
     8401 gcccatgaat ttcgataagg atgccctttt ctttggatca acaaaacttt cagctgatct
     8461 tcttctttgt tatagcacat cagtacgata tcgacagtca aagagggctt gtcatattct
     8521 ggacgttcct gtttttgata ccagttaaga aattcttctt cacttgcttt atgttcataa
     8581 tataattttt cttcttcttt agaagcaaaa cggttcatct gaccacctcc attgacagta
     8641 aaagtacttt ttaccttatt gtagcagact ctgaaaaaaa accaaggatt tacttgaaaa
     8701 atctaggtta tcatttaaat atgaaaaata aatggaagta tgagattgaa taaaaagaaa
     8761 agcagataaa acggcaatac tttataccgc tcttcacgaa tggcaaagaa gccacaaata
     8821 acgatatata cgtcaatgat aaaacgcaaa atccaagctg ctgtcataaa actgttcaaa
     8881 tgcccatgga ggttaaaata accatacata cgaatataaa aatagctgaa tattaaatgt
     8941 gctaatgaaa gaaaagcaat actaagtgta aaaaaaagat gtttcttctg catgattgtt
     9001 ccagtccctt actaagatag atagtcttta ttataccacg tgtgagggga gaaataaaaa
     9061 gccgtttttt agtagatatg aaacaaaaca aaaacccgca tttattcaac ctattcatcc
     9121 ttttaaagga tagattgaac gtagatagaa gtcgtttatc cagtcttttt cattttgaaa
     9181 aaaagctaac agcatgcttt ttttatggta tactagcaag gaaacgaatt cgcatcatgc
     9241 gataaaggag gaagagcccc gtggcagaaa aggaaacttt ttatatcact acgccaatct
     9301 attatccaag cggcaaactt catatcggca actcgtatac tacgattgca tgtgacgcaa
     9361 ttgctcgtta taaacggttg atgggctttg atgtgtttta tctcactgga gtggatgaac
     9421 atggtcaaaa aatcgaaaca aaagcagaag aactaggtgt aaaaccgcaa gaatatgtag
     9481 ataaaatggc ggctgatgtc aagaaattat ggaaaacgct tgatatcagt tatgataaat
     9541 tcattcgcac gacagatgat taccataaag cagctgttca aaaaatattt gatcgtttat
     9601 tagaacaggg agatatttac ttaggtgaat atgaaggctg gtactctgtt tctgacgaag
     9661 aattctttac agaaacacaa cttgcagaag tgtacaaaga tgacgaaggt aacgtgatcg
     9721 gtggtaaagc gccaagtgga cacgaagtag aattggtaaa agaagaatca tacttcttcc
     9781 gcatgagcaa atacgcagac cgtctattgg aatactatga agaacatccc gaattcatcc
     9841 agccagaatc tcgtaaaaac gaaatgatca acaactttat caaaccagga ttagaggatc
     9901 ttgcagtttc acgaacaact tttacttggg gagtaccagt caagagtgat ccgaaacatg
     9961 tggtgtatgt atggatcgat gcattatcca attatattac tgcactagga tatggctccg
    10021 aagatgaaag tctattcgaa aaatactggc ctgcagatgt tcagatggtc ggtaaagaaa
    10081 tcgttcgctt tcatacgatc tattggccaa tcatgctgat ggcccttgat ttgcctctac
    10141 ctaaaaaagt atttgggcat ggctggctat tgatgaaaga cggaaaaatg tctaaatcaa
    10201 aaggaaatgt cgtttatcct gaaatgcttg tggaacgtta tggtttagat gcactccgtt
    10261 attatttgct tcgtgctgtt ccgtttgggt cagatggtgt ctttacgcca gaagattttg
    10321 tttcccgtgt caattatgat ctggcaaatg atctagggaa cttattgaat cgaacgattg
    10381 ctatgatcaa caaatattgt gatggactcg ttcctgacta tgcctcactt gtcactccat
    10441 ttgatagtga actgtctacg acggctgcta acgttgtcgg acgttaccat gatgcaatgg
    10501 aaaaaatgga attcaataca gcattggctg aaatctgggt gctgatttct cgtgcaaaca
    10561 aatacattga tgaaacagaa ccatgggtat tagcaaaaga cgaagaaaag aaagctgaat
    10621 tgaatagtgt catgatccat ttagctgaat ctttgcgtat cgcagcgata ttacttcagc
    10681 caatcatgac agaaacgcca gagaagatct tcaatcaact aggattggac tctgaaacaa
    10741 tgaatcttga aggattacac tttggcgaat ttccttcagg aacaaaagta gttgcaaaag
    10801 gtacaccaat cttcccacgt ttagatatgg aagaagaagt tgcttttatt caagaaaaaa
    10861 tgtctgaagg tactcaaaca aacgaagata cagtcaaatg ggatccagaa gaaacagaac
    10921 ttgtttcaac gaaagaaaaa caaatcaaat ttgatgtatt tgaaaaagta gaactaaaag
    10981 tagcagaagt catcaactgt caaaaagtag aaggggcaga taagttgctg caattccgac
    11041 tagatgctgg agacagccaa gaccgtcaaa tcttgtcagg aatcgctgaa ttttatcctg
    11101 atccaagcga attgatcggg aaaaaagtcg tcattgtagc aaatctgaaa ccacgaaaga
    11161 tgcgtggaca aatcagtcaa ggaatgatcc tttctgcaga agcaccagat ggctctttac
    11221 aagtaatcga agcaccaaaa tccatgccaa atggctcaga aatcgcatag aaattcaaag
    11281 ggggtatgac actagttgtg tcataccccc tttttccgaa atttgagaag caattttcgt
    11341 aaattccttc ttattacttg aagccaatca tataatacag aaacagagaa ctatccaaaa
    11401 taaatcctag aaaaagaagt acgagcttcg ctgatttttg ttaatttaga ataatactaa
    11461 taggaatcgt aaaaacagaa aaaaagcata atgataaagg gtcgggcaga ttttaattga
    11521 ttcatctggt actctttttt attgtcctta cattcataaa gtttgaatgc aatgacttta
    11581 ttacatctat atttatatct aacagtagcg ttgatgtgtt aattataagt tctatcactt
    11641 tatgttcaat tagtttgtgc tcttatatgt gtgattgaaa atatagataa aaaaacaatc
    11701 atcggctttg acttcgatga ttgttttctt tattttgtaa aaatcctatc acttgatttt
    11761 atggtaacct tttatttttg tcttcaaacg gcttggtaag agagcagtaa gcagtgcaaa
    11821 tgggatcgaa aagacatacc agaaaatcgt acgtccgata ccataatgtt gatagagctt
    11881 tgtcaacatc acgtgtaaca agatcaaccc taaaagcaag gagccagcta taaaccaatg
    11941 attatcccaa tgcatgactt cactaagtgc catcactcca aaaggataga aataaaaata
    12001 gatcccgact aaggtcatcc gccagttctt tgtaaatgtt ccgatattca ataaaaagaa
    12061 aatcgctgaa agcaaaatac cgataggcgg aaaaagccca accaaaaagg aatacaacat
    12121 cccccacaag atcatcacag gacctttgat caatgcaacg attgcgatga acaaagtcag
    12181 caatattagt ttttgtgata acgttgcaac agtcattaat ccaaataaaa ttaatgtgaa
    12241 ccaatgccaa tgggactgct gttgttcttt acgggaaaaa tcgacccggt tggataaata
    12301 atctgctaat ttcggataag aacgcttaaa atccataaac tgttcctcct tcgtggaaaa
    12361 ggtaggttta gtatacgaaa aataaaaaag aaatacatcc gtcttaagag ggagtttttc
    12421 actgaaagtg gagaaaaaag aatggtaaat taaaatattc tcagttatac tgaaaattat
    12481 accaaatttc aaagaagaaa gaggatggga atgaaaggca aactaaaacg agaaatcaat
    12541 ctgtttggcg cattagctac cgttatggga accgtgatcg gtgcaggcgt cttcttcaaa
    12601 actgctgctg ttactgctag tactcagtct acaagtttga cattgctagc ttggcttttg
    12661 ggtggtttct taacgatctg tgctggattg acagtggctg aattagctac agcaatcccg
    12721 gaaactggtg gagctgtaaa atatattgaa gctgcgtatg gaaaattgcc cagcttttta
    12781 ttaggatggg cgcaaagctt gatttacttt cctgctaata ttgctgcatt atcgattatc
    12841 tttgcgacac aattgacgaa cttattacaa ttatctaccg attatctttt gttgattgca
    12901 gtgatcaccg ctgtttctgt gacagggttg aatttgttag ggacaaaagt cggtgcttct
    12961 gtacaatcag tgacgttgat tgttaaatta ataccaattg ctgtgattgt catatgggga
    13021 ttattgaccc caggacaagg aactgtccag ttatttccaa tcgaagctgg aaaagatgtt
    13081 acttttgtcg aaggattgag cagtgcgttg ttagcaacgt tgtttgctta tgacggctgg
    13141 ttaggtgtcg gtgcaatggc aggggaaatg aaacggccgg aaaaagattt gcctaaagca
    13201 attattcttg gtttgagttt tgtaacagtc gtttatctat tgatcaattt tgtttttttg
    13261 aaaactttgc cgattgatca tcttgccggt aatttgaatg cagcttctga agcatcagac
    13321 gtcatttttg gaggaatcgg tggaaagctg gtcactattg ggatcttgat ctcggtatac
    13381 ggtgcattga acggttatac actaactggg atccgcgtgc cttatgcgat ggctttagaa
    13441 gacgagctac ctttcagtaa acagctgaca aagctttcaa agaagtttac ggttccttat
    13501 gttcctgcgg ttttccagtt agcagtagct tgtattatga tgagccttgg ttctttcgac
    13561 tttttaacag acatgttgat ttttgtgatg tggctattca gtttactgat ttttatcggt
    13621 gtctttattt taagaaaaaa agcgccggaa ttgccacgtc catataaagt accactttat
    13681 ccaatcgttc cgattattgc gattctcggt gctattttca ttttaggtat gacgatgatg
    13741 acgcaaacga aattagcatt gatcggtata ggtgttacct tgataggtat cccagtctat
    13801 tatcaaaaaa agaaaaaacg ctcagaagag taaaatattt caacaacaga cagaaaaagt
    13861 acgaactagg tcctctagat cttcgtgctt tttctatttc aataaaacaa gttcttctat
    13921 tttgattttt gctacttctg caagtagtgc ttatgtgcta aagtaagaat gaaaaggaga
    13981 gataaacatg atatttgatt ctcataccca tttaaatgct gaacagttca atgaagatat
    14041 tccagaaacg attcagcgag cacaagaaat gggggtaacg aaaatggcgg tcgtgggctt
    14101 cgatacgcca acgattgaaa agtctttgca attaagccat gactatccaa atatatacag
    14161 tattatcggc tggcatccga cagaggctgg cagttatacg aaagaaatcg aaaataaatt
    14221 acaagaacaa ttgactttac caaaggttgt agcattaggg gaaattggct tggattatca
    14281 ttggatggaa gacccgaaag aagtccaaga taaagtattt cgcagacaga ttgctatcgc
    14341 aaaagaaatg aacctaccaa tcagtattca tactagagaa gcacttgaag acacgtatca
    14401 aatcctaaaa gaagaagatg ttcgagatat cggtggaatc atgcatagtt tcagtggtga
    14461 ttatgaatgg gcaaaacgat ttcttgactt agggatgcat atttcattta gcggtgtcgt
    14521 cactttcaaa aaagcattag acgtccaaga ggctgcagca aatgtaccaa tcgaacgatt
    14581 acttgtggaa acagatgccc cttatctggc accagttcct tttagaggaa agcgaaatga
    14641 accaggctat actcgttata cagtagaaaa gattgctgaa cttcggaatc ttccgacaga
    14701 agaagtggct gcccaaacat ggacaaatgc gcaccgatta tttggtctaa gcgaacatgg
    14761 ataagatgaa gatccaagag attatagtcg ttgaaggaaa agacgataca agaaggctgc
    14821 gggaagtagt tgatgcagat acgatagaaa caatagggtc tgcaatcaat gaagagatcc
    14881 tgatgcaaat tgaacatgcc caagagactc gtggagtgat cgtttttacc gatcctgatt
    14941 tttcaggaga aaaaataaga aaaatcatta tggaagctgt tcctcaggca aaacatgctt
    15001 ttttgccgcg cacacaagct aaaccaaaga aaaagggaag ccttggtgtc gagcatgcaa
    15061 gtgatgctgc tattttagaa gcattgaaaa aggtcgtgac gccagacatt tcccaaacgg
    15121 ctgtttctga aatcactaga caagaccttt tagactatgg tttaatagct ggggcacaag
    15181 caaaagaaaa acgagaaaaa ctaggtgacg agttgcgcat cggttacacg aacggcaaac
    15241 aattggaaaa acgtttgaag atgtttcgta ttacgccgaa agaactcgcc caagcaatga
    15301 aaatagtgga ggaacaacat gagtgaatat cgtgaaattg cgacaccctc tagaacaaaa
    15361 gagattttat tgaaacatgg tttttcattt aaaaaaagtt taggacaaaa ttttctgact
    15421 gaaccaaata ttttaaggaa aatcgtagaa actgcgcaaa tagatgaaca tacgaacgtg
    15481 atcgaagttg gaccaggaat cggtgcattg acggaacaat tagccaagca tgcaaaacaa
    15541 gtcgtagcat ttgagatcga tgatcgtttg atccctgtat tggctgatac gatgcaaccc
    15601 tatgacaatg tgactattgt acatcaagat attttaaaga ccgatttgtc aacagctgtt
    15661 agagaaacat ttcatgagga gcttccgtta aaagtcgtag cgaatttacc ttactatatt
    15721 acgacaccga tcatgatgca ttttcttgaa tcagatttgg ttgtggatga actagtcgtc
    15781 atgatgcaaa aagaagtagc tgatcgtatc tctgctgaac caggaacgaa agcttatggt
    15841 tcattatcga ttgctgttca atattatatg gaagccagtt tagcattcat cgtaccaaaa
    15901 acagtatttg tccctcagcc aaatgtagat tcagcgattt tgaaactgac aagaagagat
    15961 ataccggcag tcgaagtgac agacgaaaaa gcatttttcc gattgacaaa agcggcattt
    16021 cagcaaagaa gaaaaacgct ttggaataac ttgcagcatt cgtatggcaa agatgaccag
    16081 acaaaagcat ggttagcaaa aagcttggaa acagctggaa tcgatccaaa acgtcgtggg
    16141 gagactttgt cattacaaga attcgccgca ttaagcaatg cgatgtcaga aaatatgcag
    16201 taaaaaaaga ggttgtgaca gaagttgtga aaaagctgtc ctgcatcaag taataagaac
    16261 agccaaacaa aaatagttcc tcatgttttt cgtttgtttg ggcttattac cgcagatgca
    16321 agcttttgaa caccgtttaa gaaagaggtt gtgggcctgc cgtttaactc taagtcacaa
    16381 ggaacaattt caaaaaacag cttctcatgt ttttgagtta gttggtctta ttacttgatg
    16441 caagcttttg accactatta tgccgaacaa ggagatgtga cacaaatttt gtcacatctc
    16501 ctatttttgt ttcttgatca aaaaattctt atacttgata ctcacactca ttttgtatgg
    16561 atttagaaaa gaatatgtgt cttgacagtt attagtaagt gagttatact aagtcgacat
    16621 ttatgtgtca agacatatta ggagagagaa aaaatgagaa aaaattcagt tcgaaaacta
    16681 acgatttctg ctttattgat tgggatgggg gtcattatcc caatggtcat gcctaaaatc
    16741 atgattccac cagcttcctt tactttggcg tctcatgtgc cattatttat tgcgatgttt
    16801 tttacaccag gagttgcagt ggctgttgcg ctaggtacga catttggttt ctttttaaca
    16861 acgccggtta tcatcgcatt gcgagcattg tcacatcttg tgtttgcgtt gattggggct
    16921 tggtacttgc aaaagcatcc gagtatcgtt ttaaaaaatg gacagtttac ttttgctaat
    16981 tggcgtttcc aagggttcaa ttttgtgatc ggtgtgattc attctttagc agaaatgcta
    17041 gtagtcagca tcttttactt tattggtaat atgcctgaaa catattattc tcaaggatat
    17101 ttttatacag tattcatctt gatggggatt ggtgggctta tccacagttt agttgattat
    17161 aatattgctt attttatagc aggaacactc agcaaatatt ttgatatccc cgtatttacg
    17221 gcagcaaaaa aagaaaatcg gaaagagtcg attcaagggt acgcgaagaa aacgacatat
    17281 tagacatgat ctctcaaaaa aaaaactctc atctagtaat ggataataaa tcctctaaga
    17341 tgagagtttt ttgtcctaaa aagagctgca ccaacatctt ctggcacagc tctaacaggg
    17401 ggcaatttat ggaagtttga tgacttgttc tgtttcttta tcaaagaagt ggcctttgct
    17461 gatgttgaag gcaaggtcga ctatttcgcc tggtttatgg aaatctcttg catctacttt
    17521 tgagatgaac tcagtagaac cagtttttgt gtaaagcatc gtttcagctc caagtaattc
    17581 ggaaacgaca acttctgatt tcactacggc ttcaggtgaa gcttcaaggg ctacttgttc
    17641 actgtggatg tcttctggac gaataccgaa gataacttct tttccttcat aacctttttc
    17701 aactaatact ttgttttttc cttcaggaat acgaagctta agcccatgtc catctgtgat
    17761 aacaccattt ttcaatgtca cattaaagaa gttcatggca ggagatccaa taaagccggc
    17821 aacgaacata ttgacgggtg tatcataaac ttctttcggt gtaccgattt gttggataaa
    17881 tccgtctttc atgataacga ttcggtcagc catagtcatt gcttctgtct gatcgtgagt
    17941 aacatagatg gtcgttgttt caagacgctg gtgaagtttg gcaatctcag cacgcatggc
    18001 tacacgtaat ttagcatcta aatttgataa tggctcatcc attaagaaga cttttgcatc
    18061 ccgaacgatt gcccgtccca atgccacacg ttggcgttgt ccaccagata aagcagctgg
    18121 ttttcgtttc aagtattctg tcagacctaa gatctctgct gcattgtcca cacgtttttt
    18181 gatgtctgct ttatcatatt tacgtaattt caagccaaaa gccatattat caaaaacagt
    18241 catatgagga tacaatgcgt agttttggaa aaccatggca atatcacggt ctttaggtgc
    18301 cacgtcattc atgacttttc cgccgatatt tagttctcct tcagagatat cttccagtcc
    18361 cgcgatcatt cgcaaagtag ttgactttcc acaaccggaa ggaccaacaa aaacgataaa
    18421 ttcacggtct ttgattgata gattaaaatc agttacagaa taattttctg cattgtcata
    18481 ttttttatat acgtttttca gagccatttc taccataata cgttccacac tttctttttt
    18541 agttttatta actatttaaa gtataaatga aagcgttaac taacttcaat gtcatgttga
    18601 acaagaattt tttctttttt ttgtcaatgt gctagtttta agctttaata aatatccata
    18661 agaaataaaa actgatacac tggagtaaat aagtatgtta acaatatcaa aaggagtgtc
    18721 tcttatgaaa atcgctttga tcgctcatga ccgaaaaaaa cctatgatgg tgaaattagc
    18781 aacagcgtat aaaacaatat tggaaaaaca tgaacttttt gctaccggga cgactgggca
    18841 gaggatcacg gaagcaaccg gcttgccgat ccatcggttt aaatccggac cgttaggcgg
    18901 ggatcagcaa attggagcca tgatttcgga ggatcagtta gatttggtga tttttcttcg
    18961 agacccgctg gctgcacagc cccatgaacc agatgtaaca gcacttatcc gtttatctga
    19021 tgtctatgag attccgttag ctacgaatat cggaacagct gaggtgctac taagaggact
    19081 ggaagccggc ttcctagatt ttcgaagaat cgtccatgaa atagacaagc atccactttc
    19141 attttgatgg ataagcgtat ggaaaaataa cgtttaatgt tcgcctatat gtagctataa
    19201 aagctaaaca aactgataat atgcgatata atacgaacgt attggataat ataaacaata
    19261 atattagttt ttcgtatttg cagtaaatgt gaaaatatgc tatagtttct gtgggaaaag
    19321 atcccaaaaa taatacagag tagaaaataa agcgttaagt gctaagagga tgggatgttg
    19381 cctcttggac gaaggacgta atgttcgcgg ttttattttc gcattcgctg catgatacga
    19441 tgtagcagct cttaaaggag atgctaaaaa tgaagaaaca ccggttagac gcacgtatga
    19501 ttgctattat gggcttattg attgcattga tggtcacttt gtcccgactg gtagcaatcg
    19561 agaccccatt tattaaaatc agtgtcacat ttattccaca agtgatcatg ggcattcttt
    19621 ttggtccttt ttggtcaggg ataggcgcag ttttagctga tttagtagga atggccctct
    19681 tctcgaaatc tgcattcttt attggattta cattgaatgc atttattgaa ggagcaatct
    19741 acggattctt tttctatcga aaagagatca cttggaaaaa tgccattctg gctacgctta
    19801 gtgtcacgct gatcatcaac ttatttttga caccattatg gcttgcgttg atgtaccatg
    19861 tgccattgtt cagctgggtc gtttgggcgc cccgcctgtt aaaaacagta atatggttac
    19921 cgattcaatc aattgccatt tattacgtag gacgtagtat tccttacaaa aaaattttaa
    19981 gaagtttagc gatccacgct aaataaaaaa caagcagtct tcccatccca gaagactgct
    20041 tgtttttatt gtgctgtgaa ttgtgcttga tagagccgtc ggtaataacc atctttttga
    20101 agcagctcat catgggtgcc catttcgaca atagctccct gatccatcac taatatctgg
    20161 tccgcatttt tgattgtgga caggcgatgg gcaatcacaa aactggtttt tccttccatc
    20221 attgctaaga aggcttgttg gatttttttc tctgtcaatg tatcgactga gctggtagct
    20281 tcatctaaga tcaacatagg gggattactg atcatcgttc gagcaatcgt caacagttgg
    20341 cgttgtccat ctgatatctt taacccttga ccgccaatct tagtatctaa tttttccggc
    20401 aaacgttcta caaattcata catataagag gcttttaggg catcattgat ttctgcgtca
    20461 cttgcttccg gattcccaaa acgaagattt tctcgcaatg tactgtcaaa tagccaagta
    20521 tcttgtaaca ccattccaaa acttttacgt aatgtatcac gttggataga gcggatgtca
    20581 tggtcatcga ctgtaattgt tccttttgtt gtgtcataaa aacgcatcag caaattaaca
    20641 agtgtggatt ttccggcccc tgtttttcct actatagcaa tggtttgacc tggataagca
    20701 gtaaaattga aatcttcgat caaacgctgc ttggggtcat aagaaaaaga aacatgatca
    20761 aaagagactt ttcctttgat atttttgggt tccaaggcat aggcatctgg caaatcaggc
    20821 ttttcttctg gctgatcgat caaatcaaat gctcgttcta gaccagaaaa agcggtttgc
    20881 agttgtgtcg tgattccaga aagttcgata aatggtttag aaaactgact tgagtagatc
    20941 gtaaagctgg aaatcacacc aacagtgatt gacgaaccac tcttcaatgc caataggccg
    21001 ccaactaaac caatcgataa ataagcaagg tgatctacaa aacgagaaga cgggtttgtc
    21061 aaggaagaag aaaattgtgc ccgttgtcct ttttcatata gatcagcatt tagcagttca
    21121 aattgctgtt gactagcttc ttcttgctga aaagctttca cgattttctg gttaccgatt
    21181 cgttcggtca caaagcccga gatatcccca ataatccttt gctgtctatc gaaatttgtt
    21241 tgtgaagcac gagcaacgat ccaactcaca aggaaaataa ttggtgtaga acaaagaacg
    21301 accaatgtca gaagtggact tagacgcatc ataaaaataa acgaaagaat gatgattgcc
    21361 actccagaaa ataattgatt gaaggccgca gaaattgcaa tggaaatatt gtccatatca
    21421 tttgtaaatc gactgacgat atttccgtgg gagttttgat cataataacg aagtggcaat
    21481 cgattcagat gagcaaatgc atcttttctt aattttgcaa cggataagta agctaaccga
    21541 ttgcttaaca cttggatgag ccattgactg actacgttga ttaaaacgat accaccgaat
    21601 agaataagta aatggaacag tcgattgaag cggacctgtc cttctccaat catttgatcg
    21661 atactttgac caatttgtaa cgtcatcaca actgttgcaa tcccattgat gattcctagt
    21721 atcacagcta gccaaatgtc ttttgcatag gcagtaaggt aaggaatgaa tcggcggagc
    21781 gtctgcaagg ataatttttt tactttcata actattcttc ctcctgtgat gcgacgattt
    21841 cctgatattc tgctgattga gcaagtaatt cttcatgggt accctgagca gcaatcttac
    21901 cttgatccat cactaagata tgatgtgctt cttgaataga gcggacacgt tgggagataa
    21961 taatcactgt actgccaaga taagtctgta gcgccttacg caaatccaag tctgtttgat
    22021 aatccaacgc acttaaagag tcatctaaaa tcagtaatgc tggcttggca atcaaagctc
    22081 ttgcaatcgt cagtcgctgt ttttgtccgc cagagaaatt tttcccattt tccatgactt
    22141 ttgtatctaa accatttgga agctgacgga caaattcttc tgcctgagcg attttcagag
    22201 cttcccaaca ttctttttct gtggcgtctt tcttacccca ttgaaggttt tcacgaatag
    22261 tcccggtaaa tagtacagaa gtttggggaa caagagcaat ttgctgacgg agatgatcca
    22321 gctgccaaga acgaacatcc attccgtcca ttataactgt accggaactg acatcataga
    22381 aacgcggaat caattgtgtc aaagtcgttt tcccgcttcc ggttggacca atgattccaa
    22441 ggactgtatt tcgcttcagc tgaaatgtaa tattttggag agaaagacca gaatcaggag
    22501 tataacggaa gtcaacatgg tcaaaagcga taattgcttc agaagaaaaa tcgggagtag
    22561 tactgacctc agcttcaaga atcgaatttt ctgtgtctag cacctctttc acccgatttc
    22621 ctgaagcttc ggcacgtgtg aagatcacga cgaggtttga aacaacgatc agtgccaaaa
    22681 gcatttgatt catataattg atcaaagcaa gaacttgtcc ttgttgcaag ctaccaatat
    22741 ttactttgat cccgccaact gtcagcaaac agatgatccc gacattcatg atcaaggttg
    22801 tagcaggtga taatagggca gagatattgg aaacacgtaa ataattgttc gctagatcat
    22861 ttgtgctttt atcgaacttc tctgtttctt tttttgtctg cgcaaatgcg cggatgacac
    22921 gaacaccgct aagattctga ctaacgtgtt cattgagctg atctagtttt tcttgcactt
    22981 tttggtagag aggaacggtt tttttgatga taaaaaataa aatgattgag aaaataggca
    23041 ataatgctaa gaaaaacaga cctacttccc agtcgatcac aaaagccatg accactgacc
    23101 cgatacttaa aaacggtgct ctgatcaata aacgaatgac cattgctaaa gctagctgaa
    23161 gctgattgat gtcgtttgtc attcgggtga tcaaggtatc tgttccaaaa tgattcaact
    23221 cgttgtgaga gaaagtattg atttttttga ttagctgatt acgtaactct gtaccaaatc
    23281 cttgtgaagc tactgaagca tagtattggc aaatgatagc acaaatcaga ccaatcacag
    23341 acatagcgac catccataag cccatttcaa tgatttttcc tcggtcattc atttttagtc
    23401 cattatcgat caaggaagcc atcattaaag gcaggacaag ttcgaagaca gcttcaagaa
    23461 atttgaagaa cgggcccaaa atgatttgct tacgatagtc ttttgcataa cgtaataact
    23521 gaatcatatg attcctccta ttatttattt gtccacaatt gaaaaaacaa gtactaccac
    23581 attgtagctt aggaaattta gaatgaaaag agaacaagcc ttttcataaa tgaaagtttt
    23641 attatgaaga agctttagaa attgaataga ctattttttt taaaaaaaag aaaatga
//
LOCUS       DAZKNV010000042        23673 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000042 DAZKNV010000000
VERSION     DAZKNV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.042"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            290..697
                     /locus_tag="ACG8M1_001874"
     CDS             290..697
                     /locus_tag="ACG8M1_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422559.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            711..1112
                     /locus_tag="ACG8M1_001875"
     CDS             711..1112
                     /locus_tag="ACG8M1_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422560.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1114..1485
                     /locus_tag="ACG8M1_001876"
     CDS             1114..1485
                     /locus_tag="ACG8M1_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422561.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1521..1823)
                     /locus_tag="ACG8M1_001877"
     CDS             complement(1521..1823)
                     /locus_tag="ACG8M1_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0422562.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2081..2194)
                     /locus_tag="ACG8M1_001878"
                     /pseudo
     CDS             complement(2081..2194)
                     /locus_tag="ACG8M1_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2577..3809)
                     /locus_tag="ACG8M1_001879"
                     /pseudo
     CDS             complement(2577..3809)
                     /locus_tag="ACG8M1_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
     gene            4063..4632
                     /locus_tag="ACG8M1_001880"
     CDS             4063..4632
                     /locus_tag="ACG8M1_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0422563.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4810..5250)
                     /locus_tag="ACG8M1_001881"
     CDS             complement(4810..5250)
                     /locus_tag="ACG8M1_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFQ0422564.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5408..6172
                     /gene="map"
                     /locus_tag="ACG8M1_001882"
     CDS             5408..6172
                     /gene="map"
                     /locus_tag="ACG8M1_001882"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFQ0422565.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6204..7127
                     /locus_tag="ACG8M1_001883"
     CDS             6204..7127
                     /locus_tag="ACG8M1_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFQ0422566.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7203..8342
                     /locus_tag="ACG8M1_001884"
     CDS             7203..8342
                     /locus_tag="ACG8M1_001884"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFQ0422567.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8335..9135
                     /locus_tag="ACG8M1_001885"
     CDS             8335..9135
                     /locus_tag="ACG8M1_001885"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0422568.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9135..9962
                     /locus_tag="ACG8M1_001886"
     CDS             9135..9962
                     /locus_tag="ACG8M1_001886"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0422569.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9967..10674
                     /locus_tag="ACG8M1_001887"
     CDS             9967..10674
                     /locus_tag="ACG8M1_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0422570.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            10774..11640
                     /gene="rfbA"
                     /locus_tag="ACG8M1_001888"
     CDS             10774..11640
                     /gene="rfbA"
                     /locus_tag="ACG8M1_001888"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFQ0422571.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11654..12226
                     /gene="rfbC"
                     /locus_tag="ACG8M1_001889"
     CDS             11654..12226
                     /gene="rfbC"
                     /locus_tag="ACG8M1_001889"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFQ0422572.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12248..13276
                     /gene="rfbB"
                     /locus_tag="ACG8M1_001890"
     CDS             12248..13276
                     /gene="rfbB"
                     /locus_tag="ACG8M1_001890"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFQ0422573.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13374..14225
                     /gene="rfbD"
                     /locus_tag="ACG8M1_001891"
     CDS             13374..14225
                     /gene="rfbD"
                     /locus_tag="ACG8M1_001891"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFQ0422574.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14260..16293
                     /locus_tag="ACG8M1_001892"
     CDS             14260..16293
                     /locus_tag="ACG8M1_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422575.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16337..17617
                     /locus_tag="ACG8M1_001893"
     CDS             16337..17617
                     /locus_tag="ACG8M1_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFQ0422576.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17827..18633
                     /locus_tag="ACG8M1_001894"
     CDS             17827..18633
                     /locus_tag="ACG8M1_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422577.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18645..19865
                     /locus_tag="ACG8M1_001895"
     CDS             18645..19865
                     /locus_tag="ACG8M1_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422578.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19855..21441
                     /locus_tag="ACG8M1_001896"
     CDS             19855..21441
                     /locus_tag="ACG8M1_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0422579.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21480..23618
                     /locus_tag="ACG8M1_001897"
     CDS             21480..23618
                     /locus_tag="ACG8M1_001897"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0422580.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7568 a         3938 c         4854 g         7313 t
ORIGIN      
        1 ttttgagggg aagtacatat agttgttgat atagttgcta atattgttag ctaatttgtt
       61 agtaaaactg tatacgaatt tagatagtaa aaaaacagtt tgttccttat atagaggcac
      121 ttttactact gattaaatgt cagatatgct tacaaatata cttataaata tgcttacaaa
      181 attagctaat atttccgttg acaaagcttt gttactattg ttaaactaaa ttgactagca
      241 aaagtgaaac ataaatttat taaataaatg taaaaattag gagaaatcaa tgtcttatag
      301 agtacaatta ataatttcag aagatgtaga aagtcagcaa tttggcacta atgttattaa
      361 taaagtaatt aatccagctc tttctattaa tgcgccttta attcctactg ctttatcatt
      421 ttctgtaaca gctgtggtgt ctgagataga ggatacagaa aagataaaaa tagtagaaat
      481 tgaagtttta aacaagaatg aaaaacaaat tttttctacg ggtgaagtat cggtaagctt
      541 gcctcctcaa gttaacgata taaactttaa tataaacgcc agaaatgtct tggttgaaga
      601 agcaggagag cattatgctg ttgttaaatt taatggaact gagattggaa ggcaaatctt
      661 tgatatcaag gtcaacaaac cagtggaaaa aaattaagga gacgatacgg atgcttgata
      721 tagtaccatc aaatacacat cggagtggta gcttaataaa ttttgctgcg atttttgctt
      781 gcgcatcggt aattctagca tctccagttg ttgtggatgc aagttctact ccgaaaacta
      841 aaaatgataa tcaacttgta attactacaa aaaatgagat taacacaatt tcaagtaatg
      901 atggcaaaat ttttgatgtg ataaatacgg ttttaaaaag aaaagctgaa atcaatataa
      961 aatatgatga agatttaaac ttgtatttct ttgttatcaa aacaacatct gaattgtttt
     1021 cctcagatta cgatgttttg gatactctcg ataatgtatt atctgactat aaatatatgg
     1081 ggaaatctgt agtagcaact ttgggggaat aaaatgtttg actttaatga atatttatct
     1141 atttccaaac aaattgaatc agatgataaa tataattcta aagaatctta tagaagaact
     1201 gctgtttcaa gagcatacta cagtgctttt aaaaaatctg atgagtattt gaaagaaaat
     1261 tatgatatta tttataatgg aagtagcgga aaaggaagcc accaaaccgt ttggaatttg
     1321 ttttcaacag ttaaggaatt gaatacctta ggaatacata atagtgggta tagaatgtta
     1381 gagaaaagaa aatgtgctga ctatattcct aatgaaacca ttacgaaaac agatatggcg
     1441 ctgatgaatc gagaagcaga aaaaataata aacaaactca cctaatgaat ttcaagcgag
     1501 tttgtttgtt atttttttat ttaatctttg tatctttctg gatcaacgaa agtatacttt
     1561 atatagtcat aacgccgatg atcgctacgt gcgtccggca cgtcagtcac gatatcaaac
     1621 aaaaagtata cacccttctt cattctagtt ttcgcagcgg gaattttgaa atagttctta
     1681 ttagaatagt agagattgat taataagcta tcttcgattg ctaaaaagaa aacttctgaa
     1741 ttccatactt tataaaaatc tttgataaat ctattcgaag ggtcaaattt aaaccataat
     1801 tgtgtttttc cttccatcag cataaaagtt cacctcaaaa agagtatacg aacgaatgtt
     1861 ctttttgtga aggcggaatt taatatactg aataatagaa aacaagtact tgtgccaaat
     1921 tatgtgccaa aaaaattcga attcaacaaa atgtaaacaa atagaaaacc ttctatatta
     1981 agatttcctg caataacaaa cacaacagaa gacgtgtaat agttagtcag gaacgtacaa
     2041 ataacccctg tatcctttgc ggtacagggg gttattttgt ataagtagac attgtagttt
     2101 ctaaactgct atgtcctaaa cgtttcgata cgctaagtat atttactcct tgataaagta
     2161 aaatagatgc atgcgtatgt cttagtccat caataaacag tcgaagagaa aatagggaaa
     2221 aattgattac taaagaaaaa cttactaggt cgacggtgta gttgattttc atacttcaat
     2281 agattcgaat taaacgattt cgattggctt ataccagtcc tatccaacga aagatatatc
     2341 gttcttaact ctagcggtat aacttgaagc tttacgtaaa gccaatggga atgaactgga
     2401 gatgactttt tattattttt agtaatagct gatgggttaa tacttacaac tttccttttc
     2461 aaagtaccat ataaaaaaac ggtggggttg tttagcgaaa taaaggatct aagccaatag
     2521 cttagatcct ttattctatg ctttatatta ttttttgcat gtgtgcgaaa gtatactcaa
     2581 gcccaatcgc catttcggaa aatcggtact gtagagccat cttcacggat tccgtcgata
     2641 tccatcttgt cagatcctac catgaaatct acgtgggttt gacttctatt caatccagct
     2701 tctgctaatt cttcatcgga catttctgta ccgcctttca cactgaaggc ataagcagaa
     2761 cctagtgcta agtgattcga tgcgttttca tcaaataatg tattgaaaaa gatgatgcca
     2821 gattgagaaa taggtgaagg gtcaggtaca agtgcgactt ctcctaaacg acgcgcacct
     2881 tcatctgtat caagcagttt tgctaagaca tcttctcctt gttcggcaga aaaatcaaca
     2941 acttttccat ctttaaaagt aaatttcata cccgagatga tggtgccagc ataactcagt
     3001 ggctttgtac ttgaaatgta accatctact cgatgactgt caggtgctgt gaacacttct
     3061 tacgtcggca tatttgccat gaatttttct ccacgagcat tatagcttcc agcgccttcc
     3121 caaagatggt ttttaggcaa tccgataatg atatctgtac cgggagcagt atagtgaagg
     3181 gcagaaaatt gttctcgatt caattcttct gctttttttg ctaatttttc atcatgcttc
     3241 ttccatgcta agacagggtc ttcttcatag acacgagtcg ttttgaaaat ctgatcccat
     3301 aatgcctcaa cttgtttttc ttctggcagt tctgggaaga cttttgctgc ccattgttta
     3361 ccagccgcag ccacgacagt ccaactgact ttatttgctt gagttgcctt gcgtaaattc
     3421 attagtgctt tgccattcgc tgattgataa gacgctactc gatggctatc tacaccagca
     3481 aatgcatcgg gatcggcaga aacaacgctg atcctgcttg ctcctttttc aagccattca
     3541 tccgcttgat cgattttaga ttgtggtaca ttctcaatac gatccgttgc agcatgtaaa
     3601 agaaattctc tttggatctg gtcgtcagtc cattgaacga taacctcagc ggctcctagt
     3661 ttataagctt cttgtgtgat caatcgagca aggggtgcct gttccacgct gatctgtaaa
     3721 acaactgtgt gtcctttttc tgtggctacg ccagtttctg caattaagcg tgcatatttt
     3781 tttagaagtt cattaaaatc agataacata ataaaaattc ctcctcacca ttttttctgg
     3841 taactattag catgatacca tttaattatg attcaaacaa tgaggcttta aataaaaaaa
     3901 ggaggttatt tttttaaggt taagtttcat gatatatgtt actacttgct atttcagctt
     3961 gtgaagaaaa tcaaaaacta attttgcata tcaaaaaaac atgttacaat gaaattaatc
     4021 aatggtggaa gcgttataaa aaaattaagg agattaaaaa atatggcaag aaaaaagacg
     4081 attactagag aacagatttt ggcagctgct tatgaagtag ctgccaccga tggatttaca
     4141 cgatttactg cgagaaacat cgcgaacaaa atgaattgtt ccacgcaacc gatttatctt
     4201 gagtttaaaa atatggatga cttgagacaa gctctttttg agcagatcta tgatcattta
     4261 caatatgaag tgttcactgt tgagcataca gggaatacga ttatcgatct tgcttttaat
     4321 tatatccatt ttgcaagaag agagaagaag ttgtatcgtt cactgtactt agaagaatat
     4381 ggtggaggaa aagagatgca gaatttctct tatacttact ttgtgaatac agtgaaacgc
     4441 gatccagctt atgtgaatct ttcagaagag cagatcgaat ctttgtataa tgggacatgg
     4501 atcatagcta ctgggatcgc agctttgatg tcttcaagca tcatccatcc aactgatgaa
     4561 cagattgaaa agatgatcca agacagtata gatgctatct tgaaattcaa agaaccaatc
     4621 gaaatcgatt gaatatactc aaaagttcca caaatcagta ggtaacaaga gatgtgtcaa
     4681 aataaggaaa agttcgtttt tcttacagcg tatgcatttt taactcccga agaactcttc
     4741 catgaatgca atgaataaaa gagccataca gattgaataa atctggatgg ctcttttatt
     4801 gcaagtatat taaatttttg cgactagttc tttagcgaaa gcttctaaat tttcgatatc
     4861 ttcttcttca gcattcagat ccactttaac attttcggct ccttttgatg cgcctgtttt
     4921 tgcaaaagca gcatcgaaat catccaccga tttgcagaat tcatcgtaaa aagtatcacc
     4981 agatccgcag acaccgtaaa tttttcccaa tagatccaat tcttgcaagt cttcataaaa
     5041 gtctacgatc tcatcaggca gatcgccatc atcgtatgta taagtagcta ctacgcaaat
     5101 atctgcctcc tcgaattcat ctgcatctac ttgggtacat tcgttgattt cgacttcgat
     5161 atccagattt tcaaatgctt ctgcaacaat atcggcgatt tcttcagtgt ttcctgtcat
     5221 gctagcatat acgatttttg ctaaagccat gatgtgcctc ctcgtttata attatttaac
     5281 aattatgaat tataccaaaa catcattgaa aagaaaataa aacctaaaga cacctgggga
     5341 atgtcatttg gctaaatgta tgccgctatg ttaaaatgag agggatttgt aaaaaggaga
     5401 cgaaaatatg attactttaa aatcagcacg tgaaattgaa atgatggcag aatctggagc
     5461 tttattagca gatgtacata aaaatctgcg tgattttata aaaccaggaa tcacaagttg
     5521 ggatattgag gtatttgtca gaaactatat cgagagtcat ggcggaattg ctgcgcaaat
     5581 tggctttgaa gggtatgaat atgcgacttg tatcagtata aatgatgaaa tttgtcatgg
     5641 attccctcgt aaaaagcctt tgaaaaacgg tgatttggta aaagtcgata tgtgtatcga
     5701 tttgaaaggc ggcatttctg attcttgttg ggcctatgta gttggagaat ctacacctga
     5761 gatcgaccga ttgatggaag taacgaagaa agctttgtac atcggtattg agcaagcaca
     5821 agtagggaat cggattggtg acatcggtca tgctatccaa acttatgtag aaggcgaaaa
     5881 tctagcgatc gttcgtgatt ttattggtca tggcgttggt cctacgattc atgaagaacc
     5941 agcagttcct cattacggag aagctggaaa agggttgcgg ttgaaagaag gcatggttat
     6001 cacgatcgaa cctatggtta ataccggaac ttggaaaatg aaaatggatc ctaacggctg
     6061 gactgcgtat acaagagacg gcggactttc ttgccaatat gaacatacat tggctattac
     6121 taaagatggt ccaagaattt tgacatcaca aggagaagaa ggcacttatt gatctatcca
     6181 gtcaataggt acgggagagg tacatgaaag tttggaacaa aataaaacaa aatgaaaatc
     6241 tgatgcgctt tattgagacg actcaaaagc gcatcactga ttcagaaatg agtacgacct
     6301 ctgtcgtcgt tgcttattat ttactcttgt ctttatttcc attgattatt gcttttggta
     6361 atattttacc gtttctccac atcgatcaag agactgtact gacctattta cgagaagtga
     6421 ttcctgagac cgtttaccag tttatcggtc ctgcaatcaa agaccttttg acacaaagtt
     6481 caggaggctt gttatccgtt tctgcattag cggctttatg gtctgcaagt caaagtatca
     6541 atgctttgca aattgcgatg aataaagcgt atggcgtaga aaatagaaaa aattttttga
     6601 tcgtccgttt cttctcacta attgtcattg tcttgttcat gattgctatt agtggggtaa
     6661 ctatcgttct tgggttggga cagctgattt tggatgctat tcagccaatc gtacaaatac
     6721 ccgtgaactt tatcgatcag ttccaaactt tgaagtggcc aatcacattg gtagctttat
     6781 ttgtcatcat gttcttgatt tatttaattg tccctaatgc tcagttgaag ttgaagacga
     6841 tcattccggg cacgatcttc gctactgtcg gctggatgct gttatcacaa gtgtttagta
     6901 tctatgctag gtattttgca acgaggatca gcggttatca gatcatagga agttttattg
     6961 tactcatgct ttggcttaat tttgctgcta cgatcatcat tttgggcgga atcatcaatg
     7021 cagttgttca agaatacgtg acgggtcatc aaatcaaaaa acgtcgagat ccaagccgaa
     7081 aatggttcaa taaattgaaa actaaatttt ctcataaaaa aaagtagaaa caagagttct
     7141 tattgtaaat ttatatcagt aatttataat aattatgact cttaattaaa gtaggtgccc
     7201 atatgcttgt ttcttttagt atggttataa gattttttct gacaatttta ttatcactga
     7261 tattaacacc tgtattcaaa atcatttcag tacaaacagg tatggtcgac aaaccaaatg
     7321 aaagaagaat aaataaagtt ccaatgcctt cagcgggcgg actgcctatc tttatttcat
     7381 ttgttatatc gactttattc ttattccgta aaattatccc tcaatcgtat attgtaccga
     7441 tcttgattgc ttctttagta atcatagtca caggagtgct cgatgataaa tatgagctga
     7501 cacctaaaca aaaaagtata gggatcttga ttgcttctct tattatttat tttgtagcag
     7561 atatacgtat tgattccttc acgcttcctt ttattggata tatccaacta ggctggctta
     7621 gttttcccgt aacgattttt tggatcttcg gtatcacgaa tgcggtcaat ctgattgacg
     7681 gtttggatgg gctggcggca gggatttcat tgatcggttt aattacgata ggaatcattg
     7741 gatatttttt cctccatgct tctacagtgt atattccagt tgttattttc tgtcttgtag
     7801 caagtattat cggttttttt ccttacaatt tttatccggc aaagatttat ttaggcgata
     7861 caggagctct attcctaggg tttatgatgg ccgtcctttc actacaaggg ctgaagaacg
     7921 tgacttttgt ttcatcgatt tctttgctga tcgtcatggg agtgccggta acagacacgt
     7981 tttttgctat cattaggaga aaagcaaacc gtgtttcttt ttctacagca gataaaaaac
     8041 atcttcatca ccgactaatc agtttaggct ttactcataa aggtgctgtc ctgacgattt
     8101 atgcgatggc tttgatgttt tctttcacag ctatggtcat gaattatact ggaagaatcg
     8161 gaacgatcat attgattatt gccatgttgt ttgctgcaat tttattattt gaattgattg
     8221 gtctgatcaa tgagaaacat cagtttattt taaaaacatt gcgattttta gggaataaag
     8281 agtaccgtac gcaagtaaaa cagaaatatt tgaagaaatg gaaccgtcat atagatgaat
     8341 aacaaattaa accagccgat ccttattagt attgtgacgg caaacagtga taaaattttt
     8401 cggacactag ataattttat ttcaactgta aaagatgaaa cagcagtaaa aatccgaatt
     8461 tttgacaaca attcacttcc cgagtacaaa aaaagactaa cagagtatag gaaatatccc
     8521 tacatcgata tctattttca tgatgaaaat tccggatttg gttatggaca taatcacaat
     8581 ctgatagcta gcgattctcg ctatggcatt atttgtaacc cagatatttt agtggatgaa
     8641 gagacagtta cagcattggt cttgttattg aaagaacatc cggaatgtgc gatgttagca
     8701 cctaagattc ttaatgaaga tggaacaact cagcacctca tccgtgagca gctggctgtt
     8761 tttgattacg ttttgcgctt tgtgcctttc aaatgggtca aaaaaaagtt tgacaaacga
     8821 ctggctgtgt ttgaatgccg aggattgcct actgatgcta atagttatgt acggatgatc
     8881 tcaggtagtt ttatggtagc tgatattgat aaatttaaag agataaaggg gtttgatgag
     8941 cgtttcttca tgtactttga agacaacgac ttgtgtttga gttttgaaaa agcaggttac
     9001 aagttattgt acacaccctt ttatgcagtt atccattttt acgggaaggg tgcgcatcga
     9061 aatgcaaaac tgtttcgcgt gtttttgact tctatgatga aatttttcaa taagtggggg
     9121 tggcgttttt tctgatgaaa ccagaaatat tagtagtcgt tgtgctttat cagcaactat
     9181 tcagtcaatc tccagcttat ggaccattaa gcaaagcact tagcgaaaag caaattcagc
     9241 ttattattta cgataatagt cctcaaaggc agcaaaatga gctgtttgaa aaagaaaata
     9301 tcgtttatca tcatgatccg caaaatcctg gtttagcggt ggcttataat tttgcgttgt
     9361 ctcaagcaga tgaaggaaca cgttgtctcg tcactctgga tcaggatacg aggctagtcg
     9421 acgattattt tgaactattg cgtaaagtaa cctttacaga tgaatgtgtt gctgcagttc
     9481 cgatgatttt ttctgggagc cgacaagttt ctcccctata ttcagatcgt tatatcaatc
     9541 gtacagctca agcagtagaa gttgaaggcc caacagctga acgaatcatg gcaatcaatt
     9601 caggtgttgc ctggtctgtc aaatttctaa aaaagattgg cgggtttaat cctgcttttt
     9661 ctttagattt tttggatcat tggctgtttt ggaaagtgga tcagttggaa aaaactgtgg
     9721 agatccttcc tgtacgaatg gaacatgatc tttcggtttt agactatgaa aaagtttcaa
     9781 gtaatcgata ccgttctatt ttacaagcag aaaatcgatt ttatcatgaa tatgatcaaa
     9841 ggcatttatc cagtcaccga cgacaattat tgttaagaac agctaaacag ttcttgaccg
     9901 tcaaaaaccg gcatatctgg cggatgactt tgcgctcata tgttaagaat tggaaggtgt
     9961 gaattcgtgc gttcggtttg tatagctacc tttaatggag gcagatattt aagagagcag
    10021 ttagatagta ttttatctca gctttcagca gaagatgaag tagtcatttc tgatgatggg
    10081 tcagtagatg atacatggga tatattaact gaatacgcag aaaaagataa gcgaatccag
    10141 cttttttcgg ggcctcgtca aggattgatc gctaattttg gttatgcgat ccagcagacg
    10201 aaaggagatc taatcttttt ggcagaccaa gatgatgttt ggttggagac aaaagtgaaa
    10261 aagatcactg actattttga gcagaatccg gatcagctag tagtagtttc tgatttaatc
    10321 attgtggaca gcgagctgca agagatccat gattcgtatt tttcgtttcg aaattccaaa
    10381 gaaggatggc ttaataatgt gataagaagt cactatattg gtgctggtat ggctttccgg
    10441 tcttctttaa aacccgatat tttgccgatc ccgtcagaag tgccgatgca tgatatgtgg
    10501 attggtttgc tgggaggaaa gaagactggg ttcctaagag aaccgttaac tctgtaccga
    10561 agacatgatt taaacgcgag tgagattgaa acacattcta aattacggca aaaaatttct
    10621 tggcgtgttc atctgattac ggcgttgatc aaacgaaaat ggtttaaacg ttgataaaag
    10681 atgtttaaat ccttaatatt tccatgacaa atataacaat tgatgagata ataacaaagt
    10741 gaaatttgaa atcaaaaagg agagcagata tccatgaagg gaatcattct tgctgggggc
    10801 agcggaacac gtctgtaccc tttaacaaag gcaacatcga aacaattgat gccgatttat
    10861 gacaaaccaa tgatttatta tccaatgtct actctgatgt tggcgggaat caaagaaatt
    10921 ctgattattt caacgccaca agatacacca cgtttcaagg aattatttgg aaacggaaat
    10981 gatttaggac tgcagatcga atatgcagta caagaaagtc cagatggatt ggcacaagcg
    11041 tttatcattg gagaagaatt tattggagat gatagtgtct gcttggtatt aggggacaat
    11101 atttactatg gtggcggtct gtctaaaatg ttgcaacgag cagcttcaaa agatacaggc
    11161 gcgacagtat ttggctatca tgtcaatgat ccagaacgct ttggtgtagt agaatttgat
    11221 gagaatatgc aagctttgtc gattgaagaa aagcctgctc agccaaaatc aaattacgct
    11281 gtaactggcc tttattttta tgacaatgag gtaatttcta tcgctaaagg tatcaaacct
    11341 tcagaacgtg gagaactaga gattacggat gtcaataaag catatttgga taaaggaaaa
    11401 ctatccgtag aacttatggg acgcggattt gcttggcttg atacaggaac acatgaatca
    11461 ttgcttgaag catctacctt tatcgaaaca attgaaaaac gtcagaactt aaaagtggct
    11521 tgtttggaag aaattgctta ccgtatgggc tacatcgata aggaacaatt gctggccctt
    11581 gcacagccat tgaaaaaaaa tcaatacggt caatatttat tgaatttggc cgctgaataa
    11641 ggagtcctta cagatgaaag taacagatac aaaattaaca gatgtcaaaa tcgtagaaat
    11701 ggacgtcttt ggcgatcatc gcggtttctt cacagaaagt tattcaaaag caaaatttgc
    11761 agaacatgga ttgaaatatg actttgttca agacaaccat tcactatcag ctgaagctgg
    11821 tgtccttcgg gggcttcatt tccaaaaagg agaagctgca cagacaaaat tgattcgggt
    11881 agtcactgga gcagttttag atgtagtagt ggatatccgc aaaggtagcc cgacttatgg
    11941 tcaatgggac ggatttatct tatctgaaca taatcatcga cagttgcttg tacctaaagg
    12001 atatgcccat ggattcgtta ctttgacacc aaatgtgaac ttcctttata agtgtgataa
    12061 ttactataat gcagaagcag atgggggcat cgcatttgat gatccagatt tagcgattga
    12121 ttggccaatt gatccatcaa gagcgattat gtcggaaaaa gatcaccgtc atccgacatt
    12181 aaaagaattt gaagcagaaa atccatttgt ttacggagaa atctaagaat taaggagaaa
    12241 ttttcttatg aaaaacatca ttgttaccgg aggtgccgga ttcatcggct ctaatttcgt
    12301 tcattacgtg gtaaacaatc atccagaagt gcatgtcact gttttggata aactgactta
    12361 tgcaggaaac aaagagaact tggccggact tcctagcgat cgcgtagaat tggtcgtagg
    12421 agatgttgca gatgcagaat tagtggaccg tctagtaaaa gaagcggacg cagttgttca
    12481 ttacgcggca gaatcccata acgataattc attaaaagat cctttcccat ttgtacaaac
    12541 gaatatcatt ggtacgtata cacttttaga agcttgccgc aagtatgatg tacgctatca
    12601 tcacgtatct actgacgagg tttacggcga tcttccatta cgtgaagacc tgccaggaca
    12661 tggggaaggc gaaggagaaa aattcactgc ggaaacacca tataatcctt caagtccata
    12721 ttcttctaca aaagctggtt cagatctgtt agtaaaagca tgggtgcgtt cttttggctt
    12781 acgtgcaacc atttcaaact gttcaaacaa ctatggtcct tatcagcata ttgaaaaatt
    12841 tattcctcgc caagtaacga gtatcttaag cggtattcgt ccaaaattat atggcgaagg
    12901 aaagaatgtt cgtgactgga tccatacgaa tgatcattct tcagcagtgt ggctgatttt
    12961 gacgaaaggc agaattggcg aaacctatct gatcggtgca gacggtgaag aagataataa
    13021 gaccgtgatg gaattgatct tagaaatgat gggccaacca aaagacgcat acgaccatgt
    13081 aaacgaccgc gcagggcacg atttgcgtta tgcaatcgat tcgacaaaat tgcgagaaga
    13141 gctaggttgg cagcctgagt ttacgaactt ccgtgatggg ttggctgaca cgatcaaatg
    13201 gtacgaagaa catgaagact ggtggaaaaa agaaaaagag gccgttgaag cagcatatgc
    13261 caaaaatgga caataataca gaggaaattt cactgtatta atggaaaaac acatgtgagg
    13321 caggcgctcg cctgtctctt ttttaaaata aaaatcaagg agcggataac catatgtttt
    13381 tattaactgg aggaaatgga caattaggta cagaattgcg ccatttatta gatgaaaaaa
    13441 atctgccata tgtttcaaca gatgcaaaag acttggatat cacagatgct gagaaaacaa
    13501 tggcttatat tacagaatta aaacccgatg ttattttcca ttgcgcagct tacacagcag
    13561 tagataaagc agaagaagaa gcaaaagaat tagatgagaa aatcaatgtc gatggcacaa
    13621 gaaatgtagc acttgcagca aaagctgtga atgcacaatt cgtctatatc agtacagact
    13681 atgttttcga tggaaaaaac aaaaatgtag aatacgaagt agacgaccaa acgaatccac
    13741 taaatgaata tggtcgtacg aaattattag gcgaaaaagc agtagaagag attttagaag
    13801 actattatat catacgaact tcttgggttt tcgggatcta tggacacaat ttcgtcttca
    13861 cgatgcaacg cctagcggaa acccgcgaca aactgactgt agtaaatgac cagtttgggc
    13921 gaccaacttg gacacgtact ttggcagaat ttatggtata tgtcatcgaa gaaaaagcac
    13981 catttggtat ttatcatttg tcgaacgaaa atagctgttc ttggtatgag ttcgcaaaag
    14041 aaatattgaa agatacagat gtagaagttg cacctgttac gtcagaagaa tttccgcaaa
    14101 aagcaacacg tccgcagtat tcagtcatga gcctgaaaaa gacagaagcg ttaggttttg
    14161 tcataccaac ttggcaagaa gcacttgcgc aaatgctgga agctgccaaa aaaatgaata
    14221 agtaatttcc tttttatcaa atagaatttg gagcatgata tggaaaaaca aacaagaagt
    14281 gcacgacgaa aagaaaagcc aaaagcgaat caggcagatt cgaatttggt gcttgacctg
    14341 tttctaaaac tccgctatct tattggcgtt ttagtcatcg tggtcatcgt tacttttaat
    14401 ttaaacggaa gttcacttgg tgtttgggat aaatatgtgt cgcaaagaga cgatgggaaa
    14461 aaaactgatg tgatttttgg acagaatcgg gaagtgcggt cagacgaatg gctggtgcag
    14521 acaccttttt acctctcaca agctgaagag gacttttcgt tggtgaacga ggattattca
    14581 ttaaacggac aaaacatgat cattgcgtat aattctcctg taaaggatat tacggttatc
    14641 ggaaaaccat tcaactgggg attctttttc ctcggaagag atcgaggact ttccttttat
    14701 tgggcgatga aattagtcgt catggtcttg cttggattcg aagtactgat gatattaacg
    14761 aagaggaaaa aagctctatc gctaatcggt gcatttgcgc tgacattttc tccagcagtc
    14821 cagtggtggt tcatgcaaca tgtgggcgat ttgattttct ttactttggg actgatgatt
    14881 gctttttatc attatttcta caatcatgat aaaaaatggc tacgaacgtt gatgatgctt
    14941 ttggtggtta ttttcggtat tgggtttatt ttagtgattt acccagccca tcaagtgatg
    15001 ctggcgtact tgctgatttt ttattttgtt ggcctgctta tttactatag caagaaagtt
    15061 tcatgggatc tgttggatgt agtgttgatt ggaggggcag ttttatttat tggcggagtc
    15121 atggttcatt tctggctaac gtcaaaagac gcattgttag cttctttgaa taccttatat
    15181 ccaggaaaac gggtaagtac tggaggaaag tggacgattg gcgaattttt ttctttcctt
    15241 acaaattgga aaattccttt tgaagatatc aactattcga ataactctga agtggccctg
    15301 ttctatcact tttttccaac tgtattccta gcaagtccat ttgtgttatt tggcaaaaaa
    15361 gatagcgaac aaaagttact gggacgtatt ttgatgattt tttgtctgtt ttctatcttt
    15421 tggattaccg ttgggttgcc aaaatggcta gcagaaatca ctctgctgtc ttatgttcct
    15481 ccattaagag ccatccttac ttttagtttt gcggcttgtt tattatcgat ctggtttatc
    15541 gcttatattt ggagagaaga tgttattcct atttggtata aattcatttt gttggcagta
    15601 aatgcatggt cttatttcta tgcgattacg cattcgaaaa tggataatta tttttcggat
    15661 tttgaaacca tcgcagttgc tgtgttggga acagtgattt tagcttttgc attatttggc
    15721 tggagacgct tgttttacct cgcttttgtc gccttagtta tcgtatctgg ctttttcgtc
    15781 aatccagtcg tagaaggtac aggagcgatt tttgaaaaaa cactggcaaa agaaatccaa
    15841 aaaatcgatc aacaagatcc tggtaaagtt tggttgtctg aagatgaatt atataacttc
    15901 accccaacat tgggagtgaa atccttcaat acagtacgct tttatccaga tatagctgca
    15961 tggaagaaaa tcgatccgaa agaagaatac gagaagtatt ataatcggta tgctcataca
    16021 agagctttta tcgctaagga agatacaaag ttcattttag atcgtccaga tatgttttcg
    16081 gtcacgttga attttgaaga cgcagaaaaa ttagggatcg actatgtgat cagtaaacga
    16141 ccattaactg attacaacca attatatgaa gcgcagttca cgcagctata tggaccggat
    16201 aaagacggtt atatgatttt taaagtagaa tatccggatt atccagatgt accacaaaca
    16261 caaactcagg aaaatcagct agtcgtacag taataggcta gctgagaata atcctgaaat
    16321 attagtagaa aggagagtga agataattca agcaatcgta caaaaatttg tcaacaaaat
    16381 gagtgtcggt ttcttgcttt tgttgctgac gctagtcttt tttgtttgga cagcaggggt
    16441 aggttttcca gcaactttgt ttatatataa caatagttca ttacttatcg cttttagtgt
    16501 ggctattttg ctcattttaa atgtttataa agcaaaaggc gtcgattttc tttatctagg
    16561 tgttgcgctt gcccttttca ttttcttttc ttactttcgg gaattaagaa atgagtcttt
    16621 atttggagac ttactgtttc ctttgattat tttattttgt ttagtaatta aatggatcga
    16681 gtggacaaaa tgggatcgcg gtatttatct gattgtcttt acggtcttcc tcggaatcac
    16741 gttatatcgt gtatttacag agatccaagt accagaagga caaagcatct gggctccagg
    16801 caattcgctt tctgatattt ggatcaatac gaatacaatc ggaagttctt tgatgactct
    16861 tgctttattg atcagtggat ttgccagttc ttttgaacga tggtatgttc gaatcatcgg
    16921 tgggatagca gtcgttgcag cctttttagg tatttgggtc tgccaatcta gaggtgcatt
    16981 agtcgcgttg attgtttttg cgatattgga tcttttacct aaatcgttga tgcgtgtcat
    17041 tcgtgcgcca tttattgcct acacggttac gattctttta gctttgccga tttcttatct
    17101 ggcggctgtc tctgaaaaag tcaatttgtt taccggtcga gaagatattt ggcataaatt
    17161 ctatcagacg ctaggagaaa aatctgaaca agttttacta ggaatgaaaa catttatctt
    17221 ccagcgagga aaccaatttt taggaaacca caatagttat aattctattt tgaatatcta
    17281 tggattgata ggatttggga ttgctgcttt gctgcttatc ctttttattg gtcgcttaac
    17341 gttgaaagca gatttatcca acgggcagat gacttttatc tgggcctttt ttgcggtgat
    17401 gatgcagtca tttatggagg atacattgac ttcataccga tgggttccga ttatttatat
    17461 cctgttggct atggccgttc atcgatatga tgaaccagaa gttacggagg aattctatgt
    17521 tatggaagag gcatatgacg atatgactta tgatgataca tcttatgagg aacaaccaga
    17581 tagcgctcat tcttccagga tccaacgcta tcattgatag gcacaaaata cgagagaggc
    17641 tgtgacaacc gtcgcagcct tttttggttt attgcaattg tctagcatct tctgtaaaat
    17701 agaaacgtta gagaaaatct tgtatcatag aaaattaaga aagaaataag aacgcagctc
    17761 ggtaccaaaa atatggtaaa atggcacttg actgtaattc actgaaaatc gcttggagga
    17821 acacaaatgt ttaaagattt gtatttattt atgaaggaca tttatcagaa cagaaaatta
    17881 ctgctacagt tttcgatcaa tgacttcaaa tcaagatatg caggatcgtt tttaggaatc
    17941 ttatgggcgt ttatcaatcc gctatttact gtattgattt attggctggt atttggtgtt
    18001 ggactgaaag cacaaatgat cgatgcaaaa tacccattta tcgtatattt agttaccggg
    18061 atgattccct ggttcttctt ctcagatgca tttgcatcaa ctacggttgt ttttcgggaa
    18121 tatacttatt tagtaaagaa agtcgtattc aatattcgta tcttgcccac gacgaaaatc
    18181 ctatccaatc tgtacaccca tttattcttc attctgattg gcatagctgt cgcgcttata
    18241 aatggtatat atccttcagc aatgtcttta cagctgattt attatttatt ttgcatgtgt
    18301 gctttcttga caggattgac ttggctgacg gcatcgatcc aaccattttt acctgatatc
    18361 atgcaattaa ttacgatcgt gctgcagttg atcatgtgga cattaccgat attatggagc
    18421 cctaatcagt ttgattcagg tcttgtaagc atattgaaat taaatccgct gtactatgtt
    18481 gttcaaggtt atcgtgagtc atttttaagt gaagcttggt tctgggagca tggaacatat
    18541 actttgtatt tctgggtttt cacgttagta atgttcgtaa tcggctctgc agtgttccgt
    18601 agattgaaac cacatttttc agatgtgctg taaggagaat agctatgaca gaatatgcaa
    18661 ttagactaaa agatatcaca aaatcttata atatgtacgc aaaaccttcg gatcgatttc
    18721 gtgaagccct caatcctttt aagaaatcct atcatgatgt attttatgcg ttgaaaaacg
    18781 tgaatgtaga aataaaaaaa ggtgagatga tcggtttcgt gggagaaaac ggatcgggaa
    18841 aatctacaat gttgaaaatc attacgggag tactgacacc aacatccggc acgatggaaa
    18901 tcgaaggaaa aatctcagct ttgctagaac taggatcagg attcaatcct gagtattctg
    18961 gctatgaaaa tatctattta aatggaatgg ttctaggatt ttcaagagaa gaagtcgatg
    19021 aaatggtcga tgatatcatt gaatttgctg acatcggcga ccatatttat caacctgtaa
    19081 aaacctattc aagtgggatg ttcgttcgtc tagcttttgc tgtagcgatc aatgtgaatc
    19141 ctgatatttt gattgtggat gaagcattgg cagtaggaga tcttgaattt caactaaaat
    19201 gtatggaaaa atttacagaa atcaagaact cgggaaagac gattttattc gtttctcatg
    19261 atattagttc gattcgccgt ttttgtgatc gttcctattg gttgaaaaat ggaaaagttg
    19321 tcgaatatgg tgatacgatg gaagtaacga cgaattacga aaactttttg aagaaaaaat
    19381 cagttaaaac agtagatcga aataaaaacc aagtagaacg cttcgcagct ccagatatcg
    19441 tagacgtgac gaaagccgaa ttgttggata aagataaaaa tccagtggat atgctggaac
    19501 aaggagaaaa actatacgtt aaagtaacct atgaagtaaa agacgataca atcaaaaatc
    19561 cagttttagg aattgctctg cgtacagtcg acaattttta tgtgtgcgga ctcaatactc
    19621 tactagatgg tatcaagatc ccttggaaaa aaggtgagaa tatcttttat ctggagtatg
    19681 aaaagttagg tttgttagct ggtgaatatt attttgacgt tgcggtcttt gaagaaaatg
    19741 caacggttcc tttggtatac aagacaaaat acatgaactt gtttgtcagc ggttcttata
    19801 tcggagaagg catcgtggtc ttagaccata aatgggaaga agggactcat agcaatgaaa
    19861 tatgattttg aaatggacct agatgaacaa agcagtgtgg gaaaaattgc cgcacagatc
    19921 aaaccaggaa gtaaagtttt agagtttggt cctggaaacg gccgattaac gaaacatttg
    19981 atcggagcaa aacaatgtga agtgagcatt gtcgagctag ataaggaatt gttcgatttt
    20041 gtcagcgagt ttgcccaaga tggattttat ggagatatcg aaagttttga atgggcaaac
    20101 tattatgctg gacaaacatt tgattacgtt ttgtttgccg atgttttaga acatttggta
    20161 gatcctggaa aaacgttgaa gaaagttaga gaatttttga atgaagaagg agaaattcta
    20221 attacattcc ctaaccttgc gcataattct gtcatgattg atttgttcaa taatcaattg
    20281 ccatgggctt cttatggttt gctagatgaa acccataatt ctttttatac tcatgatggc
    20341 ttccaaaaag tttttgaaaa agcaggatta tacatcaata ttgaagatta tttgtactta
    20401 gctgtaggtg atacagaatt aaaatcaact tatgaagaat tgccggaagc tgtacgttat
    20461 gatttcaaaa tgcgaccatt tggcgaagtc taccaatact tcttctcatt gatgaaacat
    20521 ccagtagcac aaagttccat tgcgcagccg caaaattcta attatgtgaa agtattagaa
    20581 gtaatccagc aaacgaaaca agatgaaata attcaacaaa taccattcaa taatttcaca
    20641 ggggaaaatg agacactaag tttccatgta tcagaattag cagaacgaat ggtgtttcgc
    20701 ttcgcgcagc aacctagctt tatcgaattc agcgcagaag ctgctggaga aaaactcaca
    20761 tttatcgatt caaatgctgt agtcaaaaca gtaaatgatt gttatttgtt tgatggtaaa
    20821 gatttaccag agttcttttt aacggatatt gcagggaaag aagtgactat ccattgtcac
    20881 tatcgtttta tcggagaatt gacaccaaca atgaaagaat tgctggaaac aatccgtcca
    20941 atggctgaag ttacaaagca gctttctgag aaaaatgatg aattagaaag agaaaatcat
    21001 tatcttattg agaataatac aagattagat cagacgttga aaacaaccat aaatcgctat
    21061 tgcacgttgt tggaaagtga tgaatggaca atcaaacata gattagggcg acgtaagaaa
    21121 gaaacatcga aaaaaatcca agaaaaagag ctttctctat gtattgacga aaaaatctgg
    21181 gatgcagaaa caaagatatt gaaaatcatc gggtggggaa tcgctaattc ggatcgccaa
    21241 ccattgtcct ataagttatc agccgaccaa tcaccatttt ttgaagcaat tcctgtttta
    21301 cgagaagaag tcaatcaagc aaaacagcta gctgaaggag caaaagcagg atttgaactg
    21361 cggatccttt gcgagaagga acgttcattc ttagttgaag cagtggctca aaatggtcaa
    21421 tcatggatca ttgaaatgta aataatgatt aacttataaa gataaggagt aaacgaatcg
    21481 tgcaaaaaaa agaaattgcc gtatttatcg atcaaatcac tcgtgaacgg gccactggcg
    21541 atttgcttat tgtgggctgg gcaattgatg aagtgaccaa agaaatccct acgataaagg
    21601 tagaaaaaga aaatgtgatt gctgaagcaa cacatgtcgt aagattggat atcaatcatt
    21661 tatataatct tgatgttaag acccaaagcg gttttaaggt acgtttatca gggaaaatga
    21721 gaggaaaagc aatcttagac ttccaaacag caagacatca aaatggcata gctgtgaaat
    21781 taaacggtaa atatccttat gatgacggca ttgaatcttc atgggaaaga aaaaaaagat
    21841 tactgaaaaa agggataaat tatgcaagga ctcatggcgt aaaaaaagca atccgccggg
    21901 tcaaactgga attgaaacca ggatcgatcg actatgcaga gtggatcagt cgtcatgaga
    21961 aacctgatct gaaagagcaa aggaaagaag tacaaggatt tgcctaccgc ccattgattt
    22021 ccatacttat gcctgtctat aacgttgaaa tcaaatggct cgaaaaatgc attgattcgg
    22081 tacttgatca aacgtatgat cactgggaac tatgtatcag tgatgatgct tctactgatc
    22141 cagctatccg aaagtgtcta gaatcctatc aagcaaaaga tgatagaatt aaagtcgttt
    22201 tccgacaaga aaatggacac atcagtctgg caactaattc tgcattggaa atggcagaag
    22261 gagagtttat agcgctctta gataatgatg acgaattacc tccatttgcc ttatatgaag
    22321 tggcaaaagt gctaaacgta catccagaac tggatttgat ctacagtgac gaagataaaa
    22381 tcgatgcaga tgggaatcgc tttgacccgc acttcaaagc agactggtct cccgatacat
    22441 tgatgggaaa taattatatc tctcacttag gcgtatatcg gacaagcatt gttaaggaac
    22501 ttggcggttt ccgtaaagga tatgaaggct ctcaagatta tgatttggtt cttcgtgtga
    22561 cagaacaaat tcctgcagaa cacatttacc acattgaccg tgtcttgtat cattggcgga
    22621 cgatcccggg atcaactgca agcaatggag aagctaaaag ctacatctat gattctggag
    22681 tgaaagcatt gacagatgct ctatctagaa gaaatatcaa gggaagcgta catcctggca
    22741 gaatttctgg tttttatgaa atcacttatg atgttttgca agaagacttg gtcagtgtga
    22801 tcattccaac taagaatggc tatgaagatc taaaaacttg tgtggattcg atcatcgaaa
    22861 aaacgtctta tccaaattat gaaatcatta ttgcagataa tggaagtaca gatcctaaaa
    22921 tgcaagaatt atttgcagaa tacaagcatc agctgaaaga ccgatttatc gtcgaattaa
    22981 ttgacattcc attcaattat tcacgtatca acaatctggc agcagaaaaa gcaaacggca
    23041 aatacttttt attcttgaat aacgatacag aagtgattga acctgactgg atgacagcga
    23101 tggtttctta tgcacagttt gatcgaatcg gctgtgtagg agcaaaatta ttttatccgg
    23161 atgatacaac gcagcatgca ggtgtattat tagggatcgg tggcgttgca ggacatgcat
    23221 tgaataacta tgatcgaaca cattgtggtt actttggccg attggtcatt gacgtcaatt
    23281 acttagcagt cactgcagct tgtatgatgg tcaaggcagc tgacttcaat gctgtcaatg
    23341 gatttgatga aatattagaa gtagcattca acgatgttga cttgtgcttg aaagtttatg
    23401 aactgggtcg ttacaatgtc tatgcacatc aagcagaatt gtaccatttc gaatctaaat
    23461 caagaggtta tgaagataca ccagaaaaac aaagacgttt tgctggggaa atcaaaaaaa
    23521 tgcaagataa gtggccttct tatattgctc atgacccatt ttataacgat aatctaacta
    23581 aagaaggaat cggcgatttt tcgttgagac ctgattgatt aaaagaactg tattttcatt
    23641 tttattaatg aaaatacagt tcttttaatt taa
//
LOCUS       DAZKNV010000043        23438 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000043 DAZKNV010000000
VERSION     DAZKNV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.043"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            224..1099
                     /locus_tag="ACG8M1_001898"
     CDS             224..1099
                     /locus_tag="ACG8M1_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0422581.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            1113..1436
                     /locus_tag="ACG8M1_001899"
     CDS             1113..1436
                     /locus_tag="ACG8M1_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422582.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            1433..2185
                     /locus_tag="ACG8M1_001900"
     CDS             1433..2185
                     /locus_tag="ACG8M1_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFQ0422583.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            2175..4346
                     /locus_tag="ACG8M1_001901"
                     /pseudo
     CDS             2175..4346
                     /locus_tag="ACG8M1_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(4458..6629)
                     /gene="copB"
                     /locus_tag="ACG8M1_001902"
     CDS             complement(4458..6629)
                     /gene="copB"
                     /locus_tag="ACG8M1_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFQ0422584.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHVGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(6649..8835)
                     /locus_tag="ACG8M1_001903"
     CDS             complement(6649..8835)
                     /locus_tag="ACG8M1_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0422585.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(8835..9044)
                     /gene="copZ"
                     /locus_tag="ACG8M1_001904"
     CDS             complement(8835..9044)
                     /gene="copZ"
                     /locus_tag="ACG8M1_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFQ0422586.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQFEKICQAINGLGYKAEVI"
     gene            complement(9057..9497)
                     /locus_tag="ACG8M1_001905"
     CDS             complement(9057..9497)
                     /locus_tag="ACG8M1_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFQ0422587.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(9571..10110)
                     /locus_tag="ACG8M1_001906"
     CDS             complement(9571..10110)
                     /locus_tag="ACG8M1_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFQ0422588.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(10725..12191)
                     /locus_tag="ACG8M1_001907"
     CDS             complement(10725..12191)
                     /locus_tag="ACG8M1_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0422589.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(12502..14583)
                     /locus_tag="ACG8M1_001908"
     CDS             complement(12502..14583)
                     /locus_tag="ACG8M1_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0422590.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(15108..15467)
                     /locus_tag="ACG8M1_001909"
     CDS             complement(15108..15467)
                     /locus_tag="ACG8M1_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFQ0422591.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGISLIVNIIWLIISGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(15497..15838)
                     /locus_tag="ACG8M1_001910"
     CDS             complement(15497..15838)
                     /locus_tag="ACG8M1_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422592.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSFFAQF"
     gene            complement(15835..16509)
                     /locus_tag="ACG8M1_001911"
     CDS             complement(15835..16509)
                     /locus_tag="ACG8M1_001911"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0422593.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLIAQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(17439..18737)
                     /gene="asnS"
                     /locus_tag="ACG8M1_001912"
     CDS             complement(17439..18737)
                     /gene="asnS"
                     /locus_tag="ACG8M1_001912"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFQ0422594.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(18777..19967)
                     /locus_tag="ACG8M1_001913"
     CDS             complement(18777..19967)
                     /locus_tag="ACG8M1_001913"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0422595.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(19988..20515)
                     /locus_tag="ACG8M1_001914"
     CDS             complement(19988..20515)
                     /locus_tag="ACG8M1_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFQ0422596.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(20562..23351)
                     /locus_tag="ACG8M1_001915"
     CDS             complement(20562..23351)
                     /locus_tag="ACG8M1_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFQ0422597.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
BASE COUNT         6559 a         5022 c         4141 g         7716 t
ORIGIN      
        1 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
       61 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
      121 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
      181 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
      241 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
      301 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
      361 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
      421 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttggc
      481 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
      541 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
      601 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
      661 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
      721 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
      781 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
      841 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
      901 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
      961 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     1021 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     1081 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     1141 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     1201 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     1261 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     1321 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     1381 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     1441 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     1501 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     1561 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     1621 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     1681 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     1741 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     1801 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     1861 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     1921 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     1981 agcttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     2041 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggcttatct
     2101 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     2161 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     2221 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     2281 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     2341 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     2401 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     2461 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     2521 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     2581 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     2641 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     2701 tccggttgtt gtcgggaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     2761 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     2821 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     2881 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     2941 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     3001 ggaagatcga aaataaaaat cattacaccg gttctggatg gatagaagat caggacgcac
     3061 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     3121 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     3181 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     3241 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     3301 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     3361 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     3421 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     3481 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccgaaagaac
     3541 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     3601 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     3661 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     3721 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     3781 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     3841 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     3901 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     3961 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     4021 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     4081 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     4141 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     4201 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     4261 aaaaaaccta tttagaaata acgcgtataa taagaaaaac ggtatacaaa aaaattctga
     4321 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctggaatgc
     4381 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     4441 acaacctttt ttcattatta tttgattttc aatgtcaaag catttagagc tacaactacc
     4501 gtacttaacg acatcaagac agcaccaact gctggactta atatgatacc aattggcgca
     4561 agaattccgg ctgctagcgg aattgcaaga atattgtaac ctgcccccca ccagaggttc
     4621 tggatcattt tctttcgcgt ttgcttggct agatcaagaa aatgcaaaat atcttttgga
     4681 tcgctgtttg tcaatacgac atccgcagaa tcgattgcga tatctgtccc tgcaccgatt
     4741 gccatcccga ttgaagcacg ggctaaactt ggcgcatcat tgatcccatc acccaccatg
     4801 attacttttt tcccttggtc aaggtatttc tggacaacag cttctttatc atctggtaat
     4861 aaaccgccat aatattcttc gatccctaaa taatctgcta ctgcttgggc agcgttttta
     4921 ttgtcaccag taagcatgac aggagtgatt tttctttctt tcaatgttcg gataaattct
     4981 tttgcttctg tttttactac gtcacctaaa gcaacgattg cagctagatg attttctaaa
     5041 atcaggaagc tgatggtatt tccttgttct tggtaaggtt tcaataatgc ttgttctacg
     5101 tttaatccga gacgctcaac ttctttttca ttaactattt tcacttgttg ttttttgact
     5161 gttgcctcta gcccgactcc tgaaagattt tttagatttt cagcttgata aggcttgatt
     5221 tcatgttctt tcaaataatt cataatgcca acagccaatg gatgattggc attcgcttcc
     5281 aaggctccta gatattgaag gatttcattt ttattgaacg catcatcaag tacttcgaca
     5341 cccgttacag taaattttcc ttctgttagt gttcctgttt tgtccagcat gatcacatct
     5401 agatcattgg cttgctccag tgcattgcgg tttttcaaaa gtaatccgtt tttagctgct
     5461 attgatgtgg agcgagcaac aactaatggg atagctaaac ctagagcatg aggacaggcg
     5521 atgataaaga ctgttaccat acgttctaat gcattaggaa gatctgtcaa gaacaaccag
     5581 gcgatgaatg ccaggatacc cacaattaat gcgacataaa acagccattt tgccactttg
     5641 tcagataatg actctagctt ggatttttct ccttgtgctt ttcgcaccat ttccataacc
     5701 ttcgctagat aaccattttc accagttcca gttacttcga tttcgatcgt tccatcccca
     5761 ttgatagaac cgccaatcac tttgtcattg gcttgttttt tgattcctct tgattcgcca
     5821 gtcacagctg attcgtcaac aattgtttca cctttcaaga ttacaccatc tgttggcatt
     5881 ttatcaccag accggacgat caaacgatca ccttcgttta cttctttcaa tgaaactgtc
     5941 tcttcttttc catctttcgt caagcgtttc actgattctg gcagtaattc tgctagtttt
     6001 tgtaaagcat tgctggcatt cgacacagca ttcatttcaa tccagtgacc tagtagcata
     6061 ataacgatca aagtagccaa ttcccagaag aaatccatga cgtgtgtatg tggattgagc
     6121 agatttgcga taaacgaata gacactataa atatatgcaa ctgtaatccc catcgcgatc
     6181 agtgtcatca tagcaggact tttttgtttc aattccatct tagctccact taaaaatggc
     6241 tgaccgccat agataaatag tatagttgct aagatcaata cgagccaatc agaaccagga
     6301 aacgttactt gaaatggaaa ttccattccc atcattggtg aaaaaagaat gattgggata
     6361 gctaggataa gcgatagcca aaatttttgt ttgaaattcc ccatgtgcat ggaatgatcc
     6421 atgccgacgt gttcgtgatc catgtgcatc gaatggtcca tttgtttgct gtttgctata
     6481 tctccatggt tatgtcccat gtgcatggaa tgatccatct gactatggtc atgtttcatc
     6541 tccatctgtt tttcatgaga ttctgtactt tctttgttta ctacttcttt tttatgctca
     6601 tgttttttct ccatatcgtt cccattcatt tttactccat cccttctctt actttttcat
     6661 gtgtcgattt aagctcaggg agttcaacaa tacactgacg gaactaaacg ccatcgctcc
     6721 tcctgcaatg attggattca aaaagcctag tgcggcaaaa ggaataccaa tcgtattata
     6781 gacaaaagcc cagaaaagat tttgtttgat ttttctcaat gtcaacctag acaactcgat
     6841 tgtttgtgca atggatgcca aactgctatt catcagcgtc acatcggctg tttccatcgc
     6901 aatgtccgtt ccacttccca ttgccatacc gacatcagct aatgctaagg ccggtgcatc
     6961 attgattcca tcgcctgcca taccgacttt tttgccatct ttctgaagtt tttctacgta
     7021 ggctgcttta tcctctggaa gtacttcagc aaagatatgc tttggatcaa taccaacttg
     7081 tttaccaatc gtttcggctg ccagtttgtt gtctcctgtc agcataaaaa catctaatcc
     7141 tttattctgg agctgcttga ttgcttgttt ggcttctagt ttgatttgat cagccacggc
     7201 aatccacccg atcacttgct tttcatcagc taaaaacatg actgtttttc cctgctgttc
     7261 taattctaac gcgtgttctt ggtattcatc aaatgatagg ttcaattcaa ttaatcgttt
     7321 acgtgtaccc gcaaaatagc gtactccatt aatcgtaccg ctgatcccag cacctgggtg
     7381 ggctgtaaaa tcaatcatat cgtatgttgc tgcttcttgc agttttccgt attccacgat
     7441 tgctttacct agtggatgtt cagaagcttg ttctaaagta taaaaaatag ataggacttc
     7501 ttttgaaccg actagatctg taactttggg ctttccttct gtaatcgttc cagttttatc
     7561 caaaacaatg ctgtctaagt gagcagctgc ttctaatgct tctccgcctt taattaaaat
     7621 tccatttcgt gcaccaacac ccgttcctac cataatagct gttggggtcg ctaaacctaa
     7681 tgcacatgga cacgcaatga ctaatacaga gacactatgg atcaatgcga gttgccaatc
     7741 accagtgatc aaacctgtag ctatgagcgt gataaacgcg atgactaata cgatcggaac
     7801 aaaaatccct gagatccgat ctgcgatttt ttggattggg gctttgctcc cttgagcatc
     7861 ttccaccatt tgaatgattt gcgctaatac tgtctgcttg ccgacttgtg tgacttccat
     7921 gtgtagcaga ccattcgtat tgattgtccc gccaaaaagc gtgtcatccg gattcttttc
     7981 tacaggaaga ttttcaccag taagcatact ttcatctatc gcactgcttc ctgaaataat
     8041 tcgaccatct gctggaatct gctcaccagg acggatgact agttgatcac caacgactac
     8101 ttcttcaatc gctaacgttt cttctttccc gtttcttatc acttgggcgg tttttgtttg
     8161 aagagacatc aattgtttga ttgcattacc tgttttcgtt tttgctgtat gttccaaata
     8221 tttgccgagc aaaatcagcg tgatgatcat actgctgctt tcaaaataaa gatcttgggg
     8281 gtgtccacgg aaaaatccgt tgtaaatgct caatgcaaag gcagccgatg ttccaattgc
     8341 taccaataca tccatatttg gtgctttcgt cttgattgca tggtacgcac ctttataaaa
     8401 acgagcaccg acataaaatt ggacaggagc agacagcact aactggacga ttggaaaatg
     8461 aaaaaagtga acaatcgccg catggcttcc taacatcata gcaatcattg acaacatcaa
     8521 cggcaaagtc aaaaccgtac tcaatataag atcgaatagc atttttttca aatacgcttg
     8581 cttttcttct gcaatttttt gtttgtgggc ttcatcgtac aaaattgcac cataaccgat
     8641 gttttctacg ctttggatta atttttcagt ggtcgtccct tcatatttga cacttgcttt
     8701 ttcagtggcc aagttgactg tggcattgac cacaccaggt tgtccgttca gctctttttc
     8761 gatcctagca gaacaatttg cacaagtcat acctgtaatg acgaacgtat ccattttggt
     8821 ttctgctgtt gccatcaaat cacctctgct ttataaccca atccattgat tgcttgacaa
     8881 atcttttcga attgaacttt tgtttcatca aacttgaccg taccgtttgc ttttttcaaa
     8941 tttactttca ctttttgcac gccgtcaagt gcgcttactg tttcttctac tcttgctgca
     9001 caatgattgc agctcatacc ttcgattgaa aattgttgtt tcattttttc ttcctcctat
     9061 tgatgttgtt tacattcaca ttgacctggg atacagttac attcgatcgt atctactggt
     9121 tgcttttgtt ccagttgttt caaaatctca ttgatatctt cttgagtcaa agtggcttct
     9181 tctactagat ccgcaatcgt ctctccaatc ctttttgcac agatatggga aaaaagattt
     9241 tccgtcgcac tgcgaactgt ttccatctcc gagacagctg gatgataaat gaattttttt
     9301 ccttcttgtt ctgtccagat cacttctttt tttaccaaac gtcccagcaa agttttgatc
     9361 gttgctggtt tccaatccat cgaatcagct aagatctgcg tgatttcttg ggctgtcgtc
     9421 tgtccaagtg tccaaataac acgcatgatc tcccactctg aatcactgat ctttactggc
     9481 gttttgactt tttccattta tttcacacct ttcgtttaca aatgtaatca ttagcttatg
     9541 aatacagatt acgcttgtaa acaaaaactg tcaattattt ttgctctcta ttttcaattt
     9601 agttaaaaat tcttgtttct ctcgtcttgt tttaaggatg atcagtttat ttcttgcatt
     9661 agctacttgg atcagctgct gtattttcgg ttcattgttt tcttcaaaat gccagataaa
     9721 agataaaaat tctaagtatt ccctgtttag tttctctgaa aatgattcag gcatatctgg
     9781 ccgagatttt ttgtttatct ttctttttag agaacgccaa actactcggt agatggcgag
     9841 ataacgcggc actttaagcc aaatgatctt atctgcttct ttaatccttt cctctaatgt
     9901 agaagtataa tttccttcaa caatccatga cggattagat accataaacg attgctgttc
     9961 ttgcaaaaac cacttttttg cctgaatact gtagtctgtt gtatgccata aaaggtctag
    10021 cggcagtagc ggaaagtcgg tgatttcttt gatcttcctt gcgagggtcg attttcccga
    10081 cccactttgt ccaatcacga tgatcttcat tcttctccct cacttctctt tggaatttgg
    10141 ttcgatcata ccacttataa cgccgcaaaa aaacaaggga ctgtgacaaa agtcgtgtca
    10201 aagtcccttg tttcgaataa atggtgttca atcagctgac cttcagcatt aactcaaaaa
    10261 acggcaaaat atgaggagct attttttcgt ttgttcctct aatactcagg tcaaatcgct
    10321 gattttacaa cctcttcctt aaacggtgtt ctcctgccaa cacctcggtc acaaggcaca
    10381 atagtcaaca aacatgagaa gttgtttttt gaaattgctc cttgtgactc ggagttaaac
    10441 ggcaggctca ctacctcttt cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc
    10501 ccagcaaaac gaaaaatatg aggggctatt tttgtttggc tgttcttatt acttgatgca
    10561 ggacagcttt ttcacaacct ctgattcacg gtgttccaga agtagcttct gcgaaaaaca
    10621 agccgaaact tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
    10681 gctgaccact tctgtcacaa cctcttgtaa caagtatttc tattttaagg ctgaaccact
    10741 gtttctggtt cagtgatttc tttgtttttg tctcgacgag caattgctgg caagatcata
    10801 cctaataaga tcaagacaat tggtgtgatg atattcgtga ataattggaa ccaccatgct
    10861 ttaggatcag cagtataatc tacttttggc accattccta ggatacatgc aaacgcagtg
    10921 aaggcaaagc accaagcacc aaagataaaa ccgatttttg gatttttaac aaatttatat
    10981 tcagaattga atttcttata agctttattc aacatcatat atgccaagaa cacccatagg
    11041 taacgcattg gcatgacaac tgagttcaag ttcgtcaacc attttactaa ttcattcata
    11101 tctttgatac caaagatcgg caacaaaata atgattccta ctagtatacc tgtcagaaga
    11161 taaccattca ccaatgtacc tttacgatta cgtttacgta gccagtttgg tacaaattct
    11221 ggatccgcat ctgctaacaa gatttttagt ggtgcatcaa ttgaaaaggc taatgcggag
    11281 atttgtccaa tcatgtttgt caatgcgtaa atgatcatca atgagttacc gataccatag
    11341 taattaccta aaatttgaaa agcactgtat gccccatttg ccatcaagtc tttaggaata
    11401 ttatcgctag caaacagcat acccattgcg actgagccta atacagcaca aatccctacc
    11461 attgctgcta agaagatcat ccctttagga aattcctttg caggatttct tgtagagttg
    11521 acataagggg atattttttc cgctcctcca actgcaaata ctagcatcga aacggttgtg
    11581 aaataactga aatcaaatgt tggaatatat gttttcactt gattcatatg tggtgtggca
    11641 aattccatcg ttggattgat gaacggtgcc gttacagcta aaagaataaa taagatcgac
    11701 atgacgaaca tcgctgttcc ggccagtccg ccaatcactt tcaaagtaga aagtcctttt
    11761 gttgataaat ataaaaaggc aagaaatata ataagtgaaa taactgctac catttgtact
    11821 gacatcgtat ttacgatatt tccatttcct tggactgccc aaccgccagc aatcaggatt
    11881 gcttgaggct tttgtgccaa ataaggaata tggacgaccc agtaagtcca agcggcatag
    11941 tatgccagtc gtttattaga tgtcgtattt tcgacccatg aactgacgcc tcctttacta
    12001 tccttgaagg ctgaccctaa ttgtccaacg atcaatgcgt atggaataaa ataaatggcc
    12061 aaaatcaata gccaagaggt gacaactgat actccttgct gagcatagtt attaactaca
    12121 ttccccatgc cccaaaccat gttaaatgca attaacgcaa cagtaaacca gcgtaattgt
    12181 ttgttgttca ttcgttctct cctttatgat aaaaatttgt tatccagatg taatcatatt
    12241 caatttttaa caaacttaca agacagtgtt attttatgtg tgtattcttt tatttaatac
    12301 acatcgtttt ttcatatttt ttccatcaaa aaaataagtt attttctttt atttcattta
    12361 ccttattgaa tttcaagcta ttttgaattt tctgcaaaat taaaaacatt agttatttta
    12421 taatcctatc tattttcttt acatttttca ttaagaaaag gatataaaaa aaagaggacg
    12481 ttcattcgtc ctcttcattg atcaacgttt attttttaca tgcaagcttc gcatggcatt
    12541 caaaacagct aatactgtca ccccaacatc tgcaaatact gcatctccca ttgatgcaaa
    12601 accaaaagca cctaaggcaa gtaccaaaat ttttatccca atagcaaaga caatgttctg
    12661 tttgacgatt ttcaatgttt tctttgctaa atggattgct tctgcaatct tcgatggttg
    12721 atcattcatg atgactacat ctgctgcttc aattgcagca tcgcttccca atccacccat
    12781 tgcgattcct acatctgctc ttgctagcac cggtgcatcg ttgattccat ctccgacaaa
    12841 tgcggtcttt ttattgtttc tttgtaagat ttcctctaac cgctgcactt tatcttctgg
    12901 aagcaattcg ctatatatct tgtccacgcc tacttgcttc ccgatatgat cagcaatttt
    12961 tttcgaatcg cccgtcaaca tgactgtgtt cttcacacca gcctttttta attgaaccaa
    13021 tgcgtctacg gcatcttctt tcaaggtatc tgcaataaca agataaccac tgtaactttg
    13081 atcgatcgct agataaagca atgtaccgat ttcttgactt gaaggaaaag agatttcaaa
    13141 tctttccatc aatttgtgat tacctgctaa tacttgtttg ccatcaactt cagctaagat
    13201 cccttcacct gcaaattctt ggatattagc tgttggtaaa agcggacctg cgtagccttc
    13261 taaaacagat tgagcaatcg gatgtgtaga aaactgttct gcactcgcaa catattgcat
    13321 gaatatcttt ggatcgattt ttgtatcgat cgtctggatc gaaaagtcac ctttcgttaa
    13381 tgtgccggtt ttatcgaata ccactgtctc agtttgtgca agcaactcca agtaatttga
    13441 accttttact aatacaccga ttttacttgc tcctccgata ccgccaaaga aactaagggg
    13501 tacggagatc actaatgcac atggacatga gatcactaaa aatgtcaatg ctcgatagat
    13561 ccattcagaa aacgccgctc cagaaacaac aagtggaggt aaaacagcta ataaaacggc
    13621 caatcctaca acgactggtg tgtaatagcg cgcgaattta gtaatgaaat tttcagctgg
    13681 tgctttttta ctgctggcat tttctactaa ttctaataat ttgctgatag tagaattttc
    13741 ataagatttt tctacttgaa ctaaaaatgg tttattttta ttgataaatc cacttaatac
    13801 tgtttcacca acatatacag atttagggac tgattctcct gtaagtgctg acgtatcgac
    13861 taatgattct ccttcgatga tcgttccatc taacggtaca cgttcaccag gcttcacaag
    13921 tacaaactga ccgatctgca cgtcttcagg gttcacggtc atcaatcctt ccgtcgtctg
    13981 cacgtgagct gtttctggac ggatcgccat caattcgcga atcgattttc ttgaatgact
    14041 gactgccaat ccttggaaat actcgccgat ttgataaaat agcatcactg ctacggcttc
    14101 tggatattca ccgatcaaca tagcgccaat cgtagcaaca gacataagaa aattctcatc
    14161 aaagattttt cctttgacga tattcatcac tgccttcttc actacatcat atcctatcag
    14221 cagataaatc aataaatacc ctatcaagcg aattggttca ttaaaatcaa ataatagcaa
    14281 taaagcgata cctgcaaggg aaaataaaat ccggaacagc gtatttctct ctttttcatt
    14341 tccatgttca gatacttttt ccttatctat ttctgttact ttgacatctg gttctaattc
    14401 cttcactact ttttttattt cttgttcaat cgtagccaaa tgatcttcct ctgcgtcaat
    14461 cgttagtttt ccagaagtga agtttaccgt tgcttccttg actccattga tcttctgaac
    14521 tcctttttcg attttcattg cacagttcgc acaatctaaa ccttctaatc tgtaactttt
    14581 cattttaatg acctcctcgc ctcaacatat gaatatctct tcataactaa ttataaatga
    14641 acggttattc atatgtcaag gtatccgaaa gaaaaaatga aaaacatctg catcggaaaa
    14701 tttcttccat acagatgttt tggcttattc tttctttttc ttttcgatca ttgccactgc
    14761 tcttatccaa cccgcacttg ccttcttgat cttgacagga tagcaactaa gtttgaagcc
    14821 tgttgctggc aatttgtcta aattcattaa tttttcgata ggacaatatc ttttttcaat
    14881 ccctgcaaaa tgtccttccc agatattcga agctccacta agctttcaaa aatatagcaa
    14941 gagttcttta atgaaaatta tttcaacttt ccataaacag taatcccata taaataaaag
    15001 acgtaaaagt cacatgggag aacttataca ggaaaacaca tagagtcagg tgaaatacat
    15061 gtatcccacc tgactctatg cgttttctaa cctttattat tctcttttta tacaatttct
    15121 gcaccgaatg gcatcaacgc caatcgagca agtttgaaag attgcttggc aaaaggtatc
    15181 cctatgatcg tgatacatag aaggatgccg ctgacgacat gtgcgagagc aattggtagg
    15241 cctgaaatga tcagccagat gatattaacg atcaatgata tgccagactg gtgataaatt
    15301 acttctttgc caaaaggcgc aaaagaaagg gaggcgatct taaaacattg cataccgatt
    15361 gggataccta tgatcgtgat acaccaaagt atccccgctg ctaaccagct aagaccaccg
    15421 attagtccgc cgaatataaa ccagatgaca tttcctaaac aactcattat atttctcctt
    15481 ctattactgt ttttgattaa aactgggcaa aaaatgattt tattcttctt tttttagctt
    15541 ccagcatcaa atattctgca aatttttttt ggatttcttc cgtattttct tttgttacta
    15601 atgtgtgttg gattagtttt cctgatggtc gctgatccaa tcgttcttct gactgttgca
    15661 cgtccgcttg cgcaaatccg ataatccgtt tttcttttgt tacagcaacg agcaatagtt
    15721 tattcttatc atttaggtca gctgccgttt ttgcttttac gaatgattct ggatgatcag
    15781 taatcagctg attgatttga ggtaaatctt cttttactgc ccaccttatt tccatcattt
    15841 ttcacttttc tttcgctcat ttttatctcc actaaaaaaa tcgactgcgg caattgcatc
    15901 tatccagctt tgtgcaatga tctcatgtcc accaatcgtt gggtggaccc catcttctct
    15961 tgtatatttc gaaaaaccat aagcaatccc taaagcattg aatataccat ctaaaggaac
    16021 cagcaatgcg ccatattcct tagcaagttt acgaacaatt tggattttag ggtctaagtc
    16081 tttacgccag ccatgacggt cgtcggttat aggaagtaca aacggctcca tcaagatgat
    16141 gttgcagatt tccgctgttt gaagttcatt tagtaatttt cgataaacgg attcaaattg
    16201 ctgagcagat ttctcagttc cgaatatagc ctgatcgcta gtattatgcc aggtatcatt
    16261 gattccgatc aaaatcgata catagtcagg ttgtaaagct aaacaatctt cttgccagcg
    16321 tacttgcaga tctgcaattt tgtctcctcc tatcccacgg ttcatgcatt caaattccat
    16381 cgttggatat tgggcgatta gttttccggc aatcaaaagt ggataacctt tacctagatc
    16441 agttgcttct gctcggtctc ttcctgcgtc tgtaatgcta tcaccgataa ataatatacg
    16501 ttttttcatt tgtcaaaaac tcctttttga ataaaacgat gattttcttc cttatattat
    16561 cccataagcc ctatcaagac gaaagagaaa atatatgtat aaaaaatgac atcagcctag
    16621 tcccttcaaa caattgaatg aacgctcatc aagtgtctag ttttttatgc tatttttttc
    16681 ttaacgtgcc ggattcccct tgattccttc gttgtttggt ccagagagat cgatcatacc
    16741 caagcttccg tcaatcagac cactgatgac gccatcaaaa catatattta taggctcatc
    16801 taagacttct agtaaatgtc cctttactaa tatctcttct agattgcttg ggatagattg
    16861 gtcataactt tatctggtcc gatgatttca agggtgaatt gaacttacat atggattatt
    16921 gcatgctgaa aatacggacc tactccatct tcgaatgtta ctattagttt gttttcaggt
    16981 gctagatgat gctttatttc aacagcagaa gcatcatcaa attagatttc catttgaatt
    17041 accttctttg taaatgtttg attgattgcg atttcgttat agaaccttgt gaatcaaata
    17101 gcaatttctt ttgctttctt ctcttgtctg ctggaaactt cctttatccc gtatttaaaa
    17161 aaaagaactg cgagagttcg cagttctttt ttagaataaa cggtgctctc cggccaactc
    17221 ctcggtcaca agtcacaata gtcatcaaac atgaaaaact gttttttgaa attactcctt
    17281 gtgactcgga gctgaacggc aggcgcacaa cctcttgata taaacggtgt tcaatcagct
    17341 gaccctcgat attagctaaa aaaacggtaa aatatgagaa gctatttttc cgttttgttt
    17401 ctctaatact caggtcaagg cactgatttc acaacctctt atggataaat tcggttcaac
    17461 aaacgtggga atggaatagc ttcacgcaca tggtcgatac cagcaatcca agtgactgtt
    17521 cgttcaaggc ctagaccaaa accagagtgc ggaacagaac cgtatttacg tagatcaaga
    17581 taccatgaat attctttttc atccaaaccg tgattacgga tttgttctag caagaaatca
    17641 tagtctgttg cccgttcgct tccgccaata atttcaccgt aaccttctgg tgcgatcata
    17701 tctgcacaga tcaccacgtc ttctcttgtt ggatgtggtt tcatgtagaa tggcttgatg
    17761 gcttttggat agtttaggat aaagacaggc tgttcgaatg aattcgcaat gaacgtttca
    17821 tgaggtgaac caaagtcttc gccccattcg atgtcatcaa atccattttt cttcagtaat
    17881 tcgattgcat catcgtaagt aatacgaggg aatggcaatt ttgtataagt ttttaagact
    17941 tctttgtctc gtcctagtac atctaatgcg tattcgcaat gatctaaaac attttgtact
    18001 aagaatgcta catattgttc ctgtacttct aaactttctt cttgatgagt gaaagccatt
    18061 tctggttcga tcatccagaa ttcgatcaaa tgacgtcgtg tttttgattt ttcagcacgg
    18121 aaagtcggac cgaatgaaaa gacttttccg aaagccatag cagcagcttc catgtataat
    18181 tggccacttt gagataaata agctttttga tcaaagtaat ttgtttcgaa tagatccgta
    18241 gtgccttctg gtgcagaacc agtcaagatc ggcggatcga ttttgacaaa atgatgttga
    18301 ttaaagaatt catacgttgc acgaatgatt tcatttctga tctgcataat cgcatgttgt
    18361 cttgaagaac gcagccataa atgacgatga tccatcaaga agtctgttcc gtgttctttt
    18421 ggtgtgatcg gataatcgtg gctctcgctt accacttcca catttgtaat tccgatttca
    18481 taaccaaatt ttgaacgact gtcttcacgg atttctccag ttactaacac ggatgtttct
    18541 tggtgtagat ttttagctgt ttggaaaact tcttccggca cttcgctttt tacaactaca
    18601 ccttggaaaa aggctgttcc gtctcttaat tgtaaaaatg cgatttttcc gcttgatcgc
    18661 ttatttgcga cccaagcgcc gattgttact gtttctccca catggttttt cgaatcgatg
    18721 atttgaattt gttccacgta tgactctcct tttatattcc ttgaatttct tcaggattaa
    18781 ttttgacttt tactctcaat aaattgcttg attctgcgta ccgcttcttc taacgtagcg
    18841 cgatcagtag cataactcat gcggacattt tctggtgccc caaagccttc gccagtcaca
    18901 agcgctaccc ctgtttcttc taaaagatct tctacccatt gtgtgacatt ttcatattta
    18961 cacatgcgta gcgtttcttt tacattagga aaaagataaa aagctccttg cggcttttca
    19021 agagaaacac ccggcagttc tgccacaagc ggatataacg tattcaggcg ttcttcaaag
    19081 gcgttccgca tttcttccac tgtatcttgc tcgcctttca atgcttcaac agctgcatat
    19141 tgactgactg ctgtcggatt actggttgac tgggaagcaa cagcgatcat tccattgatg
    19201 atctcagaat tccccaccgc ataaccaatg cgccagcctg tcatcgcata tgttttagac
    19261 acgccgttga tgatgatggt ctgatttttg attgcttctg aaatcgttgc aattggagta
    19321 aactcattgc cattataaac taaacgacca taaatatcat cagcaactat caaaatatca
    19381 ttttttactg cccattcacc gattgcctgc agttcattct tgctataaat cattccagtc
    19441 ggattcgatg gagaattgat gattacggct tttgtttttt ctgaacgtgc ttgttctagc
    19501 tgctcaacag taactttcca gctattggat tcttcccctt tcacaaagac aggaagtcct
    19561 tctgccagtt ttacttgctc accgtaactg acccagtaag gcacaggaat gatgacttca
    19621 tcttgcgggt caaggatcgt ttggaaaagg gtatacaaag caaatttcgc tccgtctgtt
    19681 acgactgttt gtgaaggttc atagacaagt ccatagtttt tcttcagata atcaacgatt
    19741 gcctgtcgaa gctctgggat tcctgctgtt ggtgtataat agctagcttt cccattgcgg
    19801 attgcttcga ttgctgcttc ttggatgttt tctggtgtcg caaaatccgg ttctcccaca
    19861 gtcaaactca gcacatctct gccttttgct tttaatgcct tggcctttgc cgcagctgcc
    19921 aaagtgacag acggttctaa tcgttttgtt ctttttgata actccatccc attcattcct
    19981 ttacctttta aattcccttg attgtcttga cttcatctcc agattcaaag ccaatcaggt
    20041 aataattcag tttcccattt gtttcttttc ctactacttc ccacacaggc tgatcatcat
    20101 acatccctaa agcagctttt tcgatttgga tttcaggatg ggccgcagca attgtctgtt
    20161 ttgcttcgtt ttcagtcagt ccctttgttt gatccaatac ttttactttt tcaccagatt
    20221 taggaatgat aacggcgatt tcttttcctt tatcatttgt acctgtcagt gaaaagtatg
    20281 tcttctttcg agtaaaccaa taaaaatgat cggcttcctc aagatttgca tatttctttg
    20341 cgatttctac tgcttctttc ttcgcctgca ccgccggacg actggaacgc aagtaaaaaa
    20401 tcgagctgat cacgatgacc gctaataaaa atacgatcaa gccaagtaac acgcgattaa
    20461 tcgttttttc ctttgtctgt tttttcttca agggtcgtcg ctcctttatc ttcattcctt
    20521 ttcattatag cagattttaa ttatgaaaaa agacagctcc tctaacttcc ttcttcattt
    20581 ttctttaaga attcatggat gtcctgatag atttcctcca tagctagctc tttgatcggt
    20641 acttttttcg gtaatgcatg gatgatccgt gcaccatatt ttgcagtgac tagtcttcga
    20701 tccaaaataa gcaatacgcc acgatctgtc tccgtcctta tcaagcgacc taatgcttgg
    20761 cgtaacttca aagctgcttt aggtacggat tcctggtaaa aaggattgat cccctctgat
    20821 tctaaataag cgttcctagc tttgaccatc gggcgaagcg gattatcgaa gggtaaacgt
    20881 gtgactacaa cgatctgcaa agcatctcca ggcaaatcta caccttccca aaagctgtca
    20941 gcgccaaaca atacgctttt ttctgacaaa atgaagcgtt tcaaaagctt ctcccggctt
    21001 ccgccaaacc cttgagctag tatttctcgt cctttttcta gcatagacag atgcattttc
    21061 tgatagacct tctgcaaaac atcatgagaa gtgaataaca caagtattgg ccgatcttct
    21121 tgttcgatca gacctgtaag tgctgtctct aaataatcga tatatgcttg attgctgact
    21181 tgatggacgg caggtgcctc ttttggcaca tagatccttg cctgtttctc ataatcataa
    21241 ggagaggcaa tcactttaag aggtgctgct tcaatgccaa gccgcttaga gagatagtgt
    21301 cgattagggc cgatcttcag cgttcctcca atataaagaa tacgatcata tcgaggatac
    21361 caaacagtcg acggcaacat agccgcttga aaatcatgga gatgaaaaat catctgctgc
    21421 gctgtgttcc caggaacgaa ccaatggatc aaatgatctc gccagtcttc cagccattga
    21481 tccatcagca agtactgctt gtctaattga tcaaataagc tatataaact tgctaaatcg
    21541 atccgcatct ggtttgtcca gctttcttgg ataatctcaa aagtcagacg catttgtgac
    21601 tgtagctgct ggatctcctg ataaaaaagc tgcaggtgat caatggctgt cccagattcc
    21661 agtggcagct gatccaacat ctcttttgtc atcatgactt cttctggata ctgtccgtta
    21721 ggttgcttgc cgctcactaa actcattaat ccttctgcca tacaaatctg tgcttcgcat
    21781 agcgcagaaa gttcttctcg ataaatcgat aaccagcgta aggcttcatg ttctttcggt
    21841 aaatagcttt gtattcggtc aaacagctga tttggttctt ctaattgctg gatttgttta
    21901 tggaaatagt taatacttaa tcgtttgtca tttacttttt cagcgatttc cggcaaatga
    21961 tgtacttcat cgatcaacaa aaatggacta gctggaagca atggttcttt tcgctgtgtt
    22021 tcttgtatta aaaacgcatg attgacaatc aaaaaattac tttgcctgat tttcttttgc
    22081 aagaaacgaa caaagtcttg ttcgtaaaat gactgatttc ttgctaaaaa tccaatacct
    22141 ctgtgcgcga tatctgcaaa gaatgaatgg ttcaaatttg ttaaatgtaa ttcatccaaa
    22201 tcaccggtct tcgtttgcgt cagccaaact aagaccgcca tttgatacaa agcatattgt
    22261 ttttgttctg gcggttccac aagtgtgcct ttaaaacgct gtaaatcaat atagtggcga
    22321 tagcttttga taattacagg ttgtatgggc tgatctagca attgattcag caatggaatg
    22381 tctttttcta tgatctgctg ctgcaaaact agcgaaacgg tactgatgac agcgggtttt
    22441 tcaggtgtag ccaaataact caatggcagc agataaccga ttgttttacc cattcctgta
    22501 gctgcttcga tcatcaaatc ttttgattca tcttttgtga aatggtcgta gaccgcattc
    22561 atcagtctgt tctgttcttt tcgatacatc agtgttttac caaacatttt ttcttttgct
    22621 tgtttttttc ttggatatgt ccgctcacca taatggacgg atgtgaatag ttccacttct
    22681 tttttctgca aagctagccc atcgacgatt tctaatgagg gatcaagtgg ctctggtttt
    22741 tctttcattt cttcaatcac atgataaatg aaacgactcg tatccatacc tgtgtgtcta
    22801 cttaatcgcg caatctgctc taacgtgatg attggcaatt ttctcatccg ttcttcgatc
    22861 agcaaaagaa gttgacctgt cacttcggca tcactatctg cctgatgagg attctcatga
    22921 ataaatccaa ggctttctga caaatcagct aagcgaaagc ttggttccgt cggcaagaaa
    22981 atttgtgcaa gttctactgt atcgatgcct ggtatcttca aactaggaag tccgcatcgc
    23041 atgagttcat ggttcaaaaa attataatca aaataaatat tatgcgcgac aaatatggtg
    23101 tctgccaaaa gattgtaaat cgtttgggcg acatcttcga aataaggcgc tttttggacg
    23161 cgttgattcg tgatccctgt taaatgctgg atttgttttg aaatcttccg ccctggatga
    23221 atatcgatcg aaaaacgtga agtgatccga cctgattcaa tcatgacgca gccaaattgg
    23281 atgatccgat cttcttttgg attcgtccca gtcgtttcga tatcaacgac tgcataagtt
    23341 cttggtttca aaatatcttc ctcttctcct gcctctaatg ttcttttgaa attatactac
    23401 aaagtgcaga aaaatactct catcgctttt taaagaaa
//
LOCUS       DAZKNV010000044        22172 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000044 DAZKNV010000000
VERSION     DAZKNV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.044"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            242..2077
                     /gene="tdc"
                     /locus_tag="ACG8M1_001916"
     CDS             242..2077
                     /gene="tdc"
                     /locus_tag="ACG8M1_001916"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFQ0422598.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2382..3860
                     /locus_tag="ACG8M1_001917"
     CDS             2382..3860
                     /locus_tag="ACG8M1_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0422599.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3826..5157
                     /locus_tag="ACG8M1_001918"
     CDS             3826..5157
                     /locus_tag="ACG8M1_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0422600.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5271..7823
                     /locus_tag="ACG8M1_001919"
     CDS             5271..7823
                     /locus_tag="ACG8M1_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFQ0422601.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7830..9269)
                     /locus_tag="ACG8M1_001920"
     CDS             complement(7830..9269)
                     /locus_tag="ACG8M1_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422602.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9244..9426
                     /locus_tag="ACG8M1_001921"
     CDS             9244..9426
                     /locus_tag="ACG8M1_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422603.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            9615..9977
                     /locus_tag="ACG8M1_001922"
     CDS             9615..9977
                     /locus_tag="ACG8M1_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFQ0422604.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10164..11021)
                     /locus_tag="ACG8M1_001923"
     CDS             complement(10164..11021)
                     /locus_tag="ACG8M1_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0422605.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11141..12052
                     /locus_tag="ACG8M1_001924"
     CDS             11141..12052
                     /locus_tag="ACG8M1_001924"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFQ0422606.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12059..13705
                     /gene="mdcA"
                     /locus_tag="ACG8M1_001925"
     CDS             12059..13705
                     /gene="mdcA"
                     /locus_tag="ACG8M1_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFQ0422607.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            13807..14106
                     /locus_tag="ACG8M1_001926"
     CDS             13807..14106
                     /locus_tag="ACG8M1_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFQ0422608.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14096..15772
                     /gene="mdcD"
                     /locus_tag="ACG8M1_001927"
     CDS             14096..15772
                     /gene="mdcD"
                     /locus_tag="ACG8M1_001927"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFQ0422609.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15776..16369
                     /locus_tag="ACG8M1_001928"
     CDS             15776..16369
                     /locus_tag="ACG8M1_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFQ0422610.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16393..17469
                     /locus_tag="ACG8M1_001929"
     CDS             16393..17469
                     /locus_tag="ACG8M1_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0422611.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17494..18363
                     /gene="mdcB"
                     /locus_tag="ACG8M1_001930"
     CDS             17494..18363
                     /gene="mdcB"
                     /locus_tag="ACG8M1_001930"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFQ0422612.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18474..19238
                     /locus_tag="ACG8M1_001931"
     CDS             18474..19238
                     /locus_tag="ACG8M1_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFQ0422613.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19727..21820
                     /locus_tag="ACG8M1_001932"
     CDS             19727..21820
                     /locus_tag="ACG8M1_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0422614.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21845..22147
                     /locus_tag="ACG8M1_001933"
     CDS             21845..22147
                     /locus_tag="ACG8M1_001933"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0422615.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7177 a         3787 c         4724 g         6484 t
ORIGIN      
        1 tttgtttgtt cgcttttttt aggttatcta ttttagaaga ctgatttatt gaaaaattgt
       61 tcgctttttt gcgttgaatt atcagaaaaa tccgacttta tttatttttg tttgtaaaaa
      121 tctacgtgga tttgatgtta taaaaaaaaa attctcattt ttggcgctat agtgaagagg
      181 tgttacagat aaacacatgt atctgcaaga cattgaccaa caaaatatgg agggaagaaa
      241 aatgaaagat atggatatca aggccgtctt tataggcgac aaagctgaaa atggaccagt
      301 ttataaaatg ttgttgaaca agatggtaga tgaacatctt ggatggagag aaaattatat
      361 tccttcagat atgcctgcaa ttagcgaagg agataagctc actccagatt atctagccac
      421 ccgcgaccat atgatagagg tcttggatga agtcagtcag cgattacgcg caggatcgat
      481 cccatggcat tcagcaggcc gttactgggg acaaatgaat gctgaaacat tgatgcctgc
      541 tttattagct tacaactatg cgatgctgtg gaacccaaat aatgttgcat tggaatcttc
      601 tatggcaact tcgcaaatgg aagcagaagt aggacaggat tttgcttcat tattcaatat
      661 gacagacgga tggggacaca ttgcagcaga tggttctatt gctaatcttg aaggattatg
      721 gtacgcccgt tgcatcaaat cgattccttt agctgtcaag gaagtgctgc ctgaaaaagt
      781 gaaaaaaatg tctgagtggg aacttttgaa tttatctgtt gaagaaattt tggaaatgac
      841 cgaaagcttt acggacgaag aaatggatga ggtcaaagca gcttcttccc gtagcggaaa
      901 aaatatccaa agattaggga aatggctggt ccctcaaaca aaacactatt cttggatgaa
      961 ggcgttagat atttgcggag tcggcttaga tcagatggtt gctatcccag ttcaagagga
     1021 ttatcgaatg gatattaatg ctttggaaaa aacaattcgt gaattagctg gacaaaaaat
     1081 cccaattcta ggtgtggttg ctgtcgtagg aacgacagaa gaaggtcaag tagacagtgt
     1141 agataaaatc gtccaattaa gagaaaggtt aaaagatgaa gggatctatt tctatttaca
     1201 tgttgatgcc gcatatggcg gctatgcgcg ttcactgttt ctaaacgaag caggagaatt
     1261 tgtgccgtat gcttccttag ctgaattctt tgaagaacat catgttttcc accactgcgt
     1321 aacgattgac aaagaggtat atgaagggtt cagagctatt tcagaagcgg attctgtcac
     1381 gatagatcct cataagatgg gctatgtccc ttatgctgct ggaggaatcg taatcaaaca
     1441 taaaaatatg agaaatatca tttcttattt cgcgccatat gtgtttgaaa aatcagtaaa
     1501 ggctccagat atgttaggag cttatatttt ggaaggatca aaagctggag caaccgccgc
     1561 cgcagtctgg acagcacatc gtgtattgcc attgaatgtg accggatatg gtcaattgat
     1621 tggggcttca atcgaggcag ctcaaagatt cagagaattt ctcgatcatc tgacttttac
     1681 tgttaaagga aaaacaatcg aagtctatcc attgaatcat cctgatttta atatggtcaa
     1741 ttgggtattc aaagaacaag gctgtacaga tttgaacgct atcaatgaat taaatgaaaa
     1801 aatgttcgat cggtcttctt atatggatgg cgatgtttat ggtgaacggt ttattacttc
     1861 tcatactaca tttacacaag aagattacgg tgattctccg attcgttttg ttgaaagaat
     1921 gggtctaacg aaagaagaat ggaaaaaaga acagaaaatc actctgctac gtgcggctat
     1981 catgactcct tatttgaatg atgatcgaat tttcaatttt tatacaaaaa aaatcgccaa
     2041 agcaatggaa aagaaactaa acgaaatcat ccaatagaac tgatttttgt gtgaaagaat
     2101 aacaagagac atatggagaa cagacaatta tttgcttcat caaaacaatt gtatttcccc
     2161 ctgtttttca tatattcctc gccaagatat tcttttttat aaaacgttct ataagttgga
     2221 tcgttcgttt catgtatcaa acccagttca ctaagatcgt tcaatggatg tttcggtgat
     2281 actgggtttt gtactgaatc gatgaaacct tgtcatttct gttcttgaac aaaaataaaa
     2341 gaaaacaaaa acatatgtcg ctattgaaag aaggaataaa gatgaaagat actggttcat
     2401 caaagcaaat cacgaccatg acctttatcg gaatgacctg cgcccttgta gcaagtgtac
     2461 gaaatattcc agatgtagca gcaacgagct ggacgatgat tttttacatg ctggttgcag
     2521 tattattgta cgcttttcca atctcattga tctctggtga atttgctgga atgtttcccc
     2581 aaaaaggtgg tccagaactt tgggtatcga atgctctagg aaaaaaatgg gggttcgttg
     2641 tctcatggct gttatgggtc caaatgtttc ctgggatggt gatggtcgct tcagcactcg
     2701 ctccgttgtt tggtaatatt atcgataatg tgccgcttgg tttgaacagc aaatttacat
     2761 tagttgtcat tttagtcgtt tattggatca tcactttttt gaatttgaaa tttgatatgg
     2821 caaaaatcgg cggaaaagtc ggtgtttggt taggattgta cgtgcctttg acgatgatgc
     2881 tcttattagg gtttgctgcg tggatcaaag ttgggatcgt accaaccgga acattaggca
     2941 gtttttcatg ggacaaatta ataccagata ctacgactgc atcctcattt gtttattttg
     3001 cgccgatcat gtttattttt actggtatcg aaatgtcctc tgtgtatatc actcgattgg
     3061 aaaatccagt taaaacgtat attcgcggag tatttgccgc gttaattttt atatttttcg
     3121 tcaatatttt gaatgcttta gttgtagcaa atgtcgtacc aaaaggacaa atggaattga
     3181 ataatatcgc gcaatctatt tcgatttatt gccaaattct tggtttgcca catcttattg
     3241 tgaatctgtt tagtttactt gtcttcattg gtgtagcagt ccaattatct gcttgggcct
     3301 caggaccagc aaagacagtg acagaaagtg ctagaaaagg tgcgtatcca ccaaaattca
     3361 atttttggaa gacgaatcaa tttgacgtat ccaaatccgt tattttgact cagtctgtca
     3421 ttatctcaat ctttgcactt ttttatttgc tgattcctgg cgtcaatcaa gcatttttga
     3481 tgctcgtaaa ttcaactact gttatctact gtatcgtcta tgtcatcatg gggatcgcag
     3541 ttttgagatt gcgttataca catgcaaagt tgaatcgacc atttagaatt ggaaaaaaag
     3601 agaaaaagag caatcttgga gtttggactg tcgttattgt tttatttgcg gcaatcggat
     3661 tttctgtcgg actgacgatg aaagctggaa catggatcaa tctaattgca gtcacagcca
     3721 tcagtgtcat tttgtttgta gtaccactct gtattgaaaa aataaagaaa ccttcttggg
     3781 aacaggaagt cgccatgctg cttgaaaaag aaaaaggtga acttgatgga aaaaccggca
     3841 atgaaacgga ctctaactaa tcgaaatatc cagttaatcg cattaggtgg cgcaattgga
     3901 acaggattat ttttaggttc agcaaaggca attgcatcag cagggccagc tgttattctc
     3961 gtttatttga tatgcggttt ggctatttat ggtttgatgc gggccatggg tgatttattt
     4021 ttagcaaata gtacatttaa ctctatcagt gatttcgttg actattattt aggcaaaaag
     4081 tgggcatttt ttgtcaattg gacttattgg ctttgctggc ttggagctgg acttgcggaa
     4141 ttaacagcaa taggattgta tatccatttc tggtttgtac atgtaccagc tttgataagc
     4201 ggaggtagcg cactaatgat cttaatggca gtcaaccttg ttgcagtcaa gtggtttggt
     4261 gaattggaat cttttttctc aatcatcaag atcttgggga ttttcctttt tatcttattg
     4321 ggtataggat tgagtgtctc agattttcat acccagtcta tcggaatcaa agaaaatttt
     4381 ggacagatcg atgaattact accgtttggc tttgctggaa tggtagtctc atttcctatg
     4441 gttttattca gttttgctgg aattgaaatg atcggcttaa ccgttggcga gacaagtgat
     4501 ccgcaaaaga atttgaaaaa agcaatcaac tgtctgcctt ggcgtattct ctttttctat
     4561 ataggaacga ttttgtcgat tttatttgtt gttccatggc attgtttaga tttaaaagaa
     4621 agtcctttag tgactatgct gcaagtgatc cattgccaag gcggagcagc aattgtcaat
     4681 ctaatgattt tggttgcttc tttgtcctca gcaaatagtg cagtctacag tactagcagg
     4741 attttatatc aaacagcaaa agaaaaaagt ttgccccatt ggttttgtgc gctttctaag
     4801 aaaggcgtac ctttacacgg tattttaatt acaggaatgt tattttttgc cggtctttgt
     4861 ctacattttt ttgtagctga tagtcgattg ttttttcagc ttttggcagg catgacaacg
     4921 agttgttttc tatttgtgtg gtcttcgatc ttgtgtgcac atgttcaatt tattaaagaa
     4981 aagaaacgga acactacaca aagatataaa gatcttgctt tgttggtgtt ttttacttca
     5041 attgctttca gcttgttatt cgaaagcacg acacgcttta ttcctttttt attggttatc
     5101 tggtttgtat tcttaaattt tgtatataaa agaataagca atagaaatat cagttaggcc
     5161 cagatacatt ttgcaaaacg aattatttca gacccccctg aaataatcga tacgcctgaa
     5221 aaaacttccc tgcgtataat aacagtatca attaaacagg aggggatagg atgaactggt
     5281 acagattgac ggtagaagat gtattgaaaa actatcaaac atcaacagaa ggcttgtcgc
     5341 aagaagaacg acagaaacgc ctgactgatc aaggatataa tgaaataaaa gcaaggcagc
     5401 agacaaaacg atggaaaaaa atagcaaagc attttactga tctgctgatg atcgtgttga
     5461 tcattgcctc ttttttgaaa tttgcttcta gtgaatatat tgaaggaagt attattttat
     5521 tcgtagtgat cgtcaatgga ctcgttagtt actggcaaga aagaaaagcg gaagaatcat
     5581 tgaatggttt gaagcagctg atgggacaag aagcgatagt actatcaaac gggatgcaag
     5641 aaaaaatccc tgcgaaagaa ctggtaaaag gagatgtcat tgtcttacgt gccggagatg
     5701 tcgttccagc agatatccga ttaatcgaag cacatgattt attagtggaa gaatcgattt
     5761 tgacgggaga atcagaagca tctgaaaaaa gtcatgccgt tttgacagaa gaagaatcga
     5821 tcggcgacca gaaaaatatg ggtttttcag gaacgcttgt acaatctggt tctgcagtcg
     5881 gtgtcgttgt agaaacagga aacacgacag aaatcggtaa aatcaatcaa gcattgcaat
     5941 cggtcgaaca acaaacgacg cctctgatta aaaaaatcaa ccgattaaac aaacaaattt
     6001 ttcaaggcat tctttgtttg agcctattct tagttatttt tacgacattt cgatatggta
     6061 tggattggca tatccttctt tcggctacga ttgctttggt ggtgtcaatg gtacccgaag
     6121 gattgccagc tgttttgacc atgattctat ccgttggagt acatgaaatg gcaaaagaaa
     6181 aggcgatcat caaaggactt ccttcggtag aaacattagg ttctatgaca gtgatctgtt
     6241 cagataagac aggaacattg acaaaaaatg aaatgacagt tgtggatgta gctgcaaaag
     6301 aagaagcctg cgtgttgtcc attatgaaaa actgtcagga attaaaaaca aaagaagaac
     6361 agaaaacaga aaatttaagt ggcaatccga cagaagttgc gctgattcga cacacagaaa
     6421 cagccaatct acctttgaaa aaaatagaag caaagattcc gttcagttct gaatacaaat
     6481 atatggcaac gatgcatgcg gaggaaaaag gagcggtgat ttacgtcaaa ggtgcaccag
     6541 aagtattatt tgctaaatca actctttctt ctgcagaaca agaagcatgg agtcagacag
     6601 ctgcagaatt tgcgagaaaa ggtcagcgtg ttttaggatt tgcttataaa aaagtagatt
     6661 cgaaacagga actcacgcat gagactttaa cccaattaac ttttgcaggg atcgccggat
     6721 tgatcgatcc gccaaaagaa agtgcagtca aagctgtaaa ggaatgccaa caagcaggga
     6781 tctcagtgaa aatgattaca ggggatcaca aagacacagc aaaagcgatt gcggaacaaa
     6841 ttggcttaaa acatactgcc aaagttttag aagggatcga tttggatctt atgtctgatg
     6901 aagagttgat tcagcaagtg ccaatagtcg atgtctttgc tcgaacgaca ccagaacata
     6961 aactgcgaat tgttaaagct ttgcagaaaa atggagaaat cgtcggaatg accggagacg
     7021 gcgtaaatga tgcacctgct ttgaaaagat ccgatgtagg aattgctatg ggaatcaaag
     7081 gtagtgaagt aagcaaacag gcagctgata tggttttagg agatgataat ttccatacga
     7141 ttgcaaaagc cgtaaaagag ggccggcgga ttttggataa tttgcaaaaa accatcaatt
     7201 tcttcttgcc aactgcatta gctcaaggat tgatcttgat ttgggcactt atgctgaatc
     7261 gcccgctacc tttgtcccca gtacagattt tatgggtcaa tatggtaacg acaatcactt
     7321 tatcttatgc actagggttc gagtcgccag atccagaaat catgaagcgc ccaccaagag
     7381 atccaaagca aggaatccta tctggttatc atttgtttcg gatcatctat gtctccctac
     7441 tgatcatggt tcctgcctat ttattggcta tgcagtttga agggcaaagc ttacagcaaa
     7501 ccattcttct gcaaaatatc gtcttagctc aagctgttta catgatcaat tgcagagagt
     7561 tgtccaagcc gtcattgaac caaggtcttt tgcaaaacaa agcgcttttt ctttcattag
     7621 gtatccttgc tttattgcaa gggatggtta tttttctacc agtcggccag cagctgatcg
     7681 gtacagtaag tttaacgatg acacaacagt tattgattgg agcaaatgtg attcttctat
     7741 tcttagttgt agaaatagaa aaagggatca tgaacaaact gtttcgcaaa aaagaaaaaa
     7801 cagctagaga atacagtcgc tagccgttac tataaaaaag ttttgaaagt gagttcagtc
     7861 aaacgattga gctcattttt cgttggaata gaagaaatgt atacaatagg gatatctaga
     7921 gaatctagag ggaaattgga aatcaagata tctgtttttt caaaagaaat agtggaaaga
     7981 tcggttagtt cgataggtaa gaagcagaca cgttttccta agtaatcttt taattcctgc
     8041 tgcaagaacg ccttccatga aggttctcct tggaaaataa aatagacatt gaacaaattc
     8101 ggtttgatag aaaaaatcgt ttgttggatc agtagagaca agagttggag aaagtaattt
     8161 ggttcattga tttctatttc tttttttaga tcgttcagta aattctcttt ctgttgatac
     8221 aagtgtgcat attgctgatc atatgtttct aaaaaacgat ggtattgacg gtccaatgct
     8281 tcaatcaata tcggcgattc atgatatttt aatatgagga gagccaagtt atcagtcaga
     8341 gatgtttttt ttagttgatc aagagacagc tctgaagcta gttcctctac aaacgtttcg
     8401 aggacctcta aaaatggaga atgatgcagg cagcgagcgg tttcttgtcc atagttattg
     8461 ttgtaattcc aactttccag aaagcagaaa gaagcaaaag aaagctcagt gtctttaaga
     8521 taaatacctt ccgttaaata caattttttc aatgcagagt catacaggga ggagagtgtg
     8581 ctgttggtat ggatagaaga atctaatcgg caattcgctt ttatacggat cgtattgata
     8641 aagaaccaac atgttccgaa aatctcttct gtttcaaccg ctagttcagt ttgactgagg
     8701 tttcttaaaa attgaaaata atgggattca tggatcgaat aatcctcgaa aaaatagttg
     8761 ttatgagtga aaggaatcag caatcgatga taaaaagtac gaatcgcacg ctcttttcca
     8821 agaatacaag ctgtatattt cgtcaaatcg atctgcaagt cgtaacttgc taaacgctga
     8881 ttgattttag tcacatgtct tttcaatgtc ccataagaaa gcccatggtc ggctagaaaa
     8941 tcagggacag caactttttt tgtaaaaagc agatttttca gcagttcgac actgactgat
     9001 tgtttgaaaa aaatctccca aaggtcattt gttaataaat tttgctggtt ttgcaaactg
     9061 attcctgctt gatcgctgat gatgtcccag ccttcgggca gctgagagcg aatagattga
     9121 aggtcagaaa aaatcgttcg ttcggttgtc cctatgattt cagctaattc atttacggtt
     9181 atctttgtat gattcagcaa ttgttctact aaagaaacat gacgtcgaat atctttttcg
     9241 gtaatgattt ttttcattag tgaatacatc aatcagactc ccttctattc taagaatacg
     9301 gagaaaataa acggtggtca agtttcaact gatttttcaa tcattgttta tttttctgga
     9361 gcatttactg atgataagaa tttcatcatg aacttgaaaa atgataccac taaaatcaaa
     9421 aaataggtgg gcaaacaata ataaacattt taatagtaga tggtagcaag accaacacag
     9481 gcggattgaa catttaagag ttgataaaaa agaaaaatat cgaagtattt gattagcaac
     9541 tacttgtatt catttttcta ttcttacgtg gtatctttga ataaagcgaa tcaataagaa
     9601 agagatggaa gcagatgcta acgaaaaaag aactaatcga tcacatcaat gaaacataca
     9661 atttgtctcc agaatatatt tttaaaaaat ttcctgatta ttgcgtattc agacatcaaa
     9721 aaagcaaaaa atggtttggg gtcctgatgt ctgttccaga agaaaaaatc tatgatgatg
     9781 caagtgacca taggatcatc aatattcttg atttgaaggt cgatcctgaa cttggcggaa
     9841 ttttgcgagg aaaagagggg tattttccag cctatcacat gaataaagaa cattggatct
     9901 ctattgatct acgtaaaata gaaaagctag atgaactagc agatttgatt gatggaagtt
     9961 ttaaatcaac gcaatgaatg tctaggacaa tagagaagag gttgtgacag aaatgtttag
    10021 cttcaagaaa taagaaggaa tttacgaaaa ttgcttctca aatttttggg aaatttcggc
    10081 ttattttcta agaaattact tctggaacac cgtttgttcg aaaaaagagc tgcgacaaga
    10141 attttgtccc agctcttttt tttttatttt cctaaataaa attcccgcat cgtttttgca
    10201 atcattttga tcaaaggatg atcttctgtg aagctagaag ataaataaat tgttcgtgtc
    10261 aagggcaaat ctttgatttc ccgcaagacg aaaggatcat ttttatcgta agaccaagaa
    10321 acttttggga aaaagctaac agctaatcct tgcttgacaa tagaacgtaa tgtcgcagga
    10381 tcatctgtcg tcgaactgat cgtcaattcg atacttttcg cttcaagtgc tgcatccagt
    10441 gtatgacgga aggcgttgct ctttgacagc atcaagatgg gggtgcgttg gatatcttct
    10501 aattgcagat gttctttttt agcaagagga tgtttcttag gaatggcgac ataaacaggt
    10561 tctttcatga taggaatatt ggtcatgcca ggcttcatct ccgaagtgat gtacagtaca
    10621 ggatcggtaa tatcatctgg taaatgatgt tgcatgatcg ttaattggat atcaggatgc
    10681 ttttccataa aaattcggac caagttcgga atagaaacag aggctacctc taaatacaat
    10741 atgacggaag taacgatctt ctcattgacc gaagacaata atttgattcc ttcttctaat
    10801 gtgtctaatg tcttgactgc atatggataa aattcttctg cataaacggt cgtctcaatg
    10861 tttctgccgc tatggtaaaa caaagggaca cctaattcgt tttccaaatg tttgatcgca
    10921 cggctcaagg caggttgaga aataaataat tctttggctg cttgggtaac attttttgtt
    10981 tcgaatactt ttttaaaata ctgcagatga agcaatttca taattatcca tcccatccat
    11041 acctttttgt tatggttttt tctttttttg gcatttttta ttatagcaga aattgactaa
    11101 gatagcagtg gaaaaagtaa gtgctgagga ggcgaggctc atgagtacag gtttcttatt
    11161 tcctggacaa ggcagtcaga agttagggat gttagcggat atccctgaaa tgtacatgga
    11221 acgtttagaa aatgtgacgg ggtatcggtt agttgataaa gaagaaaact atcaagatac
    11281 ggtttttatc cagctagcat tactgacaaa agcagtattt tatttagatg aaatggaaaa
    11341 aaacggtatt cagcctgata ttgcagcagg acattcgatt ggtgcttttt gtgcagctgt
    11401 tgcttgtcga tctttgagat ttgagaatgc agcggaacta gtctatcacc gcgcagtctt
    11461 aatgaaagaa gcttatccaa gcggttatgc aatgggcgta gtagtaggtg tgacgagaag
    11521 cgaagctgag gaaattgtag caaaaacatt tgatcctgac catccagttt atctgtcaaa
    11581 tgaaaattgt ccgatgcaac atacgttatc tgggagtatc gaaggtttat ccgttacgtt
    11641 ggcagaagcc aaacggcacc aagcgcaaac agcgaagctg ctgaaagtcc ctgtgccatc
    11701 tcactgtctc ttgatgaatg atacggtcaa gaaattcaag ccgtatatgc agtctgtcca
    11761 tctatctgat gctagatgtt tgtatataaa aaatacggat ggaagagcca ctcaggacgc
    11821 agaagagatt cgtaaagatt tgttggaaaa cctagctttc cctgtgcagt ggaaccaaat
    11881 gatggacttg gcaaaagaat taggaatgga tctgacgatt gaatttcccc ccggcaatac
    11941 tttgacaaag ctgattcata caaaatttgg tgtagataaa gggatccgta cgatcaatct
    12001 agaccaacat ggtattgatg acgccacgtt tctatatcaa aaatggagat gactaattat
    12061 ggaaaaacca aaccgcaact gggcttctaa acgcgaaaaa aaagcgcagc gattggaaaa
    12121 aatcagcaac ttgctcaatg gcaagtatgt agaaactgaa aaaatcgtag aagtaatgga
    12181 aaaactgatt gctcccggcg acaaagttgt attagaaggc gacaatcaaa aacaagcaag
    12241 ttttctttca gaaagtcttg aaaaagtaga tgcagaaaaa gtgaatgatc tgcatttgat
    12301 catgtctagt atctcacgac cagaacattt gaatattttt gaaaaaggaa tcgcaagcaa
    12361 gatcgatttc tcttatgctg gtgcacaaag cttgcgtgtc gcccaaatga ttgaagacgg
    12421 cacaatgaaa ttaggtgata tccatactta tttggaactt tatggacgct tattcatcga
    12481 tttgattcca aatgttgttt tagtagctgc agataaagca gataaagacg gcaacttgta
    12541 cacaggtttc aatacggaag aaacaccaac aatcatcgaa gctgcagctt tcaaagatgg
    12601 tatcgtgatc gttcaagtta acgaagttgt cgattcttta ccacgtgtag atatccctgg
    12661 tgactgggta gacgttgtcg tgaaagcaga taaaccttat caattagaag ctttattcac
    12721 acgagatcct caaaacatca cagaattgca aattctaatg gcaatgatgg caatcaaagg
    12781 aatctacgca gaacacggcg tacaatcttt gaatcacggt attggattca atacagcagc
    12841 tatcgaattg ttactgccaa cttatggtga atcactaggg ttaaaaggga aaatcgcgaa
    12901 gaactgggta ttgaacccac atccaacgat gattccagcc atcgaatcag gttgggttga
    12961 aagcatccat agttttggtg gcgaagttgg tatggaaaaa tatattgctg ctcgcccaga
    13021 tgtctttttt gtcggtaaag acggcacgat gcgcagtaac cgaacattat cacaagctgc
    13081 aggacaatat gccatcgata tgtttatcgg ttcaaccttg caattagatt acgaaggaaa
    13141 ctcttctacc gtaacaaaag gacgtttatc tggttttggc ggtgcgccta acatgggaca
    13201 taatcctggc ggtcgtcgtc attctacacc agcatggcaa tcacttcgcg acaatgatga
    13261 tccattaggg aaaggccaaa aattagttgt tcaaatggtt gaaacatatg gttcaaataa
    13321 aaaaccagtc tttgtcgaag aattagatgc actagctgtt caaaaacaag caggcttagc
    13381 caatgcacca gtgatgattt atagcgaaga tactacacat atcgtgacag aagaaggaat
    13441 tgcttatttg tacaaagcaa aaacaaaaga agaacgacaa gcagcaattg cagcaattgg
    13501 cggtgttaca cctcttggaa tgactagcac gaaagaatca ctagatagct tgcgtgcagc
    13561 cggcatcgtg aaattaccag aagatctagg catcaaacgt agtgaagcga aacgttcatt
    13621 attagctgca caaaccatcg atgatttgat cgaatggtca gatggcctgt atgaaccacc
    13681 aatgaaattc agaacttggt cataaaattg gcgagaaaaa ccttttgtcg ccatttaccc
    13741 agatggaaga agaaagacga ataagcagaa cgtgtatgct ctgttttaca aaaaggggag
    13801 agatccatgg aacaattagc ttataaatat ccaacgaaac agccgatcaa taagaaaatc
    13861 catgtaggag tggtcggttc aggagatttg gaaatcttga tgtttccaac agaaaaaaca
    13921 gaatctactg taaaaatttg tacaggaagc gatggcttcg gcgaagtatg gaacaatgta
    13981 ttaacgagat tttttgatcg ttatccaatt tcagcagata tcgtgatcaa tgacttcggt
    14041 gctacaccag gagttgtgta cctacgattg acgcaagcaa tggaggaact ttcagatgaa
    14101 aaatagtttt gtagaattaa acgccagaga acgagtgaac gctctacttg acaatggacg
    14161 tgaattgatt gatccattcg atcaaatcat cgcgccaagt ttaccagcac aaggaatcgt
    14221 ccctgaaagt gatgacggga tcgttgtcag ccgtggcacg atcaatggca aacaagcagt
    14281 agtaatcgct atggaaggaa aattccaagg tggcggtatc ggtgaagttt ccggtgcaaa
    14341 aatcgttgct gcacttgaac atgtgttaga agaaaataaa aaaggaaatg agatctttcc
    14401 agtcattgta ctagatacag gtggtgttcg tttgcaagaa gcaaactacg gactgttatc
    14461 tatttcagaa atcggaaatg taatcattgc tctaaaacaa tatgtaccag tcatcggttt
    14521 gattccagga cgtgtaggat catttggcgg tatgtcgatt acttcagcat taatgagtta
    14581 tttaatcgca acaaaaaaag cgagagtcgg tttgaatgga ccagaagtta ttgaacaaga
    14641 agcaggcgtt cgagaatttg attctagtga caaagacttg atttggaata cattaggatc
    14701 tcgtcaacgg gtagaatcaa aaatcattga tgaattagtg actgatagtg tagaagcaat
    14761 caaagctgct gtcatcgcag caatggacga acgaaaagac acgcatcgca gtgaaagctc
    14821 agcattttat ttatcattac ttgattcttt agatctttca aaaccaatgg ccattgacga
    14881 ttacaatgaa gcaattgcta accatcaagc aaaatcaatt gacttaccag aagtagcaga
    14941 aggaaatgaa ccagctgcag caagtgttgg ttacgattgg tttgcggcac taactggcat
    15001 gaaaaatcca acttcttcta ttagtactgt gtattatggt aaatcaagta aattcataga
    15061 agaagccatc gtgacatcaa tcgtacctga tcctaaaaac ccgatgtacc gtgtacgaaa
    15121 cggtgaagtt ggtttagttg aaggtttccg catgggacaa attttggatc acgtttacga
    15181 agaagataaa gacaaaaaag tgaaacggcc aatcatcgtt gtgatcgatg taccaagcca
    15241 agcatacggc tataacgaag aattgatcgg tatccatgtg gctttggcta atagtgctgc
    15301 tgcttatgca aaactccgtc aagctggaca tccagttatt ggattgattg caggaaatgc
    15361 tatttcaggt gcatttttag cacatggatt acaatcaagc cgcttgattg ctttaaacaa
    15421 taaagaaatt accgtccaag cgatgtctaa agaaagtgct gcacgtgtga caaaacgttc
    15481 ggttgctgaa atcgaagcag ctgctgaaaa agttccagct atcgcttacg atatcaataa
    15541 ttatacaaaa ctaggagcga tctatcattt cctagaagat atcaccgacc aagctgcttc
    15601 agaacaaaat gtcagcaaag tcatcgaagc aatcaatgaa gccattcaag atgtccgcaa
    15661 tacaaatgac acgatgctga caaatcgata cacaaacgaa acagccaaaa cattcggacg
    15721 tgtcgaaaca aataaagtcc gtgccaaaat ggacgaagaa tgggatgcat aaaaaatgat
    15781 tcaagcacat gatattgtcc tttttgataa acatgaaata gaagggttca ccttgcctga
    15841 atgggtcgtt ctaactgaaa agatgttcgg aacagttcgt cgtgcgtcga cggatcacgc
    15901 agaaatacta ccgattggtt tacgtggacc tgcccgcaat cagagatggt caacagaaat
    15961 ctcaaaacat gccgtcaaac aagtcattca tccgtgggac atcatcgaac aagaatcgta
    16021 tagacaagag aaaatcatgg attatcctgt ttatcagcaa tttcatgctg ctagaaacat
    16081 attatcagga tgtaaatggg gaatcggcgg cagcttagga tttgaattat cgactgggat
    16141 tccggcagta aaagaaacca gtgattttga tttgctgctg tacgcaaatt caccgattga
    16201 attgccaatt caggtaattc aatcgcatcc tgcttttttt gagcaattcg atacccaagt
    16261 agtgactcgg caaggcggtt tttcactaaa agagtatttg agagagccag agaaaaaaat
    16321 tctattgaaa acagtcgaag gacctaaatt aaccaaagaa ctttggtaat aaagaaaaag
    16381 agagagaaag agatgtttga aaacaaaaaa atcaaaatca acgtaagtga cttccagaaa
    16441 gtatcagctg taacggctgt tatgatgcaa acgatattga gctttgcttt ggcaaacagc
    16501 cacagcgcaa caaatacagc ttttcttggt accttttacg tcatcgttaa atacacagca
    16561 ccaatgttta tttttgcaat tgtttataat atggtaaaaa caagtcagca tttgtcttat
    16621 tgggaatttt tgaaagaaaa gttttttgaa ctagtcgttc cgtatcttct atggacgacg
    16681 gcttatcttt ggctatttcc agcagtccaa caacaaactc cgtatacgga tactgcaagc
    16741 tttttactga aatatgtcac aggtgatgga gcgcctcatt tatggtatac cgttatgatg
    16801 ctgcagatcc aattgttcat gccgtttttt gtttggctcg gttacaaagt atttgctaat
    16861 aaaaaatatg tatggccagt attgattggt tcaacgattt tatatgtcgc atggtatctg
    16921 ttctatcaaa cacaagtatt gactgggcct tatcatgaca gctggtactt attagatcgg
    16981 tttgttgcta gtttcatgat ttatggggta gccgcatttg tttatcacga aaaagtctat
    17041 caatatttgg acagagtacg ttatcttttc ttacctgttg ccttagttat cgcgttcttt
    17101 tctgtccgtt cattgctcgc acatccagga gacttgagct ttgcgaatgc accttacttg
    17161 aatacgatcc aaagtttata cagtttagtc atcatctttg ctgtcttcat aggcgcttcc
    17221 aaaatgattg taaacgattc gccaaaattg ccattgttca aatggttgtc tgtttatgct
    17281 tatcgtacgt atttagccaa tgtatttgtt ttccaagtac tgttattatt gtttaaagat
    17341 agttggctgc agttaccttc aggagtcatg attcttgtag cttatctaat gacggcaagt
    17401 tgtgcatttg ctttaagctg gttacttcat atcatttggg tagctatcaa aaaaggtttc
    17461 agcaagtaat agtaggaaga aggagtgagt gtcatgataa atgacgaacg aaaaaaagca
    17521 gtgactcagc aactcgctgc gttggtagag gaagcattga tcgcagaagt aacattaagt
    17581 ccaaaacctg gattagtgga tgcactggat gcgggtgcac attccgatat ggactatgct
    17641 ttatttctta agtctgctaa gacgctaact cctttttttg aagaaatggc tcaaatagca
    17701 tggcatcatg ctattgatca ggagttaaga gaaagaattg ctgagattgg gcgaaaagcg
    17761 gaaaaggcaa tgctgattgc tacaaatggc atcaataccc ataaaggagc gatttgggca
    17821 atggggctat tgatcagtgt cattgcacaa aaaatcagta tggaacagcc tttttcttta
    17881 tcgaaaatac ttgatgatgt cagcaagctt gctgcttttc ctgatacaaa atatcgtcat
    17941 aaaaaaacca ctcatggtca tagggtgaag caaaaatatg gcgtaaatgg tgcatatgaa
    18001 gaagcgatat tagggtatcc gcatatcagg cttgcaattc aagcagctaa ggagctagat
    18061 aatgattcat atgtacagaa acaaatgcat atgttgttag ttttgatgag ttcgctagat
    18121 gacacatgcg tattgcatcg cagtgatcag aaaacgttag tggaaatgca aaaacttgct
    18181 catgctgcta gtcaaagtgc tttaccaaat cgtccattta cagcactgtt gcacttttgt
    18241 caggaaaacc aaatctctcc tggaggaagc gcagatctct tgtctgcaag cttgttcatg
    18301 ctgaagatag aggaattatg gactgccgac acatacattt gtccgatgtt actcaatgac
    18361 taaataagac aaaattgcta aaaaaacagt ttatgcatct ggttattgac tcttcctttt
    18421 agcaaggcta tcataaaaat agttttttgt aataaaagat aacgaggaag acaatgaaaa
    18481 aaatcaatta tttagcaatc attttgttag tgggcctatg tttgtttgct ctgccgaccc
    18541 aaggattcgc tgtcgcgggt ggtcatggtg gaggtacatc tagcggtcga agttcgggca
    18601 gaggttcatt tggtggtcgt tcatatgggg gcagttattt tggcagtcgt tcttacggca
    18661 gagattctta tgggtattat ggtccaggta caggtccttc tagttatgag caaacgggat
    18721 ttcttgcatt agctgttttg tcagtaggag gggtttctgc tttttctatc gtcaagaata
    18781 aaagacaaaa gaaaaggctg aaagcggaga tattgtcccg catgtcagga acggctaaag
    18841 aaaagaaagc acagtttctg gaaatccaaa agatattcat gaagatccaa tccgcttggg
    18901 aagaagaaac tcctgaaaaa gccagaagct gttatacaga caagctgttt gccgaacatc
    18961 agaaagttct gcaaaaaaac aaagcagacg gtgtaagaaa tcatactaaa aaaataacta
    19021 ttcaggaagt aggaaattat cgacagatcc acgaaaatag ttttgccatc cgaattgatt
    19081 tcagatgctg tgattattca gtcgatcgaa aagatgggcg attgatctca ggaagtaaga
    19141 cacaacgaca gtatttttct cagatatggt attttgattt ttctgagaaa gaaaaaagat
    19201 ggcaagccga ttttattcag ccgattatgc tggattgaca ggaaatattt atgaacggag
    19261 ttgtgacaaa agccttgtcg cagctccttt ttctgaataa acggtgtgcc agagatagcc
    19321 tatcggcaat aaggcacgat tttgtaaaat atgggaagcg atttttcaaa atcgcttctt
    19381 atcgctcaag gctgaacatc tctgtcacaa cctctccact aaatggtgtt taaaagcttg
    19441 catctgcgat aataagaaca accaaacgaa aaataggaag cactatttta gtttagttgt
    19501 tcttattact tgatgcagga cagctttttc acaacctctt ttttgtatag atgggcaaaa
    19561 tttttgtaat aataggcgta tgtctttttc gttgaggaga tgaaaaagca tatggcttat
    19621 tttttgtttg ctttgcttac tttctttcca cttcaagtgg cagaaatatc tactttttat
    19681 tatgtaagcg gaaccatata cttgaaatca gaaggagatc atttctatga aaacaagaac
    19741 aattgaaata cttcacagaa tcatgacagc ccaatatcca gtaaaagcaa aacatctagc
    19801 aagtgagttc aatgtcagtc agcggacgat ccgtcaggaa gttcttgaag cgaatatctg
    19861 gttgagcagt aaaaagcttc cggagatccg tacaattcgc aacaaaggtt ttttgttgaa
    19921 gctggaaaag gaaaagcaag ctcgattaga aactgaaata aaagatgtga aagacggctt
    19981 tttgaatcgg cgcgaacgta tttttgatct agttttagcc gttgcttaca gccgaatccc
    20041 gatccatcta aacaaaaaag aagaagaatt tcaaatctct aaaagtacat tagatgaaga
    20101 tatgagacgg ttacgagcaa cactggtcag ttatgggata gagatcgtca gttatggaaa
    20161 gcaaggactg gtttataaag gttcagaacg atctatccgt acgatgatct atgattttat
    20221 caatcagaat ctgggaatga ccgacttctt tatgaatcaa gatgcacaat taacaccggc
    20281 tcaaaaaatc tttctccatt attttccttt ggtggaaatc aaaaaaatac aggagatcta
    20341 ttccaataag ttgttgaaac aagaagatga tatttataaa aaacaaatcc tgctttttac
    20401 attgatctgg atccagcgaa tcaggaaaca tgaatttatc tctgccatta attggaaaaa
    20461 tacagaaata aaagacagta gcttttctgc atttattgac cacatgatcg aggaatttca
    20521 attggacaat gtcccgcaag tagaaagaaa ttatcttcgt ttcactattg agacgttcaa
    20581 tgctagagat atctccaatt caatcgagtg ggtacaagct caattactaa cgatccaatt
    20641 gatccaattt gtagagaacg agacacacgt acctttccat ctaaaggaag aagctttatt
    20701 cgaaaatctc tataagcaca tggctgcact gattgtaaga atcaagaatc atatccaagt
    20761 catgaatcca ttgaaagaaa acatccgaac aaattatttc ccaatctacc gcgcagtcac
    20821 tcattttgtt cctacgatcg aagaagtaat tggtggcaag atactggagg acgagatagc
    20881 ttttcttgtc atccactttt cgacgatcgc cagtgtaatc aagcgagact tgaattatgt
    20941 ttataaatca gtcgttgtct gtaaccatgg gatggctact ggaaatctgt tagcagagaa
    21001 tctgaaagaa aagtttcctc agatcgagat tactgcagtt ttaagttcaa aagaaatcga
    21061 attagtagat aaattggatg tcaatctggt tttcagcacc tttcaattga attatcgaaa
    21121 taagccgctt ttagttgtcg atccgatttt aactgagacg aatatcttgg ttatagaaga
    21181 ctttttgaaa agaaatgaag aactacagcg gttagagcct aacagtcatg aatcgacgga
    21241 gttattcact caaataatag atgtcatgaa agaaagtggt ggccgagtag atcgaatcat
    21301 ctatggcaag ttagaaaaat tattcgaaac aaacaattta gaaatcaaca aaagggagat
    21361 ccagcctatg ttaaaagata ttttgacgga cagcaatatc atgatcaaag aaaaagccac
    21421 tacttgggag gaatcgattg aactagctgc tagaccattg gttaaagaaa acattgtcga
    21481 agagcgctat gtcgaagcga tgattcgtgc agtgaatgat tacggaccgt atatcgtgat
    21541 tggcaaacac atggcactag cccatgcccg accagaagat ggggtcaata aattaggagt
    21601 cagcgtagct acgattgagc aaccaatcga tttcggtaat cctgaaatgg atccagtaaa
    21661 gattattttt tgtttggcag cagtagactc ctactcgcat ctgaacatca tgaaagaact
    21721 aattgaattg atcaacaacg aagagaagtt ggatcgattg attgaatgca caaatatcga
    21781 agatttcaaa caactgcttt tttcagtagt tgagaaataa taaatgatac gggggagaac
    21841 aaagatgaac aaattgaaca ttttattcgt atgcggtgca ggtttaggaa gtagttttgc
    21901 agcacagatg tctgctgagg atgttttgaa caaattagga gtagaagcca aactggacca
    21961 ttgtgatatt tcttccgcag tttccatgaa accagatgtg atcatcacag cagaaaattt
    22021 tcgttcgcag ttcgaaaagt tcgcagttga tcctaaaacg gcgatgatct atttgaaaaa
    22081 tattgtttca aaaaatgaaa ttgaagaaaa aatcacccca gttctgcaag ataagggagt
    22141 tatctaaata caaaaagaaa agagggtaaa aa
//
LOCUS       DAZKNV010000045        22027 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000045 DAZKNV010000000
VERSION     DAZKNV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.045"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..1369)
                     /locus_tag="ACG8M1_001934"
     CDS             complement(59..1369)
                     /locus_tag="ACG8M1_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFQ0422616.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1381..2799)
                     /locus_tag="ACG8M1_001935"
     CDS             complement(1381..2799)
                     /locus_tag="ACG8M1_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0422617.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3039..4607)
                     /locus_tag="ACG8M1_001936"
     CDS             complement(3039..4607)
                     /locus_tag="ACG8M1_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFQ0422618.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4611..4892)
                     /locus_tag="ACG8M1_001937"
     CDS             complement(4611..4892)
                     /locus_tag="ACG8M1_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFQ0422619.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4889..5812)
                     /locus_tag="ACG8M1_001938"
     CDS             complement(4889..5812)
                     /locus_tag="ACG8M1_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFQ0422620.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5809..6687)
                     /locus_tag="ACG8M1_001939"
     CDS             complement(5809..6687)
                     /locus_tag="ACG8M1_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFQ0422621.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6674..8011)
                     /locus_tag="ACG8M1_001940"
     CDS             complement(6674..8011)
                     /locus_tag="ACG8M1_001940"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFQ0422622.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8014..9117)
                     /locus_tag="ACG8M1_001941"
     CDS             complement(8014..9117)
                     /locus_tag="ACG8M1_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0422623.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9191..10699)
                     /locus_tag="ACG8M1_001942"
     CDS             complement(9191..10699)
                     /locus_tag="ACG8M1_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0422624.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10665..11357)
                     /locus_tag="ACG8M1_001943"
     CDS             complement(10665..11357)
                     /locus_tag="ACG8M1_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFQ0422625.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11379..12353)
                     /locus_tag="ACG8M1_001944"
     CDS             complement(11379..12353)
                     /locus_tag="ACG8M1_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422626.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12653..13525
                     /locus_tag="ACG8M1_001945"
     CDS             12653..13525
                     /locus_tag="ACG8M1_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422627.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14107..16305)
                     /locus_tag="ACG8M1_001946"
     CDS             complement(14107..16305)
                     /locus_tag="ACG8M1_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422628.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16537..17529
                     /locus_tag="ACG8M1_001947"
     CDS             16537..17529
                     /locus_tag="ACG8M1_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0422629.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17589..19010
                     /locus_tag="ACG8M1_001948"
     CDS             17589..19010
                     /locus_tag="ACG8M1_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFQ0422630.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19003..20502
                     /locus_tag="ACG8M1_001949"
     CDS             19003..20502
                     /locus_tag="ACG8M1_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFQ0422631.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20541..21935
                     /gene="uxaC"
                     /locus_tag="ACG8M1_001950"
     CDS             20541..21935
                     /gene="uxaC"
                     /locus_tag="ACG8M1_001950"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFQ0422632.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6669 a         4494 c         3823 g         7041 t
ORIGIN      
        1 cattaaaaaa aataaaggtc aagctaaaat attatttaag cttgacctta ttataatttc
       61 aacgattgtc aaaagtattg tttgcagctg tgttgccagt ttctatagat aaatcacagc
      121 ttttgaaaca taagttttgt actgcttcga ttcgcccgaa ttcttttgca gttatttggc
      181 aatgagaaaa gcagacatct tctataggct tttcaggaaa tgctactaaa tcaaaagctc
      241 gggaaggaag tgagtaacct ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt
      301 tgactttcgt catttgcttt gattcaggta tttcttcagc cactgcttgc caactttctg
      361 gcatttgagc aaggtcattg ctattttttc tattgtattc attatgccag tccattatcc
      421 aagaaaaagg aaattgtaca tcaatcatat tcagattttc taccctgata ttttcgatca
      481 ctccccctct ttcttttgaa gatttcattc gaataccaca gtctgactga aaaaaattga
      541 tatcgtgaat atatacgtca ctaactccag cactaacttc gctaccaata gttacaccgt
      601 atcctgaacg gattttacat ctagcaacct cgattcttga tgattttcga ttgactcttg
      661 caccattgcc atctctgcca gacttaatag caatacaatc atcaccacag gccaaatcac
      721 attcatagac acgcacattt gttgaagaat caatatcaat cccatctgta cttggtccat
      781 cattgttgcg gatgattact ttttctacta atacatcgtt agaataagtg atttgcaagt
      841 tccaaaaacc tgatttctga aaaatcaaat cacgaacaac aacatgttct gcatgataca
      901 gtaaacaagc gcgtggacgt ttaatagcat aatccgcaat ccaacgaagt cccttttgat
      961 cgtattcagc tcttgtcccg cttttttgat cttttcccca atacagctcc caccaatggt
     1021 ctccttgacc gtcgattatt ccttttcctt ctataagaat atctttcgcc gagagaacat
     1081 tcaaaatcgc tgctggccat ttcatttcta cgccggctac tcgtgtatcg atttctggaa
     1141 atgcttcgat atctgttctc cccttgagga ctgcaccttc ttcaaagata agatgactct
     1201 tatcttttaa aaaaagggct ccgactaaat aaatgccttt tggaataaat acaggtaagt
     1261 gttctttcgc accttgatcg attgcttttt gcagtattat tgtatcatct tgttgagtgt
     1321 cgtttgtttt aaagttcaaa gcattgataa tccctttttt tgtccgcaat acgtttctcc
     1381 ctatctttca ttgatttttt tcaattcttc accaataaat acagtttttg aacgattcag
     1441 tgggtaacct actagcaaaa tgattgcgga tacaaataag cagaatgctg gtaacaagtt
     1501 tgccatcgta taaatccttt cttgtactaa aactgattgg atggctccac ctgttgtaga
     1561 cgattggtaa ccaatgagtg ccagcataaa tccgcctacc gctcctgcac atgcttgtcc
     1621 tacttttctc gcaaaagaat ttactccata tactgttcca tcttctctta agcctgtctt
     1681 atattgatga taatcaatca cgtcagtaat gaatgcccag accatcaaat tgaataaacc
     1741 agatcctaaa gtagcgataa ataaaagaat cagatatacc catgcatttg ttatatgaag
     1801 gaaatacatc agcaagtaca tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt
     1861 tttaccaaat aattttgtca gctttgtagc aaatggtgct aaaactacta ctgttccgta
     1921 agtaaataaa agagcaacag acattgcttg tttattatgg aagtaatcat tgaataaata
     1981 agtcatattc gtcccagcta aaatctgatt gatcacaatg aaaatgtcaa caatgactaa
     2041 aataatcagt gctcgattag ctaacaaacc ttttaccaac tgagaagcag atactttttc
     2101 gtttttgaca actcttactc tttcagtagt caatttacaa gttaacatat atgcgacaaa
     2161 tgctattgca gcacatccga ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg
     2221 tccactcttg ttatgggtat acattaaaat cggaatgaag aatcctgtag ttgatccgcc
     2281 aatcgcagaa ccaatgcttc ggaacgtgga caacgaggtg cggtcattag gatttgagct
     2341 aattgctgct gccattgctc catacgggat attgattgtt gagagaaaaa tcccataaac
     2401 aatgtatgaa acaaaaatat aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg
     2461 caaaaacaaa atgacagtca ctaagcaaaa tggatacttc atttttctga tccaaggaat
     2521 aaatcggcca gtttctgtta actctgagac atcacataat cttccaacca tcacatcagc
     2581 aaacgcatcc aaaattctcg aaatcaagaa taacgtacct acgattgccc ctgaaacgcc
     2641 aagaacattc gtataataaa tcatcaagaa actattgact aaacctaaaa taaaacagtt
     2701 acctagatca ccgaacatgt agcctatctt atcggaaatc ccaaattcct ttttttcttt
     2761 ttttactgta tttgctgtaa cagcattttg tgaaagcatt tgaattcctc ctacctcttc
     2821 tagtaaacgt tttcaaaatt ataactcttt ttttcttgtt tttatattca caatgttggc
     2881 tttttattgc attatcttga cagataaaaa acaaaaaata atctaaaaac attgatgcat
     2941 aagattgata acttttttta cataacaata tatacaaaca aaaaaattca ctaactagtg
     3001 aaaataagtt agtgaacctc atttattaaa gaattaaatt acagatgatc ttttccatca
     3061 tacttgaaaa actcaaaatc agcataactt cctctttttt tatttagatc atgcactgct
     3121 atcccgataa aatttccagt aaaccctcct gagagtatac acatgttttt ttgcggacct
     3181 actttcttcc attcttcagt tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt
     3241 acagtgactt tcaaaaaagt cttcttttct gtgagtggaa tcgtccaatc ttctatttgt
     3301 gctactccgt tttctgattc tatcatacgt aggcattttc ccttgtcctc attccaagta
     3361 acataacaat aaatataatt ggattcattt aagtacagta ccagtccagc catctgatta
     3421 aaattattag gcatgtattc aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga
     3481 atagctaaca aatgatgttc gaaggtagat tgaagagatt caccggaaat cagacgtaaa
     3541 aaacctggtc tacattttgt atcacaccaa tcagcatttg gcaaaatgcg tctggcattc
     3601 cagttcttct ttagctctcc ttcaaatgta tccataaact gatgatcttt ttcttgttgt
     3661 acctcttcat ttgtctcaat cattatttct tccatcggag ttgtctggct atctttaagt
     3721 cttaaccaat cgtcggacgt ccaatacact tcttgaatag cggtttctct tcccaaaata
     3781 gccgcaccgt ttaatggtct ggtacaaaga tatgtcatgt accatcttcc tgacggggtt
     3841 tgtactaagc tcccatgtcc tgtacattgc aatgtagaag caggtttgtc actagctgtc
     3901 agcataggaa aaccaggatc aagctcgtaa ggaccagtaa tattctttgc tcggcaaact
     3961 gtaactgaat gtcctcttcc tgtaccgcct tctgccgtca tcaaataata atacccgtta
     4021 cgaaaataca aatgtggtgc ctccgttttc gctaattctg tacctgcaaa tattttatag
     4081 atgggaccat caagcttctt cttctctgca tcatattctt gtaatacgat accgctggat
     4141 ttattcggtg tgtccagacg ataatcccat agttcattga caagccattt ttttcccgtt
     4201 tcaagatcat ggaacaaaga aggatcaaag ccgttactat ttaaataaat tggttcggac
     4261 caaggacctg tgatctcaga tgcagtgatc aaataattgt ggacatcttt aaacggacgg
     4321 cctgcacttt tgacatctgt gtaaacaaga taaaacaatc catcagcata actgatctgt
     4381 ggcgcccata tacttccatt tgtaggattt ccttgcaaag atacttgagt ggtcaaaata
     4441 tccgttgtat gtgaccagtt gactaaattt ttcgactcat atactcggat tcctggaagc
     4501 cattcaaaag aggagacaat aatgtaatac cgctctttca ctcttaatat attaggatct
     4561 ggattgaatc ctcttaaaat aggatttttc actttgatag tctgcatgat tcaggctcct
     4621 tttctcattc ttactcgata taaactgaat gccccagctg ctaaaaaagc aagtgaaata
     4681 aacaacacaa cggcaaacag accagtcatg tcctgtaata atccaaatgt attttctaaa
     4741 gacaaagttg aatgatctac agcaagcgac tgataacttt ttttaaactc tgacgcagac
     4801 atattactta aagtaactgc taacccgcca aagaaaatca aagatagact gccaccgacc
     4861 attcctagca atagttccca ttttcttttc atttctgaac cccctgcttt tctaaatgta
     4921 tccattcagg tcttttgatc gatgtttcat aattgttatt acgttcagag aatttgacag
     4981 tctgttcatt tttcttgtca tcccaattat cccaaccagt tgggtgaaca tgcccaccta
     5041 tcttacacgc ttcaaataag acatttgcat acggacgcca cggtcttcct aaatagacgt
     5101 ttctagtatc aggttctgca gtcaaggtac agctttcaaa acgataccct gttttttgat
     5161 ttttcggcgt agatgctgct gtgatgtatc caggattttt actggctaag ctatggatat
     5221 gacactgatg aaaaacggca tctgccccac caaatatgaa atccaccgtt ccttcaatcc
     5281 agcaatattc ataggtctga cgacaatact caggattggc agaagccggt gtacaaaaag
     5341 gagtaccatc tttttgcaaa tcaggcaacg gacccgtgca taaggtatcc tgataaccag
     5401 atagtcgaca gttttttaaa gatacgcgat ctcctgaatt gaataaagca acagcctgtc
     5461 ctaccttttc tcctggacct gctgtatttt cgatgtgaag attttctaat acgacattcg
     5521 atccttctaa gaaaaaagta gcacttcgga aagtccctaa ctggctaccg tcaagatact
     5581 cctgttttgc aaaacgatta ccggagataa ctactgttcc tgctcccaca agtttaaaat
     5641 tggataatct gctttctata tattcatcat atcttccttc ttttactatc aagacctttg
     5701 gatggctatc cggcaggcct gccaaataat cgattccttc ttggatagtt tcaaaatccg
     5761 tcggggtatc tatagcattc tttccaatta tcagtttgtc tttcatcctc ataaatgctc
     5821 ccttatgaat tgtttccaaa tatttctcat ttcttgtgtt tccatatgac cgcctgttaa
     5881 agaaaaagaa gaaaagtttt ctggactacc cattgattga tactttttgt ccagcccttt
     5941 tctcagcttc agtacgcctt cgtccaagca catcgtatcg ttttttccaa ctaagctaag
     6001 acgagggcgc ggagcgattt tttcttggat tgctaacgtt gtataagctg tcaatagatt
     6061 tggcacatag taataaaacc catgatgatc taggcggcga tgtagcaaaa gtgtttcgat
     6121 gtccacctgt gccgctagat caatacaaac tttgacacga gaatccaatg ctgtcaccca
     6181 ccagcttaat aagcctccca tagaaagacc aatcgttgcg agccgttgag tatctgtgtc
     6241 ttcccttgtc tccaaataat cgatcaagct gatcacatca taaatacgca ttccccataa
     6301 cgtttttcct gttaataaaa attgtttgaa caactcgctt tcagaaatac ctccgcgttc
     6361 ttcaaatccc caagcatcaa tcgaccaaac agcatatccc attcctgtca gtacttctgc
     6421 aaaagatgga gaagctaagt aaggagcacc atggatcaat tcacttttcc cgactgaaaa
     6481 atctccgccg tgagaatgca ggtaaaggac cgtcggaaac ggtccttctt tttctggata
     6541 agcatagagg gctggtactg tttccaattc atttaagtac aattgatagt attcaagcat
     6601 aaaaccgttt tgtttttctc ggtataatcg ttttccacta ggggtatgtc tgctagatgg
     6661 agcacctaaa aaatcattca actgcataag caaagttttt acgaacaacc agttcatcca
     6721 tattttctga ttgatttgat tggaatttct caatactgat ttctttagta ttttctaata
     6781 gaaatgctgg tccctcgtga ttttcaatcg acatctggtt aaaggaaacc ttacccgcaa
     6841 agccaatata aaatccttgt ctgctcattt cctctattcc tgtcatcata gcaggaacac
     6901 cgggaactgc atcttgggcc atcgagacat cgatattgtc aaatgtgatt tcttgtatga
     6961 attgttccgc taatccataa ataaaacctg cagaagcatg gacattcctt gccgtgatat
     7021 tcgaaaaatg gatccttctg aatgctgatg tccgttcatc tatcggataa gccttttttt
     7081 cccatacata cggttctttc cctcgcggac cacagaaata ataaagattc agtataaatg
     7141 gacacatcac attatccatg actatattgg atactcgaat atcttcaacg atcccgcctc
     7201 gacctcgtct agatttcaat cgtattcctc gatcagtttc ttggaagata caatttgaaa
     7261 tggtaatatt acgaatacta ccactcattt cacttcctaa tacgacaccg ccatgtccat
     7321 ggaccatcgt gcaatttgtg atcgtgatat tttcgcaagc gatcctttcg tacgtatctt
     7381 cagtccctgc cttgattgca atacagtcat ctcccacgtc aatatggcaa ttactaatac
     7441 gcacattttt gcatgattct ggatcaattc cgtctgtatt tggtgaatcc gctgggttca
     7501 agatcgtcaa gttatcaaac gttgcattac tgcaaagaat cgggttgatc gtccaacttg
     7561 gtgactggat caatttaata tctttcacag taattcgatg acagttatgg aaactcatca
     7621 atttaggacg aggataagcg agattatctg gttcatttct aaaagtatgc caccattttt
     7681 ttccatttcc atctaatgta ccgaaaccag tgacagagat gttctctaca ttttgagcat
     7741 agatacagga agcataaact tttcgatgga ctccttccca acgtgaatga acaacaggat
     7801 aatcttttgg atcgtcagag aatttcagaa ccgctcctgc gcttaaatga agttcgacat
     7861 tgctttttaa aaataaagct cctgttagaa attcacctgc tggaacaact acggtcccgc
     7921 ctccgtcact tgctgcagca tcaatggctt gttgtattgc ttcagtattc aattcatcaa
     7981 ttgatgcgcc aaatgtcaaa atatcataca tatttataat gcctccactt caatcaatgc
     8041 ttgcaagaat gcaccaacgc ctttttgatc attacaaata attggttcac tgatgtagta
     8101 agcatatgaa ccatctcgct gatctgctcc gcctaaccct gctacttgac agtttttatt
     8161 caagttcagc cagccttctt ttgtttccag aacaaattca tcaagtaatc cttgatgtga
     8221 tttcttcact tgtggaagcc attcttcttt gttcagcagt cccaaacgta ttcctttagc
     8281 cattgcgtaa acaaacatac tactgccgga agcttccaga taatttcctt tccgttttgt
     8341 ttctgttgtt acttgatacc atgtcccgct gttttcttct tgatatggaa gtaatgcagc
     8401 cagtgtcttt tctagaattt ctttcagcaa agaacaatct gtttcttcat gaagtaattc
     8461 ataggtatct gctgcagcca tcaaatacca gccaatcgat cggctccaaa aatgatggga
     8521 tagacctgtt tttggatcag cccatggttg gaccttcttt tcatcccatg catgaatcag
     8581 caaatttgtt tttggatcga atagatgttt ataactgatt tcaaactgtc tcaaaacatc
     8641 ttggtaatct ttttcttcac taaaattctg gataaattca gcataaaaag gagaacccat
     8701 atataagcca tccaaccaaa tttgataagg ataaatttct ttatgccaaa aagctccttc
     8761 ggatgtgcgt ggatggtttg ccaactgctg ggaaaggagt tctgctgctt ttttatattt
     8821 ttcttcgcct gtttctttgt acaataaaaa gaaaagcttt cctgtattta catggtcgat
     8881 attgtattct tcaacgctgt agccacggat cgttccatct tcttgcacga aatagtcgat
     8941 attgtctttt atgaaatcaa aataaatttt ttcttgggtt cgttcccaaa gtaattggaa
     9001 ccctttaagt acgacgccat agtcataaga ccattttcct ttataccact tttcttcata
     9061 taagcgaggt gttctttcca tgatactttt tgctaatttc tttgaccagt tttccattat
     9121 ttgctctcct ttaaaaatta aaataggatt tgggacaaat accaagaagt atttgtccca
     9181 atcgtctata ttactgtgcc gctgctttgt atgcttcctc gtactcttgt gtgattcgat
     9241 cgcctccttg tgctttccag tcttctacag cttttttgaa tccatcttcg tcaagctgtc
     9301 ccatgatgta ttgcaccgta gcatcaatga cgattttttc aatttctgat cctacttcat
     9361 tgttcgtcgg tgaatccaat ggcacagaag gatccattac agcaaattct tcattttctt
     9421 tgatcaattg attagagaat tctttttcag ggtctgtatc tttgaaagag aacgtcactt
     9481 cactaggacg agagcttgat aacggttgca cctcttgttg ccaaagatcc atatcgataa
     9541 attcgataga accatcatca ttcaattcat aatgcgttcc ttcgataccg ccagtcatca
     9601 atttatacac atcttcttct aaaagatcat caacaaattg aagtaatttc ttcaattgtg
     9661 cttcgtcttt tacttgagat ttgggaaatg ctagcaagcc gccaatacca tttccttctg
     9721 accaaacatg ataaccgccg ccttcaccat ctgagatctt gtttacaggc actaattcca
     9781 tatcatcttg aataccttga cccatcgtct tcagattctt gatatccacc attccagtgt
     9841 agattccagt tcttccttgt gcaaattgtt cttgctgatc agtcttttgg gtaactgcaa
     9901 agtcttgtgc caaatagcca ttctcaaata gatctcttga aaaattcaaa gctttcatat
     9961 actcttctgt atcaaattct ggagtgaatt tgccattatc gtctacagcc cagccatttg
    10021 gtgctccaaa ataagaagtg aaaagtttaa agctggtata acgaatatca ctaggcgcac
    10081 gatcgccaaa accaactgtg tcgtccacac catttccatc aggatcgttt tctgtaaatt
    10141 gtttagctac ttcataaagc tcatccatgg tagttggaac atctagtcct agattatcca
    10201 accagtcttt tcgaatgact aagccagcac gagcgtagtc tttttgtatc ggtacgccgt
    10261 acaaggcacc gtcgatactc gcagcttcga ttctatcttc agaaatttga cttaaatttt
    10321 tatagtcttt taaatattct gatacatccc agaatacgcc tgattttaac gcattgcgga
    10381 cagaagagtt tttcaacatc gcaatttgaa gtgtaacgat atctcctagt tcatcagaag
    10441 ccaatgcagt tgttaatctt tcttcttttg aagcatcagg aatccagttg aatgtcagtt
    10501 ccgtatcggt tttttcttcg atcaagttca caatcgtgtc tgtaggcggt gaagcatgat
    10561 gcaaaatatt taaccaagtg attttagctt ttccatcttc tgtctctgaa gaactgttac
    10621 ttgaactgct gccgcatgcg gcaagtgcta gaattcctgc aaaactaaga cctaatttta
    10681 cgagcgttgc ttttttcata aattttctcc ttcactgttt taataatatt tttgttttct
    10741 tctgtttttt ctgtatatga gttcttccat tccaaatggc aaaatataga atttgctgtc
    10801 cacgtgactg cggaaaagaa gagactgcca ccgataaagg ttaaaacacc tggcattgtt
    10861 tggatgatca tcagataaat ccctaccata cttaatatca acactaatga gtaatgaaga
    10921 tgtgagaatc cgaataaaaa tgccattttc attttgaaaa aatatccttt ccaatcataa
    10981 tgagccatga ttgggaaaat atagagtgct gagagcacat atatgaacgc agcaatatac
    11041 aaagcgatcc taagatacca attgtgtatg aaagaaagat ccacaagtaa aacaatcccg
    11101 atggcgccat atatccagct catcagcaag gtttcacgat agttttcttt aaaatatgtg
    11161 aagtacgttt tcgtcaaagg aaacgtttct tttgagcgca gccattttct aatcactgca
    11221 accatcgcat acgatgcagg accgaaagta aaaactccca aacctgcgat gactaaaccg
    11281 ccccacagaa aattcaaata aaccaactgt aaaatacgat ttagccttcc gtttatttta
    11341 tctaatgact gcagcatatc tttccctctc tttctatctt agtaaacgcc gtcttctcct
    11401 agctttttgg caatcttatt agctaaaatt accataaaca atcctacgac ccctttaaac
    11461 aatcccattg ctgtactgaa acttaactgt ccattcttca atccagctgt ataaatatag
    11521 gtgtcgaaaa tttctgcaac gcttcgattc aatgaattca ataacaagta catatgctcg
    11581 aaccctaagt ctaatgtctg accgattttt agaatcagca aggtaatgat tactggacga
    11641 attgccggca atgtaacatg ccatgttttg cgtaagcgtc ctgctccatc catttctgca
    11701 gcttcataca actgtgtatc gactgcagtt atcgctgaaa ggtagatgat cgtagaccag
    11761 cccaactctt tccagatcac ttgtccgata tatactgtgc gtgtccattc aggggatgtt
    11821 agaaaactga ttttttcaaa tcccattgtt gcaaggaatt cattcaatac ccctccgtca
    11881 acattcaaaa atacataagt aatcgaaaca atgattaccc aagacatgaa gtgagggatg
    11941 taaatgatcg tttgaatccc gtttttcaat cgtttgttcg ttacttcatt taatagtaaa
    12001 gacaaaatga ttggcatcgg aaaaaacacg aagatattta atccgaacaa gatcaacgta
    12061 tttcttaata atgtaaagaa tgtcggttct gtaaacaaac gaatgaaatg tttgaaaccg
    12121 acccaaggac ttcccattat tcctaaaaat ggttgataat cttgaaaagc aataacgagt
    12181 ccccccatag gaagatacct aaaaatcaag aaataaagga ctcccggcag aatcatcaca
    12241 tataaaaatt tattcgtttt gattcctgca attatttttt ttcgtcttct gagcttttct
    12301 tcttttttcg atagcgtcag ttgaaatggt tcttgtttct ttacactttc cataagcccc
    12361 tccttagttt tgtgaatgtt tgctgcttat gacttcatga tagataacta tctgaattac
    12421 gtatataatc atttttatcg taagtaaaaa cgcttacata gcaatgattt ttgtgctata
    12481 caaaacgata aagtgtattt tttcacaaat aaactacgca tagcaaacct tctatttttt
    12541 tctatctgac acttagcata ggaaatgatt atatacgtaa tctttcaccg atgataaatt
    12601 gaacatatag aaacagaaac atttaattta ttttgaggag gagcctatct atatgaaaaa
    12661 gaaagtctct ataggagaaa gaagttttac acttttcaac aatacgtttc taattttgct
    12721 agctttgatc tgtatcgttc cttttttaaa tatcatcgct acatcttttg cttctacaca
    12781 agaagtcgtc gcgaaaaagt ttatcctttt tcctactacc ttttctttag acgcgtatcg
    12841 ctacattctt tctacgccga ccatttttag agcacttgct gtttcgattg gtgttacagg
    12901 tgtcggaacg atcgtcagta tgtgtgcaac ttcactgatg gcctacggtc tttccagaaa
    12961 gtatttgttt ggtcgaggtt tcgtcaactt tcttgttgta ttttctatgt tgttcagcgg
    13021 ggggatgatt ccaacgttct tagttgttcg ttctctaggg ctggtcaatt cttactgggc
    13081 catgatcctg cctgtggctg ttaatgcaat gaatatgatc attatgagaa actttttcca
    13141 agccttgccg gatagtttgg aagaatcagc aaaaatggat ggttgcacag attttggtgt
    13201 atttttcaaa attatgctgc cattagcttt accgtctatt gctactatct cgctttttta
    13261 tgctgttact tactggaaca cttatatgac tgctattttg tatatcaacg attcatctaa
    13321 atggccgata cagattcttt tacgccaaat cgtcattgta tcaagtggga tgcaagcaga
    13381 aagtagtgcc gttgatgtga ttccaccagc acaaacagtt aaaatggctg ttatcgttat
    13441 tgcaacagtg cctatgctga ttgtttatcc ttttgttcag aaatattttg tcaaaggagc
    13501 actcgtaggt tctgtcaaag ggtgattatg tactgaacgc aaaatggtag ttgtgtcaga
    13561 agtggtcagc ttcaagaaat aagaaggcat ttacgaaaat tgcttcttaa atttttgtga
    13621 aatttcggct tatttttcga agaatctact cctggaacac cgtgtatcag aggttgtgaa
    13681 agagacgttc agccttgagc gatgataaaa actctcacaa acattgcgac gagtaaccca
    13741 caggagcaat aagaagcgat tttgaaaaat agcttcccat atttcacaaa attatgcctt
    13801 attgtcgata gcctgtctct tgaacgccat ttattcgtaa aaaagaactg tgacaagact
    13861 tttgtcacag ttctttttgc gtgcttagcc ttgaaattta actatccata aatacaaata
    13921 ctagggttat tctaacttct tttattgctt gaatcagtcc acaagaaaaa cagcctcttg
    13981 attaaacggc gtttatcttg ttgattctgc ggcaataaaa tcagccagca gcaaaacatg
    14041 aagtgctgtt ttttgctgtc ctcttttatt gcttgaatca gatcacaaga aaaacagcct
    14101 cttgattcac aaatattttt ttcgatattc tcccggcgta atcgattcct tctttttaaa
    14161 gaaacgaata aaattttgcg gatttcgata ttgcaatctt tctgcaatct cttttacgga
    14221 gaggttagtc tctttcaacc atttttttgc tacctctaaa cgatgatttt gaacaaaatc
    14281 accaaatttt tctcctgttt cctttttaaa tacattactt aaatagttag ggttataatg
    14341 caacctatca gcgatcacat ctaaagacag atcacgatca tattctgtgt agacgatatg
    14401 cataatattc tccgacaaat ttttaaattc atgatcagtg attgcttgag agcattctgt
    14461 gattggcaga actaattgtt ctaaaacaag tttttctagt tctttgggat gataattgtt
    14521 cagtgctttt acataaattt gtttcatgtt atcaaagttt tttgaatcta ctcccaataa
    14581 ctgtcctaat tgaacgagtt cattgatcaa gcggaccgaa actacttccc gactcaaagg
    14641 atttttattt tgtgcaaaca atgcatcaat caattcatgt actaaattct tcacttcctg
    14701 atttccagaa cgaatggctt caaacaatcg attttgttct tctatcggat atctaataag
    14761 tgttttttca tgagcagcag gaacgatttc ctgataaaaa ataattgaac ttggaccagt
    14821 atttacacga taatacaggg cttcttttgc ccgatcaacc gattgcttgc tttcattcag
    14881 cgtttcgaac cggttactga tgcctatact gatagttaaa ttcaagtatt cttttacacg
    14941 tttttgaatg agtcggcaat actccatgac ttttttgctt gcttctgcat catctttatc
    15001 cattcgataa atagtggctt gcatttcttc attcaaaacg atcggcagca ttcgattttc
    15061 ctttggcaca atttccgtga tcatgttgtt gatcgctaaa agtagcaaat cacgctcccc
    15121 accgtgacta tcttctaaca gatcgatttg aaccaaagct gtataatagc agtcattttg
    15181 agaactataa ccaaattgct gcaaccgctg atctagttct cgcctttcta ctcgatttct
    15241 aaataaacta agtacaaata gcgtttccag ctgtggcttt tgggtaacta agtgtgcact
    15301 taacgcttct ttttctccta tgatccgact gactgattga gcgaccaaat ctagttcttt
    15361 cccactgaat ccttttgatt taagattcag acgttcctgt atttgagaaa tcggacgggc
    15421 aaatctgtcc gaaaataagt aggaaaaaag accaatgagt cctaccagtg ttaaagacac
    15481 tgcaactagc ccgattctca gattgcggat cattgcgcca attgcactag agtcaacttc
    15541 taatctgtaa atccaattat tataatctga tttcagtact atatacgttt tatctttttc
    15601 tcttatcact ttcagctgat tgtaatctag atccacgtcc gttaatacag ttggttgctc
    15661 tttatttttt actgtctgag tagtaaaaag gttgccaact tcgttttcaa tagaaagtat
    15721 gtcttctcca ctttcaccaa caacttgttc tattgtatgt ttctctatcg tagcaattcc
    15781 caatgcatat ttttcttttt caaacattgg caaagaaatc accatttcga ttcctttgtt
    15841 tttcttttgc caaaataaat tatttttgtt atttatgtac ttctgttgat acttttcaac
    15901 ttcctcttcg gtcagttgac tcaacgatcc attgattact ccccatttac cagccaaact
    15961 gactaaatca taattattat catccataac aatcgtttct ataaaattta gttctttcct
    16021 gatttcagaa taagtggagt aatctgtata tgtcagcgga tgcttgaata tgtccgagaa
    16081 atttttggtc gaaccatacg tagaaaacga atattcaatc gttctaattt tccattcaac
    16141 gttagtttta acttgcctga gcaaattctt tttgtctgtt aaataactcg attcgatcga
    16201 ttcataggta ttctggtaaa tgaataaact aaatcctatg acaagtacgg ctcctaataa
    16261 aaacatcggt aaaaatattt tataaaatac tgtacttttc ttcattttct tcctctcctc
    16321 cttttaaaat aaaaggcttt catttttctg taaaattgat actcatctaa ttaaatgagc
    16381 attccccgct ttcaagaata gcataattaa aaataaaaat ccaagtaatt tttaacgtgt
    16441 gcaatctttt catatcaaag atctattgac ttatcgtagt tatcgtaata tgatgaatgc
    16501 gttaacaaaa agtgaaaaag taaggaaaat gatggaatgg taacgatcaa agatatcgct
    16561 aaagcagctg gcgtttctca tacgacagtt tctcgtgctt tgaataacag cagtttaata
    16621 aaaaatgaaa caaaacaaaa aatacgacaa ctagctaagg aaatgaatta ttcgccaaac
    16681 tatagtgcaa aaggtttagt gaatcaaaaa aaatatctaa tcggactatt tttctcaagt
    16741 ttgcataaag gaacttcatc aaatttccta gcagattcca ttgcaggcat ccattcagta
    16801 ttagacacaa attacagttt atctgttgaa agtatcgatg ttgttgattt aacagaaatc
    16861 aacctgcaac gctacgatgg actgatcgtt atgagtcaaa gtgatgatga tcagcctttc
    16921 atcgactatc tcaaagaaaa agaatttcct ttcgttgttg tcaatcgtca catcaatgat
    16981 ccagcggtta tcaacgtcac tgccgatgat gcggccggtg ttatgcaggc agtagattac
    17041 ggtattggat gcggacatac gaagatcgct tatattggcg gaaagaaaaa ttttcgttcg
    17101 acaaaagaac gggaaaaagg ggtattgaaa agtctaaaaa aagcgagcat ccctgtcaat
    17161 ctagcctatt ttttaacagg agattacagc ttagaaagcg gcctccaaaa catggaatac
    17221 ctattatcac tttctgacct gcctactctg gttttttgcg gcaacgacga catagcgatt
    17281 ggtgcattga gagctgtaca tttagctggc ctccgtgttc cccagaacat ttctctgatc
    17341 gggttcgatg attctccagt cgtctcctat ctcaatccgc cgcttaccac cgtacgtaag
    17401 cctttgaaag aaatgtgtca agaaggaaca aagcttttac tagatttgat cgaaggcagg
    17461 acgatcgaac aatctaaaat tgagctctcc accttgttga tccttcgtga gtcgatcaat
    17521 tacttgtaaa ctacaagtaa ttttatataa aaatgttaac gtgtgcataa cacagaaagg
    17581 aagtttatat gaaaaaactg acaaaagaat tagtgaaaaa aaacgaagca cctgtaaaag
    17641 ttcttcagtt tggtgaaggc aattttatgc gtggatttat tgattggcag attcagcagc
    17701 tgaataacca acaattgttt aaaggtaatg ttgcaatcat tcaaccttta gaacaaggtc
    17761 ttggaaatat gatgaaccag caagataatt tatatacggt cattttacaa ggactcagca
    17821 atggcgaaat cgttgatact tccgagatta tcaccgtagt agaacaaatg atcaatcctt
    17881 atgatgaatg ggatgcttat ctatctctag cagaaaatga cgacttggcc tatatcgtct
    17941 ccaatacaac agaggcagga atccaattcg tggagactga taatttaaca gatactcccc
    18001 cacagagctt cccgggcaaa ctgacagcct ttttataccg acgtttcaaa ttaaacaaag
    18061 ctggctttac catcattcct tgcgaactga ttgacagaaa cggcgaacgt ctaaaagaaa
    18121 tcattttacg ctacgcagaa aaatgggatt tagaacctgc ttttgttgag tggttagaaa
    18181 aagaaaatgt tttctgttgt agtttagttg atcgcatcgt cccaggttat cctcgcgaag
    18241 atgcaggtgt tttcaatcaa cggcataact atgaagatca attgatggtc aaagcagaac
    18301 cattcatgct ttgggtgatc gaagggccta aagaattgga gaatcaacta ccattcaaac
    18361 aggctggctt gaatgtcatc atcacagatg atatgactcc ttatcgtgaa cgtaaggtgc
    18421 atttgcttaa tggaccgcat acagcgatgg tccctcttgc tttgttggcg gaattggaaa
    18481 ctgtagaaga agtaatgaaa gatcctttat tctccgcata tgttgatcag ttattcaatc
    18541 tagaattgat tcctatgctt tctttaccta aagatgaatt agccatttat gctgaccaaa
    18601 tcaaagaacg tttcttgaat ccttttgccc atcacaaatt agaagcgatt tcattaaata
    18661 gtgtttcaaa gttcagcacc cgtctgcttc cagtgttcaa gaagtatatc gaagaacaaa
    18721 atcaggtacc accgttaatc actgtttcac tagctgcgct acttcttatg tatcgaggcg
    18781 atcaagtaaa gccacatgat gatgaaaaga cgataagcga atttactgat gcttggtctg
    18841 ataatggaac agctattcct cgattattgc aaaacgctgc gctttgggga gaagatttgt
    18901 ctcaaatacc gaatgtgaca gatacagttc aagaaatagc tgcaaagatc gatcaaaaag
    18961 gtgtccggtc agtattacaa gaaatgaaag gaacgatggt ccatgcttga aaccctgcaa
    19021 ccaacaatga aattaaatcg acgagacagt gtggtcgtcg cattaacccc tattccaaaa
    19081 caaacacaac tgacgattga tcagcaaacg atcaccactc ttgaagatat cccgcaaggt
    19141 cataagattg cattgggtga tttgaaagct ggagacaacg tgatcaaata tggctatcca
    19201 atcggtcatg tgacgacaga cgtaactgcc ggtcaatggc tgcacactca taatgtaaaa
    19261 accaatcttt ctggtgaatt ggattatcga tatgaaaaag atgtccatcc aagtcattac
    19321 ctttttgaga accgaacatt tcaaggttac ttgcgaaaaa atggaaaagt agggattcgt
    19381 aatgatttgt ttttagtacc taccgttggg tgtgtgaatg gcattgctga actgatcgtc
    19441 aaacagttca aggaaaaaca tccagatctg ggacagtttg accatattac gattttaaag
    19501 catccttatg gctgttcgca gcttggaaaa gatcatcaaa atactcgaga aattttagcg
    19561 gacgcagtaa atcatcccaa tgccggagga gttttagtat ttggattagg ttgtgagaac
    19621 aatacagttc ctgaattcaa aaaaatttta ggtgaatatg atgaagaacg agtgaaattt
    19681 ctagtggctc aagatgttta cgatgagatc gaacaaggtg tggctctatt agaagagctt
    19741 ttaacagcgg cggaaaatga ccagcgcata tcagtcccgc tctctaagtt gaatgtcggt
    19801 ttgaaatgcg gcggttctga tggtctatcg ggaataactg ctaatccttt acttggtgca
    19861 ttttctgact acttgattgc tcaaggaggc agcacgatct taacagaagt gccagaaatg
    19921 tttggcgcag aacaagtatt gatggcacga gcggaaaatg aagaagtttt tgactcaatc
    19981 gttgacttga tcaatgactt caaacagtat ttcttgtctt acggggaacc agtttacgaa
    20041 aacccatctc ctggtaataa agcaggtggg atcactacat tagaagataa gtctttaggc
    20101 tgcacgcaaa aatcaggaag ctctcctgtc gttgatgtgc tacaatatgg cgaaaaaatc
    20161 agaaaaccag ggcttagttt attgcaagct cccgggaatg atcttgtagc tgcctctgct
    20221 cttgcttcat ccgattgcca gttggtcttg tttaccacag gaagagggac tccgtttggc
    20281 tcatatgtcc caacggtcaa ggtatctacg aatacaactc tttttgaacg caaaggtcat
    20341 tggatggatt ttaatgcagg cgtcttatta gaacaaccaa tggaagtaat cttagaatcg
    20401 tttgttcaaa aaatcatcgc tgtagctagt ggagaagaaa cgaaaaatga acaaaatgac
    20461 gttcgagaaa ttgccatttt taaaaacgga gtaacacttt gattttcata aaacagtata
    20521 aaaagaaaga aggaagattt atgtttttat ctgatgattt tttattaaaa gacgattggg
    20581 cgaaaaagct ttaccattcc tacgcaaaaa acatgcccat tattgattat cactgtcact
    20641 tagatccaaa agaaatttac gaaaacaaca atttcagcaa tctgacagaa gcttggttag
    20701 gaggcgatca ttacaaatgg cgcttgatgc gagcttgcgg cgtgcctgaa gaaaaaatca
    20761 caggaaatgc ttctgatttt gaaaaatttt tagcttggtg tcaaaccgta ccaaaaatta
    20821 tcggaaatcc gctttacagt tggtcacatc ttgaattgaa gcgtttcttc ggtattgact
    20881 tgttgataaa tgaagaaaat gcagagaaaa tttggacaca agcaaatgaa attttggcag
    20941 ctcctgattt tcgccgtcgg gaaatcgcaa aaaaatcgaa tgtagaagtg atttgtacaa
    21001 cagatgatcc cgcagacgac ttgcactatc atcagttgct tgctcatgaa gaaccagatt
    21061 tgaaggttct accttcattc cgtccagata aagcactcaa tattgaaaaa gaaggattta
    21121 atgcatgggt cacactactg gaagaagcag ctgaccaaac gatcaccacc tatcaagaac
    21181 tgatagaagt cttagggcag cggatagaat acttccatca acatggatgt cgtgtttccg
    21241 accacgcttt agacatctta cgctataaag aagcggatga aacagtatta gaagagattt
    21301 ttcaaaaagc acgagctaac aaactattat cttcagatga aatcgatgct tatcttacag
    21361 aaacactgat acatttgacc cacttctatc attctcataa ttggacgatg cagctgcaca
    21421 tccatgctta tcgtaactgt aatacacaaa tgttggaaaa attagggccc gataccggct
    21481 atgatggaat gaatgatctt tctttgacta ttcctctgca aaaattattg aaccgtgcag
    21541 aagaaacgga tcagttgcca aagacgatcc tttattcatt gaatccgaat gactatcctg
    21601 cgattttagc tttgatgggc tgtttccaaa aagaacagaa tggaaaactg cagttaggtt
    21661 ctggatggtg gtacaacgat actcgagctg gtatgcgcga tcaattgaca caatttgctg
    21721 atggtagtgc tttggggaat tttgtcggca tgctgacaga ttcaagaagt ttcctgtcct
    21781 acactagaca tgaatatttc cgtcgtgttc tttgtgaatt tttaggcgaa atggtcatgc
    21841 gaggagaagc acctgaagat gaacaacttt taggaagtct agttcaagcg attagttata
    21901 caaatgctaa aaattacttt ggcttttttg cctaattgat taatagtaac agtaacgaat
    21961 caaaaacagg atagtgaaat aacggaatcc gtttatccac gttttagaga agaagacgga
    22021 ccaaatt
//
LOCUS       DAZKNV010000046        21937 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000046 DAZKNV010000000
VERSION     DAZKNV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.046"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(40..483)
                     /locus_tag="ACG8M1_001951"
     CDS             complement(40..483)
                     /locus_tag="ACG8M1_001951"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422633.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(499..1659)
                     /locus_tag="ACG8M1_001952"
     CDS             complement(499..1659)
                     /locus_tag="ACG8M1_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0422634.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            2166..3866
                     /locus_tag="ACG8M1_001953"
     CDS             2166..3866
                     /locus_tag="ACG8M1_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422635.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(3968..4801)
                     /locus_tag="ACG8M1_001954"
     CDS             complement(3968..4801)
                     /locus_tag="ACG8M1_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFQ0422636.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(5105..7270)
                     /locus_tag="ACG8M1_001955"
     CDS             complement(5105..7270)
                     /locus_tag="ACG8M1_001955"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFQ0422637.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKNPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7530..9824
                     /locus_tag="ACG8M1_001956"
     CDS             7530..9824
                     /locus_tag="ACG8M1_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFQ0422638.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            9817..10482
                     /gene="pgmB"
                     /locus_tag="ACG8M1_001957"
     CDS             9817..10482
                     /gene="pgmB"
                     /locus_tag="ACG8M1_001957"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFQ0422639.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            10475..11482
                     /locus_tag="ACG8M1_001958"
     CDS             10475..11482
                     /locus_tag="ACG8M1_001958"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0422640.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            11504..12523
                     /locus_tag="ACG8M1_001959"
     CDS             11504..12523
                     /locus_tag="ACG8M1_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0422641.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(12804..14171)
                     /gene="nhaC"
                     /locus_tag="ACG8M1_001960"
     CDS             complement(12804..14171)
                     /gene="nhaC"
                     /locus_tag="ACG8M1_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFQ0422642.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(14280..15701)
                     /gene="tyrP"
                     /locus_tag="ACG8M1_001961"
     CDS             complement(14280..15701)
                     /gene="tyrP"
                     /locus_tag="ACG8M1_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFQ0422643.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(15944..17821)
                     /gene="tdc"
                     /locus_tag="ACG8M1_001962"
     CDS             complement(15944..17821)
                     /gene="tdc"
                     /locus_tag="ACG8M1_001962"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFQ0422644.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRNVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(18112..19368)
                     /gene="tyrS"
                     /locus_tag="ACG8M1_001963"
     CDS             complement(18112..19368)
                     /gene="tyrS"
                     /locus_tag="ACG8M1_001963"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFQ0422645.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(19480..19685)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19948..21249
                     /locus_tag="ACG8M1_001964"
     CDS             19948..21249
                     /locus_tag="ACG8M1_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFQ0422646.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(21318..21917)
                     /locus_tag="ACG8M1_001965"
     CDS             complement(21318..21917)
                     /locus_tag="ACG8M1_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0422647.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         6610 a         4588 c         3922 g         6817 t
ORIGIN      
        1 aaaaattagg ctgggagcat tatttcgtta ttctgttcat caaaaatcag cgttttgatt
       61 ccatttcatc acaagttcct cctcatttac tgcttcatct ttttgctgtg tttgaattgt
      121 aaaaccttgt gaaagataga aatgaatagc tgattgattt ttttgataga ctgtcaaagt
      181 cagtgtttta ttggtttctt ttattttttt cattagttgc gtaccgattc tttgttgccg
      241 gtattccctt ttcacaaaga ttcctgcgat aaactgatca atcaccccag caaaaccaat
      301 aatttcttga tctatttctg ctaagtaaat cactgcatct ggtaaagctt tcctaacaga
      361 ttctacttga ttctcccaat aagttgatgg aatgaattca tgagaatcca agttagcatg
      421 cagccaaatc gatagaacag attccagttc tttggcagac aattttgttg ttgtgcggat
      481 cattttttct ctccttactt attcattgat tttaaaataa aaaccatttt tttgaagctc
      541 ttttacaagt tttcgcccct caaaaaagta tatcttctct tgttttactt ttctaatacc
      601 aaaagaaaca gcaactttag gatcatcagc tgaaacgatt cgataagttc caccaggcaa
      661 ttgatccagc ttgactttcc catgatggtc gctttgtact gaaaacggca caccatttct
      721 agtaagtgtt tttttcttat gtttcaaaat gaatgaacta ccatttaccg gtttccctga
      781 cgaatcacta ataataaatg aaaaatcaag cactttttta cttaatctat actgatagat
      841 tagtcgtccg ataaacacta acagtatgac tacagctatt atcgttcctg caagaataaa
      901 ccattgccgc atggttcttt cctgatttcc ttttccttct tcttttttta ccgattcgtt
      961 ataaggaatc cgatgtcctg tcactagcaa acgatgcgtg ttgatcatat acggcgtaca
     1021 tgtaagcaag gtaactaagt cttctccttc tgaaatcgtt agaacagacg tgtcatctgg
     1081 cagtaccact tgtatatttt taacttgata agccaatttc tcccccaaaa cagtcaaaat
     1141 aaacgtgtct ccgttttcta aacgatctaa ttcggtaaat aaccgtcgat taggtaaacc
     1201 gctgtgagca gagatcactg aatgcgtcga atttccacca agcgggaaag aggttccttg
     1261 caagacgcct gctccatttt caaggatcct accattgagc cgatcataaa gtgaaatatt
     1321 taattggatc ttaggtatat tgatacttcc gatcagccat tcctctaatt ggctggatgt
     1381 tgtactttca tttctgttct tttcattgaa aggatcagta ccaggattga atccttggtc
     1441 agttaatcgt tggtttttct cctccatttt ctttcgctgc acttcaattt cagctgcggt
     1501 ccgtttttgt acttgttcga tacgtttttg atcaataaaa ctatttaaag aatccacata
     1561 aaatggatat aaagcgatca gtaaccctac gacgatacat attaataaaa acaaacgaaa
     1621 caaaagtcga cgagactgtt tttgcttact ctgcttcaca tgtgtcctcc cttgcaagtt
     1681 tttttgttct ttcttttatt atatgggttc aggaaaaaaa tagaaaatga aagccgatga
     1741 ggttgtgaaa aagctgtcct gcatcaagta ataagtacag cccaaaaaaa tagctactca
     1801 tattttttgt tgggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga
     1861 agaggttgtg aaaactgcgt tatgctttga gtaataagag cgctagtcag aaaatagctt
     1921 ctcatatttt ctaggctagt gagcttatta ccgagaagca gctgattgaa caccgtttac
     1981 cgagaggtca tgaaaaagct actttgtttc gagtattaag aaaaattctg tttcaaaaca
     2041 aggagatgca acaaaactta tgtcgcatcc tctctcctta gaactttcac ttatgttttt
     2101 cttgtaaaat tcataaatat tttcatgaat tttctaattt cttgcctacc tctcgcatag
     2161 gatatatgat gaatttatct aaagtttgca aaggagttcg acaattgaaa aaatatggcc
     2221 catttttagc aatttttttc attgctttgg catttctcat gcctcattta ttcacacata
     2281 aactaatttt gggtgctgat gccccattcc attacaatcg gttctatgat gccgcgcaac
     2341 aaattaaata tggggatttc cattattttc cttcccttta tggattccag caaagtggca
     2401 ggatcgtgaa tgccgtttac ggcccatttt tcgcttattt acaaggattg atcgtgttgc
     2461 ttgcaggtag ctggtttcat tatcagattc tttcaaattt cattctttat cttatttcag
     2521 gattttctat gctgatttta ctgagatatg tcaatgttcg aaattgggta agtgtaccag
     2581 tagccgtttt attcatgagt acgtattcta ttcaatactg gtctatcaac caaggattca
     2641 ctagctgggg gacttgtttt tatcctttat gtatgatccc tattgctgat ttcgtccttc
     2701 ataaaaagtt ccctgttatc aaagtcgctg tctcagtggg acttatgaca cagatccatt
     2761 tactgtcttc gatcatgtta gctttgatgt atatcccttt ttatctttat tactttttta
     2821 accagactga aaaaggaaaa gcactgcttc aactgattaa gtcggtcttg ctttattttg
     2881 ttctgacagc aaatatttgg gcaggattag ctattgttta cagtgggaat aagattcttc
     2941 ctccctttgt taacagagaa atgagtcaaa aggcgataga tctggatggc agttattggc
     3001 tccattaccc taaggccttt cctatattga tattatcagg ttttttgctt tttattttct
     3061 ttcaacaaaa gaacacctta ttccaaaaaa tcgtgttgta cacaagtctt gttttctttt
     3121 ttctttctac tagcttgatt ccatggacga cattgatcga aaaaaatgtg ccttttatta
     3181 gtttgatcca gtttccattt cgatttttcg tgccatttac gctattgctt ctactttacc
     3241 ttgccctttc actgaaccag tggtctgaac aaaagtggtt ccgtctttta agtatatttg
     3301 gcattcttat tttttcagca cagacgatcc agaacttata ccagcatctg gaaaagtggg
     3361 aaaatgaaac atttgtcagt cgacatactt atctattcga tacgccggaa gaagcaagga
     3421 aaacattctt cagcaaagat atgtctacca gcttgttcgt tttccaaaaa accacacctg
     3481 actatctgcc aatctataag gagacaaaag acaataaata cgaccggtat aacgaagaaa
     3541 tactagaaaa cgaaacaact tttataaaaa cacatccagg cggtcttttg acaatcaagt
     3601 ggaaaaacac tggggacaaa actgttcata tccctgttat cgtctacgat cggactgtgc
     3661 tacagcaaaa tggaaaaaca ttgactgatt atgaagtaac agatatcggg accccaatcg
     3721 tgaagcagca aaaaggaatc aacgagctca cgcttcatta tcaaacgcca atctatttct
     3781 atttcattct ttctcttact ttgattggct ggtttacctt gctatgttta tttatttatc
     3841 atagatacaa gcttttacgt gcttaggcaa aagggataaa tacatccgat caaaaaactc
     3901 tccaaacggt ataatcgttt ggagagtttt attttaatca gtttttttat gttatatgtt
     3961 atatttttta ttcgttcaca tctaattcga tttccacccc gtagtgatca ctgatgattg
     4021 gactatcgat cccatcaaaa atccgttgat attttttaac ctgcattcct tcagggacga
     4081 aaataaaatc tatacgcaat ttttctgtat tttgttccca accatctatt ttcttttcca
     4141 cagtagctgc ttttcctttt tcattcgcga caacatacga atcttgaaga agaaggcaac
     4201 tttctcttac agtataataa ccttgagagt ctactggatt attgaaatca cctaggaaaa
     4261 aaagtggtac gcgagtttcc aaaaagtagt tttccaagtt tttccactca aaataaaagc
     4321 cacttttttt atctgtccac caagaaaagt ggcagctcga gacaaaaatg tcctgatcat
     4381 ctatctttgt tttcccaatc aagatcttgc gtgtctgata atcttctttc ttttgaaatt
     4441 gggagacggt aaggacctga ctttccaatg tttttttcgt aagcagtgca tttccttctt
     4501 catatttatc ataaccgatg tggctcattt cccaactcca aaaatactct tttccgtgtt
     4561 cctttaaaag ctgaactaaa cggtaggcaa aattatcttt acggataggt acttgattct
     4621 ttaccggaca gaacttcatt agcttcgcag gttctacttc ttcagattcc agtaattggt
     4681 tgatttcttg taaagcaatc acttcataat cttctaacag gatcttatct gctaattctt
     4741 gcaatttttt ctctggttct ggctcaagcc agctatgcgt gttgagtgtc atgaatttca
     4801 ttggttttct ccttgtcttc atttcgaaac aaaagggttg tgacaaaatt tttgtcacaa
     4861 cctctccagc aaatagtgtt ctcctgctaa ctcctcagta ataagctcaa tggaccagga
     4921 gctatttttt gtttggctgt ttttatcact tggtgcaggg cagctttttc acgacctctc
     4981 cactaaacag tattcaaact gctgcttctc ggtaataagc ccaaccaaac gaaaaatagg
     5041 aggagctatt tttgtttggc tgttcttatg acttgatgca ggacagcttt ttcacaacct
     5101 ctccttacat tttaatggag ccgatcactt taccagctgt cactgtacct aattgcttga
     5161 tcactacttc ttctacttta tcgtttgtaa atacgatcat gatcgttgga tctttttctt
     5221 cgttttggat cacatcaaga tccatctcag ctaatttcgt tcctgttcct acttcttggc
     5281 cttctttgac agcaatctca aaagctggct gattcatttg gactgtatcg attcccatat
     5341 ggatcaaaac ttcgatacca tctttcgttt ccagcccaat tgcatgtttg ctagggaaaa
     5401 tacttgtcac ttttccagcg atcggcgcaa caacttctct tgatgttgga ataacagcaa
     5461 agccgtcacc catcattttt tgtgagaata ccggattttt tacttcagat aaaggaatca
     5521 cttctccaga agctgcggaa actagttctt gttctatacc taagtattgc ttactacctg
     5581 cttgtccatt tcctgtagaa accatttctg gctctggaat ctctgctcct gattgcagca
     5641 gatcttcgat atctgatttc aagacatctg cttttggtcc ataaactgct tggactccat
     5701 tgtctttgac gatcaatccc atcgcccctg ctcgtttcca ggcttcttca gtccctactt
     5761 tttctcgatc atttacactt acgcgtaacc gagtcataca agcatcgaca tctttgatat
     5821 tttcttttcc tcccagcaaa tgaatgatct ggaccacttg ctgatctgct gttcctgttc
     5881 cgctgttaga tacaacggtt tcttcactgt cattgtcgta atttccgtta cgtcccggtg
     5941 tagcaaagtt gaattttttg atcaagaaat ttgctaagaa atacgtaaca acaccaaaag
     6001 cgatcacaca caacacgaag ttgataagat ctccacctag acccgctttg atagctaacg
     6061 gtgtccgagt cagcaattcg atattcccaa atgaatggac ccgcaatggc aagatatctg
     6121 ccatcgcaaa tgcagcccct tggatcactg aataaatgac atataatggc acagcagcaa
     6181 acataaacat gaactccaat ggttctgtta cacctgttag aaagacagcc aacgctgctg
     6241 aaaaatacat tgatttatat cttgctttct tatcaggatc gacattacga tacatcgcaa
     6301 aagccattcc catcaagata cctgaagaac caatcatttg tcctactttg aaacgagccg
     6361 gcgtccagtt atgcaacaca aactcatatt gcgacatatc ccctgcacct ttaagattca
     6421 ctaaatcagt ggcccaagcc aaccataacg gatcttgccc aaatacttgt gtccccgcct
     6481 gtgcgcctga taaaatctca tacgatccgc caagctgtgt atagttgata ggaatcgtca
     6541 gcatatgatg caatccaaat ggcaatagta aacgttctaa tgttccaaat aaaaacggtg
     6601 ctagaatcgg tgcgctttct tgtgattctg caatccataa accaaaatta ttgattccag
     6661 cctgtacgtt tggccacacc acagcaagaa tcaatgccac gattgttgac cataagataa
     6721 caacaaacgg aacaaagcgc tttccattga aaaatgacaa agcatccggc aattttctat
     6781 aattatagta cttattataa gccattgccc cgacaaatcc agcgatgatc cctacgaata
     6841 ctcccatatt caaagctggt gcttccaata cacttgtaaa aaatccttta accatgatct
     6901 tcgtaccgaa cagagtgtgg gtaaatgcat cttcattcgc aagcatgtca cttgtgacac
     6961 caaagatagc cccagtgatc cgattgatta aaataaatga gatcccagct gcaaatgctc
     7021 cgcctgctct ttcttttgcc caacttcctc ctattgctaa agcaaataaa atatgaagat
     7081 taccaataat tgcccaacca atattttcaa ttactccgcc cgttgtgaca agcggcgtcc
     7141 aatcaggatt gatcaaggga attgatttcc ctatactgat catcaaccca gctgccggca
     7201 taactgctac cacaaccatt aaagcctttc caaatttttg ccaaaactca aaactaaata
     7261 tctttttcat tccgtttagc tcctttacgc aatcggtttc gttaaacgta ttatagcgtg
     7321 cgttttcttt tttgtaaatg ctttattttt tatttttctg tctataccat tctataaaac
     7381 ctataatacg tgtgttccct tctataattt tctcctaaaa atttattttt ttaagctttt
     7441 ttctatgaaa tattttcttt tgtctattga cttgtgcaat cggttgcgtt tattatgaac
     7501 gtataaaaca gctcattagg aggagaaaaa tgaaacagat caaacgacta tttgctattg
     7561 atccatggaa aatcagcacg acacaattag ataaaaaaaa tcttcgactg caagaatctt
     7621 taacaagtat tggaaacggt tatatgggga tgcgcgggaa ctttgaagaa acttactcag
     7681 gggaccacca tcaaggtact tatttggcgg gtgtctggta tcccgataag acacgtgtcg
     7741 gctggtggaa aaatggttat ccagaatact ttggaaaagt gatcaacgcc ttgaacttta
     7801 tcgcgataga tatttcgatc aacgatcagc tgatcgactt ggcttctttg gaaccagaag
     7861 acttttactg ggaattagat atgaaaaatg gtgtattatc tcgtacattc acaatcacta
     7921 cttctactaa taaagtacgc atttccttcg aacgttttct gagcattgtc aaaaaagaat
     7981 cagcttatat ctatttaact atagaaatgc ttgaaggtag cggaacagtc aaactcgtat
     8041 caaaattgga tggaaatgtt caaaacgaag acagcaacta tgatgaacat ttttggaatg
     8101 agattgatcg tggaactata gaagaaatcg gctatttgac gactaaaact attccaaaca
     8161 actttgggat tgaacaattt actgttactg cagcaatgcg ccatttcgtt aatggaaaat
     8221 cagtcatccc tgactatcac gaagatactt tagcattaca tggttgcttg tctgcagaat
     8281 tatctcaagg tgagacatgg tcagtggaaa aagaaattat cgttcttact agtagagata
     8341 ttccagaagc gcagcaagca gaaaaagctg tctcagaatt aacgaaccag acaaacaatt
     8401 atatccaagc aaaagaagag caaacagcgg cttgggcaga acgatggaag cttgccgatg
     8461 tggtcatcga aggagacgaa gaagcacaac aaggtattcg attcaatttg ttccaactat
     8521 tctctactta ctacggcgaa gatgaacgat tgaatatcgg ccccaaagga ttcacaggag
     8581 aaaaatacgg cggagccact tactgggata cagaagcgta tgctgtccct ctttatcttg
     8641 ctttagccaa acctgaagta actaagaatc tgctgaaata tcggcataat caactgccgc
     8701 aagcaatcca caacgctcag caacaaggat taaaaggcgc gctttatcct atggtcacct
     8761 tcactggtgt cgaatgccat aacgagtggg aaatcacatt cgaggagatt caccgaaatg
     8821 gcgcgattgc ctatgcaatc tacaattata cgaattacac cggcgatacg gaatatttga
     8881 aaaatgaagg actggaagtt ttagcagaaa tcgcacgctt ctgggcagac cgtgtccatt
     8941 tttcaaaacg agcaaataaa tacatgatcc acggtgtgac cggcccaaac gaatatgaga
     9001 acaatatcaa taacaattgg tatacaaata cgatcgcagc ttgggtcttg cgttacacgc
     9061 gagaaaatta tttaacttat caaaaagaag ctgctatcac tatcagcgaa gaagaactag
     9121 ccaaatggaa agatatcgca gagaacatgt acttcccagt tgacgaagaa ttaggaatct
     9181 ttgtccagca tgacacattc ttagataaag atctcatgcc tgtatccgat attcccacaa
     9241 gcgatcttcc tctgaatcag cattggtctt gggacaaaat ccttagatct tgcttcatca
     9301 agcaggcaga tgtactacag gggatttatt tcttcaatga tacttttaca aaagaagaaa
     9361 agcaaaaaaa ctttgatttc tatgaaccaa tgactgtcca tgagtcttcc ctttcgccaa
     9421 gtatccattc gattttagca gcagaattag gaatggaaag caaagctgta gaaatgtacc
     9481 agcgaacagc tcgcttggat ttggataatt acaataacga cacagaagac ggcttgcaca
     9541 tcacttccat gactggtagc tggttgtcga ttgtccaagg atttgctcaa atgaaaactg
     9601 cccatgatca gttgagattc gcaccatttc tgccaaaaac ttggaaagct tattctttcc
     9661 atatcaatta tcgcggacgt ttattgttca tctcagtcac agatgaacaa gttactttcg
     9721 agttattaga aggttctcct ctagaaattt acgtctatga acagtcttat tctttagcgg
     9781 atcgtctaga aataacgcta agaaaggagg aagcaaatgt ttaaaggggt attgtttgat
     9841 ttagacggtg tcattaccga tactgctgaa ttccattatc gtgcttggcg aaagcttggt
     9901 caggaaatcg gcattacgat cgaccacaca ttcaacgaac agctaaaagg cgtcagccga
     9961 gaagactcac tctctttgct tttagcttat ggcggaaaag aacactcttt ttcaaaggaa
    10021 gaatttgcag aattagcgaa aagaaaaaac gattattatt tagagatgat ccagacgatc
    10081 gaaccaaaag atgtcttccc cggggtcgtg cctttactgg attctttaaa agaagaaaaa
    10141 atcaagattg ctcttgcttc tgcaagtaaa aacgggccat tcctacttga aaaaatgggt
    10201 cttacacctt actttgatgc tattgccgac ccggcagaag caacaaacgg aaaacctgcg
    10261 ccagatatct tcctccttgc agcaaaagct gtcggactaa aagcagaaga atgtatcggg
    10321 atcgaagacg cgcaagccgg tatccaagcc atcctctcaa gtggcgctca accaattggc
    10381 gtgggacgtg ctgaagacct tggagaggag atcccgcttg tccctgatac gacttttctt
    10441 acgatcgatt acttgaaaga aaagtggcat gaccatggat aatccagaga tctccgtcgt
    10501 accagttcca gagactgaaa taaagaaaat cacattgaag aacgactact tagaagtcgt
    10561 tcttctcaat tacggtgccc gcctgcacca aatcttcgca ccagacaaag aaggaaaatc
    10621 agaaaatgtt ttattgtctt acgatcgttt cgaagatgtt ctaacagaca aaagcttttt
    10681 tggagcaact gtcggacctg tagccggaag gatccgggat gcttcttggg gtgagcatag
    10741 attggagaaa aactgcggat cacaccatat ccacggtggc acgaaaggct ggtctttcca
    10801 attttgggaa gtagaagttt tcaaaactcc atcatcaata ggtgtggtct tttacttaaa
    10861 agatgaattt tctacctatc caggaccaat cactgctacg atcacttacc gtttaacaaa
    10921 aaacgaatta gagatgacaa cctctgctag tagccttgtt gaaaccatct gcaatccgac
    10981 caaccatgcc tacttcaacc tttcaggaaa tggaacaaga gacatctatg aacatcagtt
    11041 aacggtcttt ttagatggtg tgcttgaatt agatcaagaa aaactgccta ctggaaattg
    11101 gacaaaaaaa gaaaaactgc caatcgactt tagaaaatcc ccaacactgc aagagatcct
    11161 tgcatgttat ccagatggac tagatgatgt atttcttttg catcatccta ggctttccaa
    11221 aacttcctta caattattcg agaagcattc tggtcgccaa atgactatag caacttctaa
    11281 taaaagtatg gtattatttt ctacgactgg attcgaagct gatttctctg tcaatggaaa
    11341 acagatgcat tcaaactacg gattagcaat cgaaccgcaa gaaatccctg atatcgttca
    11401 tttccccaaa tttggatcga tcaacctcca tcctggtcaa gaacggatca gtcagacgat
    11461 ttatcggttc tctgcacaat aacaagagaa aggtgttttt atcatggcta ttaccgtaaa
    11521 agatgtggcg aaaaaagccg gtgttgccac ctcgaccgtc tctcgtgtca tcaacgatca
    11581 tcctagtatt tccgagacaa caaagaagaa agtccgaaaa attatggatg aactaggtta
    11641 tgttcctaac atgactgccc gcaatctagg aaaacgcatt tccagtgcca tcggcgtaat
    11701 cttaccccct cttgattcaa aagagcggat cggtaaccca ttttatcttg agatcatgga
    11761 agcaatcaac gaagaagcgc ggaattatga tatgactaca gcaatcgcta ctgctaaaaa
    11821 ttttgaattg ctgttagaga acgtccagcg tatgcattta caaaaacaag tagatggttt
    11881 tattctagtg tattcagata gtcaagatac tgtcattgat tatttatacc aaaaccacat
    11941 ccctttcact ttgatcggac agccttatca tcatgagaac gaaatcgttt atgtagataa
    12001 tgataaccag cttctaggta aacaagcaac agaatttttg atccagaatg gacataagaa
    12061 tatcctgttt gtgacaaaca cgactcatga aagtttgtat ttcgaacgat atttcggtta
    12121 tcaaaaagca atgatgatgg ctggtcttcc tgcgttatcc agtgtagtac tagagcatcc
    12181 ggaggattat ctgtcctttg agaaaacgtt gaaagaaaac gaagccacag cattggtggt
    12241 cattgacgat atcttcgccc ttcgcacgat gcagttggcg caaatgtatg gctatgtcat
    12301 tccagagaca ctctccgtca ttagcttcaa caactcgatc ttctcaacat taacacaccc
    12361 ttaccttaca agtatcgata tcgatatctc cgaattagga cgtgtcgcta tgcaaaagct
    12421 gcgcgaattg atccatgaag aattgagcag tggcgtacgt ttggtcatcc ctcatcgctt
    12481 gatcaaaaga gagacagtcg ttcctttaga aaacccatac taaatagctg actcactaaa
    12541 tacgctgacc atttatccta tggtcagctt tttatgtaaa agaagatact acttctaaca
    12601 cattgtttat ctgtaaaaaa gagcgtggga caaaagtaaa gaacactttt gtctcacgct
    12661 ctaaacacgt ataaacggcg gaagcagaag caactccttc ggaaataagc tgaaattcac
    12721 aaaaatttaa aaagcaattt tcttgagttt cttcttattt cttggagtta aacgcttctg
    12781 tcccagcctc ttttttcctt ccttcaattt tttacacgtc gacgattcaa taaaaaaccg
    12841 cctaatattg taaagacagg tgcaagaatc gagaaaaagg cgaatggcaa gtaatgcaac
    12901 gcgctaactt tcatcgttcc cataatgaat gtgccgctga ctccccacgg tacgagagaa
    12961 ttgacggtcg cacctgaatc cgctagtgtt cgtgtcaaat aggtttttga taagccaacg
    13021 tcatcaaaag aacgcttgaa tgtttctcct ggaagaatga tggacagata ctgttctcca
    13081 acgatcagat tgattccgat acagctcaag gcagtaaacc cgactaaacg agaaggtcgg
    13141 tccatctttt cttttaattc ttgaacgatg gtatcaacga tcagatattt gatcagtaac
    13201 ccacctaatg ccaatgcaag taaaatcaaa ctagcagaac ctaacatact catgatcccg
    13261 cctcgagaaa gcagttcatc tagctttgga tcaggtgtat ttgcgacata accattcatc
    13321 aagatgtctg ctgcttttcc gaccgtcaaa cttttctcat ggataaaaga aagaacgaga
    13381 gcagctgtcg atcccgctag taatgtaggg atagccggaa tttttttgat tgccccccca
    13441 aataaaataa ctagtggaat caatgtccaa ggagagatcc aaaagctcgc tttcatgttt
    13501 tggatcattt cattgatact agctagatcg gctgaatgac tgttatgtcc taatatcgta
    13561 taaaaaatca acgaaaggac gaatgctggg aaatccgtat aacgcatacc agcgatatgt
    13621 tcgaatagat taactcctcc aatacccgct gccaagttgg tcgtatctga taaaggcgag
    13681 cagttattcc ctaaaaaggc accggaaacg actgcgcctg tagtcattgc atcattgaat
    13741 ccaagtaaat gaccgatccc caaaaaagca attccaatcg tcgaaatcgt tgtaaatgaa
    13801 ctgccgacag tcactccgac aattgcacaa acaagaaatg ctgtcggtaa aaagaaacgc
    13861 acagaaacaa gtttaaatcc ataaaccata atcgtaggga tggttccaga taaaatccat
    13921 gaagcaacta agacaccaat caaaagaaaa atcaggattg gaatgatccc tggagtgatt
    13981 cctttgatga tcccgtcatg gatctcatcc catgtgaact ttttaaatct gccataaaac
    14041 aacaaacaca tgaaagctgc aaggatcggg atatgtggcg agagctggaa tccgatgatc
    14101 agtactccta ggagtgccaa caacacgatc aatacagcga tactttcttt taaagaaata
    14161 tttttattca tcgtcgatct cctatttcaa atgaaaaggc cctgccatga aaaaactatt
    14221 cacttggcag gacctcctac taaatcagcg acaaaacgtc ggctgaaaga cttatttttt
    14281 tatttttctt ctaaactttt ttctacctca atcccccaag aatctttctt gaagtgattg
    14341 atgatcaatg gaataacgaa catgaccact gtgatagctg ctactaataa tgcatcactc
    14401 aatgtcgctg tacctaatgt agcaaatacg acaacgatga tagagaagat cagcatgcag
    14461 ctgactaccc aagctaatcc gtttccgttt ttaccaattc ggtaaggacg ttcgaattct
    14521 ggatgtttct tacgcatttt aagcaatgaa acagcaatca aaatgtacac gatacaataa
    14581 ataacagttg tagcatttgt aagtgtcaag aatacagcac ttacgtcatc cattacacca
    14641 taaagcaaag caaataatga aataacgatt gattgtgtta gaacgacatt tctagatacg
    14701 ccgtatttgt tttctttatg gaatccgaat tttggtggaa ggaatccttc acgagctact
    14761 tggatgattg tttttgatgg tccagtaacc caagctgata attgtaaaag cacaccaata
    14821 aataccatga agctgaagat atttccgatc acttctggta agcctaggat ttgacagtca
    14881 atcaagatag gctgcgtgat atttgctaat tccatttttc catctggtac gacatttgct
    14941 acaagcatcg cattgatgac attcaataaa actaatccga tcaaagcgat aaatacgcct
    15001 tttgtataat tttttgttgc gtctttcaaa cgaggcatgt aaacagaact catttcgatc
    15061 ccaacaaaaa taaatgtgat accagctaag tatttcaatg aatcaatatg ttccaagtca
    15121 gggaaagctt ttgaccatga aaagtcacct agatagccgt ttgagactag tccgactttg
    15181 aaggctgcca aaacacctaa aacgaacatg atgactactg ggatatatac ccctagccat
    15241 acaccgatgt tcccgccgac ttttgccata tcgaatttca agttcaagat cgtgatgatc
    15301 cagtagataa ctaaaataca acctaaaacg aaccagtgat tattgccaag ttctacatta
    15361 ccaaatgtgt ttcctaacaa tggtcctaaa gtagaagcga ccattaccat acctgggaac
    15421 atttgcaccc ataatagcca tgcaacgaca aatccccatt tgctgcccag tgctgttttt
    15481 acccataact gaggaccgcc ttcttgagga agcatcgtgg aaagctcacc ggaaaccatt
    15541 gatatcggac cggcaaaaaa caaaactgca aaaattgaat aaaaaatcaa tgtccaaccg
    15601 actgcggcta acgtaggaat actccgaacc gttgcacaca gtgccattgt cagaccgata
    15661 aaggtcccaa gacccatttt acttacttca gatttactca ccgttgacac tctccttgat
    15721 tttttggata aaataacggt gtctttgaag tagtttcagc aataaacgaa acaattcagc
    15781 gaatatttga ggggattctt tgagtttatt gcttgaaggg tttcttcaaa gacaacctca
    15841 aaacaaaggg atcgaagagc ttaggtctcc ccttgctctt cagatccaaa catgcgtcag
    15901 aaacagttag tattcaagct gttttctaac atgattacct tgcttatttt gcttcgcttg
    15961 ccaataattg gtctgcgtag attttttcca atttttcttg aagagctgct ttgatttttt
    16021 cagcatattc ttcaaagtgt tcttctttgt tcatgtatgg tgtcattacg ctggcacgca
    16081 atacagttac ttttccggca cggttccatt cttcatctga gaatcctagt tggttcacaa
    16141 attgtaatgg gctgttgcca tagtctggga tagcaaagtc agtatgtgaa gttaagaact
    16201 cattaccgta aatgcttcct ttcacgtatg aagaataatc atatacgtca tggttcaatt
    16261 tattcattgc aactaagtca tcgttgcctt tttctttgaa tacatagtct accatattga
    16321 aatctggata agttaatgga tgaacttcga tttctttgtc tcctacttta aatgacaagt
    16381 cattcaagaa gttgtagaaa cgatgtgcac cttcgattga tgcacccatt aatttaccat
    16441 atcctgtgac attcaaaggt aagacatggt gtgctgccca aacgctggct gctgttgccc
    16501 ctgcttttga accttccaag atataagccc caagtaatgc tgggatatct gcgccttttt
    16561 caaatacata tgtcgcaaag taagagataa cgtttctcat gcggatatct ttgatgacga
    16621 taccaccggc agaatatgga acatagccca ttttatgtgg gtcaatcgtt acagattctg
    16681 cttcttcgat tgctttatat gcactgtgta cttcttctaa gatataatct ttgttttctg
    16741 taaagacatt gtatttgtaa tgaacatctt ttaaatcttc aaatggaatg aagttgttgt
    16801 cttcgtctaa gaaaatcgca cggccgtatc cgccataagc agcatctacg tgtaagtaga
    16861 agtaaatacc gtctttttct aatacgcgac gcaatgcaac gattttatcg ataccgtcga
    16921 ttgctccttc ttctgttgat cctacaacac cgactacacc taggattggt gttttttcag
    16981 ctgctagacc acgaacgatt ttttcaagtt cgttgatgtc catgcgatag ttgtggtcaa
    17041 ctggcactgg aatcacttgg tctaaaccga taccgatgat gtcggcagct tttagccatg
    17101 aatagtgttt agtttgtgga accaaccatt ttcctaattt ttctaaatgt tttccgctac
    17161 gtgctgagtg agctttgatt tcgtcgattt tttctgggac gctgtctaac agattcatga
    17221 tttcttctgt tgacaagttc attaattccc aatcgctttt tccagcaact agttcaggtg
    17281 tcacttcttt cattgcaagc ggcaatgatt tgatgttgcg ggcataccaa agtccttcta
    17341 agtttgctaa agaaccatca gcaacgatgt ggccccagcc atctttatag ctcattaatt
    17401 ttgcaaattc cattcctact tcttcttcca tttggcttgt tgcaggagaa gattcatagg
    17461 caacgttatt accattccat agcatagcaa aattgtacgc tagtaaagat ggcatcaatg
    17521 tttcagagtt catatgaccc cagtaacgtc cggcattatg ccaaggaacg gaatgggtac
    17581 gcatccgcgc tgaaatttct gatagaacat cctttgtttt attcacagtg tgttcaaaac
    17641 tagcactgct tttttcttct ggcgtaataa taggcatgtc ttgaggcatg tagttttgac
    17701 gccagcctaa atgttcatcc accaattcat tcaacaaagc tttatagatt tggccgttct
    17761 cagctttgtc cccaatgaat agggcattta ggtttagatc tttcgacaat gattcactca
    17821 tagtgaaacc ctcctaaaaa aatatttaaa ttttgtcgag ccctacatta cacctgttct
    17881 tctattctgt aaactaagtt ttggcctgat ttttaatcat attttaatat gtatcaatta
    17941 tccgaattgt tcacactttt gaaataatta aaaaaaacga gggaatttac aaatgtaaac
    18001 tccctcgcaa agattgtatt aacgacaacc agcgttctat tttaggatgg gtttcaaaat
    18061 tggaatgttg taatagtatt tccctttttc aaggtaaaaa cttactaaat tctaatcaat
    18121 tactttggcc aaaaagtaat ttttcttacc ttttcgaata accacaaact taccatcgaa
    18181 ttcatcggat ggatttatga caaaatttaa atcggtaacg cggtcaccgt taatacttat
    18241 agctccgttt gaaacatctt cacgtgcttg acgtttagat ggttcaattt ttgtggaaac
    18301 aagcagttcc acgatatttt caggtgtgct tgaaatttca acgttcggca ttttaccgaa
    18361 tccttgcgcg atttcttccg catttagttc tttaatattt ccagagaaca atgcttgcgt
    18421 tattttttgc gcttctttca agtcttcttc actatgcaca aatcttgtaa cttcttctgc
    18481 caaacggcgt tgtgcttcac gtttctcagg ttctgtctct acttttttcg ctaagtcttc
    18541 gatttcttct tgagacaaga aagtaaagaa tttcaagtat ttcactacat cgcgatcatc
    18601 ttgattcaac cagaattggt agaactcaaa tggtgaagtt ttcttcggat caagccaaac
    18661 ggcaccgcct gcagtttttc cgaatttcgt tccgtcagcc ttcagcatca atgggatcgt
    18721 taaaccgaac gcttctgctt ctggtccttc taattttcgg attaggtcta atccagctgt
    18781 gatatttccc cattggtctg ctccaccgat ttgcaattgc acatcgtatg ttttatgcag
    18841 atgcaaaaag tcgatagatt gcaggatttg gtaagtaaac tctgtaaatg agattcctac
    18901 ttccaaacgg ctggcaacga tatcttttgc taacatcgtg ttgatgttga agtttttacc
    18961 gtagtctctc aaaaattcaa gtaaagagat ttttgacaac cagtcgtagt tgttcacaaa
    19021 tgtgatattt gcatctttac caaacaattt tctcatttga ttggaaagtg cgtccacgtt
    19081 atgttgcact tgttccatcg tttgcaacac acgttctgtt ttgcggccgc ttgggtcgcc
    19141 gatcgttcct gttccgccgc caatcagaat atatggatga tggcctgcca attggaatct
    19201 tttcatcatc ataaatggaa tcaaatgtcc gatatgcatc gaatcaccag ttggatcaac
    19261 gccgcaataa agtgaaatgc tcttttcttc aacgagctcg cgaagtcttt cttcgtttgt
    19321 ttgctgatta atggcgtcgc gccaagttaa ttcatcaata atattcattt tactgacctc
    19381 cgtgtagttt ttttatgaaa gcaggaacct gctagcatat gtaattaatt atttcttcag
    19441 gataggatag gaaataaaaa aagtcccttg gcatataagc caagggacga aatctcgcgg
    19501 taccacccaa tttgtatgtc tagatatcca acatacctct cgaacattta acgctgtcgc
    19561 gtggcaatca ctgccaaaga ctcctgaaat gtaattcgct ttaaagcatg tactggtttg
    19621 cagcgaccac cagctttctg aaacattggc tttaacaact acttcgtttc gatcttcgtc
    19681 ttgttattat taatatgtgt ctatcataga gcgcaacttt ttctttgtca acagaaaaag
    19741 gatatttttt ttaaattcct cattttttct tttttgaatc cgctctaatt ccgaacattt
    19801 tattttcaat tattgttaaa agaaataact ttttctgtat tttttctgca atttatcgag
    19861 aagtcacttt actttgcctc ttattctttc ttcgttacaa taaggaatgg gacaagtaaa
    19921 aaaatgaaaa agcaagggac gaggtatatg gaaaaaaagc aaaaaattat tttaggagcc
    19981 acttctgctt taactatcgt tattttaatt ctaagtttgt tttttgtcat ccgatcatct
    20041 acaaaaaaag aaccaatcat tcctgaaaaa aaaataacag aaaaagcaaa agaaccgaca
    20101 gatgataagc aacaactagt tactcaagca aaaaatctgg ctcaaagcta cgattatgac
    20161 caagcgattg cgttattgga aaaagatagt aagaacggat ctactgaaac acaacagctt
    20221 cttcaaacac taaaaaagga gaaagaacaa ctgatcgact ggtctgatcc tactcagatc
    20281 tctcatgtct ttttccacag cttgatcgtg gacccgcaaa aagccttcca ctctcaacag
    20341 gcacaaggat acaaagatta tatggtgact gttgaagaat tcaaccgttc gatcgaacaa
    20401 ctttatcaaa atgattttgt tttagttaat ttgaatgatt tgatccaaaa agacgaacaa
    20461 ggaaatcttt cctttaacgg gcttgcgcta cctgaaggaa aaaaaccatt ggttctttca
    20521 caagatgatg tcagctatta tgaatatatg gataattccg gttttcctag ccgattggtc
    20581 gtatcaaata acaatgaaat caaaaatgtc tataaagaga aagataaaga agaaatcggt
    20641 gactttgaca tggttcctct gatcgatgcc tttgtcaaga aacatcctga tttttcttat
    20701 cgaggcgcaa aaggtacctt ggccctgaca ggttacaacg gagttttagg ttatcgaaca
    20761 tcaaaatctc aatatggaga caatgaaaaa acaaaaaaag agattaaaga agctaaaaaa
    20821 gtggcggaac agttgaagaa agacggctgg agctttgctt cccatacatg gggtcacttg
    20881 aatatgactc aagcttcact agaagatgta aaaaaagaca atgaattgtg gcagcaagaa
    20941 gttgcaccta tcctaggaaa aacaaatatt ctgatttatc catttggtgc agacatcagc
    21001 gactggcagc cttattcagc agaaaatcaa aaatttgctt acttgaagag tcaaggtttc
    21061 gatattttct gtaatgtcga tgcttctaca ccagcttggg gacaattagg tacggatttc
    21121 tatcgaaatg ctcggatcaa tatcgatggc attcgttttc aatctgattt agacggaaaa
    21181 aatcctattc ttgatccatt catcaatgtc catgatgtct atgacaaaga agcacgcgaa
    21241 tctgcttgat tttacgtcat ttatgaacca aaaaagccga actgacattt tatcgtcagt
    21301 ttcggctttt ttatgcttta tttcttcttc ggtgcgattc ccttgatcag gacttctgtc
    21361 cattctgctg tatatggaag cagttttgcg tatatctccg gcttagaaat tccttctacc
    21421 attgcttgaa aatagaggat caagaactca tccgaatatt tcaaatccac ttttccttct
    21481 ttccgccctc gatggaaaag atcaagcatg atactgaaac tttcttgcgt atacgcatcc
    21541 atcgcgtcag aaaattcttt tttttctttt tttgtatagt atgtcatcaa atcgatataa
    21601 aattgtttgt tcactcgatt gagataacgg attttgtttt cactcatggc aatcagtgtt
    21661 tcttcaaatg gaagattttc cgcaatcaac gctttcgctt cttgccctaa atcattcata
    21721 aatgcaaaaa atacttcata aatcagccct tccttgctgc caaaatattt aaaaatcgtc
    21781 gctttactta cctgagcgtt ctcagctacc ttatccattg tcactccagc ggttcctatg
    21841 tctgtgttca tcaagtcaaa agctgcttgt aaaatctctt tctttttctc ttgtgctctc
    21901 ttttcaaaac cgttcatttg tagagcctcc cgtaatt
//
LOCUS       DAZKNV010000047        21773 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000047 DAZKNV010000000
VERSION     DAZKNV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.047"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(155..1963)
                     /gene="uidA"
                     /locus_tag="ACG8M1_001966"
     CDS             complement(155..1963)
                     /gene="uidA"
                     /locus_tag="ACG8M1_001966"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFQ0422648.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(1986..3752)
                     /locus_tag="ACG8M1_001967"
     CDS             complement(1986..3752)
                     /locus_tag="ACG8M1_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFQ0422649.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(3765..4559)
                     /locus_tag="ACG8M1_001968"
     CDS             complement(3765..4559)
                     /locus_tag="ACG8M1_001968"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0422650.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(4569..5945)
                     /locus_tag="ACG8M1_001969"
     CDS             complement(4569..5945)
                     /locus_tag="ACG8M1_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0422651.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILGLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(6065..6712)
                     /locus_tag="ACG8M1_001970"
     CDS             complement(6065..6712)
                     /locus_tag="ACG8M1_001970"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFQ0422652.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(6796..8223)
                     /gene="uxaC"
                     /locus_tag="ACG8M1_001971"
     CDS             complement(6796..8223)
                     /gene="uxaC"
                     /locus_tag="ACG8M1_001971"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFQ0422653.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(8297..9376)
                     /gene="uxuA"
                     /locus_tag="ACG8M1_001972"
     CDS             complement(8297..9376)
                     /gene="uxuA"
                     /locus_tag="ACG8M1_001972"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0422654.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(9379..11010)
                     /locus_tag="ACG8M1_001973"
     CDS             complement(9379..11010)
                     /locus_tag="ACG8M1_001973"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFQ0422655.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            11314..11985
                     /locus_tag="ACG8M1_001974"
     CDS             11314..11985
                     /locus_tag="ACG8M1_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0422656.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(12145..12336)
                     /locus_tag="ACG8M1_001975"
                     /pseudo
     CDS             complement(12145..12336)
                     /locus_tag="ACG8M1_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(12704..13045)
                     /locus_tag="ACG8M1_001976"
     CDS             complement(12704..13045)
                     /locus_tag="ACG8M1_001976"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422657.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
     gene            complement(13142..13594)
                     /locus_tag="ACG8M1_001977"
     CDS             complement(13142..13594)
                     /locus_tag="ACG8M1_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422658.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(13601..14149)
                     /locus_tag="ACG8M1_001978"
     CDS             complement(13601..14149)
                     /locus_tag="ACG8M1_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFQ0422659.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(14194..14526)
                     /locus_tag="ACG8M1_001979"
     CDS             complement(14194..14526)
                     /locus_tag="ACG8M1_001979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422660.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(14540..14797)
                     /locus_tag="ACG8M1_001980"
     CDS             complement(14540..14797)
                     /locus_tag="ACG8M1_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422661.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(14992..15534)
                     /locus_tag="ACG8M1_001981"
     CDS             complement(14992..15534)
                     /locus_tag="ACG8M1_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFQ0422662.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(15555..16646)
                     /locus_tag="ACG8M1_001982"
     CDS             complement(15555..16646)
                     /locus_tag="ACG8M1_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0422663.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(16654..18864)
                     /locus_tag="ACG8M1_001983"
     CDS             complement(16654..18864)
                     /locus_tag="ACG8M1_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFQ0422664.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(18880..21408)
                     /locus_tag="ACG8M1_001984"
     CDS             complement(18880..21408)
                     /locus_tag="ACG8M1_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0422665.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(21460..>21773)
                     /locus_tag="ACG8M1_001985"
     CDS             complement(21460..>21773)
                     /locus_tag="ACG8M1_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFQ0422666.1"
                     /translation="VNAATFLLVVIFEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCV
                     LALAKLKPDGKKVHFYLWDWFCYMIRMMNGDCVYYNWDKVSNNALEELLFVNKYVYLE
                     D"
BASE COUNT         6943 a         4453 c         2903 g         7474 t
ORIGIN      
        1 atacaacaat cagaaagccc ctttttttcg aaaaaactag aaaaaaaaca taaaaatatt
       61 tatcattctt taaacagaaa atctttctat aaaaaacaaa aaaaaacgat taggctaggc
      121 taatcgtttt ttgaacattc ttaaaaaatc caaattattt tttataactg aaattgggta
      181 ttgatgacca tcgtttctgt agatagtaag caatcatttt aggttttcta tctctagtaa
      241 agattccttt cttatttcct tgcactctta aaatcccttg acttgttgca aaatctgcaa
      301 aattccacac ttgttcacca acaaaatttt cacatgtatc tattacttcg tgatttgctt
      361 cgtaataagc cacttgatac tcttctgtaa acattgttgg tactgtatca tgaaatccag
      421 ctactgtatc tgctccatat tctgtaaaca ttattggcgt atcaggacat ctttccatcc
      481 atccatctag ctcttttttc aacagatatt ttgcatgtgc cagatcccct cccgaaacat
      541 accaaccata ataacgattt aaacataaaa catcgacaat atctcctacc ttacaaacat
      601 ctggcgttga ttttagataa gtaacgattg ttacaggtct tttctgcgga tcaagttctt
      661 tagttaattc aactaaaggt tcaaaatatt ctttagcacc ttcggaatcc gaatctggtt
      721 catttgcaat agaccacatt acaacacttg ggtggttctt gtcgcgttct atcaattcct
      781 tgatcaccgt tttatgagaa ttttctgttc gtatctcttt ccacgtatta tgtttttcca
      841 cattatcatc taataaagtg gccatgaaat ttaaatgtaa ccctactgca ggtacttcat
      901 caataactac aataccttct cgatctgcta atcgcataat ttcttctgag taaggataat
      961 gtgatgttct aaaagaatta gcacctatcc atttcattaa attaaaatct ttaatattta
     1021 cagcctcatt caaaccacgt ccattaacat acgaatcctc atgcttacca aatcctttaa
     1081 aataaaaagg tttattatta atcaaaaatt tgccattggt aacctgaaca ctgcgaatac
     1141 caaattcttc tgtataggta tcgatcactt tattatcatc aattaaacta attttcatac
     1201 tatataaata agcgtctaga ggttcccaaa aaattggatt cttaagctga atcattcctt
     1261 tctttccttc agcttcagct acaagttgag cctcttcgtc atatatcgct attaagattt
     1321 ttccggtcca ttctgtatcg atattgaatt ctacacttgc atccaaatca gttattcttg
     1381 tattaatagt aatatcactt atatagtctt tcggagttgt atataactta acaggtctat
     1441 gaatacctgc ataattgaag aaatcaaaat taactaagtt ttcctttttt atatccccat
     1501 tttcctgtac tgtttccttc ataatcccca caggtaaagt actatcgtca ataatattgt
     1561 ttacagcaac tgtaattcga ttattcccgt cttttacaaa ccgattaatt tcagactcaa
     1621 atggtgtaaa cccacctttg tgttgagtaa taaactttcc attcaaaaaa acttttgctt
     1681 catgtgttgc agatccaaaa cgaagaacta atctttcttc taataatctt ttaggaagag
     1741 tcacttcttt ttcataccac acccatccaa catgatttct aatgttctct gtttcaaata
     1801 aatcattata agaagaggga actgaaatcg gataactctc tttttcattt attggttcta
     1861 aagcaagttc ttcctgtaag tcatcatttg tatctaattt aaatctccag agaccgctta
     1921 agtcaattac ttgcctcgtc tctgtcataa tgggatacaa catataaacc actcctatct
     1981 aaatattaaa taaatgtatc ctttaaacca caataagcat ctattggact tactccctta
     2041 aattcagaaa gacccattag tttgtccacc aatatttcta aagtttcttg ttttccatca
     2101 taagtattaa tataagtctt tacttgaggt acatcagcca aatgaaacgg acactgtaca
     2161 gatacaaaaa ttgttggaat ttcatgaatg taaaacggta tatccggagt tcctttactt
     2221 gctggccaga caattcgttg aactgtgcct ggattaacat tagctatatt aatgatcaag
     2281 tcatattttt tagttaaatt tttaattggt ctcttagcag catatattcc agctatattt
     2341 ttaatttttt cttcttgcga taatcctttc aattcttctt caggtgaaat gtatttttca
     2401 acttcaaatc cttttgctga caaaatctgt ttcaataaat caatggcttg aggtctattt
     2461 ccagcaacta cttcaccaaa cccacctttt accccatgta catctactag taaaatcctt
     2521 ttatattttt ctggtacaat aggccaaata tcttgtttat ctttaactaa tgtaattgct
     2581 tggtcagcca cctctttaaa aattgattta ttttcaatta aaccaatttt ttccagagct
     2641 tcttgcttag gtaataaaat ttgttctttt gcttttttgt gtaatcccaa tttagctttt
     2701 aaccctaaaa ttctttttaa ggcatctaat aaccgatcat cagtgataat tcctttacga
     2761 tagccttcca tcatataatt aaagtcttca tctggatcat taaaaaatag aaatagatca
     2821 catccagctg caatagaagt gggcaataat tctgatcgtt tcattgcccc agtcattcct
     2881 aacatatgac tagcatcagt aactactaat ccattaaatc cgagttttcc tctaagtaag
     2941 tcagtgatta attcttttga taaagttgca ggaagtaaat cttcatcttt cagatcagga
     3001 ttaaaatgtt ttgaataagc tggcatatgg atatgacctg ccataattga aggtaatcca
     3061 gcttctatta agcctgagta tacttttcca aaagaattat cccattcttc cgtacctaaa
     3121 ctattaatac taaaagatag atgctgatct cgttcgtcaa taccgtcacc agggaaatgt
     3181 ttagctgcag gcaaaattcc actctcctga atacctttca tataagctaa actaagttct
     3241 aaaactttat cagggttttg tccaaaagat cgactagaaa tgataggatt tctccaattt
     3301 ctattaatat ctacaatagg agcaaaactc cagttacatc caatagccga tgcttcaatc
     3361 ccagaaactc tccctaattc ataagcatat ttcgcatcat ttgttgcacc aatttttact
     3421 tctacaccaa cttcagtacc atctgtacaa gctccgttac cacctgcttc cgtattagca
     3481 gcaattaata gaggaatttt actttctgtt tgtaagatat agttttgatc atatacctca
     3541 tcagcagttc ctggattata tcgtacagct ccaatatggt actgattgac catattactc
     3601 aagtaatttt tatcacgact agatcccata ttaacaaaca attgacctat tttttcttcc
     3661 aaagtcatag aatcaatcgt ctcttcaatc caagaaatag catcttcatc taaattatat
     3721 ggtttttttc gtaaatctac ttttatagtc attttctttc tcctctactt attagtaaga
     3781 tttttccaaa aagtatctat atatttttgt tcaatatcta cataatctcc cgataaacat
     3841 ttaaataaaa catcagttct taagttttcc catgattctt tttctttatt gaccaaaata
     3901 ggataaaaga aaactttatt tttatttgca gcttctagat caccaggaga atcaccaatc
     3961 attaatatct tatccaaatc acaaccattt tcaattacac ttcgaataat atcttctttt
     4021 tttcctttat cttgacaaca cagttcatca actaatgata ataattcatg tctttcccat
     4081 tcttcttgaa cagcttcctt attagctgag cttacaataa ttatcttccc atattttttc
     4141 agagctttta tagtatctct agcacttaaa aagggtttat ctaatccttt tgcttgacta
     4201 atctgttgat tgacttcttc cgaccatttt aaagctttta ataaatcctc tgactgagaa
     4261 tattctattt ccctcttcaa agatggatta gacaattctt ttgttagaga tacccagtgc
     4321 tttaatcgat taatcgatgt tacatcattt ttttctaatg ttttaactaa acctaaaaat
     4381 ctgtttattc cacgagtctc tgaatataaa ttaatattat tccaatcctg taggaatttt
     4441 tctctatgat gaacatcaaa aatctctgca gcaattggtc cgaaaaagag attgtgttta
     4501 taagtcatcg tatccataac acagccatct gaatcaatac aaaatatcca attattcata
     4561 tttctctcct atttatgttt ttgttttaaa agctcgcaat tttctaagac tttatcttta
     4621 gataatggat aaaggaaaaa taaaattaat cctacaatca gaaaacaaat tgatggaatt
     4681 aatgttgaag cgttatataa cttttctaaa acatctcccg tttgtacatt tgctaaagag
     4741 tcatagccta taatagaaag agtccaacct ccgacgcctc cagctagagc ttgacctatt
     4801 tttctagcaa aagaatatac cgcatatacg gtcccatctt ctctttgatc agactttact
     4861 tcttgatcat caataacatc agtaatattt gcccaaataa cagtattaaa cacacccaaa
     4921 cccatatagc caaccgaact aagaattaag aatacataca tattactagc ttttatcaaa
     4981 aataagatca aatatactat tgctgaaaag aacattccta ctgatgccag ttcttttttt
     5041 ccatattttt tacttaaaaa caaagttaaa ggcgaaacaa ctattaaacc caaaatagga
     5101 ttgataaaat tcattaaaac tattccctgt gcatcattat agtaatcagg aaatacataa
     5161 ttattcatac tcataattaa taattgagca aggagtaaga aaatagccgc accaattata
     5221 gaaagtaatg ccctattttt aactaaccct tttaaagatt ttaacaatga aactttgtat
     5281 tgagattggt caattcttac tcgttcagta gttagtttat aacatattaa ataacaaata
     5341 agtgcacata tcgaaaatat tcccgcaaca attgtaaaag ttgatccacc acgaactatt
     5401 tgagcgcctg aatcatctct tgtataaata aataatggtg ttaatacacc aatgaccaaa
     5461 cttgctaaag tagctccaac atttcggaat gtcgatagca ttgttctttc ttctgtaata
     5521 gaagtaatag ctgatgccat tgatccataa ggaatattta tagatgtgta aaaaatactc
     5581 ccccataata tatacgtaac atacatgtat actaccttaa cgctcataga agctgaaatc
     5641 atagaagttt gatacattaa aaaacttgct aaagcgactg gaccactcat tcttaaaatc
     5701 cacggtttaa acttaccctg cttagttgct ttcgatctat caacaatacg ccccatagtt
     5761 acatcagtaa ctgcatcgat aaatcttgct actaaaaata atgttccaac ggcagctccg
     5821 cttatcccca atacttttgt ataaaagatc attaaaaaag aactagcaaa aatgaaagta
     5881 aaatcgtttc caaaatctcc aaacatatat cctattttgt ctcttatacc aaattttctt
     5941 tccatacaat tctctccctt ctgttgttaa gcgttttcat tctgatgaaa gtacgtacta
     6001 tactctgaag cgtaaagagt cagtatttat tttttacatt tcagagtatt atttgttttt
     6061 tctcctaata attctttatc tcataaaact tatctatata tttactagct actcgactta
     6121 cttcttcaaa atcacctttt tcaacagaag ccaataaatt cccacctaca ccaactgcaa
     6181 caactcctac ttcaaaccaa tcttctaagt tctctatact tactccgcca gtaggcatta
     6241 tatttacgtg tggtaatgga gcttgatagg cttttacaat ggatggacca aaagcagaac
     6301 ctgggaatag tttaatgata tctacgccag cagtaagtgc ctcctttatc tcagtaattg
     6361 tcatacaacc tggtaaataa ggaatttgat ataaattaca aatctcagct gtttgtcgat
     6421 caaaagatgg actaacgata tattctgccc cagccataat tgcgatacga gcagtaaacg
     6481 catctaaaac cgtaccggct ccgattatta catctttttg atcagcatat tttttagcaa
     6541 tttctttgat tatttcttca gcattaggaa ctgtaaaagt tagttcaatc cctttaattc
     6601 cacccgcaat aattgaattt attgctttaa tggcctcatc cttatttttc ccacgtacaa
     6661 ccgcaatgac tccagccgct tctaacttac ttaaaatttc tacttttttc atatctatct
     6721 ccttccttta tggatacata ctttgtctag ctgtactaac ttacaaagaa taaatttaag
     6781 cttttatttc aagtattatt ttctacttcc gatttcaaaa aaattaaaat aattatacgc
     6841 attacgataa caaatattct ccactatctg actaagatac atttcatcat ctggaattcg
     6901 gcctgcttta acccactcgc ttagtaattg acataatact cgacgaaaat actcatggcg
     6961 aggatagctt agaaaacttc gagaatcagt caacatacct gtaaaattcg acaacaaact
     7021 ttgttgtgcc atcgtagtca actgttgacg cattccttca gctgtatcat tgaaccacca
     7081 agcacatccc aattggattt tttgaatcat acccccttgg aagctttgca ttgctgttgc
     7141 tagtggaagc caatcagttg gatttaatga atataaaatt gtttttggta agcacccact
     7201 cttttcagcg gtatcgaaca atgctacaac attttgtgtc aaactagctt gatcccccat
     7261 cgaatcacca ccgacatcta ctccaatttg ttcctttaat atacttgaat tatttcttaa
     7321 agcatttaaa tgcatttgca tcgtccaacc atatcttgta tactcagaca tcaaatgtaa
     7381 ttgaatacct gtaacaaatt gtgcaatttc tgataaatgg aaatccgttt ttcctgctaa
     7441 agcttttatt aacagattgt cgagtatttt ttcatctgct atttcataaa aataagtatt
     7501 caaaccgtga tctgctaatc gacagccaat ttgatgaaaa tgatccactc gttggctcaa
     7561 tgcttgcttc aacccattaa agtctttgat tggtatagcc gctgtttgac taagttttaa
     7621 aatatagttc gaaaagcctg atgatttgat actccagacc ttatctggac ggaaagtagg
     7681 taataccttg aaagaattat cctgtttaga aagctcagta tgataccaca agtcatctgt
     7741 aggatcatcc gttgtacaga tggctttcac atccatcatc tccaacaatt ctttcgggcg
     7801 ataggaatcc gtttgaattt tttcgttagc acgtcgccaa atttctggtg cattcttctc
     7861 agaaattgtc aaatcaatat caaagtaacg ttgtaattcc aaatgagacc attcaaaaat
     7921 aggattacct ggcgccttct ccactgtttt tacaaaagct aaaaattttt cataatcatc
     7981 acctggacca ctgatcaact cttcttctat accattagct cgcatcaatc gccatttata
     8041 atgatctcca gctcctttat catttaacca tacctgagtc aaattcttgt attgcttatt
     8101 ttctagcaaa tatgctgggt ctaaatgaca atgatagtcg ataattggtt ggtgttttgc
     8161 aaatttatga aaaagtcttt tagctatttc attctctaat aaaaagttct tatctaaaaa
     8221 catatttaaa cactcctttc cttccgttag tttttagaag agaaaatttt tcctctaaat
     8281 aaactccctt atataattat ttactcgccc ccttttcaag cgcttcccaa ataccattta
     8341 aataaactgc acctagagct cggtcatata atccataacc aggtctaccg gtttctcccc
     8401 aaatcatccg accatgatct ggacgaatat agccattaaa tccattatcg tacattgttt
     8461 ttaatatctt atacatatct agagaaccat attctgattt atgcggcgct tcgtaaaaat
     8521 cgagtccatt gtcacttaaa tatttgatat tacgaacatg tgcaaaagga atccgatccc
     8581 gttgacaaaa ttcagataga atttcataga catcattatc tggtcgttct gcaatacttc
     8641 cagtacataa tgtaatacca ttagaaggag aatccactac attacacaac caatctaaat
     8701 cgtcacgatt tttaacaata cgaggtaatc cgaaaatgga atatggtgga tcatctgggt
     8761 gaactgccat tttaatccca acttcttcac atgtcgggat aattgctttg agaaaatatg
     8821 caaagttctc tcgtaatttc tcttcatcaa cttctttata ggcttctaat aattgcttaa
     8881 tttgtgataa ccgatgaggt tcccaacccg gcaattcaaa attattagta gaattttcta
     8941 cttctctaat aatttcctcc ggatcagtag ggatattttt tgaaatatag gctaacgtag
     9001 aagacccatc atctaaacga taatccaaat ccgattttac ccaatcaaat actggcataa
     9061 aattataaca gataacctca atcccaaatt ctgccaaatt gcgaatcgtc tgtttataat
     9121 tctcaatgta ttgatctcgt gttggtaaac caattttgat atcatcatga acattaacac
     9181 tctcaataac tttcaaggta agtccattgg cttcgacttc atcttttaaa gatttaattc
     9241 gttctctcgg ccaaacctct ccggctggta tatccattaa tgttccaaca attcctttca
     9301 ttgctgggat ctgacgaatt tcttgtagtg agattttttc ttcatttgcc ccataccatc
     9361 taaaagtcat ttccatagtt actttcctcc aacttctgtt atatatttat tgattgtttt
     9421 acgaactgct tgaggaccta ctagcatttc gcaaaagatt ttttcagttt tctttcctac
     9481 cccaacttga tataaatcta aaccaaagat ttctttattt tctaaaattt cctgtaccgc
     9541 acaatgaatc tttgaaggat cttgttcacc taatttcaat actgataatt tatcctgcaa
     9601 ctctaccaat aacggatcag gacttggcac aaaattttcc ccttgatcat cgactgccag
     9661 taaataacgt aaccaagcag caatagcgat aggaataaat gttagatttt ctgcatttcc
     9721 gtctttttcg acatactttt taattgtttc accatagcga atcgctactt tttgagaagt
     9781 atctgttgca attcgttgtg gtgtatctgg aatataggga ttaggcaaac gtttattaat
     9841 tacttcatca ataaattgtt ttggatcaat aatgcctgga ttttcaacta ctggtaaacc
     9901 ttctaaataa cctattcctt tgattaaacc aaccaaatca tcatcctgca tctctgctga
     9961 aattgattga tatcctagca gacaacctgt tactgccaaa gcagtatgaa gtggattcaa
    10021 gcttgtcgta accttcatga tgtctgcttt atcaaccgtc tctctatctg tcataatcac
    10081 accagccttt tccaatttag gccggccatt tggaaaacta tcttcaataa ctaaataatg
    10141 aactacctca gtattagtga aagcagcaat attggtatgt ttttttgtgt gaatgatatc
    10201 taaatcctcg agccccatca tcaatagatc ttcctttaca ttctctgaag gatttggcgt
    10261 aattcgatca atcatactcc aaggaaaagt cactttttct ttatccttta aataagcaat
    10321 aaatttttca gaaacatatc cttctttttg ccaagcttct gcaatcgtaa aaatactatc
    10381 ttgaaaacgt tgaccattct gtgagaaatt atcagtagaa accatcgcaa tcggcaactc
    10441 tccagcatta aatctgctat ataacaagga tgttacaata ctcatcgtat gttgaggatt
    10501 gctaggtcca gatttgatat cagctttgac taccgaaaag aattgccctt tagaatcttt
    10561 taaactgtaa cctttttcag taatagtaaa cgttgtaaac tgtaatttag gatcttcaaa
    10621 atatttaacc actctttgat agtccgctat attcttcgga ttgcaatata aactatcagc
    10681 cgttactgcc aaaagtcttt ttttgagttc accatctcca ctcataacaa tttccaaaat
    10741 gtcattgtta tagtcatgat aagctttttc cactacttct tcatcaaatg tttcacacac
    10801 aactactcct gtttctaatt cattttgatc tgctaagcat tgagcaattt ctgcatgaaa
    10861 tcctcgataa agatttcctc caccaaaatg aagccatact ggatgttgct ggccttcttg
    10921 cttaacttct ttgacatcaa aacacggcag tagaatctgc atttcattga attcttcgat
    10981 agaattttgc caatttttaa tcgaaaccat aattaacctc ctcaaactga tatgttagtt
    11041 ttgatacatt ttatatttta aaacccattg taaccgttgt caatataaaa agggaataaa
    11101 cttgcttttt tctaccatat cagaatgatt gtatttttta ttcagaaaaa taaaatactc
    11161 cttctttttg gactgatttt atcgaaactt attttttctt tttttcatgt attcttttat
    11221 ttttataact agtgtattac ttcaaaattt gatattatat ggcatgaaca gaattaaaat
    11281 atcagttaaa ataaaagtta aggagcattg tgtatgacaa ttaaaactag tctccaaaat
    11341 caagcttacc aatctattcg ccgacaaatt atctatgctg acttagaacc tggaaaaaaa
    11401 gtatcagaaa aaaaattaga agaaacactt tctattggtc gtacaccaat acgtgaagca
    11461 ctgattcaac tccgacaaca aggtcttgtt gatacaattc ctcaaagcgg aaattatatc
    11521 tcattaattg atttagattc ggccaaaaat gctcgatttg tcagagaaca tttggaacga
    11581 caaattatgt tagagtgttg tgccaaaatg aataaccaaa aaaaacggat tttagaaact
    11641 ataatttcag aacaagaaaa agctgttagt caaaaaaatg ctcgtagttt ttttcataat
    11701 gataatttat tccataaagc ttgttttgaa attgcagagc gagaagaagt atggcaatgg
    11761 ttagaaaata acaatacaca cttagaacga tttcgatggc tacgagtaaa aacggaagga
    11821 ttaaagtggg aaaaaattat ggaacaacat tatcaactat ttgaggcatt aacaaaacaa
    11881 gatccagaag aagctaactt tctaacatcg ttgcatcttc atttaatgct taatgagcaa
    11941 aatattgttt tagctactca tccaaaatat ttcaaaaata tataactttt aactcttttt
    12001 aaattaaatg gttgttctga tcagaaaaat atcgcttgtt ttcttattat gtaatatatt
    12061 tcataaacta ttctgcataa caactattgt ttgtactttt tacattggat aactaattat
    12121 gactgctgat aacttttgat attaaactag tatctccaat acaaataaaa aatagatatc
    12181 ttgttcatca aaattagttc gtggatactt accttcattt acatcattca gcggtttccc
    12241 attttctttt attctattat ttcattttct aatagacttg gcttcatttc gcaatacttt
    12301 ttttcaatag gcatcaaatt ggtgttgttt agatatttag ttgtagtttt gtgacatgat
    12361 aagtatgctc ctttttctct tttccactaa tacaacgatc aaagggtgct tttttcaaaa
    12421 aactagaaaa atcaaaataa gattcgtatt ttgattctat atatcctgtt tcaactacat
    12481 cttatatttc acaatagaat aaatagcctt ttgcatagct gcttaactta taagaaattg
    12541 caatttactt cttcaaagtg aaaacgaata tgagtaaaat aaaattattc ttcttacaga
    12601 taattaaaaa tagcgcgtaa caaaaatcgg cattcaatca cataattagg attgatgccg
    12661 attacttata ttctacgtat agttttagta ttcttatttt ttatcaccag taaccaattg
    12721 agaacagccc taaagcagaa tagtctttta tctcaaaacg cttaatttca ggcttaggaa
    12781 tatgaataat cttttgagta tattctttct cttttaatct tactgaagaa ataccactgc
    12841 ctatcttttt tacaaatatt tcatttggtg tacagactaa taaaacaata tttgtaatca
    12901 atccttgcac taaagaatta aaaggaagac tatttaaaac agggtgtgca taactataac
    12961 atgtgaagta gttattttga actttaactt ttaaaaactt taaaaataat cttatttgtt
    13021 cttctaaaca atcatctata ctcatataat cactccacta attaatctcc ccaaaaagac
    13081 acagcattaa gagatatacc aacacaacag tgcaaataac tctacatctt ccttcgcaac
    13141 cttatttcaa taaaccataa aaattatttt ttaatagaaa ctgaaaatta aaactagaaa
    13201 aagtagtttt accgaatgta agagcatcat caccatcaat atagaaatac attcttttcc
    13261 agttacattt aatttttaaa caaaattctc cccaaaaagg aactttttct agtgaaaact
    13321 tggtaatctc tttgtaatta attcttgtta aagaataatt aaacacttca tttttacttg
    13381 ttattttttc attgactata actagttcat ctggtaaaaa aattaaccaa caaacatcga
    13441 caaacagtaa atgatataat ccatttccac ctccaagcat attcaatact ggtgaacatg
    13501 ccttagaaac acgaatatag ttatggttta aatagatatt ttctttaaac attgcttgtt
    13561 taaaagccat atgctcttgt tctaaacttt tcataaactt ttactctaat gcacagctag
    13621 cagcagctgc tgcaattcct gctacaatat ttaccttagc taactcttta gctgcagctt
    13681 ttcctaattg tttttctgca atttttaata ataaatccgc agctttttca aaattaaaag
    13741 cttttaatgc ttcaataaaa tctccctgcg tacctatagc ccaagccact cctcctccag
    13801 gaagagaatt aatggctaca catccagcat atcgtttcca atcaactttc tccattctag
    13861 gaacaataat atgttcataa aagactcttg ctgctcttcc ttgttcgtta tcttgactga
    13921 ttcgttcacg aatagcacca aaatccttta tatggtatac accatgttcg tctaaaaaac
    13981 caactgtatc aaaataaaaa gttaattcat ctactaattt attctttatt tctaaatcaa
    14041 ctgtattcac tttttctgtg gcatacacac ttgttccagt actaacaaaa gtacttaaac
    14101 ctaataagaa aacacctaaa acaccaaata ttttaattat tcttttcata atttctcctc
    14161 cataaaaaat aagttacttt ttaaatatct tgtttatgaa ttcattcccc aaaggccttt
    14221 taagattgat acagcagtcc gttcacttct tttagacttg tcatacaagt cttttaaatg
    14281 atcccatatc agactagttt gtctatctag cttcaatcca ttaaacgcta atgaacggtt
    14341 cattttttct attactttag ataaagctac agaaattttt ataccttcac aacgcgcatc
    14401 ttggatttca ataatagtat catcaattag tttttgaatt tcttgcctat caacatattc
    14461 aatcttagaa agagaatctt ttaaagctac taatgattca acgatttctt ttttctcttc
    14521 agacattttc ttcctccttc tagtgacccg taaagccatg tagagcagag tccattgaac
    14581 cagtaattac actatctaca acgccattcc aatttactct acattttcca tttttcagat
    14641 ttgtcggtcc atacggatag cctttttgac attcaatgtt cggattatac cagataggat
    14701 tataccattc agccgcagaa gcagattcag tcgatacaaa caatcccaca ccaacaaatc
    14761 caatacacat cacactatag ccaattagtt ttttcatctc gtatccatct cctaaaaaat
    14821 agaatagttc ttatagttat tcataagaca tattttttcc gtttttgttt tatcctttct
    14881 gtcctataac aacttttttc aagtaaagaa tgacatagtt tttcttaaaa aaacagtctg
    14941 tttttttcta tttcttcggt gtataataaa tatgagtgtt cattttttat tttaatacgc
    15001 actccgtaca taataaatct tgatcgcatc aatcttttga gcttcttgat ctactttcaa
    15061 ttgaagtaat acaaattgag taaccttatt cattgtttct tctccaaata acaaatattg
    15121 atccggattc tctatatctt gtgtcacctg gtaaagtttc ccagttgttt tcatttgtac
    15181 atgcgggtct acatcaatac tattgtcttt aatacaacga tctgtcatat agtccctcac
    15241 agcttgattg cgtttataaa catctgtgaa attactccat tttctagcaa aatcttttaa
    15301 gaaatttttt gtcatttcat ctatttgcat ttgttgcgct gtctcgtctt ctaatgaacc
    15361 aatttgactg ttactttcag tactttgaag agttccactt gtttctttta ctgcttcgat
    15421 tgtttcttct gtcgttctca attgtgtttt ttgtttttca gaagaaaacc aatgacaacc
    15481 agtaagacct atcaaacata accaactaaa tactaaaatt atcccttttt tcacgtttct
    15541 agtcactgcc tttcttattt caccttacga accagactac gaatttttgt ttgattgtac
    15601 gtgcgttgat accgagccat aatccgtcct tgctcggcat tctgttccac actagagaaa
    15661 tgttgtccgc catatgaaac atctgttata attccggtgt gaccatagat tccaggagac
    15721 aatgcaccac ctgcttgcca attcaccaca tctcctgctt gtaaatcact tggttttggg
    15781 ttcatgatta cttgccaacc ataggttgtc cagttataat cttcccctat taacatcgca
    15841 aacatgtgtc cagaacccat taactgtggg ccacctaatt gagatacata ccatgccgta
    15901 ccaccataac attccccatt atttacggat cgtccaatga tccgatccaa aaccttcgca
    15961 ttgcctttac tttttcctgc aataagcgaa gttttttttg ttggtaggct attccaatgc
    16021 ttgatcgcaa aagtatcata ttccgttaag ttataggacg ttatgatact cattgctcct
    16081 cgataatacg gactcccttc ggtaatacct gctgccgcat agcctccacg acctagaatc
    16141 aataaacaac ttccaggatc tttattgccc acacattgat taaagttgct ttggctcgcc
    16201 accataaagc cataatagtc ataacaagct tttaagttcg gaaacttcat atagaaacca
    16261 ccttcagaac caccaattcc acgtgcagaa ccttgtgggt agggacaacc aggaaaccag
    16321 gtaatcccaa aaaagttcgt atcgtttctt ccagattgtg actgtccata agctgattca
    16381 tagcctaatt gagaaagaat cacactcggt aataactgat actttacagc tgcaccaact
    16441 gctgcttgcg catgttcatc tgtgattgga ccacgtcctt taatctctga aaaaatcggt
    16501 aatccttcgg tatattcccc attaaaagcg acagctagac ctgtagcttc tcctccatgc
    16561 tcagaaagtt ctcctgaaaa aaagaatggc aatagaaaaa agggaagaat aaagaaaaga
    16621 agacaaccta gacacccttt cttcatttct tcctcatcct ttcttcgata atggtttttg
    16681 gactgttcgt ccttttggta aagtaaaatc agttcctggt tttgcgtcca aaatcggcag
    16741 tgttttagga tccttttcta ttttttccga ttgctctgtt ggcttatcta aagaagaaaa
    16801 tgcaggttgt aacgattttg gtgcggaaat cgacggttta ctttcagacg aacgttgccc
    16861 cggttgttgc acagaacgat ttcctgatag agtggctacc gacgaattag gaacagagta
    16921 ttggttcaat aactgctgca ttgctggata actcccattt ttcgcctgat ttttcacttg
    16981 gcgaatctgt tgtgaaagag aaccagcagc tgttaattgt ggcacgggta cttttccaga
    17041 aggcaacgga atcgattgac caacaaaagc gataccttta tttaacaatg gttttctttg
    17101 attattccct tgttgcttac tcaattgtgc caatgattgt acctgttgtt ttggtcttac
    17161 tgaattcatg gacgaatttg gaatcaaacc atttgaaaga ccagaattcc actctgtttt
    17221 cgatttggta gaagacattt caggctctac cccatgataa cgaacatgac gaccactata
    17281 aggcaaggct tgatttgaac gcccacctag ttcaaaggga ttaaccactt gcctcccttt
    17341 taccgattct tgtggtgtac gtttttgttg aaacttttga aatccatgta tcgctgcaga
    17401 agcgagtgga ttcgttgctc gatacacatt ccctgctaat cctgcacctt tgattgccaa
    17461 attttgtcca gcagttgata gttgaccagg cagttgtttc atttgagaca aagaatgact
    17521 tgctatgttt ttcgtgttgt ttatagtttg atctgcagct cctaacccta gtttctttaa
    17581 taaatctttc cgttttacaa tgagtaaaat tgataggagt gctttgacaa acatatttcc
    17641 taaaaaacca aaaacagtat tcattggaat taaatcgtct actatgttat agatcaaaaa
    17701 tgccaccaaa ataatcacac tgtaaaaaga tttttgaaac atcaagccca aaaaggactt
    17761 taaggtattc atgagcatat aatcaaatac tggaacaaaa gaagcgagta atgaaaaagg
    17821 aatcacaagt aataaacaca acaccaacat ttgaaagata aaacgaatca tgccaatcac
    17881 tacaagtggt aatccaatac ttagattaag caatggcacc atagaaccaa cgactgcttt
    17941 ataaacagct ttagttggtt gaatatagac acgataagcc ttctttttcc ctctatcttc
    18001 tcctgcagca gtggtcactt ttgtctcaat atcagataat tcttcacttg acgcttcctt
    18061 ggctagaaat tcttgtggtt caatctctgc ttgatacaat tcttctaaat ttgttgtccc
    18121 ataatttaac aatatatacg gatcaacaac agccgcttta taataaagtt ggcgcacttt
    18181 ttgaatggct tccttttgtg tcgttggcac taaaacacca ttgacatctt ttgtcgccaa
    18241 ttcatctaga ctatttgtag cagaaaaaat aaagccttct acctccacgg acaaatcatt
    18301 taaccctttg gtaaaagctt ctcctttact aggtacgtta ctaccatagc caaaccaaac
    18361 cattgaaaaa atgacaacga agagaaatcg aataaacacc atttttgcgt aatgtttccc
    18421 tctaaatata cgaagagtaa atagatataa cacatacaag acgacaatcc ccgcaccaat
    18481 aggatcgtat atttttgaat aaatagtatc cgaaaaagtg aaaaactggt gaattaactc
    18541 gttcattgca gctccttcat agagcttctc aatgacaaaa tcaaggcctt gccaaatcaa
    18601 tttacttaaa ctaaagaaca tattcgtcat catttttaga aaatctgtgc catttgcccc
    18661 aaataacatt ttgcctaatg aaaattcact atcagataaa taagaagaaa aggtatcaat
    18721 atgaaatttc ccaatctcat agatcgattg atccacctgc ttttctgccg catacaccaa
    18781 tccaccaaca aaaagcagtc cgaatccaat cgttaaaaaa aacaaaacgc accatttctt
    18841 ttccttatgc tttatataag ccattgtttc acctcatttc tattgcatga ttaacgtatc
    18901 ctgttcttct acttgagagt gacttgtttt ttccgttgtt tgtaatgcag cggtcatttc
    18961 ttcaaacaaa ctgtgtacat tgagttttcc tacacgtcca tagggatcta acatccaaca
    19021 ctgtccttta atcatgtggc tcatttcagc taagttcgct tcatttactt ccaaacgtaa
    19081 atgattcaaa atcttttctc gctcactgtc ttcatcaaaa gcaaagacga caccaaaatt
    19141 ccctttttct ttatctgaac ctaagtcacc aataaattgt gtatctaaca ctaattgatt
    19201 catctgggaa cgccccacac gtgccattgc tgcaataata ctacgtcctg cgttcgaatt
    19261 attaaatacc catgcttctg taaaataaat cgctgttttc ttactactat ctcgttttcc
    19321 aaacatttca caaaaacgac ctaaactaat catcaaacac aaagactttc gatccgcatc
    19381 tgtatatagt tctggtcgga cattgtcatt tggtaatttc aaatcttgga tctctaaaat
    19441 cgttgttttg gcattaaagt ctaatcccgg gttttctcca taagaaaatc ctaaacgtaa
    19501 aatcgaatct tctaccgtca agcgtaaaaa ctcaccatat tctcgaacct ctttttgttc
    19561 catttgttct aaatagtcga ccacatgcat caagccaact tgttgtccgg cttctttttg
    19621 aactaaaact tcttggattc cctttaatac cgcccctttt aaaaggtgat tggtacctaa
    19681 cggacttaac tcatcaatca tatcctgggc tacttgtttc gcatctactc gggataaaca
    19741 aacaattgga tctaatacac cataattacg gggatttgta gcatctaacg tgacataact
    19801 cattttttgc aaatgttcta caaacaaagg gtaatgtttc tgataatacg ggtcttgaat
    19861 gagtttcgta aaccatttgc gcttttctcc tttgggatcc acaaataaac tttgtacatt
    19921 cataaacgaa ctatacaaaa agagcaagcc aactaaaaag gtcttccctt taccggtttt
    19981 tccagttact gctacatgag gcgcatcaaa caacgcacct ttgattcctt ccgcaatggc
    20041 tagaagattc aaaaagacaa aacgatttga cgcataaatt aattcttcta atggtgtttt
    20101 ttctcctcga gaaccaccat cccctaatgt atcttgccga ccaatatacc agccggattc
    20161 catacctaat tctgatactg ctgaaaacaa ccattcgcca actgcttcta cagttgttcg
    20221 gtgcttccaa tgtaactgcc gtcccaatgg ttgccctaat aaacatttat agaacaattc
    20281 tcgttgatca ttttttgcac ggtggatatg gataatcgta tgaagttgtt gaataaccgt
    20341 tgcactattt tgacgaactt cttcaaccgt ttgaccgtat acaataaaac atgcgatcca
    20401 atcgacgaca ggttgcccat tatctactcg ttgctttaaa tgttttacta atcctcgaac
    20461 agttaataag cgttcactag gttcttcatc attttgaacc aattccttat gctctgtttt
    20521 gaaccgttcc gatagccaat tcagttttaa accaatacct ccctgtcctt tcaagcgtgg
    20581 atagtgaatt ttcattcgca attctgctgg gaaagaaaga tcctgagcaa attgaaatag
    20641 atcacaattt ctcatatttt caggtgtttc cccaataggc aacaatgcta aataactact
    20701 ccctaactca tcttctaatt gaagaaggcc tttatgttcc ttcggtatac gtacatacgt
    20761 tccttgattg tctttcagta cttcccaatt attttgttct tctactttgt gagccattcc
    20821 tcgaatatat tgcagacgat tgagatacaa cagctctttt tttactaagg gacgaataga
    20881 aaagctataa agtaattgtg tcacttcttt tacataagga tcactttcag aaaacaaagt
    20941 ttccaaatca tctacttcta atccaaataa gcgtgctaaa cttcctgcta aatctaacca
    21001 gattagattt attacatcat gaaaactctc caccgttgct ttttctttga ctttgattcc
    21061 taaaataaat gaaggacgat agacttgacc ttctcgttcc aacaatgtca ctgtttcttt
    21121 tgcataatac gcaccaattg cttgactatc gggagaaaat ccctttccta atgtgtcaaa
    21181 cttcgtccgt aaattcattg ttcgtggata catcaccaac tccacatctt cataatctgc
    21241 taaaagcaac agtaaacgag ccatcatttc ttttatttcc tgtgtctttt ttggtgtgtt
    21301 ttttgaaatt gttcgtggaa aaacatgata gtaggcccag atacaatcct ctccatttaa
    21361 caaacaattt ttcttgaatg cttttactgg ttcttttaca agcaccaatg aatttcacct
    21421 cccaataaaa aaggaacaac cagttgattg tccctttttc taatcctcta aataaacata
    21481 cttattcaca aaaagtaatt cttccaatgc attgtttgat accttgtccc agttataata
    21541 cacacaatca ccattcatca tacgaatcat ataacaaaac caatcccata aataaaaatg
    21601 cacttttttt ccatcaggtt ttagttttgc cagtgctaac acacataaat aggggagtcc
    21661 tatataaaaa acaactcctg ctggtggaaa aaaagaaatg acccaaccaa taaatgaacg
    21721 taaaaataaa tattcaaaga ttacgaccaa caaaaaagtt gctgcattga cta
//
LOCUS       DAZKNV010000048        20708 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000048 DAZKNV010000000
VERSION     DAZKNV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.048"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            59..949
                     /locus_tag="ACG8M1_001986"
     CDS             59..949
                     /locus_tag="ACG8M1_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFQ0422667.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(1022..1846)
                     /gene="nadE"
                     /locus_tag="ACG8M1_001987"
     CDS             complement(1022..1846)
                     /gene="nadE"
                     /locus_tag="ACG8M1_001987"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFQ0422668.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1858..3330)
                     /locus_tag="ACG8M1_001988"
     CDS             complement(1858..3330)
                     /locus_tag="ACG8M1_001988"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFQ0422669.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3967..4329)
                     /locus_tag="ACG8M1_001989"
     CDS             complement(3967..4329)
                     /locus_tag="ACG8M1_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFQ0422670.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4552..5304
                     /locus_tag="ACG8M1_001990"
     CDS             4552..5304
                     /locus_tag="ACG8M1_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0422671.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5444..6367)
                     /locus_tag="ACG8M1_001991"
     CDS             complement(5444..6367)
                     /locus_tag="ACG8M1_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0422672.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6382..6654)
                     /locus_tag="ACG8M1_001992"
     CDS             complement(6382..6654)
                     /locus_tag="ACG8M1_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422673.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(7124..8749)
                     /gene="groL"
                     /locus_tag="ACG8M1_001993"
     CDS             complement(7124..8749)
                     /gene="groL"
                     /locus_tag="ACG8M1_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFQ0422674.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(8800..9084)
                     /gene="groES"
                     /locus_tag="ACG8M1_001994"
     CDS             complement(8800..9084)
                     /gene="groES"
                     /locus_tag="ACG8M1_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFQ0422675.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            9309..9971
                     /locus_tag="ACG8M1_001995"
     CDS             9309..9971
                     /locus_tag="ACG8M1_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFQ0422676.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(10047..11339)
                     /locus_tag="ACG8M1_001996"
     CDS             complement(10047..11339)
                     /locus_tag="ACG8M1_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0422677.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            11509..12138
                     /locus_tag="ACG8M1_001997"
     CDS             11509..12138
                     /locus_tag="ACG8M1_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0422678.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(12241..13050)
                     /locus_tag="ACG8M1_001998"
     CDS             complement(12241..13050)
                     /locus_tag="ACG8M1_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0422679.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(13105..13974)
                     /locus_tag="ACG8M1_001999"
     CDS             complement(13105..13974)
                     /locus_tag="ACG8M1_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFQ0422680.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(13975..15291)
                     /gene="yycH"
                     /locus_tag="ACG8M1_002000"
     CDS             complement(13975..15291)
                     /gene="yycH"
                     /locus_tag="ACG8M1_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFQ0422681.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(15288..17123)
                     /gene="walK"
                     /locus_tag="ACG8M1_002001"
     CDS             complement(15288..17123)
                     /gene="walK"
                     /locus_tag="ACG8M1_002001"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFQ0422682.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(17128..17832)
                     /gene="yycF"
                     /locus_tag="ACG8M1_002002"
     CDS             complement(17128..17832)
                     /gene="yycF"
                     /locus_tag="ACG8M1_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFQ0422683.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(18022..18882)
                     /locus_tag="ACG8M1_002003"
     CDS             complement(18022..18882)
                     /locus_tag="ACG8M1_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0422684.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(18869..19438)
                     /locus_tag="ACG8M1_002004"
     CDS             complement(18869..19438)
                     /locus_tag="ACG8M1_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFQ0422685.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            19819..19891
                     /locus_tag="ACG8M1_002005"
     tRNA            19819..19891
                     /locus_tag="ACG8M1_002005"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19852..19854,aa:Lys,seq:ctt)
     gene            complement(20387..>20708)
                     /locus_tag="ACG8M1_002006"
     CDS             complement(20387..>20708)
                     /locus_tag="ACG8M1_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422686.1"
                     /translation="LLALMGGMFLSSIDSTTLNTTELTSKDIDMLVNLSGNVVLFGGI
                     TLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPFFLLTLLWVIPGVLGIIAGLMLL
                     IRKS"
BASE COUNT         6056 a         4305 c         3516 g         6831 t
ORIGIN      
        1 taacttttat taacaaatat gttaatatat aagaaaaacc ttttaagagg tgatatatat
       61 gcaactacaa ataaacgaag aatccttacc ggtatatgaa gcattagcta gtaaaacaag
      121 gatcaagatc atccagctac tttccaaaaa aaagatgaat gtcaaagatt tggcaaaaga
      181 acttggagtg agcagtgcta tcacgacgat gcacgtgaaa aagctagagg aagcaaacat
      241 catcaaaaca gaaaaagtag gacaacaaaa aatttcgagc cttcgtgtcg ataaaatcga
      301 tattagtttt ccagaaaaaa tattcaatgc ttttgatacg aaagaaacat cgatacctat
      361 tggtcactat acaaattatg caattgaacc aacatgcggt ttagctacga tccatgattt
      421 tatcgggaaa gtggatgaac cacgctattt tatggatcct cgaaggatgg atgcccgcat
      481 tctctggttt accagcggat ttgtcgagta tcaggcacct aattttttaa atacagagga
      541 tacattggag atgttggaag tttctgtgga aatttcttct gaatttcctt tttcaaatga
      601 caattggcct tcagatatca ctttcagcct aaatggtgtg gagctaggaa catggacgag
      661 ccctggagat tttgctgata tccgcggtaa atatacgcct gattggtatc cagataatct
      721 taatcaatac ggcttgctga agacgatccg aattaccaaa cacttgacga atatgaatgg
      781 agaacccttg tcaaacatca cgatcaacga catccctaaa gagcaagaca cttggcattt
      841 gcgaatcgaa gtgaaagacg atgccaaaca tgtggggggc tgtactttat ttggtaaagg
      901 attcggtaat tacgatcagg atatcaaatt aaaagtttac tacagctgat atttttcttt
      961 tctattttat aaaacaaaaa cagccaatcc ctatgaaggg acggctgttt ttgctttatt
     1021 gttatttcca gaaatcatcc aaaacggaaa ttggcaaatg tcgtttatgt tgtgtcttgt
     1081 tccaccatgc ttcgattttt tcttgtgctt gagcgggaac ttcttttcct tctagataat
     1141 catcaatttc attatatgtg acacctagtg cgacttcatc tgcaatcatt ggtttcccat
     1201 cttcaagatc tgcagtcgga atttttgtgt ataatttttc cggtgcattc aatgcttgaa
     1261 gcaattgttt cccttgtcgt ttgtccaaac ggaataatgg caaaatgtcg gctccaccat
     1321 caccaaattt cgtgaagaat ccagtaatgt tttctgcagc atgatctgtc cctaatacgg
     1381 ctcctgctct ttctccagct acggcatatt gcgtaatcat acgttgacgt gctttgatat
     1441 ttcctttgtt aaaatcgctg attcccacac ctgcttcgct taatacttgt acttgtgcat
     1501 caacagctgg tttgatattt actcgcagac taacatcggg ctggataaag tcaagagcag
     1561 cttttgcatc ttcttcatct gcttgttcac cataaggaag acgaacagcg ataaattgat
     1621 agttttcatc ttttgtttct tcacgcattt cttccatcgt tagttgcgcc aaacggcctg
     1681 ctaaagtaga atcttggccg ccgctgatac ctagtacaaa agttttaaga aacggatatt
     1741 ttttcaaata tgctttcata aagtcaatac ttttacgtat ttcttctttt ggatcaattg
     1801 ttggtttgac acctaattca ttgataattt ctgtctgcag gctcatttat tctcctccta
     1861 tgcttctgta tgaagttctg ctacgctttt tttcattcgt tccatgatag ccattttatg
     1921 gttccagcat tcagtagaca gatcgactgg gtatttttgc ggattcaagt ctcgtttata
     1981 ctcttcccat agtgaatcta gattttcttt tgtatattct ttgatttcgt ttagtgcagg
     2041 taattcgtaa actctttttc cttcgataaa gatatcttgt aaaactgggc gagctgtaaa
     2101 gtctcgaaca gttttattga taaacgtatg cactggatgg aacatgaaga tagcttcttc
     2161 ttctcgaggg tcttcatccc ataatgtcac gtagtctcct tcagatttcc catcaaaatt
     2221 tcgagtgatg cgccacactt gttttttccc tggagtagtt actttttctg cattgcttga
     2281 taacttgatc gtatccatca tttttccttc atcatcttcg atcgatacta gcttgaatac
     2341 tgcaccaagg gctggctgat cataggctgt gatcaatttt gtcccaacac cccatacatc
     2401 aattttagct ttttgcatct ttaaattcaa aatcgttgct tcatccaagt cattcgaagc
     2461 atagattttt gcttccgtaa atccggctgc atctaattgt tcccgaacac gcttagatat
     2521 ataggccata tctccactgt cgatgcgtac gccttggaag ttgattttgt cacctaattc
     2581 tttcgccacg cgaatcgcac ttggcacacc tgatttcaac gtatcataag tgtcgactaa
     2641 gaacacgcag tctttatggg ttttagcgta ggccataaat gcttcataat catttccata
     2701 agattggact aacgaatgag catgggtccc gctagctggt atcccaaata tcttcccagc
     2761 acgtacattg cttgttgcat ctgctccgcc gatatatgcc gctctagttc cccagactgc
     2821 tgcatccagt tcttgtgccc gtctagttcc aaattccaat agtggatctt ctccgatgac
     2881 agatttgata cgagctgctt ttgtcgcgat caacgtttgg aaattgacca tattcaacag
     2941 tgctgtttct actaattggc agtgcgctaa aggcccttcc acttggatca atggttcatt
     3001 tgcaaaaact agttctcctt cacgagcaga acgaactgtt gctttaaatt caaaattttg
     3061 taaatactcc aaaaaacctt caggatagac ttctaatcca cgcaagtaag caatatcgga
     3121 atcattgaac gtcagattct ctaaataatt gactaaccgt tccaatcctg caaaaaccgc
     3181 gtatccgtgg ttaaaaggca tttctcgaaa gtaacattca aaaacagcat gtaaatcagc
     3241 tcgacctaat tcccagtatg tctgcatcat attgatttga tatagatccg tatgcagcgt
     3301 caaactgtcg tctgggtaag tattattcat cttgtattac tcctcttggc aagttttcat
     3361 ttcctaccca ttataacaaa aaaaattaat aggaaaagaa atcttccatt ttttctgaaa
     3421 aagcacatgt tttacggata tttcttgcta aaaatgaact ccatctgcta aaactatcct
     3481 ttcttattgg tatttaacct aaacgagaaa gaatacttat tttattcaat gtatccgaga
     3541 cacgaagaaa ttagcgtttt ctatttttct tacttgataa aataagtaga ttttcctact
     3601 acaatcgtag ccgttaagat accgatgatt gaacaaatat aaccaaatgt ctctacaaca
     3661 taatcaatgg caaaagtttt tgaagcaata atacgtcttt ccttttttgc ttcttatccc
     3721 caaagaaacg gatataactt attatgtatt gaattttttt ggaaaggcga attatgacaa
     3781 gatatacctt gcgttgaaaa aactcgcgga aaaaatatca cacgttttta aaaagataca
     3841 aagtaagaaa gcagctgtca atagaatgga aacaaaaatg gcgagacatc aatcagtctc
     3901 gccttgtttt ttattgtata cattagatat ggagcaggtt accataaaga tgattattag
     3961 tcgttattaa atagaatcct tcgtattttt ttgttctatc actacaatat ctttatttgg
     4021 acgtttgaat tgtattccgg cacgttctag ctcctgtttc actcctacat ggactttgac
     4081 atcttctcgt gtcattttta aaacgtgatg aatcgcatag tcgatttctt gccttgtgat
     4141 ttttttcttc gtattgatca tcacgacttg ctttttatca tatgtgtcta ccaatagcag
     4201 ttgtgttcga tctaacgaaa ataatttgta ataattaata gccgtattcc caaaaaagaa
     4261 ttccactact ttaggataaa atgtcttaat atttaaatta ctattcacag gtgtttcgat
     4321 tagcttcatc tcattcctct tttctatata gtcgatttag atccaatctt aagttatgtt
     4381 accatctttc ctagcattaa ggaatcggtt acaattgaac ctttaaagac aaaaggattt
     4441 accttttatc acttaatagt ataacataat ttcatgagaa aaaaatacaa ttttttcttg
     4501 accatctcgt tacgtaaagg attatgctta catttgtcag gaggaaaaat aatggagtac
     4561 acaataaaga aaatgtcaga gatatcagga gtcagtccga gaaccttgcg cttttatgat
     4621 gagattggac tgctaaaacc agctaggatc aattcttcag gttatcggat ttatggcaaa
     4681 aaagaagtcg atcgtctgca acacatctta ttttatcgaa caatggcatt caagttggat
     4741 gatatccaag aggtcttaga caatccatct tttgaccacc agaaagcttt aatcaagcat
     4801 cagcaaatgt tgctggaaaa acgggcacaa atcgataccc tcttgacaac tgtccaacag
     4861 acacttgata tgtacgaagg aggaagaaaa atgagtgaca aagaaaaatt tgaagggttt
     4921 aaacaacaaa agttgaaaga aaatgaagaa tcctatggac aagagattcg acaaaaatac
     4981 ggaaaaaaaa aggttacagc atccaatgaa aaatggatga atatggataa agaaacgtat
     5041 gaagaaatgc aaactgttga aaagcagatg ttatttgatc tcactcttta cttaaaagaa
     5101 ccagaagatg aaagcttagc agaccgtatc ttccaagctc ataagaagtg gttatcttac
     5161 agctggcctg aatatcagcc aaaagcgcat aaaggactag gaatgatgta cgaagccgat
     5221 gaacggttca ctgcatatta tgacgagcga agtggtcatg gtgcagcaaa agctttaaat
     5281 gaaattatcc aaaaaaaggc gtaatctttt acatgatcca acaaaaaagt acacgtaaaa
     5341 tgacctaata acaaaacagc agacacccaa gttagatttt tatgctaact tttggtgtct
     5401 gctccattct ttcacaagtt ttttcatcct actttaaata tattcatcgt tgaataaacg
     5461 tataaggtat tttcacttta tccttttttt ctgtaagaaa caattgaaat gccatttctc
     5521 cgcaagcttc cagatggtgg tcgatggttg ggaaaccaag aagctcgctg atcagcaaat
     5581 tatcgcgtcc aatcaccact ggtgtcttat cttgcagata gctttgcaag atgcctgctg
     5641 caaccatatc cgaatttgta aagacaccat caactccaag ctctttaaaa aagaagcctg
     5701 cttgttttcc tttctctgca tctatacaat cccaaaaaac aagtgattca tcaaaagatg
     5761 gaaaaagttg atgacatagc tgcaaagtga tttttgagtt ataacttagc ctgccacttc
     5821 gccccaacgt gatgcccaat tgctttatac cttgctgctt caaataagta agaccttctg
     5881 taattgattg ttctcgatca ataaagacac agcttgcctg ttttcccttg atttcttcac
     5941 aaaaaactag aggtccatat ttttgatatg ccaataaatc atctagtgta ttggcacgag
     6001 acgtaatgat caatccatcg aaagctttag ctgcaaattc ttcaagatac cttcgctctt
     6061 tttctttctg atagcccgtc ggtaaaagtg tcactttgta atcataatca aacgctgctt
     6121 caatgatccc actgatcaac tgatcaaaat acggatgatt ggtataaggc agaatcactc
     6181 caatgctttt cgtttttcca taacttaact gtctggcatt tgcattaggg atataatcga
     6241 cttctttcat gaccgcaagt atttctttcc ttttttcctc atctacatat ggatgtccat
     6301 tgattacacg tgaaatagta gaaactgaat aacctgtgag ctttgcgata tctcgaatgt
     6361 ttgccactgc tgcttcgcca cctatacaaa aagattttct tgtaaatagt ctaccacagc
     6421 tggaccgcat tcaaaaaact gatacatttt tccttcatgc gaaaaactga tccgctgccc
     6481 gccccaatat atatcttttg tcaaattttc gatttcattc attggtattt cttttactat
     6541 attcctattc aacccttgaa aactgtacaa cgttaatacg gatcccttga actcgacaaa
     6601 cgcataaaaa taattgttcg ttgtgccatc tgttatctct acataagtat tcattgcaag
     6661 ccctcctttt gatactttga gtatagtgta tgaaacgcgt ctcatagcaa ggagtttgtt
     6721 ttgccaaaga aaagttttat tcctctttca ttattaccaa agtctcttat tttaaattga
     6781 atacattata atgatactgt aaatatatct ttattattag tgaatggata tttactttta
     6841 atagataaaa tattataact attaaaaata actattttca ttataattac acacaaaaaa
     6901 gagcgtgaga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacagcg
     6961 gaagcagaag caactccttc ggaaataagc tgaaattcac aaaaatttga aaagcaattt
     7021 ccgtgaattt cttcttattt cttggagtta aacgcttctg ttccagcctc tttttatctg
     7081 tctttcacta atgatcagtt gtagataagc aagttgcttt ttcttacatc ataccgccca
     7141 tcattgatgg atccattgca ggagctgctg gcgctgctgg ttctggttta tctgcaacga
     7201 ctgcttctgt cgttaataac aaggcagaaa cggaagcggc attttgcaag gcagaacgtg
     7261 ttactttagt tgggtctacg atacctgctt caaccatgtt tacccattct ccagtagcag
     7321 cattgaaacc agtgcctagt tccacgttct tcaatttatc aacaatcact gatccttcat
     7381 aaccagcgtt ttcagcgatt tgacgaattg gttcttctaa agcacgaaca acgatcttga
     7441 tacctgttgc cacgtctcct tctgcttcta cagcagaaac tttgctgata acgttcacta
     7501 gagctgtacc accacctgag accattcctt cttctactgc ggcacgtgta gcattcaatg
     7561 catcttcaat gcgtaatttt aattctttca attctgtttc agtagctgca ccaactttaa
     7621 caacagctac accacctgct aatttagcta agcgttcttg taatttttcg cggtcaaaat
     7681 cagaagttgt ttcagcaatt tggtttttga tcaattgcac acgagcttcg attgcttctt
     7741 tttctccaga accttctacg atcgttgtat tgtctttatc tacaacaact ttagaagcat
     7801 ttcctaagtt ttcgattgtt gcatctttca attctaaacc tagatcgtca gtaattactg
     7861 taccacctgt caaaatagcg atatcttcaa gcattgcttt acgacgatcg ccgaaaccag
     7921 gagcttttac agctactacg ttgaatgttc cacggatttt gttcaataca agagttggca
     7981 atgcttcacc atctacatcg tcagcaataa tcaacaatgg acgtgattgt tgcaagattt
     8041 gttctaacaa tggcagaata tcttggatgt tagagatttt tttgtctgtg atcaagatat
     8101 atgggttttc tagaacagct tccattttgt cgttatctgt taccatatat tgtgataagt
     8161 aaccacgatc aaactgcata ccttctacaa catctagttc tgtttcgatc ccttttgatt
     8221 cttcgattgt gatgacaccg tcgtttccaa ctttttccat tgcatcagca atcaaatgtc
     8281 caactttatc agaacccgaa gaaacagctg ctacttgtgc aatggcttct tttgaatcaa
     8341 caacagttga gatattatgc aattcttcga ctgctgcttt tgttgccaat tcgatcccgc
     8401 gacgaatgcc tagaggatta gcacctgcag ttacgttttt taaaccttcg cgaacgattg
     8461 cttgtgtcag aacagttgct gtcgttgtac cgtctcctgc aatatcattt gtttttgatg
     8521 ctacttctga tacaagtttt gcacccatgt tttcaaaatg atcttctaat tcgatttctt
     8581 ttgcgatcgt cacaccatca tttgtgatca atggagagcc gtaagatttt tctagtacga
     8641 catttcggcc tttaggtcct aatgttactt tcactgtatc tgctaattta tctaccccgc
     8701 gtaacatagc tgcgcgtgcg tcttctgcaa atttcaattc ttttgccatg attgattcac
     8761 ctcattgatt atttttgatt atttttttat cttccaaatt tactcaacaa tcgccatgat
     8821 atcttttcct gcgacgatca gatattcttt tccttcgtat tttacttctg taccggcgta
     8881 tttttcgaac ataacttggt cgcctgcttt tacagcggca ggaacttttt caccgttttc
     8941 taacaaacgg ccttcaccga ctgcaacaac tgtcccagtt tggggtttct ctttagcagc
     9001 agaagctaaa acgattcctc cgacagtttt ttcttcttct tttgcgactt cgataatgac
     9061 gcgatcacct aatggtttta acacgataaa tccctccgat aactcttttt ttaatctgtt
     9121 agcactctta accttcgagt gctaacctac atttttaata atactcattc tccctctttt
     9181 ttgcaagctt ttaaatcaaa gaaaagaaat tttattctga cagctgctta ttgaaattat
     9241 gatataattg aaatcaatcg atataagctt gccttgcatg cttgttatcc cttaaaagga
     9301 ggaattacat gtctttaaaa aaatatagct tcctcagcat tttttgctat ggtctaattt
     9361 ttatctcacc cttgatccta gcttcgatag gacttgtaaa atctacgtct gaattgatca
     9421 cagcaactgc agtcatgtat atactaggcg ccgttgtcct agctattttt tattttaagc
     9481 aacgtgaacc cttagcgatc gaatcagcgg taaaaaaagc ttctgctcca aagattgtta
     9541 tttatggatt ggttggaatc tttgtcgcat tgattctgca aagcatcgct gtcatgttag
     9601 aatctgtatt gtttggcaaa gcaacccctt ccgagaatac acaaaatatc atccagatga
     9661 tcatggaagc acccgctttt attttggcga caactgttgc tggacccatc atggaagagt
     9721 tcgtattccg ccgcagtata ctggggatca tcagtcgata ttcaaatttt tgggtcggag
     9781 cagtgatcag ctctttgctg tttgcgtttg ctcataatga tggtcatctg ctaatctact
     9841 ttttcctagg tttcttcttc agcctagagt acaaagcaac tggtcggatc tggacatcga
     9901 tgatcacaca cgtaggaatg aacacattag ttgttcttgt tcaattagct gtccaaaaag
     9961 ggctagtata aacatgacta taaatactcc tgtcatccta gattggtgat tttcccaatc
    10021 taaagcgaca ggagtatttt tgttttttag tcgttcatct tttctgctgc tccatcattt
    10081 tttgtctgtc tttccttttt gcagtttgca gaatctattt ttttcaaaaa tgggaaataa
    10141 atgaaaaaac taattgacaa cacgatacct tgtaaaatcg ctgcaggcac tccgcctact
    10201 aagaaacccg agaggatcgg cggtgttgtc caagggactt ggactgctgt aaataaagga
    10261 acgaatccaa aatataaagc ggaataggta atcaatcctg aaacgaccgg tgcgaaaata
    10321 aaaggaacag ccatcatcgg gttcatcacg atcggtgtgg aaaaaataat tgattcattg
    10381 atgttgaaaa aggctggtaa aagagcaaga tttcctaatt ctctgtattt cttcgatttc
    10441 gcaaaaaccg tcataaaaaa tacagcccct aacgtcaatc cagcacccgt aaccgtcatg
    10501 aactgatcga gaaattgctg agtaacgata tgtccgccat ttgccaccgt caactcttgt
    10561 cctgaggcta agatttctgc atttgctaat gaattcgctt gcaagacggg actaaccaac
    10621 ccattgacca tcgcagatcc atgaagacca aataaccata aaaacggaac aaaaaaacct
    10681 aataaaagca caccaaacaa cgtgtctatg aacgattgaa tgggaagctg gacatatgtc
    10741 catactcctt gaacaacagt cattctgaac aaatgttgaa aaaccgctga accgataagc
    10801 gtaaaagtga ctataacaat gattggaatc aatgaagtaa aagactgcca aacattttca
    10861 ggtatcttct ctctttgctt ccaccctttc gcaagtctta ctaaacgtgc atagccccat
    10921 ccgatgatga gcccagttgt aactgctcct agtatccctt cagcacctgt ccagacagta
    10981 tctatctgag tatttagtgg ctgaataagc agtagataag cagacaaggc tgttatgccg
    11041 actggtaagc gatcgatgtc ttcttctttt gcataagcgt atgcaatggc aaaaacgatc
    11101 caaaaggcta tcacatcaaa tgtagcctgg tatacttgtg taaaatacat agaaaatcct
    11161 gttttgtcta tccactgagc gatgtaatcc acaggaaaat gagcaaataa gaaaaacagc
    11221 gagccaacaa taattattgg gatcgtgtaa gtcattccat tacgcaaagc agttaagggt
    11281 ctaagattca caacagatgt tatcattggt aaaaaggcac gatctaacca ctctttcatt
    11341 tcttatctcc ttcaacttct atttttatca atcagttttc ttaatttaac tatacccaat
    11401 gatcacgaac catgaaagga atgcgcactg agcttttcaa aaatcggatt ctttgacgaa
    11461 tattcagcaa ctgcttacaa tggacaggaa taaaaaagga ggttttttat gaaaattgca
    11521 ctcattggag ctactggcca tgcaggttca tttattttag acgaagcatt gtccagagat
    11581 ttagacgtga cggcaatcgt gcgtcatcca gaaaaattgc catcagatgt tccgtttata
    11641 caaaaggatt tatttgagtt gacaactact gatcttgcat cttttgatgt tgtcgttgat
    11701 gctttcaacg ctcccaaagg aaaagaagaa atgcatcaaa cttctttgtc ccatttgatt
    11761 gagatgcttg aaggaaccga tacacgctta attgtcgttg ggggtgcctc ttcgttattc
    11821 ttagatacag aaaagacgac tcgtatgatt gaccaagtac ctaaaaatgc acccttctat
    11881 ccaacagctt tcaatatgta cgaaggattg ttaaaattga aacaatctaa aaatctacat
    11941 tggacttata tcagtccagc ttctttattt gatccacatg gcaaacgtac aggtacttat
    12001 ttgttaagtg atgattattt acaaagaaac gctgctagcg acagtacgat cagcatggca
    12061 gattacgcga ttgcattagt agatgagata ctggatgaga aacatgaaaa gcagcacatc
    12121 agtgtagtca gtcgataata cggttatttt tttaatatgc taaaaaaata aaaatagaag
    12181 ataaaaccaa ccctgattga ttttatcttc tgctttttat atttttattg attgaactgt
    12241 ttaaatcgaa aatagctcag ttgcttcatc tggatctgta tcatagattt caaaatcatg
    12301 tccaacgcca aaatcttttt ctttcaaaac attttccatt gttaaatgag caagttcttt
    12361 catattgttt tccttgctaa gatggccaag atagattcgt ttggtccgat taccgatcac
    12421 atcagtcatg acaagtgcac cgtcttcgtt ggaaagatgt cctctatctc ctaaaatacg
    12481 ctgttttaaa ttccacggat aaggtcccat gcgtaacatc tcaagatcat gattactttc
    12541 catcaaataa ccatcggcat tttcaatgac acctcgcata taatcactgc aatatccggt
    12601 gtccgtcaac atgacgaatg accgattttc tttatggaaa cgataaaatt gcggagccgc
    12661 tgcgtcatgg gagacgccga aactctcaat atcgatatcg ccgaatgttc tgactttccc
    12721 catctcaaat agatgttttt gttccactgg tacatttcca atcagtggtt ccatcgcttc
    12781 ccaagtctgc tgattggcaa aaacatccaa atgatactta cgagccaaga cacccacgcc
    12841 atgtatatga tctcgatgtt catgcgtcac aagtattcca tctaattggt ccggtgtccg
    12901 atcaatttga gccatcaagg aagtgatttt tttaccgcta agtcctgcat cgaccaaaag
    12961 ccgttttttt tcactttcga tataaagtga attacccgaa cttccacttg ctaggatact
    13021 gattttaaaa gctggttttt cttcagccat ttgactccta cttcccttct tactttgtaa
    13081 acttttttca ttatactcgc ttttttattg atcttccact tttggtacag tattgtttgt
    13141 cacgatcgta ttgctgaaag cgttgacgct ctcaatttgg accactttat cgcttgtttc
    13201 gatcgctaca tgccaaacag gaacatacac atttttttcc cggactttca gaatacagga
    13261 ataagctagc tgacgccata aaatttttga tcctcttggt attttgttat tgatgtacaa
    13321 tgtattgatt gcttcctctt ccgtatacag ttccgtcttt tcgcgcagct gctcgatatc
    13381 agataaatgc gtctgcatgt atttcgtgat gctataatca ttatcgtttt tttctaaaga
    13441 aagaacgatt tttgctgtat catcattgaa tgggatgcct tcatactctt ggcttgcttg
    13501 gatttctagt ggttcttctt ctaaatgaga aaagtttttc gtgtacacat aatcattacc
    13561 gaataaaata ttgtctttgt tagataaaaa atcttccaag gaactactaa ttttatctgg
    13621 atcgatcacg ttcttttcag catctgaact ggataaagat ttcgtcaaaa catcaccgtc
    13681 taaaaacaca ccacttgcca gcaagccgct tttaccagcc ttgcgataat tcgctaatga
    13741 agtgctaaga ttggtctgct ccgcgctaag ataatagcct tgcttgttct cagacgaaat
    13801 cttccccgtg taagtgatat cgtcgctagc cagacgttgt tggattgatt cagtctgatt
    13861 agagcgaatg acattgtttt cttggtatac cgcgtcatga taactgctga ataaaaacac
    13921 attcaaccct aaaaaagcga cgaaaaatat ccattcgatt tttttgaaat ccaattaatt
    13981 cgcctccaat ccaggtaatt tttccagaag gtcgttagct gaataccagt tatctttata
    14041 tttcacatac cattcaggta agagatcaac gacacgattc gtttctttga cattttgcca
    14101 tgtatagcca acgatcactg aaccaatctt gttgctatct gctcccttag cttttaactg
    14161 ctggatgatt tcattcgtac ttgcaagttc tacttcttcg tctgaaggta tcggcacttg
    14221 aatcgtattc aaactggttt ggatattcac ttgcacagaa ccattcgttt caccgccaac
    14281 ttccacacca atctgtcctc tgctgtctgt cccaaaaacc gggaagcctt ccacgaatat
    14341 ccgataatcg atcgtattgt cactgcggtc aaaatatctg aggttcccta aagaactgcc
    14401 taatttgcta atatagggga aactttcaga aaatacacta gcattttctt ttttctctgg
    14461 cagctctcca cgaaaatcaa ctacttgcgt ttccgaatgg atagacattg tttcattccc
    14521 accgtaaaaa atcaattcat tgctttcatc attatttttc acgctatctg gtttctggaa
    14581 aaaagcattt ctaaaaagtg tatagggttg ctgtgacagg atataactat acttcttcag
    14641 tttgatcgaa tgtttcgtag catattgcgt gtcgatcgtc gatggttctg ttgtcatttc
    14701 tgtccatttt gtgtcttttg ctgttaattc tttattgata tctgtccaat tcaacgaaat
    14761 atttgcttca tatacgagat ggttcgaata attcaaaaat cggatttttt tatttccttg
    14821 atcgaattgt attctagtaa aatacatatt ttcgctttct tttgccaagt tcgacacatc
    14881 taaatctaaa tcaaatgctt ccttgtattc tcttagcaaa aaaggcgcat tataggccaa
    14941 ctcaaaacca gagttcagat ttttcacctg ttcaaactgt gatttgtctc ctgaaactac
    15001 ttcagaaagc tttccaaatc ttgctttatc gatgatcaat tgcaatcggt acacgagatt
    15061 ttcactgttg gtttcttgga tcattcccga atggtgccat gtaacatgaa gcggaagaaa
    15121 gacttcggaa gtttttcgat tgctttgaga ctcgatcatt tgagtgtttg tctcatctac
    15181 gttgattgaa ctttttcctg ctgggctcag ccagattgca taagagaagt atatgcttaa
    15241 cgcaaccatc aaaatgagtc ctatacgaac gactttttca gagattctca ttcccaccat
    15301 tcctcctcat aaggttcata tggcagcgag atataaaaag tcgacccttt tccttccttg
    15361 ctctctgccc aaatagcgcc tcgatgcgcc ttaatcactt ctctagaaat agctaatcca
    15421 agtcctgtcc caccttgtgc tcttgcacgt gctttatcta ctcgatagaa ccgctcgaac
    15481 actcggttca gatctttttt aggaatcccc aatccttgat cggtgatact taaaatcacg
    15541 ttattatgcg tttctaataa gcgacaagta atcgttcccc catctggtga atacttgatc
    15601 gcgttattca tgatattatc gactacttgg atgattttat ctgtatctac ttcgacccaa
    15661 agatctcttt gcgtaaattc acgacggatc ttataatttt tttcctgatt tcccaccatc
    15721 atatcaaacc ggtcaagaac aaaattcact aactcgttga aattgacata ttctaattga
    15781 agctgggtat tacctgtatc catgcgagat agatttaaga ggtcattgat cattcgaatc
    15841 attcggtctg tttcatctag cgttaccttc aaaaaatttg gtgctacttc ctcgtctttc
    15901 cacgcacctt cgctcaatgc ttcgatataa ctacgcatac ttgtcaacgg tgtacgaagt
    15961 tcatgggaaa cattagagac gaattcacga cgttcccgtt ctgttttttc ttgttctgtc
    16021 acatcatgca agacagctac taatccgctg ataaaacctg attcgcgacg gatcatagaa
    16081 aagtctactc gcaagatcat ctgatcactt tccaatgtac tggttgaacg gtcaagtacc
    16141 atttcgtttg gatcttctaa taatttccgc aacgtatatt cttcttcgat atctaaaagt
    16201 gtcaaaatcg attgtccgat tgcttcctcg tttttgatat ctagcaagga aacagccata
    16261 tcattgatcg taatgacttt acccctgcga tctgtcgcaa tgacgccgtc tgtcatatgg
    16321 gatagcacgc tatccaaacg attgcgttca gcttccattg tatcttgagc ttcttcaata
    16381 cgttcagcta actgattgaa ggtatcagcc agctgtccaa gttcatcttg tccatgcact
    16441 ttgactttcc gactgtagtc tcctctagcg attcgaatgg cttgttctct catttcaccg
    16501 atcggctgtg taatcgaacg agcaactaaa acagatacga tcattgaaat aaatgccgca
    16561 attagtgagg cagtaaagaa aatgactgct gtgttattga tttccgaata tttttgttcg
    16621 atattacttt tgacgtaaag agccccgata acggcatcgc cggtcgggga caggatcggt
    16681 tgaacattga tattcacccg tttatcgtcg ttatctaaag caacataacg tttagtcgtg
    16741 aaatcattga tatcaacata atcatttttc tttcccacag cgctttgttc attgacatcg
    16801 gttgttcctc ggatgatccc tttttcgtca acgacccgta tttcgatgat atcgctagtc
    16861 gcactgtttt caataaatct tttgatattc gcatttacct cttcatcatc tgcattatct
    16921 tttcgattca attccgggct gattgttgtt gctaatgatt ccaccgtttg attcatatct
    16981 ttaataaatg tattgatcgt ggaacgttct aaaccacgta taaagtaggc accaataatt
    17041 tcgatcgaga tcaataaaat cagaataaag gtaatagcga tcttaaaatt gactgatcga
    17101 aaaaagcgga cttttctttt catccaatta ctcctgttct gggttacgca aatagtaacc
    17161 gacaccacga cgtgtcacta aataatttgg atggcttgga ttatcttcga tcttttcacg
    17221 caaacgacgt acagttacat ccactgttcg tacatctcca aaataatcat aaccccaaac
    17281 cgtttgtaat aaatgttctc ttgtcatcac ttgtccaagg tgcttcgcca agtaaaagag
    17341 tagttcgaat tcacgatgtg ttaactcgat tgtttctcct cgtttcgtca ccatgtaagc
    17401 ttctggatgg atcgtcaaat caccaatcgt caattccgca ggtgctgcct cttctggttc
    17461 cttcgcagcc gtggcaccgc gacgaagatt tgctttgaca cgtgcaacta attctcggtt
    17521 ggaaaatggc ttggtcacgt aatcatcggc gcctaactct aagcctagga ctttatcaat
    17581 ttcagaatct ttggctgtta ccataatgat cggcatatca taagttttgc gtacctcacg
    17641 agcaacttct aagccgtcca ttttaggtag catcaaatca agtaaaatca aatcaggttc
    17701 tacctcagca actttttcca aggcttcttc cccatcatat gcagtataaa cgtcatagcc
    17761 ttctttggct aaattgaatt tgacgatatc cgaaatcggc ttctcatcat cgacaactaa
    17821 aacttttttc ataaagagcc acctcttata tattattgtc ataccttctc attataccgt
    17881 atttctgctt ttgtttcatc tttgcctata aaacaaaaga gaaaattaaa atgaaagtgc
    17941 aaaatacttt attatttttt gttctaactt caataaaaaa ggaaaacact gattttcacc
    18001 tcagtgtttc ctttttttga tttatccttc taaaacttgt acaccgacac ccaataatcc
    18061 cggaccagtg tggactacta atgccggaga aatctggcca aagtagattt ggtttgcttg
    18121 tgggaactct cttttaagtc tcgcttccat ttcaattgct tcttctttcg catccccatg
    18181 ggcaacagct aagttgaaga cctttgcatt accgattttt tctttgacgt aagcaaccgt
    18241 tttatccaaa ctttttttac gtcccctagc ttttcctact gtgtaataaa tcccttcttc
    18301 attacatgag atgattgggt taagctttaa agcggttcct acaatagaag caactaaacc
    18361 gatccgtcca cctttttgaa gatattccaa tgtcgcaaca ttaaagaaaa cttttgttct
    18421 ttcgactaac tcattcagat tactgatcag ttgatcccat tctactcctt cttccagcca
    18481 ttttgctgct tggatcgcag aaaaacctgc accaatacca atatttttcg tatctagtac
    18541 atatgcttcc aattcttctt gctgttgtgc aattaaacga accacattat atgtcccgct
    18601 caatccactg gaaattgtta ccgcaagtac cttttcataa ccgtcttttt tgatttgctc
    18661 aaagatttct gtgatcgact caccatccgg caaagatgta ccagggattt cctctggcaa
    18721 acgttgatag atctcttcag gggtaatgtc aattttatct gtatatacct gatctttata
    18781 aataattttc aatgggatca tatacatctc gtattttttt atcaattctt ctggaacatc
    18841 cgtacctgaa tctactaaaa ttgcgatttt attgtttttc atttgttttc tcctctttta
    18901 aatattcggt ttctagaaca atcgtttttt ccgcaagaag tttcattgca aacgataaag
    18961 ttgccgctct tacagcaata tattctacag gggttgcctg gtcgaatttt tgcggatgag
    19021 atttaccttg tgctaattgg ctgaccatcc acacagctgc ttcttgttca tcgcaaaata
    19081 gattataggc ttcacgaatt cctactgttt ttccttggaa caatatccct tctttgattt
    19141 caggaatagt caatacttgt ttcaacgtag tgattgcaag taaaaatgct acgtgttctt
    19201 tgttatatct ttttttaact ggtgctggta tcaaacctag tttaacgtaa ttgtttacca
    19261 tagaagaggt aagcaatgga tgcttttctc cttgtatcac aggtgaaaga taacgatcaa
    19321 ctaacgttct gacttggtcc atataaagtt ctaagtcagg gagttcttcc cagtgaggca
    19381 gacggaatgt ttctagttcc ttcccccact ccattaattg ctgacgcatt ttttccatca
    19441 taaccgctcc ttttttcatt tcataaacat gatatcagac ttatgataaa cattcaatct
    19501 agttgcttta actaggtgat ttgattagcg ggattctatg aaaacaaaaa acaagaaggc
    19561 taagccttct tgtcttttat cgttaagaac aggagacccg ccggggagac ggcgggaaag
    19621 gagtaaaaaa tgaaaaaagt gttagggttt gttctcttgc aagaactttg tttgttggta
    19681 tgcttatata atagcgagca aatgtgaata atctatgaat gatttcctat aaggaagtaa
    19741 agatttttct gattttcttt aaatgtagtc ttgcatttta aaattcttag tgctactatt
    19801 attaagtact ttttgtacgg gccgttagct cagttggtag agcagctgac tcttaatcag
    19861 cgggtcgcgg gttcgagccc ctcacggccc attgggtgcc aaacccacgg aacaggtaaa
    19921 tgttggtgcg aaagcatttc gaaaacattt acgctgttct ttttttattt ttcaaaataa
    19981 ctagggcttt ttatttttaa ctcaaagtcc actgtagccc tttggacttt gagttaaaaa
    20041 agaagcataa ttatgaacag taaagtttct aatataacaa taattcgaga agctttgcaa
    20101 aatcatgctg ccaatgaact ctctaaacat ataggattaa atctaagtac tataaaaggt
    20161 taaaaagtga agaatattta atagaaaaac taaatttact tgctgctttc cccttttcca
    20221 ttaatacaac aatcagagag tgtctttttt tcgaaaaaat tagaataaat aaaagacacg
    20281 tagttttttt atctacatgt cttccatcga ctacaagtta tcatttctca aaacgtattt
    20341 agcttttaat tgattaatcg tttcacgttg tctacacatt gcctaattaa gattttctta
    20401 ttagaagcat caatcccgca ataataccta aaactccagg aattacccac aataatgtta
    20461 aaagaaaaaa tggaataata gataaaatga gtaaactaat accatagacc actgtttttt
    20521 gattttttct tactaaaaaa cctattatga aaatcattat cgaaaaaact agggtaattc
    20581 ctccaaataa aacaacattc ccgcttagat tgactaacat atctatatcc ttactggtta
    20641 gttctgtagt atttaaagta gttgaatcaa tagaagatag aaacatacca cccatcaatg
    20701 ctaaaaga
//
LOCUS       DAZKNV010000049        19645 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000049 DAZKNV010000000
VERSION     DAZKNV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.049"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(63..263)
                     /locus_tag="ACG8M1_002007"
     CDS             complement(63..263)
                     /locus_tag="ACG8M1_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0422687.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(715..1035)
                     /locus_tag="ACG8M1_002008"
     CDS             complement(715..1035)
                     /locus_tag="ACG8M1_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422688.1"
                     /translation="MKKRVLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1538..2656)
                     /locus_tag="ACG8M1_002009"
     CDS             complement(1538..2656)
                     /locus_tag="ACG8M1_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422689.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPEIEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            2889..3011
                     /locus_tag="ACG8M1_002010"
     CDS             2889..3011
                     /locus_tag="ACG8M1_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422690.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            3127..4434
                     /locus_tag="ACG8M1_002011"
     CDS             3127..4434
                     /locus_tag="ACG8M1_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFQ0422691.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGESRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANMFVIGWRRVAEFFGNLF"
     gene            4553..5752
                     /locus_tag="ACG8M1_002012"
     CDS             4553..5752
                     /locus_tag="ACG8M1_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFQ0422692.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(5779..7047)
                     /locus_tag="ACG8M1_002013"
     CDS             complement(5779..7047)
                     /locus_tag="ACG8M1_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFQ0422693.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(7102..7168)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(7210..7857)
                     /locus_tag="ACG8M1_002014"
     CDS             complement(7210..7857)
                     /locus_tag="ACG8M1_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFQ0422694.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(8265..8768)
                     /locus_tag="ACG8M1_002015"
     CDS             complement(8265..8768)
                     /locus_tag="ACG8M1_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0422695.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(8891..9655)
                     /locus_tag="ACG8M1_002016"
     CDS             complement(8891..9655)
                     /locus_tag="ACG8M1_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFQ0422696.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMALTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFMVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKENAESLNVGVAAGIVLYHFSL"
     gene            9763..10038
                     /locus_tag="ACG8M1_002017"
     CDS             9763..10038
                     /locus_tag="ACG8M1_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFQ0422697.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEEDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            10715..11665
                     /gene="yidC"
                     /locus_tag="ACG8M1_002018"
     CDS             10715..11665
                     /gene="yidC"
                     /locus_tag="ACG8M1_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFQ0422698.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(11844..12818)
                     /gene="lacD"
                     /locus_tag="ACG8M1_002019"
     CDS             complement(11844..12818)
                     /gene="lacD"
                     /locus_tag="ACG8M1_002019"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFQ0422699.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(12815..13273)
                     /locus_tag="ACG8M1_002020"
     CDS             complement(12815..13273)
                     /locus_tag="ACG8M1_002020"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFQ0422700.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKDVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTKIATILTKEIGEDL"
     gene            complement(13270..14736)
                     /locus_tag="ACG8M1_002021"
     CDS             complement(13270..14736)
                     /locus_tag="ACG8M1_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFQ0422701.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDASMGMMVPVLAAYIAEGIAKRPGLIVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDDSKAANRTVIEKGRAGDLS"
     gene            complement(14718..15668)
                     /gene="pfkB"
                     /locus_tag="ACG8M1_002022"
     CDS             complement(14718..15668)
                     /gene="pfkB"
                     /locus_tag="ACG8M1_002022"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFQ0422702.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIREERFERWENIN"
     gene            15811..16560
                     /locus_tag="ACG8M1_002023"
     CDS             15811..16560
                     /locus_tag="ACG8M1_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0422703.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINVLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISQKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            16826..18304
                     /locus_tag="ACG8M1_002024"
     CDS             16826..18304
                     /locus_tag="ACG8M1_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFQ0422704.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(18372..19463)
                     /locus_tag="ACG8M1_002025"
     CDS             complement(18372..19463)
                     /locus_tag="ACG8M1_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFQ0422705.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         6057 a         4025 c         3404 g         6159 t
ORIGIN      
        1 aaaatagaca aaaacgccca gacacgcaaa tgtctgggcg tttatttttt agtataggtt
       61 aattaagctt tagtaacgtt tgttgcttga ggtccgcgtt ggccttcttc aacatcgaaa
      121 gttactgctt ggccttcttc taaagttttg aatccgtcgc cttggatagc tgagaaatga
      181 acgaatacat cgtttccgtt ttctgcagtg atgaatccaa atcctttttc tgagttaaac
      241 cattttactg tacctgtttc cataataaaa atcctccttg tgtatcaaca catattttgc
      301 aattacttga atggtgtata tctggaagat gtttatttga aacaagctac cacagattac
      361 cgaacaaaaa ctactcctat agtatatcat accgtttaca aaaaagctag agtttttcga
      421 ctttttttat taaaaaaagt tttctcagcg attacataaa gtgaaaaacc gaactttttt
      481 taaaataaac gaaatattgt tcagttggtg tttttttgct ctgatgttct tctttaaact
      541 aaaaaaatta ttctttctga ctacttatcg gttctgtttc aacggtcgag gctggggaag
      601 attctttagt aggtctgatg ttctcatggt atttctgata gcctatgaca gtgaccagaa
      661 gaacaaggca aaccaatacg atcaacgaga ttagtttttc ttttttgctc atatctatac
      721 ctcataaata acaggatgat gtccatcata tttctgagta tgagtaaaag caaaagctgc
      781 agctgtagaa tgtaagaaat gccagcaact ttcataatca caggtcggac agtaccaaaa
      841 gtaaccaaat cttggctgca aagaccgttc ttctgtttca ggaatcgcag aatcaagatc
      901 tgttgtctgt acataaacat ttttgtacag acgtgtgcct gtaataggag accgctgtgt
      961 ttcttcagca aaaactggct gacttgttaa acttagggat agaaacagca aacaccataa
     1021 cactcttttt ttcataaaga cctccttatc gataagtttt tcccaattaa aatcatatct
     1081 caagaacgcc cgttattcac attttgttca taaatgatgt tttttgtatc ataatcgtca
     1141 aaaagaggtc gtgaccacgt cacaacctct tttttaaatg gtgttccaga agtagcttct
     1201 tcggaaataa gccgaaattt cacaaaaatt tgagaaataa tttttgtcaa tctcttctta
     1261 tttcttgaag ctgaccactt ctgtcacaac ctcttcctta aacggtgttc aaaagcttgc
     1321 atctgcggta ataagcccac caaacaaaaa atatgaagag ctatttttgc ttgctgttct
     1381 tattacttga tgcagaacag ctttttcaca acctctcata cacggtgttt aatcagctga
     1441 ccttcggtat tagctcaaaa aacggcaaaa tatgtgaaac tatttttccg tttgtttctc
     1501 taatactcag gtcaaaacac tgttttcaca acctctttta ataacgaaga atcgctgtca
     1561 gactcttttc atctggcgca tctttttgat ccaaaataaa cactttcccg ccattaatga
     1621 tcacatcatc tgctaatgca ttcaacactt gacgccgatc atattctatt tcaggatctt
     1681 caccgaaacc atcagctaag tttgacgtag cgataaatag atgcgacact tttccttctt
     1741 tcgcagctgg aacgatatca actaactgat cgatgaattt cttatctaag agtttattgt
     1801 attcttttga ttcttgagct gcgagttcac ttgacagctt cttcgcccct tcttcgatat
     1861 ctctaaagga tagctgcgca ggagaagcag aaatcgcaac gtctgcacaa taatagggat
     1921 ttttagcaat ttttttgaac atcgtctgat tttctggtaa tgcaaataaa taaatcggcc
     1981 attgttctgg attttcgaaa gaatccttca agtacgtatc aacagcttgg taatagttga
     2041 cccaatcgat ctctacttct tcatcttttg gatttacgcc atggaaagtt actccatctc
     2101 gggctccgcc tcctccatta gaagagaagt tcaaaccgcc acctgtcagt tcagatccca
     2161 atgcagtaac gacatcaacc ggtgcccctt ctggtagaga tacttctttt acttgtttgt
     2221 tgctgacttc atacaatttc atggagtcgc ggttcaatcc caacagataa taggaatagt
     2281 tgaactgtcc atttttgata atggccagta aataaggaag atcacttaca tagtattgat
     2341 cgtctaccgg gatactcaaa cgatggatat aggtttggtc agcagttata atgaccgcta
     2401 cactcgtagt tgcactacgc caaaacgaag gatctcctaa caaattttca attttttctt
     2461 ggaacgggga ccagtcatgt tcggaatatt ttttctcaaa acgtttcttt gcttctttcg
     2521 caaaattttt gaatttgatt tgatcttttt ccacatcttg atgggcgaca tgcgtattca
     2581 gcatgatcgt gacgaatggt cctttagcgc cttctgaagt caattgtgac aataattctt
     2641 tatccttttt tgccataaac gtacccctcc taaaaaaatc attcctttgt ttctatctaa
     2701 agtctaccac aacactattt ttccatacaa taaaacgtat ctaaaaaaat aaaacggttt
     2761 ctacggtttt aaatttagct atttttttaa gttatcttca taatttcctc aattatttag
     2821 ccccagtctt caactattct tcatgaaatg ctgataaact aaaaaaaaga ataaaagagg
     2881 tggatcttat gcatttgatt atgattttca gtttattaag tattatcagt ttatttgctt
     2941 tcagcgcttc ccgcttatta gatgcggaaa cacagcctat tcctgtaaaa gtacgtaaaa
     3001 acgaccgcta accttccata acgtgcgttc ttatcctaaa gttttttcag aaacattgaa
     3061 actctctccc ctctctgata aaattttaat ttgtagcgaa acaaattaat tacaaggaga
     3121 tcggatatgt ccataaaaaa aacacgtcta gtcctattat tggctagtct cattctttgc
     3181 cttgcttctt ttctaccagc tgttgctgtg caagctgaag atacgttcaa agtaaatgca
     3241 aaagcagctt ttgctgtaga tgcgcaaagc ggtaagattc tttatgatca agatggagaa
     3301 aaaaccatgg ggatcgcttc aatcacaaaa atcatcggtc tttacatcgt tcttgatcaa
     3361 gtaaaagaag gaaaactatc atgggatgat aaagtttcga tttcagatta tgcagaaaat
     3421 ttgagtatca ccccagattt atcgaatgtt cctttgcata aagaaaacac ctacactgtc
     3481 aaagaattat tcgactctgc aatcatccag tcagccaatg cttcaatggt ggccttggca
     3541 gaaaaaatct ctggcagcga agctaaattc actgaacgaa tgaaagaaca attgaaagat
     3601 tggggaatca aagatgcaac gatcgttaat gcatcaggac tgaataactc ttatcttggc
     3661 gaaagccgac cagaaggtac tggagaaaac gacgaaaatc aaatgtctgc tcaagatgtg
     3721 gccatcgtgg cccgtcattt gatcttggat tttccagaaa tactggacgt atctagcact
     3781 acgacacaaa tgtttggcga aaacacgcaa tcaccagtgg aaatggtcaa ctggaactgg
     3841 atgctcccag gattcgttaa ttacaaggaa ggcgtggacg gattaaaaac tggtacgact
     3901 gagcttgcag gtgcttgttt cgttggtacg atcactaaaa acgatcaacg gatcatcact
     3961 gtcgtattga atgcggacgg ccatgcggaa aacccgagtg cccgcttcaa tgaaacagac
     4021 cgtttgatgg actactgcta tgacaattgg tcagaaaaag agctcggaaa agctaacgca
     4081 agtattccta gcctaaaaac cattgatgta aaagacggaa aagaatcaac agttcctgtt
     4141 gtgcttaaaa gccctgtaaa agtatgggta cgaaacgata tggatactgg caaattaacg
     4201 atcacgccaa cacttgacaa gaagcaagtc actgacaacg agatccaagc acctatggat
     4261 aaaggtacaa aaatcggtac cgctacgatc accttggcag acgataaatt aggctattta
     4321 gaagacaaca atgcgccatc aacagagatc attacggata aaacagtgga aaaagcgaat
     4381 atgttcgtga ttggctggcg acgcgtcgca gaatttttcg gcaacttgtt ttaattgaac
     4441 aataagaaaa gcatctttcc atcggaaaga tgtttttttg ctttttctag tttaaataac
     4501 agcttttttc atctattttc gttatactgt ataagaaaaa ggagttgaat ttatgaatct
     4561 aaccagagat ctgatctttt tagttctcta tcttattggg gtattctcta tcgtttattg
     4621 gcgaaaacag aagaaggatc cttccttgtt cttttacggc agtacgtgga catttacggt
     4681 aatcttaact tattttgtcg tgttggaaat tttttattcg accttttatt ttttgattcc
     4741 attgttgttc tttagtatct ttgctttttc ttatttcaca gaaaaacgaa ggctgctgaa
     4801 tggtctttta ttcaatgttt tcctcatcag tttcggcatc tacttgtttg tcttgctgta
     4861 tgaaacgcaa aatattttcc ttggcggact gatcgccttg atcacgattc cattgctact
     4921 tgtcctttta tttggtattt atggattgat tgtttttctt ttttggaacg gggtcacagt
     4981 tttacgtaga gaatcgcatt cattagcgaa tcttttaacg ttgatactag ccatttttct
     5041 tacactgttt cttgtttttg actttttctt gttaaaatat ttgccgcaat ggataaatgc
     5101 tttgtttttc tgcgttcccc tgatcttgat ctatctattt atcgtattct acaacttttt
     5161 gactgtctca ttcttgtacc agttcaaccg gcctcgatac aatcaagact tcatcgttgt
     5221 gttaggcgct gggttgatca atggagaaac agtttctcct cttctagcca agcgaatcaa
     5281 taaggcaatt gctttttatc gggctcaaag ccgtgctaca ttaaatccgc ccatcttatt
     5341 gatgtctggc gggcaaggag cagacgaaaa agtaccagag gccattgcga tgaaacaata
     5401 tgccatggaa caaggaatcc ctgaaagaga cattcttgtc gaaaccaatt cgacaaccac
     5461 tttggagaac atgctctatt caaaggaaat catggatcag caaatgaaag ggccataccg
     5521 cgcgatcttt agttccaaca attaccacat ttttagagcc ggtctttatg cgcggcaagc
     5581 caaattgaaa gcaaatggta ttggtgcaaa aacagctttc tactacttgc ctaatgcgtt
     5641 tttaagagaa tacatcgcca tcttgatgat gaacaaaaaa agacatatga tcatttgcgg
     5701 attgcttttc gcaggctccg cattcttatc gctgattact ttacttttct aaaaaaacaa
     5761 ggtgtgacaa aacatatgtc acaccttgtt tttttctttc attctcttaa ctattggcaa
     5821 aaagagtatc ccttttttga ccgctacttg ctgagcagaa taaataccgc tgttgcctga
     5881 acacataaag ctgatcaagc agatcataaa gaagtaaaca gccgcttgtg aaccgaacaa
     5941 ttcgatcccc atcacaaagc aggcaatcgg tgtatttgtc gcaccagaaa atactccgat
     6001 aaagcccaat cctgcgagaa aaggaacaga aacatggagc aaaggcgcta gtgctgcacc
     6061 aagcgttgca ccaatttcaa acaatggtgt cacttctccc ccttgatatc ccgcgcctaa
     6121 agacaaaact gtgaagaata acttcccaat aaaatcatag acatgtgcct gtccattaaa
     6181 tgattcttga agtaacggaa gactcaatcc gagataacgt tgtgtttgca aaatcaatgc
     6241 tgctgccaca actacagccc cacctatcgt atttcgccaa acaggatgag gaatccattg
     6301 tgcataccgt gcttttaaaa agacgatcga acggctgaat acccagccaa tcaaaccaaa
     6361 agcaatccca gcaacaaaaa ctttgaagaa cagcaacata ctccattcag ggatcacacc
     6421 catttggtaa tgtaggtgag aaacaccata gctttccgtc atgaaatttg caaacagtgc
     6481 agcaaagaag ctagggaaga tcgcttctgt tcggactttc ccgattgcca acacttctaa
     6541 tccaaataat gttccagcta aaggtgtgcc aaatacagaa ctaaaacccg cactgattcc
     6601 actgataatc aagatttccc gttctgcttt atccaatcgg aacaaacgtg ctgtattatc
     6661 tgctaacgct ccccccattt ggactgctgt tccttcacgg ccaacagatc ccccaaataa
     6721 atgggtagtt atggttccaa acagtgtaag tggaataagc cgcaacggga ttttttcttc
     6781 tccaccattt ccttgatcga tcactaagtt gtttccacga ctagaaagtc cgccgtgata
     6841 cgcatagaga taagcaaaaa gcgcaccact aactggtagt agataaagga gccaaggatg
     6901 tgatagtcgg atatctgtca caactgtcaa gctatttaag aaaaaagcag acaagctccc
     6961 catgaatata ccgagaatcg ctgtgatcac cagccacttc agcatgtaca ctaaaatgcg
     7021 tactggactc ggtaattgtt tttccataaa aaattcctcc tcaataaaaa aacgcctact
     7081 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
     7141 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
     7201 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
     7261 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
     7321 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gaaacattcg atgttttctg
     7381 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
     7441 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
     7501 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
     7561 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgaa cgatttgctt
     7621 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
     7681 taaaaatgta tcgatttctg gcagttcgtg atctaatatg tctcgaatct tttcagctgc
     7741 tagtgcctga actgtttgca ccgtttttgg atcattgaca gatgagtacg catttaataa
     7801 ctgttctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
     7861 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
     7921 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
     7981 tcaccccctt taatgcttat tcttctatgt acatgattca ttcgataaat aaaagtaaac
     8041 cgtatcttga acagatagtc aactgcaaac agaaaaaagg actgtgacaa aagtcgtgtc
     8101 aaagtccctt gtttcgaatg aatggtgttc aaaagcttgc atctgcggta ataagccgaa
     8161 acttcacaaa aatttgagaa gtaattttcg taaattcctt cttatttctt gaagctgacc
     8221 acttctgtca caacctcaat atggtctatt attggtttta cctgttaaat cgaggattct
     8281 ttcccaaagt aacgttgcca tctcttacgc atacttgcag acatgggctg tgccgcttct
     8341 ttgactgcgc agtatttgtc cacgaatgtc acgatatatc cttctttata cttaggcggt
     8401 gcgatcgttg caccccacat gtgcttcaaa atgatatctc gctcaagatc cgacaaatcg
     8461 gtgatttttt ctgcattctt tacagcaatt cttggatgga tatacgcatg tgtcccctcg
     8521 tcaaatttcg tcgtacgcca atcatagtag aacagatcat gcaaaagtcc agcacgcgct
     8581 gttgctttag cattgccacc ccattttttt gcgagcagat aactatagta agaaacactg
     8641 atggaatgct ccaaacgagt ggaatgaaca tgctgtgtgt aattcgctaa ttttttcact
     8701 gcttctgttt ctaaaagatc ttgtacataa gacatatatt cttcgtcttc acgccatttt
     8761 tctgtcataa ttatcgatct gccacctttt tgaatttcat tttcttctga aattgatcta
     8821 agtataccac cagtgttcgg attattctag tcgctctaga taaaatagct aaagcttaat
     8881 agttccttaa tcataaagaa aaatgataaa gaacgatccc tgctgcgact ccgacattca
     8941 atgattccgc attttctttc attgggatat atacgttctg atcagtcaaa gacaagattt
     9001 cctgacttac tccctgacct tcgtttccca tgattatagc gaaatcctct gttttttcta
     9061 ctttgtctaa tgcatgtgct tcttcattta attctgtacc gtacaccata aaccctttgc
     9121 ctttcattac agggatcact tctgccaaat ctttttgtaa cacaggcaaa tgataattgc
     9181 ttccctgcat gcttcgcagc acctttgtac tataaatatc tgccgttcct ttacctaata
     9241 aaacaccagc cataccaaac gcatctgccg tacggatcat cgttcccaca tttccaggat
     9301 cctgtacatt atctagtaaa agccagcctc ctgaaaaatc tggcgtatct tcagatgtta
     9361 acgccatcac tgctaagatc ccttgcggtg taggtagatc tgacatagcg gtcatgacct
     9421 catctgaaac tagaaaagta gaaatctctt tgtttacagc cagccagtct ccccattctt
     9481 tcatacctct ctgtgtcaca aaaagttctt ttatttctgc atcagacgac gcagcttctt
     9541 cgatcagatg gaacccttcc aaaagatatt ctgccttttc ttctctgtat ttctttttat
     9601 gtagtttttt taattctttg attcttggat tttttgctga ttggatctct ttcacattcc
     9661 ttcacctcac ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat
     9721 cggtatcatt gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg
     9781 aatgtccaag gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat
     9841 cagttaggcg tgaccggaac ggtaaaaaac gaagaggacg gctcagtcac aatcgaagca
     9901 atcggaaatg acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca
     9961 agtggacgag tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa
    10021 tttgatgtgg tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt
    10081 ttgtgaaaat gtctttccac atttttgcat aaatttgact taataccgag aaactgactt
    10141 ttgaacaccg tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca
    10201 ttttcaaaat agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat
    10261 aaaacaccgt caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg
    10321 tgaaaaatag ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt
    10381 tgaacaccat cgataaggtt gtttttgagg cactttgcct caagtattaa agacaggtag
    10441 taaaaaagct gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac
    10501 aaaaaagttt ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta
    10561 agtatttctt tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaaagaa
    10621 tatttatatg aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa
    10681 gtttgtgtaa aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt
    10741 gggatccgga cttgtcagta tcctgctctt tttatctggc tgcgtgcgga tggattcaaa
    10801 cggaaaccct gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc
    10861 gattacatat ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac
    10921 tgtgatcgtt cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat
    10981 ccaatctgaa aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa
    11041 agctgcaaca acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg
    11101 cgaaaacgga ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc
    11161 gatcttctct gccttgtatt ttacggctcg ctacacagaa ggtatccgtg aatcatcttt
    11221 ttacggcatc gatctaggct caccaagtat ggtgcttgtt gccattgcag gggtcgctta
    11281 tctgcttcaa ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg
    11341 tacgatgctg atcgtctctc ctgctatgat cgtcttcatg tcgatcagtg cgccagccgg
    11401 tgttacactt tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa
    11461 cgttatgatg aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc
    11521 aaaacaagtc gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa
    11581 acaagcaaca aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc
    11641 aggaaagcag cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca
    11701 gttttagcaa ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt
    11761 atttaagtga atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct
    11821 ttttatgaag aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct
    11881 aatagtgtac ttaattcctt aatattttgt tttccttctt ctaacatcca actactcgct
    11941 ttttcttcgc cttcggtaac aaaaggcgcc actcccttcg cccatgttgc tcgcccacat
    12001 aagacaccat tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc
    12061 gtagcattga ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca
    12121 tagaaatacg cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca
    12181 aatctcatat tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa
    12241 aattctcgca tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac
    12301 ggatcgccaa tagttgcatc ataagagagg atctctaaaa agaaaggtat gccttctgct
    12361 tcgcattctg aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt
    12421 tcatcaacgt catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt
    12481 ttcaccgacc aaatattcaa taaatcaggt aatcttcccg gaattttcgt atcatagccg
    12541 gttttttcat aagctagcag caagccacat tctttctctc gaagcgctgc tgcaggcagg
    12601 ccgtattctg gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc
    12661 tgtttaaatt ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc
    12721 aaagcaccac gctggtcgat tgctaacgcg ctaataattc cagcttcatc cgtcaatcgc
    12781 ttcaaacgtt cctgcttttc tatactcatc ttcttcatag atcttcacct atttctttag
    12841 ttaatattgt ggctattttt gtttttgatt ttgcttttct caactgttct gtaacctctt
    12901 ttcgcatcaa tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg
    12961 aatctggaat aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt
    13021 caattccttt gttcagtgtg acgataatca tactaggttc gttgattgtt tgagacttcg
    13081 catgaggaat agcaaaacct gacattattc ctgtagtacc ttctttttct ctttctagaa
    13141 gtttttgata tacatctttt tcgtcatgag caattcctaa gcagaatgtt tgctttgcta
    13201 aaaacttaaa tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat
    13261 gaatgattgt catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc
    13321 tttactatca tccatcttct tgtctttatc agttactctt ttcttttgga ttaatcctag
    13381 tatcactcca ccaacgatcg aaccaataag aatcgctgta acccattgga tttttcctgt
    13441 tactacaggt aatactaaaa aaccgccatg tggtgctgga acttggacgc caaacaaata
    13501 agtcaagaca gcagcaattg atgagcctaa catcatcgtg ggtaacactc ggatcgggtc
    13561 tttcgcagca aacggaatag ctccttccgt aatatgagtt gatcctaaaa taaaattaac
    13621 caaacctgca ttacgatcat tggtatcaaa atatttacca aacaataaag tagcaaaacc
    13681 agtaatcaac ggtggcgcaa tacaagctgc tgacacacca gccataaaag tcgtgtttcc
    13741 ttgtgccaaa agagctgttc ctgttacata tgccgcctta ttaaccggtc ctcccatatc
    13801 aaacgcacac atgcagccaa caatcacgcc aagaacaagt ggattcgaat gttcaaatcc
    13861 agctaaaaag ctcatcattc cttcatttat agccttcatt ggacctgcca gcaaagacat
    13921 cacgatgcca ataaatgcta cgccaataac tggatataag aagattgcct tcaagccatc
    13981 tagttgttta ggtaaaattg tcagtagctt ttgcaaaaat aagataaaat aacctgctaa
    14041 gaacccagct aaaatacctc ctaaaaatcc agtaccgcca ttcatggcta cgattccacc
    14101 aacaaatcca acgattaacc ctggacgttt cgcgatccct tctgcaatat aagctgctaa
    14161 aactggaacc atcattccca ttgatgcatc gccaactgct tttaccattg ccgctgtagc
    14221 attgtattgt gcatgatctg gatcaaaaga atagattccc caaacggcaa atgaaatagc
    14281 aatcaatact ccgccagcta ccacgaaagg caacatatga gagacaccgt tcatcaaatt
    14341 tttatagatg ctacgaccaa aattagcacc actcatcgct tctggttcta aagtatcagc
    14401 agcttcatta tctgctaaga cagtaccttt tcctgccaat gcttcgtcaa tcagccgttg
    14461 tgcatccttg attcctgtac tgacagaaac atcaatgact cgttttcccg caaatctttc
    14521 tgaatggaca tctttgtctg cggcaataat gacagcatct gcctgtttga tttcttcagc
    14581 cgttaattca ttttcgatcc caatttgtcc atgggtctct actttgatcg tgatgccttt
    14641 tttcctagct gcttgttcta atgcctcttg cgccatgtag gtatgcgcaa ttcctgtcgg
    14701 acaaccggtt gctgcaatta gttgatattt tcccatcttt cgaacctctc ttccctgatt
    14761 ttgatttgtt tacttaattc ctccacatct aaaaaatctg ttaatccttt gcgaaaagcg
    14821 gttgagctgc ctgctgctat gcttttacgt aacgtttcat caagcggtcg tcgattcatg
    14881 tatcctgcta aaaaagcgcc taacatggta tcacctgcac atgctgtatt gacaactttt
    14941 ccttttggcg agtttcctcg aaacaccctg tctttcgtaa aaagaattgc tcctttctca
    15001 ccgagggata acaaaacatt ttctgcacct aactctacta gtcgttgtcc ataaacaaag
    15061 taatcttcat ctgtaaccat ttttcgtccg aaccaagaag aaagttcttc ctcgttcggt
    15121 ttcagcaaaa atggtcgata gggtaaacaa tccatggctt cttgatcact actatcaata
    15181 atcaaatgaa tccccttttc ctgacaaatc cgactgattt ctattaaaac ctttggagac
    15241 agccctcttg gtaaactccc agaaacacaa agataatctt ctgcttgtaa tgctcttatt
    15301 tgatttaaaa aattatggac agctgtctgc ggtatttcag gtccttgatt cactaatttg
    15361 tattcttctc ccgtttgatt gacttgtgta aatacattga tacgcgtcat accaggcact
    15421 tcaataaact ctgtttggat ttgtttctgc tgtaaatagt cttctatata ctttcctgtg
    15481 aacccagcag aaaaacctaa tgccgtactt gggaaatcta gcatctttaa tactagtgac
    15541 acattcactc cttttccgtt tgcctgaatg tcatcctctt ttgtgcggtt taccataaaa
    15601 ggatgcatct cctctgtttc aataaataga tcaattgcca aattcatcgt gcatgtgtag
    15661 atagacataa ccaatgacct ccttgactct attatgaaat acgcgaaaga gaaaatgttt
    15721 tcttaatcgt tccaacacaa agaaaacctt tacatttata aactcgtcgt gctatttttt
    15781 aactaacttt tggtgaaaga aggaaagaat atggatcaca aattaagtga aacagaacag
    15841 tacctctgga actttatcga acaccatatc ctagagatcc ctaactactc catcgtgaaa
    15901 ctaagtgaac aagcaaatgt ctcaacagcc accattgtgc ggacaatgaa aaagaaaggc
    15961 tatgaagggt ttacttcgtt taagcatcat ctaaaagaag gagaaaacaa gaacatcaat
    16021 ttttctttct tagataaagt agacaaaggt atccgccgag ccattctaaa aaatgaacaa
    16081 gaagtggtac gtacgatcaa tgtgttggaa atcggaaata ttgaggatgc gatacaaaga
    16141 atcaaatttg ctgaccgggt ttttgtcttt gcccgaggat tttcagaaat gattggccaa
    16201 gaaatgctgg taaaacttca attaacggga aaaaattgtc aaatgcatac tgatccagaa
    16261 attatcaaaa gcatcagtca gaaactgact aagaaagaca gcgttatttt tgtttctttg
    16321 aacggcgaga caaaagaact cgtcaccgcc gcaaagaatt gctatgatgc agagattggt
    16381 tcgattctag ttacagccaa tcattcctct acactgaaag actattgcga gatcaatctc
    16441 gtaggtttca aatcagaagg ttcttatttc cctgattatg aagtacggtc acgcttgcct
    16501 ctccagatta tcgcgagaat tctgcttgac gcctatgtat tgcgtatggg ggagaattga
    16561 gaagcagttt attatggttg gttacagttt aaaacatcac attttttatt ctttatattg
    16621 tatagactca cgtaaacttt ttatgtataa agttattcac aatctataaa gttactttaa
    16681 gtaacaaaaa ataattgaaa atacttaaaa tcaaaaaata tctttttaat caataaaaaa
    16741 attgacagtt ttattaataa taagctattc tgttatagaa gaaaaaattg tttgttatta
    16801 ttagcaacaa aaaaaggagt gcatcatgaa aaagttatct caaaaacgtt tagctcaaat
    16861 cattattgat tctagaaaat ctctgaaaat gacacaacaa caacttgcag tagctactgg
    16921 tatcaaccgt gccttaatta gtcgattaga atctctcgat tttatcccgt caatacaaca
    16981 attagaatca ttagcagaag ttctaaattt tgaaccaaca gatctattta taaatgaatc
    17041 aaataaatca aacagaacaa aacatcagtc gaagaatatt gctgtagccg gtactggtta
    17101 cgtaggtctt tccattgcta ctcttcttgc ccagcacaat caggtaacag cagtagacat
    17161 tcttcctgaa aaagtaaaac aaattaacaa taagaaatct ccaatacaag acgattacat
    17221 tgaaaaatat ctagctgaaa aaaatcttaa tttaattgca acgactgatg gtgcagccgc
    17281 ctatagagaa gccgattttg ttgtcattgc tgctccaaca aattatgata gtaaacaaaa
    17341 ttattttgat acttctgctg tagagtcagt aatcaaattg gtgttagaag tcaatccaaa
    17401 ggcaataatg gtcatcaagt cgacggtacc cgtaggctat accgaaagta ttcgtaaaaa
    17461 atacaatact aaaaatattc tattcagccc agaatttctc agagaatcta aggcattata
    17521 tgacaatcta tatccttcgc gaattattgt cggcacggac caaactgaca aaactttacg
    17581 agaagcctct cacacttttg cagatttact ccaagaagga gcaatcaaaa aagatatcga
    17641 aactcttttc atgggattca cagaagctga agcagttaaa ttattcgcta atacttacct
    17701 tgcacttcga gtatcttact tcaatgagct ggatacttat gcagaaatga aaggactaaa
    17761 tacacaagaa atcattcacg gggtttgctt agatccaaga attggcacac attataataa
    17821 tccatctttt ggatatggag gctattgttt accgaaagat acaaaacaac ttctcactaa
    17881 ctataacgat gttcctcaga atatgataag tgcaattgtc gatagtaatc gtacaagaaa
    17941 agactttata gcagatcgag tgttagaact tgctggcacg tatgaggcta acagttcgtg
    18001 gaatgcagaa aaagaaaaag aggtagtcat aggtgtatac cgtcttacaa tgaagagtaa
    18061 ttcagacaac ttccgtcagt catctattca aggagttatg aagcgaatta aagcaaaggg
    18121 ggcaactatt gtaatttatg aaccaacact tgaaaataac actacatttt ttggttcaaa
    18181 agtaataaat aatttagatg attttaaaaa tatcagtcac agtattattg ctaatcgtta
    18241 cgatagtaat cttgatgatg taaaagaaaa agtatatacc agagatttat ttcaacgaga
    18301 ttaaaaaata acacctcaga tttgtagtgt ctgaggtgtt tctataaact tttataagta
    18361 aaaaaataca attatacttc ataaaaagac ttataccact gcgcaaattt acgaagcccg
    18421 tcacgcaaac ttgtacttgg tttaaattca aaatctcgtt ctaacgcact agtatctgca
    18481 taagtaactg gcacatctcc tggttgcatt ggaactagtt cggtatgaga ttcaaagtcg
    18541 taatcttctg gtagcacccc tgctgcaatt agctcttgtt gtagaatatc tacaaaatct
    18601 agtaggtttt ccggcgtatt gttaccaata ttataaatat gatatggtgg gattggtagc
    18661 ccatcttccc catcaatttt ctctggagcg cactgcataa ccctctttac tccttcaaca
    18721 atatcatcta tataggtaaa gtcacgcttg caattcccat aattgaatat ttggatatta
    18781 tcaccagcac gaagtttatc agtaaaacca aaataagcca tatctggacg cccagcagga
    18841 ccatatactg taaagaaacg taaccctgta gacggaatat tgtaaagttt agaatatgca
    18901 tgtgccattg attcattact tttcttagtt gctgcataca acgatacttg attgtctact
    18961 ttatcctctg tagaataagg aattttctta ttagtaccat aaacggaaga cgatgaggca
    19021 tacactaaat gttccacacc agattctcca ttatcatatg aatgacgaca agcttcaaga
    19081 atattataga atcctattat gttagattcg atatacatat ctggattagt aattgaataa
    19141 cggactcctg cctgagctgc taaattcacc acgatacttg gtttataatt atcaaagatg
    19201 aaatcaattg ttgctttatc agcaatagaa cctttgataa aattccaagt agatcctgga
    19261 tggttctttg cctccgtttc tatctctgat aatctatagt tcttaataga gacatcatag
    19321 taatcattca tattgtcaat gccaatgatt tttattgatg actgagtacg taataactca
    19381 agaaccaaat ttgatccaat aaaaccggct gcgccagtta ttaatattgt tctatttgat
    19441 aaggacgtgt ttaattccag cattttttag cactcacttt ctttttttct tatgaataca
    19501 tatttgttat atattaaaaa atcttattta gacttatcta ttgtcacttt tatcattcta
    19561 atctttgcac gtagtagaat aattatacag ataggaaatt gctaagcaac ccacttcttt
    19621 ctattatcta ttaacttatt ctaaa
//
LOCUS       DAZKNV010000050        18504 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000050 DAZKNV010000000
VERSION     DAZKNV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.050"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            99..746
                     /locus_tag="ACG8M1_002026"
     CDS             99..746
                     /locus_tag="ACG8M1_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFQ0422706.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    875..1091
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1139..3784
                     /locus_tag="ACG8M1_002027"
     CDS             1139..3784
                     /locus_tag="ACG8M1_002027"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFQ0422707.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="ACG8M1_002028"
     CDS             4094..5407
                     /locus_tag="ACG8M1_002028"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFQ0422708.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="ACG8M1_002029"
     CDS             5397..6050
                     /locus_tag="ACG8M1_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0422709.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /gene="radC"
                     /locus_tag="ACG8M1_002030"
     CDS             6105..6797
                     /gene="radC"
                     /locus_tag="ACG8M1_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFQ0422710.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="ACG8M1_002031"
     CDS             6947..7147
                     /locus_tag="ACG8M1_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0422711.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7401..9080)
                     /locus_tag="ACG8M1_002032"
     CDS             complement(7401..9080)
                     /locus_tag="ACG8M1_002032"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFQ0422712.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9082..9294)
                     /locus_tag="ACG8M1_002033"
     CDS             complement(9082..9294)
                     /locus_tag="ACG8M1_002033"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFQ0422713.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9687..11417
                     /gene="efrA"
                     /locus_tag="ACG8M1_002034"
     CDS             9687..11417
                     /gene="efrA"
                     /locus_tag="ACG8M1_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFQ0422714.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11414..13174
                     /gene="efrB"
                     /locus_tag="ACG8M1_002035"
     CDS             11414..13174
                     /gene="efrB"
                     /locus_tag="ACG8M1_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFQ0422715.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13269..13466
                     /locus_tag="ACG8M1_002036"
     CDS             13269..13466
                     /locus_tag="ACG8M1_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422716.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13619..14104
                     /locus_tag="ACG8M1_002037"
     CDS             13619..14104
                     /locus_tag="ACG8M1_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFQ0422717.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="ACG8M1_002038"
     CDS             complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="ACG8M1_002038"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFQ0422718.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14981..15502
                     /locus_tag="ACG8M1_002039"
     CDS             14981..15502
                     /locus_tag="ACG8M1_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422719.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            15599..16336
                     /locus_tag="ACG8M1_002040"
     CDS             15599..16336
                     /locus_tag="ACG8M1_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFQ0422720.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16340..17257
                     /gene="miaA"
                     /locus_tag="ACG8M1_002041"
     CDS             16340..17257
                     /gene="miaA"
                     /locus_tag="ACG8M1_002041"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFQ0422721.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17259..18488
                     /gene="hflX"
                     /locus_tag="ACG8M1_002042"
     CDS             17259..18488
                     /gene="hflX"
                     /locus_tag="ACG8M1_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFQ0422722.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5984 a         3200 c         4022 g         5298 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt
     7261 atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga
     7321 acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg
     7381 ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt
     7441 ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc
     7501 aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt
     7561 cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga
     7621 atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca
     7681 agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc
     7741 ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg
     7801 ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct
     7861 acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata
     7921 aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg
     7981 gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa
     8041 ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact
     8101 gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg
     8161 gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga
     8221 ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga
     8281 ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc
     8341 acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg
     8401 atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat
     8461 ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct
     8521 tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat
     8581 ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca
     8641 tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc
     8701 gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg
     8761 tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc
     8821 aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact
     8881 ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa
     8941 tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc
     9001 ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta
     9061 tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc
     9121 gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc
     9181 ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc
     9241 ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt
     9301 gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa
     9361 cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa
     9421 agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat
     9481 aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc
     9541 aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt
     9601 atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta
     9661 acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata
     9721 agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac
     9781 ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg
     9841 tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct
     9901 tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt
     9961 tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat
    10021 tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac
    10081 gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa
    10141 gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag
    10201 cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca
    10261 acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa
    10321 agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct
    10381 tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg
    10441 tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt
    10501 tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg
    10561 tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg
    10621 ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata
    10681 tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa
    10741 atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg
    10801 gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct
    10861 tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt
    10921 ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga
    10981 aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat
    11041 tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt
    11101 caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct
    11161 atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc
    11221 gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga
    11281 tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc
    11341 atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa
    11401 aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag
    11461 accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa
    11521 cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa
    11581 tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg
    11641 aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag
    11701 tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata
    11761 tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt
    11821 cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt
    11881 ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat
    11941 tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag
    12001 catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag
    12061 tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca
    12121 cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt
    12181 tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat
    12241 tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag
    12301 tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac
    12361 gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc
    12421 actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc
    12481 gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt
    12541 ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga
    12601 cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga
    12661 tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc
    12721 agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa
    12781 aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa
    12841 ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt
    12901 ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt
    12961 agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat
    13021 cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca
    13081 gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact
    13141 gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa
    13201 acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg
    13261 acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc
    13321 gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt
    13381 ttcaaatcga acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa
    13441 tagaagaaaa tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa
    13501 atagacatct ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct
    13561 atgatacctt tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat
    13621 ggaacggttt atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt
    13681 gacgatctgg tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag
    13741 aacgaatatc caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc
    13801 ggagaatgtg acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc
    13861 gctgatcggg atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat
    13921 tggtgctgga tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg
    13981 tcgcccagct aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa
    14041 catccagcat tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag
    14101 ataggcagta gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt
    14161 tatttggttt agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa
    14221 gaactgtttt ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata
    14281 tagttgtcac gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct
    14341 aaaattttgt ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca
    14401 gttgcttgcc cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa
    14461 gcaaatcgtt taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata
    14521 cccataacaa ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata
    14581 cctgctgtaa ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct
    14641 tgagcgtcta agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg
    14701 ccgcttaaca tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca
    14761 cctcgtgaag attgttcaat gactgtagga attaaattca taatagagtt cctccttgat
    14821 ttcgtttaga aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt
    14881 ttggtcaaaa aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg
    14941 gtatgataag cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg
    15001 ccttatcgga gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg
    15061 tcacttggaa aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga
    15121 gacgctgaat caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat
    15181 ggaagaatat gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc
    15241 gtatctccaa tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga
    15301 gctatttaag aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat
    15361 tggtggatat gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac
    15421 tgaaatgatc aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt
    15481 cttctcgaaa gatgatgttt gaagctgata ttttgaagca ttgccgttgc acatgagagc
    15541 gtggtaatgc tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat
    15601 gttacaaatc tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc
    15661 atttgcagaa gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa
    15721 agatggttat ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg
    15781 gctgattcga gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag
    15841 caaagaattt ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca
    15901 aaaaaattac cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg
    15961 tatcgaagaa aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata
    16021 ttgcagcttt catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct
    16081 ggacttattg atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat
    16141 agaaggagta catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt
    16201 tccaaaagca attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga
    16261 actcaaaata gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc
    16321 aacgaaaagt aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg
    16381 taaaacagcg ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga
    16441 ttcattgcaa atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat
    16501 gaataatgtt ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc
    16561 tgattttcag cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc
    16621 tatcatagct ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg
    16681 agcgacagaa gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat
    16741 tggttcccaa gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat
    16801 ccactggaac aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca
    16861 tagtatcacg gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt
    16921 agatacgaag cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc
    16981 agaaggttta gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca
    17041 aggtattgga tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc
    17101 aacagaacaa gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg
    17161 taaccgtttg gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat
    17221 tgagcaaaca atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg
    17281 taggggtaga aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc
    17341 agctgacgaa taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag
    17401 tggatcggca aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg
    17461 cgcatgaagc ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga
    17521 ttaccgatgc tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg
    17581 cgatgcgtgc tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc
    17641 tgctgcctcg tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa
    17701 caagagggcc aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt
    17761 ttgctgttaa gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa
    17821 gaaaaaatag cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa
    17881 ctatcttgaa tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt
    17941 tagatccatt gactaagaga tggcgttttg ctgaaggatt tgagattgct gtaacggata
    18001 ccgtcgggtt catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag
    18061 aagaaagtca aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta
    18121 ttttacagga gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga
    18181 tactgactgt ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat
    18241 tcccaaatgt attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa
    18301 tcaaacgtca gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag
    18361 gacagaaatt aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag
    18421 aaacaaacga atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa
    18481 accaataaaa ttttattttt ttaa
//
LOCUS       DAZKNV010000051        18107 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000051 DAZKNV010000000
VERSION     DAZKNV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.051"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(164..388)
                     /locus_tag="ACG8M1_002043"
     CDS             complement(164..388)
                     /locus_tag="ACG8M1_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFQ0422723.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="ACG8M1_002044"
     CDS             complement(586..2166)
                     /locus_tag="ACG8M1_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFQ0422724.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="ACG8M1_002045"
     CDS             complement(2567..3943)
                     /locus_tag="ACG8M1_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFQ0422725.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5159)
                     /locus_tag="ACG8M1_002046"
     CDS             complement(4071..5159)
                     /locus_tag="ACG8M1_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0422726.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="ACG8M1_002047"
     CDS             5331..5765
                     /locus_tag="ACG8M1_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422727.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="ACG8M1_002048"
     CDS             complement(5843..6376)
                     /locus_tag="ACG8M1_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFQ0422728.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACG8M1_002049"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACG8M1_002049"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFQ0422729.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACG8M1_002050"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACG8M1_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFQ0422730.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="ACG8M1_002051"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="ACG8M1_002051"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFQ0422731.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="ACG8M1_002052"
     CDS             complement(10101..10679)
                     /locus_tag="ACG8M1_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFQ0422732.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="ACG8M1_002053"
     CDS             11001..11471
                     /locus_tag="ACG8M1_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFQ0422733.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="ACG8M1_002054"
     CDS             complement(11579..12805)
                     /locus_tag="ACG8M1_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0422734.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13559..13759)
                     /locus_tag="ACG8M1_002055"
     CDS             complement(13559..13759)
                     /locus_tag="ACG8M1_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0422735.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13893..14501)
                     /locus_tag="ACG8M1_002056"
     CDS             complement(13893..14501)
                     /locus_tag="ACG8M1_002056"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFQ0422736.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14586..15056)
                     /locus_tag="ACG8M1_002057"
     CDS             complement(14586..15056)
                     /locus_tag="ACG8M1_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFQ0422737.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(15104..16018)
                     /locus_tag="ACG8M1_002058"
     CDS             complement(15104..16018)
                     /locus_tag="ACG8M1_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0422738.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            16164..16967
                     /locus_tag="ACG8M1_002059"
     CDS             16164..16967
                     /locus_tag="ACG8M1_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFQ0422739.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            17145..18092
                     /locus_tag="ACG8M1_002060"
     CDS             17145..18092
                     /locus_tag="ACG8M1_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFQ0422740.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         5438 a         3631 c         2964 g         6074 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt
    13501 cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt
    13561 ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta
    13621 cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa
    13681 atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt
    13741 taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc
    13801 aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat
    13861 tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt
    13921 acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg gacattttta
    13981 tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc
    14041 atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca
    14101 agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa
    14161 gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca
    14221 ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg
    14281 ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct
    14341 attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa
    14401 gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat
    14461 gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat
    14521 gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt
    14581 tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta
    14641 aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt
    14701 ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc
    14761 aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta
    14821 aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca
    14881 gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg
    14941 agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt
    15001 atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc
    15061 caacctacct tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt
    15121 tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat
    15181 gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct
    15241 cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat
    15301 actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt
    15361 ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga
    15421 tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga
    15481 tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca
    15541 gtgtatcact taacaaatgc aaataactag attttatatt caaactttca tctgcttctt
    15601 gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca
    15661 tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa
    15721 acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct
    15781 ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag
    15841 aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac
    15901 tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta
    15961 ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt
    16021 tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt
    16081 cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg
    16141 acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac
    16201 gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt
    16261 tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca
    16321 acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg
    16381 ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca
    16441 catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt
    16501 ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga
    16561 cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa
    16621 acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa
    16681 aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc
    16741 tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc
    16801 ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct
    16861 tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta
    16921 tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa
    16981 ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc
    17041 cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc
    17101 ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca
    17161 tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg
    17221 gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg
    17281 gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa tgggtccaat
    17341 ctatctcagc tggtgttgat cagctacccc ttgagacttt ttcaaagaaa catattttac
    17401 tttcaaatgg tagtggcatc cacagtgaat cgattacgga gcatgtctta ggaatcatcc
    17461 ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg aaatggttag
    17521 gttcatcggt ccattaccaa tctatccaag ggaaaaaaat actaatcatt ggaactggcc
    17581 atattggaaa aatgattgca aaaaaatgca aagcattaga catgaactgc tatggaatca
    17641 atacatccgg tcatccagca gaaggaatgg aaaagacttt ttctttaaat caactaaagg
    17701 aagttcttcc tgaagtagat ttcgtagtca atatcttacc tctaacggag gaaacaactg
    17761 ggctctttga tcagcatatg tttgaacact ttgatccaaa atctgtattc atcaatgttg
    17821 gccgtggtgc ttctgttaag acacaagatc tggtgcaggc tttaaataac cagcaacttt
    17881 cctttgcagc attagacgtt tttgaggaag agcctcttcc acaagatcat cctctttgga
    17941 aaatggacaa tgtactgatt acttcccaca ttgcaggttt gacacctgat tttcaaaaga
    18001 aattaatggc tattttttta accaatctga aaagctactt tgccacccat gagcttcaaa
    18061 ccaatcaagt aaaattgtct gcaggatatt aatagctgaa aacaata
//
LOCUS       DAZKNV010000052        17799 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000052 DAZKNV010000000
VERSION     DAZKNV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.052"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            163..393
                     /locus_tag="ACG8M1_002061"
     CDS             163..393
                     /locus_tag="ACG8M1_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFQ0422741.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            490..1791
                     /gene="murA"
                     /locus_tag="ACG8M1_002062"
     CDS             490..1791
                     /gene="murA"
                     /locus_tag="ACG8M1_002062"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFQ0422742.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1804..1980
                     /locus_tag="ACG8M1_002063"
     CDS             1804..1980
                     /locus_tag="ACG8M1_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFQ0422743.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2115..2411
                     /gene="yidD"
                     /locus_tag="ACG8M1_002064"
     CDS             2115..2411
                     /gene="yidD"
                     /locus_tag="ACG8M1_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFQ0422744.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2596..3063
                     /locus_tag="ACG8M1_002065"
     CDS             2596..3063
                     /locus_tag="ACG8M1_002065"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422745.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3148..4032
                     /locus_tag="ACG8M1_002066"
     CDS             3148..4032
                     /locus_tag="ACG8M1_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0422746.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4146..4382
                     /locus_tag="ACG8M1_002067"
     CDS             4146..4382
                     /locus_tag="ACG8M1_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFQ0422747.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4470..4550
                     /locus_tag="ACG8M1_002068"
     tRNA            4470..4550
                     /locus_tag="ACG8M1_002068"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4504..4506,aa:Tyr,seq:gta)
     gene            4557..4628
                     /locus_tag="ACG8M1_002069"
     tRNA            4557..4628
                     /locus_tag="ACG8M1_002069"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4589..4591,aa:Gln,seq:ttg)
     gene            4753..4923
                     /locus_tag="ACG8M1_002070"
     CDS             4753..4923
                     /locus_tag="ACG8M1_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422748.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5143..5850
                     /locus_tag="ACG8M1_002071"
     CDS             5143..5850
                     /locus_tag="ACG8M1_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0422749.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5909..6553)
                     /locus_tag="ACG8M1_002072"
     CDS             complement(5909..6553)
                     /locus_tag="ACG8M1_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFQ0422750.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6679..6966
                     /locus_tag="ACG8M1_002073"
     CDS             6679..6966
                     /locus_tag="ACG8M1_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422751.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7074..7394
                     /locus_tag="ACG8M1_002074"
     CDS             7074..7394
                     /locus_tag="ACG8M1_002074"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0422752.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7475..8789
                     /locus_tag="ACG8M1_002075"
                     /pseudo
     CDS             7475..8789
                     /locus_tag="ACG8M1_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            8786..9505
                     /locus_tag="ACG8M1_002076"
     CDS             8786..9505
                     /locus_tag="ACG8M1_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFQ0422753.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9633..10184
                     /gene="raiA"
                     /locus_tag="ACG8M1_002077"
     CDS             9633..10184
                     /gene="raiA"
                     /locus_tag="ACG8M1_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFQ0422754.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10406..12940
                     /gene="secA"
                     /locus_tag="ACG8M1_002078"
     CDS             10406..12940
                     /gene="secA"
                     /locus_tag="ACG8M1_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFQ0422755.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13066..14167
                     /gene="prfB"
                     /locus_tag="ACG8M1_002079"
     CDS             join(13066..13137,13139..14167)
                     /gene="prfB"
                     /locus_tag="ACG8M1_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFQ0422756.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14272..14958
                     /gene="ftsE"
                     /locus_tag="ACG8M1_002080"
     CDS             14272..14958
                     /gene="ftsE"
                     /locus_tag="ACG8M1_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFQ0422757.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14951..15835
                     /gene="ftsX"
                     /locus_tag="ACG8M1_002081"
     CDS             14951..15835
                     /gene="ftsX"
                     /locus_tag="ACG8M1_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFQ0422758.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            15987..17435
                     /gene="cls"
                     /locus_tag="ACG8M1_002082"
     CDS             15987..17435
                     /gene="cls"
                     /locus_tag="ACG8M1_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFQ0422759.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT         5960 a         2991 c         3845 g         5003 t
ORIGIN      
        1 cttttgtctc agtccctttt tttgcatatt tttagcattt atttcctaaa aaatgtaagg
       61 ggattcctat atttttaagt atacttgttt ttccttttat acattttatg gtattatcat
      121 tttattagtt attataaaac aatcgttaga aaggacgtca ttatgcaagt atacggaatt
      181 gatgcggtgc ttcgaatcgt gagtcatttg gcgtttatct acttagcctt ctggtcttta
      241 cgttcgttac gcattgaaac ttttttcaga ccaatgcata atacgcaaat tagaatggca
      301 atcgtacttt tttcaatttt tttagggtac actgcaagta attttttctt agaagttatc
      361 gctttatgcc gaaatctttt cgttagcctg taaattttaa aaaaaggtac tattttaaaa
      421 gcaaggatgt tataatagaa aagattttga gtaagtgtat gctcattgga attttttgga
      481 gggaacaaca tggaagagat catcgtaaga ggtggcaatc aattaaatgg aacagtaaga
      541 attgaaggag ctaaaaatgc tgttttgcct attttagctg ctagtttgtt agcagaagaa
      601 ggtattacga cattagacaa cgttccgatt ctttctgatg tcttcactat gaatcaagtg
      661 attcgtcact taaacgtaga tgtagatttt gatgaacaaa agaatcaagt aacaatcgac
      721 gcttcaagac aattagaaat cgaagcgcct tatgagtatg ttagtcaaat gcgtgcttca
      781 atcgttgtga tgggtccgct acttgccaga aatggacatg caaaagtagc tatgcctggt
      841 ggatgtgcga ttggtaaacg accaatcgat ttgcatttaa aaggatttca agctttagga
      901 gcaaaaatta ttcaaaaaaa cggctatatc gaagcaattg cggatgaatt gatcggtaac
      961 acgatttatt tagatttccc tagtgtaggt gctactcaaa atatcatgat ggctgccgta
     1021 aaagcaaaag gaacaaccat cattgaaaac gtagctcgcg aaccagaaat cgttgattta
     1081 gcaaacattt tgaataaaat gggcgctcaa gtctatggag ctggtactga aacaatgcgt
     1141 attgaaggcg tggatcattt acatgcagtc aaccactcaa tcgtacaaga tcgtatcgaa
     1201 gcaggtacct ttatggttgc tgctgcaatg acacaaggca atgtgctgat tgcagatgct
     1261 atctctgaac ataaccgccc attgatttct aaattgatcg aaatgggtgc agaaatcatt
     1321 gaagaagaag gcggagtccg tgtcatcgga ccaaaacata tcttacctac agatgtaaaa
     1381 acgatgcctc atcctggttt ccctacagat atgcaagctc aaatgacagc tatccaatta
     1441 gttgcagaag gtacaagtgt agtgactgaa acagtgtttg aaaatcgttt ccaacattta
     1501 gaagagatgc gccgtatgaa cgctcatgtc aaaatcgacg gaaatgtagc aatcatggat
     1561 ggaaaccatg aattgcaagg tgcagaagta tatgcaacag acttgcgggc agcagcagca
     1621 ttagttttag ctggcttgaa agcaaatgga atcacacgtg tgcgtaactt gaattatcta
     1681 gaccgtggat attataattt ccatatcaaa ctacagcaat taggtgcaga cgttgaacgt
     1741 gtagacatgg atcaaacttc tgctgaaaaa acagcacaaa cgattgctta aggaagtggc
     1801 tgaatgagta accaacgata tatcttatta actttgataa agattttaat ggtgatctta
     1861 ttgcttatcc ttctttttgt ggccggaacg atgatcggat atggtgtcat cggtggcggc
     1921 aatccattta aagtatttca gccaagtttg tggattcata ttcgagactt ttttcattga
     1981 taaataagaa tcacagtggt tctagtcgat atgaagtgag ccatgaagca gaacatgata
     2041 aaagaaaaca gaagggaacg ttgacgttag tcgcgatccc tttttttagt aaaagaaaag
     2101 aaggaatcta attgatgaag aagatattga tttatttagt tagaggatat cagcgcttta
     2161 tttcgcctgc atttccacct agctgccgtt attacccaac ctgttccaat tatatgataa
     2221 aagcaattca aacccatggc gcgctaaaag ggacggtaat ggggactgca cggatcttac
     2281 gctgtcatcc ttttgtcaaa ggcggtatcg attatgtacc attgacattc cgattaacgc
     2341 gaaataagaa agataaaaaa gaaccagatt ataaaaaggt tgtgaaaaat acgggtagca
     2401 ctgagcgata aagaaacaat ttggaaaata gcttcttata ttttgcaaaa ttgtgagtta
     2461 ttgccgaagt gttggatttt gaacaccgtc aaaaaaaagg ttgtgaaaaa tacggctagc
     2521 actgagcgat aaagaaaaag aggaaattta ttgtcaaagt aacaactccg caactactta
     2581 tatgggggac aaaaaatgat cgaagaacta aacaagaaag atttaccatg gtccttgtta
     2641 ttagatgcag atcctgataa agaaaaagtt caagtatatg tttccagagg gagtggctgg
     2701 atatggaaag aaaaagaaaa aacaataggt gtactgatct atgtggcaag ggaaaaagaa
     2761 tacgaaatcg tcaatgtagc agtaacccca acgtatcaag gaaaggggat tggcggaaaa
     2821 ttacttgaga cagcttttca gaagctttca caactcgctt ccagtcaaac tcagatcatc
     2881 atacgaaccg gcagtactag cagtgcggcg ttacatctct atcaaaaaat gggctatgtg
     2941 gagattggtc gagtcaaaga ctattttatc catcattact ctgagcccat ttttgaaaat
     3001 ggagatcaat taagggatca agtgatttta gcaattcact tacctaaaaa tagctttaac
     3061 taataaaatt tcaattcaag aaaatgcttt caaatgctaa atagatacat tacaatagct
     3121 ttagcaaaca aaaaggagaa tatttttatg ggaatattag tttttgattt tggtggatcg
     3181 gctgtcaaat atggttgttg ggatggcaaa gagattaaag gtaagggaca atttgcaacg
     3241 cctgaatctt gggaagaaat gaaagcgcaa ttatttcaag tttataaaaa aatactcgtt
     3301 tcttttgaag tcgaaggaat tggaatcagc tctcctggag tagtgaataa tgagaaacag
     3361 gtgattgagg gaatcagtgc gattccttat attcatggat ttaatatttt ccgagatttg
     3421 gaaactctgt ttcaacttcc agtaacgatt gaaaatgacg ccaactgtgc cggaatggct
     3481 gaattttatg aaggtgctgc ccgcgattat caagatgttg cttttgttgt ggcaggaact
     3541 gggattggcg gggcgttgtt cacgaaagga caaatcaata aaggggcaca tctttacggt
     3601 ggagaatttg ggttgatgtt cttaaatggc gataagacat tcagtaaact tggtacagcg
     3661 gtacagatgg cttggcgtta ttgtgaacgc aaaggtctcg ataaaaatgc ttataccgga
     3721 aaagatgtct ttgaattagc agaaactgga gatgcaatag caaaagaaga agttgagagt
     3781 ttttatacgt atcttacaaa gggattattc agtattcaat tttcgtttga tccagaagtg
     3841 atcgtattag gcggcggggt ttctgcaaaa gaagggctca ttgatgagat caaaagccga
     3901 atgaagaagc tgacagaaca attcgatctg catgatttcg aaccgcagat tttattatgt
     3961 gaatacagaa acgatgctaa tcttgtaggt gcagcagcaa actatctcgc tgtacgtcaa
     4021 ggggagaatt aagagcttta gagaaggtgc agcttgcata aaagaagtga atgaaatgaa
     4081 taggagattt ttacctaagg aatgttttat ttgctgcagt atgataaaat atctgagagg
     4141 tgaaaatgat gtcaaaaaaa aataaagata ttgaagtgcg tatagaagaa gtgaaaaaag
     4201 atatcaaagg taagaattat gaagtcactc agttatttat agggaaaaaa atgattggtg
     4261 agatcttagc ctatggacca aaagaatatg aaattttctt tggtgaagaa gattttggaa
     4321 aagaaaaaag tcttgaaaat gcgatagaaa cagtgattcg acactggaat ctgcacgaat
     4381 aaaaaaatat caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa ttaggtatta
     4441 taactaagtc aggttgatac aaacctttcg gaggagtagc gaagtggcta aacgcgacgg
     4501 actgtaaatc cgttccttag ggttcagtgg ttcgaatcca ctctcctcca tttcattggg
     4561 gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt cgaatccagc
     4621 taccccagta taccacaatc gtaagctctc gttagttcga gagctctttt ttttgctttg
     4681 ctaccttgtt ccttgaagat tctgctgatt taagatagag ttaagttaac tacaagaatt
     4741 ggagggatcc acatgaaatg gaaagaaaaa gtagacgaag cagctgaaaa gttatatgat
     4801 ttggtcaaat cagaaaaata caatattgaa gtgaatattc cgaaaaaagg cggaaaagcg
     4861 gtccgggtaa aatcaaaacg cccaacgaat catacaaaaa aatggatggc taaaaaccgc
     4921 taataataac aaaagatcca taagtcggca ttttcatcga ttttagggtc ttttgttatt
     4981 ttctaggttg gacatatcta aaaaattgtt tctgacaata ggagtaggaa gaacgatgtg
     5041 tgtctaaatc ctctgttgat ggatagaaac ctttatcttt ttcagttgtg aatcaggtat
     5101 ataccagtta taatagaaga aacgaaagga cgggtgtacg ttatgtcgaa tcaattacct
     5161 gtatatatac agattcatga ccaattaaaa aatgaaatcg aacaaggtat atggaaagtc
     5221 ggagaccgtc ttccttcaga aagagaatta gcagtgaaat tcaatgtcag ccgtatgacg
     5281 ttgagacaag caattcaaaa cttggcagat gaaggaatct tagaaagaaa gatcggttcg
     5341 ggtacatatg ttgcacgaga aaaagtacaa gaaaaaatgt ctggtgcaac aagttttaca
     5401 gaaattatgg aatcacaaaa tcgagtaccg tctagtcgga caatctctta tttcttgact
     5461 tcgccaagct caagtgaaat ggaaaaacta aacttgagta aagatgacac gatcttgcga
     5521 atggaacgta ttcgtttcgc agatgatgtc cctatttgtt ttgaagttgc cagtgtgcca
     5581 caaaagctga tcgatggcta cagcaaagca gagattactg aatcgttgta tcgcacgcta
     5641 gaagaaaaag gcgggaaaaa gatcggtcca gcgaatcaaa cgattactgc tgtgttggct
     5701 tctgagaaaa ttgctgacta tttagaggta aaacgaggag atgcagttct tcgtttgcgc
     5761 cagatttctt attttgaaga cggtacgccg tttgagtatg tgcgtacgca atacgtagga
     5821 aatcgttttg agttttattt ggaaaaataa aaaacaggtg atccctgatt ccgtattaga
     5881 aataaaagag aatcagaatc acctgttttt atatatgatc agttaccagt tgctcgtgat
     5941 aagaaacagg accctcttca aattggactt gtccgttcag cagctcaatg atggattctt
     6001 taaagtggtc agcacttttt tcatctacag cacagatgac gctaacttga tcagtatatt
     6061 ggatttcttt tataaaaaaa tgttggagtt caagataatt ctgtaatttt cctagttgcg
     6121 gatacgtgat catcacagag atctcctgtt gcaaggtacc ttctacgatt ccaatgtcag
     6181 acaatgcttg agagaccgca tgagtgtatg ctcgtattaa tccgcctgtg ccgagtttcg
     6241 ttcctccaaa atatcgagtg actactgcag ctacattgat cagttgattt tttttgagga
     6301 cttccaacat cggtatgccc gccgttccac ttggttctcc atcatcgctg cttcgctgga
     6361 tttcattttt ttctccaatg atgaaggcgc tgcagttatg gttcgctttc caatgttctt
     6421 tttttatttc ttgaatgaaa ctttttgctt cgtcctctga ttctattcgt ctaagagaac
     6481 agataaagcg tgattttttg atctcgatct cactttgtcc attttctttt attgtacgat
     6541 agcgctcgat catcttgtca cctctttttt cattttcttt attcagtata aataaagttc
     6601 taggttgttt caacactgta acggttgcgc aattgctgta gtatgcgata ataaagacaa
     6661 aggcaggtgg atctggggat gcaggaacga atgaaaaagt acgatgcaat tacgcattat
     6721 ttgaagaaca atggcggctc tcaagtaacg ttgaccttta cccaatttga cgaactgctg
     6781 tttcccagta acggacttcc caaaacagca agggaaagta cagattggtg ggcaaatgat
     6841 tataaacacc ctgaaaaagg tgcctatggc tggataaatg caggctatga agtagttgtc
     6901 atcaatttgg acaaagaata tgtcgtgttc aataaattag tgaaatctag ttggctattt
     6961 gattaaataa accgcgttta gaaaacgttg acaaatttct ttctttttat ataatagagt
     7021 aacagacgcg aagaaaacgt ttgcgtagtt tgttttaaaa aggagagaaa agtatggcta
     7081 aaaaaacaat catgcttgta tgttcggctg gtatgagcac aagtttacta gtaacaaaaa
     7141 tgcaaaaagc tgctgaagca aaaggaatcg actctgatat tttcgctgtg tccgcttctg
     7201 acgcagataa caatcttgca aataaagacg tggatgtgtt gttattaggc ccacaagttc
     7261 gctttatgaa agctgatttt gagaaacgtc tggaaccaaa aggcattcct ttagatgtca
     7321 tcaatatggc tgattatggt atgatgaatg gcgaaaaagt gttagatcaa gcaatcacgc
     7381 tcataggtga ataaatagaa cagtataact atcgaacaag cgatccaaaa aatagatcgc
     7441 ttgttttttc gtatattttt ttagggcgaa taatatgaat catttttggg gtagaaggct
     7501 tctgacgaga gatattaaag caatagactg tgaggaggta aatttaccaa attatgagaa
     7561 gatcgcagca gtggaacgtt tgagcaactg gattctttgt catcgctgtg gaatgagaac
     7621 gtccgtcatt gatggacagc ttgcagatta cggttatttt tgtacacatt gtctatattt
     7681 agggcgatgc gacactcaac aagatttata tttgtttgat cagcctgaag caaaacctcg
     7741 agaagtcgtc ttttttttgg acaggacagc ttactgaaaa acaaacggaa atctcaaaga
     7801 gaatactttg ccattcagaa aaaagacatc atcttatttg ggctgtaaca ggtgcaggga
     7861 aaacagagat gctttatcct attttagtgg aaactttaaa agctggagga agagtagcga
     7921 tttgtacacc gcgagtcgat gtttgtaatg aattgttttt acgctatcgt tatgtttttc
     7981 cagaagaaaa aatcacgttg ctccatggga atacagcaac ggcttatacc tttacttctt
     8041 ttgttatctg tacgattcat cagctatacc gtttttatcg gtcctttgat ttaatagtga
     8101 tcgatgagat cgatgcgttt ccttataacg gggatgcagg attagctcat gctgtgcaaa
     8161 cagcgattaa accagacgga cgattcatct acttaagtgc cacacctgat aaaaagttac
     8221 taaaggagat caagcagacg tttgacatcc acaaacttgc tttacgcttt catcggcgtt
     8281 tgcttcctga acccgtcttg gttttcatga ataattggcg acaaaaatgc aagaacaaga
     8341 agaagataaa atctttggtg cggatcattc atcaattaat taaagaaaac catatccttt
     8401 tattttgtcc aagtatcacg atgatgcatc gtttgaaagc cacacttcaa gaggctcttc
     8461 cgagatatga gatcacagat gtttcttcaa gagacaatca gcgggcggaa aaagtccaga
     8521 aaatgcgaga agcaaaatat gacatactgt taaccacgat gatccttgaa cgtggagtca
     8581 catttgaaag aatatccgtt atcgttttag gagcggatca tccggttttt actaaatctt
     8641 ctttggtaca aatcgcagga agagccgatc gtaaagggcc ttatacgaac agtcaagtat
     8701 attttttcta tgaagaaaaa actgcagcta ttcgaaaagc ttgtcaggaa atcaaagaaa
     8761 tgaatgaaga agggaagaag atactgtgag gtgcagttgc tgcagtaaag atatcgtcca
     8821 aaatttaaca ttcagcgaga ttattggtgt ttcgaaatac agattacctc agacttgttc
     8881 agtttgtcgc gcacaatttc atttattgga aacaagaggc tgttctggct gtcaaaaacc
     8941 aatccatttc aatctagaga gtacgaaaaa gaaagtaaat tctatccccg tttactgcag
     9001 tgactgtcaa gaatggaaga agaaatatcc gacctatgat tttcagcacc gtgccttttt
     9061 tgtgtacgat gaaaatatga aggcctggct caatcaatac aagtttatgg gagatatccg
     9121 actagcaggc acctttgcat ataaatggac gcagataaaa aaagaatacc cgacatacat
     9181 ctattgtcca atacctttat ctgaaaaaag gcgaacagaa agaggattca atcaagtaag
     9241 cgagatgttg aaagcagcaa gaattccttt tcagatgcta ctcaaaagag agaagcatct
     9301 gctggctcaa gcaaaaaaca cgcgaaagga aagattggag atgcctcaac cttttgaact
     9361 tgcagtcacc ttttctaaga tacaaaataa aaaaatattg attattgatg atgtctatac
     9421 aacaggacag actcttttcc acgcagcaga ttgtttgcag atcgcacagc cgaaaatcat
     9481 ccgaactatt tctttggcga gatgaattag atgtggaaat ttgatagcga tttaatttgc
     9541 aaataaccta gagttcgata taatagaatt aagaagaggg aaagagtggt ccttctcctt
     9601 cttgattgtg gtagacgaaa ggggtaattt ttatgtttag atataatgta cgcggcgaaa
     9661 atatcgaagt aactgaagcg attcgcgact acgttgagaa aaaagtaggc aaactagaac
     9721 gctatttcag tgacgcaccc gatgcaacgg cgcatgtgaa cttaaaagtt tatacagaaa
     9781 aaacagcaaa agtggaagta acgatcccat taccttatct tgtattacgt gccgaagaaa
     9841 cttctccaga tttatacgca agtatcgatt tggttgttga caaattggaa cgccaaatcc
     9901 gcaaattcaa aacaaaaatt aatcgtaaat cccgtgaaac gggcatgaat actgcaaatg
     9961 ctgctgcttt attcaatgaa gaggacgaaa acgaaaatga ttctgaatta gatatcgtac
    10021 gtacgaaacg cctttcattg aaaccaatgg atagtgaaga agcagtcttg caaatgaaca
    10081 tgctgggaca taacttcttt atttttgaag atgcagaaac aaatggtaca agtatcgttt
    10141 accgccgtaa agatggaaaa tacggactga ttgaaacaga ctgatcagcc ttacttaaat
    10201 aacaacgaaa acttgcagca gctactgaca gctgccgcaa gtttttttga gtttcctcct
    10261 cttttagatg aaatatgaat aaattatgaa gttcttactt taatacgctt aagatatttc
    10321 aattatctat aactaatgat aaaatgaaaa gtaaagtcta catagtctgg ataatacaca
    10381 gaaggaaaag gagattacac aacgcatggc caatttgatt cgttcactta tcgaaaacga
    10441 taagaaagaa ctaaaacgtt tagatagcat tgcaaaaaaa gttgaagcat acgctgacca
    10501 aatggcagca ttaactgatg aacaattaca ggcaaaaact gctgaattca agggcagata
    10561 ccaaaaagga gaaacattag atcaattact tccggaagct tttgcagtcg tccgagaagc
    10621 agcaaaacgt gtattaggtt tatatccata ccacgtacaa ttgatgggtg gaatcgtgct
    10681 tcacgatgga aatatccctg aaatgcgtac tggtgaaggt aaaaccttga ccgcaacgat
    10741 gccagtatat ctaaatgctc tgactggcga aggggtacac gtagttaccg tcaatgaata
    10801 tttagcaacc cgtgactcga cggaaatggg cgaactttat aatttcttag gattaacagt
    10861 ggggttgaat atcaactcaa aatcttcgga tgaaaaacgc gaggcttata attgtgatat
    10921 cacttatagt acgaataatg aattaggatt tgactacttg agagacaata tggtcgttta
    10981 ccgccatcaa atggtacaac gtccgctgaa ttatgccatt gtcgatgaag ttgactcaat
    11041 cttgattgat gaagcgagaa cgccgctgat catttcaggg caagcagaaa aatccacagc
    11101 tttatataca agagcagaca acttcgtgaa acgtttgaaa gaagaagaag attataaaat
    11161 cgatgtacaa tcaaaaacaa tcagtttaac cgaagcaggg atcgaaaaag cagaagaaac
    11221 attcggtttg gataacttat acgacattga aaatactgca ttgacccatc acttggatca
    11281 agcattgaga gccaactata tcatgctttt agatatcgat tatgttgtcc aagacggaaa
    11341 agtactgatt gttgaccagt tcactggtcg gatcatggat ggacgccgtt attcagatgg
    11401 acttcaccaa gcaatcgaag ctaaagaagg cgtagagatc gaagacgaaa cgaaaaccat
    11461 ggcgacgatc actttccaga actatttccg tatgtacaag aaacttgcgg gaatgactgg
    11521 tacagctaaa acagaagaag aagaattcag agaaatttat aacatccaag tataccagat
    11581 tccgacaaat cgtccggtta tccgtgatga tcgtccagat ttgctttacc caacattaca
    11641 aagcaagttc cacgctgtcg tgcaagatat caaagatcgc taccgcaaag gtcaacctgt
    11701 gttagtcgga actgttgcgg ttgaaacatc tgagttatta tcagatatgc tgaatcaaga
    11761 acgtattcct catgaagtgc tgaatgcgaa aaatcacttt aaagaagcag agatcatcat
    11821 gaatgctggt caaaaaggtg ctgtgacgat tgctaccaac atggctggtc ggggaacaga
    11881 tatcaagtta ggacttgggg taagagaact tggtggtcta gcagttatcg ggacagaacg
    11941 acatgaatct cgtcgtatcg ataaccagct tcgaggacgt gcaggacgtc aaggagaccc
    12001 tggtatgtca cagttctact tgtcattgga agatgatttg atgaaacgat tcggttcaga
    12061 acgaatcaaa tctttcttag atcggatgaa gatcggtgag gaagatgctg ttatccaaag
    12121 caagatgctg acgaaacaag tagaatctgc acaaaaacgt gtagaaggaa ataactatga
    12181 cacacgtaaa aacgtcttac aatacgatga tgtgatgcgt gaacaacgtg aagtaatcta
    12241 taaacagcga caagaagtaa tcatggaaga aaaaagctta tccaagccac taatgaacat
    12301 ggtcaaacgg acaatcagtc gtgtagtaga tgcgcataca caattagaga aagaaaattg
    12361 gaatttggaa agtatcatcg attttgccgg cagtactctt gtccatgaag atagtattac
    12421 tcttgcagat atcgaaggaa aaacagctca ggagatcaaa gagtatctaa acgaacgagc
    12481 acaagaagta tttaatacca aagcggctca actaaatggt ccagagcaac tgttggaatt
    12541 tgaaaaagtc gtgatcttgc gtgttgtgga ctctaaatgg acagaccata ttgatgcaat
    12601 ggatcaatta cgtcagtcaa tcggcttacg tgcttatgga cagaacaatc cattagtcga
    12661 atatcaaaca gaaggctata agatgtttga agatatggta ggcgccatcg agtatgaagt
    12721 cactcgaatc tttatgaaag ctgagatccg tcaaaacgta cagcgtgaac aggtttctca
    12781 aggaacagct tctcactcag aagacggaga tgccaaagaa aatagtaata ctagcgcgaa
    12841 aaaacagcca atccatgtga acaaggtcgg aagaaatgat ccttgtcctt gtggaagcgg
    12901 gaaaaaatat aagaactgtc atggaaaaaa tgcaaactaa tttctgacag caggattggt
    12961 gagacaaatt ctttttttaa gaattcgtct caccttcttt ctgttatttg ctgattctgt
    13021 tagactagat ataatgaaaa aagtatagtg aaagaaggaa aaaacatgga aatatccgaa
    13081 attcgaaatc tcctgacaga aatgcaggaa aaggtcacaa gcttcaggag gtctctttga
    13141 cttagaccag ctggaagaag acattgcgga agcagaagca aaaatggctg aacctggttt
    13201 ttgggatgat agcgaagctg ctcaaaaagt gatcagtgaa aacaatgcaa ataaagaaac
    13261 ttatgatcaa ttccattctc ttgctgaaga actggaagaa atcgaattga tggtggagat
    13321 gttgcaggaa gaacctgatg cagccatgca agaagaagca gaaacacgta tcaatgcgct
    13381 agatgaaaaa atgaagacat atgaattatc tatgttgtta gatggtcctt atgatcgaaa
    13441 caacgccatc gttgaattgc atccaggggc tggcggaacg gagtcccaag attggggcag
    13501 tatgctttta cgtatgtata cacgctgggc agagcagcat gggtatcaag tagagacact
    13561 agattatcaa gcaggtgatg aagcaggaat caagagtgtg accctactga tcaaaggaca
    13621 caacgcattt ggttatctga aatcagaaaa aggtgttcat cgccttgtac gtatctcgcc
    13681 ttttgactca gcgaaacgac gtcatacttc tttttgttcg gtagatgtga tgccagagct
    13741 tgatgaaacg atcgatatag aaatcaatcc agatgatttg aaaatcgata cgtaccgagc
    13801 aagtggtgca ggtggtcagc acatcaataa aacagaatct gctgtacgga tcactcactt
    13861 gcctacagga acagtagtag ctagtcaggc acaacgttca caattgaaaa accgtgagca
    13921 agcgatgggg atgttaaaag ctaagcttta tcaattagaa gtggaaaaga aagaacaaga
    13981 agcagctgca cttcgaggag aacaaaaaga aatcggctgg ggttcacaga tccgttctta
    14041 tgttttccat ccatattcta tggtaaaaga ccatcggaca aacgtagaga caggaaatgt
    14101 ccaagcagtt atggacggtg accttgattt atttattgac ggctatttaa aaatgcatct
    14161 acaataagaa cccattgtta aattgaaata aaattgtaag attttgcaag catgttgaaa
    14221 cattgccatg ctataatagc taaagactga aaaagatatg gagagaacgc catgattgaa
    14281 atgaaggatg taatgaagaa gtactcaaat ggtacgaccg ctatccgcaa tctctcaatt
    14341 gtcatcgaac aaggagagtt tgtctatgtg gttggtccgt ctggagccgg taaatctaca
    14401 ttcatcaaat tgatgtatcg agaagaaaaa gcttcaaaag gaactttgaa cgtcgcaggt
    14461 catgatctaa tagcaatcaa aaaccgcgaa gttccttatc tacgcagaga aatcggcgtg
    14521 gtgttccaag actataaatt attaccaaga aaaacagtat atgaaaatgt tgcgtacgct
    14581 atgcaagtta tcggcagaaa acctcgggat atcaaaaaac gagtaatgga agtgctggac
    14641 cttgttggtt tgaaacacaa agttcgagtc tttcctagcg aattatccgg tggggaacag
    14701 caacgtgtct ctattgctcg ggcaatagtg aatacgccta aagtacttat cgcggatgaa
    14761 ccgacaggaa atctggatcc agaaaactca tgggaaatca tgaaattatt agatcggatc
    14821 aatgcccaag gaactactgt cgtgatggct acacataaca gtacgatcgt aaatacgatt
    14881 cggcaccgag taattgctat cgaaaacggc cgcattattc gagatcaagc ggaaggggaa
    14941 tatggatacg atgattagaa cctttttccg ccatttatta gaaagtatca agagtttgaa
    15001 acgtaacggc tggatgacag ttgcttcagt cagtgcggta acgatcacat tgactttagt
    15061 cggtgtattc atggcagtta tcatgaacgc aactaaatta gctcaagata tagaaggaaa
    15121 cgttgatgtc tctgtattcg tagatatcgg tacaaaagac gaagagatga aaaagctaga
    15181 aaaagaattg aatgacttag atcatgttaa aaaagttgaa ttttcaagca aagaacagga
    15241 attgaaaaaa atccaaaacg aaatgggtga ttcctggaaa ttgtttgaag gtgacaataa
    15301 cccgttatat gatgtgtatg tagtaagtgc tactgatcct tcttatacaa aacaagtagc
    15361 agaagaagca gcagatttga agaatgtttc tcgttctgat tacggtggag cttcctcaga
    15421 tcggattttc caaatcgctg gtgcagttcg gacatgggga ttagttgcag cggcattgct
    15481 gctgttcgta gcgatgtttc tcatttcgaa cacgattcgg atcacgattt tgtctagaca
    15541 gcgtgaaatt caaatcatgc gtttagtcgg tgcaaaaaat ggatatattc gctggccgtt
    15601 tttccttgaa ggtggctgga tcggtctgat cggtgcgatt cttccgattt tgatcatcac
    15661 atttggttat gcatggtttt tccaattgat caatccatca ttattacgtt cccattattc
    15721 attgattcat ccacaaaata tcgtttggaa aatcaatctt ttaatggtcg gcattggtgt
    15781 gatcattggt tcacttggct cgatcatttc tatgagacgt ttcttgaaat tctaatacca
    15841 caatataaat aaaatgagaa agttggacag tttcgttcca gctttctttt tttattggct
    15901 aggagaatag aaggaagcgg cttttttccc tttactttaa aaaacaactt gggtattctt
    15961 aagttggtag aagaagaggt gaagccgtga aaattatcgt tgacaatttt tttacgatcc
    16021 ttttgattat gaatattttg ctttccttta tcatcgtttt tcgagaaaga aaggaaactg
    16081 ctcaaacatg ggcatgggtg ctcgttttga tgttcattcc agttgtagga tttattttat
    16141 atattttttt aggaagaggg atttccaaag agaaaatctt tgatttgaag atccaaggga
    16201 aaatcggtaa gaacctggaa attgaagaag acaaacaggc attgatgcga gggctttatc
    16261 ctcatccgcc tactggacaa gtagatgtga aacaattgat ctatatgctc acggtatttg
    16321 aaagtacgct ctatacgact aaaaatgaaa tcactttatt tacagatggt cgtgaaaaat
    16381 tcgatgcgct gattgaagat atcaagcagg cagaagacca tatccacttc cagtattata
    16441 tttatcgcag tgatgcatta ggtgaagaag ttcgagatgc attgacagag gcggcaagac
    16501 gaggggtaaa agtcagagtc cttcttgatg catggggttc cacacaagtt tcttccagct
    16561 tttttcagaa tttgaaaaaa gcaggcggag aagtcgcatt tttctttcct ctatttgttc
    16621 cgtatattaa tcctcggatc aattatcgca atcatcgtaa aatcgtagtt attgatggga
    16681 aaatcggata tacaggtggg ttcaatgttg gaaatgaata tctaggattg gtaaagaaat
    16741 ttggttattg gcgagacaat catttgcgta tttacggaga agcggtgtat accttgcaaa
    16801 accgtttttt gatggactgg aattctcagc atacaaaaga agtaggctat tctcccaaat
    16861 tttttccgtc cattcactct actggtgata tagctgttca aatcgtgaca agcggaccag
    16921 ataccgaaca tgaacaaatc aaaatgactt atttgaaaat gatttcgtta gccaaacggg
    16981 agatattgat ccaaacgcct tattacatac cggatggatc gattcatgaa gcactgaagt
    17041 tggctcttct ttcaggcgta aaagttcata tccaaatacc taacaaacca gatcatcttc
    17101 tcgtttactg ggcaacgtat tctttcgctg cagagctaat cgagtatgga gcaaggatcg
    17161 aaacatatga gaatggattt attcatgcaa agacgatgat tatcgatggt ggcattgttt
    17221 cagttggctc agcaaatatc gatgttcgtt catttcgctt ggactttgag gtcaatacac
    17281 tggtttatga tgaacgaatg gcttcacgtg taagaaaagc tttttttgaa gactcgaaaa
    17341 tttctacgca tctcacaaaa gaaatgtatg aaaaccgagg aataatcatc aagatgaaag
    17401 aaggattagc aagattgatt tcgccgctcc tttaaaacat aaaaaggaca tgagaaccat
    17461 caacagatgg agatctcgtg tccttttcta acggggccat ttctgagagt acgtcagaaa
    17521 tggagaaagc gtctcgcatg agcgaaatta actttggggt atctcttgtt ttttggggaa
    17581 agcaagaaat aagctaatat atgctattaa aagagacaca tttcaaagcc agtatagcat
    17641 agaaactttt aatgagatag ttttttttac aattatgaga atttattttg ttatttaatg
    17701 attttgattc gttttcatca agtaatgaaa atgataaaat aaacatactt taggattaaa
    17761 ggagatttct aatgaaaaaa cttaaattat tcttaccaa
//
LOCUS       DAZKNV010000053        17764 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000053 DAZKNV010000000
VERSION     DAZKNV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.053"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(81..788)
                     /locus_tag="ACG8M1_002083"
     CDS             complement(81..788)
                     /locus_tag="ACG8M1_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFQ0422760.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(867..1205)
                     /locus_tag="ACG8M1_002084"
     CDS             complement(867..1205)
                     /locus_tag="ACG8M1_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFQ0422761.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(1316..2278)
                     /locus_tag="ACG8M1_002085"
     CDS             complement(1316..2278)
                     /locus_tag="ACG8M1_002085"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFQ0422762.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(2293..3624)
                     /locus_tag="ACG8M1_002086"
     CDS             complement(2293..3624)
                     /locus_tag="ACG8M1_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFQ0422763.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(3632..4312)
                     /locus_tag="ACG8M1_002087"
     CDS             complement(3632..4312)
                     /locus_tag="ACG8M1_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFQ0422764.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(4531..5010)
                     /locus_tag="ACG8M1_002088"
     CDS             complement(4531..5010)
                     /locus_tag="ACG8M1_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFQ0422765.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(5137..6816)
                     /locus_tag="ACG8M1_002089"
     CDS             complement(5137..6816)
                     /locus_tag="ACG8M1_002089"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFQ0422766.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            7364..8866
                     /locus_tag="ACG8M1_002090"
     CDS             7364..8866
                     /locus_tag="ACG8M1_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422767.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8879..9541
                     /locus_tag="ACG8M1_002091"
     CDS             8879..9541
                     /locus_tag="ACG8M1_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422768.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(9642..9845)
                     /locus_tag="ACG8M1_002092"
     CDS             complement(9642..9845)
                     /locus_tag="ACG8M1_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFQ0422769.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(9956..11140)
                     /gene="iadA"
                     /locus_tag="ACG8M1_002093"
     CDS             complement(9956..11140)
                     /gene="iadA"
                     /locus_tag="ACG8M1_002093"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFQ0422770.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(11297..13036)
                     /gene="yfcC"
                     /locus_tag="ACG8M1_002094"
     CDS             complement(11297..13036)
                     /gene="yfcC"
                     /locus_tag="ACG8M1_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFQ0422771.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(13809..14423)
                     /locus_tag="ACG8M1_002095"
     CDS             complement(13809..14423)
                     /locus_tag="ACG8M1_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0422772.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(15029..15406)
                     /locus_tag="ACG8M1_002096"
     CDS             complement(15029..15406)
                     /locus_tag="ACG8M1_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422773.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(15706..16587)
                     /gene="galU"
                     /locus_tag="ACG8M1_002097"
     CDS             complement(15706..16587)
                     /gene="galU"
                     /locus_tag="ACG8M1_002097"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFQ0422774.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(16630..17649)
                     /locus_tag="ACG8M1_002098"
     CDS             complement(16630..17649)
                     /locus_tag="ACG8M1_002098"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFQ0422775.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         5120 a         3839 c         3017 g         5788 t
ORIGIN      
        1 tattccaaat aaatggtatt caatcagcta actctcggta ttagctcaga tcaaagcgct
       61 gatttcacaa cttctttatt ttaatctctt cggttgccgc cgaacaataa gatcaagcgc
      121 aacagctgca ggaatgtcga aagcgctgct gcaacataag tcagtgctgc tgcaaataat
      181 acgtgtcttg ccatcggtac ttcttcttcc gtcagtagtc cgccttcact caaaatttgg
      241 attgctcgcc gagacgcgtt aaattcgact ggtaatgtca ccaattggaa aagtaatgct
      301 aaagaaaaag cgaaaatccc gatattgatt aacgtagagt tccagctaag caatacacct
      361 accataatca aggggaacga aatcatcgaa ccaaagttag ctgctggaac aagtgctgca
      421 cgaatcttca atgggacata acccgaagca tcttgtaccg catgtccgca ttcatgagct
      481 gctacaccta tcgcagcaac tgaagtagac tgtgcagttg cttgagacaa actcaacatc
      541 ttattacctg aattgtagtt atctgtgaga tctccggcaa tttgttgaac accgacatta
      601 tttatctgtt gactttgtaa tatatattgt gctgcttgtg taccagtcac attgtttttg
      661 cttctcactt gatcgtattt tcggaaagta ctattgacgt acgctgacgc aattccggaa
      721 ataactaatc caagaatgac caaaagaaat gtcggatcta aaaaaccata cattccataa
      781 ccatacattt tcgtttcact ccttttcgtt tactttattt tatcattagt agtaggaaaa
      841 gaatgtgaaa agaccttgaa tattctttaa ttctttttca caaattccga tttcagtttc
      901 atcggtccaa atccttctac cttgcaatcg atattatgat cgccttctac taaacggatg
      961 ttcttgactt ttgttccttg tttaatggca cctgacgcac cttttacttt caagtcttta
     1021 atcactgtca cgctatcgcc ctctaacaga cggtttccat ttgcatctaa taccactaat
     1081 ccgtcttcta tgacagtttc ttgttcttct ttgttccatt cgttcccgca ttctgggcaa
     1141 atcaacaagc ctcgatcttc atatgtgtac tctgagccac attctgggca atttggtaat
     1201 gtcatcttct ttctccttta aaatctttag tgagcactat tgtaacggaa aaagaagatc
     1261 ttgaaaagat acatttgtga tttttactac aaaaggcacg ttttcgaacg aagtatcatt
     1321 ctgtttttct gctcttatac gattggcata tatcttggat ctctttatag atttcctcta
     1381 cttctgctaa atcttttgca ttcgcaccac ttgctaatgg atggcctcct ccatgatggc
     1441 gtttagccaa ttcattgatg atcggcccct tagaacgtaa acgtacgcgg taataccctg
     1501 aaggctgctg aacaaaaatc ccccaagcca gcacttcgtc aatcactcca ggaagtgaaa
     1561 cgatcgaagc tgtctctgaa tcatcgattc catatttatc aagaatttct tgcggaagga
     1621 ttattcttcc tgcaccattt tcatccacct ggatattttg ataaagataa ccggaaagtt
     1681 tagcgacttt catcggcatt tgttcaatct ctctgttcaa agcacttgca tcaaatggat
     1741 aatttctcaa tatcgaagca atctctaatg tacgggacgt cgtggaggga tacaaaaagc
     1801 gccctgtatc tccgacgatt cctgcataaa gtaaccgtgc agccttaacg ttcatcttta
     1861 aagattcagg aaacatcaaa gcaaattctg caatcatctc actacagcta cttgcttttg
     1921 tatttaccca cacaagatct ccataagggt catcattggg atgatggtcg attttgatca
     1981 gtttttctgc caactgatat ctttgatcac tgattctggg tgaattagct gtatcagtca
     2041 cgatgactag cgctccttgg tagaagacat cttcaacttc ttgcatttct gctaaaaagc
     2101 gaagcccttc aatcgtttca cctacttgac gtatttcttt ttctgggaaa ctttcccgta
     2161 atagttcggc taatcctact tgtgatccta atgcatcagg atcagggcgc aaatgcctgt
     2221 ggataatgat tttatcgtat ttttttattg tatctactat ttcttgctgt actgtcattt
     2281 cactcctgct ttctaagaac gttccattac ttgacaaaca acgattgctt tggaaacgat
     2341 ggtgttttca ataaacactt cgatatccag tttagcggaa cgtctgccga tttccaatac
     2401 acgtggacga atgtctaatt cgctttccaa ttggatcagc cgcaaataat gtaggttcac
     2461 ttgttcaatc aagatatttc gtttttggtt catcaccatt gttttttgtg cgacatcaga
     2521 aatgatttcg ctaagtacgc caaaagaaat ggttccaacg ccattgacca tttgtggtgc
     2581 tactacgaat ttgaacttag ggttttccaa acgatttcct tcacggtcag tatcaatcgt
     2641 atggatattt ccagatatct gatccgaaat cgtatctgca atctgcggtt gtcgctggac
     2701 aagctgcatc gctttcatta catcttgccg ggtaatcaag ccttccaatg tcaagtcatc
     2761 ggaaacgacc ggcatgactt ctagcccatc ccagatcatt tgatggctaa cagaggcaat
     2821 actcattgtt ttctttacac tgattggttc tttcgtcatc acccgatcga tgatctggtt
     2881 tggcgatttc cctaaaacat cttttgccgt aacaatcccc atcaaacgat gatggcggtt
     2941 gacgactgga aaacgcgaat gctgcgtttc ttctgacaaa cgctgataat cagaaatcgt
     3001 atctgtctgc tgcaaataat gagtcttttc agctggcata tagatatcac tgacaagcat
     3061 gatatctttt ttgatcaatt ggtcgcttaa cgctcggttg atcatggttg cgactgtaaa
     3121 tgtatcataa gaggtgcgta agatcggcat ttcaagatca tcagctagct ttgcaatctc
     3181 agcagtcgta ttgaatcctc ctgtgatcaa tactgcggcg ccatcttcca atgctaattt
     3241 ttggacttcc gcccggttgc cgacgatcat tagtgatcct ggcgtaatat agcgttccat
     3301 ggcatgttta gtcatcgcgc cgatgacgaa tttattcaag accttgtcta atcctgccgc
     3361 cccgcctaaa acgtcccctt caatgatcct gacgacctcg ccaaatgtca aacgttcaat
     3421 atgttttttt aatttgcgtt cgatacggat ggtccctact cgttgaattg ttgaaactag
     3481 tccgacattt tctgcatctt tgattgcacg gtacgctgtt ccttcactga cattcaattc
     3541 ttttgcgatg cttcttacag aaattcgatt gccaacaggt aaactttcaa tatattctaa
     3601 aatcaaatca tgttttgtcg ccattttctg cctacacttc cagcgtttcc gagacgctca
     3661 ttatttttcc ttcactatct tccagtaact ctacaaaaga ttcgggatct tgttcaatga
     3721 cagggaaagt attgtaatgg attggaacta ctttcttggc acgaattgtt tgcgcagcct
     3781 ttgctgcatc ttctggcccc atcgtatagt tatcgccaat cggcaagaaa gcgacatcaa
     3841 tatcgaattc ttctgcaagc aatcctagat cactgaaata agcagtatcc cctgcatgat
     3901 aaatcgtttt tccttctgct tgaataataa ttccgctagg ctcgcccata tactgaacga
     3961 taccgtctac ttcatagctt gaactatgct gtgcatgtac gaattttacc acgccgaatg
     4021 gaaacgcatg ttttccaccg atattcatac cgaatgaatc tactcctctg ctgttcgcat
     4081 aatcagcaat ctcaacaata ctgataattg tggcttgatt ttcttttgca ataggaatca
     4141 tatctcctat gtggtcacta tgaccatgag taatcagcaa ccaatctgtc tttacttctt
     4201 ctgcagttaa gtctgtcaat ggatttcctg taataaacgg gtcaatcatc acgcgttggc
     4261 cattttccat ttcaattgtt aaacaggaat gtccatgata cgtaattttc atattttaca
     4321 cctcgcgttt tctctgtatc ttttttatta aaaacgattt catcacttgc acatcaatga
     4381 aaaaatatag ctgctaaata tattttcatt ggattgatag tacagtatgt acaaagcaat
     4441 tgtaacagat aatacaggat gcaccaagta ccaagcagat ataatctcaa gtttgaggtc
     4501 tctgctctgc ttagcttctc ttctcgtccc ttaactaatt aaatcagcgt aaataggatg
     4561 gacgatcttt tctaaatcgg ctacttttat ccgaaggctt ctcccgattt caccgcttga
     4621 cacaattact tcttcttttt cttttaaaga actgtctgct aaaaaacaat aatcaggatg
     4681 tgcgagtttt attccaatag gggtgtttgc tccgtgggga tatcctgtat gcattaatac
     4741 aaaatccatt ccaggaaaac caactttacg atctttcgtc acttgtctcg tttttttgta
     4801 atctaagtga tcgttcaaag gaatcaatgc gatgatcacc ccagttttgt ttcctttcac
     4861 tacgagagtt ttacatatca aagctggatc aatccctctt ttttgtagtt cttctgtgaa
     4921 agattcttct accacatgac taaaatcaag tggttgatag ctgatctttt gttcttctaa
     4981 ataacgttcg acttttgttt gactcatcat tgattcactc cctttattct atcgtttatt
     5041 ataaagcgag ggatgctgta ttcaaaaatt atttgttttt cgcaaaaaaa gagcaagacg
     5101 agcactctat agagaggttc atcttactct ttttgtttat tttttatttc gacgttgagt
     5161 agcttccata atgactggca agatcactgg gcggcgtttt gtttgttcaa ataagtaacg
     5221 gcctaattga tctcggatgt cttgctttaa tttgctccac tcaaaatcat tgctttctaa
     5281 atgtttctca acgattgttt caatcatatt gctgctttct ttcatcagat cacggctagc
     5341 ttttacgtaa acgaatcccc gtgaagtaat ttgaggtttt gaaatgattt tcttttctcg
     5401 ccgactgata gtgacaaccg ctacgaaaat cccgtcttct gacaagattt ttcgatcacg
     5461 taaaacaatg tttccgatat cacctatgcc taatccatca atcattacat tttctgcact
     5521 tgtagttcct gcaacactca tacgcttgtt cttatattcc agcacgtctc cgcgtccagt
     5581 aatatagata tttttgtatg gcatccctac tgcatgagcc aaatctgcat gagcagctaa
     5641 ttcacgatac tctccttgaa ctggcacaaa atatgttggt ttcatcaaat tgatcattaa
     5701 ttgcaagtca ttaggattgg catggccaga aacgcgcata ttctcagaga tcaacttcac
     5761 tgttccacca gctcgataaa tgatatcttc cgttttcgcc acgatggttt ccatcgcgat
     5821 gcttggcgta gtagtgatat aaaccaaatc tccttcttca atcttgacat tacggtgtgt
     5881 accgtttgcc attttttgca gagacttgat gggttcaccc attcggccag tttctaaaat
     5941 gatcagttct tctggatcat agtttttcat gtctttcaac gtaacaagca gatcttcact
     6001 tggtaattga agtttttcta aacgcatcgc tgtgcgaata attcgttcga aatcttgacc
     6061 agtcaagaca acttttcgtt gtgctttttc tgctgcatcc aatacttgtt gcactcgttg
     6121 caaattactt gctacacaag cgacgatgat acgcccttcc caatatttga tcgtatcaaa
     6181 tacttcatct gctatttggg cttcagaagc tacaggctga ggattttctg catttgccga
     6241 ttcacttagt aaggctaaga ctccttcttt gccgatttcc gccaatcgtg cataatctgt
     6301 ttgatacatt gggatagccg tttggtcaaa tttaaaatct cccgtataaa cgatactacc
     6361 ttcttttgtt ttcagattga tccccactga atctggtatc gtatgagtgg tacggaaaaa
     6421 gctcactact gtttcaccaa agtctatttc tgtatgctca tctaccacat ggaaatcctt
     6481 aaatcctttg gctgcttcat tacgactgac attcaatttt gctaactcga tcgtcaactc
     6541 tgtcccgaat actggtacag aaatttttga caacaagtaa ggaagtgccc cgatcgcatc
     6601 tgcatgtcca tgtgttaaaa agacaccagc tacacgatca atgttttctt ctaaatacgt
     6661 aaaatcaggg attacgacgt cgatccccaa caactcattt tcaggatatt ttagcccaca
     6721 atctaaaata aaaatatcct cgcccacttc tgcgacatac atgttttttc cattttcacg
     6781 aacgccgcct aatgggataa ttttaatggt actcacaaac ttcacctctt cttatgacat
     6841 ccaagtttaa agatgtcgat tttcttcttt atctaaatat atgagccatt ccaatgaagc
     6901 atatgcaaaa tcactatttc tcaacttatg gagaatcagc aggaaaatta ccagcacatc
     6961 cgcgttctga cagttggatg ggcattttat tttggatata cttcattaac aaaatggatc
     7021 ttttgcgaaa cgctatagcc agaatactta tataagtatt cagctgttcc ccattattat
     7081 acaacaaata aactaaatcg ctagtatcag caattgttag aacaactatg cacgtaaaaa
     7141 tccctctgta gcatctagga tttcttttgc tattcctctt tcatttcttc ttcgtcggtt
     7201 tgaaacatac ttttttcatt ttaccacatt ttttgcaata actatagtga ctttttatat
     7261 atacagaacc tcatgttgat ggtgtgcaaa cagcataaga tttaagctag ctttaagata
     7321 ggttgtctat tatcaaatgc atctactagg agggatgcaa aatatgaatt ttatgaaacg
     7381 tgcatggaaa agtacaaaag taaaatgggg acgttcattg ttattgtttg ccgtgttcac
     7441 agccattctt atttttgtgc tagctggcct cacgattcga agcgctgcag aagaagcagc
     7501 gaatcaagca caaaaagaag ttggagcaac agtgacttta agtgccaatc gagaagcttc
     7561 atttaaaaaa caggaacaaa cttcttcaag cggttctacc actgaagaac gtccagatcc
     7621 aggcagtttt tctcttacac cagtttcctt aacggacgcg gaaaaaatag ctgaattaga
     7681 taatgtaaag agttattcct ttgaaagttc cgcctcagct atggcaaaag atggaataac
     7741 tgccatcact agttctgatt caagtgaaga cagttcagaa actactgatg caggcggtga
     7801 acctgctgga ggaatgggcg ggaatccgca aatgactcaa gcagactttc aaatcagtgg
     7861 tgtgtcagca actgcacaaa atagtaattt ttctgatgga acagcaaaaa tcacggatgg
     7921 tgaaggaata gatgacagcg acaaaggcac aaacaatgta gtcattgatt ctactctagc
     7981 agaaacaaat gacctggcag tcggagatac tttcacaatc acgagtactg aagatgaaga
     8041 taccacttat gaaatgacga tcaaaggaat ttatgaatcc agcgaaacaa gcggcagtat
     8101 gggtatgaaa ttcaacttca tgaatccgtc gaatacactt tacacttctt acacttttgc
     8161 aaatgaacta aatgggacat ctgacgataa cacgatagat tctgctattt acactctatc
     8221 tgatccagat aaaatggatg agtttctcaa agaagctgag aagctgatcg acacagatac
     8281 atttagctta caatcaaatg attccatgta tcagtcaatg ttggaacctt taaacaacgt
     8341 ggcaagtttt tctaaaaatg ttgttttact agtgactgta gccggtatta tcatacttac
     8401 tctgatcatt atgattacca ttcgggagcg tcggcatgag ttaggcgtct tgctatcttt
     8461 aggagaatcc agaagtaaaa tcattctcca attgtttacc gaagtggcta tttgtatgat
     8521 tcttgcatta ggagttgctt cgcttagcgg aaacgtcgtc gcgaatgccg tgggacagca
     8581 gctacttgac caacagacag aaaccacgac acaaaaccag caagctcctg gcggtggaca
     8641 aatgccaggt aacagacaag aacaaggcgg tcaacgcgat ggtcaacaag gaaccacgaa
     8701 taatccattt gctgtttctg atcaagtcag cgaattggaa atcaatgtca aacctgcaca
     8761 attgggacta ttagccggag tagcatttgg aatcagtctg ttttctgtct ttttagcttc
     8821 tatagggata ttaagattaa acccaagaaa aatcctatta aactaaagga ggaatttgat
     8881 gttacggaca gaacaattgg gattttggta tcaagatccg caagatgcgc tttataaaga
     8941 tgtagaactg aatttcgaag ctggaaaaat gtacgctatt ttaggagcaa gtggttctgg
     9001 aaaaacgact tttctttcgc ttatttctgg actagatgca ccaaaagaag gaaaggtata
     9061 ctatcaagat cgttcactga acaaaatcgg gttaagaagt tatcgtaaaa atgatgtctc
     9121 gattattttc caagcttaca acttgcttcc ttatttatcg gctctagaca acgtcatagc
     9181 agcaatggaa atcactaaga ccaagcaaga gaattatcga caagttgctt tagatcgact
     9241 ggctcgtgta ggaattgatg aaatattagc aaaaaaacag gtgaccaaac tttcgggagg
     9301 tcagcagcag cgagtcgcta tcgttcgtgc tatctgctgt gaacatcaac taatcgtagc
     9361 ggatgagcct actggaaatc tagatgaaac aacttcacaa gatatcgtca aacttttcca
     9421 agaaatcgcc catgaacaaa atcgctgtat tatcatcgtg actcatgaga ttgaagtagc
     9481 aaaaagctgt gatgaagtct ttgaactaaa aaataaaaaa tttcaaaaaa tcgaagttta
     9541 aaaaacagga taatgatcaa ataaaaaatc cgaaccatat ctgtctcgca gatatggttc
     9601 ggatttttta tttgcttgat tcaattagta ataagtggtt tttatttttt ttcgtctttt
     9661 cgagaaaact tgtctttgac ttcgtcgcct aaatttcgag ctttttcttt gatgtcagca
     9721 cctagtgatt gtgctttccc ttctgtttct ttgctcttgt cgtctgttgc tttgccgtat
     9781 gcttcttttc cttcaccgac tactttatct ttcatatctt tagaacgtcc ttttaaatct
     9841 gccattgtgc ttcctcctct tagtttgttt attgatctac cttcagggta acatcaacaa
     9901 cagatacaga caaacagaac gctcgttttc taaaaaagat agttagagct gttgattaaa
     9961 aacttttttc gaaagtcccc catactttga cttctttttc ttggaccatt atttctcctt
    10021 tagcgataac tgtatcaata tcaagcgttt ctttatccaa gatacacaga tctgcatcag
    10081 caccaatttc gatttttcct tttttatcca atttcaatat acgtgctgga ttactggtta
    10141 tagctcgtaa ggcgatttcc aaagggatac tttctttttg cacagcttct ttgatcccta
    10201 ctagcaatgc cttggcactt cctactccta accctaggaa atgattgttt tcatcaaaat
    10261 aaggcaagct tccttgtcca tctgaggtca tcgtgaaatt atctaaagaa acatcttcct
    10321 cgatcaatcg tttcagtgct ttgctgaagc gaacttcacc atctgtcttc tcccaaaaat
    10381 caggatcttc gctagcagtg aagtcaatcg tgccaccacg tttggcaaat gccacgcaag
    10441 cttcaaataa ttctggtgtg cgatttgcat gagtaggcaa aaattgtgtg atcggaattt
    10501 ctgtttcttc tacgattcgt gtcaatagct ctagctttct ttttcctccg cctaagtgga
    10561 cattgatgat cccagctttt ccggataaca tgcctcctac acgagcatct gctactgcac
    10621 gagcgaactc ttcaaaactt ggctgagaag aacggtgatc ggatactgcg atttctccga
    10681 ttccgataat tttatcaatt gtcaaaaagt ctttgatgat agaatctgtt actgttttta
    10741 ccggcaatcg gtacgaacct tcgtatacat aagtggagat tccttctgct tccagacctt
    10801 tcgctttgct gatcaacgca gtcatatctc taccttctcc gtctgttccc aaacaaccga
    10861 caactgtcgt tacaccagct gtagtcaatt ggctcaatgt gacttctggc gttcgatttt
    10921 gataaccgcc ttctcctcct ccacctaaaa tatggaaatg acagtcaatg aaacccgggg
    10981 ttagtacttt tccctcacct gaaagttctt ctacttccac tccttcgtag ccgccttcta
    11041 gctgttcttc tacagccaaa atcttcccac cggcaatcag tacatccatt tttcctaagt
    11101 aatctggtgc aaacacttca atttgtcgaa tgattttcat acatttttcc tctttcttta
    11161 agtataactg atgataggat cttaaaaaat aatccaaacg ataggatctt tactcctttg
    11221 attttaccgt aaaatgacgg ttcttggagt ccttatctac tgtttggatt acttttttat
    11281 ttacaggtct ccagtactac tgcagaccta ttgcaatggc aatcatgatg aaaatagttc
    11341 ctaaaacaaa caggaatcct tgcatcttga tttggaatct tgcccatttt gcccattcga
    11401 tccgtgcaac acctagcaca ccaatcaagc tggctgatac gggtgtaaaa gcgtccataa
    11461 aacctgaacc aagctgataa gcaagaactg ctacttgtct ggatacacct actaaatctg
    11521 ccagtggagc catgattggc atagtcaaag ctgcttgtcc tgaatttgat gtaacaacca
    11581 agttgaacaa actttggaag atgtacatcg cccaagcacc aatgacagct ggaacaccgg
    11641 tcaacgccgt cccgatccca tgcaaaatcg tattcaaagc tgaaggaaca gatgcatcag
    11701 atcctcccaa gacaagaaga atccctttgg ccatacctac tacgattgct gtaccagcta
    11761 aatcagctgc accagattgg aaagaagaag cgatgtcatt gactttcatt ccatctaatt
    11821 tgaaaagaac agcaatgatt ccagcaacta atcccatcac aaagaattga gaagcgattt
    11881 ctggaatgta atagcctttt tgagtcacgc cccaaacgat ccagacaagg acaactaaca
    11941 tctctaataa gatcaattta tgcccaagca tgaatttttt attttcatca gatgtctttt
    12001 tgatatgaga acggaaataa tcatctgatt tgtaagtcaa cgaactttct ggttttttac
    12061 ggattttttc tgcatatatc atcatataac cagcggctaa tgcagtaaca actacccaca
    12121 taatcaatcg gaatgtcgca ccagacaaca cggggattcc agcaatccct tgagccaccg
    12181 ctacgctaaa cgggctcatc caagaggtcg catttccgac ttgagatgcg acataagtca
    12241 cggttactgc tacgatcgag tcatatccta acgcaatgac aaatggaacc atcaccattg
    12301 agaatggaat tacctcttct gccatcccga atgtagcgcc accgaatgaa aaagcaaaga
    12361 ataatagcgg taaagctaaa cgctccagtc ccttagtttt actgataaac gcatagatac
    12421 ctgcgtcgat cgctccggta cgcataataa taccaaaagc acctccaaca acaaggatca
    12481 atgcagcgat ccctacagca gatccatact tatctccaga tactagtcct tcaaaaacaa
    12541 aatttaagaa accaaagccg ccaaaatcat ctgttcccca tattttggct gttttatgca
    12601 attttttaga agtatcatag atattttcgc cgtactgatc gtaaagcaca tcatctgtca
    12661 aggagatttc atctagtttt tcctgcgtaa gatttttttc tccgtcagca atgacttttt
    12721 ccaatccttt ttccggaaca tccagttttt cacgttctgc tggatgatct tgcagttctt
    12781 ctaattgatc aaacacatac gacttatcca gctcgtaagc ataacggaag gaatcttgac
    12841 gtaaaacagt acgagtactt gtttcgccat ttgcatcttt gtattcaata tcttgcgtgc
    12901 tgaactttcc tgctggaacg acaaaagtca gtatccatgc aaagatgact acaccaaaaa
    12961 taatgacata cgtatggggt gtcgataatt tagtgaagtc gcgtttcggt tttcctgaag
    13021 aatttgtttt cttcaaattt atttcttcct ttcttttttc agtaattttg atgaataaaa
    13081 aatggataat caaatgaatt atacagtaaa aatgacattt ccacatgaat aatttattag
    13141 aaaatcactt ttttctattt tgtttttttt ctcctatgta tgattatttt tttctctttc
    13201 catttatatt aagtatttta tttctctgtt tttccttaaa attctttttt tatttttaga
    13261 ttagagaaaa tctcgtcctg tttttttcat tttacaatca ttgaaaaatt gaatttcatt
    13321 gcaaaaaaaa taataaacac ttataaatat ccattatcta tccttcaatt tttgtgtatt
    13381 ttatttctat tagaaaaagg tatcctgttg gacaattttg ttatatcagg taaacttcat
    13441 tgcaataatg ataacaaatg tactataatt actttgtaaa gagttttggg gaagactctt
    13501 tcatcaacgt gtattaagag acaagaaaga atccatatgg attctttctt gtctcttttt
    13561 ccactacttt ttatttttct gacactacat attcttataa ctcatttctc ataactgtga
    13621 aacaacttat aaaaataaca aactttaaac aaaacaagct taaaatcaaa gatgatccat
    13681 cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc ctcattaata atcgttttct
    13741 ttttttcaaa cgctccattt ttatgtggaa cattattttt ttaaggaact ttgtcaacat
    13801 gtggataact attttccact tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact
    13861 tgctgcagca aaaagatcgt tgcaagagag gctgttccgc agatcgctgg atctagattt
    13921 ggcaaagtca agactgcatc atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat
    13981 tcaaataatc gcaaaccact gctatgttgc gatttgatac ttcgtgacaa atcaaatcca
    14041 gtaacaatga ttaatggatg accattttct ttgatccact gagctagttc gatgattgcc
    14101 gggtttcttc cttcattcga aagaagaaga aaaatgtctt ctgatttgac agaaagctga
    14161 tcaataattg cctgtcctgc accttctagc gtttcataga cacctccggc tggattttca
    14221 atcaatatac ttggtacaag atccggggtt tgatcccaaa attcaaatgc tacaccactt
    14281 agtgtgcggc tagcatatat ctgcaatcta ccaccttgat taatttgttt cgcgatccaa
    14341 gtgccagctt gaagcatcag cggctcttct atccttaatt tctcttccaa ttggtgataa
    14401 tagtcaaaat aacataaact catttatctc tcccgcctag ctatacttga catgaataga
    14461 aacagctgcc taatctaagg aagtacataa aaaaacagta gttagacagt aacacatgtg
    14521 gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat acgcccaata ccttgacata
    14581 gcaaataaaa caacgtgcag accatggaaa atatctacat aggggtagaa ttttcaccct
    14641 agattaggta caataaatta ggtcgatgca ctgcattgac tatggcaaaa tgatcggtca
    14701 gggtgtatgt gtgtgactgg tcattccctg attcttagcg ccaactaagg gtcagggagc
    14761 ctttttttat tcagctgttt ctatctgaat ttattgtaag taatctctta tccaagtgca
    14821 agcaagaaaa tacaaaaaaa cattggtatg atttatatat atataaataa cataaaaaaa
    14881 ggaatggctt atcccgatac aacaagcatt cctttaaaaa agattctttt atataagtga
    14941 aaaaagcttt tttccaccaa ttaaataaat ctctcatctc aatagtttat ccattatttt
    15001 atcttttttt gcgtatacct actaaatatt accgtcttct tctcgttctt ctactttgtt
    15061 cgagagaatc tgtactagaa aaagtagttg tatgtctacc ttttctgcct atccgagact
    15121 ttcttttcat atatgggata taaatgatta gatacagtac agcaaaaaat aaagcaaata
    15181 cgcaagcttc ccaactacct aacgccaatt caaccatcaa ggtagcaacc ccaacggatg
    15241 ctgcatacca gataaaaatc agaaacgttt ctttttttct gaccatgcga aacatgataa
    15301 atagactaat aagcaatagt ggcaacacaa atatccaatt gcttccttcc atcagccact
    15361 tgagtatatc aagcagcgac tgtgcaacag cgactaattt tcccatagtg aacacacacc
    15421 tttttttata attaaaaaat tcgccttttt attctactat gaatcttctg gcttggcttt
    15481 catttctctt atgtaatcat tttcttttat acaacttaaa aaaaaattaa accattagca
    15541 taatattttc tgaatctatt cacgaaagtc tttttctatc tttcgttttc cacgactcaa
    15601 ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt
    15661 taataacaaa tagcctttca ttctcagcag gccacttatt tccagttaac tttctgttct
    15721 tagcttttta ctcaactgga taatatatgc acttaatgaa gtcccaattt ccgaatgttg
    15781 aagtccatat tcaatatttg tcttcatata tcctaactta tcgcctacgt cgtatctttt
    15841 tcctttaaac tctctcgcat agaccgcctc tgtctggtta agagtctgaa gtgcatccgt
    15901 tagctgtatc tcgtttcctg ctcctggttc ttgagtttct aatatctcaa atattttagg
    15961 agtcagtaga taacgtccga taatggctaa attacttggt gcttttccca tttcaggttt
    16021 ttctacaaac ccttttactc tgcaacgacc cttttcgcta tctgttttag gatcaataat
    16081 tccgtattta gatgtttcat tttctggtac acgcatgacg gcaacagcgg aagcttgtgt
    16141 ttcttcataa tccatcatca attgttgagt caatgggata tcatctttca tcaaatcatc
    16201 ccccagcatg acgacaaacg gttcatttcc tataaatgct tttgcttgaa gcacggcatc
    16261 ccccagtcct cttggatgag attgacggat gaagtgaaga ttgacttgag tcgtttcttc
    16321 aactaaagcg agtaattctg ttttttcctt ttcccgcaaa ttgttttcca attcgatatt
    16381 tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc gttacgatca agatgtcttc
    16441 gattcccgaa tccaatgctt cttccacaat aaactggatc gttggtttat ccacgattgg
    16501 aagcatttct tttgccatgg cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc
    16561 aggaatgact gcttttttga ccttcacttg ctgttcctcc taaacgacga ttaactattg
    16621 atcatctatt taacgaagag aaaattcatt ctccattttt ccgtcacgta acatgatttc
    16681 ttttgctgct tttttgatat cttctccatt atacaaaaca ttatagattg tttgagtaat
    16741 tggcatctca acacctagct gttgagctag ctctactgct gcttttgtcg ttgccacacc
    16801 ctcaacgacc attcccatgt tttctagaac ttcttccagc ttatgtccct gtcctaacaa
    16861 gttaccggca cgccaattgc gagaatgaac acttgtacaa gtaacgatca agtcccccac
    16921 accactcaaa ccgataaatg tcagaggatt ggcacccatc gcgacaccaa gacggctgat
    16981 ttctgccaat cctcgagtca tgattgctgc ttttgcatca tctccgaatc ctaatccatg
    17041 gatagcgccg gcaccaattg caatgatatt tttcagtgct gcaccagttt ctacgccaat
    17101 cacatcatta tttgtataaa tcctgaaata atcattcatg aacagttttt gtacataggc
    17161 tgctgctttt tgatcaatac ttgcagctgt aattgttgtg atatcatgta ctgccacttc
    17221 ctcagcatgg ctaggaccag ataatacaac aattgcctgt cttttttctt ctggaatttc
    17281 ttcagccaaa acttctgaga ttcgtttatg cgtatcttgt tctagtcctt tacttgcatg
    17341 tataatgatt ggcttagtat tcattttacc aataagttcc tgtgcgactg aacgaatcgc
    17401 ttttgttgga acaacaaata aaatagcatc tgcgttatcc actgcttctg ccaattcttt
    17461 atatccgata atcgattctg ggatcgtcaa atcaggtaaa aaatgctgat ttgtatgata
    17521 cttattgatt tcatcaatct gttcaggtac atttccccaa atacggacat catgcccgtt
    17581 ttctgccaat gtttgtgcta aagcagtgcc ccaagatcca ggaccaagaa ctgcgatttt
    17641 ttgtttcatg gatattcctc caaataaata attgataatt tccattatag tatacatttc
    17701 ttaaagttgg gactaatttc cattgttttt aagtgtttgt ttacttcttt tatcgttttt
    17761 actt
//
LOCUS       DAZKNV010000054        17167 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000054 DAZKNV010000000
VERSION     DAZKNV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.054"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..848)
                     /locus_tag="ACG8M1_002099"
     CDS             complement(39..848)
                     /locus_tag="ACG8M1_002099"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0422776.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1141..2577
                     /locus_tag="ACG8M1_002100"
     CDS             1141..2577
                     /locus_tag="ACG8M1_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFQ0422777.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2747..3943
                     /locus_tag="ACG8M1_002101"
     CDS             2747..3943
                     /locus_tag="ACG8M1_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFQ0422778.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4005..4190)
                     /locus_tag="ACG8M1_002102"
     CDS             complement(4005..4190)
                     /locus_tag="ACG8M1_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFQ0422779.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4421..7735
                     /gene="dnaE"
                     /locus_tag="ACG8M1_002103"
     CDS             4421..7735
                     /gene="dnaE"
                     /locus_tag="ACG8M1_002103"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFQ0422780.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            7903..8865
                     /gene="pfkA"
                     /locus_tag="ACG8M1_002104"
     CDS             7903..8865
                     /gene="pfkA"
                     /locus_tag="ACG8M1_002104"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFQ0422781.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8939..10723
                     /gene="pyk"
                     /locus_tag="ACG8M1_002105"
     CDS             8939..10723
                     /gene="pyk"
                     /locus_tag="ACG8M1_002105"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFQ0422782.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10758..11660)
                     /locus_tag="ACG8M1_002106"
     CDS             complement(10758..11660)
                     /locus_tag="ACG8M1_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0422783.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11846..12415
                     /locus_tag="ACG8M1_002107"
     CDS             11846..12415
                     /locus_tag="ACG8M1_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFQ0422784.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12473..12652
                     /gene="rpmF"
                     /locus_tag="ACG8M1_002108"
     CDS             12473..12652
                     /gene="rpmF"
                     /locus_tag="ACG8M1_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFQ0422785.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12822..14243
                     /gene="gndA"
                     /locus_tag="ACG8M1_002109"
     CDS             12822..14243
                     /gene="gndA"
                     /locus_tag="ACG8M1_002109"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFQ0422786.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14436..15122
                     /locus_tag="ACG8M1_002110"
     CDS             14436..15122
                     /locus_tag="ACG8M1_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0422787.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15119..16624
                     /locus_tag="ACG8M1_002111"
     CDS             15119..16624
                     /locus_tag="ACG8M1_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0422788.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         5554 a         2979 c         3593 g         5041 t
ORIGIN      
        1 attgtcacaa cctctttttt gtggaatcta attctctatt atagtttaag tagtttttcc
       61 agataaacag ctaaaccgtc ttcctgattg ctcaaaggag tgacatcatt tgcaatgcct
      121 ttgagttggt cagtaccgtt agccatagct actccccaac ctgcataatc caacaattcc
      181 aaatcattat gctcgtcacc aaaggcaatg acgtcttttt gatcgataga caggtagtta
      241 gcaatctctt gcacgccttt tgctttttgg attccttttg aaacaatctc taagatggca
      301 gtaggtccac cccatgtccg aacatcgaca taactgccaa attgacgtgt taattcagca
      361 gatacagctc ctgcaaaacg tttgtctgtt cggacaagca aagatgtagg atttgtcgtc
      421 aaatttttag gagaaagcaa attcttctct cctggacgag aagaagcaaa aattttttca
      481 tcaaagaaat caaaactgtc aataaaaaaa gtatcacgat tttcagcagc gataaaatct
      541 aaatttagct gctttttttg cgataagatt tcaaaagcga tttcacgatt gatcaacgtt
      601 tctctttcac catcccagtg ctgattaggg atgtgtacta atgcgccgtt aaaattaacc
      661 atcggtgttg ttaattctaa ttgttggtaa aactgatggc tcattcggaa tgggcgtcct
      721 gtagcaatac tgacatgatg accggcattg attgcttttt ttagagtctc ttttgtttta
      781 gatgtaatca tcgaatcttg attgagggta gttccgtcca gatcgatggc aattaatttt
      841 ttattcaata agggtccttc cttcctcaac tagcatttgt tttagtctag catattttag
      901 gtaattaaca agagcaatca gctattccta acaaaaacta cagttatggc tatataaata
      961 gctaaacata agctaaacac gaacgttaag tattattttc gctttttttg ttaaaaaaac
     1021 gttgaaaagc gaatgaaacg tctatataat ttgaaattgt tcgatggatt tgccctattt
     1081 tacttatttt ttattattat agttttccat cagaaaaaaa ttcagggagt ggaacttttt
     1141 atggaaaagt ttttcggttt aaagaaaaac aatacaaatg tatcaactga aataatggcg
     1201 ggagtaacga cattctttgc catgagttat atcttattcg taaatccgac gattttgtca
     1261 gcatcaggta tgcccttcca agcagtattt ctagcgacaa tcattgcatc gattattggt
     1321 acgctggtaa tgggattgtt cgcaaatgta ccatatgctc aggcacctgg tatgggattg
     1381 aacgcatttt tcacttttac ggtcgttttt gggcttggtt attcttggca acaagccttg
     1441 gcaatggtgt ttatttgcgg attaatcaat atttttatta ctgtcacaaa tattcgaaaa
     1501 atgattattc gggcgattcc cgaaagtctt caacatgcga ttggtggcgg gatcggtatt
     1561 ttcgttgcgt atgtcggaat caaaaatgca ggattcttat ctttttcagc agaccagtca
     1621 gctatttcga gctctgtcgt tgaaggcgga aaagcgacaa atgttacgat aaatggtgga
     1681 atcgtccctg cgttagccaa ctttgacaac gctcctatct tattggctgt gattggtttg
     1741 gtactgacag ccattttagt tgtaaaaaat gtccgtgggg ctattcttat cggtatcgta
     1801 gcgaccacag tccttggtat ttttatgggt gttgttgatt taagttccat tgattggcaa
     1861 acgaattcgt taggtaattc atttaaagaa ttaggaacaa ctttcggtgc agcatttggt
     1921 tctgaaggca tgcaatcttt attcagtgat tcttccaaga ttcctcaagt attgatgacg
     1981 atcatcgcat tcagtttatc tgatactttc gatacgatcg gaacatttat cggtacagga
     2041 cgccgcacag gtattttctc aaaagaagac gagatcgcgt tggaagatgg tcgtgggttc
     2101 aaaacaaaaa tggataaagc actatttgcc gatgcgatcg ctacttctgt gggggctatc
     2161 tttggtacat cgaatacaac aacttatgtc gaatctgcag ctgggatcgg ggccggtgga
     2221 cgtactggtt tgacttcagt agtagtggca gtgctattcg cattaagtag tttattctct
     2281 ccactgatcg ccattgtacc aaatcaagca actgcgccag cattgatttt agttggagta
     2341 atgatgatgg cttcttttgc agacatcaaa tggctagata tggaagaagc tttaccggcc
     2401 ttctttgcat cgatctttat gggattgtgc tatagcattt cctatgggat tgcagcagga
     2461 tttattttct atacaattgt gaaagtaatc aaaggaaaat acaatcaagt ttctgttgct
     2521 ttgtggatcg ttgatatttt attcattatc aacttcatca ttctagcaac aatttaacta
     2581 aagagaaggg attggaacag tatttgttct gatctctttt tgttttacat aaaaagaacg
     2641 ttacatataa aatgaccttt gcgggatttt tctcttttta ctggcgagat cgttgcttgt
     2701 ttattcgaaa ataggtatga taaaagagac gaaagaggga tgatagatgg agattaattg
     2761 gagaaaaaat ttagtgattg cgtggattgg ctgttttttc actggtgcaa gtattagttt
     2821 agttatgcca ttcataccag tttatgttga gcaactagga acaccaaaag atcaaatcga
     2881 attgttttcg ggactagcaa tctctgtgac tgcttttgca tctgccgtgg ttgcaccaat
     2941 ctggggaaat ctagctgatc gaaaaggccg aaaactcatg atgatccgtg cagcagcagg
     3001 gatgacatta acaatgggat ctttggcttt tgtaccaaac gcgtattggc ttttgatcat
     3061 gcggttttgg aatgggattt tgtctggata tattccaaat gccacagcga tgattgcttc
     3121 acaggcacct agagaaaaga gcggatgggc gttaggaaca ttgtctaccg gagcgattgc
     3181 tggaaatctg atcggacctt caatgggcgg tgcactggct cagtggtttg gtatggaaaa
     3241 tgtattcttg atcacagggg ctttgttgat gatcacaacg gtattgacca ttttcttagt
     3301 caaagaagat ttccatccaa tcgagaaaaa agatctgata agcaccaaag aaattttttc
     3361 aaaaatggat catctctcta ttttgatcgg tctcttcatt acgaccttga ttttacagat
     3421 aggaatcact acgatcagcc ctattttgac cttatatatt cgtgaattga gcggaagtac
     3481 agaaaatatc ctttttgtca gcggcttgat tgtttcgata gctggtgttt ccgctgtctt
     3541 ttcttcaccg aaactaggaa aactagggga taagattggg aatcaaaaag ttctaattgg
     3601 aggactcatt ttatcatttt gctgttattt acctatggca ttcgtcacta caccgctcca
     3661 attaggtata cttcgcttta ttttaggctt ttcaactggc gctttgatgc cttctgtcaa
     3721 tacactgatc agtaagatta cgcctcaaga aggagtcagc cgaatctata gctacaatca
     3781 gatgtttagc aactttggac aagttttagg tcccatgcta ggatcgacag tcgcgcatgc
     3841 ttataattac agtgctgttt ttattgtgac aagtttgttt gttctgtcaa atattcttct
     3901 ttctttattc aactttcgta aagttcttcg cagcagatta taatggtggt gaggagtaga
     3961 aaataaaaaa gagcttgaga aatctcaagc tcttggctgt ttttttacga atgggcagag
     4021 gtttcttttc ttggcgcaac tgcaccaatc aaaaggataa tgacacccgc aatgaatgaa
     4081 atgattgttg tcaaagtaaa atcatatgtt ccgcttgtta atgcagcacc aatataaccg
     4141 actacttgac ctagaacgac agcccagaat aatgtaacga tatatcgcat aaagaacacc
     4201 tcttttctat cttaatttta ccagattttc tttgaatgta aagaaacgag accaaatctc
     4261 aataaaattt gagttcttgc gaaagaactc attcctacag attacaagca agcaaatgaa
     4321 gtggaataat caacttcagc gcctgctatc ttaatgaaag taaaaggatc aaacctttta
     4381 acgctagtga attttaacga aaaaaaaggc ggaatgcaag atgtttttcc cacaacttta
     4441 tacaattact tcttattctc ttttacaaag tacgatacgt attcgagaat atgtacaaga
     4501 agcaaaaaaa caaggctaca cttcattagc cataacggat aaagatgtct tatacggtgc
     4561 acctgaattc tatcgtattt gtgtagaaga aggagtacag ccaatcattg gattacatct
     4621 tagttatact tatgaagaaa aaaattatgg cttgcttgcg tacgcaaaag atgaaatagg
     4681 ttatcagcag ctgatgaaac tttccagccg aaaaatgatc caagaaaaat tggaacttgc
     4741 agaaatgaca gaaaccgacc atctagcgtt tgttgttccg gcaaatcatt ctgtttctga
     4801 ggctttcaat aaagaggata actttttcgg tcattggcag tttttacttg aaaatgtttt
     4861 tactagaaat ttttatatcg gcttgacaga aaacacgcct gatcaattgc ctgaatggta
     4921 tcagtatgtg ataaaagaaa attattcgct ttgtgcatta catcccatcg ctagtttaca
     4981 acaagaagaa ctttttgcac ttgaagtgat gaaacatatc aaagagggaa gccaaatacc
     5041 tttagaaaat ttatctgcat ctttaccact aacagcaaat gtctatcttc tttcagaaca
     5101 agaaatgatc aaacgattcg aaaaagcggg tctttcccaa gctgtaatag gcgcccagcg
     5161 tttagctgaa tcgatttcat ttgaattcca gttccatcag aaattacttc cgcattatcc
     5221 agttcctaat ggaaaacaag ctggagaata tttaagagag ttatgctatt cgcaagtgga
     5281 acgccgaatc actgactata caaaggaata ccaagaacgt ttggactacg agttatctgt
     5341 catccatcaa atgggattcg atgattattt cttgatcgta tgggatgtaa tggcttttgc
     5401 tcatagaaac aaaatcgtta ccggtgcagg tcgtggttct gctgcgggtt cattagtagc
     5461 ctatgtgtta gaaatcacag atgtggatcc attagaatat gatttgctgt tcgaacgctt
     5521 tttaaacccc gaacgcttta cgatgccaga tatcgatttg gatattcctg acaatcgacg
     5581 tgaagaagta ttgaattatg ttcgagaaaa gtatggacaa tatcatatgg cacaaatcgc
     5641 aacatttggc acaatggcag caaaaatggt tcttagagat gcagctagag tgtttggttt
     5701 atcgcaaagt gaagcaaacc gctggtcaaa agcaataccc aatcaattga aaatcacatt
     5761 gacccaagct tataaaactt cgcatcaatt agtagaatta gttcaggcaa gcgaaaaaaa
     5821 ccaactttta ttcaaaactg cagtgatttt agaaggattg ccaagacatg tttcgactca
     5881 cgcagcaggt gtagttatca gcgataagaa tctacttgaa ctagttccgc tccaacgcgg
     5941 ttctgatgaa gcttttctga cccagtatac gatgaatgag gtagaagcaa tcggtctttt
     6001 gaaaatggac tttttaggac tacgcaactt atcgattatt gattttactt tgaaagctgt
     6061 taagcgagta gaagggtatg agatccgatt aaaagagatc ccgctaaatg atgcaaaaac
     6121 gctgctcttg tttcaacgag gcgaaacctc aggagtattt caatttgaat ctgctggtat
     6181 ccggaacgtt ttacgaagat tagatccaga aaacatcgaa gatattgccg cagtcaatgc
     6241 attgtatcga ccaggcccta tgcaaaatat agataccttc attgccagga agaaaggaaa
     6301 agaagccatt cgctacccag atgattcact gatcccgatt ttgaaaaaca catatggagt
     6361 gatcgtctat caggaacaaa tcatgcagat cgcctcgact atggctggat ttacattagg
     6421 gcagtcagat attctgcgac gggcagtgag taaaaagaaa aaagacgtat tagatgaaga
     6481 aaagtcgcat tttgtatcag gagcattaca acagggatat tcggaaaaaa cagcagcgac
     6541 cgtatatgaa tatatcgaaa aatttgcaaa ctatggattc aatcggtcac atgcatttgc
     6601 ttattcattc gtgggattcc aaatggcgta tctaaaagcc catcatccag gtgctttctt
     6661 taccagcctg atgaattctg ttcggcataa cacatcaaaa ttgaaagaat atattgcaga
     6721 agcacgtaaa aataaactca aactttcctc gccgtccatt aatcaaagta attccagttt
     6781 tgagttggtc aataaggaag aaatcagatt cggactgaca gcgataaaag gtattcggcg
     6841 tgattttgta gaagatatat taaacgaaag aaaacaaaat ggcccgttcc agtcagtgga
     6901 tcaattcctc atacggatcg ataagcgttg gctgaaatta gagttactgc aatcactgac
     6961 agcagtagga gtttttgatg aattatctcc taacaggaaa caattgatgc ttgatctcga
     7021 aggaaaaatc caaaatatcg tttacagtgg tggaagtctt gacttgctgg gaatcatggc
     7081 attaaaagaa gaagaagtcg ctgactatac actagaagaa cgcttgaagc tggaagagga
     7141 gtacttaggt atttatttgt caggtcatcc tgcagaaggg tttgatcgtc ttcgtttagc
     7201 taaacaagtt cagctgatta cagatatcgt ccctaatcaa ccagtcaatt tattagtgat
     7261 gatcaaggaa gttagagaaa ttcggacaaa aaaaggagaa ctgatggcct ttgttgaagg
     7321 aaccgacagt agtggagaaa tttctgtcac agtttttcca actctttatc gtaaatatcg
     7381 taatttgttt gccgttgatc gagtgatctt tgttcaaggg cggagcgaaa tcagcaaata
     7441 taatcaggaa ctgcaactaa ttggagaaag ctttgctgat cctaaccagt tagaagccca
     7501 gtatccttca caaacttgct atttgcgtat tacagaagaa cgggaagatc ccgagataat
     7561 gaaacaatta caagtgattt ttcagaaaca cccaggatat ataccagtag ttatgtatca
     7621 cgaaaaaacg caacgaaaag tagttctgtc agatgcttat tgggtggatg acagcaagag
     7681 tataaagcgg caacttattt atctgcttgg cgaagataat gtggttttca aataacttac
     7741 ggtaaaaaat actacttgct ttcatttttt ttcatttttt tatccgtaaa tcaagacaag
     7801 tgagaaaaat aatgttagaa tgttagtcgt ggttaacgca aaaatggttg taaacctaag
     7861 tcatacttag gataaagtat tttaatgagg tgaatgttta ttatgaaacg catcggaatt
     7921 ttgaccagtg gcggagacgc acctggaatg aatgcagctg ttcgtgccgt tgttcgtaaa
     7981 ggtatttacg aaggactgga agtatacggg atcaattatg gttttgccgg tttagttgct
     8041 ggagatattc gtcgtcttga tgtggcagat gtaggtgaca agatccaacg tggtggtaca
     8101 ttcttgtatt ctgcacgtta tccagaattt gcaactgaag aaggtcaatt aaaaggaatc
     8161 gaacaattga aaaaattcgg aatcgaaggt ctagtggtta tcggaggaga cggctcttat
     8221 catggcgcaa tggctttgac aaaacgcggt ttcccagcag taggtattcc tggaacaatc
     8281 gataatgata ttcctgggac tgatttcaca atcggttttg atacagcaat caatacagta
     8341 ctagaatcaa ttgaccgtat tcgtgacaca gcgacttctc atgttcgtac attcgttatc
     8401 gaagtaatgg gacgcaatgc aggagacatc gctttatggt caggtgtggc tggcggagcg
     8461 gatgaaatca tcatcccaga acatgatttt gatatggctt cagttgctaa aaaaatccaa
     8521 gaaggccgcg atcgcgggaa gaaacattgc ttgatcatct tggctgaagg tgtaatgggc
     8581 ggaaatgaat tcgctgagaa actttcagaa tttggtgact atcatacacg tgtatctatc
     8641 ttgggacacg ttgtccgtgg tggagcacca agcgcacgcg accgcgtgtt ggcaagtaaa
     8701 ttcggtgctt acgctgtcga attgcttcaa gaaggaaaag gtggattatg tgtcggtatc
     8761 catgacaacg aaatcgttgc gtctgacatc attgatacac ttgaaaacaa caaacataaa
     8821 ccagacttat cactatatga tctaaataat tcactttcat tttaagagtg aaagaaacca
     8881 agctatttaa gctgtgtaca gctttaaata aacaaaattg aatgggagag ttttttaaat
     8941 gaaaaaaacc aaaatcgtta gtacattagg accagcaagt aactcagtag aaattatttc
     9001 tcaattgatt gaatctgggg caaatgtctt ccgctttaat ttttctcatg gtgaccatga
     9061 agaacaatta tcacgtatga ctatggtccg tgaagcagtt aaaaagacag gaaaagatgt
     9121 cggtattctt ttagatacaa aaggagctga aatccgtaca actgttcaag gcacaacaga
     9181 agctgatttt ggtcgtgcag gatacatcaa atttgaagta ggagatcaaa cacgcatctc
     9241 tatggatcct gaacatgtag gttcaaaaga aaaaatcgcg gttacttacc caggattatt
     9301 tgacgatgtt cacgttggcg gacacatttt atttgatgat ggtttgatcg atatgcaaat
     9361 cattgaaaaa gacgaagcaa accgtgaatt agtcgtagaa gttaaaaatg caggtatgct
     9421 aggatcacgt aaaggggtaa atgcaccagg cgtttctatt agtttgccag gtattactcc
     9481 aaaagatgct gacgatattc gttttggttt agacaacgat atcgacttta ttgctgcaag
     9541 ttttgtacgt aaagcacaag acgttctaga tatccgcgaa atcttagaag aaaaagacat
     9601 gactcatgtt caaatcttcc ctaaaatcga atctcaagaa ggtatcgaca acattgacga
     9661 aatcatcaaa gtttctgacg gtgttatgat tgcccgcgga gatatgggtg ttgaaatccc
     9721 agctgaacta gtaccaatgg ttcaaaaacg cattatcaaa aaatgtaatg ctgctggtat
     9781 cccagttatc actgctacac aaatgttaga atcaatgcaa gaaaacccac gtccaacacg
     9841 tgcggaagct tctgacgttg ctaacgctgt atttgatggc acagatgcaa caatgctatc
     9901 tggtgaatct gcaaacgggg actacccagt tgaagctgtt tcaacaatgg cacgtatcga
     9961 ccaagaagct gaaaatgcat tatcagaatt aggtacattc caattgaacg aattcgataa
    10021 aacagatgta actgaaacaa tcggtttatc tgtagctcgt gctgcaaaaa atctaggcgt
    10081 gaaaacaatc gttgctgcaa ctgaatcagg atacactgca aaaatgattt caaaatatcg
    10141 tccagatgca gatatcttgg ctgttacttt tgacgaacgc acaaaacgtg gtttgatgtt
    10201 aaactggggc gtttacccaa cagttgctga aaaaccatca acaactgatg aaatgtttga
    10261 actagcagct aaaaaagctg ttgaattagg tttcgcatca gaaggcgatt taatcttgat
    10321 cactgctggt gtaccagttg gtgaacgcgg aacaactaac gtgatgaaaa ttcaaatgat
    10381 tggttctaaa ttattagaag ctcaaggcgt tggacaaaaa tctgtcgttg caaatgcagt
    10441 tattgcttca tctgctgaag aagctgtaaa aaaagcaaaa gacggaatgg ttctagttgt
    10501 accatcaact gacaaagaat atatgcctgc aatcgaaaaa gcagctgctg ttatcgttga
    10561 agaaggcgga ttgacttctc acgctgcagt tgtaggaatt gcacaagata ttcctgtaat
    10621 cgttggtgct aaaggcgcaa caacaacaat tacagaaggt gaattgatta ccgttgattc
    10681 acgtcgcggc atcgtttacc gtggcgaaac aacagctatc taatttagct taataaaaaa
    10741 taaaaacagc tcttctttta cgaagagctg tttttttgtg ctgtaacgaa ttcatggata
    10801 acttggacta cttgttcttg aagaggcgtg acgatctgct gtgttcgttt tgccaatgaa
    10861 atcaagaagc gaggctgaac ttcatctgaa agagggaggc aaactaaatg atcttcagga
    10921 tggacagcaa tctctgccaa aaaaccgata cccacatttt ctcggaccat actctttaaa
    10981 atcgtcaagt cattgctttg ataaacaact tttggatgag tatgtgtttg tttagaaagc
    11041 ttagtgaatg ctgcggggtg gacataatgt tcgttcaata gtacaaactg ttcatctgct
    11101 atatctttga aagagacagt atcctgcttg gaaagaggat gtgtaggtgg cacgacgatc
    11161 atgaaacgtt tgtccaaaag taactctgtt tctaaatatt gatccacgat tggctgtgtt
    11221 gagcctaata cagctaaatc gatcctccct tgtcggatca tcccgtataa gtcccgagag
    11281 cctccatcgg taatctcaat ttgattcatc aattcatgct tgataaagta acttgacagt
    11341 ttaggaaagt attcattgcc gataatagga ggcatgccaa aacgaagctt tttcttttgc
    11401 aactgagtga tttcagctct tgcagtagaa atctcttgga gaatggtttg tgcatggaga
    11461 aacagctgct ttccagaagg cgtgacgatt aattcgtgat gcgatcgatc tcttgtaata
    11521 agtacggtgt caaactcttt ttcaagacgt tgtaatgcat atgtaatagt aggttggctc
    11581 acacggaaat aattagccac tttcgtaaaa tttttttgtt tgacgatttg gacatagtat
    11641 tcgatatctt tcgtgttcat gaagatcatc cgctccttta atggaataat gattattgta
    11701 aatgattctg aggatgatag caaacagagg ctttctaata aagatttttc tgttttttta
    11761 tgaactgcaa ggtgtcaaga aaatttcatt gacaacatgc tttttgccct gtataattgc
    11821 ttttgttgct taggagtgat gaaaaatgaa atggtcttta ttggaattga gaaaatacca
    11881 ggagacaccg ttaacttttc atgagacgct cgacttgaaa gccgctctca tgaagcgaga
    11941 caatttaata cttgatgttg cgccagtgga agtcgaaggt ttggtctcag ttgataagaa
    12001 aggctatatc gttcattaca ctgtgcagac gactttgaca gttccttcaa cacgttcact
    12061 agaacctgtt gaactgccca tggatttttc tgtagacgaa gtattcatga cagaagaaca
    12121 attccaaagt agagatgaac aaatgtctgc ggatgagatt ttgctaattg aaggtccatt
    12181 attgaattta gcagagtcga ttgaagacaa catcttattg gcgattccaa tgcgggtatt
    12241 gacaaaagaa gaggaagcag caacagaact tccaaaaggc aatgattggg aagttgtttc
    12301 cgaagaagaa taccagcgca gaaaaatgga agaagccgag aataaaattg atcctcgtct
    12361 tgcaaaacta tctgaacttt ttgattctaa atcaaaagac gacgataaca agtaagattg
    12421 gaatatattg tgtctaattt agatacaaga ctttacaagg aggtgtagca aaatggcagt
    12481 accagctaga agaacatcaa aagctaaaaa agcaaaacgt cgtacacact acaaattgac
    12541 aatcaaaggg ttaaacgaat gtccaaactg tggtgaaatg aaaaaaagcc atcacgtatg
    12601 tgcaaattgt ggttactatg atggtaagga cgtaatgtca aaagaagctt aatacatttt
    12661 aattagaaaa tgtaaaacct caaggctaac catggagcct tgaggtttat ttttttgtag
    12721 tcggtaaata aaaaatatgt tgttctttag tttgcaatgt agccgtgtta agctataatg
    12781 taagagatta gggagaaatc ccgtatgtag gaggagttca tatgtcaaaa caacaaatcg
    12841 gcgttgtcgg tatggccgtt atgggtaaaa atctagcctt gaacatagaa agccgcggct
    12901 attcagtggc tttattcaat cgtacagggg ctaaaacaac cgctgtagta gaagaacacc
    12961 cagataaaaa tttcaaagca acatatacaa tcgaagaatt tgtagaatct atcgagaaac
    13021 cacgtcggat cttgctaatg gtcaaagcag gaccggcaac agatgcaacg atccaagagt
    13081 tgcttcctca ccttgataaa ggcgatattt tgattgacgg aggaaataca ttctttaaag
    13141 atacgatgcg tcgtaatgaa gagttagcca actctggcat caactttatc ggtacaggcg
    13201 tttccggtgg tgaagaagga gctttaaaag gaccttcaat catgcctggt ggacaaaaag
    13261 aagcctatgc gctagttgca ccaatcttag agcaaatttc tgcaaaagca gaagacgaag
    13321 caccatgtgt cacatatatt ggcccaaatg gagccggaca ttatgtgaaa atggtacaca
    13381 acggtattga gtatggagat atgcaactga ttgctgaatc ttatgactta atgaagaata
    13441 ttttaaacct ttcagtagaa gaaatggctg atatctttaa agaatggaat caaggcgaat
    13501 tagacagcta tttgatagaa atcactgctg acattctgac acgtaaagac gatgaaggaa
    13561 caggtaaacc agtagtagat gtgatccttg atgcagctgg gaataaagga acaggtaaat
    13621 ggacaagcca aagcgcgctt gacttaggtg tgccacttcc attgatcact gaatctgtat
    13681 ttgcccgcta tatttctgct tataaagaag aacgcgtaca agcaagcaag attttatctc
    13741 gtacgaacga ttttgagttc acgggagaca aaaaagaatt ggtcgaaaaa atccgagaag
    13801 cgttgtattt cagtaaaatc atgagttatg cccaaggatt tgctcaatta cgtgtcgctt
    13861 caaaagaatt tgattgggac ttgccatttg gtgaaatcgc aaaaatctgg cgcgctggat
    13921 gtatcatccg agctcgattc ttgcaaaaaa ttacggatgc ctatgacaaa aatcctgaga
    13981 tcgaaaattt attgctagat gattacttcg ttgaaatcac gaaaaaatat cagcaatcag
    14041 tcagagacgt cgttgccttg gctgtccaag ctggcgtacc tgtaccgact ttctcatcag
    14101 ccatcgctta cttcgattca tacagagcag aacgtctgcc tgcaaatata atccaagccc
    14161 aacgcgatta ctttggcgca catacctatg aacgtgtcga caaagaagga atcttccatt
    14221 actcatggta ccatgaagaa taatagtctt tcggctgtta ggaaatgaga aaataaaaag
    14281 aggacgaaag agctgaagtc gattgttatg agtagacttc agctcttttt taaaattgct
    14341 atccatgata aaatgactat agatttttaa gcatattatc ggtataatga tagagttttt
    14401 aaaaagccag tagaatagaa aggataaaat aataaatgag caatattcta atcattgaag
    14461 atgaaaagaa cttggcacga tttgtcgagc tagagttgaa gcatgaaggg tataacgcag
    14521 aagtccacta caacggccga actggtttag atgcggcatt aaataatgag tgggatgcca
    14581 tattgttgga tctgatgctc ccagaattga acggtttaga agtctgcaga cgtgtacgcc
    14641 aagtcaaaaa tacaccaatc attatgatga ctgcaagaga ttctgtgatc gatcgtgtat
    14701 ctggacttga ccacggagca gatgactaca tcgtcaaacc atttgctatc gaagaattat
    14761 tagcacgtct tcgtgcattg ttgcgtcgaa tcgatattga aggcgataaa aatgtggcta
    14821 aacaaactac tattacttat cgcgatttga ctatcgaaaa agaaaaccgt gtcgtacgtc
    14881 gcggaaatga agtaattgaa ctaacaaaaa gagaatacga gttgctgctt actttaatgg
    14941 aaaacgtgaa cgtggtatta gcacgtgacg ttttactaaa taaagtgtgg ggatacgaaa
    15001 cagaagttga aacaaacgta gtggacgtat atattcgtta tcttcgcaac aaaattgacg
    15061 ttcccgggga ggaaagctat atccaaactg tacgcggaac aggttatgtg atgcgctcgt
    15121 gataaagccg aaaaaatcgg aaaaaagaga actgaaaggg ccctccttga caatcaagtg
    15181 ggcctttgcg agttctttct tcatattcgt tgtgtttaca attttcgctg tcattaccta
    15241 taaatcatct atcaatctga ttgtggcaaa agaaagaaac aatgtagagc gtacgatttc
    15301 agaagtagct tctcgtttgg ctaactcgga tgaagaactg acattagtaa atacgtatcg
    15361 taatctgacg aaagcgacaa atgacggaga tgaggtcgta gatcatactt cactggtcga
    15421 aggaaactta atgaagatcg attcctttat agctgagcta gggcagccat caatggatct
    15481 ttatgtttat gatttggacg agaacttgat ttttaaaacc catgaaaaca gtcgaaacct
    15541 gattcagact acacgtaaag ttccaacgat cgttacacta gaaggaaaaa ctggcttttt
    15601 atctatccag cctatatatt ctaaaggtac aagagaaaag atcggctatg cgcaaagctt
    15661 ctatgaatta tcttctttct atgatattcg aaataagcta ttattgactc ttattgtttt
    15721 agaagttgtt tctttgatct taagtagtat tttaggtttc tttttatctt cttatttctt
    15781 aaaaccactc aaggtactca gagatacaat ggatactata cgtaaagatc cgcaatcaga
    15841 tatccacatg cctgaaatcg acacaaatga tgaattggca gatttagctg aaatattcaa
    15901 tgagatgctt gaccgtatgc gtttgtatat tgaacaacaa gagcaattcg tggaagacgt
    15961 atctcatgag ttaaggacac ctgttgcaat tattgaaggg catcttagtc tgctaaatcg
    16021 ttgggggaaa gatgatcctg agatattaga agaatcatta agcgccagca tgcaagaaat
    16081 tagccgtatg aaaagcttag ttcaagagat gctagactta tcaagagcag aacaagtaga
    16141 tgttcattat gcgaatgaaa caactaaagg aaaagaagtc acctatcaag tttataataa
    16201 tttcaagata ttatatccag actatgtgat cactttagat gatgatttga caaaagaagt
    16261 gaccctgcaa atttatcgta atcactttga acaattaatc attatcatat tggataacgc
    16321 agtaaagtat tcaactacac gaaaagaagt ccatatctct atttcttcca ctctgaatga
    16381 atttgagatc gcgattcagg actttggcga aggaataccc aaagaagacc ttaataagat
    16441 cttcaatcgt ttttatcgag tggataaagc aagagctaga acgaagggtg gaaatggtct
    16501 ggggttgtct atcgctaaac aactggttga aaactataaa ggacgtatct tagcagaaag
    16561 tgtagtaggg caagggacaa tttttagaat ctttattcct atcgcaaagg cagaagacaa
    16621 gtaaagcatg tgctttactt gtttttttat atatccaaca aagaataagg tacaaaatac
    16681 aagcaagtta gaaattcagg aatgtcatta taaaaaaaac tagcgaacaa ttaaatagaa
    16741 taacatccgt taattaaacg taagtagctt ttagatgaac gaaaaaacaa tgaaatgctg
    16801 taatattcgt gtttaaaaat aataaataaa aatagggaat tttctattgc aattttataa
    16861 agagattgct atattattat ttgttctaaa tgattccttt aaggtgtcac taaaaattat
    16921 aaaaaatagg gttgacgcac ttttgatgtc atgttataat aacgaagtcg tttggatgag
    16981 gtagctaata aagcttgatt ttatcgaaaa aaacttcgaa aaagttgttg acaaataaca
    17041 ataaagatga tatgataatc aagtcgctgc taatgagtga caaagacgtt tagaaaaaat
    17101 aaacaaagaa gttgttgaca ttctcttctg aatctgataa gattaaagag ttgttgaaac
    17161 aaaaaga
//
LOCUS       DAZKNV010000055        16573 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000055 DAZKNV010000000
VERSION     DAZKNV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.055"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(24..722)
                     /locus_tag="ACG8M1_002112"
     CDS             complement(24..722)
                     /locus_tag="ACG8M1_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFQ0422789.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="ACG8M1_002113"
     CDS             complement(715..2067)
                     /locus_tag="ACG8M1_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFQ0422790.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="ACG8M1_002114"
     CDS             complement(2290..3690)
                     /locus_tag="ACG8M1_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFQ0422791.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="ACG8M1_002115"
     CDS             3851..4588
                     /locus_tag="ACG8M1_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFQ0422792.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="ACG8M1_002116"
     CDS             4713..5192
                     /locus_tag="ACG8M1_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFQ0422793.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="ACG8M1_002117"
     CDS             5189..5956
                     /locus_tag="ACG8M1_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFQ0422794.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="ACG8M1_002118"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="ACG8M1_002118"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0422795.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="ACG8M1_002119"
     CDS             complement(6859..7461)
                     /locus_tag="ACG8M1_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFQ0422796.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..7797
                     /locus_tag="ACG8M1_002120"
     CDS             7567..7797
                     /locus_tag="ACG8M1_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422797.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7788..8036
                     /locus_tag="ACG8M1_002121"
     CDS             7788..8036
                     /locus_tag="ACG8M1_002121"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422798.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8142..8726
                     /locus_tag="ACG8M1_002122"
     CDS             8142..8726
                     /locus_tag="ACG8M1_002122"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFQ0422799.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="ACG8M1_002123"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="ACG8M1_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFQ0422800.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="ACG8M1_002124"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="ACG8M1_002124"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFQ0422801.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="ACG8M1_002125"
     CDS             10627..10806
                     /locus_tag="ACG8M1_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422802.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="ACG8M1_002126"
     CDS             10828..11853
                     /locus_tag="ACG8M1_002126"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFQ0422803.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12028..13272
                     /gene="glyA"
                     /locus_tag="ACG8M1_002127"
     CDS             12028..13272
                     /gene="glyA"
                     /locus_tag="ACG8M1_002127"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFQ0422804.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13425..14372
                     /locus_tag="ACG8M1_002128"
     CDS             13425..14372
                     /locus_tag="ACG8M1_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFQ0422805.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14506..15135
                     /gene="upp"
                     /locus_tag="ACG8M1_002129"
     CDS             14506..15135
                     /gene="upp"
                     /locus_tag="ACG8M1_002129"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFQ0422806.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15274..15516)
                     /locus_tag="ACG8M1_002130"
     CDS             complement(15274..15516)
                     /locus_tag="ACG8M1_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422807.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15637..15709
                     /locus_tag="ACG8M1_002131"
     tRNA            15637..15709
                     /locus_tag="ACG8M1_002131"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15670..15672,aa:Thr,seq:cgt)
     gene            complement(15828..16466)
                     /locus_tag="ACG8M1_002132"
     CDS             complement(15828..16466)
                     /locus_tag="ACG8M1_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFQ0422808.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT         5651 a         2952 c         3330 g         4640 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt
    12061 tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct
    12121 gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac
    12181 gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa
    12241 aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct
    12301 cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg
    12361 atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc
    12421 agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat
    12481 tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc
    12541 agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc
    12601 gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct
    12661 aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct
    12721 cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta
    12781 tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc
    12841 aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa
    12901 gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat
    12961 aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc
    13021 attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt
    13081 ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa
    13141 gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat
    13201 aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg
    13261 cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc
    13321 tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga
    13381 ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct
    13441 cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg
    13501 aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca
    13561 aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata
    13621 ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg
    13681 gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg
    13741 ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc
    13801 caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa
    13861 aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta
    13921 cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt
    13981 attatccagt cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact
    14041 attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag
    14101 agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc
    14161 cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg
    14221 cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc
    14281 atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat
    14341 tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt
    14401 ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg
    14461 ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa
    14521 gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga
    14581 acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca
    14641 cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa
    14701 acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt
    14761 gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat
    14821 gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt
    14881 cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat
    14941 gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag
    15001 ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat
    15061 gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg
    15121 tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt
    15181 ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa
    15241 aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt
    15301 aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat
    15361 ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg
    15421 aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat
    15481 agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta
    15541 taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa
    15601 tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca gttggtagag
    15661 caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa
    15721 gacagatata tcaaggattt ttaatccatt gatacatctg tctttttgtt taaaggaaat
    15781 aaagtatgct ttcttagcaa tagagcatgt attatttcta taaaaattta ggagaataaa
    15841 acgactagca atatagctgt gaaatcaaat atcacatgaa ctgcccaact tgtaatgatc
    15901 gagttgcttt taatggcagc ttggttgaat aacaatcttg ccaccccttg tatcaaaagg
    15961 atgtgtgcta cagtgtgtaa aatatttcca ttatcataag tactgtaatg gataaatcca
    16021 aagatgattg ctgacaagaa actagcgaca ggaatgctga acttactaga aaaaatagcg
    16081 agaaaataca ctgagaacaa ttcttctcca agtatcatga taggcaaaat aataaataat
    16141 aacgggctga aagcctcatt tattggattg cctgttaaac cccatttcaa aatttgttgc
    16201 aaaaataccg agactgcggc actgattact acattgataa aaaaatattt ggctatattt
    16261 ttgacaggag cgacaggttt cgagaacatt tttttcgtat cttttttacc aaaaacaagt
    16321 gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc taataatgga tggcgcaaat
    16381 agcaacccta acaaaccgag tacaacgaca atagtgccca atatcccttt tttaagttct
    16441 attttttttc ctaaaatgtt attcatgata ataactccta ctattcagtt tttgaagata
    16501 gagtcagtat acatgaagag ttaaaatagg caatgttttt ttatggatat ttgtattgct
    16561 aaaaatttat ctt
//
LOCUS       DAZKNV010000056        16153 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000056 DAZKNV010000000
VERSION     DAZKNV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.056"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            226..894
                     /locus_tag="ACG8M1_002133"
     CDS             226..894
                     /locus_tag="ACG8M1_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFQ0422809.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1414)
                     /locus_tag="ACG8M1_002134"
     CDS             complement(1094..1414)
                     /locus_tag="ACG8M1_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422810.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(1451..2833)
                     /locus_tag="ACG8M1_002135"
     CDS             complement(1451..2833)
                     /locus_tag="ACG8M1_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFQ0422811.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="ACG8M1_002136"
     CDS             complement(2989..4176)
                     /locus_tag="ACG8M1_002136"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFQ0422812.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="ACG8M1_002137"
     CDS             complement(4183..5214)
                     /locus_tag="ACG8M1_002137"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0422813.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5230..6684)
                     /locus_tag="ACG8M1_002138"
     CDS             complement(5230..6684)
                     /locus_tag="ACG8M1_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFQ0422814.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            6859..7764
                     /locus_tag="ACG8M1_002139"
     CDS             6859..7764
                     /locus_tag="ACG8M1_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFQ0422815.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="ACG8M1_002140"
     CDS             7855..8532
                     /locus_tag="ACG8M1_002140"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFQ0422816.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8529..8699
                     /locus_tag="ACG8M1_002141"
     CDS             8529..8699
                     /locus_tag="ACG8M1_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422817.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8813..9709
                     /locus_tag="ACG8M1_002142"
     CDS             8813..9709
                     /locus_tag="ACG8M1_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0422818.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="ACG8M1_002143"
     CDS             complement(9764..11134)
                     /locus_tag="ACG8M1_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0422819.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="ACG8M1_002144"
     CDS             11372..12118
                     /locus_tag="ACG8M1_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0422820.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="ACG8M1_002145"
     CDS             12115..12954
                     /locus_tag="ACG8M1_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0422821.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="ACG8M1_002146"
     CDS             12955..13905
                     /locus_tag="ACG8M1_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422822.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="ACG8M1_002147"
     CDS             14046..14798
                     /locus_tag="ACG8M1_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422823.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="ACG8M1_002148"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="ACG8M1_002148"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFQ0422824.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5243 a         3011 c         3241 g         4658 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgctag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt tcatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctacattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattcaa agtttttgtc cagtaattgt tgtaacaatt
    16021 actggttttt ttgtattttt tacatttttt taagagaatt tgataaaaat caaaaatttt
    16081 tttgcttttt tttatggatt attgcagtga atgttacaga atctgcgttt ttcattcaaa
    16141 aataaaaaaa cat
//
LOCUS       DAZKNV010000057        15953 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000057 DAZKNV010000000
VERSION     DAZKNV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.057"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            15..533
                     /locus_tag="ACG8M1_002149"
     CDS             15..533
                     /locus_tag="ACG8M1_002149"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0422825.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            661..1344
                     /locus_tag="ACG8M1_002150"
     CDS             661..1344
                     /locus_tag="ACG8M1_002150"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFQ0422826.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1653..1726
                     /locus_tag="ACG8M1_002151"
     tRNA            1653..1726
                     /locus_tag="ACG8M1_002151"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Arg,seq:tct)
     gene            1885..2244
                     /locus_tag="ACG8M1_002152"
     CDS             1885..2244
                     /locus_tag="ACG8M1_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFQ0422827.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2367..3998
                     /locus_tag="ACG8M1_002153"
     CDS             2367..3998
                     /locus_tag="ACG8M1_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFQ0422828.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4060..4701)
                     /locus_tag="ACG8M1_002154"
     CDS             complement(4060..4701)
                     /locus_tag="ACG8M1_002154"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFQ0422829.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4887..4963
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4983..5291
                     /gene="rplU"
                     /locus_tag="ACG8M1_002155"
     CDS             4983..5291
                     /gene="rplU"
                     /locus_tag="ACG8M1_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFQ0422830.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5318..5662
                     /locus_tag="ACG8M1_002156"
     CDS             5318..5662
                     /locus_tag="ACG8M1_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFQ0422831.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5675..5968
                     /gene="rpmA"
                     /locus_tag="ACG8M1_002157"
     CDS             5675..5968
                     /gene="rpmA"
                     /locus_tag="ACG8M1_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFQ0422832.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6402..9209
                     /locus_tag="ACG8M1_002158"
     CDS             6402..9209
                     /locus_tag="ACG8M1_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0422833.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9400..9891
                     /locus_tag="ACG8M1_002159"
     CDS             9400..9891
                     /locus_tag="ACG8M1_002159"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFQ0422834.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            9994..10983
                     /locus_tag="ACG8M1_002160"
     CDS             9994..10983
                     /locus_tag="ACG8M1_002160"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFQ0422835.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11016..11819
                     /locus_tag="ACG8M1_002161"
     CDS             11016..11819
                     /locus_tag="ACG8M1_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFQ0422836.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11840..12754
                     /locus_tag="ACG8M1_002162"
     CDS             11840..12754
                     /locus_tag="ACG8M1_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0422837.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12837..13211
                     /locus_tag="ACG8M1_002163"
     CDS             12837..13211
                     /locus_tag="ACG8M1_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFQ0422838.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13350..13595
                     /locus_tag="ACG8M1_002164"
     CDS             13350..13595
                     /locus_tag="ACG8M1_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0422839.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13767..14831
                     /locus_tag="ACG8M1_002165"
     CDS             13767..14831
                     /locus_tag="ACG8M1_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFQ0422840.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15077..15502
                     /locus_tag="ACG8M1_002166"
     CDS             15077..15502
                     /locus_tag="ACG8M1_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0422841.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15495..15944
                     /gene="nusB"
                     /locus_tag="ACG8M1_002167"
     CDS             15495..15944
                     /gene="nusB"
                     /locus_tag="ACG8M1_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFQ0422842.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
BASE COUNT         5103 a         2642 c         3484 g         4724 t
ORIGIN      
        1 agaagttgaa aacgatacct gattacaaaa aaataacttt tataagttct ataacgttga
       61 ttatattttt aattcttatt cttctcgtcg tcttggttcc ccgaattttt ggtttgactc
      121 cttatattat tgaggacaaa gaaatgagtc catattatgc acaaggaaat ctgatatatg
      181 tacgaccgaa aaatacaaat gagattttag tcggagatat tattacatat tatgaaaatt
      241 caggaaaaaa aatctcgacg cgtcgcgtaa tagccgttga aaacaaccac gaagattttt
      301 atacaaaagc tgatacaaag acttatattg agcctggagt agtaaaaaag agaaatatta
      361 tcggtagtcc catctttcag attccatata ttggactagt cctttcaaaa acggcatttg
      421 catggattca ggggttattc tttacgattg ctttttgcct aacaggaatc acagcatgga
      481 atacctttgt agagttgaaa aagaagcgga gacgaacaca gaaatttttg taagaatgtt
      541 aaaaacataa atgtattcca gagatccaac gactcttctg aacatgaaac acgagaaaac
      601 actcatgcag cttgtagatt tagtcagttg ttcgtataat gtgtgaagag gaggagtagt
      661 atgcgcaatg aaatgatgca tcgtcctgta gtcaaagaag aactattgga ttttatgcgt
      721 acccagcaaa aaaaattacc gggtgagcta ggcaaactgg aagaagaagc tcatgtagca
      781 gaagtaccag ttattcccca tgaaacagtt gtatttttga aatttttact tggacagctt
      841 cagcctgaac gaatcttgga gatcggagca gctatcggtt tttcatcaag tgtcatggcc
      901 acgacaatcg gagaaaacgc tcatgttacg acaattgatc gtttcgatgt catgatcgag
      961 aaagctaaaa aaaactatga acgtctagga ctgacagata aagtgacttt gcttgaaggt
     1021 caagcagcag atatcttgcc ggagttgtct ggtccgtatg actttatttt tatggatagt
     1081 gcaaaatcaa aatatattga atttttacct gaatgcttac gtttgttaag aaaaggtggc
     1141 gttttgatgg tagatgacat cttccaagga ggaacgatct tgctcccaga tgaagagatt
     1201 ccccgtggca aacgagctat ccatcgtaaa ttaaatgaat ttcttcgtgt tgtgatggat
     1261 catcccgatt tgacatcgac aatcttgcca ttaggtgatg gtgtgatctt aatgacaaag
     1321 gaatcagaaa caatcgagtt gtgatacatg attatggcag cctgtagata atcgattgaa
     1381 tcgagggctc aattcgaact tgatgtaaaa gtttctatat ttgtaagtca attaaaggat
     1441 acaggaaatc taaataaaca ggagtagcat gaagtcaatg tagctcctgt tttcaattga
     1501 taaccttaga acagctgaag gagaatgtct cgttttaaaa gattgattta gtagttgggc
     1561 caaaataatt cattatttgc taattaaata actatttcgt attgacagaa gcaatttaat
     1621 tatctataat tattgatgtt ccgctgattc ttgtcatagt agctcagctg gatagagcat
     1681 ccgccttcta agcggacggt cgggggttcg aatccctcct gtgacgctaa aaaaccgtta
     1741 gaaactgagg tttctaacgg tttttctttg ttttttgtgc caatattgtt tgttttcaaa
     1801 ggcaaataaa ataaaaaaac atccttatcg agtacaatta taaggagcaa aaaaataaaa
     1861 ctcatcagaa aagaggaaga agatatgacg atactatcta gaattttagt gactctagtt
     1921 gcaattgaat ttttttatat catgtatatc gaaacggtga gaactgattc tgacacgaca
     1981 agtagggttt ttaaaatgag taaagaagag ttaagcagaa aatctgttca aacattgttt
     2041 aagaaccaag gagtgtacaa tggactatta ggagtgggac tactttatgg agcttatctt
     2101 tcttccgcat ctaaagaaat cacaagtatg ctattaatat ctattttttt tgttgcatta
     2161 tatggcagtt tgactagcga tcgttggatt ttactcaaac aaggtgggct agctctgttg
     2221 gcattgcttt ctattttctt ataaatatag aaaaaataag aatttatcta acaggaaact
     2281 ttgtgaaaaa tattacttta tctcatgaaa tatgatattc taatgaatgg tattttagaa
     2341 aatttcatga aaaaggagtt agataggtgt tcaaaaatta tgtttcctca ctaaaaaaag
     2401 aattttcagg ttatgatctt tcaagatttc agaaagatct tttggctggg atcacagtag
     2461 ctgctgtagc attgccttta gccttggctt ttggggtatc aagcggagct gatgcggccg
     2521 caggtttgat tacggctatc attgccggta tcgttattgg cggtttatca ggcggttttt
     2581 atcaaatatc aggtccgaca ggtgcgatgg cagctatctt gatgtctatt gcggcaacaa
     2641 agggaatgca aggtgtattg cttgctactt ttttagcggg tctattttta cttgcagcag
     2701 gacttttccg attaggaaca ctgacttctt ttatcccagc acccgtaatt acggggttta
     2761 cttcaggtat tgctatcatt attgcattag gtcagatcga taatttattt ggtgttcact
     2821 cggaaggtac aaacgttatt gaaaaactaa gtagttatca aacgatagga tttccgataa
     2881 acacagcctc tttgatcatg ggagggctag tcattttagg gatgtttatc tatccaaaaa
     2941 aatgggcgaa acgaatgcct agttcgctgc tggctatcat tttggcaaca gcagttatgc
     3001 tattgttcca tttaccagta gcaactgtgg gtaagattcc acaaacattg atcagtagta
     3061 atcgtttgaa tatgggagat tttagctttt ctgccttgca acaagtggca gttccagcta
     3121 ttagcattgc tttattagga atgattgaaa gcttgctatg tggtgcttcg gctggccgaa
     3181 tggcaaataa gcccttagat agcaatcaag aattaatggc gcaaggaatt ggaaatctgt
     3241 tgcttccttt ctttggcggg attcctgcta ctgcggccat cgcccgtaca agcgtggcca
     3301 tcaaatctgg tgcacaaact agattagctg gtatgataca tgcagttgtc ttactgctct
     3361 ccatgcttgt ttttgcgcca gtgatgtcac agattccaat gccagcactt gcaggtgttt
     3421 tgattgtgac ggcttggcgt atgaatgaat gggaaacgat caaggagcta tttactaata
     3481 aatattggtc agcagttcta ttgtttatcc ttacgatgat ttgtacagtt atctttgatt
     3541 taagtattgc tatcgtgatc ggggtgatcg gcggctgtgt attttttgtt gtcaaaagcg
     3601 ctgctatcac gatttcatta gaaacgatcg attggcaaag aatggggctg ccagaaacgg
     3661 aaaagctgaa taactggaca gtagtgtata ttagtggtcc actgtttttt atgtcttcag
     3721 aaaaactcaa aaataaattg gaagaactaa atcatcacga tggtgtcatt ttctccatgc
     3781 gaggcgtacc aagtattgat ttgacggcac gtgcagtttt tgatgaattt caagaaaaag
     3841 cagagcaaag aggacaaacg attatctata cttccttgca gccagaagta gaaaaacaac
     3901 tttctcactt gtgggaacat acattcacgc atcaacatca aacagttgct catgcgttga
     3961 cagctttaca tgcgaaatat actgcaatta gccattaaaa caatgaaaaa gaacagacaa
     4021 gactgtaaac tgaagatttt atggtcttgt ctgttctttt taatattgct gtaaaagtga
     4081 agctagtact tgccagtctt gatggataac aggtacaagg gagcgattgt agaaaatagc
     4141 tgctggatga aaaagtggaa gaattcgata gtttttttct gaccattcgt aggcatcctt
     4201 ttgttctgtt aattgtaaga caggccctgt atagagttga ccatgatttt tggtaaccgt
     4261 atattctttg ccaagtaaac gttgaagacc aatgtttcca agtgtcgcaa ttaattttgg
     4321 ctggaccttc atcagttcgt aatccaatat tggtgcatgc gcaaatactt cggaacgagt
     4381 aggtgtccga tttggataaa cagtttctga ctgttgtgtc cgtttattga tccgatgagt
     4441 cacgcgatac gggcggctcc ttacagcact ggtgatatac acctcttctc gtgttaagcc
     4501 agttgaagaa agtgcctgca tcaattcttt tccagcttga ccgctaaaag gaacatgcgt
     4561 atcaatctct gttttccctg gggcttctcc cacgagcatc agtttaggat gaagaggtcc
     4621 ttgcccagcg ataaatcctt ctacaggacg gccgttcatt cttaaagaag cttcttgtat
     4681 cagttctttt gggtattcca tttatgctcc tcctttttct tttattataa gaataaaaga
     4741 aacacaatgc gactatttta tttggtagaa ctgtgaggat agaaaagcag aagtattgct
     4801 tgaatttttg ttttactttt tgattttaaa tttagttgac taacggttgc tgttctggta
     4861 agctagtact gttgtaattg tggactccac agctacaacc gctcagaaca agtaataagc
     4921 acagcatatg ctgtcacttc ggatggcgag tctaagtata tcagaaggag gtgctttata
     4981 gcatgtacgc aattattaaa actggtggta aacaagtaaa agttgaagtg ggacaagcaa
     5041 tctatgttga aaaacttgac gttgaagcag gagaaaaagt tgtttttgac gaagttatct
     5101 tagtaggcgg agaatctaca aaagtaggcg ctccaactgt tgcaggtgca actgttgaag
     5161 gtactgttga aaaacacggc aaacaaaaga aagtcgttac tttcaaatac aaacctaaaa
     5221 aacattcaca ccgtaaacaa ggtcatcgtc aaccatatac aaaagtggtt atcgacgcga
     5281 tcaacgctta atagcgtttg agaaagaagg cctatatatg atcaaaggaa catttaagcg
     5341 aaatgacgca ggtcagatcg tttcattcac tttgaccggg catgctgatg ctggtcctta
     5401 tggaagtgat atcgtttgtg cgggtgtttc tgcgttagcg atcagcactg tcaacgggat
     5461 tgcctcatta gccggttttg agccgattgt tgaaatgaat gaagaagaag gcggttatct
     5521 ttataccgaa gtcacttcag gaatgacaca agaacaaaac aatattgctg agattctatt
     5581 agaaaatctt ttattaggat tacaatcgat agaagctgaa aactcagaat atatccaaat
     5641 taaaacaatt aatgataaat aggaggtgca gaccatgttg ttatctatga atctacaatt
     5701 atttgcccac aaaaaaggtg gcggttctac atctaacggc cgtgactcag aatcaaaacg
     5761 tctaggtgct aaacgtgctg atggacaaac agttacaggt ggatcaattc tttaccgtca
     5821 acgcggtaca aaaatctatc caggtgtaaa cgtgggtatc ggtggagacg acactttatt
     5881 tgcaaaagtt gatggcgtag tacgtttcga acgtaaaggc cgtaacaaaa aacaagtgtc
     5941 tgtttatcca gtagctcaag aagcttaatt gaatcttatg attaaagagg ttgtgacaag
     6001 acttttgtca cagccttttt tgtttataaa aataaaagtt gtagtggagg ctacgaagtt
     6061 tactttgtct ttttacactt aatatttttt tgccaatttg gaatcaggat gttttgataa
     6121 ctatcgtttt caattgatgg aagctatatt gtttgctatc agtgaaataa ttatatggta
     6181 aacagtgttc tttttcttgt ttccattata aaaatcgtat cgggattttt cgttctttta
     6241 aattgaacat ttctatctat ccgcgtgtta tcaacaaaac aaaatcaggt aaatagttga
     6301 cgaaacagaa ataaatacat agtattatgt tttgaagcct aagtacaata gtctatagaa
     6361 aaggagcgat accattggca aaacgcattg accgaattta tatgtatgtc aaagaaaaaa
     6421 ccgctcattt aacaaaggca gaatatgatc aaggagtaac aacacaggaa attgctgaag
     6481 tgttagggat tcagcgaaca aatagcagta aagatctgaa tcagctagtg cgcgaaggaa
     6541 aactgataaa gacagacgga cgaccagtac gttacatata tcaaacactc gttacgcacg
     6601 taaagccagt tacaaaacat gtagtcagtt acaaagaaac gccggtctct gaagaaaaaa
     6661 atacactcca aatagatact aaggatatct ttgcaaaaat cattggagct aacggcagca
     6721 tgaaaaattc agtggaacag gcaaaagctg cgattttgta tccgccaaga ggattaaatt
     6781 gtttgattac aggacctacc ggatcaggaa agacttattt tgcacacgcg atgtatcatt
     6841 ttgcaaaagc gcatcatgta atagatgagg aaacggaact gattgttttc aattgtgctg
     6901 attatgccaa taaccctgag cttttgatga gtcatttatt tgggtacgca aaaggtgctt
     6961 ttacaggcgc agatgaagaa aaaatgggga ttatcgatca agcggatggc ggtatgctgt
     7021 ttttggatga gattcaccgg ttgccgcctg aaggtcaaga aatgatcttt tactttatgg
     7081 atcatggaac ttacagtcgt cttggggaaa caacgaaatc ccatgaagca aatgtacgga
     7141 tcgtaggtgc gaccacagaa gacccaggtt cttctctatt agaaactttt gttcggcgta
     7201 tcccaatcaa tatcaaactt ccggcttttg aaaaacgtcc tgcaaatgag aaagtcgatt
     7261 tagtaaaaat catgattgcc cacgaagcaa accgcacgca gcgaaagatt tctttgacag
     7321 aagatgtagc aaaagcattg atcggcagtg tgacctatgg aaatatagga caattgaagt
     7381 caaatatcca gttagtatgt gcacgaggat ttctaaatca tatgcaatca cccgaaatct
     7441 cgatcacaat cgatgatttg acagaaggga ttcgtagcgg attgattcaa ttagcaagca
     7501 accgcagtgc aatggcagag ctttctaaaa tattggagcc aaagataact gtagcaccaa
     7561 atgatacgat catgaaaatc caatcggact cctatgagtt accttataat ctatatgata
     7621 tcatcggaga taaagcagct ttactgaagt cggatggttt ggatcaagaa gcaatcaatc
     7681 atttcatttc tacagatatc aacatccatc tgaagtcttt ctataaagac catggttttt
     7741 cttttaatgc agacagcaaa ttagcagaat ttgtagatcc gaaaatcata gaagtgacca
     7801 atcagattta tgtaatggtc aaaagatctt taccatatga gtttcagcaa aactttattt
     7861 atgctatgag cttgcatatc agttcttttt tgaaaaaaat caacttagga gaagaacggc
     7921 atacgaatga taacatccgt gagatggctt ttgattttcc agatgaatat gctgttgcga
     7981 aagaagtgcg tagttatatc gaaacgtatt ttcaagtgga gattccagaa agtgaagact
     8041 attacttgac cgttctactc gtctcgttac gggcaaatca agcaagcggc agaatcggtg
     8101 tagtcgttgc agctcacgga aacagcacag caagcagtat ggtccaagtt gtccaacagt
     8161 tgttagatgc agagaacgta cgagcagtag acatgccttt ggatatggat ccgaaaacag
     8221 cattggaccg aattgaacgc aatgtacaag aagtagatga aggaagcggg gtcatactct
     8281 tagtagatat ggggtccctt gcgtcgttta attcgcaaat tcaaagagac actggaattc
     8341 cagtacgtac tgttgatatg gtaacaactt ctctagtttt ggaaactgta cgaaaggtct
     8401 cagtattagg gacagatcta gatatgttgc atgaatcatt gaaaaatttt cgaggttacg
     8461 cagaaatatc ttctgtagaa tctgttcagg aagcaaaacc tattcataag aaaaaagctg
     8521 ttttggctat ctgcgcatct ggcgaaggta cagcacaaag aatcaaagaa ttgatcgaac
     8581 gagcggtaaa caagcgtcaa gaaacagaat tagaagttct agctttgtcg attgtggaag
     8641 tgaaagaaga actgccagtt atccaaaaag aatatcagat catagctact actgggatta
     8701 ctgatttgaa tatccaagcc ccatttattc ctttagaacg ttttattgat caaaatatcg
     8761 aagtcatttt ggatcagttg ctgatggaat cagaattgga ggaaactgaa ttcatctccc
     8821 tagatgaaga gtcagctaaa aatacgtgtg ttgagtttat ctctgataac ttcatcttta
     8881 ttaatggtag taagttaatc gatccaatgt ggcaattttc tacacaaatc tctcagacga
     8941 cgggaatcgg cgatgaagaa tatggattca aaatcaacct agtgatgcac acagcaggaa
     9001 tgatcgaacg tattattcgg aatgaaccat tgactgtgga agaaaacgaa ttgacaaata
     9061 caacgaatga tcctctttat agccaattgg cagcctcagt tgttctgttg gaagatcaga
     9121 taaaagtaaa agtgccgata gaagaaatgt attatctgct acgtctagtc cataatcagt
     9181 tagataaaaa agaatacact gtgccatgaa tacacaaaaa cgatacactt ttatagtgta
     9241 tcgtttttgt gtattggtta agaatccttt aaattcaatt agtgtatcgt aaaaaagttg
     9301 gcacgctttt tgcttatagt agtgtgtgct aggaggtggt tgttcacaca gaaatgatag
     9361 gggtttctgt gaagtagtga ggaagaagga gttttgcaga tggatattcg attggcacgt
     9421 atagatgatc gtttaatcca cgggcaagtc gcaacagttt ggtcgaagca aacaggtgtt
     9481 gaacgtatca ttgtgatcag cgatgtagtc gctcaagata aattgagaaa gtttctacta
     9541 aaagaagctg caccgccggg gatcacagca aatgtaataa ccgtgcagaa aatgattcaa
     9601 atctatcata gtggattatt atcacgagca aaagtgatgc ttttattcac caatccccaa
     9661 gatgttgaag cggttgtccg ctgcggtgta cagttgaagt cgttgaatat cggcggtatg
     9721 agttttactg aaggcaaatc aatgattacc aattttgttt cagtaaatca acaagatatt
     9781 gattcctttc gttacttgaa cagtcaagaa gtggagttag agattcgaaa agtacctgct
     9841 gacaggaaaa tccttttgat ggaactacta gcgaaaatca aaaaggtgta gcaagaatgg
     9901 ttgttggaaa aggtcaaata attctgttgt aatggttagc aattattaat atttttgaat
     9961 ttgttacaac aaaagtaaat aggaggtata aatatggtag ggattatcct agcaagtcat
    10021 ggacaatttg ctgaaggaat cttacaatcc ggttcaatga tctttggcga acaagaaaac
    10081 gtcaaagccg tgattttgaa accaagtgaa ggtccagatg acttgagagc caaattggaa
    10141 gaagcggttg cttcttttga taatcaagac gaagtgttat tcttagttga tttatggggc
    10201 ggaacaccgt tcaatcaatc aaacacatta ttcgaagagc acaaagataa atgggcaatc
    10261 gtcagcggtt tgaatttacc aatgttgatt gaagcctacg catcacgctt ttcaatggaa
    10321 tctgctcatg aaattgcagc acacatcatt gaaacagcaa aagacggtgt aaaagtaaaa
    10381 ccggaagaat tagaaccggc agaagcaccg aaagcagcag ttgaagacgc acaacctaaa
    10441 ggagcacttc cagaaggaac tgtggtcgga gacggaaaaa tcaaatatgt attagcacgt
    10501 gttgactcac gtctgttaca tggacaagtt gcgacagctt ggacaaaagc agtgcaacca
    10561 aaccgtatta tcgttgtttc agatgcagta tcaaaggatg atctgcgtaa gagactaatc
    10621 gaacaagctg ctcctccagg tgtaaaagca aatgttattc ctattagcaa aatgatcgaa
    10681 gtagcaaaag accctcgttt tggaaatacc aaagcattgc ttttatttga aaatcctgaa
    10741 gacgtattga cagctgttga aggtggcgta gacatcaaag aattaaatgt tgggtcaatg
    10801 gcgcattcgg tcggtaaagt cgttgtaagt aaagtattgt ctatgggaca agaagacgtt
    10861 gaagcgtttg agaagcttga acaaaaaggt gtgaaattcg atgtacgtaa agtacctaat
    10921 gattcacgcg ataacatgga tgatattttg aaaaaagcaa aagctgaatt agcaaaagcg
    10981 taataaataa tattaaaatt tataggaggc ttatcatgtc tattatttca ataattttag
    11041 tcgtattagt tgcctttcta gctggtatgg aaggtattct tgatgaattt caatttcatc
    11101 aaccactagt ggcatgtaca ttgatcggtt tagttaccgg taacctcgaa gctggtatcg
    11161 tacttggcgg tacgcttcag atgatcgctt taggttgggc aaatatcggt gccgctgtag
    11221 caccagatgc tgcattagca tcagtagcat cagcaattat tttagtttta ggtggacaag
    11281 gtgttaaagg tgttccttct gcgatcgcga ttgccgttcc tttggctgtt gcagggttgt
    11341 tcttaacaat gatcgtacgt acaatcgctg ttccaatcgt tcatttgatg gatgcggctg
    11401 ctgaagaagg aaacatccgt aaggttgaaa tgtggcacat cattgctgta tgtttacaag
    11461 gggttcgtat cgcggtccca gcagcagcgt tgctatttat cccagcacaa actgtgcaat
    11521 cattccttga atcaatgcca gcatggttaa cagatggtat ggctatcggt gggggaatgg
    11581 tcgtagctgt aggttacgct ttggtaatca acatgatggc tacaaaagaa gtatggccat
    11641 tcttcgttat tggtttcgtt gtagctgcaa tttctcaatt aacattgatt gctctaggtg
    11701 ctttaggtgt tgcattagct cttatttact tgaacctttc taaaatgggt ggttcatcaa
    11761 ataatggagg cggaagcaac tctggtgacc ctttaggcga cattttgaat gactattaat
    11821 cttgaaggag gaaaataaaa tggcagaaga aaaaatcaaa ttatcaaaaa aagatcgttt
    11881 agctgttgcg tggcgctcta ccttcattca aggttcatgg aactacgaac gtatgcaaaa
    11941 cggtggctgg gcattttcta tgattccagc aatcaaaaaa ttatacaaaa caaaagaaga
    12001 acgttctgca gcattaaaac gtcacttgga attctttaat acacacccat acattgcttc
    12061 tccaatttta ggggttacat tggctctgga agaagaacgt gcgaatggcg cgcctgttga
    12121 tgatgtagcg attcaagggg ttaaagtagg tatgatgggt cctttagctg gtgttggtga
    12181 cccagtgttc tggtttacag tacgtccaat gctaggtgca ctaggtgctt cattagctat
    12241 gggaggaaat atccttggac caatcatctt cttcttaggt tggaacatta ttcgttgggc
    12301 attcatgtgg tatacacaag aatttggcta caaagctggt tctaaaatta ctgatgacct
    12361 ttctggcgga ttgttacaag acgtaacaaa aggtgcttca attttaggga tgttcgtatt
    12421 agctgccctt gtacaaagat gggtatcaat caaattctta ccagttgtat caactgtaaa
    12481 attagataaa ggtgcttaca tcgaatggga taaattgcct tcaggtggtg aaggaatcaa
    12541 gagtgcattt gaacaagtta ataatggctt agccctttct cctgaaaagg taacaacatt
    12601 acaagacaac ttagaccaat tgattcctgg tttagctgca ttaggattaa cattgttatg
    12661 tatgtggttg cttaagaaaa aggtttctcc aatcgttatc attcttggtt tattcgtagt
    12721 cggtgttgtt ggacacgtca tcggactttt ataatccata aaaatatagc tcgggcgttg
    12781 tcccgagctt tttttatata gtatactgtt cataaacaaa tatctggagg gagaaaatgg
    12841 ttcaatcaat caatacaaaa gtagacttgg taattgatgc tacttcgttt acgggtctga
    12901 cagattacgg gcaaatcatg ataggtgata atggttttga gttttaccat gcgcgagata
    12961 gacgcaaata tatccaaatt ccatgggaag aagtggatta tgtactagca tcagtcatgc
    13021 taaagggaaa atggattcct cgatatgcca ttcaaacgaa aaaaaatggt acatacacat
    13081 tttcttccaa agaacctaaa aaagtgcttc gtgcgatcag agaatatgta gatgaagata
    13141 gaatggtaca atcattgagt ttctttgatg tagtgaaacg tggtattcgt agtatgttta
    13201 aacgcaagta aaaaataaag aaaacttcta agaggaggtt ttctttattt ttttactttg
    13261 cagaagaaaa tatgaaatag caaaaccaat tatttgtccc ctttaaatcc catatgctaa
    13321 aattgattag caaagaagga ggttatatta tgagttggtt atggacattg attgttggag
    13381 ccgtgatcgg agcaattgca ggtgcgatca ccagtaaagg aaattcgatg ggctgtgtaa
    13441 cgaatatcat tgctggacta gtcggttcaa gtattggaca agcgattttc ggcgaatggg
    13501 gaccaaaagc tgcaggtatg gcacttattc catctatttt aggcgcagtg attttggtag
    13561 cagttgtctc atttttcttt ggaaaacgat cataagtttt tacaaaatag taaactaaaa
    13621 ggagttgcag cgagactgtg actccttttt ggctttattt atttaaaata aaaagaagtt
    13681 ttccggaaat ttttatttaa ctgtcgtgta cgaagaaaag tttgctataa tggaaaaaag
    13741 cgtgcaaaga aagagggagt ttcattatga tgctacgtgt agaaaaattg cgcaaaaaaa
    13801 tgcaagaaga aaatttggat tcatttttgg ttaccagtcc gtacaatctt cgttacttaa
    13861 cgaactttac aggtacgaca ggattagctg ttattacttt ggaaaaagca ttttttatta
    13921 ctgattttcg ttataccgag caggcggcag cgcaggctca agggtttgaa attattaaaa
    13981 atgtcggacc tatttttgat gaggtagcaa acttagtacg caaagaagaa ctgcactcat
    14041 tagcttttga ggaaacaaca gtctcatttt tagaatattc ggttttagaa gaaatcatcg
    14101 atgcggaatt agtacctgtt tcacagatga tcgaagaact cagagaagtg aaagatgaag
    14161 aagaaatcgc tattatcgaa aaagcatgtc atattgcgga tatggcatat gatcacatcc
    14221 tgaaaatgat ccaaccgggc atgactgaga ttgaagtcgc aaatcaacta gacttttata
    14281 tgcgttctct tggcgcttca ggtgtttctt ttgatacgat cgttgctagc ggattgcgtt
    14341 cggctatgcc gcatggtgta gcaagcaaaa aaatcatcga acaaggtgac ttgatcacat
    14401 tggactttgg ttgctattac gaagggtacg tttccgatat gacacgtaca ttcgctattg
    14461 gtgatcctgg ggaaaaatta aaagaaattt atcaaatagt cttagatgct caattagcag
    14521 ttattgatgc tgcaaaacca ggaatgactg gtgtccaatt agatgcagtt gctagagatt
    14581 atatttcaaa acatggttac ggggaagcat ttggacattc tacaggacat gggatcggtt
    14641 tagagatcca cgaaggacca aacgtttctt ctcgtgcaga aaagcaattt gtaccaggaa
    14701 atgtgatcac tgatgaacca gggatctact taccaggaat cggtggagta cgtattgagg
    14761 atgacttgtt gatcacagaa gatggaaatc gtgtgttgac tcgttcacca aaagaattga
    14821 tcatcttata gtttcatcaa tagaagaagt aagcgtaaaa atcagtgttc acagactttg
    14881 ttatagaaaa tcactcgatt taatgataca ctatagaaga acttttaagc tgtaagagat
    14941 aataaagttg ggtgttttct ccaattcata gcagtttgca gctgatcggc ggcagttttc
    15001 ttaccacgtg atcactatgc cgcatcatag agaattcgga tgtatctcgt gcttaggcaa
    15061 agggaggaat aaataaatgg cagatgaaaa aaatttgatt ttaaacgcaa accaagattt
    15121 aggagagatc gtgatcgctc ctgaagtcat cgaagtaatt atcgggattg cagcttctaa
    15181 agtagaaggc gtatacggaa tgcgcggaac ttttgccagc aatgtcactg aattattagg
    15241 acgtgcagct cacggaaaag gtgtttactt agcaaacgag gaagatggct tgaaagtaga
    15301 tctttactgt tatctagaat atggtgtttc agttcctaaa gtagcaatgg aaatgcagga
    15361 acgggtcagc cagcaagtcc ttttcatgac ggatatcgat ttatctgaag tcaatatcca
    15421 tgtagtagct gttgttcctg aaaaattaga acaaccaaca atcgaagaac tttttgaaga
    15481 cgaagaggaa gagaatgaat aaagaattat caagacacga gattcgggaa atggcattgc
    15541 aggctttatt tccattagac ttcaatgcag acctaacaaa agaagatgcg attttcaacg
    15601 caatcgaatt agaccaccgc gacatgatca acgaagatga atcagagttt gttcctgttt
    15661 atcttgatac gctagttggc ggtgtctgtg caaaaaaaga tgaattggat aaagtgattg
    15721 aaaaacattt aaaaaacaat tggcacatca atcggatctc aaaaatggat ttggtgatct
    15781 tgcgtatcgc gatttttgaa atgacttatg tgacagatgt accagcggct gttgctttaa
    15841 atgaagcaat cgagttggca aaaacattta gtgatgaccg ttcacgtaaa ttcgtcaacg
    15901 gtgttttatc caatgtattg aaagaattag aagctggggc gtaagtccta gct
//
LOCUS       DAZKNV010000058        15745 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000058 DAZKNV010000000
VERSION     DAZKNV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15745
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.058"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            54..626
                     /locus_tag="ACG8M1_002168"
     CDS             54..626
                     /locus_tag="ACG8M1_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFQ0422843.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            771..1475
                     /locus_tag="ACG8M1_002169"
     CDS             771..1475
                     /locus_tag="ACG8M1_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0422844.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1703..2041
                     /locus_tag="ACG8M1_002170"
     CDS             1703..2041
                     /locus_tag="ACG8M1_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422845.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFNITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2026..2880
                     /gene="lgt"
                     /locus_tag="ACG8M1_002171"
     CDS             2026..2880
                     /gene="lgt"
                     /locus_tag="ACG8M1_002171"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFQ0422846.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3027..3260
                     /locus_tag="ACG8M1_002172"
     CDS             3027..3260
                     /locus_tag="ACG8M1_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFQ0422847.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3458..5362
                     /locus_tag="ACG8M1_002173"
     CDS             3458..5362
                     /locus_tag="ACG8M1_002173"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0422848.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPTEKVKIS"
     gene            5716..6081
                     /locus_tag="ACG8M1_002174"
     CDS             5716..6081
                     /locus_tag="ACG8M1_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFQ0422849.1"
                     /translation="MTAEVCTTTCIHKEKVASVKNNLKDKDLSTLLVLGKCFSDSSRI
                     KIFYALETYKEMCVCDLAAILNASIATTSHHLRFLKKNGMAKSRQYGKVVYYSLANED
                     ILSAIHVFLKLSENLSMKS"
     gene            6098..6711
                     /locus_tag="ACG8M1_002175"
                     /pseudo
     CDS             6098..6711
                     /locus_tag="ACG8M1_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010620830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
     gene            complement(6823..7143)
                     /locus_tag="ACG8M1_002176"
     CDS             complement(6823..7143)
                     /locus_tag="ACG8M1_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFQ0422850.1"
                     /translation="MNSLSTSPLKNESIQEVSKIFKMISDPTRLSILFLLQKEELSVG
                     AIAHSLSMEQSAISHQLKTLKTSRLVKSKRAGKNMIYSLDDLHIFSILEQVSTHIEEQ
                     EKEK"
     gene            7399..9306
                     /locus_tag="ACG8M1_002177"
     CDS             7399..9306
                     /locus_tag="ACG8M1_002177"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0422851.1"
                     /translation="MKEIQEQHSHENNSHDHGKMPIILYFIGLALSLIALFVNGENNL
                     IQNTLFSIASISAGYHVIILEGIGETIENSKRQHKFTPNSHILMGIAAIGASLIGNFW
                     EGTLLVLIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLIMQDGNTTIVNVSELKVG
                     DQLQVLNGDQVPIDGVIVSGSTSIDESSINGESIPKEKSKGDGVFGSTINGTGTFTME
                     VTKETNDTVFSKILQLVNQNQENQTKASSIIQKFEPKYVKFVLIAIPLFILLAPMLFD
                     LTWSQSIYRGLVLLVAASPCALAAATVSVTLSATSNLAKRGVLSKGSAYLSQLADIQA
                     IAFDKTGTLTKGKPEVTNYYFSDSVNEENMIDIVVALEKESNHPLASAILDKFEPKNK
                     LAIEVENQIGKGLIGDYNENTYRIGKPTSFEAVSDDYTRLNKEWASEGNTVVYVSENE
                     KVIGLIALMDIPSEHAKATIDYFKKCGIHTTLITGDSEMTGQAVGKQLGVDQVIANVM
                     PEDKSNIINEQKETYGITAMVGDGINDAPALVKADVGIAMGEGTDVAVDVSDLVLMKN
                     DLSKLVKAHEISLKMNRVIWQNIIFSMVVVAFLITVSLVGLTDIAISVIVHEGSTLVV
                     ILNGLRLLKSK"
     gene            9400..9621
                     /gene="relB"
                     /locus_tag="ACG8M1_002178"
     CDS             9400..9621
                     /gene="relB"
                     /locus_tag="ACG8M1_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFQ0422852.1"
                     /translation="MTVISLRIDTQEDKLIKEYAKAKNISVSALIRSSVLEKIEDEID
                     LGLYNQAMKDHKENPKSISFEDMLKELSD"
     gene            9622..9894
                     /locus_tag="ACG8M1_002179"
     CDS             9622..9894
                     /locus_tag="ACG8M1_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0422853.1"
                     /translation="MSSGYQVEFEKGAQKALKKMDKYQSLLIMGWIQKNLVNCTDPRQ
                     HGKGLTVNRSGEWRYRIGDYRLIADINDETVTILMLEIGHRKNIYK"
     gene            complement(10025..12991)
                     /locus_tag="ACG8M1_002180"
     CDS             complement(10025..12991)
                     /locus_tag="ACG8M1_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFQ0422854.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            13137..13712
                     /locus_tag="ACG8M1_002181"
     CDS             13137..13712
                     /locus_tag="ACG8M1_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0422855.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            13926..14621
                     /gene="vanR-A"
                     /locus_tag="ACG8M1_002182"
     CDS             13926..14621
                     /gene="vanR-A"
                     /locus_tag="ACG8M1_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFQ0422856.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            14599..>15745
                     /gene="vanS"
                     /locus_tag="ACG8M1_002183"
     CDS             14599..>15745
                     /gene="vanS"
                     /locus_tag="ACG8M1_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFQ0422857.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKR"
BASE COUNT         5059 a         2657 c         3201 g         4828 t
ORIGIN      
        1 aggaatcaaa gaaagctatt ttaaacaaac caaaattata ggaggaataa atcatgactg
       61 aaaataaagc tactcaagaa agaacacccc aagaaagatt gcaagaagaa caagaacaca
      121 aggaacatgt tcatcatacg aaaattaatg cagcggccat tgcggatcat cttttaggca
      181 acatgcatac attacatgtg aaactgcacc aatatcactg gtatgtaaaa ggagccaatt
      241 tctttacgtt gcatgaaaaa tttgaagagt tgtataacga aaatgaaaaa tggttcgaca
      301 aacttgcgga gcgtctaatt acttctgggc ataaacctgc ttcgacaacg gttgaatttg
      361 aaaaatattc gatgctttcg gaagatgcag ttaataaata cgctaaagca gaagacatgg
      421 ttgaaaatat tatcgaggac ttcagaagca ctcgtgacct aactattcgc gcgattcgtt
      481 tagctcaaga cgagggtgac gatgctttag aagatacatt gattgctttt aaaaatgact
      541 tagacaagaa catttggatg ctgcaagcgt tcattggtaa agaagcatta gaagatgatg
      601 acgctcttga tgaggatgaa gattaaggta aaagtagaag ctgatttagg gattggaatt
      661 ctttccagtc ctttttccat tttcttgatg tgcatcaatt tttttgtagt aagagactta
      721 tataataaaa gcagcgaata taaacaaaat aaataaaggg ggagaatgaa ttgactaaac
      781 atacccatca tgaaattggc gaccacgcag cctgtatccg cttggttcca atattcaatc
      841 acttagagga tagcgcgatg aattacattg ctgaaaaagc ccacacgaaa cagtatcaaa
      901 aaggagagtt tctgtttcgt tcacaagaaa aagaggatac tttatatatt atcaatcgtg
      961 ggaaaatccg tatttatcga ttggcagact ctggcaaaga gcagctagtg cggatcttga
     1021 accctggtga tttcaccgga gaatggacct tgttcaaccc ggatgcagta cacgaggaat
     1081 atgccgaagc aacccgagat accgttgtct gtatgattca gcaaaaagat gtccaagatt
     1141 ttctggaaca atacccagct atttctttaa aactattggc ggaaatgtct aaacggttag
     1201 aaagttcaga acgtcaaacg acacaagtag ccgtggagag tgtcattacc cgtttagttt
     1261 tgtttttggc agaaaatgtg gaacctgaaa tgggcaactc tcccaccatc accctgccga
     1321 tggcaaaaaa ggacattgct tcctatttag gaacgacacc tgagaccatc agtcgcaaat
     1381 ttggagaatt ggaggacgag ggattgattc aacagctgtc tgggaaaagg atcaagattc
     1441 aggatttaga tgatttattg ctttacagcg aataatcgga cacacttttt tctacacgtt
     1501 ggtgttctgt cgctcttcat taacaacggg acagaactca gtgcttttgc ttccatctgt
     1561 ccgtttttag cttttttaag acagaacgac cttcattcat tggaaaaata aaagcacaaa
     1621 catgataacc ctcaagtttt tttgttttat ttttctttaa gatagggttg tcgaacaaaa
     1681 cgtaaaaata agtagggtga atgtgcattg tttttgggtg atagttgcca tcacgttgtc
     1741 agcagcgggt gcattctttg tcgtcccttt caccaagaac acgattggcg gcgaagcaaa
     1801 aacgtctaac gttgttgagg cagataggtt agctatggaa aaagaagagg aagttgtaaa
     1861 aggagccggc gtaatcggac acggaaaagt ggcgtattac gaagcgagtg accagggaga
     1921 taaaagtgta ttcactgttt ggtttccatg gagcttagcc ggaatcttgt tcaacatcac
     1981 catgactaga atgacgcgaa aaattgaaga aatggagcaa atagaatggg attcgtatta
     2041 ggcgttttga atccccatgt ggtggagatt ggttctgttg tgattcattg gtatggagtc
     2101 attattgcag cgggcatatt agcggctctc cagttgagca ccaaggaagc aaagaaaaaa
     2161 ggactggaag aggataccat tatcgatatg gccttatggg caattccgat tggactcctc
     2221 ggcgctcggc tttattatgt gttatttgaa cttggttatt atctgcaaaa tccaggacaa
     2281 atccttgcga tttggaatgg cggcattgcg atttatgggg gattgattgc aggagggggt
     2341 acgctatatt ggtatgcaaa gaaaaaaggt acttctttgg cactcgttct tgatatttta
     2401 gcgcccaatg tattgttagc ccagtccatt ggtcgttggg gcaattttat gaatcaggaa
     2461 gctcatggtg ggccggttac tcgtcaattc ttggaaaatc tttatttacc tgaatttatc
     2521 attgaacaaa tgaatatgaa tggtacctac taccatccga cttttttata cgagtcattg
     2581 tggagtttgt tgggctttgt cctcatcgtc actatacgga accgaaaaca gcttttgcgt
     2641 caaggagaag tcgctttgag ttacgttttg tggtactcag tgggtcggtt cttcattgaa
     2701 ggtatgcgaa cggacagttt atggattggc gagtggatcc gcgtttcgca agccttgtct
     2761 ctggccctgt ttattggcgc gattgtagta tggtttatac gcagacaaga ttatccacca
     2821 atttcttatt attctgatgg caataagggg cagaaaaaga ctattaagat ggtgaattga
     2881 gcaaaaagat aaaaagaagt gcaaaacttg atatgcgtca attttcgttt gctaaaagtg
     2941 agctatacta cagttgtaaa gaggaaaagg cagtgttcat taatctgctg ccgataaaat
     3001 aaaaacacat aaaggagata ggaattatgg aaaaagctat attgcaatta gaaacgttgt
     3061 cttgtccaag ttgtatgcaa aaaattgaag gtgccgtgaa atcagttaac ggtattgata
     3121 aagacagcat taaagtatta ttcaactcca gcaaagtcaa aaccaatttt gattcagctg
     3181 tcacttcgat tgaagagatt caaaaagcta tcgaaaacgt aggctatccg gttcttaaag
     3241 caaaagtcaa ggccgtttaa cagattaaat gaactaggca attctggaag aaaagctatt
     3301 tttccaggat tgcttttttt gttgcaatcc gattcgaggt gcttagaaac gataaaagag
     3361 aactttctaa acttgatgtc agtcaattaa ttacttaggc aattatctta tactgtgttt
     3421 atcaataaaa gagaaattaa atttggaggg aaaaagcatg caacaatata tattaagcaa
     3481 gaaaaatgtt atcaccgtca tcagtggatt gttaatcgta ctcggtttct tcagtcactt
     3541 tgttttagaa aacgtaggac tttcagagtg gtctttgatc atcgcctctg tctttgggat
     3601 tacgccaatt gccattcaag cgtttcaagc aatgaaagtc aaagtcatca gtattgatgt
     3661 cttagtcagt attgcagcga ttggtgcgct ttttattcaa aattatgaag aatcggctat
     3721 tgtcacgttc ttattcttat tcggacacta cttggaacaa cgaacattga accaaacgcg
     3781 atctgctatc aaagaattga ctgaaatggc acccgaaagc gccttgaaac aaatggataa
     3841 tggcgaattt gaagaagtag aagtggatga tatagatgaa ggggatatct tgctcgttaa
     3901 aacgggtgcg aaagttccag tagatggcat agtccttacg ggtgaagggc atatcaatga
     3961 agctagcatt acaggtgaag ctattccggt caacaagcta gctgatgcag aagtttttgc
     4021 aggaaccatt ttagaaaacg gaacgattca aatcagagct gaccgagttg gtgaggacac
     4081 cacatttgga aaaattattg aactcgtgga agaagcacaa gattctaaat ccgaagcgga
     4141 acggttcatt gatcgctttt ctaaatacta cacaccagct gtcttggttc tggcaattgt
     4201 tgtatgggcg ttcagtcaaa atattgagtt agcaatcacc atcttggttc taggttgccc
     4261 aggcgcatta gttatcggag tgcctgtctc aaacgttgcc ggtattggga atggtgctcg
     4321 taacggtgtt cttttaaaag ggagtgaagt cattcaagac ttcagtaatg tggatacaat
     4381 tgtatttgat aagacaggta ctttaactgt cggaaaccca accgttgcag cgactgaact
     4441 gtatgaaaaa gatcctgctg aaacgcttgg ctatctggcc agtgtggaac gggaatcaga
     4501 tcatccatta gcaaaagcgg tcttaaatca aattggagaa acaaactttt atcctgttga
     4561 aggaactgaa gttgtgaaag gcggcggaat cgtttcaagt gtagctggac atagagtggc
     4621 tgttgggaat gtggccttga tggaaaaaga aaatgtcact ctcagcaaaa aagtgcaaaa
     4681 agatgtcaaa cggtttgaac aacaagggaa ctctctcgtt ttgacagcgg tcgacggtga
     4741 attaaaagta ctgatgggca ttcgcgatca agtccgtccg ggtgtgaaag ctaatttgca
     4801 ggaattaaaa gacttgggcg tgaaaaatct agtcgttctt tcaggagata accaaggaac
     4861 cgttgatgtg gtcgccggcg aacttggttt gaccgaagct cacggctaca tgttgccgga
     4921 agacaaatcg gcttatatcg gaaaacttca acaacgtggt caaattgtag cctttgttgg
     4981 agatggcgtt aacgatagtc cgtccttagc tttagcagac attggaatcg caatgggaag
     5041 cggaacggac gtagcgattg aaacatccga tgtcgtttta atgaactcga acttcagcaa
     5101 cttgcctcac gcattaggat tagtaaaagc caccgcaaat aatatgaaac aaaatatcgt
     5161 gatttcagtt ggagtagtgt tggtcttgtt gaccagcgtc ttcttcagcg aatggatgaa
     5221 tatgtctatc ggaatgttgg ttcatgaagg tagtatcttg gtggtaattt tcaatggcat
     5281 gagattaatg aagtataagt tgaaaggtcg gaaagaacaa aaagaagtat cagcacctac
     5341 agagaaagta aaaatatctt aagaataaat tagaagaggc tgagacaata gtccatcctt
     5401 gaaatgacaa aagcggaaac tcagattttt aaatctggga ttttccgctt ttttgagttc
     5461 ttgaaaaaaa ataagagtat agagtatgtt ctttataaaa ttaattttcg tgtaaattat
     5521 taaaaattta ataataaaat ttaaattcct attaagttgt aacacatgaa attgcttaaa
     5581 atagtgtatc aaaaaccttg ttttattaat gttgaattta tttgaaaggt ctacagatta
     5641 acatattatt gacaaaacaa tatttaaata gttatacttc attcaaacgt ctgtttgaac
     5701 gaggtggtga agttaatgac tgcagaagta tgtacaacta cttgtataca taaagaaaaa
     5761 gtagctagtg ttaaaaataa tttaaaagat aaagaccttt caactttact tgtattagga
     5821 aaatgtttta gcgattcttc taggattaaa attttctatg ctttagaaac gtataaggag
     5881 atgtgcgttt gtgatttagc agcgatactt aatgctagta ttgctacaac gtcacaccat
     5941 ttacgttttt tgaaaaagaa cggaatggcg aaatcacgtc aatatggaaa ggtagtttat
     6001 tactctttag cgaatgaaga catcctttcc gctattcatg tttttttaaa gttatcagaa
     6061 aatctatcta tgaaatctta gtttggagga agttattttg ttacaaagta ttttttcagc
     6121 tatcgctgtt tatatttcta ccagcattga ttatttgttt atcttgctga ttattttttc
     6181 tcaaagtcat acaaaaaagg gctccgtcag attttttggg gtcaatatct aggaacaggt
     6241 atcttagtag ccgtaagttt atttgcagca tatgtgctga atttcattcc gcaagattgg
     6301 atcattgggc ttctcggtct aattccgatt ttcttaggaa tcagagtggc attggttggc
     6361 gaagaggagg aagaagaaga ggaagtcgtt gaaaagcttg aatcaagagg aacaaaccgc
     6421 ttcttttgga ccgttgcctt aataacaatt gcttctggtg gcgataactt agggatttat
     6481 attccttact ttgcctcgtt atctttttca gagattgtca ccgctctaat cgtatttgct
     6541 atttctgttg cggttctttg ctatatcagt tacaaattag ccaagatttc ttttgtttcc
     6601 gaaaccttag aaaaatatga acgaatcctt gttcctatag tgtttattgg cttaggaatt
     6661 tatattttga tagaaaatgg gacgattcaa acactattaa attttatata aacaactacg
     6721 atagtgaagt tcaaataaaa aaagacagcg agattttaac tcgctgtctt tttttatttg
     6781 aactaatgaa ttgtaaaatc attttaacct tgtagtttgt ctttattttt ctttttcttg
     6841 ttcttcgata tgagttgaaa cttgctcaag aatactaaaa atatgaagat cgtcaaggct
     6901 ataaatcata tttttaccag ctctttttga ttttactaat cttgaagtct ttaaagtttt
     6961 taactggtga gaaattgctg attgttccat actcaaagaa tgcgcaatag ctccaacgct
     7021 aagttcttct ttctgcagaa gaaataaaat tgaaagtcgg gtagggtcac tgatcatttt
     7081 aaatatttta cttacctctt ggatagattc attttttaat ggagaagttg ataatgaatt
     7141 cataagaatt tctctccttc atatgtttgt ttattcacat ttagattatc ataatatttt
     7201 tataaagcaa gattttttgt ataagggtag ctattttaga gtcctatttt ttttatcacc
     7261 taaataagat aactattttt ttgacaaatt agatagagcg atataaaatg aatgtataga
     7321 catatgaatg ttcgttcaaa cgtaattcgt aagcattacg atttctaaaa aaaagtttta
     7381 ttaagaaagg tgatagaaat gaaagagatt caagagcaac actcacacga aaataatagt
     7441 cacgatcatg ggaaaatgcc aattattttg tactttattg gtttagcatt gtcgctcatt
     7501 gcgttatttg taaacggaga aaataattta atccaaaaca ctttgttttc aattgcttca
     7561 attagtgctg gttatcatgt cattattctt gaaggaattg gagaaacgat tgaaaactca
     7621 aaaagacaac acaaatttac ccctaattct catattttaa tgggaatagc tgcaataggt
     7681 gcttctctga taggaaattt ttgggaagga acgttattgg ttcttatttt ctctggagca
     7741 cattttcttg aagattatgc tgaaggaaga agtaaaagag aaattaccaa gttattagaa
     7801 atgaatccaa caacagctag gctaatcatg caagatggca atacaacaat cgttaatgtt
     7861 agtgagttga aagtaggaga tcaacttcaa gtgttaaacg gtgaccaagt accgattgac
     7921 ggagtaatag tatcaggctc tacttcgatt gacgaatctt ctattaatgg tgagagtata
     7981 cctaaagaga aatcaaaggg agacggagtt tttgggagta caattaatgg aacgggtacc
     8041 tttactatgg aagtcacaaa agaaactaac gatactgtct tttcaaagat tttacaacta
     8101 gtgaatcaaa atcaagagaa tcaaacaaaa gcgtctagta ttatccaaaa gtttgagcct
     8161 aagtatgtta aatttgtttt aattgcaatc ccactcttca ttttacttgc tcctatgctg
     8221 tttgatttga catggtcaca aagtatttat agaggattag tccttttagt cgcagcttct
     8281 ccgtgtgctt tagcagcagc taccgtatcc gtaacattgt cagccacttc taatctagca
     8341 aaaagaggcg tactttcaaa aggaagtgcc tatttgtccc aattagcgga tattcaagcc
     8401 attgcctttg ataaaacagg aacattaact aaagggaaac cggaagtaac caattattac
     8461 ttttctgatt ctgtgaacga ggaaaatatg attgatatcg tagtggctct tgaaaaagaa
     8521 tcaaatcacc cgttagcaag tgctatttta gacaagtttg aaccaaaaaa taaactagct
     8581 attgaagtgg aaaatcagat tggaaaaggt ttaataggcg attataacga aaacacttat
     8641 cgtataggta aaccaacttc ttttgaggct gtatcggatg actatacacg tttgaataaa
     8701 gaatgggctt cagaaggtaa tacggttgta tatgtatcag aaaatgaaaa agtaatcggc
     8761 ctgatagcat taatggatat tccaagtgaa catgcgaaag caactataga ttactttaag
     8821 aagtgtggta tccataccac tttaattact ggggattctg aaatgacagg gcaagctgtt
     8881 ggtaaacaat taggagtaga tcaagtaatt gcaaacgtca tgccagaaga taaatctaac
     8941 attatcaatg aacaaaaaga aacctatggt ataaccgcta tggtgggaga tggtataaac
     9001 gacgcacctg ctcttgtgaa ggcagatgtt ggaattgcta tgggagaggg tacggatgtt
     9061 gcagtagatg tatctgatct agtattaatg aaaaatgatt tgtctaaatt ggtaaaagct
     9121 catgaaattt ctttaaaaat gaatcgagtt atttggcaaa atattatttt ctcaatggta
     9181 gttgtcgctt ttctaattac cgtaagctta gtaggattaa cggatatagc cattagtgtg
     9241 attgttcatg aaggaagtac cttagtcgtg atattaaatg gtcttcgatt attaaagtct
     9301 aaataaatac atgaaattgg ataaaatcat gtatctaaag tttgcagcct ctctaatttt
     9361 gtattacaat gtatatacaa aaagaagggg gtgattctaa tgactgtcat atcgctcaga
     9421 attgatactc aggaagataa attaattaaa gaatatgcta aggcgaagaa tatttcggtt
     9481 tcggctctga ttagaagttc tgtcttggaa aaaatcgagg atgaaattga tttgggccta
     9541 tataatcaag ccatgaagga tcataaagag aatccgaaaa gtatttcttt tgaagacatg
     9601 ctaaaggagc tatctgatta aatgagctca ggttatcaag tcgagtttga aaaaggagct
     9661 caaaaagcgt taaaaaaaat ggacaaatac caatcccttt taattatggg atggattcaa
     9721 aagaatctag tgaattgtac cgatcctagg cagcatggaa aaggattaac cgtcaatcga
     9781 tcaggcgaat ggcgctatag aatcggtgat tatcgcttaa tagctgatat caatgacgag
     9841 accgtaacca ttttaatgtt agagattggt catagaaaaa atatttacaa ataaaccatt
     9901 caaattgagt gcaagcatgt ttaataaaaa aggattctac tgctttttaa ggggtagcgt
     9961 caggaaaatg cggatttaca acgctaagcc tattttcctg acgaatccct cgtttttaac
    10021 aacgttaaga aagttttagt ggtcttaaag aatttaatga gactactttc tctgagttaa
    10081 aatggtattc tcctagtaaa ttaatatgtt cccaacctaa gggcgacata tggtgtaaca
    10141 aatcttcatt aaagctacct gtccgttttt tatattcaac tgctgttgtt aggtggagag
    10201 tattccaaat acttatagca ttgataatta tgtttaaagc actggctctt tgcaattgat
    10261 gctgtatggt gcgttctcta agctcacctt gttttccgaa gaaaatagct cttgccaatc
    10321 cattcatggc ttctccttta ttcaatcctc tttgtatttt tcttcttaat gattcatccg
    10381 atatataatt caaaataaag atcgtttttt ctattcggcc catctcacgt aaggctgtag
    10441 ctaagctgtt ttgtcttgaa taggaaccta gcttccccat aataagggat gctgaaactg
    10501 ttccctccct tatagaatga gctaatcgca aaacatcctc ataattttct ttaatgacct
    10561 ttgtatttat ttgtccacgt aaaatggctt ctagttttgg atactcactt gctttatcta
    10621 tcgtaaataa ttttgagtcc gataaatccc ttattcttgg ggcaaattta aatcctaata
    10681 aatgagtcag tccgaatatt tggtcagtgt aaccggcagt gtctgtataa tgttcctcta
    10741 tgtttagatc cgtctcatga tgtaacaaac catccaaaac atgaatcgca tctcttgaat
    10801 tagtatgaat aatctttgtg tagtaagaag agaattgatc acttgtaaat cggtagatgg
    10861 tggctccttt tccagttcca taatgtggat ttgcatctgc atgtagtgat gaaacaccta
    10921 gctgcattct cataccatct gacgaagatg ttgtaccgtc gccccaatag aaaggcaatt
    10981 gtaatttatg atgaaagttt actaatatgg cttgggcttt attcatggca tcttcataca
    11041 tgcgccattg agatacattg gctagttgct tatatgtaag tccgggtgtg gcttcggcca
    11101 tcttgctcaa gccaatattc attcccattc ctaaaagggc agccatgata atgattgttt
    11161 cttccttatc tggttttcga ttattggaag catgagtgaa ttgctcatga aatcctgtta
    11221 tatgggccac atccatgagt aaatcagtta attttattct tggtagcatc tgataaaggc
    11281 ttgcactaaa tttttttgct tcttctggaa catctttttc taagcgtgca agtgatagct
    11341 ttcctttttc aagagaaacc ccatctaact tattggaatt ggcagctaac cactttaacc
    11401 tttcattaaa gctgctggtt ctctccgtta tataatcttc gaatgataaa ctaactgata
    11461 atctcgtatt ccccttcgat tgattccatg tatcttccga aaacaaatat tcctcaaaat
    11521 ccctatattg tctgctgcca acaatggaaa catctcctgc ccgaacatgc tcccgaagtt
    11581 ctgttaaaac agccatttca tagtaatgac gattaattgt tgtaccatca tcctcgtata
    11641 aatgtctttt ccatcgtttt gaaataaaat ccacaggtga gtcatcaggc acttttcgct
    11701 ttccagattc gttcattcct cggataatct caacagcttg taaaagtggc tcatttgcct
    11761 ttgtagaatg aaattccaat actcttaata gcgttggcgt atattttctt agtgaataaa
    11821 accgtttttg cagtaagtct aaataatcat agtcggcagg acgtgcaagt tcctgagcct
    11881 cttctactga agagacaaag gtattccatt caataaccga ttctaaaacc ttaaaaacgt
    11941 ctaatttttc ctctcttgct ttaattaatg cttgtccgat gttcgtaaag tgtataactt
    12001 tctcatttag ctttttaccg ttttgtttct ggatttcctc ttgagcctta cgaccttttg
    12061 ataacaaact aagtatttgc ctatcatgaa tttcaaacgc tttatccgtt agctcctgag
    12121 taagttgtaa taaatagatg gttaatatcg aataacgttt attttcttga aagtcacgga
    12181 atgcatacgg ctcgtatctt gagcctaagc gagacagctg caacaggcgg ttacggtgca
    12241 aatgactaat ttgcactgtt tctaaatcca ttcctcgtat gtattcgagt cgttctatta
    12301 tttttagaaa agtttcgggt gaaggatgac ccggtggctc ttttaaccaa cccaatatcg
    12361 ttttattgga ttcggatgga tgctgcgagg taataatccc ttcaagcttt tctttttgct
    12421 catttgttag agatttacta accgtattaa atagcttctt ttcagccatt gcccttgctt
    12481 cccacaccat tctttcaagt gtagtgatag caggcagtat aattttgttt tttcttagaa
    12541 aatctatgca ttcatgcagt agatgaatgg catcaccatt ttccaaagct aattgatgaa
    12601 ggtacttaaa tgtcattcga tattcactca gggtaaaagt tacaaagtcg tattcacttc
    12661 gaatttcttt caaatgatcc caaagtgtat tttccctttg aggataatga tcaagcgagg
    12721 atggactaac accaatctgt ttcgatatat attgtatgac cgaatctggg atgcttttga
    12781 tatgagtgta tggccaaccg ggataccgaa gaacagctaa ttgaacagca aatcctaaac
    12841 ggttttcttc cctccttcgc ttattaacta tttctaaatc ccgtttggaa aaagtgaagt
    12901 aggtccccag tatccattca tcttcaggga tttgcataaa agcctgtctc tgttccggtg
    12961 taagcaattc tctacctctc gcaattttca ttcagtatca ttccatttct gtattttcaa
    13021 tttattagtt caattatata tcaatagagt gtactctatt gatacaaatg tagtagactg
    13081 ataaaatcat agttaagagc gtctcataag acttgtctca aaaatgaggt gatattttgc
    13141 ggaaaatcgg ttatattcgt gtcagttcga ctaaccagaa tccttcaaga caatttcagc
    13201 agttgaacga gatcggaatg gatattatat atgaagagaa agtttcagga gcaacaaagg
    13261 atcgcgagca acttcaaaaa gtgttagacg atttacagga agatgacatc atttatgtta
    13321 cagacttaac tcgaatcact cgtagtacac aagatctatt tgaattaatc gataacatac
    13381 gagataaaaa ggcaagttta aaatcactaa aagatacatg gcttgattta tcagaagata
    13441 atccatacag ccaattctta attactgtaa tggctggtgt taaccaatta gagcgagatc
    13501 ttattcggat gagacaacgt gaagggattg aattggctaa gaaagaagga aagtttaaag
    13561 gtcgattaaa gaagtatcat aaaaatcacg caggaatgaa ttatgcggta aagctatata
    13621 aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct agggcttcat
    13681 tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta atgggcaata
    13741 tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat gccgaaaagc
    13801 cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt atgtaaatgc
    13861 ttataaattc ggccctataa tctgataaat tattaagggc aaacttatgt gaaagggtga
    13921 taactatgag cgataaaata cttattgtgg atgatgaaca tgaaattgcc gatttggttg
    13981 aattatactt aaaaaacgag aattatacgg ttttcaaata ctataccgcc aaagaagcat
    14041 tggaatgtat agacaagtct gagattgacc ttgccatatt ggacatcatg cttcccggca
    14101 caagcggcct tactatctgt caaaaaataa gggacaagca cacctatccg attatcatgc
    14161 tgaccgggaa agatacagag gtagataaaa ttacagggtt aacaatcggc gcggatgatt
    14221 atataacgaa gccctttcgc ccactggagt taattgctcg ggtaaaggcc cagttgcgcc
    14281 gatacaaaaa attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc cactccggcc
    14341 ttgtcattaa tgttaacacc catgagtgtt atctgaacga gaagcagtta tcccttactc
    14401 ccaccgagtt ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg gttagctccg
    14461 agctgctatt tcatgagata tggggcgacg aatatttcag caagagcaac aacaccatca
    14521 ccgtgcatat ccggcatttg cgcgaaaaaa tgaacgacac cattgataat ccgaaatata
    14581 taaaaacggt atggggggtt ggttataaaa ttgaaaaata aaaaaaacga ctattccaaa
    14641 ctagaacgaa aactttacat gtatatcgtt gcaattgttg tggtagcaat tgtattcgtg
    14701 ttgtatattc gttcaatgat ccgagggaaa cttggggatt ggatcttaag tattttggaa
    14761 aacaaatatg acttaaatca cctggacgcg atgaaattat atcaatattc catacggaac
    14821 aatatagata tctttattta tgtggcgatt gtcattagta ttcttattct atgtcgcgtc
    14881 atgctttcaa aattcgcaaa atactttgac gagataaata ccggcattga tgtacttatt
    14941 cagaacgaag ataaacaaat tgagctttct gcggaaatgg atgttatgga acaaaagctc
    15001 aacacattaa aacggactct ggaaaagcga gagcaggatg caaagctggc cgaacaaaga
    15061 aaaaatgacg ttgttatgta cttggcgcac gatattaaaa cgccccttac atccattatc
    15121 ggttatttga gcctgcttga cgaggctcca gacatgccgg tagatcaaaa ggcaaagtat
    15181 gtgcatatca cgttggacaa agcgtatcga ctcgaacagc taatcgacga gttttttgag
    15241 attacacggt ataacctaca aacgataacg ctaacaaaaa cgcacataga cctatactat
    15301 atgctggtgc agatgaccga tgaattttat cctcagcttt ccgcacatgg aaaacaggcg
    15361 gttattcacg cccccgagga tctgaccgtg tccggcgacc ctgataaact cgcgagagtc
    15421 tttaacaaca ttttgaaaaa cgccgctgca tacagtgagg ataacagcat cattgacatt
    15481 accgcgggcc tctccgggga tgtggtgtca atcgaattca agaacactgg aagcatccca
    15541 aaagataagc tagctgccat atttgaaaag ttctataggc tggacaatgc tcgttcttcc
    15601 gatacgggtg gcgcgggact tggattggcg attgcaaaag aaattattgt tcagcatgga
    15661 gggcagattt acgcggaaag caatgataac tatacgacgt ttagggtaga gcttccagcg
    15721 atgccagact tggttgataa aagga
//
LOCUS       DAZKNV010000059        14815 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000059 DAZKNV010000000
VERSION     DAZKNV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.059"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(296..1024)
                     /locus_tag="ACG8M1_002184"
     CDS             complement(296..1024)
                     /locus_tag="ACG8M1_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422858.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="ACG8M1_002185"
     CDS             complement(1002..2576)
                     /locus_tag="ACG8M1_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0422859.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="ACG8M1_002186"
     CDS             2805..3743
                     /locus_tag="ACG8M1_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422860.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="ACG8M1_002187"
     CDS             3755..4666
                     /locus_tag="ACG8M1_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422861.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="ACG8M1_002188"
     CDS             4690..6162
                     /locus_tag="ACG8M1_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0422862.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="ACG8M1_002189"
     CDS             6213..6824
                     /locus_tag="ACG8M1_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0422863.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="ACG8M1_002190"
     CDS             6854..8767
                     /locus_tag="ACG8M1_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HFQ0422864.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="ACG8M1_002191"
     CDS             8895..11876
                     /locus_tag="ACG8M1_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFQ0422865.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="ACG8M1_002192"
     CDS             11873..13534
                     /locus_tag="ACG8M1_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein O-GlcNAcase"
                     /protein_id="HFQ0422866.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="ACG8M1_002193"
     CDS             13574..14506
                     /locus_tag="ACG8M1_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFQ0422867.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4815 a         2333 c         2978 g         4689 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DAZKNV010000060        14676 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000060 DAZKNV010000000
VERSION     DAZKNV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.060"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(718..3867)
                     /locus_tag="ACG8M1_002194"
     CDS             complement(718..3867)
                     /locus_tag="ACG8M1_002194"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFQ0422868.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYAQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3881..5125)
                     /locus_tag="ACG8M1_002195"
     CDS             complement(3881..5125)
                     /locus_tag="ACG8M1_002195"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFQ0422869.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5118..6710)
                     /locus_tag="ACG8M1_002196"
     CDS             complement(5118..6710)
                     /locus_tag="ACG8M1_002196"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFQ0422870.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7220..7945)
                     /locus_tag="ACG8M1_002197"
     CDS             complement(7220..7945)
                     /locus_tag="ACG8M1_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422871.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8099..8425)
                     /locus_tag="ACG8M1_002198"
     CDS             complement(8099..8425)
                     /locus_tag="ACG8M1_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422872.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8462..8827)
                     /locus_tag="ACG8M1_002199"
     CDS             complement(8462..8827)
                     /locus_tag="ACG8M1_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFQ0422873.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8864..9079)
                     /locus_tag="ACG8M1_002200"
     CDS             complement(8864..9079)
                     /locus_tag="ACG8M1_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0422874.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9208..9543
                     /locus_tag="ACG8M1_002201"
     CDS             9208..9543
                     /locus_tag="ACG8M1_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0422875.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9619..11616)
                     /locus_tag="ACG8M1_002202"
     CDS             complement(9619..11616)
                     /locus_tag="ACG8M1_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422876.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11714..11989)
                     /locus_tag="ACG8M1_002203"
     CDS             complement(11714..11989)
                     /locus_tag="ACG8M1_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422877.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12221..12955
                     /locus_tag="ACG8M1_002204"
     CDS             12221..12955
                     /locus_tag="ACG8M1_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0422878.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12994..14136
                     /locus_tag="ACG8M1_002205"
     CDS             12994..14136
                     /locus_tag="ACG8M1_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0422879.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         4555 a         2820 c         2226 g         5075 t
ORIGIN      
        1 ggactaatac aggtagtcct cttttttgtt attttgatat tctaaatcat tttttattgg
       61 attattccct tgttcgatat agacccaaat tgatctatca ataattatca aactgagtca
      121 tatagagaca aaaatttcaa aaatgacctg ttaaatggtc atcgaatatc atttaaaatc
      181 aatacgacgg agtcagacac ggagtcaaaa caagcccgct gagagtaaaa aatatataca
      241 gtcccatagg taaagtgcca caggactgta tattttttta tttgagatta cctgaaatga
      301 ttccatttac tttttatctc attttttcct actagttagt atcaaatact ctcctatttt
      361 ctcaataaac tattttgggt tacatggtat ctgaaacagc taaaaccttg tcattacagc
      421 aaaaaatcac tttatctccg tttcatttca gatacatttc acttaagcgg attccaaaaa
      481 aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt attggttcct ctcaaaacac
      541 ggtcatataa caacggggtg gggtaaatga atgaaaaagg tggaggaaac attattcaat
      601 agctgtctta aatacttcgt tataaaatgt gaacaaataa aagacatcta tccctatttt
      661 ctacacttcc actttactac catctttgaa tcgtacaatt ttcttaactc ttctcgttta
      721 cctcaattca ttttcaagtg gaatcagctc atcatctaac attttacgcc atgctcgctt
      781 catttcttgt gcgtatttaa atggcttcgc ttctggatgg ttggctttat atccttcgta
      841 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
      901 cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa agacatgaat
      961 caaatcatca ctcgcttgtg taaaatagcg acgtttaatg acaaagatat cttcattact
     1021 atctaaagtc cccacatcaa acgcatttaa aatttgtcgg taaacttctt tgactccttc
     1081 tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg aactattcgc
     1141 cgcataagtt cctagtaatt gatcaatata agtagaatca atatcataca acttcgtggt
     1201 attttcacta taaaattcga tcgtggaaaa atcttctccc tctttttctg gttcttcctc
     1261 tattaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa gttgaatttg
     1321 attgttcaag gttgaagatt tcaccatgtc atcattgtaa tcgtcataag tcactaacga
     1381 ttcataagca cgattcaatt cttggaatgc tttgacgtac tcgatacgga tttcaagtgg
     1441 cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat atgcttgctt
     1501 gaatcttttt ttggattcct gataacttgg ataaatcaaa cccgattctt cttttgcttc
     1561 tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtggctggct ttcggaaagt
     1621 aacaattagt ccttttgttt tttctggata cgtacggttc gtacgtgaaa aagcttggat
     1681 caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag gtgcgtcaaa
     1741 acctgtcaat agacgatcca ctacgatcac taaatcaatt tgtttcccaa attgtttgaa
     1801 ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct caatgtctgc
     1861 taatgaccag gaagtatcat aatactgatt atattcctca ataatttttt gcatttcttc
     1921 ttgttggaca cttgaatctc ggctgttttc ttctaatgaa taggtaatag cgattcgtgg
     1981 aaaatcagga tcctccatcg ttcttccttc acgaatgggc tgattaggaa actcttttgt
     2041 taaccagtca ggttctttcg tcatttcttt gatcgctcga taatactttt tggccatgtc
     2101 aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa aatcaaattt
     2161 tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat gttcatctgc
     2221 ttcaaaaaca gtagggtcca aataactttc ttttttgaca ggctccattt gatcaatcat
     2281 acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta atttccgata
     2341 gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt gaaatcctaa
     2401 aaccgagcca tcttctaatg cattcttgat ggtataggta tgcaagacct ctccatactg
     2461 atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag ggaaaatcgg
     2521 tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt cttccatatt
     2581 ttcagcactt aacgctcgat gacactcatc tactacaaac acgatatgtt gccccattaa
     2641 tttttggaag cgattggttc cttttttctc ttcttgtttt tttgcatatt tcaacgccgc
     2701 atctagcttt tgacgggttg taataatcac aacatttgca ttggcatctg ccaacagagt
     2761 ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt tggcgttccc
     2821 ggaagaaatc ccagtattaa attccgaagc aaatttcgta aactctgtgg tggtttgatt
     2881 atctaaatct ttgcggtcca ctaacatgat cgtccgatcg atccccgatt ttcgtgctaa
     2941 aagcttagta gatacaaaac tagtcaacgt ttttcctgaa ccagtcgcat gccacacata
     3001 tcctgattga tgtttatttg cagcaataaa caaggcttga atcgcatgta cttgataagg
     3061 atgtaacacc atgaggattt tattgtcttg atcttcactg acaatcgtat aatccgcaat
     3121 caagcgatga gcatccggga tatttagcac ttgtttgcaa aactcatata agttttctac
     3181 ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat cctttggtaa
     3241 ggcatttgca aaataccgag tggtttgttc attggaaacc acaaacaact gtaaggtcga
     3301 aaagatattg ttccgaaaca taccttcttc tgcatatttt ttgatttggt taaacgcctg
     3361 ataaaaacta tcttttgcgg ttacttgttt cagctcgatt tggacaatcg gtaatccatt
     3421 gatcagtaag gtgacgtcaa aacgtcgatc ccgtgcttct atgttacttc cacgttttgc
     3481 aatttgatgg accacttcat aggtagagat tcctccacca atgtcttgat tagaataaag
     3541 aatgagcgag acagaaccca gttgcggatc ttcccgttca atcgtgatcc gagccattcc
     3601 attttcacct tttaaccatt tcgcagcatc aaagggggtt ttcgttcgta gtaacaattc
     3661 tgttttgatc gtttcaaatt ctttatcggt caaaggaaaa tcattcagtt ctgcttgatt
     3721 atttgagatg attttttggc gtaaattgac ccaaagatct tcttctgatt ttagatcggg
     3781 acgatacgtc cactgattat gcccttcccc caatacacgg atcaactgtt cttcgacttc
     3841 cgcttcctca cggtgactaa ttttcattta tcttccctcc ctaaacaaac atcttttgta
     3901 agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga gcgatcgtgt
     3961 cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc ctagtaaaag
     4021 gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt ccttcagtgt
     4081 tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg aactcattat
     4141 ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc gtcataccaa
     4201 gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg aattcatttg
     4261 gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca tcaaactgtt
     4321 ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag tctaaatctt
     4381 tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt tcccaatctt
     4441 ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg aacatttttt
     4501 gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga agagcgatag
     4561 tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat attggaaatt
     4621 gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct gaacctggat
     4681 tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata aaatattctg
     4741 aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat acacccggtt
     4801 ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc atgataaaat
     4861 cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta attttatatc
     4921 ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa ttgctattag
     4981 atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact ccatcttttt
     5041 tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct gggaaacgaa
     5101 tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg taaccacgct
     5161 tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt ttctagcact
     5221 tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc aattggttct
     5281 tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt ttctttgatt
     5341 tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc ataggtttcg
     5401 aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt gacaaattct
     5461 cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa tacaatcacc
     5521 gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac agcataaata
     5581 ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg gaataaaact
     5641 ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa accatgaaga
     5701 agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt aaaccgagaa
     5761 tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt cattactact
     5821 gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc cccattgcgg
     5881 agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc tagattgtat
     5941 gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt taagtagtta
     6001 cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact aaagaatcgt
     6061 cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat atgaggcgtg
     6121 taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag aaattcataa
     6181 gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa tttcttaatg
     6241 acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt tgattggaga
     6301 tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg cacaaaggct
     6361 ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa gacgttgaaa
     6421 agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat cagatcttct
     6481 tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct taccgtatca
     6541 tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg gtcggataaa
     6601 tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc cattttgcta
     6661 cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa aaagatacac
     6721 tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc ccttttagaa
     6781 aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga aaggagtcta
     6841 acgttgtttg atataactta gactgatcgt taacttattt tttatatttc tacatagtta
     6901 tctttagaac catttcagat acatatgaaa caattacata tgattttttc ataaaaaaac
     6961 agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac taaaatcact
     7021 acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct ccgtttcatt
     7081 tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc cagtagctta
     7141 tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg gtaaataaat
     7201 gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg taatcagtta
     7261 cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt aaccgaagtg
     7321 gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga ttagctaata
     7381 aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc gtgattcctt
     7441 tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct acaaatgaat
     7501 taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct gtatatatgg
     7561 cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca ttagttagta
     7621 aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc ctaacagctt
     7681 taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct tccataaacc
     7741 ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct ttcatttctg
     7801 agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc tgattcgttt
     7861 ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt gccaaacaaa
     7921 tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat aacagtgact
     7981 aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca aaaaaactcc
     8041 ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata catttaaatc
     8101 aatttaacat taacacctca gtatatggta tctctacata tacacggtct ttttttggat
     8161 agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta gcccggtacg
     8221 tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt aagttatact
     8281 gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca gatgaacccg
     8341 tcattcttga aaaaattata cctataatag ccaatacaac gatacctata atgacaaact
     8401 tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg attttctctc
     8461 atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct acccctgcta
     8521 tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc ataataacag
     8581 caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa atccaaccaa
     8641 taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc atttcattaa
     8701 ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct gtttcttgta
     8761 atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca cattttctac
     8821 aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg tttactttat
     8881 taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa agcattttca
     8941 tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat tgctgtgtaa
     9001 cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg tatcggctga
     9061 gattacttac ttttttcatg attctcccct tctgttttat tatatacaac aatatgatgt
     9121 atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa caacttgttg
     9181 tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa ggtcattaga
     9241 gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat cttctctaca
     9301 caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga tagcttaaca
     9361 gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt tgacatagat
     9421 tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc aattcgaaca
     9481 attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct attgaaagat
     9541 tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa ataagattaa
     9601 gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc ttactctccg
     9661 tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa ctcctgataa
     9721 tatcaattct tttattactt catctatccc tgcccctttc gctagatata ctaaaaaact
     9781 actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt caagagtgaa
     9841 tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc tgttatccct
     9901 gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca ttagatatgt
     9961 cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca attgtttttc
    10021 cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt tttcgttaaa
    10081 acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt tttccagaag
    10141 tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa cgtctaatcg
    10201 atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct ttaacctatt
    10261 taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta tcaatcctat
    10321 aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt taccatagta
    10381 agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac tttccttact
    10441 atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca tttcctctag
    10501 ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt caaaaagtac
    10561 ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt tctctaatag
    10621 ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa ctccaataaa
    10681 attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc cagttttact
    10741 ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta agtttttact
    10801 tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct cattaaaaga
    10861 catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt ctttgtcgtc
    10921 attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc tccctgaatc
    10981 actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag taatatctaa
    11041 catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa aaaacattct
    11101 attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt attcgtaaac
    11161 agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa tcttgtattt
    11221 ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat tatgaactaa
    11281 attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac tcaaatctac
    11341 taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta ctctggtttc
    11401 cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa atgattgtga
    11461 tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat ctaaacacct
    11521 atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt tttctttatc
    11581 tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct tataaaattc
    11641 tgttaaagac taaaacatac agataataaa aacaaactct ttattactat atgttttagt
    11701 cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca gattttttaa
    11761 atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca tattttctaa
    11821 tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata tactctagag
    11881 tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc tctttcactt
    11941 gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata tttccccctc
    12001 ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt gctcaaaata
    12061 aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt catcgacata
    12121 cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat ttacaacacc
    12181 ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac gtccaccaat
    12241 aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa gaaagagtaa
    12301 aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa ttgacaaaaa
    12361 gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat tatcccgaat
    12421 tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag aagaatatat
    12481 tttgggaatt attctttata gagatagcat tgtactagat ggtataacat ttccagataa
    12541 aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt tagatacatg
    12601 gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta acaagacttg
    12661 taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag aagaattatt
    12721 catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta gcagtataga
    12781 agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag acatgtctta
    12841 tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac aaacgatttc
    12901 atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca tctagtggta
    12961 agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa gtacaaaaag
    13021 aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc acgaactggt
    13081 gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca aaaagattat
    13141 gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga tatgacattt
    13201 gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc ttcaacaatc
    13261 gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa gcttaaacta
    13321 tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag taaatatgaa
    13381 agttacgatt atatgagaaa acagactgca caaattttac gctacggggt tgcaatgcaa
    13441 tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga gtatgagaaa
    13501 aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt taaagatttt
    13561 ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat gagaaagagt
    13621 gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact acatgtcaat
    13681 aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa aacaagagct
    13741 tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa ctggaaatta
    13801 cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga gcaacatgtt
    13861 tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg gttaagatat
    13921 attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca tacacatgct
    13981 agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt agggcatgaa
    14041 aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc taagaaaaca
    14101 ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa atctggtcat
    14161 ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg ttctagctcc
    14221 tataacaggt ttacccaaca ctgccttcca atgactcttt tgggaatcag aggaaagaat
    14281 caggctttat agagatattt catctaacaa attactttag actgacagta tatatcagca
    14341 ggtactgtca tcgggaacgt agccaatatc gtatccaaaa cagcaggtag agaagctatt
    14401 tgaggattca agttattcta tttcaaccat gaagttaagt tcattaaaaa taaagatagt
    14461 tggtatttca ataatttttg tatagagtta atcactttat tgatgctaat tcatcttgat
    14521 tggtattata atcgtattca agttgcgtgg cgtgcttttg ctagaaaata tataactgtt
    14581 ctttataaag aaatataagg attaaacatt ttttatcata gagttttact tatctataga
    14641 attatgtctg ttcctaattc agtttgatga attaac
//
LOCUS       DAZKNV010000061        13969 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000061 DAZKNV010000000
VERSION     DAZKNV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.061"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACG8M1_002206"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACG8M1_002206"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFQ0422880.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="ACG8M1_002207"
     CDS             complement(2424..2675)
                     /locus_tag="ACG8M1_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFQ0422881.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="ACG8M1_002208"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="ACG8M1_002208"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFQ0422882.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="ACG8M1_002209"
     CDS             3624..3842
                     /locus_tag="ACG8M1_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422883.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="ACG8M1_002210"
     CDS             complement(4130..4642)
                     /locus_tag="ACG8M1_002210"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFQ0422884.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="ACG8M1_002211"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="ACG8M1_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFQ0422885.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLANEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7538)
                     /locus_tag="ACG8M1_002212"
     CDS             complement(7095..7538)
                     /locus_tag="ACG8M1_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFQ0422886.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="ACG8M1_002213"
     CDS             complement(7539..8327)
                     /locus_tag="ACG8M1_002213"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0422887.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /gene="rnz"
                     /locus_tag="ACG8M1_002214"
     CDS             complement(8324..9265)
                     /gene="rnz"
                     /locus_tag="ACG8M1_002214"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFQ0422888.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="ACG8M1_002215"
     CDS             complement(9442..10029)
                     /locus_tag="ACG8M1_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFQ0422889.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="ACG8M1_002216"
     CDS             complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="ACG8M1_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFQ0422890.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="ACG8M1_002217"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="ACG8M1_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFQ0422891.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="ACG8M1_002218"
     CDS             complement(12946..13881)
                     /locus_tag="ACG8M1_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0422892.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3856 a         3131 c         2454 g         4528 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttgcca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttgggatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DAZKNV010000062        13917 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000062 DAZKNV010000000
VERSION     DAZKNV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.062"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..505
                     /locus_tag="ACG8M1_002219"
     CDS             131..505
                     /locus_tag="ACG8M1_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0422893.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACG8M1_002220"
     CDS             complement(619..1248)
                     /locus_tag="ACG8M1_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0422894.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACG8M1_002221"
     tRNA            complement(1382..1454)
                     /locus_tag="ACG8M1_002221"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="ACG8M1_002222"
     tRNA            1668..1741
                     /locus_tag="ACG8M1_002222"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="ACG8M1_002223"
     CDS             complement(1879..2043)
                     /locus_tag="ACG8M1_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422895.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="ACG8M1_002224"
     CDS             2338..3666
                     /locus_tag="ACG8M1_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFQ0422896.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="ACG8M1_002225"
     CDS             3868..4701
                     /locus_tag="ACG8M1_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFQ0422897.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="ACG8M1_002226"
     CDS             4717..5454
                     /locus_tag="ACG8M1_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFQ0422898.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="ACG8M1_002227"
     CDS             complement(5609..6577)
                     /locus_tag="ACG8M1_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFQ0422899.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="ACG8M1_002228"
     CDS             6809..7642
                     /locus_tag="ACG8M1_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFQ0422900.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="ACG8M1_002229"
     CDS             7676..8515
                     /locus_tag="ACG8M1_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0422901.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="ACG8M1_002230"
     CDS             8541..9101
                     /locus_tag="ACG8M1_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0422902.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="ACG8M1_002231"
     CDS             9300..11021
                     /locus_tag="ACG8M1_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFQ0422903.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="ACG8M1_002232"
     CDS             11186..12328
                     /locus_tag="ACG8M1_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFQ0422904.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="ACG8M1_002233"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="ACG8M1_002233"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFQ0422905.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4750 a         2298 c         2834 g         4035 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattggat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DAZKNV010000063        13810 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000063 DAZKNV010000000
VERSION     DAZKNV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.064"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(221..1423)
                     /locus_tag="ACG8M1_002234"
     CDS             complement(221..1423)
                     /locus_tag="ACG8M1_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0422906.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1426..1620)
                     /locus_tag="ACG8M1_002235"
     CDS             complement(1426..1620)
                     /locus_tag="ACG8M1_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFQ0422907.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1667..2515)
                     /locus_tag="ACG8M1_002236"
     CDS             complement(1667..2515)
                     /locus_tag="ACG8M1_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HFQ0422908.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2720..3070)
                     /locus_tag="ACG8M1_002237"
     CDS             complement(2720..3070)
                     /locus_tag="ACG8M1_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422909.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3248..4111
                     /locus_tag="ACG8M1_002238"
     CDS             3248..4111
                     /locus_tag="ACG8M1_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0422910.1"
                     /translation="MFGLVQPNKVKVGQRIKEIKDGMSLSFTELGNRLGLKKPTISSY
                     VQGYALAPKSVINQLSSISGKPVGWFYFGHVEEYIREYLFLIGQKKIVDDYPEIIEKI
                     KQEFYTGEFKNPAWENELGYPLEEFIQECFVEYSSEIMKDYVVQITKEVLEESKTLNK
                     LSSKAKEEAVTILSSGIIDYIEMSGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSY
                     LIGKLINILGTDEDTELFLSSLSMIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREK
                     TPDEFYDWFEK"
     gene            4735..5727
                     /locus_tag="ACG8M1_002239"
     CDS             4735..5727
                     /locus_tag="ACG8M1_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0422911.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5743..6627
                     /locus_tag="ACG8M1_002240"
     CDS             5743..6627
                     /locus_tag="ACG8M1_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0422912.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6676..8283
                     /locus_tag="ACG8M1_002241"
     CDS             6676..8283
                     /locus_tag="ACG8M1_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0422913.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8284..9768
                     /locus_tag="ACG8M1_002242"
     CDS             8284..9768
                     /locus_tag="ACG8M1_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFQ0422914.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9945..10937
                     /locus_tag="ACG8M1_002243"
     CDS             9945..10937
                     /locus_tag="ACG8M1_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0422915.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10989..11858
                     /locus_tag="ACG8M1_002244"
     CDS             10989..11858
                     /locus_tag="ACG8M1_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005472675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0422916.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12278..>13810)
                     /gene="guaA"
                     /locus_tag="ACG8M1_002245"
     CDS             complement(12278..>13810)
                     /gene="guaA"
                     /locus_tag="ACG8M1_002245"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFQ0422917.1"
                     /translation="KIIVLDYGSQYNQLITRRIREFGVFSELMSHRITAEEVKAMNPK
                     GIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGK
                     AELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKM
                     YGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLG
                     LSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAK
                     ERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGT
                     ETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPG
                     LGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRT
                     YDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVE
                     WE"
BASE COUNT         4231 a         2337 c         2851 g         4391 t
ORIGIN      
        1 acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag taaggtactg
       61 ttctatgggg cgcttacgtt gaaaaacgtt gatttatcgg cattccccat ccatattata
      121 tttacgtctt attcccactc aatatgagta gcctcgtaaa gaagctatta tatcagtgct
      181 ttttcagcct attcctcatt ttggtaggga aatggtaggg ttagattttt actgcttgat
      241 ttccattaaa gtttgcaact ttagattttg ttgcacaggt aaatttaatg tttcctgtca
      301 tttgttctgc aattccttca tcattacggc tccatagatg agcgtagtgc tttaaagtga
      361 tttcagggct agaatggcct aaccgttgcg acacgaccag aatgtctgcg ttaaactcat
      421 tgattaggta gctaacatga gaatgacgta atccttttcc ttgtattagg ggtaccttag
      481 ctagtttggc ataacgctga ataattcgtt gaacagttga acgatagagt gggaggtcag
      541 tgtagctaag aataaattgt tctacaccat gatttttttg aataactttc cactttttta
      601 gcacttcaat tgtatcatcg tccagagaaa tgatccgcaa gccgctttca gtttttgtgt
      661 aaggtttccg aataaaatct ttttgatttg tcatttccaa ggtgtgatga accctcaact
      721 ttttacgttt gaagtccacg tcattccaat taagtgctaa tccttcgctt acacgaacac
      781 cagtcatgta atatagccag atcattaaaa aacacatatg ttcgtagaaa tcatctttat
      841 aaatttttgc caaaacttct tcaaattctt cttttgtcca gtaaggaacg attgattttc
      901 cttttggaat tgcttttgtt cttttggaaa tattctcatt cagaaattgc agggtgaccg
      961 catagtctaa tgatttacga aacataccgt acataagtga actgtatgct tgtgagtatc
     1021 cgctatcgtt caataaccaa attcgataat tttcacaatc tcgcacattg atttcacgaa
     1081 gcttcttatc accgaaaaat tcagtaatct gaatcaatcc acactcacga gaactccaag
     1141 tacttttttg tacgctagct ttgtagtgtg gaacgtaaga ctgctccata aattctttgt
     1201 aagttaaatc ataattcgca aatccattta caaccatgta ttcatttttt atacgcatga
     1261 cttctttgtg tgcttcacga gctgatgaga atcgttttcc tagagaatct tttgttcctt
     1321 tcttctggat cctctttcca gtcacttgat ctgttcctaa ctcaactaga taagaaaagc
     1381 gaccattttt atcttgatac acacaagggt attttgtttt catagttatt cctcctgtga
     1441 aagaggaaca cctataattt cttcaattac ttgtcggggt actaccccaa ctcttttatt
     1501 attataatat ggatatccct gatttaccat tcttgttttt gcttgtcgga ttattgtggt
     1561 agcttgatgt gttttaaatc ctagagcctc taaatctttt cgacaaattg tatttttcat
     1621 tgtataaact cactttcaaa gaaaacacta tcattgggta atagtgttat ttctttattt
     1681 ttgtataatg aacggtactt tcttgaaaat ccatcacttg ttcaggactt cccaactcat
     1741 ttaaagctaa agcattgtaa aaaaatggac gtctaactat atattcgctt gtatatagta
     1801 tatcttgatt cgtggaatca tagggtttct ttaccatctt tttggtgaca gttggtagtt
     1861 tgagattccg ggacttgaaa aaagcttttt tcttatgctc tttcaattcc agctctttat
     1921 cgaaatattt gctgatatag cgcccgcgat tttcgatact gtctacatcg atcttgttga
     1981 tcttaacgaa accctgaccc caaatcgtag ttaaccggtt aaatgagata aaggggaaat
     2041 caaacaagat aatatggtag tggattgcac cgcgttgctg cttttcccac gtggcgagat
     2101 actttaaatt tgctttttta gttttataga ggtcataatt cagtcgtttg ataaattttt
     2161 taaattcatt atttgcatac tcaatgtctt gaatgttttc tttgaaagtg agagttaaaa
     2221 atttcgtttg attgtcaaaa ttcgtgtcta caaggcgggc aatctcaaat cgcatacttt
     2281 gataatgttt ctgtttgcgt tttaaactgt catattgtcc ttgagcggat aattcatcat
     2341 agttttttct tttttcaaga gtaatatcat tttcataaat ccaagctaat ttttgttttc
     2401 gttccagatt tacttcgttt tcgatcgttt tacgtttggg agtaatgatt gcttcataat
     2461 cataaatttc aatatacgtg ggagtttcaa tgattttctg attataagct tgcaaaaatc
     2521 atcactcctt gttgcgtatt cgattgtcaa agaaccagtc attttctcct gatgttgatc
     2581 tataaatcaa gttaaggggg aaggcctgcg tagcagccct tctagcctat ggggtgttgg
     2641 gcggtcttaa cggacagaaa cggctctgtg ggcgctgccc cgccgtttcg tcctaaccac
     2701 ccaacactcc atagtatagt tagttttgtg tagtggtacc ttgttttctg ggaatcaaag
     2761 ttgccgtatc agcggttgcc gataacccat aactgacaaa ttgtccattc gagcgtcccc
     2821 aaggtacaat caccaaattg gtaaatgtaa ttatggctaa accttgttgg gtaagttctt
     2881 ccggcgtgat cacaggatgt tcagatttga ctttgacact gattttttcg tagcgaagtt
     2941 ttggtaggat acattcgtag ctccaaccta gaatttcgcc ctccttttgc cagcgagtga
     3001 cattgacgac ttggtattct ttttcgagtg tttcttttgg taaactgaga tcggtaattt
     3061 ttattggcat cacaattctc cttttttata cgaaagttta tacgatttga ttaaaaaata
     3121 tagatggcca tctacgactt gtattatata cgagaactta tacgtagtca agagattttc
     3181 taaaaaaata tatacgattt tttatacgag tgttataatg aaaaaaatga taaggaggaa
     3241 tttgaatatg tttggtttag tacaacctaa taaagtgaag gtgggccaac gaatcaaaga
     3301 aataaaagac ggaatgtctc tctcttttac agaattaggg aatcgattag gtttaaaaaa
     3361 gccgacgatc agttcctacg ttcaaggcta tgcgttggct cctaagagtg tgatcaacca
     3421 attatctagt atcagcggaa aacctgtcgg ctggttttat tttgggcatg tggaagaata
     3481 tatccgagag tatttgtttc tcattggtca gaaaaaaata gtggacgatt atcctgaaat
     3541 cattgagaaa ataaagcaag aattttatac gggcgagttc aaaaatcctg cttgggagaa
     3601 tgagctaggc tatcctttgg aggaatttat ccaagaatgt tttgtagaat attcgagtga
     3661 aatcatgaag gactatgtcg tacagattac gaaagaggta cttgaagaat ccaaaacgct
     3721 aaacaaacta tcatcaaaag caaaagaaga agctgtcacg attctttcat ctgggatcat
     3781 tgactatatc gagatgagtg gtgagatcaa gtatggagag aaagatcgca ttgcgaaaat
     3841 ggtgaaagaa tcaataaaaa cctttgatgt gaaacaagac ctgacattta atgattccta
     3901 tttgattgga aagttgatca atattcttgg tacagatgaa gatacggagc tgtttctttc
     3961 ttctttatca atgatattta ctgataagca tttttccact cgatttggtg gggaagaatt
     4021 agtcgaaata tttcaatcga tgcgaccagc gttaatcaaa ctctatcggg agaaaacacc
     4081 agatgaattt tatgattggt ttgagaagta aaataagaaa agtggcttag attacaagtt
     4141 ggtgaaaaaa tttttttcag cataacatca gtaatctata aaggggttgt tgattatact
     4201 gtagaagtta agtactcaag agattttttg tacgtaaaca aagcaaaaaa gggtgcagtt
     4261 tcactagaaa atgtactctt ttttgtgatt tttcttagtt atagagtttt tttgaaactt
     4321 taaaaatgag aaaacatatt gattttaaag agtgtagaca tagcttcttt tgctaaatag
     4381 attaaactta ctggtgagtg gtcttgaaca tacttttaaa tcacatttta ctgagtttta
     4441 ttggatttta taattcattg gaaacctcgt acttaatctg tttttatcta tcgactagaa
     4501 tctgtatata ttccagctat caatgaggcc gcagaaaagg gtgcttaaaa ataatctgtt
     4561 gtttaaaata ttattatcag aatacttaga tacaaaattc tggcacaaag taaaaaaaat
     4621 attgacttaa aaaaatggat atggtaatct ataaacgaaa atagtggtaa cgtttccaaa
     4681 atgcatcttc gttaaatttt tattttttta aacgaaaatg gaaacgtttc taaaatgtat
     4741 tgggaggaga ttgaattgga aaagacattg ggaccaggtg gtgagataag ggcggtacaa
     4801 cgggataaaa aaaatatttc gaagtgggaa aaattaaaga aacagttgcg gcgtgataag
     4861 tggatgtact tgttgctctt accaggtatc atcatgacgt ttatctttaa gtatgtgcca
     4921 atgtacggtg ctgtgattgc atttaaagac tataatccta tgctaggaat tttggaaagt
     4981 ccttgggtag gactagatca ctttagggaa tttatcagtt caccaaattt tacgcttttg
     5041 ctgagcaaca cattaaaaat tagtatttat ggtttattgt taggtttttt tccaccaatt
     5101 attttagcac tgagcttgaa tcaaattatc aataaaaaaa taaaacagaa aatccagttg
     5161 attctatatg cgccgaattt tatctcagta gttattattg tggggatgct gtttttgttc
     5221 ctatccgcaa atggacctat taatgggtta gtagaaaagg ttacggggca accaattatg
     5281 ttcatgtcta atccagctta tttcagaacg atttatattt tatcgggaat ttggcaagga
     5341 atcggctggt catccattct ttacaccgca acgctggcgg gagtcagtac cgatttatat
     5401 gaggcagcaa atatcgatgg ggcaaatatt ttacaaaaga tttggcatat cgatttgcct
     5461 gcattgaggc ctgtgatggt gatcagcttc atcttggccg ccggcggtat tatgaatgta
     5521 ggatatgaaa aagcctactt gatgcaaact tcaatgaaca tccctgcctc agaaatcatt
     5581 tccacttatg tatacaaagt cggcttgcaa tcaggtgatt atgcctactc tgctgctgtt
     5641 ggtctgttca atatgattat taatgtcgtt ttattactga ttgtcaacaa tataaccaag
     5701 cggctaaacg atggtcaagg cttgtaatga aaggagaaaa ttatgaatag tgctttatca
     5761 aaaatcgacc gtcaaatctt atggttgaat cgagtgattg taactttttt agtcgtcatc
     5821 accattgttc cgctgattta tgtactggta gcttctttta tggacccagc tactttgatc
     5881 aataaaggta taagcttcaa tccgaaagat tggacaatac agggatatca acgggtattt
     5941 gcagatgatt ccattttacg cggttttgta aattcgttgt tttactcttt tagcttcagc
     6001 ttattgactg tatttattac gatgatcact gcgtatcctt tgtctcgacc taacttggcg
     6061 gggaaaaaga ttattatgac tttttttgtc attacaatgt tcgtgggtgg tggcttgata
     6121 cctacctatt tattggtaaa gaacttgggc atgttagata gtgtatgggc gattatcgta
     6181 ccaggtgcta taaatgtgtg gaatattatc ttagcccgta cctattttag tgctttgcca
     6241 aaagaacttt ctgaagctgc tactatcgat ggcgccaatg acttgcaaat actgttcaaa
     6301 gtcatgcttc cattagcgaa accaattatg ttcgtattgt ttttatatgc ctttgttggg
     6361 caatggaact catactttga tgccatgatt tacatcaaag atcccgactt acagccgttg
     6421 caactcgtat taagaaatat tttgatccaa aaccaacctt cacaagacat ggtgggagcc
     6481 aatactgcca tggcagaaat gaaacaaatt gctgagttga tcaaatacgc aacgatcgtc
     6541 atttctagtc tgccattaat cataatgtat cctttcttcc aaaaatattt tgataaaggt
     6601 gttttagttg gttctgttaa agggtaagta ttgttcacta tttgtatgaa taaaaattat
     6661 aaaggagatt ttaagatgaa agcaaaatgg atgctgccaa tcgtttttac ttccgtacta
     6721 attttggggg cttgtggagg ctcaaaagaa aagagtaaat caagccctga ttatgaacta
     6781 gaaaatgtct cttttccatt gaaagaaaaa gtatctttaa aaatgatgtc tcaaagtgcc
     6841 cctttggctc ccaatgatcc taatgacaaa ttgattttcc aacgattaga agaagagacc
     6901 aatctccata ttgattggac aaactacagt agtgattttg ccgaaaaaag aaatttggat
     6961 atcgctagtg gtgatttacc agatgccatc ttcaacgccg ctgcaggtga ctatgattta
     7021 ttaaactggg cggaaagtgg cgttattgta ccgattgaag atttgatcga agattatatg
     7081 ccaaatctga agaaaatttt tgatgaaaac cccgaatacc gacaaatgtc tactgcacct
     7141 gatggtcaca tttactctat gccttggatt gaagaattag gcgaaggaaa agagtcgatt
     7201 catacagtaa atgggatggc ttggatcaac aaggagtggt tggataattt gggtcttgaa
     7261 atgccgcaaa ccactgatca gttgatgact gtgttggagg ctttcaagac gcaagatcca
     7321 aatggtaatg gtgaagcaga tgaaattcct tttagcttta ttaacaatgg aggaaacgaa
     7381 gacttaaaat ttttaatggg ggcattcggt ctaggtgata atgatgacca cttagtcgtt
     7441 gataacgatg gtcaggtaca atttactgct aacaaagaag ggtataaaga agccatcaaa
     7501 tatttcaatg aaatgaataa taaaggtctt attgataaag aggctttcga acaagattgg
     7561 aatacgtatg ttgccaaagg gaaagaacat aagtatggcg tgtactttac ttgggataaa
     7621 gcaaatatca cgggtgcaga tgatagttat gacgtcttgc cagtcttagc gggaccagat
     7681 ggaacgaaac atgttactcg tacgaatggc atgggtttct caagagatcg tttcgtaatt
     7741 actagtgcga ataaaaactt ggaacttaca gctaggtgga tagataaaat gtatgaaccg
     7801 ttacagtctg tccaaaataa ctggggaacc tacggtgatg aagcacaggc gaatattttt
     7861 gaattaaagg atggtatgtt aaaacatttg cctttagagg ggacagcacc gggggaacta
     7921 agacaaaaaa ccgaagctgg aggaccatta gcagttcttg attcttatta cggcacagtc
     7981 actactatgc cagatgatgc gaagtggcgt ttagatttga tgcatgacac gtatttgcca
     8041 tatattacag aagacaatat ctatccacgt gtctttttag aaaaagaaga aacagatcga
     8101 ttagcaaaaa tcgaaacgga tatgtgggat tacatctatc gcaaaagagc agagtggatc
     8161 accggcggta aaatcgatga agaatgggaa gaataccttg ctgaattgga acgtgtaggt
     8221 ttggaagaat ggattcaaat aaaacaaact ggctatgata attttttgaa gggagcacaa
     8281 taagtgttag tagaagaaac ggcgattttg gataaagcaa atcgatttat tgaaatgatg
     8341 cgaggaaaag ttaaccctca gtatcgacaa aactatcatt tttccgcacc catcgggtgg
     8401 ataaatgacc ccaatgggtt tatatattac aaagggcatt accatctctt ctatcaatac
     8461 tatccttacg atagtcgatg ggggcccatg cattgggggc atgcgcgcag tagtgatttg
     8521 gtccattggg aagatctacc agtagcgtta gccccagatc aaccttatga cagcggcggg
     8581 tgtttctcag gaagtgcaat tgaaagagac ggaaaactat atttatttta tacaggctgt
     8641 caagaaattg atggtattag ccatcagcat caatgtttgg cggtctctga agatggtatt
     8701 cattttagca aatacagtgg taatcctgtg gtagcagaaa aacagctagg tgaaaatggg
     8761 ctaatacaag aatttcgtga tcctaaagta attgttcaca acgatggtta ctatatggta
     8821 gtagctacta aatctacaca gtctactggt agaatagtga tgtttcaatc gtcagatttg
     8881 tatacttggc acttttactc tgtgctgcta gaagggactt cagagcaagg aataatgtgg
     8941 gaatgtcctg atttattcca tttagacgga cgagatgtct taatcatgtc tccgatacaa
     9001 atcaagaaga acggactgga atatcataat atcagttcta ccatggcttg tattggtgag
     9061 gtaaactggg aaacaggtca gatgatagtt gataatttcc atgaaatgga ttttggaatg
     9121 gatttttatg caccacaaac aacaagagat cctaatggtg gacgggtgat gattgcttgg
     9181 atgcagatgt gggatcgtac attgcctaca catgagttag gccatctttg ggcaggctct
     9241 atgagtttgc cccgagagtt aagagtgaaa aaaaatcgat tggtacaaaa acccatctca
     9301 actgtatata gtcatttagt ttatcaacaa ggcagtgaaa atattgcagt gactgacaca
     9361 tcagtcgtat ttcgaaacgc gctgtctgat tcttcatatt tacatctagt cgcagatttg
     9421 gagaaagctg aagtttttac aattgaatta ctgcggtcta agacggattg tctcaaacta
     9481 gcctatgaca ctgctacaca ggtttttgaa ttggatcgtc agaaactagg aagagagctt
     9541 acaggggcgg aagaagaccc tctgaatgta cgaaaagttg aagtaccttt gattgataat
     9601 cagctcgttc ttgagatttt tagagatacc tcatcaattg aagtctttat taatgggtta
     9661 gaagttatga cggctacttt ctatgagctg gaaaaagctc gagatatctt gtttcattcg
     9721 atcggagaaa gtcgtattca agcttttgaa acagcgagtg tgaaataaat gtttgattgc
     9781 ttaggcgatg aatcaattat ttaataggtt ttgaaggata atgtttttag aaaagaacag
     9841 atagctagat ttcccatgga tttgctatta gtattttgaa aaaattagta atttatgaca
     9901 aaattcatta tactaaactt gtgcagaaat gtgagggatc aactatgaaa gcaacaatga
     9961 aagatgtcgc aaaattagca ggtgttggag taggaactgt ttcccgggta ttgaataacg
    10021 gttctgttaa agcttctact agagaaaaag ttgaagcagc aatgacagag ttaaactatc
    10081 aaccagattt ttatgcccgg gggttaaaga tgaagcatac gaacacggtt gctttgattc
    10141 tacccacggt atggcatcca ttttttggcg aatttgccta ccatgtagaa acagcattag
    10201 aaagacaaaa ctacaagctt tatttgtgta actccagtgg taatagtgaa aaagaacaag
    10261 aatatatcca gatggtcagc caaaataaag tagacggcat cattggaatt acttattcag
    10321 atatcgatga atacatttcg agtaatctgc cttttgttag tattgaccgt tatttcactg
    10381 aagaggtgat ttatgtgacc gctgacaatg cggccggtgg acgtttggct gcaaatgaac
    10441 tttatcgccg aggatgtcag aatgtagcat atatcggtgg gtaccaagaa acaccgaatg
    10501 aaacgaagag tcgtcgaaaa tattttgaaa tcgagtgccg tcaactgggg atttcctata
    10561 aagcgttaga tatgttagaa cctttagacc atctctcaga acgtgtaaca aattttttgt
    10621 tagagaatcc cgatatcgat gggattttta cgatcaacga tccaatggca ttagctgtca
    10681 ttgatatgct tgaaaaaata gggaaaaacg taccagagga tgtccaagtt atcggatttg
    10741 atggtcaaaa gatgacagaa ggagatcctt atctagtctc aacgattgcc caacctacaa
    10801 agcaaatggc ggaagtggca gtggcaaaat taattgctgt cattaatgga gagacagtag
    10861 aaaaacgtac cgtattgccg attgaatttg gcgaaggtga cacaacgaaa cctttagtga
    10921 gaaacgattt tgcttagtgc aaatacgttt ctttttttga aaatgagtga atgaaaggtg
    10981 tagataaaat gttatatggt ggaatagaag ccggtggaac aaagtttgtc tgtgggattg
    11041 gtaatgaaca attacaagtg atagaacgga aaagttttcc taccacaaca ccagaagaaa
    11101 cgatggagca agtgtttgat ttctttgata agtacaaagg aaatatcgca tcaattggtg
    11161 taggagcatt tgggcctatt gatattcaaa tcgaatcaag aacttacgga tatatcacca
    11221 acacaccgaa gttagcttgg caaaattatc attttgtagg agctttggaa aacgccttgt
    11281 cggttcccat ctattggact accgatgtaa atgctgcttg ttatggagaa tatatggcag
    11341 ggtatggaaa aggtaaaaat agtgttctgt attacaccgt tggtacaggt gttggtggtg
    11401 gtgctgtagt ggatgggaaa atagtcgcag gttttagtca tcctgaaatg ggacatatgc
    11461 tcttacaacg tcataatgaa gatcaatttg aaggaatctg tccttttcat catgattgtt
    11521 tggaagggtt agcatcagga cctgcgattg aaaaacgctt tggaagaaaa gcccagacta
    11581 tctcatttga tcatccttat tggacgattg aggcagatta tcttgctcag tgtgtgtata
    11641 acacaacgtt actatatgca ccggaagtaa taattttagg cgggggtgta atgaaacagc
    11701 cgcaactact cgagttgatt cgccaatcgt ttaaagaaaa aatgggttcc tacgtggata
    11761 cgcctactct cgaagaatat ctactaactc caaggcttgc tgacaatgcg ggcttgattg
    11821 gctgcctagc tttagcaata aagaaactca atcattagaa tagtatttat tagaactatt
    11881 cataacatac cggaagttta aaagggtatt ctgaaactta aatagtctca attcattctt
    11941 ctttcttgag aatctgagta gagactttta ttctgtttca aattaatata attacgaaat
    12001 gatattgagt acaagaaagt tctttttacc agatctttta aatcgaaaaa tctgatatat
    12061 atatttatag tactaaaaat ctgattagat aaaaagctaa ttcaatagga aaataaaggt
    12121 agtgaataaa agcaaagccc ttgttagtag ttaatctaac aagggctttg gtagggaaaa
    12181 tggtaggaaa ccatcttatt ttttacgaaa atcaggaact ttagtaattg aataatgttg
    12241 atttataggt attcctcatc catattatgt tggctcttta ttcccactcc actgttgcag
    12301 gtggtttgct ggtaatatca tacacgatac ggttaacgtg tgcgacttca tttacgatac
    12361 ggacactgat tttttgcaag acttcccaag ggatacgggc aaagtcagcg gtcatgccgt
    12421 caatagaagt gacagcacgg atacctacag tgtagtcata cgtacggcca tctcccataa
    12481 ccccaacaga gcgaatgcct ggtaggacgg tgaagtattg ccagatgtcg cgatctaaac
    12541 cggcattggc gatttcttcg cgcaagatag cgtctgattc acggacgatt tctaattttt
    12601 cttctgtcaa ttcaccaagg acacgaatac ctaagcctgg tccagggaat ggttggcgcc
    12661 aaacgatgct gtcaggcatg cctaattggg tacctaattc acgtacttcg tctttgaaca
    12721 atgtgttcaa tggctcgatc agcttgaatt gcatgtcttc aggtaatcca cctacattgt
    12781 gatgtgattt gatggtttgg gcagtttcag ttcctgattc gatcacatcg gtataaaggg
    12841 ttccttgtgc aaggaaagaa acgccttctt caccggcaag tttggttgct tcatcatcga
    12901 agacatatac aaattcattt ccaatgattt tacgtttttc ttctggatca gacacgccag
    12961 caagttttga taagaaacgt tctttggcat cgacttttat aatgttcaag ccaaattttc
    13021 cgccaagact ttccataact tgttctgctt cacctttacg caacaatacg tgatcaacga
    13081 agatacatgt taattgatcg ccgatcgctt tttgtaaaag aacaccaaca acagaggaat
    13141 ctactccgcc tgaaaggcct aataaaactt ttttgtcacc gacttgttca cgaatttttg
    13201 cgatctccat gtcgatgaag ttatccattg tccagtcacc agtacattgg cagacatcta
    13261 gtgtaaaatg gcgcaacaag tcatttccat attcggaatg gcgaacttct gcatggaatt
    13321 ggattccgta cattttgcgt tctgcatttt ggatcgatgc gatggggcaa tctttgctgg
    13381 tagcaacgac atcgaaatca gtcggtgctt gggtaactag gtcaccatga ctcatccaaa
    13441 cggtttgttt ttcaggagtg ttttggaaaa gggccgcttc tgcagaagtg atttccaatt
    13501 ctgcttttcc gtattcacgg tttttggctg gtttaacttt tccgcctaat ttataagtaa
    13561 tcaactgcat accgtaacag attcctaaaa ctgggatccc caaatcaaaa atcttttcat
    13621 caataccaaa ggccttctca tcataaacac tgtttggtcc gccagaaagg atgattcctt
    13681 tagggttcat tgcctttact tcttctgcgg taatgcggtg gctcatcaac tctgagaaaa
    13741 caccgaactc acgaatacgg cgagtgatca gttggttata ctgactaccg taatcaagta
    13801 cgataatttt
//
LOCUS       DAZKNV010000064        13601 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000064 DAZKNV010000000
VERSION     DAZKNV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.065"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(116..1222)
                     /locus_tag="ACG8M1_002246"
     CDS             complement(116..1222)
                     /locus_tag="ACG8M1_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0422918.1"
                     /translation="MIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLSWSVIFLAR
                     SVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQFQPSELANL
                     FLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIAWVIFWAAA
                     VPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDSFIDSHGAG
                     YQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIGALCVLFLL
                     FSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGVPLPFVSYG
                     GTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     regulatory      complement(1396..1562)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(1787..1993)
                     /locus_tag="ACG8M1_002247"
     CDS             complement(1787..1993)
                     /locus_tag="ACG8M1_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422919.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2009..2623)
                     /locus_tag="ACG8M1_002248"
     CDS             complement(2009..2623)
                     /locus_tag="ACG8M1_002248"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFQ0422920.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2770..3453)
                     /locus_tag="ACG8M1_002249"
     CDS             complement(2770..3453)
                     /locus_tag="ACG8M1_002249"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFQ0422921.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3562..4020)
                     /locus_tag="ACG8M1_002250"
     CDS             complement(3562..4020)
                     /locus_tag="ACG8M1_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFQ0422922.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4104..5867)
                     /locus_tag="ACG8M1_002251"
     CDS             complement(4104..5867)
                     /locus_tag="ACG8M1_002251"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFQ0422923.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6088..7548)
                     /locus_tag="ACG8M1_002252"
     CDS             complement(6088..7548)
                     /locus_tag="ACG8M1_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422924.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7756..8682)
                     /gene="glsA"
                     /locus_tag="ACG8M1_002253"
     CDS             complement(7756..8682)
                     /gene="glsA"
                     /locus_tag="ACG8M1_002253"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFQ0422925.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8705..10132)
                     /locus_tag="ACG8M1_002254"
     CDS             complement(8705..10132)
                     /locus_tag="ACG8M1_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0422926.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10163..11377)
                     /locus_tag="ACG8M1_002255"
     CDS             complement(10163..11377)
                     /locus_tag="ACG8M1_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFQ0422927.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11463..11690)
                     /locus_tag="ACG8M1_002256"
     CDS             complement(11463..11690)
                     /locus_tag="ACG8M1_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422928.1"
                     /translation="MKNKFENRSDTRCGSFLYILYEVFFIPYEKISLKIKKDENKRFS
                     IKRRPFIFCLYLCEKRKRAQHIKLLLIVCLL"
     gene            complement(11718..11960)
                     /locus_tag="ACG8M1_002257"
     CDS             complement(11718..11960)
                     /locus_tag="ACG8M1_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0422929.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(11992..12549)
                     /locus_tag="ACG8M1_002258"
     CDS             complement(11992..12549)
                     /locus_tag="ACG8M1_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0422930.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12562..12750)
                     /locus_tag="ACG8M1_002259"
     CDS             complement(12562..12750)
                     /locus_tag="ACG8M1_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFQ0422931.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(12763..13329)
                     /gene="amaP"
                     /locus_tag="ACG8M1_002260"
     CDS             complement(12763..13329)
                     /gene="amaP"
                     /locus_tag="ACG8M1_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFQ0422932.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4066 a         2810 c         2220 g         4505 t
ORIGIN      
        1 tatgattttt tgagatactt tcattgcgaa ttcctctttc taaaagaacc tctcgcttga
       61 aaaataaaag attgtacttt atgataattc aaactgagag tttctcagtt tctctttatt
      121 gtttttcagg tcgatagagc gccaactctt cggcctgtat ctttgaagaa atattcaacg
      181 tgattccgat tcctaaagaa aggatcagat aacttgttcc tccgtagcta acaaatggca
      241 atggcacacc agtcattggc atcagccccg cgatacttcc cacgttcatt atcgtctgaa
      301 cgaatagcaa agttccgaat cctaaaagaa acaatccagc ttgctgattt ttacagcgac
      361 tgcttaaaca aaagattctc atgcataatg agaacaataa gaaaagcaca cacaatgcac
      421 cgattagccc aagctcttct gtaataatcg aaaaaataaa atctgtttct gtctctggaa
      481 gatacccttt ttttgtgata ctatttccta atccccgccc aaatatgcca ccattatata
      541 gtgcataaaa cgaatgggtc atttgatagc ccgcaccatg actatcgata aaagaatctc
      601 ttaaagtcgc gatcctttca taagcatgat taaacatctg tggaagccaa cctttatttc
      661 ctaaatataa taccccgcct gctgctccaa tcagcaatgc agaaaaagta acgattagat
      721 agatcccttt tttaaatgga accgccgctg cccaaaatat gacccacgca atcgaaagga
      781 tcatcaatgc tccagcaatc tttggctgaa ataaaatcag aaaagttata cctactgtaa
      841 tcaggaatgg tttttttaga tcttttgggc tactatttcc gtcacgaaaa aaccagctta
      901 aataaaaaat caaaaaaaga tttgccagtt cagaaggctg gaattgaatg ccaaacagag
      961 agatccaacg ttgtgcgccg ttgacagtga caccgaatat ccctattctt actaatacta
     1021 aaaagaaaat cgataaggct aaaccgtatc ctgctatttt agggtgaagt aaatagtgta
     1081 gtttgactga acgagctaag aagatcacgc tccaactcaa aaatatgaaa attagttgac
     1141 gcaataatag actttttgta ttttcatcgg cttgcaataa acgataagaa ctggcactgt
     1201 atacttctaa aagaccgatc atggacaaag tcaaataagg acccaaaatc caccaatcga
     1261 tcttttttca ccgcatctcc tcctcacaca gcaatccact tgtcaggtga ggagcgagtt
     1321 tgtctcatca aataagtcag tcacaaaaat ataaagaaaa ggtcagaaac cttttcgaac
     1381 aagaattctg acctagcatc atctcatcgt ccgagtttta gcactataca acgtaaagaa
     1441 aacattctta gctattggaa aaagccttaa tccaacagtt tctgttttac ccattggcga
     1501 ctttcgacgt ttctgggcaa cagcctatgt ttgtatagga gcctcaccta acaaggttat
     1561 tactatattc tatttacgag ttcatgatag acttttccta atgattaggc aatggaattt
     1621 gaaatgaaat agtgaaattt aacaatcttt aatatttttt agaaaaaaat aacaaataag
     1681 ttgaaagaat cccgttgcaa attctttcag ttgcaccagg attctttgat aattttttag
     1741 ttttatgtgt ttttttatat gttttttcac ttttcggaat aaatatttat ttgttaaagt
     1801 aattaaacaa tccgctaatc gtttgatctg gcatttctat ttccttacca tctaaagtaa
     1861 cagtagtaac gacaaaatgg tcttgcaatg gcggaacttc taagtactgc ccttgcagaa
     1921 aatcattcac tgtttcatat tcttttttca tttcttttga atctgtcgat ggtttatagc
     1981 ttatttttaa cataactagt gctccttttt attcgggacg tgcaatcgtg aaaatttctc
     2041 ctattgctgc ataatcattt cctgccaaac ggcttacagc attcaatttt cttggatcga
     2101 tccttcctgt cttatcatca tagactgttt catttaaatg atatttctgt acttctagca
     2161 aaaataaatc agctgttact ttatttttat tccgtatctc gacatgttca tataaggatg
     2221 tttcaaaacg aacttttgct tctgtcaatg ctggtactga aatgattact gaatcagtta
     2281 aagtcaagtc agtcaggtac agttcgcttt cctcattagg cagattggct gctgttttat
     2341 ttacttcttc tacgttgtcc tcatcaagga tatggataac agcttctctt gtctcaagaa
     2401 tattctttgc tgtgtctttt actgcatctt gttttctctg gatcgccaag gataagatgg
     2461 gtcgattcga actgacgata ttgaagtaac tgaagggtgc gatattcact atatcttttg
     2521 ctgatttagt cgttactact gctactggtc tagggatgac tgaaccaatc agcaacttgt
     2581 aattttcacg ttctgtcaat tctgaaggac tccgttcaaa catggtttcg ccttctttct
     2641 ataaaattcg ttaaaaagca gatcttgaag acaaaatgaa aagtaatgct tttttcatct
     2701 tcttagaatc tgctttaaac tatctatcaa tttttctttt ttgtcaagaa tctgtgccgt
     2761 gcgtgttttt tagttatttg ctttacttgc ggcttcgaca tatcttttag tgatcaattg
     2821 cggacgggtg ataatagatc caactacgac tgaaaaagca cctaattcat atgctttctc
     2881 tacttgttca ggagagtcag tatgtccttc cataattact gggatatcga cttgttctat
     2941 gatttgattc aataaatcaa aatcaggtgt ctgcgtcttt cgtgaatatt ctgtatagcc
     3001 tgctaaagtc gtagacaaaa gatcaaaacc atcttcttgc gcttgaagcg cttcctcaaa
     3061 agtcgaaata tctgccatag ctaaccgacc gtgttcgtga atcatttgga caagttcagc
     3121 agttgttttt tctgtcggac gtttacgaga agttgcatcc agtgcaatga tttctgcttg
     3181 cgtctccaaa agttcttcca cttctttttc tgtcgcagta ataaacactt ctgacccatc
     3241 gtaatctctt ttgataatcc ctattaccgg taaatcaacg attcgcttga tttcattgat
     3301 atcttctgtc gtatttgctc gaataccaac tgctccgcct tcttttgcag ccaaagccat
     3361 tctccccata ataaaagaac tgtgtagcgg ctcgttttcc aaagcttgac aagaaacgac
     3421 gactccgcct ttgatttgtt ccagtgtatc cacaatatct cctccagtaa tgttatataa
     3481 aaatacagct tcatataaaa atgtaaccct tttctattca ggagacaata atgagctatt
     3541 tctttcagca gacctttctt actaaaagaa aattacttca aattcttcgt atacgaccag
     3601 cttctcttct gtaaattcta tgttcaacgc ttctttataa gcatgtttaa aaaactcagc
     3661 atggactttc cgccaataag ctaatgtccg atccccttct ccttctttcc aagcatgctc
     3721 tttcgtgact tcactaaaag gcaagatggt cacatttata tttttgatga tacaaactgg
     3781 ttcatttttt ccattcagga ccacgtctaa ttgaccaact tttggtaaag gctcattctc
     3841 ttgtttatac agatcgtaac cacttgatgt accagtcttt atctttttta caactagttc
     3901 gctcaactcg tctgccattt tttctgtatc cccaaatgaa aagaaaccta atttttctga
     3961 ttgataacta ggatattttt cttggaactt tttgacatat tcttctactt gctgatacat
     4021 aacatccacc cctttgcttt ttataatgaa aaaaccatcc agatactagt ataaacaatt
     4081 atctggatgg tgagcataat gaattattga atattcaaga cacgcagact atcttcaacg
     4141 atttgttttg gtgttaaatg ataacgttca taaagctgcc ctacaggaac gctatccgtg
     4201 aattctttct ctgcaccaaa atttaatacg ttcattgaag aatcaccata ataacgactg
     4261 atattttcgc caaatcctcc tgacaaacta ccatcttcta atgtgatgac taattcgtgt
     4321 gtttctttta atttatctaa tgtttctacg tcattttctg tgatcgttcc tggattgatc
     4381 aacgttgctt cgattccttt ttttctaaaa gcttttactg tttcttttcc taattcaaga
     4441 aaaccgccta aagctaaaat tgctactttt cctccattat ttactgtttg ataggctgga
     4501 atactataat catttgcgat agctgtacca tgttctacac catgtgtagg aattcggatt
     4561 gctacaggct gcgctgtttg ttcgaacgcc caatctagca tagagatcat atcctctttt
     4621 gttgctggag caagatattt gatgttcggg atacttgata agtaaggaat gtcaaatgtt
     4681 ccttggtgtg ttcggtcact agctgagatc gttccgccac cgactaaaat aatcactgga
     4741 ttctcgttga tcgctaaatc atgtgataat tgatcatatg cccgttgcaa gaaagtactt
     4801 gattggaaga cgactggacg tactccctga gaagccaaag cagaagcgaa agtgatagag
     4861 tgctgttcag cgatccccac gtcaaaataa tgatctggat gtttttcttg gaatgttttc
     4921 agtccaaagg cgcctggtat cgctgcattg actgcggcaa taggagctgt acttgtttgc
     4981 attttcttat ccaaataatc catgatgatc atattaaatg tttctccaga agttacttgc
     5041 tttgcctccc cggtggacag atcaaatggt acatgccaat gatatttcat tttattatcg
     5101 attgccggct gataaccgcg acctttttcc gtatggacgt gaagtacaat cggatgatca
     5161 atatctttta cttcttcaaa taaacggatc accgtttcca gatcgtttcc attatccacg
     5221 taacgataat caaatcccat tgctttaaat aggttattgc tgcttttacc gttggtttga
     5281 cgaagctcag ctaagttttt atataaactg ccatgattct catcaataga catctcatta
     5341 tcgtttacta atacgattag attggattgt aaaacaccac cattgttcaa tccttcaaaa
     5401 gctaagccac cacttaggga gccgtcaccg ataaatgcta ccacatttcc tgattctttc
     5461 ttcagatctc tcgctttagc taaacctgtt gctaagctga tagatgtaga tgtgtgcccc
     5521 actgtaaaat agtcatgttt actttcatgt tggttggaat atccgctcac ttcacggtaa
     5581 tgtccttttt caaaaccatt ttttcgacca gttaaaagct tatgaccata agactgatgg
     5641 gaaacatccc aaacgatttt atcctttggt gaatcaaata cataatgaaa cgcaatcgtt
     5701 aattctacta cacctagatt cggaccaacg tgcccaccta catcgctgtc cttttgcaag
     5761 attttttggc gcatctcttc tgccaactgt ttcatttcct caacagataa ttttttgaca
     5821 tctgcggggc tattgattgc atccaataca tgtaatactg tactcataat acattctctc
     5881 ctccgtacta tcttctttta atgaaaatag atttgttaca ctttatctat tctactactt
     5941 agagttgact ctaagtcaat agcattttaa aaaaatttca gagaaagctt gttatataag
     6001 tagatcttcg cacgaatcag gactcaaata aaaaccttct acagacaatt aaaaagcttt
     6061 gtagaaggtc tcctaattaa ggtctcatca agaaatatgt ttttttaata ggtgaagttc
     6121 ctgagcaata tgatacaaat ggatgtttgc accttttaat gagattggat agatctttgt
     6181 cttttcagtt tctaatccat tttgatagct agcagcatcg cacaaaacca ctcttttttt
     6241 cgcacataga cattcatcag gcaattcttc taatgaacga aataaaatag gatttatttc
     6301 agcgatgcct tcttccgcat acaaatgaaa ttgggttcga taaaaaaatt gtttgactga
     6361 actttctgaa acaacaaaaa tttctatttc ctgtctcccc gcttgttcac tgttgatcaa
     6421 agaaagactt ttgacgaatt ttcgaatgaa attttcattc catcttagtt ggatttgatt
     6481 tttctttttc cactcttcca atatttctac aatttttccg tacagaagtt gttctttttc
     6541 tgatagaaga tagatccttt ccggtaaaaa tacttgtcca tctgcccaca acgtacggac
     6601 aaattgtaaa aaggattgct tgaaaataaa attttctgca tcgtcgattt cagcgatact
     6661 aataatctgt aaaatcaatt cattcagtga taggtcattg agaacaaaat ttttataaac
     6721 aacttcgaaa tcttttctta acagctccat gttctcattg gtataatttc tactgttgaa
     6781 caaagaaaaa atataataga catcttcttc ttgtaagtct agaattcctt tttgctcttc
     6841 caatccttga cagactaatt gaaataacgg cttcgtttct gcgcttttct tatcttcttc
     6901 tttcagtcca aggggaaatg cctttcttcc gattgcgatc tctattcctc gtatgataaa
     6961 ggacttttca tcttccgaat atcttctttt aaaaaaatga gtctctacat aatcaatcaa
     7021 ctcgttacaa gcttcttcta catacggatt tttattttca tagccttccc aattgacata
     7081 acgtactaaa gctagcaaga tgttccgcga gtcaaattct gggataatga tttctttatt
     7141 tttcaaataa tcattttctt taaaaaaatc caatacgatt tttttgattg tatatacttt
     7201 gctcaaagaa ataaattcaa gatcagccag ttctgtactc gtgaatatac cattaaaata
     7261 ataacttaaa aactttaaaa aataagattg accgtacaga aactgtgtga gctcagaaag
     7321 agcaatacca tgtttgaata cgagtttata cttatgcttc tctcttactt gttcttttat
     7381 acaatattct agacactcgg ctagactttc tagatcgtga aggatcgttg gtgtagtcac
     7441 ccttagagaa atagctgttt gttcgatgtc tatttcttgg aattcaaata attgttcaca
     7501 cagatacact tttctaaata tatttcgctc gatgtaattt tccagcattc ctgatacacg
     7561 cctccagttt ttcttatgat tttatttaat catatctgta aatcgtattt ttgtttcctt
     7621 tttatttaga aaagcccttt caaaaaccaa taaaaaaaga aactgggaca aaagtcaaac
     7681 aagctcacaa tttcagcctc attgtaggta gctttgagcc gtttggactt ttaccccagc
     7741 ctctttcaag aatggttatt caaagatgtc agcgtctagt tctttgacta catctttcaa
     7801 caattggata ccagctgcgc tgttaccaaa tggatctagt gccgggctga agacacctat
     7861 gccgtaacga tttggcacag ctgccatcaa cccgccgcct acaccgcttt ttgcaggtac
     7921 accaacatgg acggaaaact ctcctgattc atcatacaaa ccagcagttg tcataattga
     7981 tttgacgatt gtagcacttt cttcagtaat gatttgtttg ccattccaag gagcaattcc
     8041 tttatttgcc agcacagcag ctaattttgc tatgcctgta gcggtgacat tgagggagca
     8101 ttgtctgaaa taagcatcga gtatctccgg tacgtctcct tcgatcattt gattaccttt
     8161 catatagtaa gcaagagagc gattgatatc acctgttctt gattcagaat gatagatttc
     8221 ttcattcaat gtgatattag gatcatcaca gatctctttc ataaatgaca agattcgctc
     8281 aaatttttca tctgcatctt taccggcaat caacgaggtt gttgcaatcg ctcctgcatt
     8341 aacaaaagga ttcattggat gtttgcgatg attgatttcc atattcatga tagaattgaa
     8401 ggcaaaaccg gttggttccg tgttgattgt ttgaaagact ttttctattc cgttgtcttt
     8461 gattgctaat aacaatacgg gaacttttga catgctttcg atggcaaagc gcacatcggc
     8521 gtctcctccc tcaatcagtt gttttgtatc caaatcataa atcgccatac ctaattgttt
     8581 gggatccact tcagctaatg ctggaatgta atccgccact tgtcctgttt gataatagtg
     8641 gaaatttttt ccaatcaatt gttctaattc ttttacttcc atttgaataa ccagctttca
     8701 ttttttattt ttctgcatgc tggaatttat gacggcatgc gtagatcgta aatggaataa
     8761 ctaagacgat aagataagaa acaatcagaa tcgtttcata aatcccatgc tgtccagctg
     8821 cgatactagc aggtggaaca aatgagatac aaaaagcaaa aagtgaagtc aaaagaccta
     8881 aacaagcaac gattactttt acaacttttc cgcctggaac ctgataggct ctttcaagac
     8941 tgtcatcttt aaaaaccagc ttcaaatagc ccgcgaaaaa cataaagtac aacatcaggt
     9001 agattacaac agtcaatgac atcgctgcaa gaaatgaaag attattcccc ccgccgctta
     9061 atgtaaagac ggctgcccag attgttgcaa cgatcccatt tgcgatcatc aaatgagcag
     9121 gaacaccgtg tgtgttttct tttgcaaaat attcaggaag taatccttct tctgctgcta
     9181 cgtgaagtgc ttttgaagga gaggttaccc aagaagcaat ttctccgatg acacctaaac
     9241 aaacaagaat cgcaagaatt ttcgcaatcc atgcaagatt tggatcaatg tgtcttaata
     9301 ggaattctaa cgattgaatc acccctgtat taagagacaa accatgttga ggtactgtag
     9361 tagcgacggt caatccgcca aaagtatcta aaatgattgc cagaataacc aatacaaaca
     9421 ttgctaatgg ataatccttt ttagggtttt ccatttcatt tgcatgactg gcagatgttt
     9481 ctacgcccat atatgctaaa ataaaggaaa caaaaacaac cagcgtaggc aatttcgaaa
     9541 aatcaggaat caatgttttc atagacagta tcgtttgtag tggagcgcct gaagcgacat
     9601 aatggatccc taagccaaac aagactaatg ctggcaacaa gataccagct acaaaaccga
     9661 tccgagcaat caatgaagtg tatttggttc cttttaactg tgagagtaaa atagcccaga
     9721 aaataatcaa taggattgcc aatttcagat atttattgtt ttgtatagca ccaatacccg
     9781 ttgcatagga taatgcacca gttaagaaat acagcatggt caagtagcca actgttatct
     9841 caaaccattg gaaaaagatt gcggcaaaac cgaatcgttt tcccaatgtg cgactgaccc
     9901 aagtatagac accgcctttt tcccatcctt tcaccgttgc catctctgct gcgcacaatg
     9961 ccacagggat aaaccatagc aaaccgccta ataacaagaa aaatactaag ctgaagcctg
    10021 aggtcgcgaa tgtgggatat tcatataatg aaacgaccat tgagatggtc atagccaaaa
    10081 agccaaagaa cgttaatttt tttgcaggaa ttttcgtttt gctttgttgc atgaatcttc
    10141 ctcttttcta ttttaatttg tttcaattga gtttgttgcc aaagaagaaa aagtccaatc
    10201 cttcttcttg ttcttctttt gtagtagtga tcgttgtaaa gtgcatcgcc gattttaaaa
    10261 tcactgttgt cagcacatag gcatacacgg cagtaatgat gacaccaatc acttgaatcc
    10321 ctaagaagta ccagctgctt ggattcgtta gtaaatggct gttagatgca aagatcccta
    10381 tcagaatcgt acctgtgaat ccgcccatgc catgaacacc ccacacatca agtgcatcat
    10441 cccattgttt ctttttacga aaatcaacag cagcatgaca gacgataccc gcaatgatcc
    10501 caatcagcat ggcacttttt gcttctacat aaccggcaca aggcgtaatg gctgccaatc
    10561 cagcaacgga tcctgttagt acgtcgacaa aatcaaagcc atttcctttt acttttgcaa
    10621 tgatcagcca agtaatcatc gcaaatgcaa gagcgatgaa tgttgaacca aatgcattga
    10681 ctgcttgttc atctgctcga agtgcaccac cggaattaaa accgaaccag ccaaaccaaa
    10741 gcagtcctgt accgatagca gctgccataa gactgctatg ctgacttctt tctcctaaag
    10801 gaatctttct ttgaccaagt gtgaggatac atgctaaaga gccgaatcca gctgtcgtgt
    10861 ggatgactgc tccaccagcg aaatctctaa atcccatctg atccaaaaat ccgccacccc
    10921 atatccagtg gcaaacaggg aaataaatca gcagattcca aaaaataaca agtataatat
    10981 agccttttaa attcaatctc cctgcaaaag ctcctgtcat caaaggaacg gtaatcacga
    11041 taaacatcag ttggtaaaga aagaacatta aaaatggaat cgttgcacca tgaaacatgt
    11101 tggggaagct tgtaacatgt ctcatcaaaa agaaatctgc cgggtttcca ataacaccgc
    11161 cgatatcccg tccaaaggcc aatccgaatc caccaaatac ccacataatc gttgttatcc
    11221 caacggagag aaaagattga gacatgatcg ttagtatatt attcttccgt gctaatccgc
    11281 cgtaaaaaaa agctagacca ggagtcatca ggcaaaccat tgctgtacat aaaatcatga
    11341 atgctgtatc tcctgtattg ataggtaatg tattcatttt tttcgcctcc tttctacgat
    11401 tacgagtata aaagaaggtg tagttgtttt tttcttctgt ttttttgaat taatacttgc
    11461 atttataaaa gacagacaat taataaaagc ttgatgtgtt gtgctctttt tcgtttttca
    11521 cacaaataaa gacaaaaaat aaacggtctt ctttttatag aaaaccgttt attttcgtct
    11581 ttttttattt ttaaagatat tttttcataa ggaataaaga atacttcata taaaatatat
    11641 aaaaaagaac cgcagcgagt gtcgctacgg ttctcaaatt tgttcttcat ttcaacataa
    11701 gtttttcttc aatttgctta taatttacgt gcaaagaatg aaacgactaa tactaaaatg
    11761 attgcaccga tcaatgatgg aatgatagcc attcctgcaa ttgttggtcc ccaagttcct
    11821 agtaaagctt gtccaattgc tgaacctact aaaccagcaa tgatgtttgc gatgatcccc
    11881 attgatgatc ctttattcgt gattgctcct gcaattgctc caatgatacc gccgacgatt
    11941 aatgcccaaa taaatcccat tttaaattcc tcctaactga cttcttactt cttattgtac
    12001 acgtggttcg ttattttctt tgactttttg tgcacctttg cctacagcag attttgcttt
    12061 atctgtttgg cgtgaagcaa attgtcctgt ggattttgct gcttctgtta ctttgtcttg
    12121 tactgtttct tgatcttttt ggtattcttc ttgtgttttg atgtctgcaa cattcacatt
    12181 cacttcgata acatctaaat gtgtcatatt gtttacttca gtactgatca attctttgat
    12241 ttggttgtaa atatcttcga tgtctttacc gtattctacg atcacatcta gatccacagc
    12301 tacttgtttc ttacctactt ctgtattgat acctgctgtt acgttatctg tgttgactaa
    12361 tttttcagcc atatttgaga aaaatccgcc atctaatgtc aatagaccat ctacatcttt
    12421 caatgcataa ccgatgattt tttggatgac tttgtcttca taagtcaatt caccattcat
    12481 catgcggttt tctccttttt catttgccaa aactgatcca tttgttgtat tcatgttttt
    12541 gttttccatc tttgtttcct cctatgattt aaaaaattga tcaactattc ctgactgttt
    12601 caaataaaaa ccgattcctg cgccaattgc tgtcatgatt atgatcaaca atgtcttgaa
    12661 aaatccaatc gttaaccata aaacagctag cagtagtcca agacccccaa agataatagg
    12721 gagcttgtat gctgaaaata gttctttcat tatttggccc tcctattcca ctcgagagtg
    12781 cttgtagtct cttgtatctt cttgttcttc ataaccgctg tatgtgactg ccactttgac
    12841 cgtttctttt gttccgagta ctttagttac ttcttcttcg atatcttgca tcaatacacc
    12901 tgttttccct actaatgaag aagttcgttt caagtctccg ttgacatgga tatggattcg
    12961 atttttcgtt gaacgtatcc gtactttagg tgaatgaatg aactcttctt cgtgtaaatg
    13021 ggaacgtacc aacccttcga tcgctttttt gtcgattgtt agtttgccat cttcccgttt
    13081 cataacgaaa gttcctcttg actttggata gaaaagaacg actagcaaga tgataatagc
    13141 aagaacggca aatactacag ctgcccagaa aatatattgt tgcatgtagt aattcgttaa
    13201 agtaaagaag cgaaatcgtt ccaattgttc aggcataata tacggcgcat tgatcaacgc
    13261 aatcgctaga aatactgaaa gtagcagtaa actcatgata acaccgatta tttttaaccc
    13321 cttattcatt ttccacctcc tataaactta tttttaccct gtaaataact ctaccgacaa
    13381 tcacagtata gatagcgaac agttagcata gcatcagtaa ataaagcgct accaaacatt
    13441 gctggatcat aacggcgttt tattgccagt ctgatactga aataacaatt gcttacttat
    13501 tctctattta cttttgattg ctggctatac ttaaaggata ttattcaaga ttaaaaattg
    13561 caaagattat gctcagttat tattacaaga ttctatttat t
//
LOCUS       DAZKNV010000065        13429 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000065 DAZKNV010000000
VERSION     DAZKNV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.066"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..914)
                     /locus_tag="ACG8M1_002261"
     CDS             complement(<1..914)
                     /locus_tag="ACG8M1_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFQ0422933.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="ACG8M1_002262"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="ACG8M1_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFQ0422934.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="ACG8M1_002263"
     CDS             2006..2176
                     /locus_tag="ACG8M1_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422935.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="ACG8M1_002264"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="ACG8M1_002264"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFQ0422936.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="ACG8M1_002265"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="ACG8M1_002265"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFQ0422937.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /gene="dapA"
                     /locus_tag="ACG8M1_002266"
     CDS             4440..5321
                     /gene="dapA"
                     /locus_tag="ACG8M1_002266"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFQ0422938.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /gene="dapB"
                     /locus_tag="ACG8M1_002267"
     CDS             5318..6034
                     /gene="dapB"
                     /locus_tag="ACG8M1_002267"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFQ0422939.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="ACG8M1_002268"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="ACG8M1_002268"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFQ0422940.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="ACG8M1_002269"
     CDS             6751..7752
                     /locus_tag="ACG8M1_002269"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFQ0422941.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="ACG8M1_002270"
     CDS             7749..9110
                     /locus_tag="ACG8M1_002270"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFQ0422942.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="ACG8M1_002271"
     CDS             9070..10221
                     /locus_tag="ACG8M1_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0422943.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="ACG8M1_002272"
     CDS             10196..11365
                     /locus_tag="ACG8M1_002272"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0422944.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11540..12919
                     /locus_tag="ACG8M1_002273"
     CDS             11540..12919
                     /locus_tag="ACG8M1_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0422945.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13200..13429
                     /locus_tag="ACG8M1_002274"
                     /pseudo
     CDS             13200..13429
                     /locus_tag="ACG8M1_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4484 a         2339 c         2924 g         3682 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgaggaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    11461 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    11521 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    11581 agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    11641 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    11701 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    11761 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    11821 ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    11881 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    11941 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    12001 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    12061 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    12121 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    12181 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    12241 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    12301 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    12361 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    12421 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    12481 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    12541 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    12601 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    12661 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    12721 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    12781 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    12841 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    12901 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    12961 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    13021 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    13081 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    13141 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    13201 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    13261 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    13321 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    13381 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DAZKNV010000066        13407 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000066 DAZKNV010000000
VERSION     DAZKNV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.067"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            137..310
                     /locus_tag="ACG8M1_002275"
     CDS             137..310
                     /locus_tag="ACG8M1_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422946.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="ACG8M1_002276"
     CDS             950..1423
                     /locus_tag="ACG8M1_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFQ0422947.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="ACG8M1_002277"
     CDS             1432..1659
                     /locus_tag="ACG8M1_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0422948.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="ACG8M1_002278"
     CDS             2295..2666
                     /locus_tag="ACG8M1_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422949.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="ACG8M1_002279"
     CDS             complement(2922..3164)
                     /locus_tag="ACG8M1_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0422950.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="ACG8M1_002280"
     CDS             complement(3196..4098)
                     /locus_tag="ACG8M1_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0422951.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4111..4299)
                     /locus_tag="ACG8M1_002281"
     CDS             complement(4111..4299)
                     /locus_tag="ACG8M1_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFQ0422952.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACG8M1_002282"
     CDS             complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACG8M1_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFQ0422953.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4914..5807)
                     /locus_tag="ACG8M1_002283"
     CDS             complement(4914..5807)
                     /locus_tag="ACG8M1_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0422954.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5885..6808)
                     /locus_tag="ACG8M1_002284"
     CDS             complement(5885..6808)
                     /locus_tag="ACG8M1_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0422955.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6857..7207)
                     /locus_tag="ACG8M1_002285"
     CDS             complement(6857..7207)
                     /locus_tag="ACG8M1_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0422956.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7240..8142)
                     /locus_tag="ACG8M1_002286"
     CDS             complement(7240..8142)
                     /locus_tag="ACG8M1_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFQ0422957.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8135..8992)
                     /locus_tag="ACG8M1_002287"
     CDS             complement(8135..8992)
                     /locus_tag="ACG8M1_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFQ0422958.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9326..10135
                     /locus_tag="ACG8M1_002288"
     CDS             9326..10135
                     /locus_tag="ACG8M1_002288"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0422959.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10175..10672
                     /locus_tag="ACG8M1_002289"
     CDS             10175..10672
                     /locus_tag="ACG8M1_002289"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFQ0422960.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11057..11130)
                     /locus_tag="ACG8M1_002290"
     tRNA            complement(11057..11130)
                     /locus_tag="ACG8M1_002290"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11094..11096),aa:Ile,seq:cat)
     gene            11317..11640
                     /locus_tag="ACG8M1_002291"
     CDS             11317..11640
                     /locus_tag="ACG8M1_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422961.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11804..12058
                     /locus_tag="ACG8M1_002292"
     CDS             11804..12058
                     /locus_tag="ACG8M1_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422962.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12128..12373
                     /locus_tag="ACG8M1_002293"
     CDS             12128..12373
                     /locus_tag="ACG8M1_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0422963.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12449..12814
                     /locus_tag="ACG8M1_002294"
     CDS             12449..12814
                     /locus_tag="ACG8M1_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFQ0422964.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12875..>13407)
                     /locus_tag="ACG8M1_002295"
     CDS             complement(12875..>13407)
                     /locus_tag="ACG8M1_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422965.1"
                     /translation="SFFKEYLEIINFRLKTKKESVIILVYFQGGNLMIKKLFLLSILT
                     LAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGILGRSNCKHRCSN
                     RRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREVGDEPKLEYAFS
                     FAREDEDNPKTYDILA"
BASE COUNT         3907 a         2476 c         2244 g         4780 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
     4141 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
     4201 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
     4261 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
     4321 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
     4381 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
     4441 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
     4501 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
     4561 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
     4621 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
     4681 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
     4741 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
     4801 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
     4861 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
     4921 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
     4981 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
     5041 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
     5101 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
     5161 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
     5221 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
     5281 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
     5341 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
     5401 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
     5461 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc aactttcacg
     5521 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
     5581 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
     5641 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
     5701 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
     5761 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
     5821 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
     5881 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
     5941 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
     6001 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
     6061 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
     6121 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
     6181 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
     6241 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
     6301 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
     6361 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
     6421 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
     6481 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
     6541 caaaagatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
     6601 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
     6661 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
     6721 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
     6781 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
     6841 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
     6901 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
     6961 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcga
     7021 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
     7081 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
     7141 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
     7201 tttccattcc tactccccct cttcagttgt tgtcttctat tatttaacaa ctacatctgt
     7261 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
     7321 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
     7381 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
     7441 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
     7501 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
     7561 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
     7621 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
     7681 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
     7741 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
     7801 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
     7861 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
     7921 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
     7981 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
     8041 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
     8101 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
     8161 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
     8221 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
     8281 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
     8341 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
     8401 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
     8461 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
     8521 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
     8581 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
     8641 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
     8701 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
     8761 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
     8821 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
     8881 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
     8941 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
     9001 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
     9061 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
     9121 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaaaggtat tgaccaaaaa
     9181 ctactatata tagccacctt tttcttaaga atgttttttg aaaaaattca taatgacaaa
     9241 gcaagttagt ttcatttttt taaattctca tttaatctta aggtaacagg aaaatagata
     9301 tgtaaaaaga aagtaggaag ataaaatgaa actagcagcg attgatttag acggtacctt
     9361 gcttgatcga aatggaaaga taccagaaga aaatatccaa gcacttcgga aatttgatga
     9421 aaatggcgga atcgtaaccg tcgctaccgg aaggaacagc atttctgcta aagatatttt
     9481 ttccgaatta ggaatcggtg gctatttgat ttcttccaat ggttcactga ttgctgaaat
     9541 gaaggatgga aaaatggcga aagttctcag acgttcaaaa atagatagcg atacactgag
     9601 aaaagccttc ttctatgctc aagaagcgaa aatatccatc attgctagcc gagaaaccca
     9661 agatgatcag ctgacattcg atgaatcaaa tctagtcaaa gatgaccctt attatgaaca
     9721 tttcaattta cagaaccatt cttttgatca aattttaaat atgttggaag atccttctct
     9781 tagctatctt aaattagcat taacagataa gagtgaagaa aaactacaga agctacaaag
     9841 agatctgcaa gcagatggta tccaatcagt attctctgat ccgcatttct tagaaatcac
     9901 gcctacaggt atcactaaag ctcattcact tgtttttctg gcggattacc ttggaatcga
     9961 atcgagtgac atcatggctt ttggcgatca agaaaacgac attgctatgt tgaattacag
    10021 cgggttgagt attgcgatgg ggaatgcaca gcgacaagta aaagaaattg caaaccaagt
    10081 aacactgacg aatgaagaag ctggtgttgc ttatatttta aaaaacttct attaaaaaga
    10141 ataaaatgac gatatgaatg taggaggaaa gaaaatgtta gttattattg atatgcaaaa
    10201 tcatattctt gatccaaaca gcgaatttta tattccagag tcagatcaat tggcagaacg
    10261 tattgctcaa agattagcta aagcacgcca aaataatgaa tatattctct tcacacggga
    10321 tataccagtt gaactgaagg acaaagaaga agaacgagaa gatttgcaat tgatccctct
    10381 tctttctcca caagaaaatg aacgagtgat taaaaagtat tactttacga ttccacctga
    10441 aactttagct gaaatccagg aaactttatt tgaaagcaaa gaagaacaaa aagagatcga
    10501 agtagtcggg attgaaacaa acttgtgtgt actctctaat ctgataggcc tgcagagtgc
    10561 ttttcctgaa gcagactttt ttgttgatcc aatgttagtc tccagtagaa aacacggaga
    10621 atccgcttta gagctgttga aagatttcaa cgtctctatc gtcgaatcat aaaaatatct
    10681 atcttcattt acgatattta acacacaata aaaaaagcac gcagaactgt tttagtccta
    10741 cgtgcttttt ctatcaaagt agattggctt ttttatgaca cagagtgaaa cggcaggctc
    10801 acgacctctt tcttaaatgg tgttcaatca gctgaccctc ggtattagct taacaaacgg
    10861 caaaatatga ggaactattt ttccgtttgt taagctaata ctcaggtcaa aacgctgatt
    10921 tcacaacctc ttccttaaac ggtattcaaa agcttgcatc tgcagtaata agaacagcca
    10981 agtaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct
    11041 ttttcacaac ctcttatgta ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
    11101 gtctgctcta accaactgag ctaaaggtac atcataaata aaatttattt ttgttacttt
    11161 tcaactatag cacgaatgac aaactctcac aagtttcaaa atataagtaa aataatattg
    11221 ttattcttat ttcttttact tgtgtcataa ctattttgtt actttaattt ttatttgctt
    11281 attttagaaa aaatgttatt cttttattta ttctcaatgt taggagtgat tattttgcca
    11341 tttattgcga ttttattcga tttagttgcg gcagcagctt attttctcca attaaattat
    11401 caaacctcag gaattctgtt tattggaatg atttttcaag gtgtgattac ccttttgctt
    11461 cttgtcatga tgctcagcta taaaggaaaa agatatgccc gtattcaaac aaaagtattt
    11521 gttaaatatg tttccattcg ctatgggatc atcattcttt cctttttagt gaatgcgatc
    11581 gtcctctttt tatatgtatt gaattactta gatatcaatc cattgatttt ttctcgatag
    11641 ataagacaca ttcagcggaa cagttcctgc ttatcagcag aaaactgttc tgctttttca
    11701 tttttcattg atctattctt cttttatttt cctagcattt catttgtgat gtatgcaata
    11761 acatgttatc ttttattata tgaatcgttg aggagtccgt tacatgatta cgttggtgag
    11821 agttttgttt tgggtgcctg cggtcgcact ggtcgcaagt attgtttatc ttatgaattg
    11881 gaacaaagaa cggttttatt tagctatttt gactcttccg gctatctact ttatgtggaa
    11941 agtttttaat tacaactact ttgaacccga tagtgttttt atagaagaat tatcaggact
    12001 ggttttgtct ttattgatcg tcattcttta tttgatacgt ttaaataaaa aacattgagt
    12061 actattgatt gcatgtgtag ctttctatag tcattataac tattctacta taatgaaagg
    12121 tgattaaatg agtatcgaag aagctatttt actggatact ttacgttgtc gtctgaattt
    12181 cttaagaact ggccgatctt tatctcaagt agctgtttct agcgcgttaa gtattccttt
    12241 attcaaatat cgtaagtacg aagaaggaga agaaattcca agcatcattg aattaatcta
    12301 tatcgctgac ttttacgata tttccgttga ttacctaatt ggtcgctcag aaacagcaag
    12361 caaactgaag tgattttttc cagccttggt gctggttttt tcatttaacg tctaaggtta
    12421 acaatctata tataaaggag acatttctat gcgattatgg catgaaaaat tgatttcaaa
    12481 gcttcctcgt caacagcttt taggacaaca tcgggaatgc tgtgcattaa gaggaaatgg
    12541 ctggggaaag aaacatgcta ctgtggatta tgtttttcac tattctcctt atagattatt
    12601 ccaatatcat cagcttgtca tggatgaaat ggaaaaacgt ggttacagcc cagcaccaga
    12661 gtggaaaaat cctatgtatc gtggcaaatc atgcgaagca ttttttgatt tacctactgt
    12721 agagcgcaac gtgccgattt atccggaaca cgatgaagtt tatctagcag aatgtttagc
    12781 aaatttggag caaaaaggaa tttatcttac ctaatataac tagaaaagcc ttctatctcc
    12841 tcttacttca ttaaaaagct ttaaccatct tagatcaagc taaaatgtcg taagttttag
    12901 ggttatcttc atcctcacgt gcaaaactaa aagcgtactc tagttttggt tcatcgccaa
    12961 cttccctaga cataaatgaa catctcctga cgtggtttaa aagtaccgca tcttcgacgt
    13021 ctgtatacga tgcacagcac agattgcttc ttttgatctt tcttttgatt tttctgttgc
    13081 ttcttctaca ccttcttcga ttactacatc gatgcttaca attgcttctg cctaatattc
    13141 ccatgcatcg tcgatttaag cctctgtagt cactgtgatc gtttccacat tttaactcct
    13201 ctgtcgtggc ttcagttgat tttgtgatca gttcagttgc taagccagag tcagaacaac
    13261 ctgccattgc tagcgttaat attgatagta aaaatagttt ttttatcata aggttccccc
    13321 cctgaaaata gactaaaata ataacgcttt ctttttttgt tttcagacga aaattaataa
    13381 tttctaaata ttctttaaaa aagctta
//
LOCUS       DAZKNV010000067        12156 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000067 DAZKNV010000000
VERSION     DAZKNV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.068"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..730
                     /locus_tag="ACG8M1_002296"
     CDS             <1..730
                     /locus_tag="ACG8M1_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0422966.1"
                     /translation="SILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNV
                     ALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSY
                     GGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINK
                     GEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLL
                     GSIQTNLPESVLLDCGMDFLKDIC"
     gene            788..2827
                     /locus_tag="ACG8M1_002297"
     CDS             788..2827
                     /locus_tag="ACG8M1_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFQ0422967.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLLAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2936..4087)
                     /locus_tag="ACG8M1_002298"
     CDS             complement(2936..4087)
                     /locus_tag="ACG8M1_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFQ0422968.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4241..4771)
                     /locus_tag="ACG8M1_002299"
     CDS             complement(4241..4771)
                     /locus_tag="ACG8M1_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFQ0422969.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4870..5220)
                     /locus_tag="ACG8M1_002300"
     CDS             complement(4870..5220)
                     /locus_tag="ACG8M1_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFQ0422970.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5377..6906)
                     /gene="ahpF"
                     /locus_tag="ACG8M1_002301"
     CDS             complement(5377..6906)
                     /gene="ahpF"
                     /locus_tag="ACG8M1_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFQ0422971.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6916..7479)
                     /gene="ahpC"
                     /locus_tag="ACG8M1_002302"
     CDS             complement(6916..7479)
                     /gene="ahpC"
                     /locus_tag="ACG8M1_002302"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFQ0422972.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7623..8285)
                     /locus_tag="ACG8M1_002303"
     CDS             complement(7623..8285)
                     /locus_tag="ACG8M1_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0422973.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8469..10115
                     /locus_tag="ACG8M1_002304"
     CDS             8469..10115
                     /locus_tag="ACG8M1_002304"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFQ0422974.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10106..11188
                     /gene="uxuA"
                     /locus_tag="ACG8M1_002305"
     CDS             10106..11188
                     /gene="uxuA"
                     /locus_tag="ACG8M1_002305"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0422975.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11296..>12156)
                     /locus_tag="ACG8M1_002306"
     CDS             complement(11296..>12156)
                     /locus_tag="ACG8M1_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFQ0422976.1"
                     /translation="TSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNIL
                     ARLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLA
                     FARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVIL
                     EKENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQN
                     DFMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMD
                     QSKKENQVTS"
BASE COUNT         4058 a         2257 c         2276 g         3565 t
ORIGIN      
        1 atctattttg ttactgctta cattagtagt tggctatttt tcgattgagt ttatccatgg
       61 attttcgtct gcaaaacaga gttcaactgt gaaaaaggta gagccgaaaa gtatccctac
      121 cacactaaat gtggctttga ttggttcaga tgctcgttcg aaagacgaaa acggtcgctc
      181 ggattcactt ctggttgcac aatacaacca gaaaacacaa caagcaaaac tgatctctat
      241 catgagagat tcatatgtcg atattccagg ttacggaatg aataagataa atgcagctta
      301 ctcttatggg ggagttgatt tattaaatca aacattaaag gaaaatttca aatttgaagc
      361 tccctattat gcaagtatca catttcaaga ttttatcgat tgcgttaatg aactgtttcc
      421 tggtggagtc aagatcgatg cagaaaaatc tctagattta gatggcgtat atataaacaa
      481 aggagagcaa gtgatggatg gtaatacttt actccagtat gctcgatttc gggaagacaa
      541 agaaggagac ttcgggagga tcagaaggca gcagcaagtg atcaaagcta tctctcagca
      601 gctgaaagac gtaacttcaa tattcaagct acccaaagcg gttgggaaat tacttggtag
      661 tatccaaacg aaccttccag aaagtgtgct tctggattgt ggtatggatt tcctcaaaga
      721 catatgttag aataaacagg tataaatagt gaaataaagg aatgacaagc aagagaagga
      781 ggaaaaaatg aaaagaagtg acaagcacgg caaaaatcga acaggcgctt atattgccgg
      841 cgcagtgatc ttaatagcag ctgcgggtgg cggttatttt tactaccagc actatcaaga
      901 aacccaagca gtagaagctg gagaaaagac agttgagcaa tttgtccaag ctttgaacaa
      961 gggagattat aacaaagctg cagaaatgac atcaaaaaag gcggcaaata aaagtgcatt
     1021 atctgaaaaa gagatcttag ataaatacca gaatatatac ggtgctgctg atgtcaaagg
     1081 acttcagata tcgaatctaa aagtagataa aaaagacgat tctacttaca gtttttcata
     1141 taaagcaaag atgaatacct cattaggtga attgaaagat ctttcttata aaggaacatt
     1201 agacagaaat gatggtcaaa ccacgatcaa ctggcaaccc aacttggttt ttccagaaat
     1261 ggaaggaaat gacaaagtaa gcctgaccac acaagaagca gcaagaggga atattataga
     1321 tcgaaatggt gaaccattag caacaacagg caaactaaaa caattaggag tcgttccaag
     1381 taaacttgga gatggaggcg aaaaaacagc caatatcaaa gcgattgctt cctccttcga
     1441 cttaacagaa gatgctatca atcaggcgat ttcacaaagc tgggtacaac ccgattactt
     1501 tgtcccattg aaaatcattg atggagcaac gccagaactt ccagctggag ctaccattca
     1561 agaagtagac ggcagatatt atcctttggg tgaagcagct gctcagctga ttggttacgt
     1621 gggagatatc acagcagaag atattgataa gaatccagaa ttaagcagta atggaaaaat
     1681 cggtcgctca ggtttggaga tggcttttga taaggatctt cgtgggacaa caggtgggaa
     1741 attaagcatt acagatgcag acggtgtaga gaaaaaagtt ctgatcgaac atgaagttca
     1801 aaatggcaaa gatatcaaat tgacaatcga tgcgaaggca caaaaaacag cttttgacag
     1861 tctaggagga aaagctggat caactgttgc gacaacgcca aaaaccggtg atcttcttgc
     1921 gcttgctagc tctccaagct atgatccaaa caaaatgaca aacgggatct cacaagaaga
     1981 ttacaaagct tatgaagaaa atcctgaaca tccattcatc agccgatttg cgacaggtta
     2041 tgctcctgga tctacgttta aaataattac agcagcaatc ggtctcgaca acggcactat
     2101 cgatccaaat gaagtgttga cgatcaacgg gcttaaatgg caaaaagaca gttcttgggg
     2161 atcttttcaa acaacgcgtg tcagtagtga tgtatcacaa gtagacttaa aaactgcttt
     2221 gatctattcc gataatatat atgcggcaca agaaacgttg aaaatgggtg agaaaaaatt
     2281 tcgtacaggc ttagataaat tcatttttgg tgaagacctt gatttgccaa ttagtatgaa
     2341 tccagcacaa atttctaatg aagatagctt taactcagat atcttgctag ctgatactgg
     2401 atatggacag ggcgaacttc taattaatcc tatccagcaa gcagcaatgt attctgtttt
     2461 taccaacaat ggcacacttg tctatcctaa attgattgca gataaagaga caaaagataa
     2521 gaagaatgtc atcagcgaaa cagcagtaca aacgatcgtg ccagatctga gagaagttgt
     2581 gcaagatgta aatggtacag cacattctct ttctgcttta gggattccgt tggcagcgaa
     2641 aactggtaca gcggaaatca aagaaaaaca ggatgtaaag gggcaagaga acagtttctt
     2701 gcttgctttc aatcttgata accaaggtta tatgatggtc agcatgttgg aaaataaaga
     2761 agatgatgat tcagcaacca aacgagcatc ggaactattg caatacctca accaaaatta
     2821 tcaataaaaa attgcttttt aagtacagta aaaggactgt ggcgttatcg tcacagtcct
     2881 tttttcaaat aaacggtttt cacgatgtct ctttcacaac ttctttttga tttactcaca
     2941 cttcataaac tttttttgta aaatatttga gaacaagtgg agaaataagt gtacttaata
     3001 aaatcacgat aactaaaggt gaatagtact gtggttcgat caattgactt tgctgtccaa
     3061 tttgtaaaat gatcaaagcc atttctccac gcgaaatcat accagcaccg accatcaatg
     3121 aactatgttg agaaaaaccg gcaatctgag caccaaaata acctccaagc aatttggtca
     3181 aaatcgctac aagcgtcaat atagaaataa agagtagttg ttcactaaag tcagaaaaat
     3241 caacttctaa tcctacactg acaaaaaata ctggtataaa tactgcatat cctaaagcct
     3301 ctacattgtg gtatacttct tctttaacct ttgtctgact gacagctatc ccagcaaaaa
     3361 aagcaccaat gacagagcta agcccaacaa gatccgctac gtaagacatt cctaaacaaa
     3421 taactagcga tacgatgata atagaagaat ttgcgtacac tttttctgca aatgaaagta
     3481 ggaaaggcgc aatccatttg actaataaga aaataaaaac aaaataaatt agctgttcaa
     3541 tcaaaacaag cggtaaagaa gcattgctag aagcttcccc cgttagaaaa gataggctga
     3601 aacttagaac taaaacgact aaaatgtcat ctaccacaga agcacccaaa attgttgatc
     3661 cttcttttgt attcactacg tttagttctt ttaatacttc tactgaaata ctgacagaag
     3721 ttgccgcaag aataatccca aagaaaatcg cttcatttcc cgaaacttgg aatgctttgc
     3781 ctgtcaacca gccaaaaaca accgggaaga tgatcccaag caaagcaacg aacataccag
     3841 gtcggaaata ttttttcaaa agagataaat cactttccag accagctaaa aacattaata
     3901 agatcacacc aatctccgaa aagtcatgga ctagaatatc aggtttgacc caattcaatc
     3961 cagcttggcc tagcaaaaca ccaacaagta attgtccaat cactgctggg atacctaatc
     4021 tccgcgagat atgtgagcca atcgttgttg aaatcaatat caggcataaa ataccaataa
     4081 attccattct catcattcct ttgtataaaa tatagcccga acttagcata acatacatta
     4141 ttgaaaaaat aggaaaatat actcacaaaa aaaccaacaa tccaaaagat ttttttggat
     4201 tgttggtttt tatacggtct attttaataa ctaaaaatga ttaacgtata gtcatttttc
     4261 ttattctgat gaaattgata atctcctgga tgcccatgaa aatcaaaata aagccgaata
     4321 tttggaatag aagcatcaaa cttttgaatg gattgaacaa taagacgaat ccgccaatca
     4381 acaacagaat actactataa acactccaac ttttagcttt tgtattcatg ctgaagaaca
     4441 actggaacaa gctgttgatg ataacagcta atccaagaag aatcggcagg atagaaacga
     4501 ttgcaggtgc aaaagcatag acgatcagag ctaagatcag gaaaaaaaga ccactgaaca
     4561 gaccgatact ccaagaacct gttttccttt taaaacggta agcctcaaaa agattcaaca
     4621 acccaagcaa aacaagatag gcggtgatca gataaccgat aaaatgaaaa acagcagaag
     4681 ggtttagcac aatcgcaatc ccagaaataa tataaacagc agctcttaat aaggcgtatt
     4741 tttgaatatt ttgtttaatc gtctcaaaca tataagaaaa cctcctttga cttattttaa
     4801 cgtgaactag tcattttacc aaattaaatg ttacaaaatg agcgaaggag aagaatatct
     4861 ctggaaaaat caacttctga ggatcttttc catttttttg ccttttgcta gctcatcgat
     4921 cattttatct aaataacgaa tttctttcat caagttatcc tcgatgtctt ctactcgtac
     4981 accacaaaca acacctgtaa tcaaggaacg tgaaggattg gggacagggg cttccgcaaa
     5041 aaattgttcg aaagtcactt gtttttgtag ttgatattct agttctgttt gggaataacc
     5101 cgtcagccaa caaatgattt catctacttc ctcttttata cgatcttttc tctccgcttt
     5161 tgctacatac ataggataaa cgcttgcaaa acttgtcgta aaaatacgat tttgcgccat
     5221 aatcagtcac ctttcttttt ttcaaattat ttactactta tagtatataa gaaaaagaga
     5281 agaaaaagcg attattcaaa aaaacaaaaa ggattgtgac aaaattcttg tcaccatcct
     5341 tttttccgct ctctgacttt ttacaatctt catagctcaa gtgcgcatca gataatcgaa
     5401 tgctcctaaa gctgcagtag ctcctgaacc cattgaaaca atgatttgtt tgtatggact
     5461 atctgtacaa tcaccagctg cgaaaacgcc ggggatattc gttgcgccat ttttctcggt
     5521 cactatttca tttcttggat tcatttcgat cgttccatct agccaatccg tattagggag
     5581 taagccgact agaatgaata ctcctgaaac agctagtgta tgcatctcca tcgtacggcg
     5641 atcgatatag gagagagatt ctacctgatt cgtaccgctg atttctttcg tcgctgcatg
     5701 tttgataaca gtgacattcg caagagagac tagtttatcc tgtaagattt gatctgcttt
     5761 taattctggt aagaattcta gaacatatac atgttttgct aacccagcca aatcgattgc
     5821 tgcttcaaca ccagaattac caccaccgat aacagcaatc tcttttcctt taaataaagg
     5881 gccgtcacag tgtgggcaat aagcaattcc tttattttta aactcttttt cgcctggtac
     5941 attgatagaa cgccagtgcg cacctgtcgc gatgatggcg gtttttgctt taagtgatat
     6001 accgttagct aagccaatat taataaaatg ttgctcttta tttaaggaaa cggcctgttg
     6061 attcatcata atgtcgatag ggtaactacg cacatgactt tctacttgct gcatcaattt
     6121 tggaccttct gtgtaagagg taccaatcat attttcaatc cctagtgttt caacgacttg
     6181 tccgccgaaa gaatcagcga caagtcctgt acggattcct ttacgtgctg catagatagc
     6241 tgcactacta gctgctggtc caccgccaat tactaataca tcataaggtt ctttttcaaa
     6301 caactcttct tcaatcaaag ggccagtgat tttttcaaca atttgttcga tcgtcatgcg
     6361 tccgctacta aattcttctc catttaaaaa cacagttggc actgccatga tttttttatc
     6421 atcgatttct ttttggaaca tcccaccttc aatcatcgta tgagtaatat ttggatttaa
     6481 tacagctaat atattcaatg cctgtacaac gtcggggcaa ttatgacaag tcaagctaac
     6541 ataactgtca aaatgcaatg tttgtgttat ttttttgatt ttaagactca aagattcact
     6601 gattttcggt gcccgtccac taatttgtaa catagccagt aaaaaagagg aaaattcatg
     6661 accgaggggg ataccagcaa aaacgattcc actttctttg ccaactggat tgatagaaaa
     6721 actaggtgtg cgcatcgaat ctcttttttc ccaagagatt ttaggagaca tttctgctat
     6781 ttccttcgta aattcagcta gtttttgact attttcacta ttatccaaac taacagaaaa
     6841 aacaatagga gattcaatca gtgctaaata ttgttcgaga ttttgtttag tttctttgtc
     6901 taacatatcc accacctaaa tctttccaac aagatcaaaa cttggtttca atgtttcgcc
     6961 actttctttc cattttgccg gacaaacttc acctgggtgg gtacgtacat attgagcagc
     7021 gcgaatctta tcaatcagtg cactagcgtc acgaccgatt ccatctgcat tgatttccat
     7081 agcttgaacg attccgtctg gatcaataat aaatgttcct cgctgagcta atccttgctc
     7141 ttcatccaaa acatcaaaaa tacgagaaat ctgatgagac ggatcaccga tcatcacgta
     7201 ttcgatttta ccgatagcat ctgatgtatc atgccatgct ttgtgagtaa agtgggtatc
     7261 ggtagagcaa gaaaagactt caacacctaa agatttcaat gtactgtatt gttcttgtaa
     7321 gtcttctaat tcagtaggac aaacaaaagt aaaatcagct ggatagaagc aaagaatact
     7381 ccagttcccc ataagatctt tttcactgac ttctaaaaat tctccttgat gataagcatg
     7441 tgcattaaat tcttcgattt ttttcccaat caatgacata gtaaaacctc caataataat
     7501 tatttattta taattattgt aatttagttg gagttgcaaa gtcaatggat attttgttat
     7561 ttaataaaga ttactcaaaa acgaaggtta attataaaaa tagaagaggt cgcaagaaaa
     7621 tgctactgct ggaaatactc gggataacgt tgagtaacag tttcctgttc tttcagcatc
     7681 atgtgtaagt gcaatcccgt ttgaaatcga gcttcttctg gttttttatc aactaaagcc
     7741 ttgagtaaat cataatgttg ttccatgatc gtttcccatg gaagcccctg aatggtcact
     7801 cgtaaccagc ggaaacgttc taaatgggta ttatggtcat ctaaccagtt ccaaacttct
     7861 tttcttcctg caatttcgaa acaagcttca tgaaataaat tatctgcacg gaaaaaagcg
     7921 cgttcgtcat ttattttgac tgctttttct tgttcttcta aaatcgtttc tagcactatt
     7981 cgtgtttgtg tgtccaattt ggaacaacat tcaatcatga tttgctcttc caactgttct
     8041 cggacaaagc gagcattttc tgcagaaaca agattaattt tggaaacata cgtaccactt
     8101 tgaggtatcg tatacacgag ttcttgctga cgtagttgaa tcaatgcttc gcgaatggga
     8161 gtccggccga tagcaagatg ttcctccagt gccttttcag atattttcct tccaggttct
     8221 aagtcagcat agataatttg tttacgaatc gcttgataag cttgtgattg caagctgctt
     8281 ttcatcttta ttcctccaaa atcatttcta tgaacgtagt ataacagaag aggtctgaaa
     8341 aacaatctgg tatgtcacat taactagtaa atttgtataa atagtaaaat tttggttgac
     8401 atagcgattt ttattgtata aaattcactt gaatacaaaa actaatatgt tagtttagga
     8461 ggggaaaaat gattgattta aacaactgga ggaactttat ccctgaatta tctcaaaaag
     8521 aagtagaaat acctcatttt gaccgtgcat cattaagaga aaatggacaa aaaaatcctg
     8581 tctggatcca tttcggtggc ggaaatcttt atcgaggatt tcatgcagaa atcgctcaac
     8641 gtttagcgga tctaggcgaa ttgtccactg gtgtcattgt ttgtgaaaca ttcgatgaag
     8701 aaataattga aagggcttac caagattttg atgatttgat tcttgaagtg gtcatgccaa
     8761 gcagtggaga gttcgtcaaa cgtatattag ctgcgacagc tgacagtctg tattgtcatc
     8821 cagattgttc tgaacacttt gataagatga ttcgacactt tgaaaatcct agtttacaat
     8881 tagttacttt tgctattact gaaaaaggtt atcgattgaa agatacaaat aataaatata
     8941 taggaccgat tgcagtcgat ataaaaaatg gtccaaagaa gccatcacat acaatgagta
     9001 ttcttgctgc gctactttat aaacgttttt tatctggagc ttggccgatt gcacttgtct
     9061 ctacagataa tttttcacaa aacggtagtc aattacgtac ttctttgcta acgatcgcaa
     9121 aagaatggca aaaggaaggt tatgtacaaa atacatttat ccaatactta tcgaatgaag
     9181 aaattgttgc gtttccatgg acgatgattg atcgtatcac cccgaatcct tccttgtcag
     9241 ttagcaaaat gttggcaaaa gagggctttt caaatatgtc gattttccaa accgcaaaag
     9301 gaaataatat tgctccattt gtcaatacag aggacatcca ttatttaatc atggaagatc
     9361 attttcccaa tggacgtccg aaattcgaaa aagctggggt attcttgact gatcgtgcaa
     9421 cggtagataa agcagatacg atgaaggtga cgacttgcct taatcctttg catacgtctt
     9481 tagctattat gggttgttta ctggggtata ggagcatagc tgaggagatg aaagatccag
     9541 atttatcgct gctagtttct gaaatcgggt acaatgaagg cctcccagtt gtggagtctc
     9601 caggtatcat tgatccaaag atctttctgg aagaagtaat tactgtgcgc ttttctaatc
     9661 caaatattcc tgatatgcct cagcgaatcg ccacggatac ctctcaaaag gtggcgattc
     9721 gttatggtga gacgattaaa aaatatatgg aaatagaagt taaagacccg cagacacttg
     9781 tattcatacc attgactctc gctgcttggc ttcgatacct tattggcatt gatgatcaag
     9841 gaaaaccatt catcccgagt ccagacccac tattgacaga ctttcagcat aagctttccg
     9901 atattcaact gggtacgcaa gatacatcac atattcatga gaaaatggct cctattttgt
     9961 caaataaaga aatttttggt gtagatcttt accaagcaga gcttggcaga aaaatagaag
    10021 aaatgttcat caagatggta gcaggaccga atgccgtacg aaaaacatta caggattact
    10081 tacaagaaca tggaggaaat ttatcatgga aatgactttt agatggtacg gatcacagga
    10141 agaaaagatt accttagatg aaatcagaca gattcctgcg gtcaaaggga ttgtaggcac
    10201 attgatggat ataccagtag gagaggtatg gcccagggag aggatcaaag aactaaaaga
    10261 agaaattgag tctcgtgggt taacactaaa agtaattgaa agcgtcaatg tgcatgatgc
    10321 cattaaaatt ggattacctt cccgtgagca gtatatcgaa aactataagc agacaatccg
    10381 aaacttggca gaatatggaa tagaagtcat ctgctataat tttatgcctg tatttgactg
    10441 ggtgaaatct gaccttgact accgcttaga agacggctca tccacgttag cttttatatc
    10501 tgatgatatt ccagatgatc caagagaaat cgtcgcgcgc atcgaacatt ccagcaatga
    10561 atttgaattg ccgggatggg aacctgagcg cttagctcat atcaaatcct tgcttgaagc
    10621 ctatgcatca gtagacgaag aaaaacttcg agaaaatttt gcctattttc tccaatcaat
    10681 catcccaaca tgtgaagagg taggggtcaa aatggctgta catccagatg atccgccata
    10741 ctcgattttt ggattacctc gaatcgtaaa gaatcgagaa gatttagatt ggttgtgccg
    10801 catagtagac agcccttata acggaatcac tctttgtaca gggagtattg cagaagatcc
    10861 agaaaatgat gtatatggga ttttagcaga attttgtcaa agagatcgaa tcccatttgc
    10921 acatgttcga aatattaaat ttttagctaa tcgagatttc tatgaggcac cgcataaatc
    10981 cgaatacggt tcattagaca tgtaccgcat actaaaaaca atgtatgaca acggatttaa
    11041 cgaatacatc cgtcctgatc atggaagaat gatctggaat gagacaggaa gaccaggata
    11101 cggcttatat gatcgagcat taggtgctgt ttatctaaat ggattatggg aagcaatcga
    11161 aaaaggaaac aaaagtaaag ataattagtg aaaaaaactg taattttatt atgtaaataa
    11221 gaaggatgtt caaattcttg atacataaat ccggaggttg ttaataagca ttcggattta
    11281 tgtatcttat ttggtctagg aagtaacttg attttctttt ttcgattgat ccatgagtgc
    11341 ttcttctttt aattcaaaga tatattctga gatcctcata atcacttttt tccagtcttc
    11401 tggtgtgatg attcctttta aaatatagat ttttttgata tgagaaggca attgtttcaa
    11461 agggcagtcg ctgataacga tgttgcagtt ctccataaaa tcattttgta ttttgatcga
    11521 ttcatttgaa aaaatttgtt ctatcttaac gatcagatct ttactgatat aaaaatcacg
    11581 cgtatagttc acaccaatca caattcgcgg ctgttttttg tagcgatcat acaaatgtac
    11641 taggtcttca accatccatt gcacattttc cttttctaaa ataactggta acaagtgttg
    11701 attttgttct ctgaaatcca tataaaattg ttcaatggcg gtttggactt ctttcaacac
    11761 gctatgttct tgataaagca tgaaagtagg aaggggcgta tttggttgat tgaagttaag
    11821 aaatccatta taaagtttat ttcgtgcgaa tgccaatgag taaagaatct tttctttttc
    11881 aggtataaac aaatcaaata cagtacaaaa ggactccacc atttctcttg aataaagaac
    11941 atgaggaacg tttgcttttt ttaaaagttt gtattgctcc aagcttgttt cttccgattc
    12001 gattttcgtg atagaaagtc gagctaaaat attcactaag atgcgttgtt cgcgacaaat
    12061 tggcagatta ggtcgcaaaa tatctacaga gggatcaata aaaaagtcaa tatattcata
    12121 ctctgtgaat tctttttgta cgtctttcac agaagt
//
LOCUS       DAZKNV010000068        12136 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000068 DAZKNV010000000
VERSION     DAZKNV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.069"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..610
                     /locus_tag="ACG8M1_002307"
     CDS             <1..610
                     /locus_tag="ACG8M1_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0422977.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="ACG8M1_002308"
     CDS             723..1001
                     /locus_tag="ACG8M1_002308"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0422978.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="ACG8M1_002309"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="ACG8M1_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFQ0422979.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="ACG8M1_002310"
     CDS             1458..2213
                     /locus_tag="ACG8M1_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0422980.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="ACG8M1_002311"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="ACG8M1_002311"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFQ0422981.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="ACG8M1_002312"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="ACG8M1_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFQ0422982.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="ACG8M1_002313"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="ACG8M1_002313"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFQ0422983.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="ACG8M1_002314"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="ACG8M1_002314"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFQ0422984.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="ACG8M1_002315"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="ACG8M1_002315"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFQ0422985.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="ACG8M1_002316"
     CDS             6950..7492
                     /locus_tag="ACG8M1_002316"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFQ0422986.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /gene="atpA"
                     /locus_tag="ACG8M1_002317"
     CDS             7515..9071
                     /gene="atpA"
                     /locus_tag="ACG8M1_002317"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFQ0422987.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="ACG8M1_002318"
     CDS             9085..9987
                     /locus_tag="ACG8M1_002318"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFQ0422988.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="ACG8M1_002319"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="ACG8M1_002319"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFQ0422989.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="ACG8M1_002320"
     CDS             11430..11852
                     /locus_tag="ACG8M1_002320"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFQ0422990.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4035 a         2155 c         2677 g         3269 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttattt
//
LOCUS       DAZKNV010000069        11463 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000069 DAZKNV010000000
VERSION     DAZKNV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.070"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(34..519)
                     /locus_tag="ACG8M1_002321"
     CDS             complement(34..519)
                     /locus_tag="ACG8M1_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HFQ0422991.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(521..1957)
                     /locus_tag="ACG8M1_002322"
     CDS             complement(521..1957)
                     /locus_tag="ACG8M1_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFQ0422992.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPH
                     YCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDIL
                     KSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGN
                     SIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLE
                     SGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQ
                     ALEKLDTEGEVDKKVEQIVSLINSIQED"
     gene            complement(1990..2841)
                     /locus_tag="ACG8M1_002323"
     CDS             complement(1990..2841)
                     /locus_tag="ACG8M1_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFQ0422993.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(2997..3242)
                     /locus_tag="ACG8M1_002324"
     CDS             complement(2997..3242)
                     /locus_tag="ACG8M1_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0422994.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            3347..4120
                     /locus_tag="ACG8M1_002325"
     CDS             3347..4120
                     /locus_tag="ACG8M1_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422995.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(4173..4487)
                     /locus_tag="ACG8M1_002326"
     CDS             complement(4173..4487)
                     /locus_tag="ACG8M1_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422996.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(6006..6224)
                     /locus_tag="ACG8M1_002327"
     CDS             complement(6006..6224)
                     /locus_tag="ACG8M1_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422997.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            complement(6239..8866)
                     /locus_tag="ACG8M1_002328"
     CDS             complement(6239..8866)
                     /locus_tag="ACG8M1_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFQ0422998.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            complement(8853..9071)
                     /locus_tag="ACG8M1_002329"
     CDS             complement(8853..9071)
                     /locus_tag="ACG8M1_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0422999.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            complement(9068..9943)
                     /locus_tag="ACG8M1_002330"
     CDS             complement(9068..9943)
                     /locus_tag="ACG8M1_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423000.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            complement(10208..10507)
                     /locus_tag="ACG8M1_002331"
     CDS             complement(10208..10507)
                     /locus_tag="ACG8M1_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423001.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            10709..>11463
                     /locus_tag="ACG8M1_002332"
     CDS             10709..>11463
                     /locus_tag="ACG8M1_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423002.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIA"
BASE COUNT         3559 a         2120 c         1443 g         4341 t
ORIGIN      
        1 acatgtcatt agatagtaga cagttccaac tctttattta ccttttttgt atgctgcact
       61 gtcaatccaa gttcctaaat tgttgtatcc atcatcactt atataatcat attggccatc
      121 aataatttcg tcaaaccaca aatattctcc atctggtttt tgcccaatta ttttaattac
      181 tgattgacta gtagttgtca tctggttaaa atcttttatt ttacctatat taacggccaa
      241 aatagcattt cctcgcttat aactctcctg gatttcatat ttaacatatt ctcgatcaag
      301 agtttcttta cctatcagca ccacagtcac tgatgttcca attaattgat tatctatcca
      361 gttttttata gcaatatctc cattacgttt aactttctca aattcagcct tatctacaaa
      421 accagcttcc tttgttcctc gcaaagtcca gctgtttcta actaccattg ctcttgttac
      481 atctgcataa tggaaactaa aaaaaaccct tctcaccata ttaatcctcc tgaatactat
      541 ttattaaact gacaatttgt tcaacttttt tatctacttc tccttcagta tctaattttt
      601 ctagcgcttg aaatttactt tttaaggaat catcaaaata atcactgaaa ttctcttgaa
      661 tcttatcaaa caaaacctta cttgcacctt tggtaaatcc aatcggaact actatatttt
      721 cattttgaac agataattca aattcttcaa tcattccatc tgctgtaact atttcacctg
      781 attcaagttt gtttccaaaa acaaaaatac taatcccaga ctctgcaata atgttttctc
      841 gatatcttct ccactcatga ggcatatcaa ggggaagtgg tcttaaagaa agtacgtctt
      901 gtatgttatt ttttcttaaa tttcttctct gctttagaac tcctgaaaca atactattac
      961 caattccaag tccgtaacct gatactattc tataaccgga ttcagaaagc ctatatgcta
     1021 atttctcgac aaattttaat cctttcgatt cagatgtaaa tggagtataa tcaacagcac
     1081 ttcccgaaat aaaaatagtt tttctcaaat acttttttct aatacttttc aaaatatcag
     1141 taatctcaga ataatcatct acttcaacaa cgtttatcga aaatctggac aaatcattga
     1201 tttgtagtct tctttttgtc agttcataat tatatctctc ttgatcaaaa aaatcctcag
     1261 aatcgacaaa attttccttt aatatttttc tcattataca ataatgaggt ctttggtttt
     1321 ctctcaaaac ccatcttata tctgataaaa ttctttctaa attagggtct gtaaaactaa
     1381 atcctaaaaa gagaaaagtt tttgttaaca aatctccttt taaagtttct ttaaataacg
     1441 cgtacgaatc atcatcatat ttttcataat catctcttgt tattactgtc gaactgacat
     1501 catctatatc accatgcatt ttataaacaa ttgtatccac atttggatta gttgttgcta
     1561 actgagtata atttttctta acctgagggt ttttataagc ttctcggatt gatttttcta
     1621 ttagatgatc ataattagtt gtccaataag tttcaatagg taaacttgct agtattcgat
     1681 gattttcaga tatttctaat tcttcaccaa aattatccat aagtatctga ttcaaaattc
     1741 ctcttgatcc accattttca tttttataat attgagccag agtaactaag tctgtttctt
     1801 ttttagaatc caacccgatt tctgttgcag gatcattaag tagttccggc caacttacat
     1861 atccttgtga catcgataat cctgcacctg caaatattgc tgcatttcct ttttcaatag
     1921 cttcagagaa cctctttatt aaaactttct tatccattct acccggttcc tttcgattca
     1981 gtaaattgat tagagattag tgaaaatggt gtttttatat aaaatatcta atgtattact
     2041 tcctttagtg cattccacag catctaaagc ccattttttc aaatcagctt ttcgtaaata
     2101 agttaattca cttaaattta aagaatattt tatttgcaga ttttcttgcg aagaatagtg
     2161 ctttataatg cttctaacat cctcggtgct catttgagga ttactttcca atcgtggatt
     2221 ctttttttcc actattgaag ctgtcgtcag ttcgctatat agccatggcg aatacgtaaa
     2281 tttctgttca ttagtgattt cattgctcaa actaattgaa ttaggtgtat taagaaaaaa
     2341 cagacattct gtactatcaa tcatattatt taaagctgta gaaagcatca tatgaacatg
     2401 actagttgtt acatttcttt tatcataatc atatgttttt gtttgttcct tatagcaata
     2461 tttttggtct atttttttta ataaatcaga actgtatccc caaaccgaag aatcaataaa
     2521 tgcagtaaga ccaaaatttt caaatagcca tgatgcaaaa cgtatagcta atttttcatc
     2581 agcatgagag tgagatataa aaatatctgc ttttatagtt ggaaaccaat ctttaataat
     2641 ttcgtctgca tctagaattt tgctgtcctt agaataataa tcaactaaat cattttcact
     2701 ttcaaataga ttttctattc tcttgttaat agatttttgg ttgtgatcta tttgatttac
     2761 tacatgtgta tatgattgcg agcttgagga gaatgcattt aagtcagcat ttgtaaaatc
     2821 caattcatat gccttataca aggatatccc tccattcttg tattttgatc cacaatttat
     2881 taggcaacat aacagtatac cctatcgtta catatcccat tcattattat accagtattt
     2941 cttcgtgaca cataagggtg taacataata atttcaaacg aaatgactac aagtagtcat
     3001 tgaagcaaat cttcataaga cacctgtaga atatctttga tggctttcaa ttgatccaac
     3061 ttaatgtgtt ggcggccacc ttcaatctta accaacgttt ccctagttat agcaatttta
     3121 cgaagctgta ggtctctaat cagctcggtt tgaccaattc ctttttctaa tcggactcgt
     3181 ctaatattgc taccgattac attttcttta tcaataattt tttcctcttt caagaatagc
     3241 acaccttttg gactaaaatt agtccttttt cttattaatc ttaaagattc ggtatgctac
     3301 aatgggacta gtattagtcc atattcaatt ttaaggagga atttttttga agaaatttgc
     3361 aatcattcta acttgcgctt tactcatcgg aactataagc gggtgtacca cttctgacac
     3421 aagttctaca agtacggaaa ctagtacaac aacctcagaa aagaattacc caatacattt
     3481 ttttccggtt ccagatggat ttgaagctta ttatcatgat aaaaaactag atgttccttt
     3541 atcagaaact gaatctactg aaaagatttt gccaattgaa attgaaagaa atcaagacga
     3601 tataaaacta aaagctgatc ttcccttact gaacagcaca caaattgata gacatgaaaa
     3661 tattaaagtt aatattgaaa aaggagcgtt agcacaactt tatactgaaa aagttgaaca
     3721 attttttgag gctggtgcca ataaagactt ttcaaaaata agcgattatt cggataactt
     3781 ttttaatgag acccaagatg aaatcacgaa ctcaactttt atggctgaag atatgtacaa
     3841 tatgaagttg aaaaaaataa agtcgtatga ttatccatta aatctaacat taaataaagg
     3901 gatactctct tttgtattag caggttacgt tgactatgaa tatacagcag attatttgga
     3961 gacgcccctt caacacgata ataacgatat taattttaga tttatctaca attcaaaaag
     4021 taaaacatgg ttagttgatc aattgagcac tataaatacg ggatttcatg aattacctaa
     4081 gcctgacaat gaaactgctt tggtcattaa aacattctaa aaaagaaacg ttgaaggaat
     4141 aattattctt tcaacgtttc ttttattgtt tttcagttta cggtcttacc tgagcgaata
     4201 atctgatttc taaatgattg gaaaacttct tgtggttgat aataatctgt atctatttca
     4261 aatgtttctg agaataattc attgaatttt tctactgaaa tgatgatttt accattctcc
     4321 tctcgactgt tttctattat ttctgcctct aattcaaata aatctagtga cgaactaaaa
     4381 tcataaatcc tgtcatattg aacaaaaaaa tcaagaaaaa gttgctcaaa ctcttcctta
     4441 tttatcacta gtgtttcaag cggaacaact ttattttcat cagccattct tccaatttcc
     4501 tcactttcat tttcaattgt ccattgttgc ggacgtatca gattttctct atcatttttc
     4561 agtgtataga tcacttgtaa tacacaacaa tgctttgtaa acttattttt ttagttagtc
     4621 gaatcttttt aaatgtgcgt ttcataccat gcgcttgata tattttctcc tattttttaa
     4681 atcgtttatc acaactttta tcgttttttc ttctgaaaaa aatcttgttt acatcgttac
     4741 atagtttcca aaaagataca ttactagtag aaacaacaag attaatttta cttcccactg
     4801 aaatgggaag tatattttaa atattttttc tccttcaact tacactataa agtatcttaa
     4861 tcacacgata tgctagccac taaattcatc atatttgatt ccttttttaa gataatgtag
     4921 catcttttta tccaataacg caattgtttt taaggataaa tttcttaaga tggtacattt
     4981 caaaatggca tttgacatat gaaacaaaaa agaaagaaaa gagcataagg gaaaactgat
     5041 agcaccttcc tacaggaagg tggctaagtt ggctgtgcca actggttttc tttcaaaatc
     5101 atttcataat ttttgatatc ataaaaaaat ccattttgga cctattttcg gtcataattt
     5161 agtacctact tttggtcata gtttcgtccg tagttttggt catagtgact aaggcttttc
     5221 tgttcacaaa attggtttaa atttgctttc tttaacactt catttatatc atagcaatta
     5281 taatgtttac acaacatcat tcctaatttt aacggttgtt cctctttata ttttttaagt
     5341 tctacatttt tttgcgttta attacttttc tcttttcttt atattccgct ccaactttct
     5401 ctttaatagt gataatagaa ttacatattt ttgttaaact tccttaaaaa aattggatct
     5461 cgattactca aatttgcttg caggcttttc taattgcttt gttttttctt cctaattatt
     5521 tgattttatt tccattttct tctagtgaaa atttattatt tttaataatc gtacgcgtag
     5581 aactgatttc attttttgta tctgtttgat tatctaacgt ttgaaattca aagttttgat
     5641 tggctttatc aatatctttt tatactactt tatttgcaag atatattttc ttgcttaatt
     5701 tggtcatagt ttcattcgtc acttcggtga tattttttta atttgcaaat aaaaagagtt
     5761 aaaccgatat acattaggtt caactctttt gcaggtttca tgggtgtact atcactttta
     5821 atctgataga tgtaaacctc tctttatctt tttgttactt caattttcaa caatagctcc
     5881 tttataggtt gtcaatattg ctctacgtat tctggctttt taacccatta tttctctaaa
     5941 gtggaagaga ataatcgctt aatccccact aattccttgt cgtaaattca tgtcaaatac
     6001 aatttttaaa agccatttaa ttcatggatt atctcttcac ttttttctag ataacaatat
     6061 ttcaagttgt tttttatctc atgtttcatc tttaattctt cttgaatcat cagttcaata
     6121 taattagtga ccgtgatttt ttcatttgtt gcgttcttta ctgattcaca taattcgtca
     6181 agttctaaga aatcatgcgt actaatcttt agaattaatt tcatgacaat tccccctttt
     6241 atttttttaa tagattatcg aaaagcggat taggatcatt aagtgtatct ctgaataact
     6301 cgttgtcttc ataggtaaat cttcgtcttg gttttgatcc cttatcattt tcacggattt
     6361 cactatcaat aatcactgtt tcatgatttg aatcaaattt tttcgctgac tttctgtctt
     6421 caacgatatt gattttttgt gttttttctt tcatttctcc actatctttt tgaacgttct
     6481 cccgaacatc tactgttttg aatccttgac tacttgtaga actttgtaca ttctctctta
     6541 catccattga tttaaaccct tgactacttg tagaattttg tacattctct cttacatcca
     6601 ttgatttaaa cccttgacta cttgtagaat tttgtacatt ttctcgaaca tcaattgtct
     6661 tagtaccttg accatttgaa gagctttgta aattctctct tacatcaaca ttccgtccga
     6721 catgaccatt caatgaacct tgaatatttt ctcggacatc tactgatcgg ccaccttgac
     6781 tacttgtaga attttgtaga ttttctttga ccaatttttc taatccggta tttgagtttt
     6841 tagcttcttg gattctttct ttggtcaacg cttctttttc gtccgtatta gctcctgtac
     6901 gcccttctac acgtttcctt aacatttcct cacgattcat tgcttcaggc gtgtatttag
     6961 cttcttgtcg cttctgatta attaattctt cagcagactt agcttgaccg tgcatagcat
     7021 ttttacgttc ttcaatatct tgttgaactt tttgctgaat tgcacttaca ggattattat
     7081 tcgattcagc attatttttc attgcttcac gcatacgttc agaactagac ataattctat
     7141 cggcattttc aaccttagca ccatcttttc tatccgaaag acgtgttggc atggaatcag
     7201 catattttcc agtttcatct tctttatttt tagctaacat aggtttgcta tttttattaa
     7261 tagcggacac tgtaccatca tctaaacctt ctttgaactt attcttggta tcattagcca
     7321 tatcacgcat actcttaaat ggttttattg ctctttcact agccattgta gctccatctg
     7381 aagctaaacc tgataatcca cgttcatggg catatcccaa agctcttcca gttttgccag
     7441 ctttttttga tagagtttcg ccgaaattct tttctggttt tcgatcttct ccttctccac
     7501 tgtctgatcc atttccattt ccgcttcctt tagcacgatt aaatccagtt gatccttttc
     7561 taaacagcat tgcgcccata ccaaaagcag aagcaagttg cccatagcct tctttgagtc
     7621 caatatcaac accaaagtat ctcatgactg ttccactgcc ttttatcagc acaaacacag
     7681 cacagatata agcaattgtt tttataaaaa tatttgtgga gataccttgt ccagcattta
     7741 aaaaattgat aaacatagca aacatagata gtccaaaccc ttgaaatcca actgttaagt
     7801 aacattgtaa aatatcggat aaaacaactt ttgaacgttg tcctgtttca atatctgtcg
     7861 caaaaacaag aacacctaac acacgtttaa atgcaagttc taatattgct gtaatgatca
     7921 caaacgcgct gaacacatag gcgattgcca acgctgtcaa cccaatcgaa atcccccaaa
     7981 gatttgcttg atatcgataa taacctgatt tcaagctatc agaaaatgtt gataagaagt
     8041 tatcagaaaa ctttgtggca acaaattcat tattagaatt ttcaactaat tcatagcgaa
     8101 gattatccgc agctggattt tctttttcca atttatcaat cactttatcc gtcaacactt
     8161 gtgttaaatc tgtctgttga aaattttttc gtgttaactt atttcgatcc tccgttttat
     8221 caatgcttga gtattgatct gttttattaa tatatgccag atctgttact ccttgtttta
     8281 tcaatgacca agcgactccg tcatctgaat ttgtaatcgt agtagcatca ttgtaaaata
     8341 ttttggcaaa ttgaataccg ctagaaatca ttgttggcat taaaagaatt aacgctacag
     8401 acatcactat attcattcca acagatctta aatctattgt tccttttcca gtaatcatct
     8461 tgtagccaac aaacatcaat gaaaggatca ttaatccaac gacaattgta tttatgactg
     8521 attgataaac attatttagc cctgtacttt caatgaaatt gaacaaatcc aacacatctg
     8581 gaatcatatt ttgaatcgaa tcagtcacag taaacatgcc ttttaccaca gcccatccaa
     8641 gccaaatccc gaactgacta aggaaatctc cattgtattt ttttaggtaa ggtctataaa
     8701 gagaattatt caaaaactct gtttgacttt ttgtgtcatc aaaccaattg aaaatgctag
     8761 cttcaacaat attacttgta aaaacaacgc taatcattaa aacaagtaca ctgagtgcta
     8821 accagtttat ttttctacta acgatttttt ctttaattgc tttcatagtt ttctccttca
     8881 gcccattttc ttaggctctc agagagctgc tgagccattt tttgattaat tatgatatga
     8941 gttacacaat tgtcattttc agctcttaaa tcgagaacta ctgtgttgaa gcagatactc
     9001 tcgattaatt cgagagtatc tgtattttga tcaagacacc acatttgatc tattaagcga
     9061 tttttaatca tgattcttct cctttcaacc aattatgcat agtaatttca ggtaactctt
     9121 tgatttcgaa agcttttttg aactgatcta taggctctac attttctaaa aattgacttt
     9181 tatatctttt ctgaagtcca ttcaaaaaat atgttacata atcgtataac ccttcttcag
     9241 tttttctttg aaaaaagcat gcttcatgtt gttttataat acactcagca ataagatact
     9301 gagtattttc agataaatat tcaatgattt ttctgatatc ttctgtatct acattagcgt
     9361 ttctcaaata gtgatacact tgaaataatt ttcgaccatc ttcgttattt gcgtcataaa
     9421 gaacactaat cttactgtaa atcctcttta tattaatatc ctcttcttcc ataacgagag
     9481 tagtctttga tatgttctgt gaagtagtct ttgtatacgt atatacaaat ttgtacatac
     9541 ctctaccttt ttttaaagag acatatctct ttttttcgat acccctctga cgaattttcg
     9601 gcatatactc ctttttttcg caatccaaag taggaaaagt aatttctatc aatttatgta
     9661 catttaaaac aatgtacata acatttgata atgtaactgc tcttttctca taataaatat
     9721 ttctaaaaac ccttttgata atcccctttt tctctaagta cacaattgca tcttttatag
     9781 ctcgttctga taatcctgtt tttttgctta attgcttata tgatttttgc aaaatatctt
     9841 caagaaactt tttttgataa ccaagtagct gaccatcatc gttaaaaatt tttttaggtc
     9901 tataccaata ggtaatttct gctaagataa ctattgcatt caaatagggc ttctcaacac
     9961 cttttttcgt tttttttctt aattgatcgt accatgtgtg tggattacat ttccgtcaaa
    10021 atttatttct ctaagtttgt caactacaac atttccagaa gaaaacacct tttcaccttc
    10081 ttttttgata taatagctat aaataaagtt ttctcagcac tttattattg agtgttcccc
    10141 cagtctgcaa acttttggga acactttttt tcttttttta aagcattttt ttataatttc
    10201 tacttcatca tcttccaata ttttcccctc ttttcattcg agcaaacata aactcattaa
    10261 ctgccttttt cgaataaaat tttcttgccc ctaattcaac tacgggcaat ccctcatttc
    10321 tcacagcatt ttttaaaaag ttttcactca catttaagta ttccgccatt tctttttgat
    10381 tgagatattc ccttgtcatc cccgcatttt cttgagcctt ttcaatagct tttgtagcaa
    10441 tttgataaaa ctgctttaga aacatttcct cctgttcttc tgaaatcatt aattttattg
    10501 cttccacaaa aacctctcct ttttaattaa ttattctata actcctctac ctttataagt
    10561 acaaataaat acaaattgcg taaaaaaatg tatttatttg tatttataag aataaagtat
    10621 catactccag ataaaaagta aatactttta aatactttta ttttataaat atgatatact
    10681 atctttaaaa ataaaaagga gaaaaaagat gaagccaaat ccttcagaag caggaaaacg
    10741 aatcaaacaa ttacgccttt catgtggttt tactatggaa gaacttggaa ggaaaataga
    10801 taattcacca cgtgcgacca tatccaactg ggaacgtggg accaatttac caaatccaca
    10861 aaagctgaaa ttattatcaa ctatcactaa ttcaacaatt gactggatta aatggggaac
    10921 tttagaagaa tatataactt cataccttat cgatataggg tatgagctat atattaagga
    10981 cttcccagaa atacctcaca aagtctttaa agacattcaa gaaagatata gtgatacgtt
    11041 ttcgctagat aaagactatg agttattgaa tcctataata aaaaatatat ttacaaaata
    11101 ttactcaaaa gattttgaaa tttatctaaa tgagatactt gctaataata tcaatcctct
    11161 gattgaagag tacgctaacc aaagacactc tatctctaaa gagctatttt tcaaaagagc
    11221 caacagtaaa cttcaagaca agataagaaa tggtgatttc aaatacggtg aaaaagaaag
    11281 aatgattgat tctttaaaac agctattaga cgaaatggac ttagcctata aagatatttc
    11341 aaagtattca tctgtcgagg atttctttta taaaattact aaaaaccaat ttgaaacaga
    11401 aaaatttatt tcagatctta gtaaaaaata caatttccca tatgagaaaa atagtataat
    11461 cgc
//
LOCUS       DAZKNV010000070        11445 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000070 DAZKNV010000000
VERSION     DAZKNV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.071"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            185..1183
                     /locus_tag="ACG8M1_002333"
     CDS             185..1183
                     /locus_tag="ACG8M1_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0423003.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="ACG8M1_002334"
     CDS             1295..1804
                     /locus_tag="ACG8M1_002334"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFQ0423004.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="ACG8M1_002335"
     CDS             complement(1834..2493)
                     /locus_tag="ACG8M1_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFQ0423005.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="ACG8M1_002336"
     CDS             complement(2495..3259)
                     /locus_tag="ACG8M1_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFQ0423006.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="ACG8M1_002337"
     CDS             complement(3267..3944)
                     /locus_tag="ACG8M1_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFQ0423007.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="ACG8M1_002338"
     CDS             complement(3981..5366)
                     /locus_tag="ACG8M1_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFQ0423008.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="ACG8M1_002339"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACG8M1_002339"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACG8M1_002340"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACG8M1_002340"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFQ0423009.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="ACG8M1_002341"
     CDS             6305..7162
                     /locus_tag="ACG8M1_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423010.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDGTEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="ACG8M1_002342"
     CDS             complement(7243..7578)
                     /locus_tag="ACG8M1_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423011.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="ACG8M1_002343"
     CDS             complement(7645..9015)
                     /locus_tag="ACG8M1_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0423012.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="ACG8M1_002344"
     CDS             complement(9093..9629)
                     /locus_tag="ACG8M1_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0423013.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="ACG8M1_002345"
     CDS             9938..11419
                     /locus_tag="ACG8M1_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423014.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3517 a         2300 c         1855 g         3773 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatggtactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttatt
//
LOCUS       DAZKNV010000071        11148 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000071 DAZKNV010000000
VERSION     DAZKNV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.072"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACG8M1_002346"
     CDS             6..305
                     /locus_tag="ACG8M1_002346"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0423015.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACG8M1_002347"
     CDS             378..1739
                     /locus_tag="ACG8M1_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFQ0423016.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACG8M1_002348"
     CDS             1761..2021
                     /locus_tag="ACG8M1_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423017.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACG8M1_002349"
     CDS             2035..2787
                     /locus_tag="ACG8M1_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFQ0423018.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACG8M1_002350"
     CDS             complement(2881..3486)
                     /locus_tag="ACG8M1_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0423019.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACG8M1_002351"
     CDS             complement(3542..4516)
                     /locus_tag="ACG8M1_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFQ0423020.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIK
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACG8M1_002352"
     CDS             complement(4894..5613)
                     /locus_tag="ACG8M1_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0423021.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACG8M1_002353"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACG8M1_002353"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFQ0423022.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACG8M1_002354"
     CDS             7164..8561
                     /locus_tag="ACG8M1_002354"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0423023.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACG8M1_002355"
     CDS             8642..9082
                     /locus_tag="ACG8M1_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0423024.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACG8M1_002356"
     CDS             9229..9555
                     /locus_tag="ACG8M1_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0423025.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACG8M1_002357"
     CDS             9556..10305
                     /locus_tag="ACG8M1_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFQ0423026.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACG8M1_002358"
     CDS             complement(10331..10741)
                     /locus_tag="ACG8M1_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0423027.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3536 a         1947 c         2291 g         3374 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagttttgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaatt
//
LOCUS       DAZKNV010000072        11015 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000072 DAZKNV010000000
VERSION     DAZKNV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.073"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(221..706)
                     /locus_tag="ACG8M1_002359"
     CDS             complement(221..706)
                     /locus_tag="ACG8M1_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFQ0423028.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    796..1141
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1186..1827
                     /locus_tag="ACG8M1_002360"
     CDS             1186..1827
                     /locus_tag="ACG8M1_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0423029.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            1846..2481
                     /locus_tag="ACG8M1_002361"
     CDS             1846..2481
                     /locus_tag="ACG8M1_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0423030.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2499..3314
                     /locus_tag="ACG8M1_002362"
     CDS             2499..3314
                     /locus_tag="ACG8M1_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0423031.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3633..5069
                     /locus_tag="ACG8M1_002363"
     CDS             3633..5069
                     /locus_tag="ACG8M1_002363"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0423032.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5258..7705
                     /locus_tag="ACG8M1_002364"
     CDS             5258..7705
                     /locus_tag="ACG8M1_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFQ0423033.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7935..9002
                     /gene="rlmN"
                     /locus_tag="ACG8M1_002365"
     CDS             7935..9002
                     /gene="rlmN"
                     /locus_tag="ACG8M1_002365"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFQ0423034.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            8992..9198
                     /locus_tag="ACG8M1_002366"
     CDS             8992..9198
                     /locus_tag="ACG8M1_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423035.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(9195..10298)
                     /locus_tag="ACG8M1_002367"
     CDS             complement(9195..10298)
                     /locus_tag="ACG8M1_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0423036.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            complement(10666..>11015)
                     /locus_tag="ACG8M1_002368"
     CDS             complement(10666..>11015)
                     /locus_tag="ACG8M1_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0423037.1"
                     /translation="EAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFE
                     DAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDE
                     WIYSSRKYINFDK"
BASE COUNT         3614 a         1882 c         2365 g         3154 t
ORIGIN      
        1 tccgatttat aatcgaaaaa agaagcattt ttatatatgc ttcttttttc gtagaatcaa
       61 taaatatgga tttggctaac tatggaagaa tactcgtatt agttttcagc gttcatacta
      121 gttgttacat tgtttgattg gccaaaagaa tttctgatat attttgtgct aaataaagaa
      181 aaagacgctt gaattgggaa ataagaaaac tactctatca ttacaaattt tcataaactg
      241 gcagatgttc taagtaaaca agtatctttt caaagtcgga aaaatccata atcaacgtag
      301 tggtattgat atttggatga aagcctacgg tatcttgacg atcaatagca gcatcgatca
      361 cgacttggat ttttttctct ttgtcgtgca tcaatgctaa tggagtcact gtacctgctg
      421 gaacgcctag gaggtcagga agctgttctt cagaaacaaa agataagcgc ttttctttta
      481 attgttcagc tagttgtttt aaatcggcgt gcttttcatc aggcaagatg acaagataga
      541 tttgttttcc ttttcttgat ttcaataata gattttttac ttgcggacca ggtagggaaa
      601 aagggacatt tttgactgac gtaatcgcag gatgatcgac tttttgaaaa gagataccca
      661 gtttttttag tagttcataa gcttcttgtt cggttgcacg actcatcgcg catcaccctc
      721 ctttttttat tagtgtatca taaaaaagag ttgacaaatg aaaaataatc atgtaaatta
      781 cacgtaaagt taaaacaaat gacatcgaaa agaagagtag ccgttaggtg tttttagaga
      841 gtctctggtt ggtggaaaga ggcagcagtt aaccgtgaaa cacatcttgg agtcgatttt
      901 ctgaagcgta tagtaggaaa atccggggag cccgttacag ctgcggtcgt tgctagatga
      961 ccagataagg ctggcttttc cgtgaggagt cggtaaaaaa aggtggaacc acgtgattaa
     1021 cgtcctttga tcttcggatc aaaggacttt ttgttttcat ctgaacggca acgactgtgt
     1081 gaggtttttt ctgcaaggaa aaaataaaca gaggtggaac cacgtataat acgtcctctt
     1141 ggcatttgcc aagaggattt ttttatttta aaggaggaaa agaagatgga gtatttgatt
     1201 gaagttatgc cgcaattatt agtaggagca ctcacaacat tgaaattatt tttatttacc
     1261 ttgattggct cattaccatt agggattgtt ttagcattag gattgtcttt gcattttaag
     1321 ccgctacgct acttgcttca aacatatgta tgggttatgc ggggaacacc gctgttgttg
     1381 caactgattt ttatttttta tgggttgccg acgattggga tcgtttttga tcgtttcgaa
     1441 gcagcactca ttgcctttat cttaaactat gcagcttatt ttgcagagat ctttcgtgga
     1501 gggatacaat cgattcctca aggtcaatat gaagcagcgc aagttttgca attaagtccc
     1561 tttcaaacgg tgacgaaaat cgtcatccca caagtgacaa agattgtttt accttctgta
     1621 gggaatgaag ttatcaactt ggtcaaagat tcttccttga tctatatatt aggtttaggt
     1681 gacgtaatgc gtgctgggaa aatcgcgatg gaacgcgacg cgactttact gcctttgcta
     1741 ggcgtggcaa tcatctatct tacattgact ggtattctaa caatcataat gaaacaagtt
     1801 gaaggaaaat taaattatta ccgctaactg ataggaggaa gaaatatgat tgaattgaag
     1861 aaagtgaaca aagcatttgg tgaaaaaaaa ataatcaaag atttgaatct aatcattcca
     1921 gatgggaaaa cattagctat cgtaggtcct tccggtggcg gtaaaaccac gcttttacgt
     1981 atcttggctg gcttagaaag ttctgacagc ggagaatttt atttagacgg tgtaccgttc
     2041 aacccattcg agcttaaaat gaaagaacaa gttgtaggag tcgtattcca agacttccag
     2101 ctatttccac atctgaatat ttttgaaaac attaccttag caccaaaaat ggtattgaaa
     2161 cagacaaaag aagaatacac caaaaaagca gaagaattag cggcttcatt agggattagt
     2221 gatttattga atatctatcc ttatcagctt tctggcggac aaaaacagcg ggtagcgatt
     2281 gccagagcat tggctatgaa tccacgggta ttggcttatg atgaaccaac aagtgcttta
     2341 gatcctgaat tacgccagca agtcgagcgt ttgatcctat cattgaaaga agatggggta
     2401 acccaaatta ttgtcaccca tgatttagta tttgcagaaa atgtcggtga tcaattacta
     2461 aaagtttccc caattcatta agaaaggaga agatagagat gaaaaaaacc agttttctat
     2521 tcgctttgat cgcaggtctt cttctttttg caggctgttc gaacaaaaaa acttcagcag
     2581 ataattgggc gactatcaac gaagagaaaa aaatcgttat aggtttagac gatacatttg
     2641 ttcctatggg atttagagat aaagacggga agctcacagg atttgatatt gatttagcca
     2701 aagcagtctt tgaacaatat gggattacgg tagactttca gcccattgac tggtcaatga
     2761 aggaatttga actgaacaat ggaacgatcg atttgatatg gaacggctat tccaaaacgc
     2821 cggcaagaga aaagaaagtg caatttacaa aaccttatat ggaaaacgat caagtgctga
     2881 tcacacctaa agaatcagga atcacaaact ttggacaaat gaataataag agattaggtg
     2941 cgcaaaatgg gtcatctggt tatgatgtat ttacgaaaca accagaagta ttaaaagaga
     3001 tagtcaaaaa ccaagatgct gttttgtatg atagttttaa tgaagcattg atcgatctga
     3061 aaagcagacg ggtcgatggt ctgctgatgg ataaagtata cgcagactat tatttgaaac
     3121 aaagaaacga actagaagac ttcaacataa caaaaggttc ttatgagagt gaggattttg
     3181 cagttggtgc acgcaagtca gatagtacat tagtgaaaaa aatcaatgaa gccctagatc
     3241 aactagagaa aacaggtgaa ttccaaaaaa tatccgataa atggtttggc gaagatgtta
     3301 cgccgagaaa ttaacaaata ggggactgtg acaaaagacg tgtcacagtc cctttttccg
     3361 aataaacagt gttctcctgc caactccttg tgactcggag ctgaatggca ggctcacaac
     3421 ctcttggtaa acggtgttca aaagccagtt tttcggtatt aagccaaatt tatgcaaaaa
     3481 tgtagaaagc cattttcaca aaatttttct tactactcga aactaagcga ctttttcaca
     3541 acctccttta cataatttta ttttgttgtg gaaggggttt cgtgttattc taaaagagga
     3601 acgattgaag gttataggaa aggaagagat gaatggaaca caaagaactt acctcatttc
     3661 caaaagattt tctgtggggc tctgcttctg cagcgtatca agtagaagga gcttggcaag
     3721 aagatgggaa aggagaatca gtctgggatc gatttgtacg gatacctgga aagacattta
     3781 aaggaacgaa cggtgatttg gcagtagacc actatcatcg ttataaagaa gatattgctt
     3841 taatgaaaga acaaggtctg aaagcttacc gcttctctgt agcttggaca cggatttttc
     3901 ctaatggacg aggagaagtc aatcaagctg ggctcgcttt ttatgagaga ttgatcgacg
     3961 aattgattga aaacgatatt gaacctatgt tgactttata tcattgggat cttccacaag
     4021 cattgcaaga tgaatataat ggttgggaat cacgtcagat cattgaagat ttcactcatt
     4081 atgcagaaac attatttgag gcattccgcg ggaaagtcca ttactggatt agtttgaatg
     4141 aacaaaatat cttcacttca ttaggttatt tgttagcagc acatccgcca ggtgtgacag
     4201 acccgaaacg aatgtatgaa gttaaccata ttgctaattt agcaaatgca tctgtcatca
     4261 ataaatttca cgagttagaa atgcctggaa aaatcggacc aagctttgcg tatacgccaa
     4321 attatccaat tgacagtaat cctgaaaatg ttctggctgc tgaaaatgca gaagacctga
     4381 tggccaatta ttggatggat gtctatatgt ggggaaaata tccgattgct gccatgaggt
     4441 tcttagaaga aaaaggatgg gcaccaacga ttgaagctgg cgatgcagaa ttgctagaat
     4501 ctgctaaacc agattttctt gggatcaatt actatcaaac ggcgacgaat gcattcaatc
     4561 cattaaacgg agttggtgct ggaaaaatga atacgacagg aaaaaaaggt tcatcagaag
     4621 aaactggagt tcctggaatg tataaaaaag ttgagaatcc atttgtcgaa cgaacaaatt
     4681 gggactggga gattgaccca gaaggattaa ggatcggact gcgtcgtatc acaagccgtt
     4741 accgcatgcc ggtactgatt acggaaaatg gcttaggaga gtatgacaag ttgacagaag
     4801 ataaacaaat ccatgacgac tatcgaatca attacttaca aagccacgtc aaagccatca
     4861 aagaagcaat ttcggatgga gcagaagtcc taggctattg cacctggtct tatacagatt
     4921 tgcttagctg gctgaacggt tatcaaaagc gatatggatt tgtatatgtt gatcaagacg
     4981 aaacacaaga aggatctttg gaacgatata agaaagacag ttattactgg taccaaaaac
     5041 tgattgaaga aaatggagag aacctttagt tcacatactt aaaacaagaa ggtacggctg
     5101 gatatggccg tgccttttct tgataaaatc atttagaaat taagaaaaac tgtaaaataa
     5161 gctgaaaaat gaaagaaagc gtcagttctt tcaaacaaaa ctttagttcc cttacttttt
     5221 tttgtataat gaaacttgat gaaatgaggg ataataaatg gcacaaaaga aacggcctac
     5281 taaaaaaagg aaaaagacga aaaaaacgaa aaagcaaaaa cagcagcagg aacaaatgct
     5341 gacgattggt gttgggtttg ccttgatttt atttgctgtc ttcggctttt taaaattagg
     5401 ttttttagga atattgattg caaacggctt tcggatcatt gcaggaaata cttaccaaat
     5461 cctctgtctt ttattagccg tattaggatt ttggattgtc attaagaata cagagttttc
     5521 aattggtaaa aaccgacgct ggtttggcgg catactcttt tatttcggta tcttattatt
     5581 gttacatgcc catttatttg gcaaactcca tactggggaa ccaaatatca tggggacgac
     5641 atgggatttg ttagccagtg atataaaaca aagtcaagta gacaataacg ttggtggtgg
     5701 gatgattgga gcaatccttt atcattttac ttacttcttg attgcacagc ctggaagtta
     5761 tttagcagca gtgctattac tggcaggagg agcattcctg ttcagtaatc tggaaggcta
     5821 tcagctgtta aatggtatcc aatcaattgg agaacgagta caggaattat tggaaggtga
     5881 tcctgccaag caagctcgaa agcaagcggc aaaggaagag agaatgaaac agcgcgcaga
     5941 agcgaaagaa gcaaggcgct tagctgcaaa agaagctgca gaaaaagaag ctgcagaata
     6001 tgagaagaaa aaagcggtga gccagcaaag ggaaaatact gctgatgaat ggcaggaacc
     6061 agaaaataca gagccggagc agctaagttt tgttccaatc gacagttttc aagaaaatat
     6121 ccatcctgcg aatctagaga aaccagtacc agatacacca aaacagacca atacagcaga
     6181 aggtttttca gatgagttgc cagaggatga cggtacctca ttagaatttg agattgaagc
     6241 agaacaggaa aatcaagact atgaattacc gacagttgat ttgcttgatt ctataccaac
     6301 tgtggatcaa agtgatgagt ataaaaaaat tgaaaaaaat atcggcgtat tagaacaaac
     6361 tttccaaagt ttcggtgtcg atgccaaggt cgtcaaagcc agcttaggac catccgtcac
     6421 aaaattcgaa gtccagccgg ctgtaggggt aaaagtaagt aaaattgtga acttaacaga
     6481 tgatatcgcg cttgctttag cggcgaaaga tgtccggatg gaagcaccga ttccaggtaa
     6541 atcactgatt ggtattgaag taccaaatgg aaagatcagt atggtttcct ttagagaaat
     6601 catcgaagca caaccaaacc acccagataa attactagaa gtacctttag gacgtgatgt
     6661 ttctggacgg gtacaaacgg ctgatctttc gaagatgcct cacttactcg tggctggttc
     6721 gactggtagt gggaagtcag tagcaattaa tgggattatc acaagtatat taatgcgtgc
     6781 taagccccat gaagtaaaac tgatgatgat cgatccgaaa atggttgaat tgaatatgta
     6841 caacggcata cctcatctgt tgacgccggt cgtgacgaac cctagaaaag cagcgcaagc
     6901 cttacaaaaa gtagtacaag aaatggaaga acgatatgaa aaattcgcgg caaccggagt
     6961 aagaaatatt tctggttaca atgaatttgt tcaacagaaa aacttggaaa acggaacgaa
     7021 acatccaacc ttaccattca tcgtagtgat cgtagatgaa ttagctgatt tgatgatggt
     7081 agccagcaat gaagttgaag atgcgattat tcgtttagcg caaatggctc gggcagcggg
     7141 gattcatatg atcctagcta ctcaacgtcc aagtgtggat gttatcacag gaatcatcaa
     7201 agcaaatgta ccttccagaa tggcatttgc ggtatcaagc ggtacagatt ctcggacgat
     7261 cattgattct aatggggcag aaaagctctt agggcgagga gatatgctat tcttgccaat
     7321 gggtgagaat aaaccgatcc gtgtgcaagg agcattcatt tctgaccacg aagtagaacg
     7381 ggtcgttcaa tttgttacag atcagcaaga agctcattat gaagagaaaa tgatgccgac
     7441 agatgaagtt gaaacgacag gtgctccaga acagccacaa gatgagctgt ttgaagaagc
     7501 aaaagcactt gtcgttgaaa tgcaaacggc aagtatttcc cttctccaaa gaagatttcg
     7561 gatcggttac aaccgagcag cacgtttagt agatgaactg gaagctcatg gagttgttgg
     7621 cccgtcagaa ggaagcaagc ctcggaaagt attcattgag caggaagaaa catcagaaac
     7681 gttgccggac gataatgaca tgtaaaactt gtgtgatgaa gggttgaaaa acgaataacc
     7741 aataaaaaga caaggcatga tgataccaaa agaaaaaatg gtttttttcc atcttttcta
     7801 atacggtatg atgtcttgtc tttttagttt ttgtgagatt aaagttctat tcgatttatt
     7861 tgtgaagtat tgcattaagg aaatgaatca tgtatagtat gtagcgaaac tttgagaaaa
     7921 agagggaaaa tactttggaa aaacagtcca tttatggctt gacgaatgaa gaattaatca
     7981 attggtttat agaaaacggc gagaaaaaat tccgagctgc ccaagtttgg gaatggttgt
     8041 atcaaaaacg tgtaagtaat ttcacagaaa tgacgaatct atcgaaacaa ttgatcgaaa
     8101 aattatcgga gcattttatc atcaatcctc taaaacagat ggtcgtccaa gaagcttcgg
     8161 atggtacagt aaaatatttg tttgaactcc ctgataaaaa catgattgag actgtactga
     8221 tgagacaaga atatggcttg tcagtttgtg tgacgacaca agtaggatgt aatatcggct
     8281 gtacgttttg tgcaagcggg ctgctcaaaa agaaccgtga tctgactgct ggagaaattg
     8341 ttgcacagat catgatggtc caacattatt ttgatgagcg caatcttggc gaacgcgttt
     8401 cacatgtcgt tgtaatgggg atcggtgagc catttgataa ttacgacaat gtaatggact
     8461 ttttgcatat catcaatgat gccaaaggat tggcaattgg tgctcggcac attacagttt
     8521 ccactagtgg attagcacac aaaatcaagg aattcgctaa taacggcttg caagtcaatc
     8581 tggctatttc cttgcacgcg ccgaataatg aggtgcgaac atcgatcatg cggatcaacc
     8641 gaagtttccc aattgagaaa ttgatggaag ctgtggatga gtatttagag aaaacaaacc
     8701 gtcgaatcac gtttgaatat atcatgttga atcaagtaaa tgatagacca gagcatgcgc
     8761 aacaattagc agatctatta aaagataaga aaaaattagc atatgtcaac ttgattccat
     8821 ataatccagt cagtgaacat gatcaatatt ctcgcagtcc aaaagctgat gtattgagat
     8881 tttatgatgt attgaagaaa aacggcgtaa actgtgtgat acgtaaagaa catggtacag
     8941 atattgatgc agcttgcgga caattgcgaa gcaagcaaat gaaaaaaaca gttgccaaat
     9001 aatcgtatcc tactcgtttt ttcaattacc ataaaaggag cagttttctt aattaaggaa
     9061 ctgttcaact taaataagag aaaagattct atagcgaaag ctataaagct ttttttgaca
     9121 agaaaaaccc tcatcaagca aagaaatgtc ctcaatttga tgacagcctg cttgatgggg
     9181 gttttagcaa ttatttaact gattttctta tatccttgct ggctttcttg tgtagcatga
     9241 taagtttcta cgtcaagaat ggcctgttta aatttttctc gggtgatttc ataaggcaca
     9301 tgtttaatat catttgttgc catggcttta tctaagattg cttctaaatc ggtcgtgaca
     9361 ttgagattca tgtcggttaa cgatactgga agttggttct ttttcataaa cacatagatt
     9421 ttatcaaaca aatcgaactg ctgatccatc atcaataagg tcagtacacc ataactgaca
     9481 gatgctccgt gaaggtatcc ctccattttt tctagaacag tcgtaccgta atagaatgag
     9541 tgtgccatag cagaattata gttattgtta actaaaacag aaaccaatcc ggtagtaaca
     9601 atgatatccg aaacgacttg ttcaattgca tatgagggac gatcgtcggc actatctttc
     9661 aatgcttgcg taccataagt caagagacga tcaatgcaca tttttccgat ttggattcct
     9721 aatctatccg tgtagcctag atcatcgcca cgagcagaaa aagtagattc gacttctttg
     9781 gataaagcat cgccaatacc tgcccataag tatttatcag gtgcttcggc aataattgct
     9841 gtatcaatga aggtgtgtac aggtggtttt gaaggaaaga agagtccgtc cattacgcct
     9901 tcttcgttat agatgacaca taccgcagtg acgggcgaac agttcgaacc aatagtggga
     9961 aaggtgaaga ctggtttagc tagtttttca ccaatgactt ttacagtatc gcaagcacgg
    10021 ccaccaccga ctgcaaacag gacgtctgct ttttggacac tttcatgctg gatcaactgt
    10081 tcaatatttc cataagttga attacccccg taccagagac tggcgacaac ctctatttcc
    10141 tgtgtcaaag ctacttttat tttgttttct gcctttgaaa gtgcagtctt ccctccaatc
    10201 agcactactt ttgtcccata ttctttgacg attccatttg ctttttcata cgcatctgtt
    10261 ccaatggtat aatttggtaa gaaaacactt tgactcatat tcatttcctt ctttcttcgt
    10321 tgaaacgggt taaaatttta aagagtgatc gatctgactg cggctgtaga tggagtagag
    10381 gtgaacctaa gacaggataa gtgatgaata aggtggcatg aacaccttga aatcatcaat
    10441 aagtatccta aaaacgaaca agtacaaaaa cattgaaaac gacaataatg aatttttgtt
    10501 cctcttagta tttctaccga ttccctttgc ttttttgtaa ttatctaaaa attctaaaaa
    10561 ttaagattat tatatgaaaa caggttttat ttgtcaattc ataattggtt tttttagtca
    10621 agtccagact cctgtgtaaa atgctataca atgtttttac catttctact tatcaaaatt
    10681 gatgtatttt cttgaagaat aaatccattc atcatgtagg tccataagaa cggctccaat
    10741 taagcgattg gctgatgttt gattggggaa gatgcgaata atcttttctc ttctgcgtac
    10801 ttcttgattc agtcgttcaa ttagattggt actctttagt cgattgtggg aatttccttg
    10861 tacggtatat tgaaaggcgt cttcgaatcc atcatccaat gatgcgcaag cttttgaata
    10921 ttttggttga tcgatataat catgaatcaa tcgattttta gcctcacgcg ctaagttaat
    10981 atctgtgaac ttaaaaattc ctttaacagc ttctc
//
LOCUS       DAZKNV010000073        10718 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000073 DAZKNV010000000
VERSION     DAZKNV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.074"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(261..1109)
                     /locus_tag="ACG8M1_002369"
     CDS             complement(261..1109)
                     /locus_tag="ACG8M1_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0423038.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1273..2175
                     /gene="gnd"
                     /locus_tag="ACG8M1_002370"
     CDS             1273..2175
                     /gene="gnd"
                     /locus_tag="ACG8M1_002370"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFQ0423039.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKRTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2177..3178
                     /locus_tag="ACG8M1_002371"
     CDS             2177..3178
                     /locus_tag="ACG8M1_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFQ0423040.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3175..3459
                     /locus_tag="ACG8M1_002372"
     CDS             3175..3459
                     /locus_tag="ACG8M1_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFQ0423041.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3492..4289
                     /locus_tag="ACG8M1_002373"
     CDS             3492..4289
                     /locus_tag="ACG8M1_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0423042.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4303..5136
                     /locus_tag="ACG8M1_002374"
     CDS             4303..5136
                     /locus_tag="ACG8M1_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0423043.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5154..6011
                     /locus_tag="ACG8M1_002375"
     CDS             5154..6011
                     /locus_tag="ACG8M1_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0423044.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            6033..6542
                     /locus_tag="ACG8M1_002376"
     CDS             6033..6542
                     /locus_tag="ACG8M1_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFQ0423045.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6579..6980
                     /locus_tag="ACG8M1_002377"
     CDS             6579..6980
                     /locus_tag="ACG8M1_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423046.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7092..7445
                     /locus_tag="ACG8M1_002378"
     CDS             7092..7445
                     /locus_tag="ACG8M1_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423047.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVEADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7479..7922
                     /locus_tag="ACG8M1_002379"
     CDS             7479..7922
                     /locus_tag="ACG8M1_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0423048.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7939..9024
                     /gene="uxuA"
                     /locus_tag="ACG8M1_002380"
     CDS             7939..9024
                     /gene="uxuA"
                     /locus_tag="ACG8M1_002380"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0423049.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            9017..9730
                     /locus_tag="ACG8M1_002381"
     CDS             9017..9730
                     /locus_tag="ACG8M1_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0423050.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(9937..10086)
                     /locus_tag="ACG8M1_002382"
     CDS             complement(9937..10086)
                     /locus_tag="ACG8M1_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423051.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            10482..10682
                     /locus_tag="ACG8M1_002383"
     CDS             10482..10682
                     /locus_tag="ACG8M1_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0423052.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3592 a         1693 c         2315 g         3118 t
ORIGIN      
        1 ttttttagaa aataagaaac aaaaataata aaaaaaagaa aagataaatt ttttactact
       61 gtatactaac tttgttatcg catctaacaa gtaactcgaa taataccaat acaaccttct
      121 ccaaagatgc gatgacatac gttctaaccc accgactatt gatgttctgt accacccttg
      181 cagaaccaaa aaagccacta ccaaatattt ggtagtggct ttttttgttt tatggatttt
      241 tcgctttttc tgttatggtg ctattctttg atttcagaaa tagtatgtcg aactttagcg
      301 atagaacgac gtgattcttt ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa
      361 atgcttagtt gagaaatacg ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa
      421 atagaaataa aaacgacatc gccaagttta gcaagggaag aattagcttg gctagtaata
      481 acgattgttt ttgctccagt ttttcttacg gtttcagcaa tatggattgt ttcttttgat
      541 tgccctgtgt gagaaatcaa aacagcacag tctttttccg tcaataaaga agcttccatc
      601 aattgaatat ggtaatccgt gctgtgagaa gttgcgatag gggaacgcaa aaatttatga
      661 taagcgtcag ttgctacaat ctctgaaccg ccaacaccga aaaaatagac acgtttagat
      721 tcattgataa tagtagccgc tttttttaga tccttttgtt gtaacaactt ttttgtgtca
      781 tttaaagttg aaatactaga ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt
      841 ttctgaatat tttcgtggat agaaatagca gatagatcat tttcttggat caacatggcc
      901 attttaaaat ctttaaatcc attataacca agtttttttg taaattgaaa aaaagtagag
      961 tcagcaatgc ccagttcact tgctaaattg ctaataggac tatgacttac tttgcttgga
     1021 ttttctaaaa tataatcggc gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt
     1081 ttgatttgta gtcttatgga gacgctcatg agaattcctc attttcataa taagattatc
     1141 attttttccg ttctcattaa tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa
     1201 aatatttttg taaaatctat ttacaaaaaa atttttttgt ataatgaggg tataagaaat
     1261 ggaggcgcta tcatggaaat tggtgtaatt ggtttgggaa aaatgggatt gaatttagct
     1321 ttaaacttaa aagagcacca tcacaaagta caaggactcg acatttcaag tacagctgtt
     1381 agtcaggcaa gagaaaatga cattcctgct tatcaagaga tctctgaatt tctagctact
     1441 tttgagcaga aaaaaatcat ctggttaatg cttcctgctg gagagataac cgaaaacatg
     1501 ttaagaaaac tttttccaaa actcggacca ggagacatta ttattgaagg cggaaactct
     1561 tattataaag attcaatccg tcgagcagaa gagtttcaga aaaatgaaat cggttacttg
     1621 gattgtggga cttctggagg aatcgaagga gcacgacatc aagcctgctt aatgattgga
     1681 ggagataaag aaacttttct atccgtggaa caattattca aagatgtagc aattgaaaga
     1741 ggatatctgt atgctggtgc atccggaagc ggacacttct tgaaaatgat ccataatgga
     1801 atcgaatatg gaatgatgca agcaatcggt gaaggattcc aacttgtaca aaaaagtgag
     1861 tatgcttttg acttggaaca agtcgcacgt gtttggaatc atggttcggt gattcgcggc
     1921 tggctgatgg aaatcatgga agatcagtta aacgaacatc ccaatttaag taattatcgg
     1981 ggaatcgttt ctgcatcagg tgaagcaaaa cggacggttg aaacagcgct agaaatggct
     2041 gttccagttc cagtaattgc aactagtttg ttcatgagga atctttcaca ggaagaagat
     2101 agtttttcag caaaagtagt ttcagcacta agaaatgggt ttggcggaca tgaaatagtt
     2161 gaaaagggtg agtaaaatgc cagattatca tatagcaatc gttaattcca gcagtttcgg
     2221 aagagtcttt ccacaccact tggaaagatt aaagtcagtt ggagacgttc atttctttac
     2281 tgttgatcaa gagattccag gaaaagaact agcggagtta cttaaaggat tcaatatcat
     2341 tattgcaagt gttacgccat tttttcgacg agattttttt gaaaacaaag atgaactgct
     2401 attgatttcc cgacatggta ttggttacaa caatattgat ttaaaagcag caaaagaaca
     2461 ccagacaatc gtatctatca tacctgcttt agttgaacga aatgctgtag cagaaaataa
     2521 tataactaat ttgttgtcca tgcttcgacg cacgacacaa gcacaagcaa gagtcaagga
     2581 cgatcgatgg gaagatcggg cggagttcgt cggtaggacg ctgtttaaca aaacagttgg
     2641 tgtgattggt gcaggaaata ccggaagcgg agtaatcgaa attttgcgta acggttttcg
     2701 ctgtgatgtt ctagcttatg atccttacaa atcagattta tacatcgaaa gctttggtgc
     2761 aaaaaaagta gaacttcaag aattactgga acaatcagat atcatttgtt tatgtgcgaa
     2821 tttgacagaa gagaactatc acatgatttc tgataaagaa gtcgatcaga tgaaagaaaa
     2881 tgtttatcta tctaatagtg caagaggcgc tctagttgat gaagaagcga tgattaatgg
     2941 tctgaaaagc ggaaagatcg caggatatgc cacagatgtt ttagaagaag aaccgggacg
     3001 tcaagatcat ccgtatttag cgtttgaaca agtagtgatt acgccacata tatcggccta
     3061 cacaagggaa tgtttagaag caatgggtga aaaatgtgtc agagatgtcg aacagatcag
     3121 tcagcacctt cttcctgaac gttctgtcca gacaaagagc aactatataa aaggatgatg
     3181 aagaaaatgg tgaacggttt aaaagtgaaa acaggccctc aattttattt atatgaagaa
     3241 ggtggtattt caaaagtttc tgatctcttg aaatcatacg gcgcgaaaag agtactggtc
     3301 acccacggaa cggtatcatg ggaaaaggcg ctacctaaat tagtattttt gaatgacgaa
     3361 acgattcaat ttttttatca tcgttattct ggagaatgta gttatgctga agccagacga
     3421 atagctacaa tcatcaaaaa aatgaaatcg atttcgtagt tggcgttggc ggaggaaaac
     3481 tgaccgatct agtgggttat agtgccaatc ttgcaagaat cgatttcgga gtcatcccta
     3541 ctttagctag taattgtgct ccatggacac ctcttgctgt catgtataag gagaatggac
     3601 aagcagaagg gaaaacagaa cacttttaca gacaagctgc tttttttata acagatcccc
     3661 aattagtgat tgattcccct gttccatatt tcattgccgg gttagcagat acactagcaa
     3721 aatggtatga atctgagctc atcttagaac aagatttttt gcaagatgaa tcatttttga
     3781 agctagcaca agatactgcg aagatctgca aagaagagat tttgaatcat tctgctaaag
     3841 caatccaaga tatggcacaa agaaaactga catcggagtt caaacagctt tcagagatta
     3901 tctttgctgt tgctggttta gttggaggat taggagataa atacgcaaga aatgtggcag
     3961 cacatgctat gcatgacgct atcagtaaat atattccgga aagccatcgt tttctacatg
     4021 gagaaaaagt agcgtatggg attttctatc aactggcact agaaggtcgc tgggaaaaaa
     4081 tagacgagtt atatcctttg tatcgggaat tagaactgcc ggtttctcta gaacaaatgg
     4141 gattatttcc gaaagataaa cagataatag ataaaatggc tgaatttatt gattcgaaag
     4201 agaaagtgca tttgattcct atagaggtaa cacagaaatc actgatacag tcaatgatgg
     4261 aactggaagg ttatatcaga aagatctgaa ggaggaggac acatggaaac attaagtgta
     4321 gtacaaagtt tgttgattgc tttatgggta gccgcggtta tgtcccgctg gttaggtgga
     4381 ggagccacgt tgaccttacg tttttctcct ttgatgactg gattagtcgt cgggttgatc
     4441 atgggggaag ttgcacaagc gatgattgtt acagccgctt tgcaaatgat ttatatgggg
     4501 gttttttctc caggaggatc aatgccagct gaaccatcta ttgcagcagc tatcgcagta
     4561 ccagtcgcat tattagggga tctgtcgcca gaagcagcga ttgccgttgc ggtgccagtc
     4621 ggattgctcg gaagttactt gtatcagttt cgttttttca tcaatacttt tttaggtaaa
     4681 tatacagaca aagctgtaga agatttgaat acaaaagcta tggcccgatc aattattctt
     4741 tatccaacgg ttgcctcatt tttattattc gttccgcttg ttttcattgc tttatattta
     4801 ggggcgccat tgatcgctga tgtaatcaaa gctttagagg gaacagtcgt tatccacatt
     4861 cttgaagtag taggtggagg gttagcggca atcggtatcg cgacaactgt atacgttatc
     4921 ggtcgaaaag attatctggt ctttttcttc cttgcttatt ttatgagtgt tgttttgaaa
     4981 tctttagata ttacgatggt tacttatgcc atttttggga ttattatcgc tttgatcttt
     5041 gtccagtcgc aaaaagggaa acaagtacag cctgccacaa gcaataacaa ttcagcatct
     5101 tttgatgacg aagatgacta tgatgacgga ttttaattta ggaggaatgg gaaatggctg
     5161 aaataatgga taatcaaaca ggtgctcctg aagaaatcac gaaaaaagat gtaacaaaag
     5221 cctatctgag atggcatttt gcaaacgaaa ttcctcactc ttttgaacgt tacttggcgc
     5281 catcactact atacggaatg atgccaatct tgaaaaaact ttataaagat gaagactctt
     5341 taaaagcagc atataaacgg cagttactgt tcttcaacac tcaattaagc tggggtggcg
     5401 gtgtgattac tggcctaatg tcttctatgg aacagcaaag agcagaagaa gagtatgaag
     5461 aaaaagagat cttgatgcag gatgacttga tgtataacac gaaagcggga ttgatggggg
     5521 cactagcagg aatcggagat gcaatcgatt caggaaccgt ccaatatatt tttatcgcaa
     5581 tcgcggtacc ttgggcacaa cagggaagtc ctttaggcgc actttttcct tttatctgct
     5641 ttgggttgta tcaggtttta ctaggggtat ttttcgcaag acaagctttc actatgggcc
     5701 gtaatgctac aggcctaaag caaaacactg gtgttcagac agcgattgaa atgctatcag
     5761 ttttagggtt gtttatgatg ggggtgcttg cgggaaacta tgtaaaagta gaatcttcat
     5821 tgaaatttgc gatatccgga cgtgagtttg ttatccagga aattcttgat caaatcgtgc
     5881 cagggatatt acctttagct gtcgtaatgg gtgtgtactt gttctatacg aaaaaaggat
     5941 tgaaagtcac acaagcatta ttatggctga ctggaatatt aattgtgcta gcaggaatcg
     6001 gtattttata aaaagaaggg aacgtgaata agatgggtgt agtcaattta gcgcgtgtgg
     6061 atgagcgttt gatccatggg caagtaatgg taacgttatc tcaaaaaagt ggagtgaatt
     6121 ccatttttgt tgtagacgaa gttgtagcaa aagataaatt tatgagagat ctttacaaaa
     6181 atgcaggaag ccgtacagga caaaaaacaa ttgtcattac accagagaaa gctaaattct
     6241 attgggatga atatcaattt aaagaataca attgtatttt gatcgcaaaa acagtccaaa
     6301 cgatttacga cttagtaaaa cacggaatcc ccatggaaga attgaatatt ggagggattg
     6361 ctcaaaaaaa tcctgataca gatcttttag tgacgaaatc tgtttattta aataaatcag
     6421 atgctgaaaa attgaaagaa atgaatgaac aatatggcgt aaagaatatt tattttcaag
     6481 ccactccatc tgcacctaaa acaggattaa aagatgtatt gaacaagttt gatttgtcat
     6541 aaacaaatgc ttagaaaaaa gataaagagg gcgaaaaaat gaagaagaac gagctgtttc
     6601 gtgattggga atttcgttat cgctatattt accgtaagcg ccgtacaaaa aagagtaaac
     6661 agcgttttct ttcagcatta gtatcagata tttacagtat gagaacagat gtgacagtca
     6721 ttgcttacga tacgctagcc taccgatcaa aaaatattta tgttggagat atcgaaaaag
     6781 cagagaaagt tatctgtact tattacgata cacccgttca tgcattagga agttatttca
     6841 tgtttgattg gaaagaccaa aggaaaaaaa caatctactc tatattattg tccttcattt
     6901 tgttgttcag tttaggttgg tggggaatga tgatatataa caaaaatcct catcacgtat
     6961 tcgatctgct atccgtataa acaggtatca ctgtactagc atttgggagc tactttttct
     7021 tattgggaaa agcagctcgc ggatggccta gcagacaaac ttttattcga aatacttcat
     7081 ccatattaac gatgctagaa atgatccgta cgattgatga tccgagtgta gcgtatgcgt
     7141 ttgttgatga aggctgttat ggagaaaagg gcttagacag cgtgagatcg ggtatgaaaa
     7201 aagaggctat tcttttttat ctagactctg ttgaggcaga tacaccgcta cagttttcgg
     7261 gaaattattt ttcaaataaa gaacagtggc tgaaacaagt tgataagttg aaagaaaaaa
     7321 acgtcaatta tatttttagt gcaagaaaaa agcaagcgca gttcttctat ttgaccaaaa
     7381 cagatttacg agggaaaaca tttaattggc aaaatgccaa tcagattatt gctctttttc
     7441 gataagtaaa aagtgcaaaa caaggagtga gaagactaat gttggaaatc atgatcgtta
     7501 cacatggtaa gttgagcgaa ggactgaaag atgcggcgga agtaattgtc gggacatcga
     7561 gccatattga aacaatgtgc ttagagtctg gggaggacat ccaaacattc ggagagaagg
     7621 tcaaagaaaa attaactatg atcaacacag cagaacccat gctagtattt gttgatctaa
     7681 ttagcgcaag tccgtacaat caagcgctct tggcagtcaa tgaactgact gaagaaaaga
     7741 aagcagccac ttatgtcata gggggcgtga atctgccaat gttgttagaa gcaatcaatc
     7801 atcagatgct tcacacaccg atagaagaag cggtggaaca aattgtcaaa caaggaaaag
     7861 ataatttaac tgtttggcat gcttcagcgg aagaaaaaaa attagatgag gacgattttt
     7921 agaaggaagg ctgaaaagat gaagtgggga tttagatggt atggtgaaaa aggggattcg
     7981 atcccattaa aatatgttcg ccaaataccg ggaataaatg ggataattgg aactttgctg
     8041 actaaaatgc ctggagatgt ttgggagatt tcagaaattg aggagttgaa agcatctgtt
     8101 gagagccaag gactggaact gcttggaatt gaaagtgtag cgatccacga tgcaatcaag
     8161 gcagggacag atgaacgaga ttactatatt gataactata tacgaacaat caaaaacttg
     8221 tctcgatgtg gggttcgatt gatttgttat agcttcaaac caatttttgg atgggcgaaa
     8281 actgatttgt ttaatgaaaa caacgatgga agctattctc ttttatacga tcagaaaatc
     8341 gtcgatcaga tggagccagg agaaatgtat caattgatac acagccagtc aaagggattc
     8401 aaattgccgg gttgggaaga agaacggttg aaaaaattcg ctcagctgga aaaactgtat
     8461 gaaggaatga ccgaagaaga attatttgaa aatctgactt attttttaga aaaagtgatt
     8521 ccagtgtgcg aaaaagcaga tgtaaaaatg gctatccatc cagatgatcc gccatgggaa
     8581 ctttttggtt ttcctagagt gacgaaaaat cttggcgact tgaagaaaat tctaaatgca
     8641 gtagattctc catataatgg actaacgctg tgcacaggat ctttaggggc aaatccggaa
     8701 aacgatttag ttgaaatcat ccatgaggta ggttcgcgca tccattttgt ccacttcaga
     8761 aacgtggagt ttttaggaga aagaaagttc aaagaaacgg cacatccctc tacagaaggc
     8821 tcccttgata tgtatcatat tatgaaagcg ttggtgcaag aagggttcga cggtcctata
     8881 cgccctgatc atggtagaac cgtgtggggt gaagtggcta tgcctggata tggcctgtat
     8941 gatcgtgcaa tgggactcac ttacatgcaa ggtctatatg aggcgataag taaggaaaaa
     9001 ccactgggag agcattatga ataaaatcaa gctcttcatc tttgatatgg atggcctttt
     9061 attagaaact ggacgtttag cttatcgtgc ttatgtaaaa tcagcacaaa agtatgatta
     9121 tgaaatgcgt aaggaagtct attatttact aactggccaa acagaaatgg cgataagaga
     9181 acaaatgggc attttgtacg gagaagatgt tccatatatc aaatggcgag aagcaatcaa
     9241 tcaatataaa gaaaaaatcg tgaaagaaga taagagagta tatacgaaaa aaggagcaga
     9301 agaaatttta tcttttgcaa aagaaagagg aatccataca atcgtggctt cgtctaatac
     9361 acgggtaaaa gtagaaatgt atttaaaaat ggaaaatcta tatgccttgt ttgatcaaat
     9421 catttcaggg gatgatgtaa aaaaaggaaa gccggaacca gagatctttt tgaaagcttg
     9481 ttcaaaaatg aatattcctc caagtgaagc acttgtattt gaagactcga ttgcagggat
     9541 cgaagcagca aggcgagcgg gcattttgtc ttttctcatc aaagatcatt tgatagggtt
     9601 gcccgatcat aatgggaagc ataagttgaa agtagatgta agtttatatg aatccaataa
     9661 agcagactat gaattttatg acctgcatca agcaaaacga tttttagaaa gtaaagggtt
     9721 gtatctctaa taaagaggac tattttctag tcctctttat ttattgtcct gcacgactga
     9781 gggaacagat gaaaaagaag taatttttta ttttgaagta tctaccttat ttgtagtgaa
     9841 caatttagaa caaacacaaa acgcatctac tgttatctac cagtagatgc gtttaaagag
     9901 aagaacgaga atcgtccata tgagggtttc cactccttat gcagattttt ttaattcttg
     9961 cactgcttgt tcgatcgtaa cacctgtcgc tacatgattg gtattttctt tgtcaaaaac
    10021 gacaaataga ttcaaatctg tatccaaggt tactcgatat tgtatatctt tgttatagaa
    10081 tgtcatagcc attctccttt ctttaaatac ttgctgaaag gcaacgaacg cgttgataac
    10141 gaaattccat ttataagtat accaccaatt gaaaggtttt catagttaag aaattttaaa
    10201 gtcaaaagtt gcagataaaa gcaaataaac aagaaaacaa aaagtgaatc aatcgcggtt
    10261 attcaacttt ttcttcgatt cgaagacaat agaagacaat gaattttata tttcattgca
    10321 ttatccttgt gttattagaa aaagcatgat atattaaatg agtaatctat tttgaaacgt
    10381 aatttgagcg atatatctac atagataaaa ctccttttgc ctatcaaata tttattgcaa
    10441 cgaaaaaacg tacattgata cgtatcagga ggaatttatt tatgaataac ggtacagtaa
    10501 aatggttcaa cgcagacaaa ggttttggct ttatcactgg tgaagatgga aatgatgtat
    10561 ttgcacattt ttcagctatc caaggtgacg gcttcaaaac tttagaagaa ggccaagcag
    10621 tgtcttacga tgttgaagat ggtcaacgtg gccctcaagc aacaaacatt gttaaagctt
    10681 aataaaaatt gacttttaac cgtcttttcg aaagaaaa
//
LOCUS       DAZKNV010000074        10670 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000074 DAZKNV010000000
VERSION     DAZKNV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.075"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            19..456
                     /locus_tag="ACG8M1_002384"
     CDS             19..456
                     /locus_tag="ACG8M1_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423053.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            551..1435
                     /locus_tag="ACG8M1_002385"
     CDS             551..1435
                     /locus_tag="ACG8M1_002385"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0423054.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1659..4826
                     /locus_tag="ACG8M1_002386"
     CDS             1659..4826
                     /locus_tag="ACG8M1_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFQ0423055.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            4894..5391
                     /locus_tag="ACG8M1_002387"
     CDS             4894..5391
                     /locus_tag="ACG8M1_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFQ0423056.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            5410..5874
                     /locus_tag="ACG8M1_002388"
                     /pseudo
     CDS             5410..5874
                     /locus_tag="ACG8M1_002388"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            5871..6629
                     /locus_tag="ACG8M1_002389"
     CDS             5871..6629
                     /locus_tag="ACG8M1_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0423057.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(6715..7455)
                     /locus_tag="ACG8M1_002390"
     CDS             complement(6715..7455)
                     /locus_tag="ACG8M1_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0423058.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            7516..8769
                     /locus_tag="ACG8M1_002391"
     CDS             7516..8769
                     /locus_tag="ACG8M1_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFQ0423059.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            9091..9318
                     /locus_tag="ACG8M1_002392"
     CDS             9091..9318
                     /locus_tag="ACG8M1_002392"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFQ0423060.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            9441..9767
                     /locus_tag="ACG8M1_002393"
     CDS             9441..9767
                     /locus_tag="ACG8M1_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFQ0423061.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            9835..10548
                     /locus_tag="ACG8M1_002394"
     CDS             9835..10548
                     /locus_tag="ACG8M1_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFQ0423062.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
BASE COUNT         3631 a         1801 c         2239 g         2999 t
ORIGIN      
        1 gcacgtagaa gtagataaat ggagtggttt tgcaaatttc ttttatttct agaagttatt
       61 cacgtatacg gatttgtttt tctcacaaat aaaaaggcag gaagtacaat ggatcatttg
      121 tatataaaat atattcatca attttccgtt ttggtgttag gcacactaat tatagcgggg
      181 attgtcgcat ttattattca aggccgtgac atattaacag tacatcaaga gtttttcagt
      241 tatgcatttg gtattcctct gatcgctata aggtctgata acaaaaagtg gaagaaacgc
      301 tattacattc tcttgctatt tttgtgtttt tatctgccac ctaagatttt tactttatta
      361 ggtatacaat gcctatcatt ttcttttatt tcctatatca ttgttttaat tttcctcagt
      421 ttcatagtat ggatgtttta tcttgtcaaa aaataaatga atgtttcatg aacagtactt
      481 catcacagcc taattttttt ctttatgcta tcgttatatt aaagaaatca atcagaaggg
      541 aaagaaagtg atgaaaaaag ttttattagt ggtaaacccc agttcaggcg gtgaacaagc
      601 aaaggaattt gagcaattag cgatagcaaa attggaatcg gtgtttgatg aagtggtcgt
      661 cttgcataca aaaaaagcag gggatgcaaa aaactttact cgcgaagcgg ctacggaagg
      721 gtatcatagt gtgtttgtca tgggcggaga tggaacagtc aacgaaggaa tcagtggaat
      781 cgctgaacaa gaacatcggc caaatttcgg atttttccca ttgggtacgg tgaatgactt
      841 ggctcgagca ttagggatac cgctagaacc tgaggaagcg atcaatcatt tttcgattga
      901 atcagtcaag ccattggata ttggaaaaat aaatgacgac tattttatga atgtcgtcgc
      961 aattggctct atccctgaat caatcaatga tgtagatgcg gagaagaaga cgaaatttgg
     1021 aaaactagct tatttcatgt caggaatcaa acagttagct tccacacaat cctactcgtt
     1081 tcacgtagaa gttgatggaa agaaggaaga aattgagagc agtaccttgc tgataggact
     1141 aactaactca gtcggcggtt ttgaaacatt acttccaaat gcaaaagtgg atgatggtaa
     1201 gctccatttg gtttatttaa aagattcttc tttgatcgat acgcttaaaa cattgccaga
     1261 cctattaaaa ggagtagatg aatctacgaa aaatctagcc taccttactt gtgagcaatt
     1321 agttgtgtca ttagctgatg aggaagaatt gacgacgaat gttgatggag atgaagggga
     1381 taaattacct gtgacaatca aagtattgcc ctcacattta caggtttatt gttaaaatgg
     1441 aggttgtgac cgaggagttg gcgggagaac accgcttgtt cgggataagg gactgtgaca
     1501 agacttttgt cacagccttt tttttgtaca aaaaagaaat ttacacctaa tagaaaaatt
     1561 tttccataaa aatacatatt ttaaatatga aagtacaatt ggaaatagat taaaacgata
     1621 aaataaaatt gtcaaaacgt cagagaggat ggtggagaat gaatcaatgt gtaaaaaagc
     1681 tgattgcgtc gattttgttt gtcttccctc tcttgatggt gacatccgtt tttgccgatg
     1741 tagagaaaac aaacgaatca acgcaatcag agaatcaaag ttttgacaag actacttttt
     1801 cagaagaatc gattacttct gaaactacag aatctcaaag tgaggcttct actaataaaa
     1861 ggcaagaaga aaataagaca agtgagacct cagaagtagc tgaacaaacg tctgatagca
     1921 gtgaagcggc actggcaaga gctgtttcag cggatgggta cagcgaagct gccacaacag
     1981 aagaactggc gcagcttctc gcagacgaat cagtaactaa gatccgactg attcagcctt
     2041 tgactttaga cagggaatta gagatcaaac gagatatcgt tattgatttt ggtggattcg
     2101 ctcacaattt cggcacacac catatttata tcaatgagat acctcagtcg atcgagttcc
     2161 agaattttaa aggaacagct gcacatccag gtggattgac accaaatatc gatggaaatg
     2221 ccattatcat tgcttatatg accgattttt ggggaagcag atatcatttt acgggagaaa
     2281 taaaatttac cgggacactt gatttgtatg atgggtccaa attaggactg atttacgctc
     2341 ctcgtgcaac tgtcacatta gatggtgttt ccggtgtgtt ggatgtccaa ccagtgaagg
     2401 aaggactgaa tgccgctccg ggtaaagcct atttttgtag aagctatcaa ttgaatgtga
     2461 tcaatggtag tcaactttat ggaccgtatc tagggaaatt ctacggtttt ctagattcag
     2521 gagatgagac tggtagtgga aaaacagcgc caggaatcca tatcttaagc ggttcaaagg
     2581 tctctcttga ttatgatcgg gcagatggcg ttagcgatga aggagaggca gtcgatacgc
     2641 tacctggtaa tgtcatgttt gaagtcagtg gttcgggaag cgaattttcg gtaaatacaa
     2701 agatcaatat taccaatgac aacaatcgcg gaatcatcca aatgagaggt tcaggatcga
     2761 aagtcactgt atcgaatggt gggaaaatca ccatcaatac agcaactacg ggcggatttc
     2821 gcttgcaagg agattctagt caaatccatg tatcaagtgg tggacaaatc tcggtcaaaa
     2881 tggctggaga tgacgatcaa cccgggaaca atgggatgcg ttttgtagga aaaggccttt
     2941 ctttgatcgt agaaggagcc ggatcagtta tcgacatcga taagcagagt gggcgttcca
     3001 gcgcagttcg ttttgagaat ggtacgcaaa agctgacagt aaccaatgga ggctcattga
     3061 gggtaagaaa tacaggtgat ggcaaatctt acgtgaacag actcaatcaa ggaaatcaag
     3121 cgatccaatt ttatgacgct tctggttttc tagaaagtcc aggttcagct gattttacag
     3181 tcactggaga aaaatcaaat atcgatatac gcgcagattc cggagcaact gtagatacaa
     3241 ctggagatat tgatttaaat tttacggcag gtgaaaaaac ttatttagtc atggtcggga
     3301 aaacagggga agataagacc ggcatcatca gtggggatgt gttgaatgtg gacttagaat
     3361 ctcctaccta ttttgatttc caaaacaaac ggattggaag cgagaccaat ggcataggcg
     3421 gctgggtatt ccaaggaaat ggagattctt ctttaaagat cgcccattca gaaatcgctt
     3481 tatggcgaaa aacaggcgca acattcgata actttgaaaa agacccggat tatttttctg
     3541 atatgacaga cttatcgatc aatgggaccg acttaggcaa tttcgtatca agccctagtg
     3601 caggtttaac aaatgaattt gctcagacag gtgccggaat gaaaaattat aatcgaatca
     3661 gtgccaataa tcagctcccg atgattgaat ccttaagagt gccaacgaat gcagataaaa
     3721 aaatctatgg gcatgtcgtt gttcccgaag gtgtcgaggc aaagccaaga gatgcttgga
     3781 caggcgaagt agaagtgact ttacgtatta cttacgcaga tacgacgaaa tcatctgtag
     3841 aaattactgc tctcacgcaa ggacaaacag atgaaaatga aggggcagga tataacccat
     3901 ggggagaagg cgaacaaggc ggcttgttcg aagttcaagt acccaatgat gagagattaa
     3961 aaacggagga tcaagtgcaa gttgttgctg ctaaaaaagt aagaggtggc caagaagtga
     4021 cagaactgga ctctgccaaa acgacagtcg atgtgattcc tcctgaacct gctaatttaa
     4081 gtaccacatt gatcaatgca gcttctcgca cgatcacagg tacaggtgaa gcaggagcct
     4141 tggtttcatt gaaaaaaaat caagctgttt tgtcagaaac aactattgat gatacagggg
     4201 aatttgttct ttctatccca gaaaatcaac tttttgcagg agatgtatta gaaattgtat
     4261 taaacgacca agcaggagaa gctactgcta agggtgtgca gaacaagcca agtaccaacg
     4321 atgaaattgg gaatcacaat ccaagtgata cgccagttgt ttatcatgat gccccgcctt
     4381 ttgcacctgc tacgaagatc gtagtagaag gtggtctctc atttcttgcc ccttccaaac
     4441 tcgattttgg tcagatcaaa gcaactggtt tgacacaaga agcatttggc caaatggata
     4501 tacaggaaaa attatggatt tatgatcagc gagaaacgaa aaatccgtgg atcttaacga
     4561 taaaattatc tcagcctttc acaaatgatg caggattttc tatgcaggat gtcctatatt
     4621 tcaagaaagg agaggagtat caattagtga atgaagaaga actggaaatt gtcagaggac
     4681 aaaattcaac gaatgtgcaa gcagattatt cagaatattt aaataacggt cgggcgttta
     4741 aacttgtctt aaccaaagaa aatcagatag ctggtaatta ctcagcagag ataacatgga
     4801 cattagcaga tgcgccgaca gaataaagat caaggaggat gattgatgaa tcgaatatgg
     4861 aataaaagtc atcgaaacaa ctgctcttta cttatgatcc ttctccttgg attcatcctt
     4921 tggcagacac ctgtccatgc ctccgaattc aattttgcgg tagattttga attaccggct
     4981 aatcagattg ataagaacaa aacatatata aatgtaagga tggagcctgg gaaaacacag
     5041 gaaatcccct acacggtctt taaccgaaca gataaatcag taacagttga gacattgatc
     5101 cactccgcta cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa aagtaaattt
     5161 gatgaaacat taagttatga tatgaaaaac ttagcaaaaa cagtgggaga aataactgtt
     5221 cctcctcaaa gtgcggtcac tgagacactt tcactgaaag cgccagaaaa agagctggct
     5281 ggtgtggtcg caggagggat cacgtttcaa gaaaaaaaag agaacgtttc taacaaaagt
     5341 acagttggtg tcgtcaatca gttttctcaa gtgaaagcaa tcttgatttg aaatagcgaa
     5401 aaagagtctt ccccagattt gaaattaaaa aaagcttatg cggatcaaag cgatggaaga
     5461 aatgtgatta aggcgaatct tcaaaatcca aatgcttctt atatgttcgg cttgactaca
     5521 tcggttgaaa tctacaaaaa agaaacaaaa gagccttacc tttcaataaa aaaagaaaaa
     5581 atagatgtag cacccaatac aaattttgat ttacttgtcc cattagaagg aaaaaaatta
     5641 gctccgggac attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg ctggaatctc
     5701 cataccgatt ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa ggatattgat
     5761 ttaaaaaatc agccagaaac atttgactgg cgatggctga tacttgttgg agtcattctt
     5821 attggcttat ttgctggatt atttatttta aaagaaagaa ggaaaaagaa atgaaaaaaa
     5881 caattgcatt aagtaccgtt ctagctggaa gtctattatt atgtacacaa agtgtttttg
     5941 ctgagaataa gagctcagcc actacagaag gaacgatttc tgtgaccaaa ccagatgctg
     6001 caaatcctga agacgttgtt ccagttcctc ctgttgatcc aaatgatcct gatactcctt
     6061 ttacacctga cgaaccaaat cagggaacat ccggattact gacgattgac caagctccag
     6121 atcttgattt tggaacaatc aagttaggta cagcaaaaac agtatatgct gcattacaaa
     6181 gcggaacgga cagtactgga gcacaaacac aagtacagaa tttcgtacaa gtaacggata
     6241 aaagcggaaa ttatgccggt tggaaattat cagtcaaacg aacagaattt attggtacaa
     6301 catctgatac gaataaacta actggttcaa aggtgaaatt caaaaacgcc gtgattcgaa
     6361 atagcgcaac taatagcagt ggaatgccat ctaccgtttc tggaactggc gctgaaggaa
     6421 tcgaaatccc agcagatcag gcagtagatc tagtaactgc aggagcaaat gaagggattg
     6481 gcacatggat ttattcatta ggagagaatg tggaacaagg gagacaatca gtggaattat
     6541 ttgttcctgt atccaattat gctgtagaca actacgtttc aacattcaca tggtcgttaa
     6601 cagatgctcc tacagaagag gaagcgtaaa atcatatcaa cgatttcagg gagtggagcc
     6661 gattcaaggc ccactccctg aaatctgcta tgcttacgtc tcagctctta ttcatcaact
     6721 cgaagcagtt ttttggaagt catggaaacg ttcctttgtc ttttcaaaga tctttcgacc
     6781 aacgagtaag gagtcaccgt tgaaaaattc taacacataa tgagcagaat caattttctg
     6841 caattgcgat aagttgatac agtaagattt taaaagtaaa aagtaagcat acttttctaa
     6901 ctctgtcttc aattgtttta aagaagtatt cactaattta tcttctgtag ttgttttgac
     6961 cataacttgg tttttcaaac ctttgatact ttcaatatat aaaatttccc gaggatacag
     7021 gacgagactt ccaccttttt gatcaataaa gattttatcg acatttacga tctgctgttc
     7081 tttccaattg atctgttcta gcacttgacg aatttgttca gataaattcc tgtcttttct
     7141 gatatatcca atcggaagga ttttccgatt gatgatctct actgcaaaat tcgtataagc
     7201 ggtgaaaaaa acaatattac tatgtgcatt ttttttacgt atttgttcgg cgacatcaat
     7261 acctgtgagt gattgcttca agtcgatatc gataaagaaa acatcgtgat tatcaatagt
     7321 gcccaactgg atcaactgat tgatttgaga gatagaagtg agctgcacga tattctcgat
     7381 atgatgattg accaattctc tgatgatcca ttcgctgtga aactggttat cttctatgat
     7441 aaaatacttt ttcatatgca ggctcctatt aaaaaaatat gtgtacattt tgaaacaaaa
     7501 caatggagga ataagatggt cgcaacagtg acactttatt tgacctttac tttgatttta
     7561 gatttaggta tctatttatt cttttcgaaa caactgctag taaaaaacag ctttggttgt
     7621 atagctttga tggtggtgac acttttactt cctatcccta aagtgagctt tccttaccta
     7681 gttggcttat tattgatgtt tcttttttat tttactacga aaaacctgtt tatcagctgt
     7741 ttgatcagta atcttttttt tgctatcact ggactcagct tttttctggt ttttgatctg
     7801 atggattatt taggaaagag acatcttgga acagcaagtt tttttgcact acttatcgca
     7861 tttattttct atctattagt aaaaagtata gacaaacaga cgagatttct caacttgctt
     7921 tttacttatc caactgaaca ctattttgga ggtatttgta ttttattaag ctggggcgtg
     7981 atttacttgg tattgggaag tgttcacttc cgctcatcta attatctgct tctatctctt
     8041 ttgtcgatag tcatcagttt tttttctttg tttttttcca ttatgttgat cagtttccaa
     8101 gtaaaagaaa gacaacatca ggaatcgctt caactgtatc aaataaatga agaatattac
     8161 catcatctag aggaattcaa acatgattat aaaagtctac tgttttcatt aaaaattact
     8221 cttcaggaaa ataaaaaaga aacgttggaa tttttagaaa tattagaaga tcattctgca
     8281 gctatttttg aaaaaccgca aatacaacag ctaacaaata ttgtatcccc agctgtcagg
     8341 ggtgtctttt taaaatttct agaaaaagca gaatcggaga aaatcccgat ccaagtagtt
     8401 attcctgtcg aagtgaaaac aatcccgatt gatctggttg tttttattcg ctgtttatct
     8461 atttttattt ctaacgcatt cgatcatcgt gtagccgatc agagtccgat tacgatcaat
     8521 ctgctggaag aaaaagaggg atcacgtttt agtatagcga acaaggcaaa tccaacgaat
     8581 ttgacgctat cggagatggt caaaagagga aaaacctcta aaaaaaatgg cgggttaggt
     8641 ctatacagtg cgaaaaaaat gttggatgtt tacgaaaatg cagaactaaa aatcgaattt
     8701 tcaaaacaga atcactattt ttttgtagaa atgtatctgg catctagaaa gagcaaatca
     8761 gcctactgac ttactgtcaa aggataagtt tgaggaaagt ctacacggag atagagacaa
     8821 caacacagca tattcaaaag aaacagaagc gtgatgaccg ttgtcaccct tctgtttctt
     8881 ttgctatgta gttaaacaaa gtagttgaca cttccgctac ttagtattag tacgaaagta
     8941 tacttcatga tactaagtag ataagaagtg aaaagcggaa cccacgatcg tcaaaatgct
     9001 aactgctttg cttacaccag ataaagggaa gagcaatatc gcttatttta ggcgtggaga
     9061 agcaagcaaa tccctacgat cacaaaaaaa atgctgaccc agcagttaag agagttagaa
     9121 caagatgaaa gtatccatcg aaaagcctat aaccaagtcc cgcctaaagt agagtactcg
     9181 ctcaccgaag aaggaaaatc attaagagag attctagtag cgttgtctgt ttgggaagaa
     9241 gaacgtatcg aaaaacaaaa agcctcaagg gaagaagaca cgctactgca tacacatggt
     9301 ggctacctaa attattgatt ttctatgaca tttattttaa ataaaagaaa acaggagttt
     9361 ttttaaaagc atcatctatt ttttatgtaa aaaaatggta tgattaatca agtaagaagt
     9421 gattggaaga aggcaagcaa atgaatagta tggaaaaagt caaccagttt agagatgaac
     9481 gtaattggcg acaatttcat aacgaaaaag atttggctat ctctatttct ttggaagcat
     9541 ctgaattgtt agaacttttt caatggaaaa cgccggaaga agtaaaagaa acacaattag
     9601 aacgaatcaa agaagaactg gcagatgtat tgatctattc atacatgatg gcagacaacc
     9661 ttcacctgga tctagatgag atcattgaag aaaaattgat caaaaataat ttgaaatatc
     9721 ctgtagaaaa aagcgcaggt gtacgaaaaa aatacacaga gttgtagaaa tgtgtcattc
     9781 ggctgttgga aagagcaaaa gaaaaacagt aaaatgagtc tggagggaga gaaaatgaaa
     9841 aaaaaaggaa aagcaaaaag atggctagtc aatatcctct tgttcctctt gttattagta
     9901 ggactagctt tgattttcaa tgaacagatc aaggattatt ttgtcagaga gacaggagat
     9961 aaatatgcta tagcgaatgt aacaaaagaa gatctgaaaa agaataacga taaagatgtc
    10021 agttttgact ttgatgcggt agaaccaatg acgacagaag gggtcatgag gtcgcaaatg
    10081 agaggaacag atctaccagt gattgctagt atcgcagtcc cttcagtttc aatcaattta
    10141 ccggttttca aaggcttgga taatacgtca ctactttacg gagcaggaac attatctcca
    10201 gatcaagaaa tgggaaaagg aaattatgcc ttagcaagcc atcgtgcaac gaaccctgaa
    10261 ttgctgttta caccgctaga aaatttagag atgggtgcca agatctattt gacagattta
    10321 gaaaatgtgt atacatacaa aacatttttt aaagaaaaag ttgctcctac agatacccaa
    10381 ttactgaatg aagtcgaggg aaaagaaatt gtcacactaa ttacttgtgg cgacatggac
    10441 gccgtcacgc gactagttgt acaaggagaa ctggaaagtg ttacatcgat aaaagatgcg
    10501 acagatgata tgagatctgc tttcaatcta gagacaaaaa cattttagga tactgggaca
    10561 taagtcgtta cagattaaaa acagccaaag gatatgaatc gataaggaaa aaccaatttg
    10621 ctgaaaaaaa gagaaacgca aagaggtgca tctctgattt ggttgttttc
//
LOCUS       DAZKNV010000075        10641 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000075 DAZKNV010000000
VERSION     DAZKNV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.076"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..525
                     /locus_tag="ACG8M1_002395"
     CDS             <1..525
                     /locus_tag="ACG8M1_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423063.1"
                     /translation="LEKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTI
                     SNEINQYREREPEIQPAEVKQEHKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRT
                     LHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKN
                     EIYYEQQLSQKERV"
     gene            586..2055
                     /locus_tag="ACG8M1_002396"
     CDS             586..2055
                     /locus_tag="ACG8M1_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFQ0423064.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2066..4175
                     /gene="topB"
                     /locus_tag="ACG8M1_002397"
                     /pseudo
     CDS             2066..4175
                     /gene="topB"
                     /locus_tag="ACG8M1_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            4191..4340
                     /locus_tag="ACG8M1_002398"
     CDS             4191..4340
                     /locus_tag="ACG8M1_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423065.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4421..5017
                     /locus_tag="ACG8M1_002399"
     CDS             4421..5017
                     /locus_tag="ACG8M1_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFQ0423066.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            5030..5929
                     /locus_tag="ACG8M1_002400"
     CDS             5030..5929
                     /locus_tag="ACG8M1_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFQ0423067.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKEQKLAYQRHQQMNREMER"
     gene            5932..6416
                     /gene="ssb"
                     /locus_tag="ACG8M1_002401"
                     /pseudo
     CDS             5932..6416
                     /gene="ssb"
                     /locus_tag="ACG8M1_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            6438..6695
                     /locus_tag="ACG8M1_002402"
     CDS             6438..6695
                     /locus_tag="ACG8M1_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423068.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(6854..6988)
                     /locus_tag="ACG8M1_002403"
     CDS             complement(6854..6988)
                     /locus_tag="ACG8M1_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFQ0423069.1"
                     /translation="MLKSIKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK
                     "
     gene            7131..7391
                     /locus_tag="ACG8M1_002404"
     CDS             7131..7391
                     /locus_tag="ACG8M1_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423070.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            7840..8046
                     /locus_tag="ACG8M1_002405"
     CDS             7840..8046
                     /locus_tag="ACG8M1_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFQ0423071.1"
                     /translation="MRKKFDYLGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIEEKGKKR"
     gene            8046..8297
                     /locus_tag="ACG8M1_002406"
     CDS             8046..8297
                     /locus_tag="ACG8M1_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423072.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGCELHYQENLETYENEYWLTKLEN"
     gene            8313..8750
                     /locus_tag="ACG8M1_002407"
     CDS             8313..8750
                     /locus_tag="ACG8M1_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423073.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCFEIGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            complement(8861..9088)
                     /locus_tag="ACG8M1_002408"
     CDS             complement(8861..9088)
                     /locus_tag="ACG8M1_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423074.1"
                     /translation="MKQNTSITKNTARFNCTAALSRISISPTNSTNNKGIIFFKWITF
                     FLLSYRALPVYFAPPKRRGRLVRNKNHSLSY"
     gene            9186..9374
                     /locus_tag="ACG8M1_002409"
     CDS             9186..9374
                     /locus_tag="ACG8M1_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423075.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IACIGQYLYCIRGRKLYA"
     gene            9492..9698
                     /locus_tag="ACG8M1_002410"
     CDS             9492..9698
                     /locus_tag="ACG8M1_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423076.1"
                     /translation="MKYNLLDHKRMWVEKLEEDLEQLELLGHNKTSTVYKEGLKRTKK
                     AQKELATLESRVQKKEVDLTHTYL"
     gene            9708..9941
                     /locus_tag="ACG8M1_002411"
     CDS             9708..9941
                     /locus_tag="ACG8M1_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HFQ0423077.1"
                     /translation="MADKRKEKIQKLLALAADVNDEESVSALAKAQQLMMDYDLTEDE
                     IFNYHEQQRIEAVETHVIYRGRPQKWLYRLFRN"
     gene            10284..10466
                     /locus_tag="ACG8M1_002412"
     CDS             10284..10466
                     /locus_tag="ACG8M1_002412"
                     /inference="COORDINATES: protein motif:HMM:NF013850.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HFQ0423078.1"
                     /translation="MSVSTLGITVDAATYYGNGVYCNTQKCWVDWSRARSEIVDRGVK
                     AYVNGFTKVLGGVGGR"
     gene            10456..>10641
                     /locus_tag="ACG8M1_002413"
     CDS             10456..>10641
                     /locus_tag="ACG8M1_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423079.1"
                     /translation="MEDKKEKLFDLIANAYNSKSYNNVEVKEGFLQDAKKIREDKPYP
                     EIIISVYKHLSKLKAEER"
BASE COUNT         3880 a         1739 c         2233 g         2789 t
ORIGIN      
        1 ttggagaaag ctattcctta tattgcagca tggacgaaga atggtcagac gttggatgat
       61 aaggaagctg cggaacgtgg gaaaatcatg aatgatgtca gccgtgtcgc aaatgaattc
      121 attcaaacca tttctaatga aatcaatcaa tacagagaaa gagaaccaga gatccaacca
      181 gcagaagtga agcaggagca taaaaatact gtagaaacgg cagaacaaaa gaatattgtt
      241 cctgttggtt cactttggat cgacaagaaa gacgggaaag taatggaaga agatacgggt
      301 cgaacgttac atttgaagga tgcggcgttt attgaagatc cacagcataa tcaagtaatt
      361 ttaaaaggaa aaagttatgg aaaagagatc caaacggcgt taccttcaga agaatttgcg
      421 ctaggaaatt cattccgatt ttcacttgag acagtgtcag aagtggcaaa acgaaaaaat
      481 gaaatctatt atgaacaaca attgtcacaa aaagaacgtg tataaaacaa gtaaaaaaga
      541 ctatctgaaa aacggatagt cttttttctt ttgggaggtt ttaaaatgac cgagaaaaaa
      601 atgagtctta ttgatcgatg taaacagatc gatatagtgg attttgctcg aaacaatgga
      661 atggctgtag tcaataaagg acgagactat cgcttagaag accatgattc atttgttttt
      721 gatcgaagaa aacaacgttt ttattggaac agtcaaaata ttagtggcga cattattgaa
      781 ttagctaaac tttttttcat agacaaagag atccaagacc ctaagcaaca atttaaagca
      841 gccactgatt ttattctaaa gaatgaagac aaaacagaac gagtggaaaa tcttcatttt
      901 gagacagaaa agtacaaaga tcaccccgtt gattatcaac cactcacaga aaaaggaagg
      961 aattatctga aggaagaacg aaaactacca gagtggctga ttgattatgc agaaaaagaa
     1021 gggttgattg ctgaactaaa gccgaaacat gaacggcaaa attttttagt tggagacgac
     1081 cgtttagatc atgcggttgc ttttttatgg aaagatccac agacaggaga gacagtaggg
     1141 gcaagttatc aaggaacgat cgtcgatttt aatcgtttcg gtaaacgggg aacgtataaa
     1201 cacattgaca agaatcctac gccaaatcac ggatttaatt taaaaatagg cgatccgaag
     1261 catttaaaat tctttgaaag tagtattgat ctgttaagtt acgctgcatt gaatcgggag
     1321 aaactacaag atgcctggtt agtttcgatg gacgggttaa aacatcatgt aatcagtcat
     1381 tacgttgaag agtcgatttc tgaattaaga cgaaaacaaa catttcctca atcgattgaa
     1441 atatgtgtgg acaatgatcg tgcaggacat attttttatg aaaaagaaca gatgaaggga
     1501 atcgttgatc cttttaccaa taagaaaatc cgttgtgagc gaggaattcc aaatgattgg
     1561 caagtaccta aagaatacaa agctacttat gaagcagtcg caaaagaaat gagtgttgaa
     1621 cctgaagcaa ttatggccat acacaaaact gaaactaatt tacagctgac aaatcaattg
     1681 gtgtctgctc atgatgttca atctacgttt ggaaagatgt tggcgaaggg cgaaccagta
     1741 gaaacaattg atttgaaaga agcatgtacc acggtcgcga aggaactgaa agtatgtgaa
     1801 cgcgcagatg gaacatacaa ctttgatcgt ttttatagta gaaaagccaa cataaaagac
     1861 gttaatgcag gaatccttct ttcctataaa gcagaacaat actacaaagg ctataaaaag
     1921 catgaacatg aatttgtacc tgaagtgaaa aaggattgga atgatcaatt gaagcatgag
     1981 atccagcaac aagaaatcag aaagcaaaaa cgtgcgatgt tgtttcaaca aggcagacaa
     2041 caagaaaggg agtgaagtcg tcactatgaa aaccgtcatt ttagcagaaa aaccgtcaca
     2101 agcgaaggct tatgccgata gcttttctaa agctacccga aaagatgggt attttgagat
     2161 ccaagatcga ttgtttacag gagaaactgt gatcacgtat ggttttggtc atttagtcga
     2221 gttagattcg cccgatatgt acgatgaaaa atggaaacaa tgggcattag aacatttgcc
     2281 tattttcccc aatcaatacc actatcatgt tcctaaagat aagaaaaagc agtttagtgt
     2341 cgtcaaacga cagctgcagt cagctgatac gattgtgatc gcgactgata gcgatcgtga
     2401 aggggagctg attgcctggt caatcattca acaagcaggc gccaatcaag gaaaaacctt
     2461 taaaagactt tggatcaact ccttagaaaa agaagccatt tatcagggat tccaacagtt
     2521 acgagacgca gaagagacct atccaaaatt tgaagaagta caagcacgtc agatcgccga
     2581 ttggttaatt gggatgaacg gtagcccact gtatagttta ctcttgcagc aaaaaggcat
     2641 accaggaagt ttttctttag gtagagtcca aaccccaaca ctctatatga tttatcaatt
     2701 gcaggaaaag attagaaact tccaaaaaga accatatttt gaaggaaaag cccaagtaat
     2761 cgctcaaaat ggcgcatttg atgcgaagct tgatccaaat gaaacccaag cgacacaaga
     2821 agcatttgaa gcctatttaa aagaaaaagg tgttcaatta ggaaaacagc caggtacgat
     2881 ccttcaagtc gaaacagaga aaaaaagtgc ggctagccca cgtctttttt ctttatcgag
     2941 ccttcagtct aaaatgaatc aactcatgaa agctagtgcc aaagatactt tggaagccat
     3001 gcaagggttg tatgaaggaa aatatctaag ctatccgcga acggataccc cttatattac
     3061 ggaaggggaa tatgcgtatc tgttggatca cttagacgaa tacaagcatt ttttaaaagc
     3121 cgaagcgatt ccgactccta ttcatacacc gaatagtcgg tatgtgaata ataagaaagt
     3181 ccaggaacat tacgcgatca ttcctacaaa aacggttatg acagcagcgg cttttgaaca
     3241 actaagtcca ctgcagcagg ctatttatga acaagtgtta aaaacaacgg tggccatgtt
     3301 tgcggaaaag tatacctatg aagaaacaac gatcttgacg caagttcagc agcttcagtt
     3361 aaaggcaatc gaaaaggtgc cgctagatct aggttggaag aagttatttg gaaaagagag
     3421 cgacggaaaa gagaaggaag aagagccgct acttcctaaa gtgacaaaag gagaaatggt
     3481 gacggtggat ctacaagttc ttgaaaaaga aaccaagcca ccacaacctt ataccgaagg
     3541 tacgttgatc actgcaatga aaacagctgg gaaaaccgtg gatagtgaag aagcgcaatc
     3601 catattgaaa gaagtggaag gaatcggtac agaagcgaca cgggcgaata ttattgaaac
     3661 cttgaaacaa aaggaatata tcaaggtaga gaaaaataag ctcgtggtga cgaataaagg
     3721 gattttgctt tgccaagccg tggaaaaaga gccgctgctt acgagcgccg aaatgaccgc
     3781 caaatgggaa agctacttgt taaagatcgg tgaacgaaaa ggaacacaaa ccacttttct
     3841 agccaatatc caaaaatttg tctctcactt attggaagtc gtaccagggc aaatccaatc
     3901 cactgatttt ggatcgacgt tacaagaagt gaaagcagcc agtgaaaagc aagaagccgc
     3961 gcgtcattta ggaatttgtc caaaatgcca ggaacaagaa gtcttactct atcaaaaggt
     4021 ggcagcttgt acgtctgaag cctgtgattt taaaaggtca gaagggttca tttgaagcaa
     4081 cgattgtttt aaaagaagac ttcactacag gctttgaatt ttctgaaaag aaaaaaacga
     4141 acttcaagaa aagaacacgc cgcactgcaa aataatggag ggttaatctt atgcgtaata
     4201 ccacacacaa acaacaagaa atcgaaaatc aaaaagccaa aattcgttca gaacaggaaa
     4261 aaatgcgtgc cagcaaacga agactgcagc aattgaagaa ccagcagagg attcaaaaag
     4321 aaatcgaatt agatcgataa aatcttccta actattgtat acgtataaac ttatgttata
     4381 ctgtttttat aagtttatac gtatacaaag gagggagaaa atgacaaaag caatggtata
     4441 caagctgcta gaagaattta atggaacttt ggctttgaag gatgccaaaa aagcgggcat
     4501 ttctcctgta acgatcaaac gtatggtaga tcgaggggag ctggatcgag agtatccagg
     4561 ttttttcacc ttacctggtc aatttcctga tgaattgttt atggcgcaaa aaaaatatga
     4621 acgcggcatt atttcacata ttaccgcgtt agatttgtat gatttaacag atatgatccc
     4681 tagacagatc gatctgactg taccttacgg ttatcacgtt tctgaaaaag gattgaagga
     4741 attcgcagtt gagctacact atacaaaagc ggaatggtat gaattaggta agattgaaat
     4801 aaaaagtcgc tatgggaatc ctattatagc ttatgatcca gaaagaactt tatgtgacat
     4861 ttggaatccc tggtataccg ttgaggatga aatcaaagta aaagcaatca aaaactatat
     4921 ggagtcggac agaaaaaatc ttagaaaatt gaatgagtat cgacgaattt taccaacaga
     4981 caaaacgatg cgttcttata ttatggcttt aaattaaagg agaagataca tgacacctac
     5041 gcagttaaaa gcaaaagtga agaatatttc tagagaaaaa gaagttgatc cgcagcttgt
     5101 tttaagacat tttatgatgg aaaaattctt ggaaaaaatc tcagagtctc cttatcgtga
     5161 aaattttgtg ttaaaaggcg gcttcttgat tggctcaaag tatggcattg aaaatcgcac
     5221 aaccaaagat attgatacga ctttacggga aatgaaagta accaaagaaa cattaacaac
     5281 ggttctaaac gaaatttttt caacgccgac gaaagaaggc attcaatttg agattcaagg
     5341 aatgaaagaa acgagagaag ccgattacta tccaggattt agcttacgtg tgctggcaca
     5401 tttggaaaac atgcggccag attttaaggt agatgtgact acaggtgact cgatctatcc
     5461 tgcaacgatc actcacagtc ataaattgat gtttgaggat cgaacgattc ctttggaatc
     5521 ctatcctaca gaacaaatta ttgctgaaaa attaagtgca acctttgatt ttttaacaga
     5581 taattcgaga ggaaaagatt tttatgatct ctatactatt cctaaaatgg agaagatcga
     5641 tgagaagacc ttgaaagata gtgtgagaaa tacatttaca cgtcgaggaa aaactgatcc
     5701 gttaaagata tactatgaaa aggatatgga tgtactgaaa aatagtcacg agctaaaaga
     5761 tacctggaag aaatatcaaa aaagcaatcc ttatgctgca tcgatcacgt acgatgagac
     5821 aatggattcg attagtaatt tgatggaaaa agtgattcac gtcgaagaaa aagagcaaaa
     5881 actagcttat caaagacacc aacagatgaa tagagaaatg gagagataaa gatgattaat
     5941 aatgtgacat tagtaggacg cttaaccaaa gatcctgatt tacgttatac cgcaagtggt
     6001 actgcagtag cgacttttac cctagccgtc aaccgaaatt tcacgaatca aaacggcaat
     6061 cgagaagccg attttattaa ctgcgtgatt tggcgcaaac cagcagaaac aatggcgaca
     6121 ttagctaaaa aaggtagctt gattggtgta gttgggcgga ttcaaacgcg gacttacgac
     6181 aaccagcaag gacaacgtgt atatgtgact gaagttgtag cagataactt tcaactatta
     6241 gaaaataaag cagcgacaga gagccgtgcg cacgctgatc aatcgtccac cagtccaagc
     6301 accgccacct ttgaacaacg gatacagcga cgcctaacaa caatggattg aacgcttcac
     6361 agaatccatt tggtggacaa tcaatcgata ttagcgatga tgatctaccg ttttagtttg
     6421 agaaagaagg agtaagcatg gcaaaaaaaa ttagtctgac gatggatcta ttgatacccg
     6481 taattgcatt tatagacggg atttctttgg gcgtcactga aaatcctttg gtaaatagaa
     6541 ttgcgaaagg atcactattt cttgtattcg tgtatcttgt ctgttcttat cttttaaaaa
     6601 gagcaggaaa ggataattcc ttttggcgat tgactaaagt cacagtagca gcgacagctg
     6661 ttatacttac ggctattcta ccgctttata tgtagagtta acgggaaatc gttgaacttc
     6721 ttgcgaaata ttgctataat gaacatgaaa aagaggagtt gcgctaacaa cccctcatta
     6781 acagcaccga ttaaagaacg gtggcagaat attagttatt tggaaataac cgctgacctg
     6841 ctaaagtaga cggttatttc tttttgtcat ttttaagcat atttacaatc aaactaatca
     6901 aagcaatggt aaacatacca aaaccaagaa tggtttgaat tgtctcatat gcggacaaaa
     6961 ggcttactcc ttttatagat tttagcactt acattcataa gcaccaccac ctttccagaa
     7021 gtcgccaccg tcttcaaact ttactgtctt gactattata gcatatctaa aatcgaataa
     7081 aaattctcaa ttttaactgt ttttgctata attttagcga ggtgatcgtg atgaacaaat
     7141 atgttggttt gcttgataaa atccgagtaa taaaaacaca accattattg gttcgcttta
     7201 ctttacaaac aattcatgaa tcgattaatt gtgtagttgc agatattgaa attatcgata
     7261 aattgttaat tatggatgat ggaaaataca atattgccgt cacaggtcat ttcaataaac
     7321 ggaatcaatt agtcattgaa tcgatgcaaa ttagaaaccc tgatcatttt acgcgatcaa
     7381 tgggcatata aataaaagaa gagctgcaat cctaatgtag gactgcagct ctttttgttt
     7441 tacatagaaa caggaagaaa gggaaaggcc tgtttaggaa ggcacaagtg ccttctcaat
     7501 tgaaaaacct ttctctcact ccaaccgcca ccgccgttcg agaagaaagg aagtgaacgt
     7561 tgcacgttca ctaagataag gggtcttgct ttgtaagaca aaataggaaa agcttcctct
     7621 caccaaaagg ttcgttcctg ttcgctatct ctttattgat ttgccagacc ggcaacaagt
     7681 tgccttttat caccaaaaag cgacaaggac aagggtaaat ggcacgctgc gcgcccttgt
     7741 ccttgtcgct tttcgttgat tcattctggc caacaaatca ataaagaaag aactaacgaa
     7801 aggaagtaaa acctttccta agaggaggca gaatcaatca tgcgaaagaa atttgattat
     7861 ttgggtgttc ccttcagcga attattccca aactatcatg caccacatac tgtcgaatgc
     7921 gattgtggag aaagagcgaa atgtatcaaa agctattgtt tgtatcaatg tccaacatgc
     7981 gggaaaaaat ataccttgtc ttatggcgat tatattttga ttgaggagaa aggaaagaaa
     8041 cgctgatgaa aacacaacac aaattattga ctgtaaaaga agtcgttcaa attttggtgg
     8101 acaaagaagt catttctgaa aaagtagcag aagctttact tattccgcgg tactggacga
     8161 tagaaacccc tttagtagag gatgcaccga ctatgctatt tgaagaccta gtgaagattg
     8221 caggatgtga actgcattat caagaaaact tggaaactta tgaaaacgaa tattggttaa
     8281 ccaaattaga gaactaaaaa ggagaaaaaa atatggctca aaattactat gacgaatttg
     8341 tcaaattacc tttggataaa atggcacaaa aaatggagga tatgacgttc ctatacaacg
     8401 aaacacgtgt tccaaaaaaa cattataaag aaaaattgtc ggtagctgtg gaagaaatga
     8461 ttgaatcagg tgtcgaaatg aatcttattg cgacgtacta tcgaacactg gaagaactga
     8521 aaaagcaaaa tgcaaaatgg tttttccaag ccttactatg ctttgaaata ggtgtcaaac
     8581 caagcactat taaaccttct gaataccagg ctttagaact aacgtatgcg aaatttatcg
     8641 aaacgaaaaa agccaagact gtttcaagtg aatggttaga ttattttgaa aatatcaata
     8701 agtatggcgc atattacacc atgaaaaagg aagacaacga aaatgaataa ggtgatttat
     8761 caactaacaa cggattccat atcaacgatt tgaaagaaaa aaaggtcaat aatcatttat
     8821 accgaaaagt gagaatgtgt ggaataagga caaaaaaagc ctagtaacta agggaatggt
     8881 tcttatttcg caccaaccgc ccccgccgct taggtggtgc gaaataaacg ggcaaagccc
     8941 gataacttaa gagaaagaag gtgatccatt tgaaaaagat tattccctta ttgttagtac
     9001 tgtttgttgg cgaaatactt atgcgagata gtgcagctgt acagttaaac ctcgctgtat
     9061 ttttggtaat actggtgttt tgtttgatct tttggcggtt tgtattagtc ctcgtgagtc
     9121 tactattcaa gatgattgca gccatatttt tcatggggtt atttcgatga aaggagagag
     9181 taccaatgcc aattgcaata ggaaataaac ggttacccgt gacattagat gaaaagagac
     9241 aaaaagaatt gcagcaacta aagcagaagt acggcaaaag tgaatccagg attatgtgta
     9301 ttgcgttaga tttattgatt gcctgtattg gacaatatct ctattgtatt cgaggaagaa
     9361 agctttacgc ttgaatgcga taagttaacc cgatatatcg atccaaaatt ctatgaggat
     9421 aaaaacctgg catgggaact ggctttatag acagagtgct agtgcaagta aaggaagaaa
     9481 ggaagatcac catgaaatac aatttattag accataagcg aatgtgggta gagaaattag
     9541 aggaagactt agaacagttg gaattgttag gtcataataa gacttcaacg gtgtataaag
     9601 aaggactaaa acgaacgaaa aaagcacaaa aagaactagc aacactggaa agtagggttc
     9661 agaaaaaaga agtagactta acacacactt acctttagga gtagaaaatg gcagacaaga
     9721 gaaaagaaaa gattcaaaaa ttactggcgc ttgcggcgga tgtaaatgat gaggaatcag
     9781 tgagcgcatt agccaaagcc cagcaattga tgatggacta tgatcttact gaagatgaga
     9841 ttttcaatta tcatgagcag caacggatag aagcagtaga aacgcacgtg atctatcgtg
     9901 gacgtccgca aaaatggctg tatcgtttat ttagaaatta agataaaaaa ggctagttaa
     9961 caggtttgtt gactggcctt ttttgatatg tttgtacatg ttttattgtg ttttaatttt
    10021 tctctttttt atagcaagct ccttttataa taaatattcc gaaaagtgaa gaccattttt
    10081 tatttattaa gactattatt attagtgaga taaaatttga ttgatcttac agaatattgg
    10141 tgacgattat gacactaaag atactattta tgaaaatttt gcaaaaatgt tctgaaaatt
    10201 acatataatt gttttataaa aaagggaggc aattatatga agaaaaaatt tgttagtatt
    10261 ttttgatttt aggaattgtt ttattgagtg tatctacttt aggaattaca gtagatgctg
    10321 caacttatta tggaaatggt gtttattgta atactcaaaa atgttgggta gattggagta
    10381 gagctcgctc tgagattgtt gatagaggag taaaagctta cgttaatggt tttacaaaag
    10441 tgctaggtgg agtcggtgga agataaaaaa gaaaaacttt ttgacttaat tgcgaatgca
    10501 tataattcaa agtcatataa taatgtagaa gtaaaagaag gatttcttca agatgctaag
    10561 aaaatacgag aggataaacc atatcctgaa attattatat cagtgtacaa acatttatct
    10621 aaattaaaag ctgaggaacg c
//
LOCUS       DAZKNV010000076        10616 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000076 DAZKNV010000000
VERSION     DAZKNV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.077"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            288..2234
                     /locus_tag="ACG8M1_002414"
     CDS             288..2234
                     /locus_tag="ACG8M1_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0423080.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2237..2692
                     /locus_tag="ACG8M1_002415"
     CDS             2237..2692
                     /locus_tag="ACG8M1_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0423081.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2706..4034
                     /locus_tag="ACG8M1_002416"
     CDS             2706..4034
                     /locus_tag="ACG8M1_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFQ0423082.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4068..4352
                     /locus_tag="ACG8M1_002417"
     CDS             4068..4352
                     /locus_tag="ACG8M1_002417"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0423083.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4354..4869
                     /locus_tag="ACG8M1_002418"
     CDS             4354..4869
                     /locus_tag="ACG8M1_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HFQ0423084.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4885..5547
                     /gene="rpe"
                     /locus_tag="ACG8M1_002419"
     CDS             4885..5547
                     /gene="rpe"
                     /locus_tag="ACG8M1_002419"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFQ0423085.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5554..6126
                     /gene="hxlB"
                     /locus_tag="ACG8M1_002420"
     CDS             5554..6126
                     /gene="hxlB"
                     /locus_tag="ACG8M1_002420"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFQ0423086.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6313..7833)
                     /locus_tag="ACG8M1_002421"
     CDS             complement(6313..7833)
                     /locus_tag="ACG8M1_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFQ0423087.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8076..8261)
                     /gene="tnpB"
                     /locus_tag="ACG8M1_002422"
     CDS             complement(8076..8261)
                     /gene="tnpB"
                     /locus_tag="ACG8M1_002422"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFQ0423088.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8245..8427)
                     /locus_tag="ACG8M1_002423"
     CDS             complement(8245..8427)
                     /locus_tag="ACG8M1_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423089.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8668..8886
                     /locus_tag="ACG8M1_002424"
                     /pseudo
     CDS             8668..8886
                     /locus_tag="ACG8M1_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9381..9980
                     /locus_tag="ACG8M1_002425"
     CDS             9381..9980
                     /locus_tag="ACG8M1_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0423090.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10044..>10616
                     /locus_tag="ACG8M1_002426"
     CDS             10044..>10616
                     /locus_tag="ACG8M1_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiH family protein"
                     /protein_id="HFQ0423091.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         3508 a         1670 c         1984 g         3454 t
ORIGIN      
        1 tataataaaa aaatacgaat tttagtgacg ccattatatt gtttttattt ttcaattgta
       61 atatttcata ttacttccat aataaggagt attttctatt ggaatatctt agctctttta
      121 aggatttctc cttttttgtt tctcattttt taagattatt tggatttcct ttacaacaaa
      181 cttccacaag tattattgac atagatgtaa ttgagggaag ggggttccag tgctagaata
      241 aataatgaaa agaggtaaca aatgctagcg ttaagaggtg aacaagtttg attgaaagac
      301 atgtaaattt attaaaatta ttaagtcgac aagaagactt taaacccgct tcttttttta
      361 gtgataaatt ggcagtgtcg accaagacca tttatcaaga tattgaattg ttggaagatt
      421 atgtagttaa ttaccaagta acaattgagc gattaccttc tttgggtatc aaactcatag
      481 gtgataggaa aaacgttgaa catttgattt catcggtaga gaattatctt gaaaaagata
      541 tttattctcc agaaaaaaga cgtgtcgaga tcattaaaga agttttgttt ggtgataagc
      601 ctgtttcttt aactcatttg tctcaaagtt ttatggttag taaaacatcg ttatacaatg
      661 acctgagaat tatcaataaa attattggca gtggagaagt taagttgcag tcatctgcag
      721 aaggaattag ttttactggt aatgaacaag caattcaacg agcaatcaag caacttgtat
      781 tctattatgc gaatgacatg gaatcaaaaa cattttttca agttttaaat atgttgtttg
      841 attcaaaagt tattagtgtc attcatgatt tgctattcaa tgattacagt gaactgactg
      901 aaaaggtttc tgattactat gttcggtcat tgatttctac tttagttatc caatgtaacc
      961 gtttactgaa aggtcatcat ttaactgttg aagaagaatt cctcttcaat agcattcgct
     1021 atatggaaac gtacattgtg gcaaatggtt taattgaaga attgaaggca aaattgaatc
     1081 ttccatttta tgacgcagat aaagaatatc tatgtcgtca actatttgca catcgtgtga
     1141 caaataattt aaaaaccagc aatgaagagt acgctatgag cgttcataaa ttgattgaaa
     1201 gaatgagtga gattgaaaaa attgatttga ctcaaaatga tcgattatat caatccttat
     1261 tgtatcatgt gccagcaatg gtccttcgtt taaaaaaagg tattaaaatt caaaatccgt
     1321 tattagaaaa tatcaaatct caatattcag aactctttag catagtatgg tacgccatgt
     1381 ccatccttga agaagaattt gatgtgactt taacggacga tgaagtttcc ttaattttga
     1441 ttcattttca gattgctatt gaagatcagt ccaaagcaaa taatatcatc attatttgcc
     1501 aatacggtat ttcttctgcg caattaattt acaataaagt tcgacggttt ttaccagcaa
     1561 aagataatgt agaaatatca actttagata agtttcattt agctgaaatt ggggaagttg
     1621 atttgattat ttcctctctt tcctttgatg caggtggtat acccttagta agggtatctc
     1681 cattggtaag taaaacagat tatatgaata ttatggaagc ttatactaaa tatttaatag
     1741 aagaaccttc gcgatttatt caaaatgaac tgattcctaa agcggttaaa gttcccacca
     1801 tatctaaatt tgttcaatca tctttagtaa aaacaggagt acaggtggaa agcaaagaag
     1861 aatgtttgga tttgatgatt tccgaactag aagccaattc attagttact gaagagtttc
     1921 gtgcttctat cttctctaga gagaaaatgg ggaatactaa tttagaaagt ggtgttgctt
     1981 taccgcatgc gaatccatca atggtcattg aatccaacat ttttattgta gcattaaaaa
     2041 atgcgattaa ttggggcgat cgaaaagtca aattagtcat tatggttagt ttagctgaag
     2101 aagatgtatc tgagattaga ggagtatatg aagaacttta ccaatttatt gggcaaaaag
     2161 aaatggtcga tcgcttgtta caagttcatg atagcgaaaa attactaaga atttttcaac
     2221 aaaaaggaga ataaaaatgt atctagataa agaattatgt ttatttcaat tagaagtgaa
     2281 agatcaaaaa gaattgtttc aagtaatgtc tgaacaatta aaaaacgctg gttgcgtgaa
     2341 agatagtttc ttagaaggta tcaccaaccg tgaacaagaa tttccaactg gattagaagt
     2401 aaatcaaatt gggtttgcta tcccacatac agattccgca catgtaaata gctctcaaat
     2461 ctgttttgcc tcattaaagg aaccactggt attttcagat atgacagata aatctcatga
     2521 aatacctgta cgtttagtct ttatgttggc aatgtcacaa cctcatgaac aaattgatac
     2581 actacaaaac ttagttagcc tatttcaaaa tgaagaaaaa gtaaatgaat tacttgcatg
     2641 taccacgaaa gaagcattta ttgagttagt acattctgca ggagtttatt aggaggaata
     2701 gagagatgga tattgtatta aatgcctttg aatggtttat tggattaggg tcaaacgtct
     2761 ttttaccact gattattttt gtaatcggga tattatttgg attaaaacct ggtaaagcat
     2821 ttgtttccgg cgttactgtt ggtatcggtt ctattggttt aggattagtt ttaagtttat
     2881 tatcagatgg tttaggaaca gcaattcaac aaatggggga acaatacggt ggtggcctga
     2941 atatcctaga tattggcgta ggtgttggtg gacctttggc ttactctaca tcattgggaa
     3001 ttttaatgat tccaatttca ttaattctta acttcatatt tgtggttttg ggttggacaa
     3061 aaacattgaa tgttgatatt tggaactttt ggttcgcaat tttcctaggt atgattactc
     3121 aatctgttac gggaaacttt tggtttggct taattggcgc gattgtcgca gtaattttac
     3181 aatggttctt agcagatcgt acacaaaaaa ctgttagcga atttttcggc tatccaggaa
     3241 tctctatcac acatatgatg ggattatcag gagtactatt tgccaaacca gtaaattggg
     3301 tttttgatcg tattcctgga tttaataaaa tagatgcaga tgcagaaaca ttaacaaaac
     3361 gtttcggtgt tttaggtgac acagttgtta ttggcctaat tatcggtatt gtagtgggta
     3421 ttatggcagg ctatgacgta gcaggaattg gaaacttagg aattatgact gcggcagtga
     3481 tgaagattat gcctaaaatg gtagcaatgt ttatggaagg tttaatgcca attgcagaag
     3541 cggcgaaaga atttacgaat aaaaagttaa atggtcgcca agtaaacatt ggaatggatg
     3601 cagcgttaac tgtgggtcat ccaactatta tgtcaacttc tctattgctt gtaccaatct
     3661 cattattgct agcactaatt cttccaggaa ataaagtatt accttttgga gatttagcat
     3721 tctttgcttt cgccatctgt ttaatgattc cttattttaa aggaaatatt gtgagatcat
     3781 tagtaggatg ttcgttgtat gttgttacaa cattatatat ggcaacatgg ttggcaccaa
     3841 ttatcactga tgtgtttaca ttagcaagtt tcgatgtggg gacagcagga ttagtaacta
     3901 tgttgttatg tggattatgg ccagtagggt tgtttgtttt attagcatct tactttggtg
     3961 taattggaat aggtggatta ggagttgttt tagtaggtgc ttctatctac atgaacaaag
     4021 tgaagaaagc ttaatcataa aattaaaata agaaagaaga gatcaatatg aaaaaattat
     4081 tagttatttg tggagcaggt catgctactt ctacaattgc agtagcaaaa ttatcaaaat
     4141 ggttggaaga agaaggatta acagatcaag tgaaaattta tcaatctaaa attgctgatg
     4201 agctaaataa aattgatgaa tatgatgctg tagtaagtac aacaattgtc cctgatgtaa
     4261 ttaaagctaa agtaacgaat ggcttgggct tattaacagg tattggtaca gatgccattt
     4321 atgcagatgt aaaagaaaga ttaggtgttt aatatgcgtt ttcatcatga cactttgact
     4381 attgaaacag tttcagggcg tccttcgtat catgatattc gaaaagaact tttagataca
     4441 gttgatacag caggtattga gaatggaatg ttagtaattt cgagcccgca tacaacttgc
     4501 tcactctttt ttgaagaaac gatgcatgac acaaactttt ttggtgatga ttatttacat
     4561 gtagacatca acaatgtaat ggaaacgatt attccaaaaa tgacgagtga aaatcaatac
     4621 aacagtccgg ggccaaaaca cattgatttt ggaacaagat tatctgatcc caattaccct
     4681 gcagaaaaat gggtcatgct aaataccgat gcacatttac gttcatctat ttatggaacc
     4741 aactcaatga ctttaattgt tcaagaaggt aaacttttat taggagaaat gggccgtgtc
     4801 tattttgtcg attgggatca actaagagag cgaactagaa caatcaatct catgattatg
     4861 ggagaataaa cgggggaata gagaatgaca attgctccat cattgttaaa tgcacctatc
     4921 gcagaagtta aagagttatt tgaaatctta aaagaaaaga atgttgatta tttgcatatt
     4981 gatgtaatgg atggctgttt tgtaccagat atggcttttg gaccaagtgt tattaaagat
     5041 attcgtccac taacagacgt tgtgtttgat gttcatttga tgattgatac accagaaaaa
     5101 attgtcacaa gatttgtaga agcaggagca gatattgtta ccttccacat tgaagctacc
     5161 aaacacgcaa tgaaggtcat tcagttagtc aaggaagcag gagcaaaagt agggattact
     5221 tttaatcctg caacaccagt cagttttatt gaaccagtat tatctttagt cgatcaagta
     5281 ttagtaatga caatcaatcc aggaacagag aataagcatt ttattcaaga gacagtagtt
     5341 aaaatcgaac agttagatgt aatacgcaaa caaaatgatt atacgtatga tattgaagta
     5401 gatggcaaga ttgataatca aacgattaaa gtttgttcta aagcaggggc ggatattttt
     5461 gtatcaggcg gtttcatctt caatgggaaa aataccccgc aagaacaaat tgataaacta
     5521 aatcaatcat tagaggaagt gaagtaaaag atcatgacca ataaagacca aaataaaaac
     5581 tatttagaag cgattatctt agaattacaa aataactcaa aacgtattaa ttctgtagag
     5641 ttagaacaat ttagtgagaa aattgttcaa gctaaacaca tctttctagc tggtgcagga
     5701 cgctctggaa ttgccatgca agcatttacg aatcgcttaa tgcatttagg tttttcagtc
     5761 agccttgtcg gtgaaattag ttcaccacat tcgcaacctg gagatttatt aattatctgt
     5821 tctggctcag gtgaaacagg tagtttaaaa aatttagcgg ccaaagcaaa tcaaagtggt
     5881 gtaagcattg ctttagttac catgaaaaaa gactcgtcga ttggtcaatt agcagattct
     5941 gttcttgtat taccaggtat taccaaagat gaaaatcaac gagaagaaga tactttttca
     6001 caacctatgg gttcaagttt tgaacaatta gcatttctca cctttgatag tttagtgtta
     6061 tctttaatgg ataaaacagg tgaaagctca gaaacgatgt ttgctcgaca tgcagatttt
     6121 gagtagtaga ttttaaagat aaaaaaccat tctctaaatg ctaattattc agcaaatatg
     6181 agaatggttt ttttatttga ttagacataa cttaataatt cagtagtttt gagcgtaagc
     6241 gtgtcataga atggtaccta aacacaaata gcccgatttg atacactcaa atcaggttat
     6301 ttgtggctta tattatttac agatttcttg tatctgctga ttccatggca aataagcgcg
     6361 tagcgcttca ggtgtcatcg aagacagatt gggaatctct gtaaaaagat gatttaaata
     6421 tttgcggatg tttaacccat tcgcaacagc tgtctggata atactcaata taattccatt
     6481 tgatctagcg ccttttaagc ttttagaaaa tagccagttt tttcgaccga tcactaactc
     6541 tttgatggca cgctctgctc ggttatttga aagttccaag cgtccatcaa gcaacacaat
     6601 ctgaagtccg tctttatgat tgactgcgta ttgaaccgcc tttccaagct gcgattttgg
     6661 caaataagca aaactctcac accaatgaaa aaattcagtc atcacaggct gcaacgtttc
     6721 cttcctcgct acaaaccttt cttctgcgct aagcttatta aaggtccgtt cgattcgaaa
     6781 catcttgtca cagaagtcta atcctatttt ggcatgactt tttggggacg gttgtttacc
     6841 caatgcttca aaaaactttc tgcgaacatg cgcccaacaa taaacattgt ttaccggcag
     6901 ctttccatag gccgcgtaac catcagtatg caagaaaccg ctaaatgatt ctaaaaaact
     6961 ttttggctca tcaacggaac gcgaatttgc gtgctcgtag agcacaactt gtttttcttc
     7021 gcttttacct gaagcatata accagtaaaa ggtcttttct ttatgagtat tcaatacccg
     7081 atagcttgtc tcatccgcgt gtaagacctc ctgattgctt aattcttgat gaaggcaatt
     7141 gtagattggc tctaaaacca tttcacttac cttgatatgc caattagtga tttttttacg
     7201 atcaagaggg aaaccaagtg catgccattc tttttcttgt cgatatgccg gcaccttttt
     7261 aacaaatttt tcccaaatac tctgtgtcac aattgaagag gaacctagac tattattgat
     7321 caacggttta ggaacaggcg cttttttgat ttttgtttct cctaatgctt cacattctct
     7381 gcaatgatag gcatgttggt agatgacttg tttttctata tgggcaggaa catacaatgg
     7441 ctcttctcta agccttgtcg caccgatatc atgtaaagta tgaccacagt cttcacacaa
     7501 acaatcggca ccttttaatt cataatgaat aggaacttca ggcagacctt ctaatgaaag
     7561 tgctttgagt cccttgcgtt ttctgcgttt aaaagaagat accgtaatgg gttcctggct
     7621 ttcttgtcca gtgtgctctg gttcattaaa agttgagtcg tctaataaat cgatttgccc
     7681 atctacgggt ggtgtttctt tttttcgtcc aaacaagcgt cgattcattt cagcaatttg
     7741 ttctctaaga agagtatttt cctgttgctg gatttcaagc aactgtgtta attgcttgat
     7801 ttgtacaaga agttcagatt ccatttttgt catttttaca ccaccattct agcgattttc
     7861 ttacatctat tataccattt tatgacaacg aaaaacagac aaaatccttg atttaacaag
     7921 gttttcgtct aatatatcgc accttttttc gtttctttta gcgtacattt ttcttcgatt
     7981 gaaaggccag tcagtaagac ttcttttctg gaacgcggcc attgaaggta cccactttca
     8041 aatcttttgt acattaatac aaatccattt tgatcctagt aaagagcctt gaagcgatct
     8101 ttcttcgtac cgcaaaataa gaaaagcgct tgatcgtaaa catcaaggtc atattcttct
     8161 ataacgaaag ctgctagtcc atcaattcct tttcgaagat ctgtttttcc acaaacgata
     8221 aaaatatgtt tcaatgcagt tgcatcaatg agcattggca ttcaactctt ttaacaaggt
     8281 atacaaaaga tatttatcca ttccattata aataaatatt tccttatctt ccgatttgat
     8341 tctgcaagct agttttggct tggtgtcaat ttgcgatttt tgagccgcac ttgaaaattg
     8401 aactggtaca atatcttttt tattcattcg tttttctcct tctatatttg atagtttaat
     8461 tatagaagaa agataatcgg cgtacgagat actatcctat gacacgctta catttaattt
     8521 aatattttgc ctcaaattag ccacactttt tatagaacta agaggaaaaa tgaagttttc
     8581 ttcctattaa tatagttgtt tgaaatctta aatatagcgt tttacgatgt aatgggaagt
     8641 atggtgaata aatcaactat gttcgtacga agcatttact caactaattt aatcgaatct
     8701 ttcaataaac aaatcaagaa atacagccac cgcaaggaac agttccaaaa tgaagagtcg
     8761 atggaacgtt tcttagtctc gtcttttgat acttacaacc aaaaattcct aggtcgcagt
     8821 cataaaggtt tccaacaggc cgaaggcgag ctcgaacaaa tgctgagtca accgatggag
     8881 aattagaaac aatctacagt agggaagaac cattgacaca aaattattga cgctcccaac
     8941 taaaagtgtc aaaataatga tgaaatcatt tagttcttat aaattagaaa agagaaaata
     9001 aatattccat atctacttta ttggatccgt aacatgacta aattctgaat actttttaaa
     9061 gcttatcatt tggtaaaact gaatataagt taattatata gactgaaaat tttgaatttt
     9121 cagaatagaa taacttaaaa gtactgacaa aattttttaa aggggcaata ttaatgttct
     9181 gagataatca aatcctaccg aaaatatcaa aaatccaatg tgacacaatc ggattgtgtc
     9241 tcattcgagg gaatcacaca atcccacgtg gctctaggca gaattgaatt tttgcttggg
     9301 gctttttcct tatattgatt ttgaatgaga cttattatat gttataatgc aattaagtat
     9361 cattggagag ggcgaagaaa atgaagacgg tagaacctat tcgagacaaa aaaaagatcg
     9421 atgcgatgaa ggcaatcttg gcttcgggaa aatatggcca acgaaatttg gttctttttt
     9481 cgattgggat caacaccgcc tatcgcattt ctgatttgcg tcaattgaag ctggccgacg
     9541 tgctggaaat ttcacgcggt cgcgtggtgg tcaaagatcg attagcgatg aaggaacaaa
     9601 aaacagctaa acataattcg gtctatattt ccaacaaatt gcgaaaaacg attttggagt
     9661 acgttcaaca ggaatttcct gatcaactcc ttcagcaaga ttttgacggt tatttgttcc
     9721 ctagtcgaaa agggacgaat gaaccgctca accgccaaag tctgtggcga atcattcatg
     9781 atgctggcac ggcaatcgga ttgaaagaca ttggcccaca ttccatgcga aaaacgttcg
     9841 gttactttct ctataaacag gggaccaaaa cagaaatcat tcagtccttg ttgaaccatt
     9901 cttctcagcg cgaaacattg cggtatattg gtattacaca agaagacaaa gatacagctg
     9961 taaaaagctt agatttataa tataaaagtt aagtttaaac atggatagtt ttaaattagt
    10021 agattgagtg ttgggaggaa agaatgagta cattatatat tataggaaac ggttttgatt
    10081 taagtcatgg tttaaaaact agatacactg atttttcaaa atgggttgaa aaaagtcata
    10141 gtgaaatatt cgataaaata gacacaatga taaatgaaaa taatgaggtg agaagtacag
    10201 ctgatgataa gataggttgg tttaattttg aaagtagttt gcatgagtta attcaaagtc
    10261 cagtctttga agattatgta gaagagtcta aggattatct cataggttat ggacatgaag
    10321 attggtcaga ttctgcccat catgattttc aaaatatggt ttatgattat gttgtttctc
    10381 tagaagaatt acaacaactt ttcaaggaat ggatacgcaa agaaatacag ccgacaatag
    10441 aacataaaat tccaaaatac caattttcgt ccgatgtact attctttaca ttcaattata
    10501 cagatgtttt ggaaattcta tacaagcaac cgaaagaaaa catatatcat attcatggca
    10561 gttatgacga tataataatc ggccactccg agaattttga caactttata ggagat
//
LOCUS       DAZKNV010000077        10353 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000077 DAZKNV010000000
VERSION     DAZKNV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.078"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            107..868
                     /locus_tag="ACG8M1_002427"
     CDS             107..868
                     /locus_tag="ACG8M1_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFQ0423092.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            1096..1290
                     /locus_tag="ACG8M1_002428"
     CDS             1096..1290
                     /locus_tag="ACG8M1_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423093.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            1559..1858
                     /locus_tag="ACG8M1_002429"
     CDS             1559..1858
                     /locus_tag="ACG8M1_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423094.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1955..2389)
                     /locus_tag="ACG8M1_002430"
     CDS             complement(1955..2389)
                     /locus_tag="ACG8M1_002430"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0423095.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(2621..3331)
                     /locus_tag="ACG8M1_002431"
     CDS             complement(2621..3331)
                     /locus_tag="ACG8M1_002431"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFQ0423096.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(3321..4181)
                     /locus_tag="ACG8M1_002432"
     CDS             complement(3321..4181)
                     /locus_tag="ACG8M1_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFQ0423097.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(4186..4824)
                     /locus_tag="ACG8M1_002433"
     CDS             complement(4186..4824)
                     /locus_tag="ACG8M1_002433"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFQ0423098.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(4839..5138)
                     /locus_tag="ACG8M1_002434"
     CDS             complement(4839..5138)
                     /locus_tag="ACG8M1_002434"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0423099.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(5181..6665)
                     /locus_tag="ACG8M1_002435"
     CDS             complement(5181..6665)
                     /locus_tag="ACG8M1_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFQ0423100.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(6685..7146)
                     /locus_tag="ACG8M1_002436"
     CDS             complement(6685..7146)
                     /locus_tag="ACG8M1_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0423101.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(7164..8231)
                     /gene="ulaG"
                     /locus_tag="ACG8M1_002437"
     CDS             complement(7164..8231)
                     /gene="ulaG"
                     /locus_tag="ACG8M1_002437"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFQ0423102.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            8449..9219
                     /locus_tag="ACG8M1_002438"
     CDS             8449..9219
                     /locus_tag="ACG8M1_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0423103.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(9492..10319)
                     /locus_tag="ACG8M1_002439"
     CDS             complement(9492..10319)
                     /locus_tag="ACG8M1_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423104.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         3178 a         2086 c         1668 g         3421 t
ORIGIN      
        1 atgcacatat aaataataag atgatataat caacaaagaa aatgtgattt ttttcactat
       61 attttatcac atgaaaattc attaagaaag taggaatcga agtattatgc acacaccaga
      121 agaaattatg gaactcagta ttcatcttgg aacaaaaaaa atacataaac ctatcttagc
      181 taaactgatt ttaggtttta tcggaggagc catgatttct ctaggttatt tggcatacgt
      241 acgagtctct gcttctatcc cagaatctat ggctagcttg actagtttag ttggtgcctc
      301 ggtttttcct atcggcctgc tggtcatcct tcttggcggt ggtgaattga tcaccggaaa
      361 tatgatggct gtggcgattg cctttatgga taaaaaagtc acattctcac agctggttaa
      421 gaattggtca gtgattactt ttgcaaatat tattggtgca attttcgttg cctatttctt
      481 tggacacttt gttggtttaa ctcattcagg tgtctatctc gaccaagtga ttcatattgc
      541 tgatcataaa atcgctgttt cttggtggca agcattaggc tccggaatag gttgtaattg
      601 gtttgtcggt ttagcgttat ggttatcata tggagcaaaa gatgcggccg gcaaagtact
      661 aacgatttgg tttccagtca tgatttttgt ggcaatcggt ttccagcata gtgtggccaa
      721 ctgttttgtg atacctgctg ccatatttga aggtcaagcg acttggttag aatttctctc
      781 gaattttatc cccgtttata ttggaaatat catcggcgga gctatttttg tttcaggttt
      841 ttattacgtt agttataagc atcattaaga ttgaaggtaa tgttcattcg agcattacct
      901 tcaatctctt tatatactat ttatatttta agaacaatag ccttttatta tatatattat
      961 tcaaattagt tatatcgagt gaaaaaaact ttcaaattga ttctttttat ttatcataaa
     1021 gatatagata cataatcatt ttcacttaca tatatttgaa tattaactaa aaacagcaag
     1081 aaagaagagg atcaaatgta ttatgtagaa gtaaaaacaa aaggcgtcaa aaacaaacaa
     1141 tatgtgaaag gtatcagtaa cgaatatcct ttacttggtt catggaaaga agctgctcct
     1201 ttttccaaac catgtgccat aaaaataaag aacgagctag aaaaagaact gacttgtggc
     1261 aaagctgttg tagatatcat cgaaaagtaa atccaatgta tagaaaggaa gatcacacat
     1321 gaaaagcgac gtacaaattg ctaagattat agaattagaa gaagaagacg cagtgttgac
     1381 aattgaaaaa aaataaatgt ttgtatacca tatgattatt tcaatatgta tcctggaatt
     1441 ggagatctcg tagagctata tcaagatgaa tcaaatatac ttgtcattca tcatgaaata
     1501 tagagactta taaaattgtt tatttttata atgtatcagt atagaaagga aataaaacat
     1561 ggattatact gttgaatttg acagtgaact acttaagcaa tttccacaag aagaacattt
     1621 catgtataaa gaagcaattt cccacaaagt gacagagtat ttggagcata atttttttcg
     1681 tataaagcca gtgcgtactc gttcggcaaa aggaatatac gagatgaaag tcaaaattaa
     1741 taaaaaaaat tatcgcatag catttgcttt aaaaaaaaat catgtgttca ttttttatat
     1801 tagttcgaat ttgcaaaaaa ttgtatttga taaagaggtg agtaaaaaaa taaaatagct
     1861 gagcattgga ggatagattg agtgatacta agtctatcct cttgtttttc taaagaacta
     1921 agctagaatt ttttcttttg tacgttatta tatgttattt gtcattacca aaaagcacct
     1981 tttttcttct agtatctatg acataagaaa taccacccat ttcctttact tgaacaaatc
     2041 ctactgattc ataaaatttt tttgttttct cagtatcatc tgtcaataat tcgatttgga
     2101 ctggtccata actagtgatc ttctccaaag cttcattcaa aagcactttg cctattcctt
     2161 ggcgctgata cctcggatga atgaggatat cttgaataaa tgcgatcgtc gcaaaatcag
     2221 tgatccaacg aacgattccg ataatcttcc cttccccatt acgctttatc agagattcag
     2281 attgttcaaa tgctctagct aaccttgcag tgtcttttgt gtaattcgtc caaccaacgc
     2341 tcttatataa ttcagaaatc tcatcgatca taagggaatc aatattcatt tttttcttcc
     2401 tttcttatac aattctccct ctaataatac agttctttga ctatttaatc tatcacatat
     2461 aactctcctg taaagattct ctcgattcct taaaatctct ctttcctttt agaatgcatc
     2521 ctttttgata aataaaaagg ttgtgataaa ttttcttcac aacctctgtt tctctctatc
     2581 aagtgttatc ttttaatttt ctacccttac cctagcatct ctattgcccg tagtatgcat
     2641 actttccatg tttgcgaaaa taatgtttat ctagtaaata ttgcgggatt tcacatatat
     2701 tggggttgat cagctcgttt tctttggcca tcagacaaat ttcatctaag atcaaactgt
     2761 tttctactgc tttcataggt gaatcccccc atgtgaacgg tccatgtcca tagacaagta
     2821 ctccagggac ttcgtttgga tctaattttc tttccttaaa cgtctcgaca atcacattcc
     2881 ctgtatgaac ttcgtaagct tctcttactt cttctttcgt taattggcgt gtacaaggaa
     2941 ccttaccata aaaagcatca gcatgagtcg tgccataagc tggcaaatcg cgtcctgctt
     3001 gcgcccacat gacggagtgc gtggaatgag tatgagtaat agcagttata tcttcaaaag
     3061 tttgatacaa aacaacatgt gtggggagat ctgaagatgg ttttaagcta tcttcttcta
     3121 ttatatttcc cgacaaatct gttaccacca tttgatctgc ttgcatgcat tcatatctga
     3181 caccgcttgg cttaatgacg atgactccta gctcacggtc cacttcactc acattgcccc
     3241 aagtcaattt gactaatccg tatcgcggca atgccagatt tgcttcaagg acacgttgct
     3301 tcattgctgc aattttttct tcacaagaca tcatagccag cctccttcaa tttagaactt
     3361 aagtagtctt ttgcctgctg gatttctctt cgaaagtctt ggcttttttc actccacatt
     3421 tcaatcagaa atgttccatc ataatctaga cgtttcaaat gtcttaataa tccaagaaaa
     3481 tcaacacaac cgctaccaaa aggaacatca cgaaactggc ctgaatattc ttttgttaca
     3541 gggtaagtat cttttaagtg gatagcagtg atataatcga tccctttctc aagttctcga
     3601 gccggattat tttccggcca tgcggacaaa ttgcctaggt ctggatatac ttgtagaaaa
     3661 ggggaatgaa tctgttcttt gatttctaaa aattttgaaa tggagttcat aaatggatca
     3721 tccatgattt ccacggaaag aatgatgcca tatttagaag cttcctttac gctttctttt
     3781 attccttcga taaagtcttc tctggaattc attgatttct cttcataata aacatcgtat
     3841 ccagctattt ggattacttt gacgcttaga ttatgcgcca aatggattgc ttttttcatt
     3901 agttgtttcg ctgctttttt cttttctgga tcagcagaac caaacggaaa tcgccgatgc
     3961 gcacttaaac aaatcgaatg gatacgtaca ccggagctga acatctcttc tctcagctca
     4021 gctatctttt cttcagacca atctaatcgt gctaaccgct catccgtctc atcaatcgac
     4081 atctcgataa aatcgaagtc catttctttt acaagggaaa aacgttcttt ccatgaaata
     4141 tctttgggta atgctttttc ataaatccca atttgagcca tttccttacc cccagatacg
     4201 aatgatctca tctttgaagt tttgtgcggc cttcatcgga tcatttgctg ctgtaatacc
     4261 acgaccagtg ataaaggtat acacatcgat cccttcaaat aagtgtaatg tgtgtggatt
     4321 taatccacca gttacagaaa cattaaagcc tagttcaatc agttttttga tcttcgataa
     4381 atctttttca ccccaagttt caccagataa cagcgcatca cggctttgat ggtagattac
     4441 ctgccggata ccgatgttat gccaatccat ggcttgttca aaagtccaat tgccgtagag
     4501 ttctacttgc aattcaccta tttctttttg tgctgcctcc atagttggaa tcgttgcaca
     4561 acaaatgact gtcatccagt ctgctcctgc ttttgcaaca ttactcgcca ctgttcctcc
     4621 agcgtctgca catttcgtat cagcgactag ttttttatct gggaacatac tgcgaataca
     4681 gcgaatcgct ttttgtcctt cctgtaagca aagaattgtg cccacttcaa taatatctac
     4741 tacatcacca actttcataa catctcctaa tgcatgttct aagtcattgt gatctaacgc
     4801 aatttgcaaa ttcggcctgc tcatcttagt tccttccttt acttgttttt ttggtaccac
     4861 tttgtttcag caaatttttc actgatttct ttggctgaca tcacattttt gataccgata
     4921 actgtaactt cttttttctc tgcctgagta aacatattca aaaaattgac tggcgtaaaa
     4981 actacatcgt attggccagc tgaacttttt ccctctgaaa tggcacaatg atggattttg
     5041 gtaattggta cgtttagttc tttcattgct ttttccacac ttctcatcat catcaagctt
     5101 gttcctgatc catttgcaca cgatactaaa attctcatct taatccctcc attatgagtg
     5161 ttgtctaatc agattttctt ttatactctc tgcttttctg catatgtgtc atagtcttct
     5221 acaatcaaaa aataaccctc aggatttttc cgatattgta actgcggaat agccaataaa
     5281 ccaatgacaa ctacggcaat tccagcataa cctaggactt tcatgattac tgtaaacaat
     5341 ggccaagctg ttgcccagtc gaacatcccg atataaccac catatgttga catcccaatc
     5401 catgtagcga ataatgctga accgcctact tgtatgattc ctgaaagaaa cgggaacagg
     5461 caagcggctt tgaatccacc tcggttattg gcataaactg ctataacggc attatcaaag
     5521 aacaacggaa tgaaaccggc tatgacgatc gttggtgatt tcaataaaat cagtaaacca
     5581 atcatcaaaa actgtcccaa agcaccaaac aagaacccaa tcgttaccgc atttggcgaa
     5641 ccaaagccaa aagtagcagc tacgtcaatt cctggaacag ctcctggtaa aattgtgttt
     5701 gagattcctt ggaaagattg agttagttca tcgacgaatg tccgaacacc taattgcaag
     5761 atcgccagat ataccgcaaa atttaaagaa gtcgtcataa tgtagaataa gaaactctgt
     5821 ccttcttgca tgaattgcgc ttgaatcaaa taatctttgc ctagtacaat cagaatgatc
     5881 ccaaagaaaa atagcatgag taacgaagta gcaaccatat tctcattgaa aatcgacaag
     5941 aatcctggta atttgatatc ttcgattttt ttgtcttgct tgattgatct atttttcttt
     6001 tcatcccgct ttttcatcca ctcagctaat tttgcaaata taaagattcc gaacatttgc
     6061 tgatgtgcca ctgcaaatcc ggcaccttct gtcaattcct gcgtgattcc tactgttaag
     6121 ttagaagcta ctgcccaata acaacctaaa atcagtccca taaaaatcaa tacttgtatc
     6181 ctacctagat caggaaagca aaacagtaaa atccaaaaag cggtagctgc ttgttgaacc
     6241 tgaacgtttc cggtagtgaa aacggaacgc agtttcgtat atttctgaaa acggactaat
     6301 aagatattta aaacaaatgc aatcagtaat aaaatcatca catctccaaa ggtacggcca
     6361 aatgtctcca ttaatccagc atccacagca ttttgtccaa aataaggatc tgtaaccatg
     6421 gcatccaaat tgaaccgttc ctttagtcca accaaaatcg gccgaaaatt attgaccaaa
     6481 ccaccagagc caacagtcaa aataaagtaa ccgaccgttg cctttaagaa tccagcgatg
     6541 cattcatgaa gcgggcgttt cagcaaaata tagcctaata acacgataaa accaatcagg
     6601 tatgctggct gcgtcaagat atttgttgca aaatacgtcc aaatgcttaa caaaaattcc
     6661 cccatctttt ttctcctcta tcaattaatt atattctgcc atcacaactt ggtaatcatc
     6721 gatggagttc gtagagatga gacgctcaac caatccatct gtcattaata attcggataa
     6781 tttttggata ttttctagat gttcttctgg atcttttgct gcaagtgtaa aaaacaaact
     6841 agccgttttc tcctcatcct ccccttcact ttcaaaacgg attggctgtt tcaacttggt
     6901 aaatgaaata gctgttccaa aaacaccatc acttttttct gaagaatgcg gcattgctac
     6961 ttgaggtgcg atcacaatat aaggaccgta tttttctaca caatggatga tctcctccac
     7021 atacgtttca tcaataattt ccttatcgat caatacaaga cagctttcgg cgatagcttc
     7081 acgccaatcc gtgatttctt tatctgggta atgaatcaat tgatggtcaa aaaagtattt
     7141 cagcaagaaa ctccccttct ttcttataaa aacgacggaa acggtgtatc attttcaatc
     7201 gagaagacat cttcaaatcc tcgataaaaa ttaaactcaa gatcatcttt gtttgtcgga
     7261 tagatgaatt tcccgcctac ttgccagata taaggtttaa atccatactt caggcgatcc
     7321 tttttgaatt tccaaatttc agtgatctct tttgaatcag ccataaaatt agaccaaata
     7381 tcgtagtgga caggaatcac tacttttgca ttcaatgact ccgccatgcg cagcatatca
     7441 acagaagtaa ctttgtctgt tatccctcgt gggttttcac cataggcccc taaacagaca
     7501 tcgattttgt gttcattacc atgtttggca aataaattgg agtaatgtga atctcctgca
     7561 tgataaagat tccctcctga tgtttcgaat aaatagttta ctgcaatttg atccatctcc
     7621 tgaggcattt ttccttttaa tacctcttct ggatcttcac aagtgaccaa cgctgtccga
     7681 tcaaacgctt ctaaagctac tacattgatg tctttgattt tgactgcatc acctggcttt
     7741 actgtaatcg ttttttcttc aggaattccc catttttgcc acgtgcgaac cacttctttt
     7801 ggcccaatga atgttgcttc aggacaattt tgatgaactg ctgcggctgt atggatatct
     7861 agatgatcgg aatggatatg tgtaacgatt aaagcgtcta cattttttat cgcaaaagga
     7921 tcgattacga aaggctgagt acgtaaatta ggctgcatat tttgaacgcc actcatacgc
     7981 atcatctgat ggcctttttt catcatgcca ttcccatgac tacgttttcc cgtcccacac
     8041 catagatcac ataaaatatt cgttccttca tgacttttca gccaaattcc cgtacagccc
     8101 agccaccaca tagcaaaagt tccaggatcc actacttctg tttcgatttc ttcattcaag
     8161 tatgtgcccc actcaggaaa tgtttctact aaccactttt cttttgttac ttcattgaca
     8221 gttttactca tttgcttgct ccccccatat cgttgttcca acttacaagt aaatattaat
     8281 gtgtatcagc atccatggaa acccttttat atgaccgttt gttttttata tgattttctt
     8341 tcagtaatca atgattgttt cagtataata aagacagata tgaatgttta aatgaacaac
     8401 tagtcaaata aatccatgga tcaagatgtc cctcaggagg caaaagtcat gaaaaactca
     8461 cttgtcaata ttgaaaaacg tcaaaaagaa attttggaac tgcttcagca gactgaacaa
     8521 ctatcaactt tcgaattagc tgaatccctt gatgtatcta ttagtacgat acgaagagat
     8581 ttaaatttat tagaagaaaa aaacgagatc atacgcaatt acggttattg ttcttataat
     8641 tacaaaaacc agactgattt tgatcaatct ggtcctgaaa ggattaaaca agcgattgcc
     8701 agagaagcta gtaaatacat taacgattat gatacgctgt ttatcaattc tagctcgact
     8761 gcgttgaaaa cactggattt tcttcaatct aaccatttga cagtcattac aaacaacgtg
     8821 aaaatcaatt actctccgca caaagataat tgtagttata ttttaactgg tggagagatg
     8881 cgctttccaa aagaagcact agtgggcgac atcgcattaa atacgatttc ttcagtcaat
     8941 gcagacattt gtatcattgg ctgtagcgga gtcgatgtag tacatggggt cacaacaaag
     9001 atattaaatg aatcaacgat caacgaaatg atggtcaaca agacaatcaa atgtaagatt
     9061 ttagtcgctg atcatcgaaa aatcggactg acatcaaagt tcaagattgc tgatatttca
     9121 gtctttgatt atttgatcac tgataaattt tgttctgaaa aagtattaga ggagatcaga
     9181 aatacgggga taaaaaccat tcaagtagat tcattttaag aaccaggacg taaatatgta
     9241 aataggatta tcaaaaaaat gaataacaaa tttatcgata aatgaaaaac acgctacgct
     9301 caaattgata aaggaatccc aagatgtgtc catccaatcg ataccatcat aatctattgc
     9361 ttcttttata accgttatat gttgcctaaa taggaatcaa acaatatcga aaaaaggagg
     9421 tatgacaaaa gtcacacctc cttttttcga ataaacggta ttcaaatcag aacactgatt
     9481 tcacaaccac tttatttcag gtcgttttca atcaccttta ccgcgtaatc atttccgttg
     9541 aaacgcgcta ttttttttgc gtccatatat ctttctaaat aatcatcttc tcctaattgc
     9601 ttatggcaag aagcaatttc ataaagcaag tattccaatg cataagtcga tttatgtttc
     9661 ttattatact caataccctt ctcacataat tggattgctt tatcataatc ctcgatttta
     9721 cggtaatagg tggcgatatc ataatataca atgcagacca tcagattatc aaaatcagtc
     9781 tcactcaata ttttaagtgt acgctccaca taaactttcg caaaatctaa ttctcctttt
     9841 gacaagtaga tcattgccac gtttgcagct gcttgtaagt gatggatatc tgtttcggtc
     9901 gtttgttcca acacttgatt aaaataaaat aatgctgcat ctggtttttt cgcataaaga
     9961 tgatcaagca gtccttgata aaataaaatt tgatttaaaa gatcagaatt acttactttt
    10021 tcctgatcga tcgtttgtaa aattttataa gattcttggt attttgatac agaattcaat
    10081 gattgaatct catttatttt tttcctgatt ttgtcttctt ctgtttctac taatatatcg
    10141 gagatctcga cattcagctt tttgcaaagc gcacttaaga tattgatgcc tggcgacata
    10201 ttcttgtttt cgatattgct gacagttgct tgttcacaaa tgccttctgc taattgtact
    10261 tgtgttaacc cctttttctt tcggtattct tttagtaatg ctccatctac tttaatcaaa
    10321 acaatttcct tccctttaaa aaattatttc tcc
//
LOCUS       DAZKNV010000078         9955 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000078 DAZKNV010000000
VERSION     DAZKNV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.079"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..439)
                     /locus_tag="ACG8M1_002440"
     CDS             complement(<1..439)
                     /locus_tag="ACG8M1_002440"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0423105.1"
                     /translation="MEEFGIDSISRTEALDFQADYEYELDQITMIPEIHQLLLALHKN
                     RIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGAAENSYEGNVKNLQSY
                     QNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRHK"
     gene            complement(662..1429)
                     /locus_tag="ACG8M1_002441"
     CDS             complement(662..1429)
                     /locus_tag="ACG8M1_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0423106.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1917..2342
                     /gene="lacA"
                     /locus_tag="ACG8M1_002442"
     CDS             1917..2342
                     /gene="lacA"
                     /locus_tag="ACG8M1_002442"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFQ0423107.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2359..2874
                     /gene="lacB"
                     /locus_tag="ACG8M1_002443"
     CDS             2359..2874
                     /gene="lacB"
                     /locus_tag="ACG8M1_002443"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFQ0423108.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2885..3817
                     /gene="lacC"
                     /locus_tag="ACG8M1_002444"
     CDS             2885..3817
                     /gene="lacC"
                     /locus_tag="ACG8M1_002444"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFQ0423109.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTVSHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3820..4800
                     /gene="lacD"
                     /locus_tag="ACG8M1_002445"
     CDS             3820..4800
                     /gene="lacD"
                     /locus_tag="ACG8M1_002445"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFQ0423110.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4828..5145
                     /locus_tag="ACG8M1_002446"
     CDS             4828..5145
                     /locus_tag="ACG8M1_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0423111.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5145..6851
                     /locus_tag="ACG8M1_002447"
     CDS             5145..6851
                     /locus_tag="ACG8M1_002447"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFQ0423112.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTVLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            6993..8399
                     /gene="lacG"
                     /locus_tag="ACG8M1_002448"
     CDS             6993..8399
                     /gene="lacG"
                     /locus_tag="ACG8M1_002448"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFQ0423113.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8422..8694
                     /locus_tag="ACG8M1_002449"
     CDS             8422..8694
                     /locus_tag="ACG8M1_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HFQ0423114.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            8715..9614
                     /locus_tag="ACG8M1_002450"
     CDS             8715..9614
                     /locus_tag="ACG8M1_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFQ0423115.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3138 a         1678 c         1996 g         3143 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagtagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttc gtgtatttag gaaaagcaac atcagaccaa catctgaaac gtttgtaaat
      541 gttatctatt tgttggatat caatcgttgg aaaacatttc tcaacgctac ttttaaaggg
      601 gagttgatgg tcataaagag tgtcatcaag gtcaaaaaca atatttttat aagtcataat
      661 tctagtccgc ttttaaaata gtagtgtact ggctaaattc ctctaagtgt tgagggctaa
      721 tctggttatc tgtaatgatg gtatcgagtt gatctagatt atagaagtta aagaaatcgt
      781 atcgatcgaa tttagtactg tctactaata agaatttttc tacagcattg tttagggcaa
      841 gttgttgaat cacaccttcc ttgtcactat atgtagcaat agaattatgg gtaacagcat
      901 ttgcactaac aaaagctttg gcaaatctaa ttgcttttaa atttgtcgaa gccattgaac
      961 ctacaaaagc tccagttatt tctctatatt caccgccaag aagcaataaa tcaatggttt
     1021 cgctatcatt tagaatcaag aacacaggga gactatttgt aatgacacga attttataac
     1081 ctttacgacc tttcaattct aatgccagtt gttcaagtgt agttccgggt ccaataaaaa
     1141 tagtatcgcc atctttgatt aaagagcagg cttttttagc aatgtcaatt ttttcttttg
     1201 tatttagact tttcttctcg atatgtgtct tttcaagtgg ctttttagag gaaagtaatt
     1261 gtgcaccacc atgagtacgt gttaaaagtc catcagcttc tagagcatca aggtctctac
     1321 gggctgtcat atcggaaata tctagttcat ctattatttc ttttatggtt atggtcccat
     1381 caatctttaa catatctaaa attttttcta atcgtcgttt tttgttcata tgaagaccct
     1441 tctttcataa agtaattttt ttccaaagat aattctcttt taattgtatc ataaaagaca
     1501 atattttcaa ggtaaaacaa acaatttcaa acaaaaacaa atgttagatg atgaaataag
     1561 aacagtggat tgacgtatat tagcttaggt cagattttgt ataagacgaa aataaagtag
     1621 gacctcttaa tcagtaagtt atagaaagta aaagactttt gtaatacttg aatagatatt
     1681 tcacgtccat tttgtgatgg attaaatgaa caaaaatgaa caataattta acggtgttat
     1741 ctatttttta aaaaaacaaa taaaaaaaca aaaaataaac aaaaaagtgt tgctttttgt
     1801 ttgaatgctt gatattatat aaacaaagaa atgatgaaaa cgttttttcg aacattttgc
     1861 aaaatgtttt ctacttctac gtagcatttc tttctaaaat ttaggaggtg gtcaaaatgg
     1921 ctattgttgt tggtgcagat ctcaaaggta cgagattaaa agatgttgtg aaaaattttc
     1981 ttgtagaaga aggttttgag gtaattgatg tgactaagga cggacaagat tttgttgatg
     2041 ttaccttggc agttgcctct gaagtaaata aagatgagca aaacttaggt attgtaattg
     2101 atgcttatgg agctggtcca ttcatggtag caactaaaat taaaggtatg gttgcagcag
     2161 aagtttcaga tgaacgctca gcttatatga cacgtggaca taacaattca cgaatgatta
     2221 cggttggcgc tgaaatcgtc ggtgatgagc ttgctaaaaa catcgctaaa ggtttcgtca
     2281 atggtaaata tgatggcgga cgtcatcaaa tccgagtaga tatgcttaac aaaatgtgtt
     2341 aaggaaagga gttaaggaat gagaatcgca attggatgtg accacattgt cacagatgaa
     2401 aaaatggcag tatcagaatt cttgaaatca aaaggacatg aggtccttga tttcgggaca
     2461 tatgaccacg cacgtactca ctaccctatc tatggtaaaa aagtcggtga agcagtagta
     2521 agtggtcaag cagacttggg agtatgtatc tgtggtacag gtgtcggcat taacaatgca
     2581 gtcaataaag ttccaggtgt tcgctcagcg ttggttcgtg atatgacatc agctatatat
     2641 gcaaaagaag agttaaatgc gaatgttatc ggtttcggtg gaaagattac tggtggtctt
     2701 cttatgaatg acatcattga agctttcatt gaagctgagt acaaaccaac agaagaaaat
     2761 aaaaaattga ttgcaaaaat cgaacacgtt gaaacacata atgcacatca agcagatgaa
     2821 gatttcttta cagaattcct tgaaagatgg gaccgtggtg actaccacga ttaaggtata
     2881 acaaatgatt ctgacagtca cactaaatcc ttcagtagac atctcttatc ctctagaaac
     2941 attgaaaatt gatacagtga atagggtgaa agatgttagt aagacagctg gtggaaaagg
     3001 cttaaatgtt actagagtct tgtatgaatc tggtgataaa gttactgcta caggtttctt
     3061 aggtggtaaa attggtgaat ttattgaaag cgaattagaa caatctcctg ttagtccagc
     3121 tttttataaa atctcaggaa acactagaaa ctgtattgct atcttacacg agggtaacca
     3181 aacagaaatt ttggaacaag gaccaacagt ttctcatgaa gaagcagaag gttttcttga
     3241 ccactatagc aatcttatta aacaatcaga agttgtgaca atttcaggaa gtttaccttc
     3301 aggacttccc aacgattatt atgaaaaact tatccaactt gcttcggatg aaggagtagc
     3361 agtcgttttg gattgttcag gtgcacctct tgaaacagtt ctaaaatcgt cggctaaacc
     3421 tactgccatc aaacctaata atgaggaact ttcacagttg cttggaaaag aagtaacaaa
     3481 agatattgaa gaactcaaag acgttcttaa agagtcactt tttagtggta tcgaatggat
     3541 agtggtctca ttaggtcgaa acggtgcctt tgcaaaacat ggtgatgttt tctataaggt
     3601 agatattcct gatatcccag ttgttaatcc agtcggatca ggggactcaa cggtagctgg
     3661 tattgcatca gctttaaata gtaaaaaaag tgacgctgac ttattaaaac atgcgatgac
     3721 attgggtatg ttaaatgctc aagaaacaat gacagggcat gtgaatatga ctaattacga
     3781 aacactaaac tcacaaattg gagtaaaaga ggtataaaaa tggtacttac agaacagaaa
     3841 cgcaaatctt tggaaaaaat ttcagataaa aacggtgtta tctcagcttt ggcatttgac
     3901 caacgtggtg ctttgaaacg tttgatggca cagtatcaag atacagaacc aactgtagct
     3961 caaatggaag aactaaaggt tttggttgct gatgaactta caaaatacgc ttcttcaatg
     4021 ttgcttgacc ctgaatatgg acttccagca acaaaagcat tggataaaga agcaggtctt
     4081 cttcttgcct atgaaaaaac aggttatgat acatcaagta caaaacgttt gcctgactgc
     4141 ttggatgttt ggtctgcaaa acgtatcaaa gagcaaggcg ctgatgccgt taagttcttg
     4201 ctttactatg atgtagacag ctcagatgaa cttaaccaac aaaaacaagc ttatattgaa
     4261 cgtgttggtt ctgaatgtgt cgctgaagat attcctttct tcttggaaat ccttgcttat
     4321 gatgaagaaa tctcagatgc aggttctgtt gaatatgcaa aagtgaaacc tcgcaaagtc
     4381 attgaagcga tgaaagtttt ctctgatcca cgctttaaca ttgatgttct taaagtagaa
     4441 gtaccagtta acgttaaata tgtcgaaggt tttgctgatg gtgaagtggt ttacagtaaa
     4501 gctgaagctg ctgacttctt taaagcacaa gaagaagcga ctaaccttcc atacatctac
     4561 ctaagtgcag gtgtatctgc taaattgttc caagaaacat tgcaatttgc tcacgactca
     4621 ggtgccaagt ttaatggtgt gctttgtgga cgtgctactt gggcaggatc tgtagaacct
     4681 tacatcaaag aaggtgaaaa agcagcacgt gaatggttgc gtactactgg attcgaaaat
     4741 attgatgaac ttaacaaagt tcttgttaaa acagctagtc catggactga taaagtatag
     4801 taaaaacata aaacggagga tattgttatg aacagagaag agatgactct cttagggttt
     4861 gaaattgttg cttatgctgg agatgctcgc tctaaacttt tagaagcgct taaagcggct
     4921 gaaaatggtg atttcgctaa ggcagatagt cttgtagtag aagcaggaag ctgtattgca
     4981 gaggctcaca attctcagac agctatgttg gctcgagaag cttctgggga ggaacttcca
     5041 tacagcgtta ccatgatgca tggtcaggac cacttaatga ctactgtctt attaaaagat
     5101 gtgattcatc acctcatcga actttataaa agaggagcaa aataatgcat aaactcattg
     5161 aacttattga gaaagggaaa ccgttctttg agaaaatctc tcgaaacatc tatcttcgtg
     5221 ctattcgtga tggatttatc gctggtatgc cagtcatcct tttctcatct atctttatcc
     5281 ttattgccta tgtcccaaat gcttggggat tccactggtc aaaagacatt gagaccttct
     5341 tgatgactcc ttatagctat tcgatgggta tcctagcatt ctttgttggt ggtactaccg
     5401 ctaaagcttt gacggactca atgaaccgtg acctacctgc gaccaatcag attaacttct
     5461 tatctacgat gctagcgtct atggtagggt tccttttgat ggcagctgag cctgcaaaag
     5521 aaggaggctt cttgacagcc ttcacgggaa caaaaggtct tttgacagca tttattgcag
     5581 cctttgtgac agttaatgtt tacaaggtct gtgtgaaaaa taatgttact attcgtatgc
     5641 ctgaagaggt tccaccaaat atctctcaag tatttaaaga cttgattcca ttcactgtag
     5701 cggttgttct cctttatgga tttgaactca ttgttaaggg aactcttggt gtaaccgttg
     5761 cagaatcaat cggtaccgtt cttgctcctc tcttctcagc tgcagatggt taccttggaa
     5821 ttacacttat ctttggtgct tatgccttct tctggtttgt tggtatccac ggtccttcaa
     5881 ttgtcgaacc agcaatcgct gctatcactt atgccaatat cgatgccaac ttgcatctta
     5941 tccaagctgg acaacatgca gataaagtta tcacttctgg tactcaaatg tttattgtta
     6001 ccatgggtgg aacaggagct acattgattg ttccattctt gttcatgtgg atttgtaaat
     6061 cagaacgtaa ccgtgccatc ggacgtgcct cagttgttcc aacattcttt ggggttaatg
     6121 agccaatctt atttggtgca ccaatcgtat tgaatccgat tttctttgta ccgttcattt
     6181 tcgctccgat tgtcaacgtt tggatcttta aattctttgt tgacacattg aacatgaact
     6241 cattctctgc caaccttcca tgggttactc ctggtccgtt gggaattgta ctcggtacta
     6301 acttccaagt tctatcattt atcttagccg gactcttggt agttgttgat actatcattt
     6361 attacccatt tgttaaggta tacgatgaac aaattcttga agaagaacgt tctggtaaaa
     6421 caaacgatgc tcttaaagaa aaagtagctg caaacttcaa tactgctaaa gcagatgccg
     6481 ttcttggaaa agcaggcgtt gctaaagaag atgtagcagc aaacaataat atcacaaaag
     6541 aaactaatgt ccttgttctt tgtgcaggtg gaggtacaag tggcttgctt gccaatgcct
     6601 tgaacaaagc agcagcagaa tacaatgttc cagtcaaagc ggcagcgggt agttacggtg
     6661 ctcaccgtga aatgttgcca gagtttgact tggttatctt ggctccacag gtcgcttcaa
     6721 acttcgatga tatgaaggct gaaacggata aattgggcat taaacttgca aaaactgaag
     6781 gagctcaata tatcaaattg acacgtgatg gacaaggtgc tcttgcattt gttcaacaac
     6841 agtttgatta ataaatttgt aaaagttatt tgagacgaga ttattctttc agttccttat
     6901 aatattgtta accatatcat tgcatttcat ttccttggtt tccggaactc agaatatcgt
     6961 ctcaaatgct ttttttgaaa ggatttatag ttatgactaa aacacttcct aaagatttta
     7021 tttttggtgg tgctacagct gcttatcaag cagaaggtgc gactcacacg gatggtaaag
     7081 gcccagttgc atgggataag tatcttgaag acaattattg gtacacagca gagcctgcaa
     7141 gtgattttta ccataaatat cctgttgatt tagaattagc tgaaaaatat ggcgttaatg
     7201 gtattcgtat ttcaattgcc tggtctcgta ttttcccaac tggctatggc gaagtaaatg
     7261 aaaaaggtgt tgaattctac cataatcttt ttgccgagtg ccacaaacgt catgttgagc
     7321 cattcgtgac tttgcaccac tttgacacac cagaagttct tcactcagat ggagatttct
     7381 taaaccgcga aaatatagaa cactttgtag attatgccgc tttctgtttt gaagagttcc
     7441 cagaagtaaa ctactggaca actttcaatg aaattggccc aattggagat ggtcaatact
     7501 tggttggtaa attccctcca ggcattcaat atgatcttgc caaagtcttc caatcacacc
     7561 acaatatgat ggtttctcat gcacgtgctg tgaaattgta taaagataaa ggttataaag
     7621 gcgaaattgg tgtagtacat gcgttgccaa ccaaataccc ttatgatcca gaaaatccag
     7681 cagatgttcg tgccgctgag ttagaagata tcatccataa caaatttatc ttggatgcaa
     7741 cctaccttgg acactattca gataaaacga tggaaggggt caaccacatc ctagctgaaa
     7801 atggtggaga acttgatctt cgtgatgaag acttccaagc acttgaagca gctaaagatt
     7861 tgaacgattt ccttggtatc aactactaca tgagtgattg gatgcaagcc tttgatggtg
     7921 agactgaaat cattcacaat ggtaagggtg aaaaaggaag ttctaagtac cagattaaag
     7981 gtgttggtcg ccgaatcgca ccagattatg tgcctagaac ggattgggac tggattattt
     8041 atcctgaagg cttgtatgac caaatcatgc gagtgaaaaa tgattatcca aactacaaga
     8101 agatttacat cactgaaaac ggtcttggat acaaagatga gtttgtagat aataccgttt
     8161 atgatgatgg tcgtattgat tacgtgaaga aacacttgga agttttatca gacgcaattg
     8221 cggatggtgc aaatgttaaa ggttacttca tctggtcact tatggatgtc ttctcatggt
     8281 caaacggata cgaaaaacgt tatggactat tctatgtaga ctttgacacg caagaacgct
     8341 atcctaagaa atcagctcat tggtataaga aagtagcaga aactcaagtg atagagtaat
     8401 attacttgaa aatgtaaaaa attgttatcc gatactttag aaaaagtaca acacttattt
     8461 agaccaggct ttgaaaaggt atatattgtt agtttcgaag attgtcctat gattcctgag
     8521 cttgaagcta ccccgttgct aaaatgtggt aaatggtatg tttcaactgg aaaagagtgg
     8581 atttgccatt ctgatttaga gttatcagca tttgaatggg aatttttaca atcactcgat
     8641 gtagaaatac gtgagactat tcacttcgag gtaaattatt tgcctttcca ataataaaaa
     8701 gaaaggaatt agttgtgact atcgaattaa aaaacgagta tcttactgtt cagtttaaaa
     8761 cacttggtgg tcaactgact tcgattaaag acaaggatgg gatagagtat ctctggcaag
     8821 ctgatccaaa ttattggaat ggacaggcgc ctattctatt tcctatctgt ggtagtttac
     8881 gaaatgattg ggctatttat agacctcaag aaagaccttt ttttacaggt cttattcgta
     8941 gacatggttt tgttcgaaaa gaagaattta ttctggaaga agtcaatgat aatagcgtga
     9001 cctttagtat taaaccaaat gctgagatgc ttgataatta cctatatcag tttgaactga
     9061 gagttgttta taccttgaat ggtaaatcaa ttagaaccga atttcaggta acgaacttgg
     9121 aaatggaaaa aacaatgcct tactttattg gagcccatcc agcattcaat agtcctttag
     9181 tagaaggtga aaactatgag gattattata ttgaatttag tgaggttgag tcttgctcga
     9241 taccaaagag ttttcctgag acaggattat tagatttgca agatcggaca ccttttttgg
     9301 aaaatcaaaa aattctcgat ttggactact cacttttttc ccatgatgcc attacacttg
     9361 accagctcaa gtctcgtagc gtaacgcttc ggtcaaggaa gtctggtaaa ggtcttcgag
     9421 tagattttga tgattttccg aacttgattc tgtggtctac aactaataaa agtccattca
     9481 ttgctttgga accttggagt ggtctctcca cttcacttga agaaggtaat ttcttagaag
     9541 ataaaagaca ggtaacgaaa atttcacctc aagaaacttc tagaaaaatc tatgatatta
     9601 ctatccttaa ttaaaatttg ttattatttg agtcttcaat aagatttgaa tactcttacc
     9661 ttgtgatgat agattggtct tctccgtgcc agtcttacat cgcaaggttt ttaagttttt
     9721 tgtgggtcta tgtcaactgt agtgggtgac gaaaagctaa tatctaaaga cagtctggta
     9781 gtaaaaaata agattattta ctacttcttg atttaaaata atagtggagc cattaatttg
     9841 tggcaaattt aatttaatat tttgcctcaa attagccaca ctttttatag aactaagagg
     9901 aaaaatgaaa ttttcttcct attaatatag ttgtttgaaa tcttaaatat agcgt
//
LOCUS       DAZKNV010000079         9613 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000079 DAZKNV010000000
VERSION     DAZKNV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.080"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(507..1049)
                     /locus_tag="ACG8M1_002451"
     CDS             complement(507..1049)
                     /locus_tag="ACG8M1_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HFQ0423116.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
     gene            complement(1362..1913)
                     /locus_tag="ACG8M1_002452"
     CDS             complement(1362..1913)
                     /locus_tag="ACG8M1_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0423117.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            2230..2628
                     /gene="merR"
                     /locus_tag="ACG8M1_002453"
     CDS             2230..2628
                     /gene="merR"
                     /locus_tag="ACG8M1_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFQ0423118.1"
                     /translation="MAYFISSFSEKCGVNKESIRYYERKNLLPEPDRTNSGYRVYSEE
                     DVKRVKFIKHLQEIGFSLNEIYKLLGVVDKDNIRCEGMFEFVSKKEREIQKKIENLNR
                     IEYMLKDLRARCPDEKELYACPIIEVLIEN"
     gene            2642..4282
                     /gene="merA"
                     /locus_tag="ACG8M1_002454"
     CDS             2642..4282
                     /gene="merA"
                     /locus_tag="ACG8M1_002454"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFQ0423119.1"
                     /translation="MNQFRMRIQGMTCTGCEKHIEKALESMGALNAKADFSQSEAVFQ
                     LPDDYAIENAIEAVKKINYQPEEVEKLPVQKRVMTNNKEDYDLLIIGSGGAAFSAAIK
                     AVEYGSKVGMIERGTVGGTCVNIGCIPSKTLLRAGEINQSAHVNIFEGLHTSTGEVEL
                     DRLVDQKNELVDDLRKQKYTNLIDDYGFDLIKGEAKFIDENTVTVSGQTYSAQRFLIA
                     TGASPLLPRITGLKEVDYLTSTTLLELRKVPKRLTIIGSGYIGRELGQLFHNLGSEVT
                     LIQRSKRLLKEYDPEISEAMEKALIEQGIKLISGATYERVEQDGNIKKVHIIVNGKNK
                     VIESDELLVGTGRKPNTEVLNLSAAGVQVGPNNEIKINAFAQTSNRKIYAAGDVTLGP
                     QFVYVAAYEGGIAAGNAIGGLNKAIDLSVVPGVSFTSPQFATVGLTQQQAKEKGYEVK
                     KAVLSLENVPRAIVNHNTTGVFKLVVDRKTQKILGVHIVSENAGEVIYGASLAVKFGL
                     TVADLKDTLAPYLTMSEGLKLAALAFDKDISKLSCCAG"
     gene            complement(4807..5292)
                     /gene="vanZ-A"
                     /locus_tag="ACG8M1_002455"
     CDS             complement(4807..5292)
                     /gene="vanZ-A"
                     /locus_tag="ACG8M1_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFQ0423120.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5445..6356)
                     /locus_tag="ACG8M1_002456"
     CDS             complement(5445..6356)
                     /locus_tag="ACG8M1_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFQ0423121.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            6510..6662
                     /locus_tag="ACG8M1_002457"
                     /pseudo
     CDS             6510..6662
                     /locus_tag="ACG8M1_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            complement(6782..7390)
                     /locus_tag="ACG8M1_002458"
     CDS             complement(6782..7390)
                     /locus_tag="ACG8M1_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFQ0423122.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(7396..8427)
                     /gene="vanA"
                     /locus_tag="ACG8M1_002459"
     CDS             complement(7396..8427)
                     /gene="vanA"
                     /locus_tag="ACG8M1_002459"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFQ0423123.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(8420..9388)
                     /locus_tag="ACG8M1_002460"
     CDS             complement(8420..9388)
                     /locus_tag="ACG8M1_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFQ0423124.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2970 a         1895 c         1752 g         2996 t
ORIGIN      
        1 attcctcctg gtatgttttc ttctagtcta cacaccttaa tttttctgtc tagttaattg
       61 tagcctatcc aacttaagat taatgacact aaattaacag actatacgta gtatctattt
      121 gctatgacca tatcttatat ccataagtca actcagccgg actaaaaggg ctaatcttac
      181 tagaacacaa gctgcacttg atatgcaaat taaccctgaa tcggaaaggt gcttaaattg
      241 gatattaacg gagggataaa gtaaaattta tctctaggga atgtttagaa aggatccaag
      301 ttccttaaca agtgacaatt agtaatgtag taacaacgat agattgtatg ccgaacattt
      361 caatttgata cgtataaaag acgatttcaa gctcatccgt gataaataac ccacatgaat
      421 gatttgaaat cgtcttaaaa tgctttattt tataacccaa aatagaataa ttacttcaaa
      481 atgacgtcgc atatcactat taatgattaa tcgatgactt ccataatcat tttaagttcc
      541 ccggatgtta aatcctcgct aaaaatgcca gtaacttttt gtccaggtcc aatttccttt
      601 gatgataggt ttaacaaaga gatagggata tagattaatc cgttttgttt caaagacaga
      661 gccaatattt ttttccttgt tcgaatagct gcatcatagc gaagagaaga gtaaacacct
      721 ctgccaacaa tagaaatatg cttccccaat aataaatcaa ggctacctat tacttgtaat
      781 ttctgaaagg tcgtcccatc cgttttgatt tgaatatcct gtaaatttat tttcctgtct
      841 aaggcatctt gaaaaaacaa gtgtgtgcct ctgcgataat caatgccaca gaggtgcata
      901 aaattagttg tcgaaaaaat aatcgctacc gttgagactt ctccgacaaa ggatactttt
      961 ttatctacaa aatgttcttg taagagatga gcagccttat aaatcgcgtt taactgtctg
     1021 gtaatttggg ttgtctcttt tatagacatg cgtttgtatt ctttttttgc cgcgtgcgaa
     1081 gaatgctcct ttttcccaat aaaaaaagct gctcaaaaga gcagcctttt gtacaggttt
     1141 agttttggtg cttgccaccc gccggaccct tacgttccgg atttgtatcg agtttagttt
     1201 tggtgctcgc cacccgccgg acccttatgt tccggattta tatcaagttg actatgagcc
     1261 tgctctcatt tgtatatata atataccaaa aaaaggttga tttgtccaat actgtgggtg
     1321 attataaccg tcttactgtg cttatctatt atataataca atcaaaaacc taaccgaaaa
     1381 tttaataacg tttcactgat ttcatcttca ttaattccga tgtagcgttt ggtaatcttc
     1441 tcgctgctgt gaccaaagat ttccattaag gtggccacgt ctttggtttt cttgtaatag
     1501 tggtaaccaa aggtttttcg tagggtgtgg gtgccgatat cgtcccttcc taacagcttc
     1561 gcgacctttt gaaacatctg gtagaccgta ttgacttcta aatggccgcc cttagtactg
     1621 ggaaacaagt aagcctccgg atctaagggt gcggtatagc cgtgaatcaa gtcctgtaag
     1681 ctgcttaagt ataaaatgcg tgtttttcct gtcttttgct ccacgatgcg cgggtttttt
     1741 gaggtaatca cgtctttttt cttgagttta acgatgtcgg acatgcgcag accgctgtta
     1801 attccaatta gaaacaagaa aacgtcacgt tccgcatttt tattccgtcg caggcaaaat
     1861 aaaaaatcat taatctcctg ttgcgaccgt agtggctgaa cattatagcc catgacaatc
     1921 cctccttttt agtctgttcg aatacatgat tatagttatt acaacacgaa atcgtgtgtt
     1981 tagggggagt aaaaaaaaag aaccctataa ggataggatt cttgatacat gattttatgt
     2041 aatttcatgt atttaggtcc gatattattt attataaaag aagtctcaaa atttattggt
     2101 accacattta attttcactt catttttgaa agtaaataag aaggaaaatg atattccccc
     2161 cttcgtatta tttttggttg gacatgtacc taagtacatg gtttataatt aaaaaaagga
     2221 tgtgatagca tggcttattt tattagctcc ttctctgaaa aatgtggtgt aaataaggaa
     2281 tccattcgat attacgaacg aaaaaactta ctaccagaac ccgatcggac taattccggt
     2341 tatcgagttt attcagagga agatgtaaaa cgagtaaaat tcattaaaca cctacaagaa
     2401 attggctttt ctttaaatga aatttataaa ttacttggtg ttgtagataa agacaacatt
     2461 cgttgtgaag gtatgtttga atttgtctct aagaaagaaa gagaaattca aaaaaaaatc
     2521 gagaatttga atagaataga atatatgcta aaagatttac gagcaagatg tccagatgaa
     2581 aaagaactat acgcgtgtcc tatcatagaa gtattaatag aaaattaacg ggggtaggaa
     2641 aatgaatcaa tttagaatgc gcattcaagg aatgacctgt actggctgtg aaaaacatat
     2701 agaaaaagcg cttgagagca tgggagctct caacgctaaa gcagatttca gtcaaagcga
     2761 agcggtattt caattaccag acgactatgc aatagaaaac gcgatagaag cagttaaaaa
     2821 aataaattat cagcccgaag aagtagaaaa gttacctgtt caaaaacgcg tgatgactaa
     2881 taacaaggaa gattatgatt tgctcattat cggttctggt ggagcagctt tttcagcagc
     2941 tataaaagca gtcgagtatg gatcaaaggt gggcatgatt gaacgcggaa ctgtaggcgg
     3001 aacctgtgtg aacattggtt gtatcccttc aaaaacgctg cttcgagctg gagaaatcaa
     3061 tcaatcagca catgtaaata tttttgaagg attgcacact tctacgggag aagtagaatt
     3121 agaccgctta gtcgatcaaa aaaatgaact agttgatgat ttacgcaaac aaaaatacac
     3181 taatttaatt gacgactatg gttttgattt aattaaagga gaagcaaaat tcattgacga
     3241 aaacactgtg acagttagtg ggcaaacata ttctgcccaa cggtttttaa tcgcaacggg
     3301 tgcttctcca ctcttacctc gtattactgg acttaaagaa gtagattatt taactagcac
     3361 aaccctcctt gaactaagaa aagtaccaaa acgattaaca attattggat cgggttatat
     3421 tggaagagaa ctgggacagc tcttccacaa tctgggttct gaggttaccc ttattcaaag
     3481 aagcaaacga cttttaaaag agtatgatcc agagatttct gaagcaatgg agaaagcttt
     3541 aatcgaacaa ggaataaagc tcatttccgg agcaacttat gaacgagtag agcaagacgg
     3601 aaatattaaa aaagttcata ttattgtaaa cggcaaaaat aaggtcattg agtcagacga
     3661 gctactagtt ggaacaggaa gaaaaccgaa tacagaagta ttgaacttga gcgcagcagg
     3721 cgttcaagtt gggccaaaca atgaaatcaa gataaatgct tttgctcaga caagtaatag
     3781 aaaaatttat gcagcaggag acgtgacatt aggacctcag tttgtctatg tagcagccta
     3841 tgaaggagga attgcagcag gaaatgcaat tggtgggtta aataaagcaa tcgatttatc
     3901 ggtagttcct ggagtatcat ttaccagtcc gcaatttgca actgttgggt taacacaaca
     3961 acaagcgaaa gaaaaaggat acgaagtaaa aaaagcggta ttgtcattag aaaatgttcc
     4021 tagagcgatt gtcaatcata atacgacagg ggtgtttaaa cttgtggttg atagaaaaac
     4081 acagaagatt ttgggagttc atatcgtttc tgaaaatgca ggagaagtta tttatggagc
     4141 atccttagcc gttaaatttg gattgaccgt agctgattta aaagatactt tagcgcctta
     4201 tctaacaatg tcagaaggct taaagttagc agctctagcc tttgataaag atatttcgaa
     4261 attatcttgt tgtgcaggtt aatatttcta tttagtttct tgtagtagct ggtaacacct
     4321 tggtttatct ttcgttatta tctataacga taggagttga agattatgac atcagcaaac
     4381 gtctacgtgc caattaatag ctctattcta gtggaggttg aagaaataaa agactattta
     4441 gaaacgcaat tgctcattta ggcaacgcag caagatatta ttgaagatgc gattgttgcc
     4501 ttacgtgctt aatatagata attaaatcgt atcaaaaaag gattctaccg cttaaagggg
     4561 taccgtcagg aaaatgcgga tttacaacgt taaggaaatt tattaaagag accaattcct
     4621 cagcactaaa attgataatt gggctttctt tgttactata gtgttaggta agctttttac
     4681 tttatcaccg gttttcccct cacttcacac ctacgggcga gtttccccac atcccgtttt
     4741 ccatctaatc caattcattc aatatcttta tgtgtatgaa agatcagatt gcttgattta
     4801 gacatcttac acgtaattta ttcttaaatg ggtacggtaa acgagcaata atacgagcaa
     4861 aagtatacct acaaaaataa taactctgtc taattttttt tgattcatat gcttattgct
     4921 taaaccatat aatttcagtc caagaaagcc tccaacagta tttgtaatta catctgttat
     4981 gtctgtcgct ccaatagcga agataaattg aattatttca aaagtaagac ttaaaaccag
     5041 tacaaaagca aacttaggta aaaatccgat ttctttaaaa ttgacattca aaagcaagcc
     5101 aaatggaata aagattataa cattatctat catctctctg aaattcccag tagcagtaaa
     5161 tggagtcaag ttaagacttc tttgatgata attaaatact gataaaatat tgtattgtaa
     5221 tttgaataac actaaccaga ttagtgtcac taaatataaa gctagcaatc ctctagataa
     5281 tatttttccc aatataattt cctctaattc ttttgtttaa gttgtatcat tagtatagca
     5341 atgtcctagt taacgtgggt tttaaattaa aaagctaacg ttaccccaaa agtgctagta
     5401 caataatgct gttcattaat ttcgttggtt tcattccgcc atccttacct ccttgaatta
     5461 gtatgtgttg atccgggaaa cactgtcaca attacaccgt ctatattgtt tcctgatatc
     5521 tcataacgaa gattagtcgg cacatgaatg gtggtatttt tagtaacagg ataataaaag
     5581 atctcatatt tttccccatt tacactaaca gaaatggttt tttcttcttt taggtaatcc
     5641 atatattcct cgagaacgaa attcttttct ttcataatcg cactatgtgg taaaccaaca
     5701 tagcgaatat gccatggttc atattgaatt cctgttaact ctgttttgtc ctctggataa
     5761 cgtaaaatga acccgtattt ccaagcattt tcttctatcc actttccttc aggggctcgt
     5821 tccattttcg tcaagcttga tcctacatct agtgataaac ctgaattatg ctcactataa
     5881 cctgctggta aggcatactc agcccccatt tcttggtaaa gcacactttg ctcatcaaag
     5941 tctcgatagc cactattaat aataaaatga ctaacgccac cctttacagc atcattgacc
     6001 atctctgaaa atttttgtgc tatttctttt gacatataaa tattactatc aagcaacccg
     6061 tatccattta ttaattcgtc atgtttagat aaattcacga tatctgactt cacactttct
     6121 tggcgaacag gatatttact attgattaat agcagatttc cttgataaac ctgttcttct
     6181 gtaattgttt tctcttgggt attttcagaa gtcccactat tttctaaatg ttctttggga
     6241 ttttgatcat aattttgaaa ttcgactttt tcctgagaaa acagtgcttc attaacgtag
     6301 tcataaccta agtatattaa gaataacaat aacaataaaa aaaacaactt cttcattttc
     6361 agtctcctcc ttaactatat agttggaagt atgaaatatt tctagaatct tccccttaaa
     6421 cggcacaatc tcgtttgaga ttgtgccgtt ttgccccgta aattacagtc aattatttcg
     6481 ccctactgga tttactatta tcaccaattt ccttagaaaa attaggttgt caaaatttca
     6541 actcacgttc tgttaaaggg ctagagagta gatttgaaag catattactg gcttacagtg
     6601 ttctattaag tcgagcacaa cgacgttttg aaggaacttt gagatattct ttaggatatt
     6661 aaaattaact agcaccacgg gttatctact atatataaat tccctaagaa ccagttacat
     6721 acgtcgggtt tcctgccgaa agagttagct tatatagttt gtccgtgcaa cggttaaaag
     6781 tttatttaac ggggaaatca aaatagctat tggggtatgg ttcgtctctt aatacatagt
     6841 gccaccattc gaggctatat gcttcaaacc cactgttttc catgatggag cgcaaacgtc
     6901 tgcgattttg cgcttcattg catgatattc catttgccgc atgatgagag cgttcatcca
     6961 taaaatcaaa tcggctcccc attggtacaa gctcacccgt gtctaatcga taaagcgtaa
     7021 gatcaatggc actgccgcgg ctatggcttg attttgaagc cacgtatcct tttgaaatca
     7081 tctcagttcg gtcaatattg ggataataac tttcctttgt caggttattt tccggctgtg
     7141 cagcccattg cataaaacag tttacagcac gcttaggacg gtaaccgtcc catagaagca
     7201 atccgtaccc ttgggtagca gccagttctt ttgccttcaa aagcgattca gccaactcgt
     7261 atgtccctac aatgcgattt acttcataac cgtcaaccgg ttttccggtg aaattatccc
     7321 aagtggcata tttagcgtcc caacgaacac cgtgtactat ttcatctaaa aaagtaaatc
     7381 ctatttccat gcttatcacc cctttaacgc taatacgatc aagcggtcaa tcagttcggg
     7441 aagtgcaata cctgcagcgg ccatcatacg gggataacga ctgtatgacg tgaaaccggg
     7501 cagagtattg acttcgttca gtacaatgcg gccgttatct tgtaaaaaca tatccacacg
     7561 ggctagacct ctacagccga gcgctttata tatttttttt gccgtttcct gtatccgtcc
     7621 tcgctcctct gctgaaaggt ctgcgggaac ggttataact gcgttttcag agcctttttc
     7681 cggctcgact tcctgatgaa tacgaaagat tccgtactgc agcctgattt ggtccacctc
     7741 gccaacaact aacgcggcac tgtttcccaa taccgcacaa ccgacctcac agcccgaaac
     7801 agcctgctca attaagattt tgctgtcata ttgtcttgcc gattcaattg cgtagtccaa
     7861 ttcgtccgcg ctattgactt ttttcacacc gaaggatgag cctgaacgcg ccggcttaac
     7921 aaaaacagga taggtaaacg tagctgccac cggcctatca tctttattaa taacccaaaa
     7981 ggcgggagta gctatcccag catttttcgc aacgatgtat gtcaacgatt tgtccataca
     8041 aattgctgag ctttgaatat cgcagcctac aaaagggata ccggacaatt caaacagacc
     8101 ttgtatggat ccatcttcac ctgacttgcc atgcaaagct gaaaatgcta catcaacatg
     8161 gttgatttca tattcatggt tctttttaac aagtaatccg tgcatttttt tatccggcga
     8221 gagtacagct gaatagcaat tgtcgttttc ccattccgcg caaggttttt cgcacatttt
     8281 ccatacacca gatttcgtaa ttccaatgta taacggctcg tatttttctt tattaatgtt
     8341 agcggctatc tctattgcag attttaccga tacgtcatgc tcctctgagc aacccccaaa
     8401 cagtattgca acttttattc tattcatgct cctgtctcct ttcaaaatcc aaacagtttt
     8461 taatggtttt ttcaacggta tcacgcaacg cttgctcggt ataataggcc gtatgcggtg
     8521 tgattatcac gttaggcatt ctttgaagtt taagtaaaaa ttgattatca attggttttt
     8581 gggtgcaatc agagtagaaa aactcttcct ctccttccaa tacatccaat gcggcaccgc
     8641 ccagtttccc gttttctaat gctttaacca actcataggt atctacaagt ggaccgcgcc
     8701 cagtattgat aagaaatgct ccttgcttca ttctctgtat ttgttcgtgg ctgataatat
     8761 agtgcgtatc cgtattgagc ggcacatgaa gcgtaacgat atcgctattt tgcagcaact
     8821 catcaaacgg tacatagttt acctctatac ttcggctgcg actataagcc aacactttac
     8881 atccaaatcc tcgcagccgc tcaataaccg ctttgcctat ctggcccgtt cccaccacac
     8941 caactgtcat gtcgctgagt accttgccac ggtcgctgtc caacctgaaa tcatgttttt
     9001 ccacagagcg cacaatcgat tttacgttgc gtactgccat aagaattagc atcatagtat
     9061 aatcggcaac gctatccggc gagtacgcca cattgtcgac agtgatgccc attctcttag
     9121 cagcagttgt atctatatga ttgcagccga tgcttcgggt agaaatatat ttcacaccgg
     9181 ctctcttcag cgcaagaaga atagaggcgg aaatctctga tttatgtccc acactgatac
     9241 attgattgaa aggcgcggat ttggcgttgg attccgacac gttggcgtta attatcgttg
     9301 ccataacgcc aaagcgaggc gaaagagcat ggaatgcatc tgcctcatcc tgctcacatc
     9361 cataaacagt aatgccgatg ttattcataa ttaagaccaa ccctttctgt gaaaggcacc
     9421 aaataaaacg gggatgccaa tggtaatctt gtcaaatctt tctctgaaga acgaaaacgg
     9481 ctcgttctta cggtattaag tctaccgtgt aagaacgagc cgtttcttaa tattaaattg
     9541 ttaatttcct aagaaaaagt aaagataacc ttgagatttt cctaaaaaat tatatacatc
     9601 tcttaggacc tcc
//
LOCUS       DAZKNV010000080         9470 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000080 DAZKNV010000000
VERSION     DAZKNV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.081"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(37..705)
                     /locus_tag="ACG8M1_002461"
     CDS             complement(37..705)
                     /locus_tag="ACG8M1_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0423125.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            839..1126
                     /locus_tag="ACG8M1_002462"
     CDS             839..1126
                     /locus_tag="ACG8M1_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423126.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1542..3080
                     /locus_tag="ACG8M1_002463"
     CDS             1542..3080
                     /locus_tag="ACG8M1_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFQ0423127.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3077..4042
                     /locus_tag="ACG8M1_002464"
     CDS             3077..4042
                     /locus_tag="ACG8M1_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0423128.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4029..5351
                     /locus_tag="ACG8M1_002465"
     CDS             4029..5351
                     /locus_tag="ACG8M1_002465"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0423129.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5414..5518
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5592..6335
                     /locus_tag="ACG8M1_002466"
     CDS             5592..6335
                     /locus_tag="ACG8M1_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0423130.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6350..7342
                     /locus_tag="ACG8M1_002467"
     CDS             6350..7342
                     /locus_tag="ACG8M1_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0423131.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVNYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7354..8091
                     /locus_tag="ACG8M1_002468"
     CDS             7354..8091
                     /locus_tag="ACG8M1_002468"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0423132.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8081..8803
                     /locus_tag="ACG8M1_002469"
     CDS             8081..8803
                     /locus_tag="ACG8M1_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFQ0423133.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8887..>9470)
                     /locus_tag="ACG8M1_002470"
     CDS             complement(8887..>9470)
                     /locus_tag="ACG8M1_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0423134.1"
                     /translation="AGAAFFMGTTAHADEAYTVQSGDTLSTISQKYVGDNSLINAIAE
                     SNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEKQAAP
                     VAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYLNGDY
                     SAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3099 a         1634 c         2003 g         2734 t
ORIGIN      
        1 tttctgtaaa ttaaataaag tagtgaaaaa taagaatcag tgctctaact gttcaagagg
       61 atcaagtggt tcaaatgttt ctgtagtctg ttttgcttcc aattggggca aaacagatcc
      121 aatttccaga tacttcactt tattcaatgt ataagataga atagaacagc taagtaatgt
      181 atacagaaaa tgtgtgagat ccaaataaag caaggagaca actaaaatac caaaagtaat
      241 caagaaaaga cttttgccaa tcttaatatg aaaatatttt tcaatggctt gataaatgat
      301 atctgttccg cctgtgcttc cgccgaatcg aaagacgaga ccgcaaccaa tgccagaaag
      361 aatacctgtc atcaaactat tgatcagtag actatctaca gcaaaatgta tatgaaggct
      421 ctcccataaa tgtaaaaaga aaactagcgc aaatgttccg acgatcgtcc ggagaaaagc
      481 gtgttttcca aaaagaaaca atgagataag caataaaggt aaattaaaaa gcagtgaagt
      541 gacagaagga gcgaatccaa aaagattatg caaaagcaaa gcaataccag taaccccacc
      601 atctgccagc ttagatggaa tattgattcc tgtcacagct aatccgtaga ttcctgcgcc
      661 taaaatgatt ccgcacaatt ctgtaaataa atttaatttt ttcatttcta gcctcttttc
      721 ttttgaaaat tttcagcaac ttctttatta tactgactta tactcttact tcaagaggaa
      781 aatgaaaaaa aattattttt ggctgtttct ttttatttat caaataagga gtggaaaaat
      841 gcgagcagca gacttattga caattcttac aaaatcaccc aaaaaaacag agtatcaagg
      901 agtttttttg gctcaagaac aaaaactggt gcctgtgaca atggtccaga taaataaagc
      961 aaatcaattt atctttttat ttgaacacgg caaagcacca cttgctatga aagacatctt
     1021 tctttttttg atgaagaacc gtgagaaagc tgtttattat cagtcaaaag aagaactcat
     1081 tcctctttat ggagtgaaag agatagaaaa taaagtggtg atataagtaa aaataagaaa
     1141 acaagacgtt tatgatgtca aaacaaccat tttttacatt tttggcaaaa aagtgtcatg
     1201 atacagtata atattcgttg aacaggccaa taaaggtgtt ctcccccacg agatttctac
     1261 tttattggct gtttcttttt attaaaataa aagttgtgtg tgtaaaaaag atatagctga
     1321 ttccaagtga caatttcgta tagattttta tggtattcgt agtgaaaaaa cgagaaccaa
     1381 aaagttgatc cgactttgtt gcttggattc tttttttgtc agcatattta gaggtatttt
     1441 tttctttttt ttgttcgtgc tgtaaggtta aggcaagaca agttagttgg gaaaaaggaa
     1501 agaaatgttt atacttaaag aataacagaa aggaaggtcg catgaataat tttatacaaa
     1561 cattaagtga aagaaaaggc gagttgctgg aagctgcatt tcaacatctg tccatttctc
     1621 tcatttcttt gctgattgca gcactgattg ctattccttt agcgatttgg gcagccaatc
     1681 ataaaaaaat ggcagaagtc ttattgcaga tcacgggtgt gctccaaacg attccttcac
     1741 ttgccttatt aggtttactt atcccatttg tagggatcgg aactgttcca gcattgattg
     1801 cacttgttat ttacgctttg cttccgattt tccaaaacac gtatattggt ctagctgaaa
     1861 ttgacccgtc tattgaagaa gcagcggtag catttggtat gtccagaatg agacgcttgc
     1921 tgaaagtaga gcttcccatc gcattacctg tcattatctc aggtatccga actgccttag
     1981 ttttaatcat cggtacggct actttggcag cattgatcgg agcaggtgga ttagggacat
     2041 ttattttgtt aggtattgac cgaaatacac ctgttttgac attgattggt gcgatcagtt
     2101 ctgccttgct tgcaattata ttcagcggac tgattcgctg gttgcagcat aagaaacctc
     2161 gatattccat cattacttta gcagcagtgg tgtgtttatt tggcggcgtt tctttatatc
     2221 agtctgcctt gtttaaaaat gaaaccatca cgattgctgg aaaattagga gcggaacctg
     2281 aaatcctgat ccaaatgtat aaagaattga ttgaagacaa cacaaaaaca gaagttgaat
     2341 taaaaccgaa ttttggcaag acgagttttt tgttcaatgc actggatcaa ggtcaaatcg
     2401 atatctatcc tgagttcaca ggtactgtcc tagaaagctt ggtgaaggta cctgaagcaa
     2461 tgaaaagtgc tgatttgaca aaagaaaaaa catatgacga agcagaagaa ttattgaata
     2521 agcaattcga tatgacatta ttaaaaccaa tggcttacca aaatacgtat gccttggcag
     2581 tcaagagatc ttttgcgaac gaacatcaac ttaaaaagat ttccgatttg gcagctatct
     2641 ctgatcagat caaagcggga ttcacactgg aatttattga tcgttcagat ggatataaag
     2701 gaatccaaga agcatatggc ttgaattttt caagtgtaca aagcatggag ccaagtttgc
     2761 gttaccaagc aatcaataat ggagatgtca atattgtgga tgcctattcc acagatagcc
     2821 agctcaagga gtacgatcta gtgactctag aagatgatcg agggttattc ccagcttatc
     2881 aaggcgcacc gctgatgaaa aaagattttg ctaaagaaca tcctgaaatc gttaaagcac
     2941 tgaataaatt aagcggaaaa ataacagagg atcaaatgat tgatatgaat taccaagtca
     3001 atgtcgaaaa gaaaaagccg acagaagtag cacgaatctt cctgaaaaat gaaggattag
     3061 taaaggagga agatcagtga ctaaattaat cgagttcaaa catgtgcaaa aaaagtatga
     3121 tggaaagtat gtcatcgatg acctaaatct ggcaatcaaa aaaggagaaa tctttgtttt
     3181 ggttggtcct tccggtagtg gaaaaacaac tactttgaaa atgatcaatg gattatctaa
     3241 accatcagca ggagacatct acttcaaagg aaaatcgtta aatgaatata atctgcagaa
     3301 aatgcggtgg aatatgggat atgtgctgca gcaaatcgct ttgttcccga ccatgacagt
     3361 caagcaaaat attgaagtca tccctgaaat gttaggttgg gaaaagcaga aaagagcaga
     3421 ccgtgtagat gaacttcttc aaaaagttgg cttatctcct gatatttatc gagatcgtat
     3481 gcctagagag ttgtctggag gagaacagca acggatcggg atcatccgag ctattgctgc
     3541 aagcccagat gtgattttga tggacgagcc atttagcgca ttagatccga tttcaagaaa
     3601 ctcattacaa gaattggttt tgtccttaca cgaagaattg ggcacgacca tcgttttcgt
     3661 tacgcacaat atggaagaag caatcaagct aggtgatcgt attgcattta tgaaggatgg
     3721 agaaattatc caatgtgaca caccagagca gttattgatg aatcctaaaa acgactacgt
     3781 tcggcatttc tttgatgaac cgaaacagac gaaagagtgg cgagtagaag atttagtcgt
     3841 caatggatat ttcttaaatg aaataccaga aaatgctcgt caacaagttt gctttgatac
     3901 gcctatgaaa gaagtatatt cgcttctttc ggtgtatcca agcattgtga tagtagaaaa
     3961 gcaaagaagt attgggtcgc tgacaagtaa agaaatcttt gcttttttaa gtcgagagga
     4021 ggaaggaaat gaaaacatat gatgcaatca tcatcggttc aggtgtgagc ggcttaagtg
     4081 ctgcttatgg attgaaagaa gcaggtaaaa cagtactagt ggtcgaagaa gatctatggg
     4141 gcgggacttg tcctaaccgt ggatgtgatc ctaaaaaagt cttgttaagt gcagtagagg
     4201 cacgtaatcg ggtaaaacaa ttgagtggaa aaggttttaa cgagatccca actgccaact
     4261 gggaagaact tcaaaaattc aaacgaacat ttacggatcc agtcccagaa agccgaaaaa
     4321 aacaattagc agaagctgaa atcgatcatc tttcaggaac cgctcgtttt ttggatgatt
     4381 catctattga agtcaacgaa gaagtcttcc atgcggatta cttagttttg gcaaccgggc
     4441 aaagacctac gatcttacca gtggagggaa aggaatactt gaaaactagt gcagactttt
     4501 tatcattgcc tgtactgcct aaagaaatca tttttatcgg tggtggttat attgcttttg
     4561 agctagctac gattgccaat gctgcaggga gcaaagtaac cattgtccat cataatcaac
     4621 ggccattaaa agaatttgag gcgtctttgg tagaggaagc cgtccatcaa atggaagcat
     4681 ctggcattca gtttgctttt ggtgttgaaa cccaaaagat catttcagaa ggtactcgct
     4741 atcgtttagt cggaaaagag acggaattag tagcagatat gattttttgt gcgactggga
     4801 gacagccgaa tacagaatct ttagcacttg agcaagcgaa tatcgtcttt gataaacacg
     4861 gaattgcagt caatgattat ctgcaaacga gcaatccaaa aatttttgcg tgtggagata
     4921 ttgtttcaag gaaaacccca aaattgacac cagtcgccac ttttgaagga aattatgtag
     4981 ctaagcggat aacggatgca acaagcgaac ctatcaaata tccgattata cctacgatcg
     5041 tctacgccag tcctaaactt gctgaagtag gagttacaaa aagtcacgcc tcttcgtcag
     5101 atcaagtggt agagatggat cttaccagtt ggttcaccta tcatcgtgtc aatgaaccag
     5161 ttgctaaggc tgaattgacc tttgaccagc aaaattattt gattggtgct gcagtgatta
     5221 gcgagcaagc agacgaattg atcgatgatt tgacactcgt catcaatcaa aaattgacta
     5281 aaaaagagtt ggatagctat atcatggggt atccgacatt ggcaagtgat ctctcctatt
     5341 tattgaaata atcagcatga taactaaagc gcttgttgct ttttccttct tgtgctacac
     5401 tttaaaaaat gaatacctgt ttctggggat gtcgtagacg acatgagagt aagttgtgaa
     5461 cttagaccca ttgaacctgt cagttaatac tggtgaaggg agaaacatag cagacgcttg
     5521 aagcgggtta ctatgtcgtg cccatttcaa gcgttttttg ttattcatat tagaagaaag
     5581 gaggtaacaa aatgaagaaa aatctttatc cagcagtcag tatggcattc attttaatta
     5641 tttggcagat tgttgtcata gtttggaaaa tacctgcctt tattttaccc ggacctgctg
     5701 ctgtattttc tgcattagcg gcagatgcac aagtattact ttcccattct gtcacgacat
     5761 taaatgaagc agtgcttggt ttggtaatag ctagcgttct ttcttttatt actgccttgg
     5821 caatggatta ttggaagttt ttagaaatgt ctttttatcc gttactagtg atttcacaaa
     5881 tgttgccaat catggtgtta gggccattac ttaccctatg gtttggtttc ggtatgcttc
     5941 caaaagtgat ccttgttgtc ttgataagct attttccgat cgtagtttct ttttcggata
     6001 cattgaggaa agtatcaaaa gagcaaatca tctttttgaa aacgatgggg gcagatacag
     6061 ggaagattta tcgaatatat aaaataccag cgggtttatc cggcttcttt tccggtttaa
     6121 aagtggctgc tacttattgt gtcagcggag cagtcgttgg agaatggcta agcgctcaag
     6181 caggcttagg gtattacatg atacgcgtaa aaaacagcta ccagatcgat aaagtttttg
     6241 ctgcgatcat ttgtgtcatt ctattgagtt tattgctgaa tggcgcttgt tcattattga
     6301 aaaaagggta ttatcgtatg ctttatattt tttaagagaa ggggatcaaa tgaaaaaatt
     6361 atggctttta ttaccgctac tgttgctttt atccgcttgt ggcactgcaa aagaaacaag
     6421 tagcaaacaa gaaataaagg atttgaaaaa agtgacactt gttttggatt atgtaccgaa
     6481 tactaatcat actggcatct acctagcaaa agaaaaaggc tattataaag aggctggttt
     6541 aaatgtccaa atcatcgaac caggagataa ttcgacaagt attggtctag taggtgcgga
     6601 caaagcacaa tttggtgtaa attatcaaga agatgtcact tatgctcacg cagatggaca
     6661 gaatatacca gtcaaagcaa ttgctacagt gatcaaacat aatacttctg gattcgccac
     6721 cctatcagac agtaacatcc attcaccaaa agattttgaa ggaaaaacat atgcaggttg
     6781 gcaaagtcca agtgaagaag ctgtcttaaa agctgtgatg gaaaaagacg gcggggactt
     6841 ttcaaaactg acaatggtag gaagcaatgg agaagggcca gaaagcttag gaaaatcctc
     6901 agatatccaa tggtactttg aaggttggga tatgatcaaa gcaaaagaag cgggtattga
     6961 actaaactat atcccattga aagaattaga tgaacggtta gattactata ctccggtaat
     7021 tattacgaat gatcaactga tcaaaagtga tccagaattg gtacagtctt ttatggatgc
     7081 cacgaaaaaa ggctatcagg aagctattaa ggatccaaat gacagtgcta aactgttgca
     7141 aaaatatgca aaagaaaatg atcggacgtt tttagaagaa tcacaagcat tcttgtcaaa
     7201 aaattatacg gatgatcctg agaattgggg attgatggaa gaaaaagttt ggcgcaatta
     7261 tacagctttt atgcaggaaa acggattgat caagcaagat gtaccttcgc aagaactatt
     7321 cactaatcag tttataaaat aggagtgata gatatgtcaa tccaaatcag ccacttgaat
     7381 gtagtcattg aaaacctgaa aatattagaa gacatccatt tcactatccc taaagatacc
     7441 tttacatcga ttgtcgcgcc aagcggagcc ggtaagtcaa cattgctgaa aactttaaca
     7501 ggagtccagc ctatgacttc tggaacgatc aaagtagacg atcaaaaagt aactggtctc
     7561 catacagcat ttagttatat gccgcaagaa gatatgttac ttccttggct gagcgtctat
     7621 caaaacgtta cgttatatca aaaaatcaat catctaacaa tcaatgaaga acaagtaagg
     7681 gattatctgg atatctttgg gttaaacggc tatgaacatt ttttgccgga acaattatct
     7741 ggcgggatga agcagcgaac ggccttgtta cgaacaatca tgaatccttc ttcttacttg
     7801 cttcttgatg aaccatttgg agcgttagat gctatgacca gagggcagat gcaagactgg
     7861 atgttgaagc tgcctaaaaa agcaaagcgg actactttac ttgtgacgca tgatatcgaa
     7921 gaagcaattt atttatcaga caggattctt gtgctttccg cccgtccggc acatgtgatt
     7981 gctgagattc aagtgcctga aaaacgacgg tcacgtgaat ggctactgca gcaatcagag
     8041 ttgaagcaaa cgatttatca gttattggca ggtgaattag atgttaagtg atgctcattg
     8101 tcatttagat gggagtcaga gtttagcact ccttcagcag gaacacacga ttttgacgat
     8161 catcaattgt gattcgccag aagaatggaa ggaaaacaga cagcttgcag caagtaagac
     8221 tcaagcctta agttacggta tccatccttg gaaagcagat agctatacgt ttgaacaagt
     8281 tgagcctttt ttgaaaaaag caaggatcat cggtgaaata gggttagata atatttggac
     8341 gaatgtaccg atgactacac aaaaaaaagt atttgagcga cagcttgctt ttgcagccat
     8401 aaatgagaaa cctgttgtac tgcacacaaa aggatgcgaa aaagagatct taaattatat
     8461 ccaagcttac cctaatcact atttgatcca ttggtattct tctttggact atcaacaaga
     8521 ctatattgat ttaggctgtt atttcagcat tggtcttgat ttgaaaaaga atccagcagt
     8581 ctggcaacta gctaaagcag tcccaatcga ccacttactt attgaaacgg atggactaca
     8641 tgcagcagag tgggctttag gggggatttt ttcagaaaaa gattatgtct cactgcttga
     8701 agaacagtta aagacaatcg ctgagatcaa agagctatca gttgaagaag ttaaaaaaaa
     8761 tacttatcaa aacttggaac gtttcattag attaggtaaa taaaaaagag atgtgacaca
     8821 actagtgtcg cacctctttt tggctttctt tgtataaaag taaactgttt gattaataaa
     8881 tgaatcttag taccaaccgt ttgcttccca gaatgctttc gccgcttccc aagaaccata
     8941 acgtgaagta acatattgtt ctgctactct ttcttggttt gcagcagagt agtcaccatt
     9001 taagtaagaa gaatctaatt ggtaacgtcc gatgtaacgt ccgttcgttg ctgtgtaaga
     9061 accgcttgat tctttttgtg cgatccattc ttttgcagag cttgtgcttg ctggagtagc
     9121 agcagtttct gttacagcag gagcaggttg tgtttcagca acaggcgctg cttgtttttc
     9181 cgtttgaacc gtttcttgta caacaggttg ttcagcttgg actggtgctt cttgaacggc
     9241 tgcttgaggt tcagcagctg cttgtgcaga gccttctgtt gggattgtta attgttgtcc
     9301 tgagtaaatc aggttaatat cagaaattga atttgattct gcaatggcat tgatcaagga
     9361 gttatcacca acgtattttt gagaaatcgt tgatagagta tcacctgatt gaacggtata
     9421 agcttcgtcc gcatgagcag tcgttcccat gaagaatgca gcgccggcag
//
LOCUS       DAZKNV010000081         9352 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000081 DAZKNV010000000
VERSION     DAZKNV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.082"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1101
                     /locus_tag="ACG8M1_002471"
     CDS             <1..1101
                     /locus_tag="ACG8M1_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0423135.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1615)
                     /locus_tag="ACG8M1_002472"
     CDS             complement(1280..1615)
                     /locus_tag="ACG8M1_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0423136.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1599..1862)
                     /locus_tag="ACG8M1_002473"
     CDS             complement(1599..1862)
                     /locus_tag="ACG8M1_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFQ0423137.1"
                     /translation="MAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQGKI
                     PFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="ACG8M1_002474"
     CDS             complement(2322..3125)
                     /locus_tag="ACG8M1_002474"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0423138.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="ACG8M1_002475"
     CDS             complement(3103..4227)
                     /locus_tag="ACG8M1_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0423139.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="ACG8M1_002476"
     CDS             complement(4243..5058)
                     /locus_tag="ACG8M1_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0423140.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5920)
                     /locus_tag="ACG8M1_002477"
     CDS             complement(5048..5920)
                     /locus_tag="ACG8M1_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013669610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0423141.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="ACG8M1_002478"
     CDS             complement(6005..7294)
                     /locus_tag="ACG8M1_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0423142.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7438..7950)
                     /locus_tag="ACG8M1_002479"
     CDS             complement(7438..7950)
                     /locus_tag="ACG8M1_002479"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423143.1"
                     /translation="MTINCDLKEEGLEMAVFSLAQTYQIWPQIVLSGYVQLSWAAIWG
                     KHIFYNIENQFEGKKLGDITEADLIDTLQKLAYQSVQIVNIHEGWLTKLAREVGQQLG
                     LTFSVWTVNELETIEYLARCGVYNITSRCAWAYLWKKGAQNKLFYNQNRGVKRFGDGI
                     HDHMGALFLA"
     gene            complement(8017..8160)
                     /locus_tag="ACG8M1_002480"
     CDS             complement(8017..8160)
                     /locus_tag="ACG8M1_002480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFQ0423144.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
     gene            complement(8643..>9352)
                     /locus_tag="ACG8M1_002481"
     CDS             complement(8643..>9352)
                     /locus_tag="ACG8M1_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFQ0423145.1"
                     /translation="LVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRP
                     KGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLNQC
                     TISKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMRWT
                     KYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSLE
                     QLLSTVWLSVRTAFFVG"
BASE COUNT         2880 a         1996 c         1492 g         2984 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacagccaga ctgtagacaa aagctgttcc
     8701 aaactcgtaa ctcgagcttg gaacagcttt ttatctactt cgtttcgaat ttttgaacaa
     8761 aaaaataaag gctccttgcc tttccatagc caggtggcta atttctttaa attcattgca
     8821 gcaaacacta gcatcgtatg cgtcgcgact ttttccaagc ctcgatactt ggtccaacgc
     8881 atcccatgct tttcttttgc atccgcaaat attcgttcaa tcgtttgttt ccgttttttg
     8941 taaattgatt tattcagatc tgttaggcga agatgttcca cttcatccat cagatctccc
     9001 caaacatgtc tcgtgatgac tcgttgatga tttttactta tggtacattg gtttagcaga
     9061 ggacagttca cacattcttt tggattggat ttgtattctc ggtacccttc tcgagtaacc
     9121 gttgaaaaag cgagcatttg atcttgcgga caaatataac aatcaaaata ctcgtcatag
     9181 agaaactcat tttttgataa tagccccttt ttccctttgg gccttgaata aggcaaacaa
     9241 ggtcgaaggt tcaaatgagt caaaaagtga acaaacttag gtgtcttata cccagcatca
     9301 gcgacaacac aattgatttc aggaaaaagt ctcttcgatt gtttgacgag ct
//
LOCUS       DAZKNV010000082         9297 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000082 DAZKNV010000000
VERSION     DAZKNV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.083"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..2198)
                     /locus_tag="ACG8M1_002482"
     CDS             complement(78..2198)
                     /locus_tag="ACG8M1_002482"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0423146.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="ACG8M1_002483"
     CDS             2428..3606
                     /locus_tag="ACG8M1_002483"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFQ0423147.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="ACG8M1_002484"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="ACG8M1_002484"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFQ0423148.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="ACG8M1_002485"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="ACG8M1_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFQ0423149.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="ACG8M1_002486"
     CDS             complement(4959..6212)
                     /locus_tag="ACG8M1_002486"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0423150.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="ACG8M1_002487"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="ACG8M1_002487"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFQ0423151.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="ACG8M1_002488"
     CDS             7789..9135
                     /locus_tag="ACG8M1_002488"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFQ0423152.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
BASE COUNT         2995 a         1680 c         1925 g         2697 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatc
//
LOCUS       DAZKNV010000083         9114 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000083 DAZKNV010000000
VERSION     DAZKNV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.084"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(57..350)
                     /locus_tag="ACG8M1_002489"
     CDS             complement(57..350)
                     /locus_tag="ACG8M1_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFQ0423153.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(378..1043)
                     /locus_tag="ACG8M1_002490"
     CDS             complement(378..1043)
                     /locus_tag="ACG8M1_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFQ0423154.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1183..1815)
                     /locus_tag="ACG8M1_002491"
     CDS             complement(1183..1815)
                     /locus_tag="ACG8M1_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0423155.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1822..2889)
                     /gene="liaS"
                     /locus_tag="ACG8M1_002492"
     CDS             complement(1822..2889)
                     /gene="liaS"
                     /locus_tag="ACG8M1_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFQ0423156.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(2886..3617)
                     /gene="liaF"
                     /locus_tag="ACG8M1_002493"
     CDS             complement(2886..3617)
                     /gene="liaF"
                     /locus_tag="ACG8M1_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFQ0423157.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAV
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(3785..4264)
                     /gene="greA"
                     /locus_tag="ACG8M1_002494"
     CDS             complement(3785..4264)
                     /gene="greA"
                     /locus_tag="ACG8M1_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFQ0423158.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="ACG8M1_002495"
     CDS             complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="ACG8M1_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFQ0423159.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            5740..6900
                     /locus_tag="ACG8M1_002496"
     CDS             5740..6900
                     /locus_tag="ACG8M1_002496"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0423160.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KELNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(6940..7887)
                     /locus_tag="ACG8M1_002497"
     CDS             complement(6940..7887)
                     /locus_tag="ACG8M1_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFQ0423161.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(7920..>9114)
                     /locus_tag="ACG8M1_002498"
     CDS             complement(7920..>9114)
                     /locus_tag="ACG8M1_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFQ0423162.1"
                     /translation="AYMVILVITSFVHKEYGLGENLKTIMWAILQYFLIYQFAFENSD
                     NKRFFKRISWGFIYSWFVLVSMSMVLFFGKFGYEKYYNARHRIRIGFLESRLFGTFSD
                     INNAAIASLVVIVLILFYLYNKKVTGLNKIIFLINLPLQFIYIVLSGSRSTYVVSIII
                     VAISSFIVVLKRNGTKKDLKNYILAIVSSIGSVLILFALFNATKILFQELLPHLKEIN
                     FFNFTERHKELMNNSQHINNTQTPDNTLVRKDVAENTDISNARITIWKSAWEIFKTSW
                     LIGVSPKNVVSYAQSIIPDGYIAKVGIAIHNAYLNVLTSTGILGIIPFMAFLIKSFVL
                     NVYRIIYNKCIGKDYHFVYCLVILSYALYAALNNELVYENTVGTFVFWLFLGRVNSKN
                     NSSYF"
BASE COUNT         2802 a         1864 c         1385 g         3063 t
ORIGIN      
        1 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
       61 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
      121 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atccatttcc
      181 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
      241 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
      301 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
      361 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
      421 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
      481 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
      541 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
      601 gaatatttat ctgacagctc taagtagtct agaatattct ttgatactaa gttatgtgca
      661 atccgtatcc ccatgtctcg ctcagggtgt acgacacgat ctgctccgat cttctctagt
      721 acacgggcat ggtactcatt ttgggctttt gctaaaatat tcggtacgcc catttccttt
      781 accatcagag taactaagat gctggcttgg atatcttctc caatagcgac aattacatga
      841 tcgaaatttc ttatacctaa tgaacgaagt gtcatctcat cctgtgcatt tgccacaaca
      901 gcatgggtgg ctatattcat atattcattg actcgatctt cattactgtc aatagccagt
      961 acttcttgtc cagcttcgat cagtgtacgg cagatgcttc cgccaaatcg tccaaggcct
     1021 acaattgcaa aattttgttt caccattttc ctcctttagt atcttctttt ctcagtataa
     1081 caaagccttt ccaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
     1141 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
     1201 tttaaacgca tagatagctg cttgagttcg gtcttctacc tctaacttag ctaatatatt
     1261 cgacacatgc gttttgactg ttttcagtgt gataaacaat tcatccgcga tttcctgatt
     1321 acttttccct tcagaaatca gcatcaaaat ttcattttct cgattcgtta attcttcatg
     1381 caatactgga tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttcaggttc
     1441 tagtactcgc tcgccgcgtt gcgtagccct tatagcatca gctatttcat gtgctgtaga
     1501 cgtcttcaac aaatatcctg ctgctcctgc ttcaattgca ggataaactt tttcatcatc
     1561 aataaaactt gtgacgataa tgattttggc ttttggccaa tcttttaaga ttgcttttgt
     1621 tgattcgatg ccatccattt cttccatgac tagatccatt aaaatgacat ccggtcgaag
     1681 tgccatcgcc ttttcatagc cttgacgtcc attttcagct tctccaatca cttcaatgtc
     1741 ttcttggata gataaataag aagagacgcc taagcgtacc atttcatggt catctactaa
     1801 taaaactttt atcatcttta tctatgcctc cttcatcaaa gggaccttgg tctccacgct
     1861 cgtaccttgc cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
     1921 tttgatattg ttcaatccat aacttcccgt tttggtttca ttcatattaa atcctgtccc
     1981 gtcgtcaatg atacgtaata aaagattgtt atctatttta tgcaaataga cttctaattc
     2041 attagcctta gcatgtctta atgtgtttga taacaattct tgaacgattc ggaacaagtg
     2101 atcctcaatg gaactagtta attttacatc ttctacctcc cattttagcg aaatctggat
     2161 tttattctgc aattccttca ataactgctc aatgccttgt tttaaacttt tttcttctaa
     2221 attgactgga cgcagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
     2281 ctctgccacc attttcaact gcttacggaa catttctggt gtctcacttt tttctgcttg
     2341 ctccgtcaat gccgacatca tcatcatcgc tgcaaataat tgctgtgaaa ctgaatcatg
     2401 aagctcacga gctaatcgat gcctttctaa ttttaaaatc tcttctttgg tttgtccatc
     2461 tacatattga ggacggctag tcataatctg taattcactg gatacttcga tcattttttc
     2521 ttttatttta gtaatttcca tatcaatatc tttgatgtac agatcatccg acgcgcttgg
     2581 gatcggctga tgcaaaagtt tggattcata attgccagaa gaaagtgcac gaagcttttc
     2641 ttcgattttc ccgtattttg ccttttgaat aagtgataac aatagaaata cgatcaatcc
     2701 tacacctaat gaaattgcca tcaaatggaa gataagcgga acgtataata aacgcgcacg
     2761 cagcaattct ccccaccaat gactttggtt actggcataa aaataagtga aaagtgaaaa
     2821 tagaataata aggaaagccg caatccccga ataaacagct agcattgctt tggatattct
     2881 tcccatcata ttcgtatcac ctcgacatct ccaaccaaag tattggtaat gatcttcaat
     2941 ctgcgaggat tttcatcata atcactgctg cagattttga tctgttcgtt ttttaaggaa
     3001 aactgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa acgaatagcc
     3061 actcccaggg gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
     3121 tcatcttttg gcaaaagtgt attgcccaaa tcgatgatag tatcaccaga aatgatggca
     3181 atgttgatat catcccattc atagacgtcg tttccaatac gttggttacc aaataattgc
     3241 tgtcttttac gctcattatt atgtgttttt aattgctctg tttggaccat catgatctgt
     3301 ttttttcgcc aaaaagcatt ttttgtcaaa tctattcctg aaatctctac acctttcagc
     3361 ccgataaata aaacggccaa tacaaccatc atccataaag caggactgtt gactaagcta
     3421 aaaaaaatga ccaagctccc taagatcaat tgaaaatttt gaaatttagt acgaggatat
     3481 ttgcgcacag ctagatatat attgaaaata ccgaatatta ctaaaagcaa aagtccagta
     3541 ttgtttacga tttgccaaac agcaaataac agcagcagtg cttcgactac cacaaaaaaa
     3601 cgccaagaac tattcatcgc tttttctccc tcctgacaca ttctcatttc atcataccta
     3661 tttttttgac tgttggctat aggactttag atgtaagatc gttcagtgaa acctgcaata
     3721 ctcaaagaga aaagatctag agtgcgtcat cagtaagatg aactctctag atctttcagt
     3781 cagactacgc ttgttctact ttgacgattt taactaacat atcgccacct ggtgtagcaa
     3841 tggttacttc atcattttta cgtttgccaa tcaatgcttg cgcgatagga gaatcattgg
     3901 aaatctttcc agaaaacggg tctgcttcag cacttccgac aatcgtgtac tcttcttcat
     3961 ctccatcagg caactcgatg aacgtaactg ttttaccgat cgatacctca tctgcatcta
     4021 cgccgtcatt atcgatgatt tgtgcaaaac ggatcatatt ttcaattgtt gtgattcttc
     4081 cttcaacaaa tgcttgttca tctttagctg attcgtattc ggagttttcg gaaagatctc
     4141 cgaaaccgcg agcgattttg attcgttcaa tgatttctcc gcgtttaact gtttttagtt
     4201 cttctaattc tttttctaat ttttctttac cttctagagt cattggataa actttctcta
     4261 ccatgtgtaa cgtctccttt tttcgataaa ataccgcaaa aggtaatctt ttgaggaata
     4321 tagtccaaaa aagattacca cgcttttctt aaaatgtaaa tgtttttcta aaaatgatca
     4381 atgactagcc cctgtttttc taagaattat ttacatattt ttgcactagt tccatatgtt
     4441 cttcatacgt tttagcgaaa taaacatttc cagtgctcgt atctgctacg aaataataat
     4501 agtcattttc tgctggttct aatactgcct tgattgcctc ttcgcttgga ttgtcaaaag
     4561 gaccaggccc atagccggta ttggtataca aattgtatgg tgaatctaca gctgtatctt
     4621 catacgtcac caattcttta tgttctccta atgcatataa aacagagata tctgactgaa
     4681 gtggcatatt tgccttgatt cggttaaaga agacttgtgc aatattttta cgatcatttt
     4741 cttttacgcc ttctttttca actagagaag ccaaagttaa aacttcttgt acagtcaaat
     4801 ttttctgttt gatagctgaa taatagtttt gcatgaccgt atttgttttg ttcaccatct
     4861 caatcacaag atccttaagc gaagtactcg tgtagtaatc ataagtagct gggaataagt
     4921 agccttccaa acggtatttt gtgttctcag ctttagaggc actttccaac aattctggga
     4981 atttttgata caactcgtta aagaaagtct catcatttac taaatctaaa aattctttct
     5041 tgtctttacc agttaccttc gctacccgct cagcaatctg atcgatgtcg tagccttctg
     5101 gaatggcaat tttcccatct gcaacttttg ttggctcaga tgtgccgcct tcttgcaact
     5161 gcttgccaat ctcatcaaga gtcatattag gcgctaactg ataataacca gcttgaaagc
     5221 cagttaagtt tttaaatttt gtataataat tgaaaacaat cccactttta ataatattgt
     5281 ctttctccaa aatttcgcca atctgcttat tagaagagcc gcttgggatt tccacttgga
     5341 ctaattggtc gtccgattta tctaaaggct tcaacccgct atctacataa cgatatacgg
     5401 taaacccgag aaatccgcca ataatcaata atgtaagagc gatcactaaa atgatcttcc
     5461 tcacgatctt atcttctttt ttacgcagat ttctccgctt gtcgattata tctgctgtag
     5521 ctgccttact ggcttctttt ttgtctttgc ttgggtgttg tttgtttcct gacaaaacaa
     5581 ctcctcctta ctatcatctt cgtaactctg tttattatac atgaaatttc tactgccgtg
     5641 aattatttta ccaaatatta tgtcaaaatt gtaagtggca aatgctcttt ttgaggatta
     5701 caatgaaaaa tagttaaaaa tggataggaa ggatttaata tggcaaaagg aaaacatcaa
     5761 aaaaaacagc agatctctct ttcttttctc gcagttttgt tgctggctgt cagcttcttt
     5821 tcaacaggca tcattacagg atggcaatta acaaaacaac ctcaaccaca aatttataaa
     5881 acggaacccg cacaacttgc ttccaattta acatctaatg agcagatgct tgccagcaaa
     5941 attgatcaat tactgcaaaa atcagattat atcggttcga tttatgtacg caaaaataat
     6001 cgagtgatat tagaaaaagg atatgggtac gcaaatctac gcataaaaga attgaattct
     6061 ccttctcttt actatcaaat cggttcgatc caaaaagcga tgactgcttt acttatccta
     6121 aaacaaattc aatctggcaa gataactttt gacacaaagc tatctgaatt ttatcctcag
     6181 attcctggaa gtcagcaaat ctcaatcaaa aatatgcttt acatgcgctc tggtcttcat
     6241 cgaaccgctt ctccaaaaaa acctatgtca gatagtgaga tcattcagtt tgcccttcat
     6301 catttgaaat ttactggtta tgatacgtat cattatgaac cattaaatta tacattgctt
     6361 acaggggtat tgatcaaact aatgaatcag ccttatgaaa ctcttttaaa aaaagaaatc
     6421 attcggccac tccatctaga acatacagat ttttatgaaa atgtaaaaaa ttccccgcag
     6481 catgctgtat cttaccaaat gtctgcaact gacgattatt caaaagcatt ggtcgagcct
     6541 gaaacagaca tccgaaatga attaggcaca ggaaatataa gtatgtctgt ttatgacttg
     6601 aacaaattct ttaccagtgt tctgtctggc gatattatac caaaagaact acttttctca
     6661 ttgtggcaaa ataatggtga taaacatcct tacagcggcg gtgtttacag tggaaatgat
     6721 tatatccttg ctcagggaaa tatcaatcga ttccatgcag tagcggcgat gaaaaaagac
     6781 acaaaagatg caatcgtcat ggaaagtaat atccaatctg ataaaaacat caaattgccg
     6841 gccactgatt taagaaatca gatttacgaa ctgatggaag gtgttaattt aaaaagctaa
     6901 gtcgagacaa aaaaaccagc aggatgctgg ttttttgttt caatcgattt ctgtctttaa
     6961 ataacgttcc attccgttca atatatcaaa tttgggttga taacctaaag aacggatctt
     7021 tgaaatatcc gctaaagaat cacgaatatc ccctgaacgc tccgcttcat atttaagcgc
     7081 tagctctgtt cctaagattt gatcaattga atgaatcaat tcaagtagcg tagtgctttt
     7141 tcctgtaccg acattgaatt gctgtcctaa agctttttct tccttagcaa caagtaaaag
     7201 tgcttgtata acatcttcta tataaacgaa gtctctagat tggctaccat caccaaataa
     7261 agtaaattct gttttttctc ctgccaattg ttttttgtat cggtccacta gaatcgaaat
     7321 aactccgcta tatggagagt taggattttg atttggacca taaacgttaa aaaatcggac
     7381 agcactagtc ggaacatcat ataaatgaca gtaatccaaa acatattgtt ctgctgcaaa
     7441 cttatcgatg gcatatggtg ttaaaggacg gatgaccgat tcttcttttt ttggcaacgt
     7501 tggttcatcg ccataaactg cagctgatga actaaatacc aatcgtttta aaccagattg
     7561 atattttcgt accaattcaa gcaataaaag cgcactgtca aaatttacac gatgagtttc
     7621 tagaggacgt tctacagaat ctgccacact agctacagca gctagatgga aaatataatc
     7681 gaaatggtat tctttcatga ccttttccat caaatttttg tcagcgacat ccccttcaat
     7741 aaacgtgatg tgcttcgatt catccagatt ctcttttttc cccatcgata aatcatcgat
     7801 cacaactaca ttgttttctt ttcctagata attcgcgagc gtcgagccaa tgaagccggc
     7861 gccaccggta atcaagtaat tcaacatttt ttctcctctt ttcaagataa aatttattac
     7921 taaaaatagc tagaattatt tttgctatta actcttccta aaaatagcca aaaaacaaac
     7981 gttcctacag tgttttcata gactaattca ttgttaagag ctgcgtatag tgcataagat
     8041 aaaataacta aacagtaaac aaaatgataa tctttaccaa tgcatttatt atagatgatt
     8101 cgataaacat tcagcacaaa actctttatt aaaaaagcca tgaaaggaat tattcctaga
     8161 atacctgtcg atgttaatac attcaagtat gcattatgaa tggcaattcc tactttcgca
     8221 atatatccat ctggaataat tgactgtgca taagatacta catttttcgg agagactccg
     8281 ataagccaac ttgttttaaa tatttcccat gcacttttcc atatagtaat tctagcatta
     8341 gaaatatctg tattttcagc tacgtctttc ctaacaagag tattatcagg tgtttgagta
     8401 ttattaatat gttgactatt attcattaat tctttatgac gctctgtaaa attaaaaaaa
     8461 tttatttctt ttaaatgagg taataattct tgaaaaagta tcttagttgc attaaacaaa
     8521 gcgaataaaa tcagaacaga accaatagaa gatactatag caaggatata gttttttaaa
     8581 tctttttttg ttccatttcg ttttaacaca acaataaaag atgatatggc aactattatt
     8641 atacttacca cataggtaga tcgtgaccca cttaatacta tataaataaa ttgtaatgga
     8701 agattaatta aaaaaatgat tttatttaat cctgtcactt ttttattata aagataaaat
     8761 aagattagga caataacaac taaagatgct atagcagcat tgttaatatc agaaaacgtc
     8821 ccaaacagtc ttgattctaa aaaaccaatt ctgatcctat gtctagcatt ataatatttc
     8881 tcatagccga atttaccaaa gaaaagaacc attgacattg atactaaaac aaaccaacta
     8941 taaataaatc cccaacttat ccttttaaaa aatcgtttat tatcgctatt ctcaaaagca
     9001 aactgataaa tcaaaaaata ctgtaagatt gcccacatta tagtctttaa gttttctcct
     9061 agaccatatt ctttatgaac aaaactcgtt attactaaaa tcaccatata tgct
//
LOCUS       DAZKNV010000084         9019 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000084 DAZKNV010000000
VERSION     DAZKNV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.085"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            127..372
                     /locus_tag="ACG8M1_002499"
     CDS             127..372
                     /locus_tag="ACG8M1_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423163.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(556..1305)
                     /locus_tag="ACG8M1_002500"
     CDS             complement(556..1305)
                     /locus_tag="ACG8M1_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0423164.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            1491..2195
                     /locus_tag="ACG8M1_002501"
     CDS             1491..2195
                     /locus_tag="ACG8M1_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFQ0423165.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            2235..2792
                     /gene="hxlB"
                     /locus_tag="ACG8M1_002502"
     CDS             2235..2792
                     /gene="hxlB"
                     /locus_tag="ACG8M1_002502"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFQ0423166.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            2800..3939
                     /locus_tag="ACG8M1_002503"
     CDS             2800..3939
                     /locus_tag="ACG8M1_002503"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFQ0423167.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            3951..4382
                     /locus_tag="ACG8M1_002504"
     CDS             3951..4382
                     /locus_tag="ACG8M1_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0423168.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            4396..5841
                     /locus_tag="ACG8M1_002505"
     CDS             4396..5841
                     /locus_tag="ACG8M1_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFQ0423169.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            6127..7752
                     /locus_tag="ACG8M1_002506"
     CDS             6127..7752
                     /locus_tag="ACG8M1_002506"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0423170.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            8384..8737
                     /locus_tag="ACG8M1_002507"
     CDS             8384..8737
                     /locus_tag="ACG8M1_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423171.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
BASE COUNT         3103 a         1269 c         1774 g         2873 t
ORIGIN      
        1 taatatcagt tatcaaattt cctgtaaatt ttcttgaaac tacagcatat tattacttca
       61 aaacaatcta cattttttat aaaaaaggaa atgaataact gaaaaaatta ttataggaga
      121 gaaaaaatgt caaaatctaa aaaaaatatc accataattg gtttaggctt aaccgtatat
      181 ttatttacag aatttgttta tagacatgtg aatttatttg cagaaccttt atttgtatta
      241 tacgaatcaa attcctcaat cgtcagtgaa cttgctaatt taatgatagc attgctgttt
      301 actcccgcgt tgagagtcat aactattttg gtctgtttag tgctattgtt ttttgttaat
      361 aaaaagaaat aacgtagtat ttcaaaagac aaagaagtgg gatgatgatt gctatagtat
      421 gttatacgtg gtgctaggta agtgagaata aacaaaaaag gaaacacgca ataaagttta
      481 tttcaaaact ttattgcgtg tttctttttt agatttttta tatctgttgc tttagtagtt
      541 accaatagtt ttcgcttaat caatcaaaac gattttttgt ttattgtatt ctttacgaac
      601 cttttcagga atttcttctg aaataagata ggtaaggtct tcaattggac cgacgatatg
      661 attactgatg gtgccgaatt tatcattagt tatcatccca agtacttcag tagaaatacg
      721 tatcatctca cgtttaatgt cggattcttg catagttggc acgctcgttc caacatctag
      781 atctatgtta taaataccca taatataaag gtcggctcga atgttttgta gttgcttata
      841 agcttgtacc ccaatattga tcatagattg tttataaaaa gtaccgccaa tattgataat
      901 ttccaaatta ggatgctgtg ctaatgctat ggcaatcggc gggctattgg taatgattgt
      961 tgcacgaaaa tcttgtggga tttcttttgc taaagccaag ttagttgtac ttccatcaat
     1021 gatgatgaca gattcttctt ttaaaaaagg gagggcttta tgagctaatg cagttttttg
     1081 ttcgctagct acagtttctc ggtagttaaa attggtaatt ggcggaccaa cacgtaaagc
     1141 gccgctgtgt actcttttta agagaccttg gctatccaaa tctttcaaat ctcgtcgaat
     1201 cgtgtcttcg gatacattga aacgttgact taaatcacta gcgataactt tttgttctgc
     1261 gtttaataaa tctagaattt tttgatgacg ttctaatttc aacatgttgc gtgctccttc
     1321 ttatttattc ttgtttatca tgtcatttat gcgtttttat gtcaataatt tccgttttta
     1381 atacactaaa aaggcataaa caagcaaaaa caaaatattt ttatgcagtt ttatgttgac
     1441 tagtatttgt taagcggtta caatgagggg gtaattaaag gagggaatgt atggagaaaa
     1501 aaattatttt gtcgccttca cttatgtgtg gggatctagc aaatttggaa ggaagcatcc
     1561 aagaactaga aagtattggg atggattcct tgcatattga cgtgattgac ggttctttta
     1621 gtcccagtat gcctttaggg atcgaaacaa tcaaaagaat tagagaaatc acttcaatga
     1681 attttgatgt acacatcatg gctaaggata acgataacga attttttatt ggagaaatgt
     1741 tgaaaattgg cgtagagagc attacttttc attatgaaac aagcctccat attgatcgat
     1801 atatccagct catcaagaat tctggaacaa aagtagggat agctttgaat ccagcaactc
     1861 cgttaaatgt attacaatat attttacccg agattgatag gatttgtttg atgctgatta
     1921 atccaggttt tgcaacaaac aagtcagaaa aacaagtttc ttacgcgcta aaaaaaatta
     1981 cagatctttg ccagttagta aatgagaaag agttagcagt agatatccaa gtggatggac
     2041 gggtatcgtt agaaacgatc ccgggattat tagatgcagg cgcaacaaat ctggtattag
     2101 gaagtacaag tttgtttctt aaaggaaata cattagcaga aaatcaaaaa ctactttatc
     2161 aagcgatgaa gcaatcagtt aggaaaaatc aatagatgta gtggtcctga ataatagaaa
     2221 tggaggggaa atagttgagt tataaggcgg cgaaacaaaa tattgtaaga gaaattactg
     2281 aaacattaga ccgtatttct tcaaaagatg tggaacaatt gataaagaaa attgaaaaag
     2341 cggaacgagt ttttttcgtg ggggttggca gagtactgtt agcgctagaa ggaatggcaa
     2401 aacgcttagg gcatctagga attcagacag tagtcgtagg acaaatcact gaaccggcaa
     2461 ttacagataa agatttattg attgttggtt ctggtagtgg ggaaagtgct ttcccactaa
     2521 ctattgcaaa aaaagcaaag gaatttgggt cccaagttgc ccatatagga tcaaacccag
     2581 acagcacaat gaaagaatat tcagatcttt ttattcgtat acccgtacaa acaaaattag
     2641 cgttaccaga ggaaatttct tctatacagc caatgactag cctgtttgaa caaagtgttc
     2701 ttttgttagg agatagtatt gctttagtga tgatagaaga aaaagcaatt gatatgtcaa
     2761 agttgtggca ataccatgct aacttagagt aggtgaaaaa tgaaagcggt acattttgga
     2821 gcagggaaca tcggcagagg gcttattgga caaattctac atcagaatgg attcgatcta
     2881 tgttttattg atacgaatcc tgaactgatc catcaattaa atcaagataa gggttatact
     2941 atcgaaatta ttgatgaaat gaacaggagt gatttcattg atcatgttgt ggcactgaat
     3001 agtttatccg agctagaaga ggtgattaca gcaacaaaaa atgcagatat cttaacaaca
     3061 tctgttggcg caataaattt agtaaaaatt gcaccgatca ttgcgcaagc cttaagtaag
     3121 cgatttgaac aaaagcatag catcaatatc gtagctaatg aaaatgtgat aaatgcaagt
     3181 gatgtgttga aaaaagaaat ttattctttg ctgtcagaaa aagaacaaga gaattttgat
     3241 gaatatgcat attttgtgaa tacggcaatc gatcgacaat ctttaggaaa agttcttgga
     3301 ggaaaaatga tctctgttgt cgaaccttat tatgaatgga taatggatcg acagcagtta
     3361 gatccaacta catcttttga tatgaaaaat gtaaatttgg ttgatgatat ggagccttac
     3421 attgagcgaa agctttatat cgttaatgct gctcatgcgg cagtagctta tttaggcgca
     3481 ctgaaaggat ataagacgat tcaagaagca atccaaaata tggagatttt caatctagtc
     3541 aagcaatttt taatggagaa tatagagtac tttgtacaaa aatatcattt ttctagagaa
     3601 gaattaacat cttttgtgga aaaaacatta aaccgtcatg ggaatcagaa actctccgat
     3661 gaaattactc gtgtaggaag ttcccctatt cgaaaattag gccctaatga tcgtttaatt
     3721 gctcccatag taaaactaga ttcatatcat ttaccttacg atgcaggaat aaaagtaatt
     3781 gctgcgggat atcattatcg gaatcttgct gatccagaag ctgaacaact acgtcgaatg
     3841 attgtaaatg atgggttgaa agcaacgatt aaaaagattt ctcgtttgga aggtaagctg
     3901 ctgaatgaag ttgtcgctgc ttatgagtcc cagatttaga ggaggagaat atgctaaaag
     3961 aacaattgtc aggaaataca atgtttatgg atgcgatcga ttcatggcaa gaggcaatcc
     4021 gagtaagtgc gcgtcctttg ataggaaagg gaataataga ggaaagctat gtacaagcga
     4081 tgatacaaaa tgtgttggat aacggaaatt atattatatt actgccacta gtagcaatgc
     4141 ctcatgcgcg tccagaattt gggagcaaag gggtcgggat gagcttttta tgtttagata
     4201 agccagtcat gttcccaagt gaagaaccag taaaattctt ctttaccttt tcttctgatt
     4261 cgccaaaggg acatttagac ttaatggcca atcttggaga attgctgagt gatgaaaaaa
     4321 tgtatcaaaa attattcgat gtgaagacag aaaaagcatt gttagatttg ataaagaagt
     4381 aaaggagaga agaaaatgga ggtagcaaac aaaaaaaaac gagtctccat gcgagctaaa
     4441 gttcaagcga ttggcggttt cttaacaaat atggtattgc caaatatagg cgcatttatt
     4501 gcatggggaa ttgttactgc attattcatt ccaactgggt ggttcccaaa tgaatctctg
     4561 aatgaactcg taagtccgac agtcagctat ctattgccgt tactacttgc ctatactggt
     4621 ggtcggatgg ttggtggtac acgtggagct gttttaggta caatcggaac aataggtttg
     4681 attattggtg ctgacatacc aatgttcatg ggagcaatga ttatggggcc acttggtggg
     4741 tggatgatga aaaaaacaga tgatttttta gatgggaaag ttcctgctgg ttttgaaatg
     4801 gtcgtcaata atttttctat aggaattatt ggtttcatac tgatgtgcct ttcttatctg
     4861 gtagttggac caataatcca atcagctaat caatttgtaa cgagtgcaat tgaagcatta
     4921 gtttcaactg gttttttacc gatactgtcc ttaatcaacg aaccggcaaa agtcttattt
     4981 ttaaataatg ttattgacca aggtgtttat tatccattag gtatgcaaca aacattagag
     5041 gcaggcagat caatttattt catggtagca tcaaatcctg gccctggctt aggactattg
     5101 ttagcttatt ctttatttgg taaaaaggca gcaaaacaga cagcaccagg tgcaatcatc
     5161 atccattttt tcggcggaat acatgagatt tattttccat atgtattaat gaaaccactc
     5221 actatattat ctatgattgc tggtggaatg acaggaatca tcacttttga attatttgat
     5281 gcgggcctgg tagcaggtcc aagtccaggt tctatttttt cttatttagc tctaacgcct
     5341 cggggaaatt ttttgggtgt catggcggga gtggtcacag caacactggt ttcctttttt
     5401 gtaacatcag taattttaaa agcagataaa tcaacagatg aagacagaaa ttttgaacta
     5461 tcagttcaaa aatcgaaaac gatgaaatca gaaggaagaa aattattaaa agaagaaaat
     5521 gctagagaaa tatgtaccga gaaaaaagag atgaataaaa tttcctttgc ttgtgatgca
     5581 ggaatgggaa gcagcgcaat gggcgcaaca atattcaaga aaaaattgca aaaagcaggt
     5641 attactgatg ttgagataaa aaattatcga attgaagagg taccagaaga tagtgatttg
     5701 gtgatcgtac atcaagattt ggaggaacgg actagaaaag cacatcctaa catgaaaatt
     5761 gtgacattaa agaattattt gcaagatcca gtaatcaatg gattagcaga agaaatcatt
     5821 ggattaaaaa cagaagacta atttatggga atttttgatt aacctttatt aaaattattt
     5881 tgcctaatat aaaaaggttg tgacatggct tgtgtcgcaa cctttttttg tcgcacaaat
     5941 aattaatcgg atattttatg ttcatatttt ttgtgatcaa cgagaactga tggggcaaag
     6001 atacatttta gatactttta actgttaatt tacaaaacaa ggtgaaacga atagaaaaat
     6061 gaaaaaatcg atacggaaga atatgtttga ttaaaacatg catgaagaga aggaggttga
     6121 tgatacatga aaaaaatata ttcaaaggaa atcgattgtt ttagaggcat tgctgtttta
     6181 gcagtgatat tttatcattt gccaaatagt ttgctgccag gcggattgca aggagtaacg
     6241 atcttttttg tggtttctgg ttttttaatg gctaaaaata cgataagaga tgaaaaaaac
     6301 agacaattca gttttttaca tttttactat aagcgtatca aacgtattta tccattttta
     6361 ctgttttctt tggtcgtatt cattttcata ctagggatta gcaacattcg attgatagga
     6421 aacattcgta gtgagctacc cagtttgatt tttggctata acaattggtg gcagctgaat
     6481 caaggagtat cttattttga ctcttacttt aatgcttctt tatttaaaca ttattggtcg
     6541 ctttcagttg aactacaatt ctatttgata tggccatttt tgtttattgt cattaagcgt
     6601 atgagaagaa aacaagtgtt ttacttaatc tatacattga tttttgtttc tattcttttt
     6661 agtttgtttt taccttcaac taaggcatat tatcatacga tagctaaact ttttccattt
     6721 ttattaggag tttgggggta ttttaatcga ataactattg gccgtttctt tgaacaaaac
     6781 acttttagta aaatctggct tttattacta gctagtcttt gtctgattct gttcccgatt
     6841 tttccttata cactaaatga actactgatc agtatttgtt ttgctctatt gttagccagt
     6901 gtcgatgata tgaacattgc aaaaaagacc aaaatcgcta gtacaaaact ttcttttgta
     6961 ggaaaaatca gttatgaact ttatttggtg catttcccag tattgattgc tctgacaaat
     7021 ctattcaaac atcaccattg gaaatatttg gatatcgcag gtctattcac tgtgttttta
     7081 tgtacattac tcatgattac ttgctttaga aaaggagtgc aaaagatgag atcacccaaa
     7141 atttggacag ctatggcact aatgataatc ggagtttctg tactggtatt acgtgctcct
     7201 gccagtcgac tgaccgctga ccaaaatcag ttgcaaagtt tattaaaaga aaactctagt
     7261 aaagcaaatg caggagaaaa tctgttgtca caagagaaga aaatattatt tatcggtgat
     7321 tctgttatgc tgggggcgta tcaggaacta aaggagacat ttaaaaaaga agcattggta
     7381 gatgcaaaag aatcaagaca aatcactgcg ttaccagaaa tcttaaagga gcataaagat
     7441 ttagtttctt accaacaaat agtgatcggg ttaggaacca atggtgtgat aacagatgaa
     7501 gctatagaac aaacaatgtc tttgctgaaa gataaaaaag tatactgggt aaatataaaa
     7561 gcaccaactg gctggcaaga tacgataaat gccacattag ctacattgcc aaatcagtat
     7621 tctaatataa cgatgatcga ttggtatagt gagagcaaaa atcatcctga atttttttat
     7681 gatgatgaaa cccatttgaa tgaaagtgga cgtacagctt atgcaaagta tattgcttca
     7741 gttattcaat aaggtagtga ttacgtgtgt taaccttact ttttcctaat aggtgaatca
     7801 atttaaataa aaaatacttc atatgataaa cggtgtttaa gaggaggagc tttttaatat
     7861 tcgtggtaaa aaagagatgg gcgaggtcgt taactgagag cttcttggaa agaaatcgct
     7921 ttggatttat cctctttgtt atacagaaca tgagcgagac gacaatacta ggatgtatgt
     7981 tctgatcgaa gttttatggt tacaagcagc aatcagctta gataaaatta aggatcgtag
     8041 gaaccaagta aagaaggctg ttagtaaaga aacaaacgat caagtatgtt ttactcttaa
     8101 gaagatgcag tgaataaata atagtaatat aatgctagaa gggactgtga caaaagacgt
     8161 gtcacagcct tttttgttat tttaattatc gtccagtctt tttttataaa tgattgctta
     8221 agcattaaat attaaaaaat atagagttca aaattactgc acaattagat gaaaaatttg
     8281 aacaacaaaa agtgtatttt tatactataa tagcttttga atttagttac tctattcaaa
     8341 agttatgcta tggacaagaa aaagaataaa tagaggtgag aaaatgaata gtttcaagaa
     8401 aaaatttgtg agtagatttt taaatatgaa aaattttttt gaaaaaaagg gagattatga
     8461 tgcatataat tatgtattaa atctagaaaa gcaaacatat tatacactac gtaaaaacga
     8521 tgataatgac ttttggacta tgttacctaa aatgctttcg attgactcta agctttccct
     8581 tttagaggaa tttattaatt tagacattga agaattttgc gggggaaaag agttaattaa
     8641 tatggtagag agtgattatc atacctatta taaagaaagt tgtggataca aagtggatga
     8701 gcaatgtcca caatcaatta ttttttacat tgagtaatat gaactattaa gcaggaaagc
     8761 aactagaagc tactgattta gtatttacaa atataaacta tattgctaac aattattttc
     8821 tagaaggaat aaaagaacta agaatcaaga cgttatcttg attcttagtt cttttaacat
     8881 ggaaaagatg gataatgcac tgttaattca tgatgcatca tcagaaaagt tggaaggaga
     8941 agatagaaat cattaaatga tttctacaga tggtaaatga aaaaacaaaa tattagcaaa
     9001 aatttgccta aatagatag
//
LOCUS       DAZKNV010000085         9015 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000085 DAZKNV010000000
VERSION     DAZKNV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.086"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            70..153
                     /locus_tag="ACG8M1_002508"
     CDS             70..153
                     /locus_tag="ACG8M1_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFQ0423172.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            278..1015
                     /gene="erm(B)"
                     /locus_tag="ACG8M1_002509"
     CDS             278..1015
                     /gene="erm(B)"
                     /locus_tag="ACG8M1_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFQ0423173.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1185..1445
                     /locus_tag="ACG8M1_002510"
                     /pseudo
     CDS             1185..1445
                     /locus_tag="ACG8M1_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1608..2273
                     /locus_tag="ACG8M1_002511"
                     /pseudo
     CDS             1608..2273
                     /locus_tag="ACG8M1_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2309..2554
                     /locus_tag="ACG8M1_002512"
     CDS             2309..2554
                     /locus_tag="ACG8M1_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0423174.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2657..3526
                     /locus_tag="ACG8M1_002513"
     CDS             2657..3526
                     /locus_tag="ACG8M1_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0423175.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLLECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3507..4241
                     /locus_tag="ACG8M1_002514"
     CDS             3507..4241
                     /locus_tag="ACG8M1_002514"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0423176.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4274..5182
                     /locus_tag="ACG8M1_002515"
     CDS             4274..5182
                     /locus_tag="ACG8M1_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFQ0423177.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5179..5721
                     /gene="sat4"
                     /locus_tag="ACG8M1_002516"
     CDS             5179..5721
                     /gene="sat4"
                     /locus_tag="ACG8M1_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFQ0423178.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5814..6608
                     /locus_tag="ACG8M1_002517"
                     /note="aph(3')-IIIa"
     CDS             5814..6608
                     /locus_tag="ACG8M1_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFQ0423179.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6884..7015
                     /locus_tag="ACG8M1_002518"
                     /pseudo
     CDS             6884..7015
                     /locus_tag="ACG8M1_002518"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            7091..7836
                     /locus_tag="ACG8M1_002519"
                     /pseudo
     CDS             7091..7836
                     /locus_tag="ACG8M1_002519"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7947..8126
                     /locus_tag="ACG8M1_002520"
                     /pseudo
     CDS             7947..8126
                     /locus_tag="ACG8M1_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibD"
     gene            8229..>9015
                     /locus_tag="ACG8M1_002521"
     CDS             8229..>9015
                     /locus_tag="ACG8M1_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFQ0423180.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNI"
BASE COUNT         3162 a         1401 c         1873 g         2579 t
ORIGIN      
        1 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
       61 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      121 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      181 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
      241 atttatttac agatgtaatc acttcaggag tgattacatg aacaaaaata taaaatattc
      301 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      361 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      421 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      481 agaaaaatta aaactgaaca ctcgtgtcac tttaattcac caagatattc tacagtttca
      541 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      601 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      661 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
      721 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
      781 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
      841 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      901 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      961 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1021 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1081 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1141 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1201 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1261 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1321 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1381 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1441 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
     1501 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
     1561 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
     1621 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattagaa gaaaatgatt
     1681 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
     1741 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     1801 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     1861 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     1921 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     1981 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     2041 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     2101 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     2161 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     2221 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     2281 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     2341 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     2401 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     2461 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     2521 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     2581 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     2641 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     2701 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     2761 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     2821 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     2881 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     2941 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     3001 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     3061 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     3121 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     3181 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     3241 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     3301 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     3361 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cacttttgga
     3421 atgctacgac atgaccgaga agctttataa tgaagtgaat gaaattgtat cggagataaa
     3481 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3541 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3601 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3661 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     3721 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     3781 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     3841 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     3901 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     3961 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     4021 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     4081 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     4141 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     4201 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     4261 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     4321 acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc
     4381 taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag aaccgtttat
     4441 atctaatgat gactggctta atcaatttgg gaatataata atgatgcaaa agccggagga
     4501 tatggaatta ttcccacctg aagaaaaggg attttcctat cttatgctat ttgatgatta
     4561 caataaaatt gatcttacct tattgccctt ggaagagtta gataattacc taaagggcga
     4621 taaattaata aaggttctaa ttgataaaga ttgtagaatt aaaagggaca tagttccgac
     4681 tgatatagat tatcatgtaa gaaagccaag cgcaagggag tatgatgatt gctgcaatga
     4741 attttggaat gtaacacctt atgttattaa aggattgtgc cgtaaggaaa ttttatttgc
     4801 tattgatcat tttaatcaga ttgttcgcca tgagctgctg agaatgatat catggaaggt
     4861 cggcatcgaa acaggcttta aattaagtgt aggcaagaac tataagttta ttgaaaggta
     4921 tatatccgag gatttgtggg agaaactttt gtccacctac cggatggatt cctatgaaaa
     4981 catatgggaa gcattatttc tatgccatca attgttcagg gcggtatccg gtgaggtggc
     5041 ggaaaggctt cattatgcct atccggagta tgataggaat ataacaaaat ataccaggga
     5101 catgtataaa aaatacactg gtaaaaccgg ctgcctggat agcacatatg ccgctgatat
     5161 agaagagagg cgggaacagt gattacagaa atgaaagcag ggcacctgaa agatatcgat
     5221 aaacccagcg aaccatttga ggtgataggt aagattatac cgaggtatga aaacgagaat
     5281 tggaccttta cagaattact ctatgaagcg ccatatttaa aaagctacca agacgaagag
     5341 gatgaagagg atgaggaggc agattgcctt gaatatattg acaatactga taagataata
     5401 tatctttact accaagacga taaatgcgtc ggaaaagtta aactgcgaaa aaattggaac
     5461 cggtacgctt atatagaaga tatcgccgta tgtaaggatt tcagggggca aggcataggc
     5521 agcgcgctta tcaatatatc tatagaatgg gcaaagcata aaaacttgca tggactaatg
     5581 cttgaaaccc aggacaataa ccttatagct tgtaaattct atcataattg tggtttcaaa
     5641 atcggctccg tcgatactat gttatacgcc aactttgaaa acaactttga aaaagctgtt
     5701 ttctggtatt taaggtttta gaatgcaagg aacagtgaat tggagttcgt cttgttataa
     5761 ttagcttctt ggggtatctt taaatactgt agaaaagagg aaggaaataa taaatggcta
     5821 aaatgagaat atcaccggaa ttgaaaaaac tgatcgaaaa ataccgctgc gtaaaagata
     5881 cggaaggaat gtctcctgct aaggtatata agctggtggg agaaaatgaa aacctatatt
     5941 taaaaatgac ggacagccgg tataaaggga ccacctatga tgtggaacgg gaaaaggaca
     6001 tgatgctatg gctggaagga aagctgcctg ttccaaaggt cctgcacttt gaacggcatg
     6061 atggctggag caatctgctc atgagtgagg ccgatggcgt cctttgctcg gaagagtatg
     6121 aagatgaaca aagccctgaa aagattatcg agctgtatgc ggagtgcatc aggctctttc
     6181 actccatcga catatcggat tgtccctata cgaatagctt agacagccgc ttagccgaat
     6241 tggattactt actgaataac gatctggccg atgtggattg cgaaaactgg gaagaagaca
     6301 ctccatttaa agatccgcgc gagctgtatg attttttaaa gacggaaaag cccgaagagg
     6361 aacttgtctt ttcccacggc gacctgggag acagcaacat ctttgtgaaa gatggcaaag
     6421 taagtggctt tattgatctt gggagaagcg gcagggcgga caagtggtat gacattgcct
     6481 tctgcgtccg gtcgatcagg gaggatatcg gggaagaaca gtatgtcgag ctattttttg
     6541 acttactggg gatcaagcct gattgggaga aaataaaata ttatatttta ctggatgaat
     6601 tgttttagta cctagattta gatgtctaaa aagctttaac tacaagcttt ttagacatct
     6661 aatcttttct gaagtacatc cgcaactgtc catactctga tgttttatat cttttctaaa
     6721 agttcgctag atagagttct atattagaga tgtaaagagt tttggtgaag aggtttgtga
     6781 gtatggcttt tataaccagg gtgcaatgag aagcactaac agcagctagc ttaagaacgc
     6841 ataggatata ctttttatgg aagtcacaga ggaggaataa aatttgaaca ggattaacag
     6901 agtaacctct attcttattc agctgcaatc aaaaaaaata attcctgcca aagaaattgc
     6961 acagcgattt aatataagct taaggacagt ttacagagat atccggacac ttgaagaagc
     7021 cggaatacca attggatctg aggccggaaa aggatatttt cttgtagagg gcttcctact
     7081 tccgccggta atgtttacag cggcggaagt gggtgcattg attacagcag ggaaattttt
     7141 aaattgccat ggagatgaat catttataaa ggattttgat tcagctatgt ataaaatcaa
     7201 atctattttg aagcatggtg aaaaaaacta tgcacaggag ttggagaaca gtattaacgt
     7261 gtacagcaca tctggacaga aaaatacatt ggcggataac gttattgcag caattcagac
     7321 tgcaatctgc aataaaaggg taatatcaat tcaatatcct gcatcaggag ggcaagaacc
     7381 ggaaagcaga atgatagagc ctatatcact ggggttttat gaacagaact ggtacttaat
     7441 cggttttgca ggctaagaaa tgaatatagg aattttcgtg tggatcggat taaaagcatt
     7501 tgcatagaag aagagctctg tcaaagccat gatggctctt tggaacaaat attaaaacaa
     7561 atgctttcat ataaaaaact atataatgta attcttagag ctgaaaaagg ggagacatac
     7621 aattctatca agaacaggta ttctctcggc ttccttgaag aaaccgattt gggaagtaaa
     7681 atggaaatcg aattccagac agattccttt gagatattga gcaagcagct gattgaatat
     7741 ggatcaggca ttgaaatagt ccaacctgat gaattaaaat gcataacccg taaacacctg
     7801 gcacaaatta cgaatcactg cctaaacttg atttagagaa agcgattggt ctgttatgta
     7861 ttttttgtaa ggtttcatat cccctgctga catacagctg tcagtgtatt atgatattct
     7921 actatcaaaa aggaggattg aaaaatatga aaccaaagat aattatgcac acacaaatta
     7981 gccttgatgg ccgcattaaa ggctttgata atccggaagt ttactaccag gttgccgggg
     8041 gaattcattc ggatgcggtg ctgtttgggt ccaatactgt ttttactgca tttgaaaaat
     8101 atcctgctga aacagaggct gattttggat aaagtccgta taattgtgta aaagtaaaaa
     8161 ggccatataa cagtcctttt acggtacaat gtttttaacg acaaaaacat acccaggagg
     8221 acttttacat gacccaagta cattttacac tgaaaagcga agagattcaa agcattattg
     8281 aatattctgt aaaggatgac gtttctaaaa atattttaac aacggtattt aatcaactaa
     8341 tggaaaatca acgaacagaa tatattcaag caaaagaata tgaacgaaca gaaaaccgac
     8401 aaagtcaacg aaatggctat tatgagcgca gctttacgac acgtgtaggc acgctagaat
     8461 taaaagtacc cagaacacgt gatggccatt tttcacccac agtgtttgaa cgttatcaac
     8521 gaaacgaaaa agccctcatg gcttcaatgt tggaaatgta tgtatcaggc gtttcaactc
     8581 gtaaagtatc aaaaattgtg gaagaacttt gtggtaaatc cgtctctaag tccttcgttt
     8641 ctagcttaac agaacagcta gaacctatgg ttaacgagtg gcagaatcgt ttattatcag
     8701 aaaaaaatta tccttactta atgaccgatg tactctatat aaaagtacga gaagaaaatc
     8761 gagtactctc aaaaagctgt catatagcga ttggaataac caaagatggc gaccgtgaaa
     8821 ttatcggctt catgattcaa agtggcgaaa gcgaagagac ctggacaaca ttttttgaat
     8881 acctaaaaga acgcggttta caaggtacgg aactcgttat ttctgatgcg cacaaaggat
     8941 tagtctctgc cattagaaaa tccttcacca acgtaagttg gcaaagatgc caagttcact
     9001 tcctaagaaa tatct
//
LOCUS       DAZKNV010000086         8900 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000086 DAZKNV010000000
VERSION     DAZKNV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.087"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(516..740)
                     /locus_tag="ACG8M1_002522"
     CDS             complement(516..740)
                     /locus_tag="ACG8M1_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423181.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            931..3708
                     /locus_tag="ACG8M1_002523"
     CDS             931..3708
                     /locus_tag="ACG8M1_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0423182.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            3789..4208
                     /locus_tag="ACG8M1_002524"
     CDS             3789..4208
                     /locus_tag="ACG8M1_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0423183.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4220..4690
                     /locus_tag="ACG8M1_002525"
     CDS             4220..4690
                     /locus_tag="ACG8M1_002525"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0423184.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4707..5486
                     /locus_tag="ACG8M1_002526"
     CDS             4707..5486
                     /locus_tag="ACG8M1_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0423185.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5473..6294
                     /locus_tag="ACG8M1_002527"
     CDS             5473..6294
                     /locus_tag="ACG8M1_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0423186.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6311..7360
                     /locus_tag="ACG8M1_002528"
     CDS             6311..7360
                     /locus_tag="ACG8M1_002528"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0423187.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7373..8377
                     /locus_tag="ACG8M1_002529"
     CDS             7373..8377
                     /locus_tag="ACG8M1_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0423188.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT         2967 a         1472 c         1837 g         2624 t
ORIGIN      
        1 ttatagatga aactctattt acttcttttt taatttgttc ttgcaatctt ttttgctacg
       61 taatttttgt aaaaaagtgg gttgagagaa atctaattga ttttcaaaga aggagtatga
      121 aaatgagaaa aatatttatt cgtttattgt gggtactatc ttagaggaat aaataatagt
      181 ggagaaaact atggtttggc gcagattcta tcaggtttga tggaacgaag acaacctccc
      241 gacatcaagt caaaagctac ttgagatttt gatctgaaaa taaaaaaaga aaacaaggta
      301 ggaacatcaa tgtttctacc ttgttttcgt aatcaatggg aaaaaactaa gagtggtgta
      361 cgtaatcaat aaaaaggatg gtgacaacag tacctcttta ctctctgaaa gcatcataac
      421 tcgtttttcc tcattatgcc aataaattgt tgttatacca catataagga tttgtaatag
      481 ctaaaaacag acaggaaagt tgaaatctgt gaatcttatt ttgtatggaa ggatttatag
      541 aacgcaaaaa tcaagataaa gatgaataaa aatcctgttt cggctatata ttgcgtatct
      601 acgccaataa aacgagtttg ttctgtcata gccatataaa gcaaaggcaa aaatacaact
      661 acagcgagat aagatccgat gatttctcga aaagttttcc aggaagtatg tttcctgttt
      721 ttatatttat ccgatttcat tgaatagtca tagcctcctt attctttcat atgttgaaat
      781 tccagtataa aaactggaag gaactgtacg ttttttagaa taaaaattat aagggataag
      841 taggctgctg tctataataa gatatatttt tcaattcttt attaaagatt ttattgacaa
      901 aatgaatccg ttttctatga tggaggaggg gtgaataagt tgttgaagaa ggaaatttta
      961 tgttacttag agaaccagac agcctttttc gatttagaac atatgaacga ggtctttaca
     1021 gcacaaaggt tagctgatca ttttggggta aaaagaaaca cagtcagtca ttatttgaac
     1081 cagttaaatg atgagcaact actagtcaaa atcaattctc gaccagtgat ttatttccac
     1141 aaagaagctt ttgaaaaaca attttttaag ttacgcacga atttttattt ttctatcgat
     1201 gatctcaaag aggaacagcc ttttttcgcg caaccaaaag acttattctc ttttatgatc
     1261 ggatacgacg ccagtttgaa agaaagtatc gaacaaatca aaacagctct ttactatcca
     1321 gatggcggat taccactttt gattacaggc gaaagtggca caggtaaaag ttatttagtt
     1381 aatttggtct atcagtattg tctgcttcat gatctgctag aagattctgc accattcatc
     1441 acttttaatt gtgcacaata tgcagataat cctgaacttt tgactagcaa tttgtttgga
     1501 catgttaagg gagcgtacac tggtgcagaa gaaaataaaa aaggggcttt tgaagcagca
     1561 gatggtggga tcttgttttt agacgaggta catcgcttaa caccagaagg tcaggaaaaa
     1621 ctgttcacct atcttgatca aggtgtgatt tatcgtatgg gagaacctaa tttgtcacgc
     1681 cggatcaaaa cacgtctctt ttttgctacg actgaagaga ttactagtca tttcttaaca
     1741 actttcattc gaagaatacc tatccgaatc gaactacctg cacttaatca gcgtagtcgt
     1801 aatgaacggc tagaactgat ttactctttt tttctcgaag aacaaagaaa aatggggagc
     1861 cctttgtcag tcagtggacc agctttgtca cttttaacaa gtcagaaatt atccggaaac
     1921 ataggagagc tgaaaaatat cgtcaaagtt tcagcagcaa aagcatatgc tgaacagcgt
     1981 gaacagcctg aaatccatgt cacgatccat catttgcaaa aagaactact tgcgcagcct
     2041 attactaaaa atacagcaca gcaaggaatc tatattacgc aagaccagac cttagagcaa
     2101 ttaatggaga agcaacagcc cgaacagcag cgaatcgtta aaagttttga gcaaatccta
     2161 attgatttca agaaaaataa ctgtctgcta tattcttgcg aaggaaaatt aaagcaagaa
     2221 gtgattcaat tatttgattt tttgctgttt gagaccagta gacaagaaaa acacgagctg
     2281 ctggtttatt ggacacaatc tatccgagag acctttcgac aaatggaaac tgcctatcaa
     2341 atcaaattcg atggaaacag tgtctatgcc ttgagttact atctctatca gcgaagcact
     2401 atcaaatggt taccggaaga acatgatatt atccaactaa tcaaagaatt agaacaacaa
     2461 gtttctcagt cttatccatc tagttatcac tatgtccaac gaattctgga attaagtaag
     2521 atcaaattag atattgaaga cacaagtatg gatcggattt tactgacgat ctatctaaaa
     2581 aaagcgaaat ggtcaaaaga aaaacgactg ccaaaagcga tgattgctgc tcacggttat
     2641 gcaactgcta gcagtatggc aaatgtagta aatcgtttat tacaagagga tctatttgaa
     2701 tcatttgata tgccactaga tgtcacacca cagcagattg cttcagaaat ccttgattat
     2761 tgcgaaaaca gcgatgtttc aaatggattg atcatattag tagacatggg atctctgaaa
     2821 gaaatccatc agttttttaa aaaacagtta tccgtaccgc ttttgatttt gaataatgtg
     2881 acgacacctt tagcaatcac agtaggggaa tgcctgcaaa aaaatgtatc attagaagag
     2941 atagcagaag agactgttcg acagatccag ccagaatggc gactgctcta tccagaggaa
     3001 aacaaaccca aagcactcat tactacttgc ttcactggaa tcggtacggc ggtccactta
     3061 agtgaactgc tagaaaaaag cttacctacg gcttgtcagt tgaaaatcat cccatatgaa
     3121 tatcagcaat taaaagataa gaaaaacagt gacccattat tttccatata cgaagtcgta
     3181 ggaatgattg gcaccacaga tcctgatatc accaatatcg actatctttc attagaagac
     3241 ctcatctcgg gggaaaagat gtctgtacta gctgaatggt tggacactac tatgaatgct
     3301 tcagagaagg aaatattcaa tcagcgcatc attcgtaatt tttcattgga aaaagtactg
     3361 gattccgtga ctattctaga tacagagaag gtgatgggag aaatcgatca ttttatgaga
     3421 gaattagagg tgcagttgaa tcgaagcatc agcaatccca aaaaattagc gttgtatgtc
     3481 catgtgagct gtctcattga acgattgatc cgacaaatgc caatcgaaac ctatcaagga
     3541 ttagagaaat ggaagcagtg tcaaaaagaa gggttatctg ctattaaatc tgcgtttagt
     3601 gtcattgaag agcattatag tgtcatgatc cccaattctg agattgccta tatctatgat
     3661 attttgagtg aagatacaga gtttctctcg atagaagaag aattttgaac ataagcaagt
     3721 tgttgccact aattttggca tgcaacttgc ttttttagta tgtgtaagtg aaaagaggag
     3781 atgaaaaagt ggatagagaa attatcttag cttcccatgg aaaatttgct tcagggatat
     3841 tagattcatt agagctgatc tatgggaaaa atcattctat tactgtattc gattgctata
     3901 ctgatgagaa ttttgattta gcggaaacag taaggcagct ttttatgagg tacaaagata
     3961 aagaaatcat tgttctgacg gatctttttg gcggaagtgt caacaacgaa ttcttacaat
     4021 atatcaatcg ggatcatgtc tatctcgttg ccggattgaa tttgccacta ttgattgagc
     4081 tagtatctcg gttggacgct gaagtagaga caactgtttt gatccagcag gtgctaactg
     4141 attcaaaaaa aatgatccag ttttgtaacg agcggctcaa tcagaaaata gaagaagacg
     4201 aattttagga ggaagaaaaa tgattgtatt gacaagagtc gaccatcggt tattacacgg
     4261 acaagtagct ttttcatgga cacaaacaat aggcgcagac tgtattttga ttgctaatga
     4321 tgatgtacct acgaatgaga tacgaaagac aacgatcaaa ttagccaagc cacaaggagt
     4381 caaactagtg atcaaatcaa ttgatgactc gattgccgcg ttgaaaagcg gggtgacaga
     4441 taaatataag ttattcatcg tagtggaatc gatcgaggat gcatataagc tggcagaagc
     4501 gtatccagaa atcaaaacca tcaacttagg agggatcaag gcaaaacctg gtactcgcag
     4561 catcggaaaa gcggtaaata ttttaccaga agaggaggaa cgcttgaaac gattaattga
     4621 caaacaaata gaagtagaaa tccgtcaagt accagcagat aaaaaagtgg atgtaagaga
     4681 agttttgtaa gaaaggaaga acctcaatga ttgtacaagc agtcttatta ggaattgttg
     4741 catttgtcgc acaatcagaa tatgcactag ggacatcgtt gctttctcgt ccgattgtga
     4801 cggggctgtt tacaggaatc gtgttaggtg atgtaaaaac tgggatcatt atgggcgcaa
     4861 ctttagagtt agcatttatc ggatcgttct cagtaggtgc ttcgattcca cctgatgttg
     4921 tgaccggtgg gattttaggg acggcttttg ctattacagc tggagccggt acagaaaccg
     4981 cgcttttact aggtttgccg attgctacgt tgacattgat attgaaaaat atttacttag
     5041 ggcttttgat tccaattatg aaccataaag cagacaatta tgcagaagaa ggaaattata
     5101 aaggagtcga gcatatgcac ttgcttgccg gtatcggtct ttccttgatg cttggtgttg
     5161 tggtaatggt ttcttatatg gtgggaagca atacgatcgg aaatctatta aatatgattc
     5221 ctgacttcgt tcaaaagggg ttgtcagtag ctacagggtt gattccagct cttggttttg
     5281 cgatgcttgc tcgtttgctg atcaacaaac aagttgcacc atattttttc ttaggttttg
     5341 ctatagcttc ttacttagag attcctgtga ccggagtagc tatttttggt gcgattttag
     5401 cagttgtggt agtcaatatt atgaatgtcc gtcaactacc acttcaaaca actgcagggg
     5461 aggtagaaga agatgaagaa ttctgagatc aaaaacagca aaataacgaa aaaagagcta
     5521 aatcacgtat tttggcgttc ttttcaaatg gagttttctt ggaattatga acgtcagatg
     5581 aatatggctt atgtttatgc aatgattccg attttgaaaa agttatatca gtcgaaagaa
     5641 gaaatggcag cagctttgaa acggcatcta gagtttttta acacgacccc acatatcgtt
     5701 acactgattt taggaatcac ggctgcaatg gaggaagaaa ataaggatga tcctgaattt
     5761 gatgtgactg cgatcgatag tatcaaaaca tctttgatgg gacctcttgc agggttagga
     5821 gattctttct tttggggaac tttgcgattg attgccacag gtgtgggtac ctctttagcc
     5881 atgcaaggaa atattttagg ccctatcttg ttcattttga ttttcaatat tccgcacatt
     5941 ctgtttcgct atctagcaac aggttgggga tatcgcttag gaacgggttt tttgaaaaag
     6001 atccaggcaa acggtatgat ggaaagtttg acattaggcg cgtctattat tggactgatg
     6061 gtcgttggag caatgactgc cacgatgatc accatcaata ttcctttaaa aatcggttca
     6121 ggagaaaatg ctgtgactgt tcaaagtatt tttgatgata tcgttccaaa tatcttatgt
     6181 cttggagcat ttggcatagt gttttatcta ttgaagaaag aagtgaaacc attaacgatc
     6241 ttgatcggac tagctttctt tggaattttt ggttcgtgga tagggatttt ttaaaaaagg
     6301 agcagagaaa atgtttacga tgcaagatta tatctatgaa gaaaaggaag tactaagtac
     6361 gatcttgaaa aagaatgatt tttcgacaag agaacatatg aaaaaaacag tgaatttact
     6421 gatcttagca acgggttcat cttataacgc ttgtttagca gcgaagccag cattggaatc
     6481 ttatggtgat cttactgtcg atattcaaga acctttttat tttttcaatt atggaaaact
     6541 ttctccttca atcgatactg tgattgctgt gtcacaaagc gggaaaagtg cttctactgt
     6601 tgaagcagta aaaatgatac aaaaacaagg gttacctgtt gttgctatca caaatgacgt
     6661 gcaaagtcca cttgctttag aagctgcaca aattattgat ttaggtgccg gggtagaatc
     6721 agtaggcttc gttacaaaag gctattctgc gactgtttta cagttactac tcttagggat
     6781 aggaattgga ataagtaaaa ataaaatcag caaaaaaata gaacaagact acatgcaaca
     6841 gttgcgcaaa ataatcaacc atttaccagc gattattcaa aaaacggaag aattttttga
     6901 tggatatcaa agtttatttc gtttagcaca gcgtttcgtc accattggat atggtccaaa
     6961 ctggggaaca gctaaagaag cagagacgaa attgactgaa acaatccgcg ttccgtcaca
     7021 aggatttgag ttagaagctt atatgcacgg cccatacctg gaggcagatg cttcgcattt
     7081 gctattcttt attgaagggg aaagtgtaaa taaggaacgt tcgcaaaagt tgcaaagata
     7141 tatgagtcgg tacgttggag agactctcac cattaccaca aaaaaagcaa gaaacgagaa
     7201 aacacttgga ttagcaatag aatgtgatga atatctgtct gtattagcgc ttgtcgttcc
     7261 gtttcaacta ttcgcttata aaaccgcagt agctaaaggt attgacttga acaaaaagat
     7321 ttttgaagac tttgatacag tcttgaaaag taaattataa gaggtggaaa tcatgctgaa
     7381 attcaatgaa gaagaacaaa tcaaagcaat aaaaggcgca ctagctttac gtccgcaagt
     7441 agaagaaatc atcgataaac tttatgcgga aaaatttgac gctgtctatt atctaggaat
     7501 cggtggaacg tatgcttcct cgatgcaagc tgtcacttat atgaatggga aaagcaactt
     7561 gcctgtcttt gtacagcatg ctgcagaata ttacactact ggaaacaaaa gattaacaaa
     7621 agattctatc gttattttgt cctctgttac cggtacaact caagaagtag tgaaagcagt
     7681 agaacaaatc aagaaagtag gagcgacact gattggattt atcgataaag cgaacagtaa
     7741 gttgtctcag ctatgcgatt ttgtggtcac ttatccagct cctggaacag aacaaatcaa
     7801 attttttatg gcagcagatc gattgatgta tttgaatgga gaattcgaag cttattcaga
     7861 atactatgaa cagctcgaac gttatttacc aacagggtta gtggaagcag agaaaaaagc
     7921 agatgcattt ggcttatcat ttgcagaaaa acatcgacgt gatagtatgc attattttat
     7981 tggagcaggg aatcaatggg gagctgttta ttcatatgcc atgtgttact gggaagaaca
     8041 aagctggctt ccatcgaaat ctatccatgc tgccgagttt cttcacggga cgttagagat
     8101 cgtagaagaa acaaccccag tcacattatt tttaggcgaa gatgaacaga gagtgttatc
     8161 tgaacgtgtg gctaaacttt tgccaaaaat ttgcagcaat tatacattga tagacacaaa
     8221 agactatcca gtagaaggta tcagtgaaaa atatcgcgga cgtgttttgt ctttcttatt
     8281 gatgcatgta gtgacacaac gcatcgatgc tcatgtggag cagttgaact gccatccatt
     8341 agagatacgc cgctactatc gtcagtttga ttattaggat agactggata aaaagaatat
     8401 aaaaaataaa gagagcagcg ataactgctc cctttatttt tttaaaatat tggcatcaat
     8461 tacgttataa aacacatttt ttgcattatc tacagttcaa cttataatct gtttaatggg
     8521 acatgtgggt gccaaccatt ttttgttatg caatagtact atttagttgt tgcatggatc
     8581 cgtagtaaaa gtccaagtac aacgagttgc gccagtttac atagcgtttt gtatccagaa
     8641 tgttgactaa aacaaaagtt cctatgtcaa ccgtcaacag agacaatctg tccgttgcag
     8701 gacctgacag atttagaaat gttcaatctg tctcttatgt attttaaatc aatactcact
     8761 aggagaagtt tcctaacctc ctaatagtaa tgctggtagt aacattgtca aaactgcttc
     8821 ctcttaggaa caagcaaagc ataacgagtg taaaaataaa atgtagacta ttgtaacata
     8881 tcattgatta tttcaagtaa
//
LOCUS       DAZKNV010000087         8615 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000087 DAZKNV010000000
VERSION     DAZKNV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.088"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..464
                     /locus_tag="ACG8M1_002530"
     CDS             <1..464
                     /locus_tag="ACG8M1_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423189.1"
                     /translation="NQKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEH
                     IIKHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQ
                     VNANGLVQISGVKGVADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            639..1472
                     /gene="msrA"
                     /locus_tag="ACG8M1_002531"
     CDS             639..1472
                     /gene="msrA"
                     /locus_tag="ACG8M1_002531"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0423190.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            1552..2541
                     /locus_tag="ACG8M1_002532"
     CDS             1552..2541
                     /locus_tag="ACG8M1_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0423191.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            2830..3528
                     /locus_tag="ACG8M1_002533"
     CDS             2830..3528
                     /locus_tag="ACG8M1_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFQ0423192.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            3678..4994
                     /locus_tag="ACG8M1_002534"
     CDS             3678..4994
                     /locus_tag="ACG8M1_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0423193.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            5011..6426
                     /locus_tag="ACG8M1_002535"
     CDS             5011..6426
                     /locus_tag="ACG8M1_002535"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0423194.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            6890..7210
                     /locus_tag="ACG8M1_002536"
     CDS             6890..7210
                     /locus_tag="ACG8M1_002536"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0423195.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            7236..7553
                     /locus_tag="ACG8M1_002537"
     CDS             7236..7553
                     /locus_tag="ACG8M1_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0423196.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            7582..>8615
                     /locus_tag="ACG8M1_002538"
     CDS             7582..>8615
                     /locus_tag="ACG8M1_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0423197.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLV"
BASE COUNT         2862 a         1388 c         1807 g         2558 t
ORIGIN      
        1 tcaatcaaaa aataatttct cagccgggac atattgttgt aaacaaagaa acagtagagg
       61 cgtataccac taaaggaatg gattattttt tatatgatta ttctcctatc gcttcattgg
      121 agaataagga gcatataata aaacacgaag caaagattgg cagtcaatgg gtaaaccttc
      181 cttataaaac aactggtagt tctatcatat atagagtaac taatgagaag agccaagtaa
      241 tcacacttcc tgtatatgct tatttaggaa cgaatgtaga aataaatcat caacctgtaa
      301 aggagcaggt gaatgctaat ggattggtac aaataagcgg agtcaaagga gttgctgata
      361 ttaaagtaag cacaagttat acagtaacga ctattatttc ttatcttgtt acattaactg
      421 catatttatg tttatttttt aaaatagttt tccataaaag gtaaattaac ttttcattta
      481 taaaataaat tgattaaaaa ggagaatctg tcgataagga ttctctcttt tttatacgaa
      541 aaatctgtag ggggatgaag taatcgctta tttcctcact ttatgataaa ttacagctaa
      601 agtcactagc ttgtcttctt cggaaaggag gagaatctat ggatgaggaa caaatattca
      661 ttcaaacact ttataatctg attttgaatc cgaatacacg agattgggaa cgaaaagtat
      721 tgattcagac aaagaatgac ataagagaaa atatatccgt taaagaacag ttatcaaaac
      781 tagaagcaac actacgtcca ttagctatcc gaatgaatct gacgcctgat gtaatggact
      841 tttatttatt gattacggaa ggatttgata aggagcaaaa atatgacttt tccaagcatg
      901 ccatgcaaga tgctgactat caagaacgtg cagtatttgc agggggatgt ttctggtgta
      961 tggtcgagcc gtttgaatcg aaaaaaggga tcctatctgt tttgtcagga tacacgggcg
     1021 gacatgttga aaaaccaaat tatgatcaag taagtggtgg ttacacaggt catgtggaag
     1081 ctgtggagat catttatgac acaagagaaa taagttatag cgagttgctg acaatctatt
     1141 ggcaaattac tgatcccaca gatacatttg gacaatttca agatagaggg aagcaatatc
     1201 gtccagtgat tttttatcaa gtcgaacgac aaaaagaatt agcggaacaa tcaaaacaga
     1261 aactagacag ttcaggaact ttccaccaac caatcgtcac aaaaatcgaa ccagccggta
     1321 cgttttggcc agcagaaaac tatcatcagc aattttacaa aaaacaaccg aaacgttata
     1381 aaaaaatcca gcaagcacgt aatcaatttc tgatctatca acgagtaaaa aacaaatggc
     1441 aaaaaaatat acgaaaaaat cattttgatt aactcctttt ctttaaaatg tagtaaacta
     1501 aaaatagaaa aaagaaagcg ttttaaaaag atttgatgag gaggagaaaa attgtatatt
     1561 gcagatagtg cacgttatga aaaaatggaa tatcgtaaat ccggtcattc aggtttgaaa
     1621 ttaccgattt tatctctcgg attatggcaa aattttggtg attatgatcc tatccataat
     1681 caaagagaga ttttaagagg cgcattcgac atgggaatta cccatttcga ccttgcgaat
     1741 aattatggag gccctgctgg agctgcagag aaaaactttg ggcgtatttt tagagaagat
     1801 tttcaagcct accgtgatga actgattatt tctagcaaag caggttatca tatgtgggaa
     1861 gggccatatg gggaatgggg ctctcgtaaa tccatcattt caagttgtga ccaaagtctc
     1921 caaagaatgg ggctagatta tgttgacatc ttctatcatc atcgcccaga ccctgataca
     1981 cctttggaag aaacagcaga agctttgatg caacttgtaa gacaaggaaa agcattatat
     2041 attggtatat ccaactataa tggagaagat acaaaaaaaa tgactgaaat tttaaaaaga
     2101 aaggaagcac cgttcattat tcatcagatg cgctacaata tgttttctcg tgcactacta
     2161 gaagacgatc tatctccagt attagaagaa gaagggctag gggcaatcac gttcagtccg
     2221 cttgctcaag ggttgctgac aaatcgttat ctacatggta ttcctgaaga ttctagagca
     2281 catcgtaagg aaataccatt cctttcagaa gaacaagttg gatcaactct ggaaaaaatc
     2341 aaagcactgc aaacaatcgc cgtatcacga ggacaatcat tagcgcaaat ggcccttgca
     2401 tggaatttgc gacaaaaatc tgttacaagt gtactggtcg gagcaagtcg gttaagtcag
     2461 ttacaagaaa gtgttcgaat gatggataat ttagatttct caccagaaga agaattgaga
     2521 atcgaccaaa ttctagaata gaaacgatgt aatcaaactt tttatccata tattaaaaaa
     2581 aacaaaagat gacatcaaga atcgaatgaa gatcgtctgt tattgaacat catatttttt
     2641 gtcgttcaaa ataaaaatga tcgaaggcta ggagtgaatt ttatcctagt cttttttatg
     2701 gtaaatatct tcttcgtttg tatgtctatg aacggattaa tcaattttgt atacaaaaaa
     2761 tcatcagatg attcaaacgt gttataataa ttacgaaaaa atacatcaga tgaaaaggag
     2821 gtatgtggtt tggaagaaaa taaaacccta gtagaagtaa ctactgacaa gatccttaga
     2881 tatttaaagg aaatgcagtt gcaagtagga gataaactgc cgaatgaata tgaattgtcc
     2941 gattatttag aggtggggcg aagcacggtg cgagaagctg tgcgggctct agcttccagg
     3001 aatatccttg aagttcggca aggagcgggg acatttgtca gtgataagcg agggattgcc
     3061 aatgacccac tcggtttttc tttgattgaa gatcaggatc ggatgatacg agacttattt
     3121 gaactgagat atttattgga gcctaagatg gcaggtttgg cagcggaata tgcaacgaag
     3181 aatcaaatcg tccaaatgaa aaaattaacg caaaagattg aaacttcttt tcgagaaggc
     3241 acacaagaac atgttcaatt agacatcgat tttcatacga tgattgcaga agctagcgga
     3301 aacgtagcct tgctgcatat tatcccaatc attaatgaat caattgcttt gtttaataaa
     3361 aattatgata tccagcatct gaaaatcgag acgatcgata ttcatacaga gatcgttcag
     3421 gccatcgaaa ggcggaatgc acttgctgcg tttgatgcaa tgactgtcca tatggcaata
     3481 aatcggagag aattacagaa aataatagga gaaaaagaaa ctaattgaca gttcatctga
     3541 tgtattttat gataaataca tcagatgaat ttttgtttta tatttggtaa aaaagaggag
     3601 taaatagttt ctgttcatcg aaatgtaagc gctgactaat agacaaaaag agatgacgtc
     3661 aaggagaaga agcaggaatg aggggatctg gaatgagttt tatggataaa ttagccaatg
     3721 ttttagggaa cgtggcaacg agaatcaata atttaaggta tatcatggtg ataaaaaacg
     3781 catttgctgc attgattccg gtaattatta cgggtgcttt tggcacattg ttttcagcaa
     3841 tggtctttga ctcggaaaat ggcttagcac agataagttt cttgcgtttt ttagaagaat
     3901 taaagcctat cgcatctgcc atcagctatg tcacactaag tttcttgacc atctatgctg
     3961 tttttctgat agggatcgaa ttagccaagc tgaataaagt ggatggtgta ttccctggta
     4021 tcatcgcagt gatgtcttat ttatctgtta atccaactgt ttatgaatta gtgaatgaaa
     4081 atcagactgt tatagtagaa aacgtattgg ctaaacaata tacagatacg aaagggttat
     4141 ttttgggaat gttggtctcc atcctttcta ttgaacttta ttgctggttg aggaaacaga
     4201 agaaactaca gctgagaatg cctgataccg tgccaacgaa tgtttctgct agtttttctg
     4261 ctttattccc gacgattctg actgtatcgg gtatcgcggc tgcgggattt atcatcaaag
     4321 aacttacagg aatgtacctt tatgatatca tttacaatgt cgtacaacgc ccattagaag
     4381 gtgtcgtaca agggttaccg ggtattttgc tattgatgtt tattgcgcaa gtcttttggg
     4441 tgattggtat ccatggaaat caaatggtga agccgatacg ggaaccgttg cttttagcgg
     4501 caattgctgt aaatacggaa gcttttgaag ctggaaaaga agtaccgaac attattacta
     4561 tgccattttg ggatatgtat atgagtatgg gcgggtctgg agtcacgatc ggtttactga
     4621 ttgcagtatt gttagttgga aaacgggaag atatgaaaca aatcaccaag ttatcccttg
     4681 ctcctgggat cttcaacatc aatgaaccag ttatttttgg tatgccgatc atgctgaatc
     4741 caattttagc tattccgttt atcttaacgc ctcttatcac tggaacgatt ggttattttg
     4801 caaccgcttt aggatttgcg gcgaaagcag ttgtaatggt cccttggcca atgccgccga
     4861 tcgtcaatgc ttatctggca acagcaggaa atatcggtgc agttattacg caacttgttt
     4921 gtattattgt ttctattttg atctatctgc catttgtaaa agtagcaaat cgtgtggaaa
     4981 atgatgggat ctaaaaaaca ggaggaaatc atgaaaatta ctattccaaa aaattttatt
     5041 cttggtgctg catcttctgc ttggcaaacg gaaggttgga aaggaaaaaa agaaggacag
     5101 gattcgttta tagatagctg gtataaaaat gaacattttg tttggcataa tgggtatggc
     5161 ccagccgtag caactaattt tatggaacaa taccagcagg atgtggatct gatgaaatcc
     5221 atccatctga cacattatcg gacttctatc aattgggctc gtttttttac tgattatgag
     5281 aactgtatag tagatgaaga atatgctcag catataagtg aaatgatcga ctctttgatc
     5341 gaagcagacg tagaaccgat gatttgtttg gaacattatg aagtcccagc ttttcttttg
     5401 gaaaaatatg atggctggtc ttcaagaaaa gtagttgatt tttatgctaa gtatgctcaa
     5461 attgcctttg atcgttacgg tgatagggta aaaaactggt ttacattcaa cgaaccaatc
     5521 gttccccaaa cgcgttgcta tttggatgct gttcgctggc cgcatgaaca aaacacaaaa
     5581 aagtggatga tgtggaatta tcataaagtt ttagcaacgg ctaaagcagt agagatttac
     5641 cgcagcggaa attatggtgg aaggattggc tgtattttaa atcctgaaat ggtctatgct
     5701 cgatccaatt ctccagaaga ccaaaaagct gcttatatgt atgatttgtt ttataatcga
     5761 gtattttttg atccgatggt aaaaggatac tacacagaag agttcctgga gttgtgtcaa
     5821 aaacaatcga tttatttcga tcctgcaaca gaggatttag aaacgattca gcatcataca
     5881 gtagatttcc ttggaatcaa tcaatattat cctaaacgcg ttcgcgcccc tcgttatcaa
     5941 tggaatgaag agacaccttt ccatcctgaa cgatattatg aagtctttga tttacctggg
     6001 aagaaaatga ataattccag gggatgggaa atctatccga aaatcatgta tgatatagcc
     6061 atgtatctaa aagaaaatta tcataatatc ccttggctga taacagaaaa cggtatggga
     6121 agagaatatg aagaacagta tatggatgag aaaggaatcg tgcaagatga ttaccgtatc
     6181 gaatttatcg gacagcattt gcattacttg atcaaagcaa cagaagaagg cgcaaattgc
     6241 gaaggctata tgttatgggc attcactgac tgtgtgtcac caatgaatgc atttaagaat
     6301 cgatatggat tagttcgaat cgaattgaac gatgaacgaa gcagaacatt gaaaaaatct
     6361 gcttcgtggt atcagacttt gattgataag agagaattgg atttgcctga cgaaatctat
     6421 aaataaatag aagttttttg tagatgttca ttgtatttac tggttatttg aaataaaaga
     6481 ggttgtgaat ccagcgtttt gagctaatac ccagggtcag ctgattgaac accgtttatt
     6541 gagaggttgt gaaaaagctg tcctgcatca agtaataaga atagcaaagt aaaaacaaca
     6601 tcttatgttt ttaacttggt tggacttatt accgcagatg caagcttttg aataccgttt
     6661 atttgaaaaa agttgtgaca agttttgtgt cacaactttt tttgtgcacg ttaaaagaaa
     6721 aaaggtaata aaaattaatt tgtgtgttta gtgtgcgctt tcttttttag tgtgtatgca
     6781 acttggtata gaccttaaat gtgatgatat caacttttta aagcgctttt aaagttggca
     6841 cgctacttgc ttatatacaa gtgtaagtat agaaaggaac gtgtttaaaa tggaaaagaa
     6901 aacaatcatg cttgtatgtt cagctggaat gagtacaagt ctcctagtca caaaaatgca
     6961 aaaggcagca gaagcaaaag gaatggaagc agacatcttt gctgtatctg cttcagatgc
     7021 ggataatcaa ctagaatcta aaaatgtaga cgttttactt ttaggaccgc aagtacgctt
     7081 tatgcaaaat caatttgctg aaaagctagc acctaaaggc attcctttag atgtaatcaa
     7141 tatggctgac tatggcatga tgaatggtga aaaagtactc gaccaagcag aaaaactaat
     7201 aaacaaataa taaaaattat cggaggatac aataaatgga agatcaaaaa aatctagaag
     7261 ccatcatggg tctgatcatg tttggcggaa atgcaaaaag cgatgcaatg gaagcgattg
     7321 ctgctgcgaa aaaaggtgat ttcactttag cagatgaaaa aatcaaagat gcagaggaat
     7381 ctttagtcca agcacatcac tctcaaacag agatgctgac acaagaagca caaggaaatc
     7441 acgttgaagt cacgcttttg acggtccaca gtcaagatca tctgatgaca tctatagctt
     7501 ttacagattt agcaaaagag atcattgatc tgtatcgtcg attgaacgcg taatctacag
     7561 taaagaaaag agggaagatt tatggataaa tttgttgcat ttatggagaa acattttata
     7621 cctgtagcat caaaaattgg tgcacaacgg catttagttg cgattcggga ctcatttatg
     7681 gtgagtatgc cgttaatgat cttaggagca ttagcagtaa tgatcaataa cttaccgatt
     7741 cccgggttcc aagaattgat gaactcaatt tttggtggtg aatcatggaa aggattcggg
     7801 gctgctgctt ggaacggtac atttgccatt ctttctgtct tgattgcttt cttgcttgct
     7861 tatcatttag ctaacggcta ccgaaaagac ggtgtttccg caggtgtgat ttctttaggc
     7921 tctttcttcg ctttaggcgg agcattaggt atgagctcaa acggtttgtt tattgctatt
     7981 attgttggga ttatttcaac agaaatcttt gtacgtttaa gcggaaatga aaaattgatc
     8041 atcaaaatgc ctgatggtgt gccaccggca gttgcaaaag catttgcttc attactacca
     8101 gcaatgatca ctatctctgc gtttgcttta gttgctgcaa tttttgctgc attcggtgtt
     8161 gatgatatcg taggttcttt ctatacagtg gtccaagaac catttatggg acttgcaaac
     8221 tcttatccat ctgccttact gcttgcattt atcacaccat tcttatggtt ctttggttta
     8281 cacggagcga atatggtcga tcctttgatg caaacaatca atgcgccagc cattgaagca
     8341 aacgttaatg caatcgcagc tggacatagc gcaccgttta tcgtgaacaa acctttcttt
     8401 gacagctttg tcaacttagg aggaacaggt gcaactttag gtttactgtt agctatttat
     8461 ttagtaggac gtaaaaacaa accatatatg gttgtaacaa acttgtcgat tgcgccaggt
     8521 gtcttcaata ttaatgaacc aacgatgttt gggttaccta tcgtgttgaa cccgatcatg
     8581 ttcattccat ttattttgac accaatggtc ttagt
//
LOCUS       DAZKNV010000088         8470 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000088 DAZKNV010000000
VERSION     DAZKNV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.089"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            184..333
                     /locus_tag="ACG8M1_002539"
     CDS             184..333
                     /locus_tag="ACG8M1_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFQ0423198.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            344..1858
                     /gene="dltA"
                     /locus_tag="ACG8M1_002540"
     CDS             344..1858
                     /gene="dltA"
                     /locus_tag="ACG8M1_002540"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFQ0423199.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            1855..3060
                     /gene="dltB"
                     /locus_tag="ACG8M1_002541"
     CDS             1855..3060
                     /gene="dltB"
                     /locus_tag="ACG8M1_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFQ0423200.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            3105..3338
                     /gene="dltC"
                     /locus_tag="ACG8M1_002542"
     CDS             3105..3338
                     /gene="dltC"
                     /locus_tag="ACG8M1_002542"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFQ0423201.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            3341..4609
                     /gene="dltD"
                     /locus_tag="ACG8M1_002543"
     CDS             3341..4609
                     /gene="dltD"
                     /locus_tag="ACG8M1_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFQ0423202.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            4750..5832
                     /locus_tag="ACG8M1_002544"
     CDS             4750..5832
                     /locus_tag="ACG8M1_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFQ0423203.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            5832..6635
                     /locus_tag="ACG8M1_002545"
     CDS             5832..6635
                     /locus_tag="ACG8M1_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFQ0423204.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            6705..7445
                     /locus_tag="ACG8M1_002546"
     CDS             6705..7445
                     /locus_tag="ACG8M1_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0423205.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            7456..8460
                     /locus_tag="ACG8M1_002547"
     CDS             7456..8460
                     /locus_tag="ACG8M1_002547"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFQ0423206.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT         2727 a         1390 c         1742 g         2611 t
ORIGIN      
        1 ttttttatat tttttaaaag tacgagaaat tataaagaaa aaagcagtga tttgatgtgc
       61 tatttttata aaagctatgt gacaaaactg ttagtaaaaa aacggtttct gtaagctaga
      121 cacatgtttc tttttgtcaa aattagttac actttgtgtg aggttatatg aggagggaat
      181 ccaatgaaca aatggcgttc taatccaaaa ttgaattatt ggggaaaatt catcattcga
      241 acaatttttt atagtgcagt actgctgttc ctgatttatc tgtatcacta taaaaatatt
      301 caaggaggaa cttttatcta taacgaattt taggaggaag agtatggaaa tcaaaacgat
      361 tattgaagca atcgatgatt ggggaataaa tgaacctgat cgagttgctt atcaggcgga
      421 tgagacgcat acttttggtg aattgaaaca agcatcagac gcacttgctt attatttaga
      481 aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc aatttggagt ttgaaatgat
      541 tgtctcattt ctaggggttg tcaaatctgg ccatgcctat ttgccgattg aagagcatac
      601 acccaaggag cgtatcctat cgatctttcg ggtggctaaa ccatctatgg tcatcagtat
      661 cggggactgg atagaagata ttccttcggt tcctgtcata acaaaaaaag aatttcaaga
      721 aatcaagaag ataccagtag gattttatcc cagaaatagc gtaaaaggta cagaaaattt
      781 ttatattatt tttacttctg gtactactgg agaaccaaaa ggcgtacaaa tcagtcatga
      841 taatctagtc agctttgttc aatggacgat ggaagacttt gggatcaagc ctggtatgca
      901 tttcttagcc caagcgccat tttcttttga tttatcggta ttttctattt atcctgcatt
      961 agtttctggc ggaatgctga agccgttaaa taaagcagtt gttcaagact ttcgtcaatt
     1021 attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt tctactccat catttatgga
     1081 tatttgcttg atggaaccta cattcaatgg agaaaatgtg ccggaattgg acatgttttt
     1141 attttgcgga gaagaattga cgaaaaaaac tgcagaaagt ctacttgatc gattcccaaa
     1201 tgcacggata tataatactt acggtccaac agaagcaact gtagctattt caagtattca
     1261 gattgaccag catgtactag atagttatga ccgactaccg attggctacg taaaaaaaga
     1321 cacgaaagtt tctattgtcc aagaaggtaa acctgtttca aaaggagaaa cgggtgaaat
     1381 cattattgca ggaccaagcg tatcaaaagg ttacctgaac aatcccgaaa agacagctgc
     1441 tgcgttcttt tgtcaaaatg acttagcaag ttaccataca ggggatgcag gtagactaga
     1501 tgaatatggg cttttatttt atgaaggacg tatggatcag caggtcaaat tacatggata
     1561 ccggattgaa ctcggggata tcgaacatta tctgctccaa gacaaccgaa tcaaacaagc
     1621 tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag ctggttgctt ttgtcgtatt
     1681 agaaaacaaa acgaaacagc cggattttca gttgactaaa tctatcaaag aacaattact
     1741 agaagttgta atggattata tgattcctca gaagttccat tatgtcgatc tgctgcctca
     1801 gacagttaat ggaaaaatcg atcgaaaaaa attaacagct gaggtgaatc ctgaatgatg
     1861 ttacctcata tgatccctta tgcagagccg ttttattttt ttcttttagc cattgcgctt
     1921 gtaccgatcg ttctatcttt attgatatgg gaaaaaagat taccagttta tcaatcagca
     1981 gtgacacttt tctttttatt tgtcagcttt ggaggtaatt attggcaaca gggagcggcg
     2041 ctgattgggt atgttttgtg gcagacgata cttgtatggg gctattttgt ttatcggcaa
     2101 aggaaaaatc agacaggatg gttttttgcc gccgttattt tagcgataat tccactgttt
     2161 ttaacgaaag tgactccttt ttttgaacat ggaaaagcat cgttacttgg ttttttagga
     2221 atctcttatt taacctttaa atctgtacaa atgatcatgg aaataagaga tggcatgatc
     2281 aaaacatata agccatttcg ttatatccag tttctgctgt tctttccaac aatctcttct
     2341 ggaccaatcg atcgctatag gagatttgaa aaagatcagc tccatccgcc tgttcgtgat
     2401 aaatatgttg atcttttggg aaaaggcgtc caaaatattt ttgtcggttt tttatataaa
     2461 ttcattatcg gttattattt tggtcaagta ctgcttcctg tagtgggacg cattgcctta
     2521 cagcatggtg gtatttcatg ggcattagta ggttatatgt acgtgtacag tatgtatttg
     2581 ttttttgatt ttgctggcta tagcttattt gcagtcggta caagctacat gatgggatat
     2641 cagacaccaa tcaatttcaa taaacctttt ttatcatgga atatcaaaga attctggaat
     2701 cgttggcata tgacgctgtc cttttggttc cgtgattatg tatatatgcg attgatgttc
     2761 ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa tgtcaaatat cggttatttt
     2821 gctttgtttc ttctaatggg tatatggcat ggattgacgt ggtactacat cgtatatgga
     2881 ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga tccgatttaa gaagaagcat
     2941 aaagagcagt tgccttctaa caaatttacg catggcttag ccgtattttt gacatttcaa
     3001 gcagtatgtt ttagcttcct gattttttca ggatttttag ataaactttt ttttagctaa
     3061 cgaatagtga catattaatt tatataacaa aggagaaaag gaaaatggaa gaacaaattt
     3121 tatcaatctt agaagaaata acaggaacag atgaagtaag aaaaaatcgt gatattgatc
     3181 tatttgatga agggttgctt gattctttag catctgttca attattagtc gagctagacg
     3241 gagagctgga tatccaagtc cctgtatctg aattcgagcg agaggattgg agcacaccga
     3301 ataaaatcat tcaacaagca actgcattga agggttgagt atgaaaaaga aactttttgc
     3361 tattttcggc ccggttgttt tagctgttgg cttactgttt gtgtttttta cctcctccta
     3421 tcaagtagat atctctaatc cagaaacgat tagacgtgcc tcttcttcca tgtcagtgaa
     3481 cgtgttgaaa ggagatgcga taaaaaatta tgcattatct gaaaaacaat atattccttt
     3541 ttttggctca agtgaattaa gcagaatcag tccatttcat ccgtctgttc tggcagaaaa
     3601 ataccagcga aactatcgtc catttttgct gggagcaccc gggacacaat cgttaagcca
     3661 atatatgatg atgcgttctg caggagatgc tatgaaaaac aagaaagtcg tctttattat
     3721 ttctcctcag tggttcgtta aaaatggtgt aaaaactgat tactttaata cgtattattc
     3781 tgaacttcaa acatacgact ggttgttttc aatgaagaaa gtaacgcctg ctgatcgcta
     3841 tttagctaga agattattaa ctttctcaaa agtaaaagag aatgatacgt tgacggcgat
     3901 tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa tctttgaatc agctgcgcag
     3961 ccaatggaac atgctgaaga gagaggatga agtattcagc aatattgggt tgaaagatcg
     4021 acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa caataccaag aaacagaatt
     4081 atccatttta gcaaatcaaa ttggagaacg agaaacgacg aataatccat tcgggttgaa
     4141 aaacgatttt tatacgcatc gtatccgagc ccacgagcca gagctcaaac agtcacaaaa
     4201 aaattgggat tatcgttttt cgccagaatt ttctgatttt cagctggtct tggatcaatt
     4261 agcaaaaaac cataacgaag tattgttcat catcccaccg gttaacgaga aatggagcga
     4321 ttataccgga ctatctcaag aaatgttaca aggatttgcc aaaaagatca aatttcaatt
     4381 aaatagccaa ggattcaatc gaatagctga ttttgtcaat caagcgggta ccaactattt
     4441 tatggaagac acgatccatc taggctggaa aggctggttg gctgcagatc aacagatcag
     4501 accgttttta gaagaaaatc atattactgc tagtaagtat catcttgacg atgctttttt
     4561 tagcaaatct tggcaacatc aaataccaga taaactacaa ttaaaataaa gaaaacaggc
     4621 gagtgttgct cgcttgtttt ctttattttt gaatattctg aataaaagat aaaaatacca
     4681 agtttgcctg aacaaaaatc ataagcaatg gtataatcac aatatgaata tagaaatggg
     4741 ggaaaacatt tggatacaaa agaagaacag ctacttattg atttaacttc tgcaaaagga
     4801 gtacctggaa atgaagaaga ggtaagagaa gtattcagag aatatgccaa accattcgct
     4861 gatgatattt tttatgacgg tttaggcagt gtgattgcca aacatggtgc tggcggaggc
     4921 cccaaggtct ttatttctgg acatatggac gaagttggtt ttatggtaac aaaaataacc
     4981 gaaaaaggat tcttggaatt ccaaactctt ggaggttggt gggggcaagt catgcttgct
     5041 cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc acggtgtgat tggttccaaa
     5101 ccaccacatg ttttaacacc tcaagtaaga aataaacctt atgaaataaa ggatatgttc
     5161 attgatattg gcgcatcaag ccaagaagaa gccaaagagt ggggcatacg tcctggagat
     5221 atggtcactc catatattga atacaaacga atgaatggca gtaaatattt actggcaaaa
     5281 gcatgggata atcgtatcgg gacagctgtt tctctgcgag tattagagaa tctatctaaa
     5341 gaagcacacc caaatgtttt attcgcagga agcgatgtgc aagaagaagt aggcttgcga
     5401 ggtgctcgaa caagtacaca ccttgtaaat cccgatattg cttttgcttt agatactggt
     5461 acagcaggag acactccagg aatgacacca aaagaagcag attcgatttt aggaaaaggc
     5521 ccacagattt tgatttttga tgcatctatg atcccgcata aaaaattatt gaattttgtt
     5581 attgatgtag cagaggaaat ggatattcca ttccaatata cagtgatttc tggcggagga
     5641 actgatgcag gacaaatgca tttgacaaga gatggtgttc cgtctgtagc cattaccgtt
     5701 cctgttcgtt atctgcattc ccatacatca gtgattcatg aagatgatta tttgaataca
     5761 gtgaaactag tcacagaatt agtgaaacgg cttgatagtg aaacagttga aaaaattcgg
     5821 agttatgaat aatgaataat agaataccta tttctgaata tcggaaaaaa gcacgagttt
     5881 ctttggaaaa tcaatgggga atcaatactt ggcttgtttt cttatctata atatttacga
     5941 gcgtcatcca gaactttttt gacggtttca gtccttttcc ggaagaaagc atgcagcagc
     6001 acttattgag ttttctagtc gataatttac ttttattcgc attcaactat gcattgtttt
     6061 acattgcgct agtagttgta cggggtggca gaccaaaaag taacctttta ttttcagttt
     6121 tccaaagaaa gtattttggt tcgatacttg gcatcaattt gatcaattca gtcatcaact
     6181 ggctactcaa cagtttaatc tttctgccca tgtttttaat cagcggagtg agtacttata
     6241 tgcagctgct tttcagttca aatgcggtac ctacgggtgt catgccagaa gattttcttg
     6301 atatcagctt tgttttatcg atgataggga tgatttttgt ttcagcactc atcatgagta
     6361 ttgttggcgg tttattccaa tttgctgcat ggacaaagtt cgactatcct gatttgtcgg
     6421 ttattcaatg tttgaaatat ggctggtttt tattgaaaga tagaattggt acgtatattt
     6481 tgttgcagct gtcttttatc ggctggtatt tgctaggagc aatcgctttg ttcatcggtc
     6541 ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga attttatgaa caagcacgga
     6601 ttgaaaaagg aggtccagac gcctatttta cttagcatgt aagcagttta ttcatcaaaa
     6661 aaataacttt tgtggtagga taaatctttg agggggaatg tacgatgaaa ttaactgttt
     6721 taggatgctt aggagcgtat ccttataaaa atcaagggac aacaggttat ttgcttcaat
     6781 ctgacgggtt caatttgttg atcgatgcag gtagtgctac gctgatcaaa ttacaagaac
     6841 accttgatcc acttgatcta gatgctgtga tccttagcca ttatcatcat gatcatattg
     6901 ctgaccttgg tgtattacag tattactggc aacttcatcc taagagaaat ccggagacat
     6961 tgctttcaat ttatggacac acaaaagatt ccattcactt tgaagaattg acgttggaaa
     7021 atgtctcaaa aggacatcct tattttgaag ctgaagaatt aaaaattggt ccttttctga
     7081 ttacttttat ggaaacaatc catccagtag tatgttacgc catgcgtatc gtagaagaaa
     7141 caacggggaa agtattcgta tttacaggtg attcaggtta tttggaaagt ttcgctgatt
     7201 ttgcgaaaga tgctgatttg tttctagcag atacctatct ttttgaagga aatgaacatc
     7261 atcatgccca tttcacttca aaagaagctg gagaacttgc gaaatcagct aacgtaaaga
     7321 aacttgtact tacacaccta cctcagtttg gtgatttaga acaattgaaa aatgaagcgc
     7381 aaaaggcagc aggcaaaggg attgatatag aacttgctgc agttgacaaa gtgtttaaca
     7441 tttaggagga agaacatgat ttttgtacca aatgaaaacc acgacccaag aatcaattta
     7501 gcaattgaac aatatttgct gcaagaaatg cctttagatg aacctatttt gctcttttat
     7561 atcaatgaac cttcaatcat catcggcaga aaccaaaata cgcttgaaga aatcaatcga
     7621 gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct taagtggagg cggagctgtc
     7681 taccatgatt ttggaaacct gaactttagt tttatcatgc ctgatgatgg ggattcattc
     7741 cgtgactttg cgaaagtaac acagccaatc atccaagcac ttcatgaatt gggtgttgct
     7801 ggggcggaat tgaaaggccg aaatgatcta gtcattgatg gcatgaaatt ttctggcaac
     7861 gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa caattatgtt cgactctgat
     7921 atcaatgaag tagtcaatgc attaaaagta aaaaaagaca aaatcgaatc aaaaggaatc
     7981 aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc ttccagaaga aaagcaaaaa
     8041 atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa ttttcggcgt agagtcagta
     8101 gaagaagtaa aaacgtacga attgactgat gaagattgga aaaaaatcaa tcgaatctct
     8161 gaggaatatt atcgaaattg ggattggaat tacgggaagt ctccagattt caatttctct
     8221 cgccaaaaac gtttttctat cggttcgatt gaagtccatt tgaatgtctc agaaggaatg
     8281 atcaaagaag caaaaatctt tggcgatttc ttcggactag gagatatctc tgacgtggaa
     8341 aaaaaattgg ttggacagaa atatgataaa gcatctctat caaaaatagt cagccaaatt
     8401 gatgtgaaga aatattttgg tgcgatagaa ccagaagaat tgcttacctt actttattga
     8461 aaataaaaaa
//
LOCUS       DAZKNV010000089         8228 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000089 DAZKNV010000000
VERSION     DAZKNV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.090"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="ACG8M1_002548"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="ACG8M1_002548"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFQ0423207.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="ACG8M1_002549"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="ACG8M1_002549"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFQ0423208.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="ACG8M1_002550"
     CDS             2591..3376
                     /locus_tag="ACG8M1_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0423209.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="ACG8M1_002551"
     CDS             3389..4240
                     /locus_tag="ACG8M1_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFQ0423210.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="ACG8M1_002552"
     CDS             complement(4364..4816)
                     /locus_tag="ACG8M1_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423211.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="ACG8M1_002553"
     CDS             complement(5281..5649)
                     /locus_tag="ACG8M1_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFQ0423212.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="ACG8M1_002554"
     CDS             5799..6281
                     /locus_tag="ACG8M1_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFQ0423213.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="ACG8M1_002555"
     CDS             6318..7328
                     /locus_tag="ACG8M1_002555"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFQ0423214.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="ACG8M1_002556"
     CDS             complement(7443..8156)
                     /locus_tag="ACG8M1_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423215.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2440 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtc
//
LOCUS       DAZKNV010000090         8070 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000090 DAZKNV010000000
VERSION     DAZKNV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.092"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACG8M1_002557"
     CDS             476..1339
                     /locus_tag="ACG8M1_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0423216.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACG8M1_002558"
     CDS             complement(1468..3090)
                     /locus_tag="ACG8M1_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0423217.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACG8M1_002559"
     CDS             3339..3860
                     /locus_tag="ACG8M1_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFQ0423218.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG8M1_002560"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG8M1_002560"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFQ0423219.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACG8M1_002561"
     CDS             5941..6759
                     /locus_tag="ACG8M1_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFQ0423220.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACG8M1_002562"
     CDS             complement(6862..7059)
                     /locus_tag="ACG8M1_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423221.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACG8M1_002563"
     CDS             7228..7806
                     /locus_tag="ACG8M1_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFQ0423222.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACG8M1_002564"
     CDS             7901..8038
                     /locus_tag="ACG8M1_002564"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423223.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2408 a         1469 c         1593 g         2600 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt
//
LOCUS       DAZKNV010000091         7720 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000091 DAZKNV010000000
VERSION     DAZKNV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.093"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..222
                     /locus_tag="ACG8M1_002565"
     CDS             <1..222
                     /locus_tag="ACG8M1_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0423224.1"
                     /translation="LKEKFLNLIYDEIAIDPYKGEQKTGDLSGIWSSGFKYAGTTYRV
                     AYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            508..1365
                     /locus_tag="ACG8M1_002566"
     CDS             508..1365
                     /locus_tag="ACG8M1_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0423225.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            1366..1914
                     /locus_tag="ACG8M1_002567"
     CDS             1366..1914
                     /locus_tag="ACG8M1_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423226.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2174..2635
                     /locus_tag="ACG8M1_002568"
     CDS             2174..2635
                     /locus_tag="ACG8M1_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermophilic serine proteinase"
                     /protein_id="HFQ0423227.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRTNESDYNKRDQVLL
                     VKLNEEISVEEAVRTFNASDMVNYAEPNYVVELEPLNDVEEPNTTDSLGNR"
     gene            2679..2765
                     /locus_tag="ACG8M1_002569"
                     /pseudo
     CDS             2679..2765
                     /locus_tag="ACG8M1_002569"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(2731..3801)
                     /locus_tag="ACG8M1_002570"
     CDS             complement(2731..3801)
                     /locus_tag="ACG8M1_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0423228.1"
                     /translation="MKNDIVTYANTKCEEIGISNLEECFFDTNDLSQFLRTGRTNASK
                     LANDLVAKNVLFKINTRPVLFAIKERFEEHFLIPVKDVYESISELKTDLEPNSTDSIL
                     QKMIGYDMSLSDAVEQMKTAVFYPGRGLPMMITGDTGVGKSFFVHTAYQFMKKVNVIH
                     ENAPFKVLNCAQYHNNPELLSGILFGYVKGAFTGADEDRNGLLQDADGGVLFLDEVHR
                     LPPEGQEKLFVYMDGGTYSRVGETIHHASNVRLVFATTEGKEDFLETFMRRIPIHIHI
                     PNIEERGILEKNKLSKILSLAKAKTLARLLMFLLKSLVLHKYSQNILNYYFLEKSKKN
                     RIPNFHLHFQKDLHVDNQFLNQ"
     gene            4403..6247
                     /locus_tag="ACG8M1_002571"
     CDS             4403..6247
                     /locus_tag="ACG8M1_002571"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0423229.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6303..>7720
                     /locus_tag="ACG8M1_002572"
     CDS             6303..>7720
                     /locus_tag="ACG8M1_002572"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0423230.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSF"
BASE COUNT         2617 a         1199 c         1564 g         2340 t
ORIGIN      
        1 ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc atataagggt
       61 gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata tgcgggcaca
      121 acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt gttatgtgga
      181 acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt tgtcgttctt
      241 aagaaggacg gcttcttttt tatcgaaaat ctgattcgtc tacatgacta aagtcgcgag
      301 tattctctgc ttctcgataa attaaataac gtcattactt tgaggaaagc tataaatcaa
      361 tatatttcag cttttcctta tttatgtact accttttact tattaattat aaggtagtac
      421 atatatatct tttttttggt agtaactaaa aataaatatg ttataatagt atcaaatgaa
      481 tattgctaaa agaaaagagg taggaacgtg gtagcgaaga aatatgtaat cggtaatttt
      541 aaaggtggcg taggtaaaag tacgtgcgcg caaatgttag ggtttgaatc agcagttaat
      601 gaaggaaaaa gaaccttgat aattgacttg gatatgcaag gaaatacttc tgatgtgatg
      661 aacttaacgc atatgaactt cactaacgaa gaaggaggcg gagaaggtga accgattgtt
      721 tacgaaaata ctgtgactga cgtgttgata aacaatcttc cacctaaaga ggctgtctat
      781 aaagtaatca ataacctcta tatacttcca gcagacatgt cctttgaaat gtatgatgat
      841 tggatcaaag accaatataa tgattcatta tcccaattca aatatatgaa agaaaagcta
      901 gaaccattat ttgatgagtt tgacgtcatc tatttagatg tcccaccttc tatttctgta
      961 tatagtaaat ccgcgatgta cattgcggat tgggcaatcg tcgtcttaca gacccaagta
     1021 aaatcgatga gaaatgcgat gcaatatctt gagtatatgg acttttttgt gaaagaattt
     1081 gatacaaatt tatatgttgc tggtgttatt cctttcatgt tggaaagcgg tgacgcagta
     1141 gatcaggaaa tgtataaaca agcccaagag atttatgggg aacatttgat taaaaatgtt
     1201 gtactcaaaa atgcgcgctt aaaacgatac gacggatcag gtattacgat ggagaagaca
     1261 aagaaaggtc tcttaaaaca atgggatcgc aaaagccacg aattatttat cagtattttg
     1321 aaagaattgg aagaacacga gaattggtat gcggaggtgg agtaattggc tgacatcaaa
     1381 ggacttgata tttttgggaa caacaaagga ctcgccaaaa taaaaaaaga agcagaagca
     1441 aagaaaaagc agcaagcaat tacaccatct gaaaataagc aattagaagt gcaccaagtt
     1501 caagaaataa aaacttcctc caatgttgaa agacagagta gaggaagaac aaaaaaagtt
     1561 ggcgcaccaa tcagaaagtt tgataaggtt tattccacca agcatccttt aaaactgtcg
     1621 actttgttaa atgcgacttc cagagtttta gtagaaaagt atgagactaa tatgacaaga
     1681 gatgaattgc ttagaaaagc tttagatgag tatattaaac agaatcttac gcaagaagat
     1741 aaacaagatt tgtttaatga cgtggtgaaa gaactagact tgttcagaga aaaatatcca
     1801 attgttccag aattagatga tcgtggagaa ataataagaa ctaccagtca gataaaacaa
     1861 gataccgaag actcactgcg caaagggtgg ggaatgaata ataaagttag ataataatca
     1921 aagaagaact aagtaactac ctttaaacgg tagttactta gttcttcttt gatttgcgtg
     1981 aaatagaggg gatttatttt tctggttacg tgattaaaaa atccaaaaaa tgagcatagg
     2041 aacggttatg attttagggt gtgttttaat gagatattgt gatttcatta ataagtgtat
     2101 gataatctgt tgttgagtta gtaaataagt aatagagcta actctaaaat aaaactatta
     2161 ggaggagatg tagatgaaaa agtttaaaaa gaaaatatat ttaggattgg ttgttggggt
     2221 gagtatgttt gggttcatgg ctcatactaa acaagtaact gcagatacta accaaaaaga
     2281 aaggattatg agccaattag atgactctca aatagagtat gtacccaatg agctaattgt
     2341 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
     2401 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attataataa
     2461 gcgagatcaa gtattattag tgaaattgaa cgaagaaatt agtgtggaag aggcagtaag
     2521 aacatttaat gcttctgata tggtcaatta tgcagagcca aactatgtgg ttgaactaga
     2581 gccgttgaat gatgttgagg agccaaatac aactgattct ttaggaaatc gataacgatc
     2641 ctaattggag taaacaagct aatttaagag agattagcat gccatccgct tgggaagaaa
     2701 ccaagggttc taaggatgtg aaggtagcgg tcattgattc aggaattgat tatcaacatg
     2761 aagatctttc tggaaatgta gatgaaagtt tgggatacga ttttttttac ttttttcaag
     2821 aaaataataa ttcagaatat tctgactata tttatgcaac actagtgact ttaggagaaa
     2881 catcaatagc cttgctaaag tttttgcttt cgctaaagag agtattttcg ataatttgtt
     2941 tttttctaaa atacctcgtt cctcaatatt tgggatatgg atatgtatag ggattcttcg
     3001 cataaaggtt tccagaaaat cctctttgcc ttctgtagtc gcaaaaacta aacgtacatt
     3061 ggaggcgtga tggatagttt caccgactct agaataagtt ccgccatcca tataaacaaa
     3121 tagtttctct tgcccttcag gaggcaatct gtgtacttcg tctaaaaaca gtactccacc
     3181 gtctgcatct tgcaacaatc catttcgatc ttcatctgcg ccggtaaaag cacctttaac
     3241 atagccaaat agtatccccg acaataattc aggattatta tggtattgcg cacaattaag
     3301 tactttaaaa ggagcattct catgaataac gttcactttt ttcataaact gataagcagt
     3361 atgaacaaaa aaactttttc caactccagt atctccagtg atcatcatag gaagccctct
     3421 tccaggatag aagacagcag ttttcatttg ttccaccgca tcggataagc tcatatcata
     3481 cccaatcatc ttttgtagaa tggaatctgt agaattgggc tccaagtctg tttttaattc
     3541 agatatactt tcgtatacat cttttaccgg aatcaaaaag tgctcttcaa agcgctcttt
     3601 gatggcaaat aacactggac gagtattgat tttaaataga acgttctttg caactaagtc
     3661 attggcaagt ttactggcat ttgttcttcc cgttcttaaa aattgcgaca ggtcatttgt
     3721 gtcaaaaaag cactcttcta aattactgat gccaatttct tcacattttg tgtttgcata
     3781 agtcactata tcatttttca tcttataaac agtcctttct aaacttctat cccttaaata
     3841 aatagcaaaa aaaaggaagc aatatcgata tgctgtcctc ttaatttaat aaagcgctaa
     3901 tctaattcac tgtattatca ttttttagta gtatagcaca attatgaatg ccttttcttt
     3961 atatcaaata aagtttatat aaaaaacctc atcctgcaag aaagaaaaaa tgaacccatt
     4021 ctttttatac taggtcttaa aaagacagaa catctgctag aagatagaag agaataagag
     4081 ttatatatgt tggaagatat tcttagaaaa aagacaaaac ttttagaaca cgaaaactat
     4141 attgaacgaa taaaatgaaa aaatgattaa aaaatcattt tattatttac gtttacattc
     4201 taatatgtta aattgaatat aacttaaaca ggcatgtgac tggtaatgca ggcaggacct
     4261 aaataagttg aataacaatg tatgcgtttc aatacacgtt tgccttgttg tcaatttatt
     4321 tagtttctgc ctgttttttg tgttgaggat ggccacttcg actcaaaagt tcatcactca
     4381 aaaaagaaaa gagggaaaca ccatgaatta caaacaaaca gcagaagaag tattgcagta
     4441 catcggtggg gaagaaaaca tatcccattt ggagcattgc tcaactcgtt tacgttttac
     4501 gttaaaagac aacagcaagg taaatatgag ccagttagaa aaagtggatg gcgttatggg
     4561 cgttcgccaa aatgtgcaat gccaagtaat cattggaaac gatgttgttg aagtgtatga
     4621 tgaagtgaaa gcgttattag gtgacaatgt ttcaaatact gaagaagcac caaaacaaaa
     4681 acaaaaatta ggttcagttc tattagattt tattatttct attttccaac ctttaattcc
     4741 tgcgattgca ggtggaggag tattgaagtc cttgttgcta ctagcttcta tcttagggct
     4801 gattagtgac caatctcaaa cctatcagat tttaaatttg gtcggcgggg caccgcttta
     4861 tttcttgcct attctggtgg caatgactac ggctaataaa ttgaaagtca atcaattggt
     4921 tgcagtatct gctgtcggtg cattgatcct tcctgaaatg acagctatgt tggcggaagg
     4981 tgctacattc ttatcttttg gattggataa tatagcgtat gcatctcaag tattcccagc
     5041 catcttaact gttttatttt atgctcaact tgaaaaatgg tttacaaaag tttcaccaaa
     5101 accaattcgt attttctttg tacctatgat gagcttattg attacagttc ctattgcttt
     5161 gttgcttcta ggaccattag gttataatgt aggaacagct ttctcttcta tcattgtgtc
     5221 tttgtacaat caatttggat gggttgcaac cggagtctta gcagctgtac tgccattaat
     5281 ggttgtaacg ggtatgcata aagcaatgat cccttacgct gtttcatcca tgagtgaatt
     5341 gggtgcagaa cttctttatc tcccggcttc attggcacac aatatttcag aagctggcgc
     5401 atgctttgct gtcagtatca aaacaaaaga caaaaaattg aaatctacgg ctgtttctgc
     5461 gggtatatct gcattattcg gaattactga accagctctt tacggggtaa cgattctgca
     5521 caaacgtgtt ttatatgccg ttatgttttc tagcctgatc gggggagcat ttgcaggaat
     5581 cgttgcactt caagcctttg ctttagtggg tcctgggatt gcaagtatca cgatgttcgc
     5641 tgacaaagct gacccaatga atctggtttg ggcatttgca gtatcgggga tttcatttgt
     5701 ggttgctttt gctgcagcgt tggttcttta taaagataaa gaagttgtca atgaagttga
     5761 aactaagatg gaaacggccg ttgtttcaga tgctgttctt tcaagtcccg tgaatggaaa
     5821 agtaatctca ctatcagaag taaaagacac tgttttttct agtggtatgg taggtgatgg
     5881 agtagcaatc attcctgaag aagggatatt agtagctcct gaagatggag aaatcacaat
     5941 ggtatttgaa acgaagcatg ctattggttt aaaaacggct aatggtgcag aacttctttt
     6001 tcatattggt attgatactg ttcagttaga aggaaaaggg tttgaggcat ttgttcgttc
     6061 tggtgaaaaa gtagccaaag gacaaaagct gattgcattt gatattgatt taatcaaaga
     6121 agcaggattc gaccccacag ttatctgtgt ggtaaccaat aaggataatt acactatccg
     6181 ttcatttaac ctagaaaaat tggtaaccaa tgatagtgat ctcttagcta tcagtccgat
     6241 agcttaaaca caagatagtg aaaaaaaata tattgaatga aggaatagag gagaatagaa
     6301 taatgacaaa cacaacaagt tttccaaaag gatttttatg gggcggcgcg atagcagcaa
     6361 atcaagtaga aggtgcttgg aatgtagacg gtaaaggtct ttcagtagcg gatatggcta
     6421 cttataaacc aaatttagac aacaaagatt ttgctgctca tatgcatgtc accctgcagt
     6481 ctataaaaga agctagtgaa gacaaatctg ataaatggta cccaaaaaga aggggcgttg
     6541 atttttatca tcactataaa gaagatttag ctttatttgc cgaaatgggc tttaaaacct
     6601 tgcgcctctc tattgcttgg actcgcttgt tccctacagg agaagagctg gaaccgaatg
     6661 aaaaaggggt tgcattttat gaaaacgtct ttaaagaaat gcaacgttta ggaattgagc
     6721 cgattgtgac actatctcat tatgaaatgc cattagcttt agcagttaaa tataatggct
     6781 gggtggagcg tcgagtaatt gatgattttg ttcgcttcgc taacgtttgt tttgatcgct
     6841 tcggcaaata cgtaaaatat tggctgacat ttaatgagat agacagcatc caccgtcatc
     6901 catttacaac agctggaatt atccaagaga aaagcgcaga aggtcaagaa gctcaagata
     6961 tctatcaagc attgcatcat caatttgttg cgagtgcgtt agtgacaaaa gatgctcatg
     7021 aaaaaattcc aggaagccaa gttggttgta tgttaacgaa attgatgact tatccattaa
     7081 cttgcgcacc agaagacgtt gagctgacct tgaaaaagaa cttagaaaat aatttttatg
     7141 cagatgttca agttaaggga gaatatcctg ctctaatcga aaaggatttg gaaaatcggg
     7201 gaattcagat taaaatggaa gatgaagatc gagaaatttt aaagaaacat accgtagatt
     7261 ttgtttcttt cagctattac atgtccatgg cagaatcagc tgatccaaac gcagaacgca
     7321 caccgggaaa tactgtttta ggggttaaga atcctcattt gccttcaaca gattggggct
     7381 ggcaaatcga tccaaaaggt ttgaaaattt cgttgatcga actttatgat cgttaccaag
     7441 taccgttgat gattgtggaa aatggtatgg gagcagtcga tcaggtagta gatggtaaaa
     7501 tccatgatcc gtaccgcatc gactacttta aagcacactt ccaacaaatg aaagaagcaa
     7561 tcgatgaagg tgtagatttg atagcttata ctagctgggg accaattgat ttagttagtg
     7621 caggaacttc tcaaatgtct aaacgatatg gatttattta tgtggatgca gacgatgaag
     7681 gaaatgggac atataaccgc ttgaaaaagg attcgttcaa
//
LOCUS       DAZKNV010000092         7640 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000092 DAZKNV010000000
VERSION     DAZKNV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.094"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            92..1519
                     /locus_tag="ACG8M1_002573"
     CDS             92..1519
                     /locus_tag="ACG8M1_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423231.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1611..1976)
                     /locus_tag="ACG8M1_002574"
     CDS             complement(1611..1976)
                     /locus_tag="ACG8M1_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFQ0423232.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1973..2338)
                     /locus_tag="ACG8M1_002575"
     CDS             complement(1973..2338)
                     /locus_tag="ACG8M1_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFQ0423233.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2530..2778)
                     /locus_tag="ACG8M1_002576"
     CDS             complement(2530..2778)
                     /locus_tag="ACG8M1_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423234.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2777..2905
                     /locus_tag="ACG8M1_002577"
     CDS             2777..2905
                     /locus_tag="ACG8M1_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFQ0423235.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2962..4656
                     /locus_tag="ACG8M1_002578"
     CDS             2962..4656
                     /locus_tag="ACG8M1_002578"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFQ0423236.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4756..4929
                     /locus_tag="ACG8M1_002579"
     CDS             4756..4929
                     /locus_tag="ACG8M1_002579"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423237.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5307..6440
                     /locus_tag="ACG8M1_002580"
     CDS             5307..6440
                     /locus_tag="ACG8M1_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFQ0423238.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6471..6791
                     /locus_tag="ACG8M1_002581"
     CDS             6471..6791
                     /locus_tag="ACG8M1_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFQ0423239.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6820..7284)
                     /locus_tag="ACG8M1_002582"
     CDS             complement(6820..7284)
                     /locus_tag="ACG8M1_002582"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0423240.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7417..>7640)
                     /locus_tag="ACG8M1_002583"
     CDS             complement(7417..>7640)
                     /locus_tag="ACG8M1_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0423241.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         2502 a         1471 c         1374 g         2293 t
ORIGIN      
        1 ctttttcaga aattaactga tgatttcaaa aagaaaacat gtcataatat ttcccatatt
       61 gtgcaaaaaa atacaaggcg gaggctctac tatgattgaa gaatatattg agaaaaatat
      121 tttaagacag ctgtttttat gtgggcaatt ctatgtaaat aaagaagtca atctagaaaa
      181 gctctccaat ctcctgcatg tttgcaaaac cactttactc aatgatatca ataacataaa
      241 aaaagaattt gaagaacaga tcgcttatac acatcgggaa aaggaccgtt acactttata
      301 tttttcagaa catatacctc gatgcaagat catgcagcaa ttgtctcaaa attcgttgtt
      361 tttaaaaact tgtctgcttt atttggaaga agatgaacct gattatcttc aattaactga
      421 atgtgaattc atctctgtca gcaaagctta ttcattaaaa aaacaagtat tagcttattt
      481 taatgactgc gggatcgaaa tcgaccgcta ctcccctcga ttcactgaaa tggaaagacg
      541 tctgctgctt cttaatgtgt cgtatcgttt aggcggtttt aattcttggg agctacctga
      601 atcgtttttt gaacgtgccg atcgtttcat tgaatccgta acggaaaata gtggcagatt
      661 ttatgataaa gaaaataaag aaatcttatc gattggtttt gctatcagtt tcctacgcca
      721 gcaagtgtgt gctgtgacaa tagattcaaa atttatcgaa gaaatcaaaa aacgtcctat
      781 ttacaattat gtcgaatcag catgggaaaa cactgatttc caaacctatt ataaaaaaga
      841 agaattcgcc tttattttga cactattcaa tctttgtaat tatggtttcc attcttatca
      901 gttgattgcg gaagactttc aacagctaca ccaagtgttt attgacaata ctcccgaaat
      961 aaaagaacta gttgctacct ttgaatctca cttcaatcaa gaattattcg gaaaccaacc
     1021 gttcgaacgt gcgctgattc atctgatgcg ttcggcttgg gataactatc aattattcat
     1081 gccagaaaaa ttttatcttt taaatgagga acagacaaat ttatataaag aagtccagac
     1141 aattttttcc agctggtcca gccagttacc ttatgatcta cggttgaatc ctaattgcat
     1201 gcgggctttt gtgatcgaat tgagcggaat tctccgtctg acaaaagaac atctgactat
     1261 ctatatcgtc acaaattcgg atgttcatta tctgatttat cgggaagcct tggaagctgt
     1321 aactactttc gattttcaag ttgcaccaac aatttattca agtatatctg atataaagaa
     1381 gtatgcgcag cagtcctcaa accgggtatt atgtgaacgt acattatata caccagatgc
     1441 ggtccaatat gaaaatatta ttcctatttc gatcaatacg atcgatcgag ctatcatttc
     1501 agctgtgcaa aacaaataag gggctgtgac aaaaatcatg tcacagcctc ttatttgttg
     1561 aagatgccca tttctgtaac aatctcttga tacacgtcag gctcacaacc tcacttattt
     1621 tggacatcta cgggtccgat ctctttattt aaaaaataag aaatgatggt tcggataact
     1681 accaacgccg ctagttggaa aatatcctgc aaggtaggtt tgataatcga ttcgatgatc
     1741 ccagctgaaa caagaatttc caaacttaga agtatatagc ctcccaacat ctttttaata
     1801 gcattgttct cgctgactcg gtcgctttgc acttttgtat ggacaaataa atatttcaaa
     1861 aaatccttga ttgatagaca aacaccccaa accaataaac agatagcaaa gatatcaagt
     1921 cccagtacaa gtttttcgaa atatggaaga agaaactgca tcaactctgt cgtcatccta
     1981 cctctcctct tctttgtttt tctttgtctt ctatttcctg attcaagaaa taagaaatga
     2041 ctgttcgaat gataataata agtgcaagct tcaaaatatc tgtccaagtc ggcttgataa
     2101 ctgactcgat gatatcagca acgactagta cttccaagct taacaaaata taacttgcta
     2161 gcagttttct tgtatctgca ttacgagtat tacgttctgc atagtttttc ttgacatgag
     2221 accaatcaaa aagtttgaat agaacaagaa cgatcccgac aattaagata ccgatagaac
     2281 aaatatttaa aatagcaatg atccattcta gaaattcaat taaatttgag cgaaacatat
     2341 acgctaccta ctttctttta atttgttcct attcttttat tgtaaaagaa agttaccttg
     2401 ttcgtctatt taaaagttgt tctaatgata acggttcgct taaatttttc tttttcactc
     2461 tcccattttt ctccctccat ccataaatcg tggaagtatc caaaacaacg tagcaagtta
     2521 aaataaggct tagtccgtca tcagcttttc aaagaagcac tgtctcggtg ctttttttgt
     2581 acccaaattt ctaaaaatag aaccatacac ctcctcaaat cttttcttct tacctaccct
     2641 atttttattt acaggaaaat cagacacttc ttcttttttg tcaaaatttc ctttttcttc
     2701 tcgtcctatc atttggcatt ctaataaaaa cgaactatcc ttggatatag aaagagaaaa
     2761 caaggaggcg tttttcatga gtaaaaaatt aatcaaagtc ggcatcggtt taggtttgct
     2821 tgcccttggc gctgcatatc taggaaaaaa gacaggacta ttcgaagatg acagtcattt
     2881 atatgatgaa ttcgaatcaa tctagcatcc tatttagttg aatcactacg gacatacttg
     2941 gaagacattg gaggaatcac aatgagaaaa agtaaagcaa taatgattgg tgccggtatt
     3001 gccaatatgg cagcggctgt ttatttgatt caagaaggca aatggaaagg ggatcagatc
     3061 accttttatt cattggatga tcacggttca aatgatggtg caccgaccga cactgtagtg
     3121 gatgaatatt ggaataaaaa ccatccatta gaaaaccaaa aaggctatat tgctcgaggc
     3181 ggtcgcatgc ttaattaccg tacctatgta gatttgatgg atctgttaag tcgaatacct
     3241 tctgttactg agccagggat gactgctgaa gaagatacga gagattttga tgcaaaacac
     3301 cgaacctttg acaaagcacg tttgatggaa ggtggcaaag gaatcattga tggcggaaaa
     3361 ctgggattca ataataaaga ccgtattctt ctgactaaac tgattgctat gcctgattca
     3421 gaagaagaaa aactagacaa tatcactatc gaagaatatt tcaaagatga tccacacttt
     3481 tttgaaacaa acttctggtt tatgtgggaa acaacatttg ctttcagaac acgtagttct
     3541 gctcaagaat tgcgtcgcta tatgcatcaa atgatttatg aattcactca aatcgaacat
     3601 ctagtgggcg tcaatcgaac acgttacaat caatacgaaa gtattatgct tcctttgatc
     3661 gagtacttga aagaacaagg atgcaaaatc attttgaacc gccgtgtcac tgactgggaa
     3721 ttcaaagaaa caccgatgca agatgaaatc actgtgactg gtttgaaaat taccaataca
     3781 ctgactcaag aagaagaata cgttgtggtc gatgaagata cagcagttat tttcactaat
     3841 gggtccatta cagattcagc tactttagga gattacgaaa caccagctgt agaaaatatg
     3901 gattatggtg cagcttctag tctctggaaa aaagccagtg aacgtttcta caacttggga
     3961 aatcctgaca aattctttgc tgatcgagat gcaagcgaat gggtcagctt taccctgacg
     4021 acgaaaaacc atttgttgtt gaatgaaatc acccgtatca cgactcaaga accaggaaat
     4081 gccttgaatt catttatttc aaccacaccg atcacgccgt taggccaaaa agatgtcaat
     4141 atgtctattg tcgtgcatca tcaaccgcat tttacgtctc agaaaccaaa tgaaacagtt
     4201 atttggggtt atttccttta tccaagacga cgtggcgaat ttgtggataa acagtatatt
     4261 aaaatgaatg gaaaagaaat gctagaagaa ctgattggac aactttcaaa agtagatcct
     4321 ggaccagtga atattcgtga aaaagaaaca gaaattttcg acagcgtaat aaataatatc
     4381 cctgtctata tgccttatgc ttccgcgttg ttcaataatc gtgccaaaag cgatcgacca
     4441 aaagtcattc ctaaacattc gaccaatctg gcctttacag gagaatttgt cgagcagcct
     4501 tatcagatga tctttactga acaaagtgct gtacgttctg gagaaatcgc tgctttccat
     4561 tttgcgggta ttcctatgtc ccgtcttgtc aaaacaccgc gttacgacaa agatattcct
     4621 actctagctc gtgccgcaaa aaaaatgttt gaataatcaa gaggttgtga aaaagctgcc
     4681 ctgcatcaag taataagaac aaccaggcta aaacagcttc ttatgttttt gatttggttg
     4741 gacttattac cgcagatgca agcttttgaa caccgtttac caagaggtta tgaaaaagct
     4801 gccctgcatc aagtaataag agcagccaag ctaaaacagc ttcttatgtt tttgacttgg
     4861 ttagacttat taccgcagat gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa
     4921 ggcgtttagt ttcgagtatg aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat
     4981 aaatttgact taataccgag aaactgatcc cttctgtcat aacctctttt tatttatgtc
     5041 tgtttctttt tgaaaacaac tattttttca acgtttactc tcttgccaat ccaacatcat
     5101 ctaacggata caactatttc aatgattacc attacactaa aaaatcggaa acacacctct
     5161 ccgaacacaa atacataaga ctatagaatg tttcatttaa gaaaaaaagc gtttcattat
     5221 caaaaaggta agatctcctt taaaatgaaa ttatctgtag tactaataat gcagacaatt
     5281 ttatgaatct gaaaggagca tctccaatga aagcagtcac ttggcaagga aaacagaaaa
     5341 tggaaatcag aaacgtagat gatccaaaaa tattagaacc aacagatgca atcatccgta
     5401 tcacagcaac agccatttgc ggctccgatc tgcatcttta ccatcatggt gaagcagttt
     5461 tggaaaaagg gtatgttgta ggacacgaac caatgggaat cgttgaagaa gtgggatctc
     5521 aagttcaaac attgaaaaaa gggcaacgtg tggttatccc ttttaatatt agttgtggtc
     5581 attgtcattt ctgcctgaat cacatggaaa gccaatgtga tgaatcaaat ccagatcagt
     5641 tatatggcgg gcttttcgga tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg
     5701 aatatctaag agttccttat gcagactcta cttcatttgt tgtaccagat aatgatcttc
     5761 ctgatgaaaa agttttattt ctatcagata ttttgcccac agcttattgg agcgttgaaa
     5821 acgcaggagt aaaaaaaggc gatacagttg tgattctagg ttctggtcca gtcggtctat
     5881 tcgctcaaaa attcgctgtt atggctggag cagagcgcgt aatcgcagta gatccagtac
     5941 agcaccgtct agataaagcg gctaattaca atggggttga aacttatttc ttagaagaca
     6001 cggcacaagc tggaacagaa ttgtatgaac tggctaaagg tggcgcagat gtcattatcg
     6061 attgtgtagg aatggacgga ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct
     6121 tacaaagcgg cacaatctct ccattacaga tggcatcgca agctgtcaaa aaatttggaa
     6181 cagtccaagt aactggtgtt tatatgactc cagcttcttc ttacccgctg caagaatttt
     6241 ttatgcggga tatcgctgtc aagcatggac aggcaccaat tatccatcta atgccaaaaa
     6301 tttacgcaat gattgcagaa ggactattcg atcctacaca aatcattact cattcgctgc
     6361 cactatcaga agcagcacaa gcatatgaga tctttgacaa aaaagaagat aaaaatataa
     6421 aagttgtttt gaaaccttga attcagtaaa aaatacaggt gattttcttt atgcccaaaa
     6481 tcaaacgaaa tacccatgag atcgaaatag gaaaagaaga agatatcgaa atacgaggac
     6541 gtcgcttccg cttctatttc caaaatcgtt acacattgat ctcactggct gtcgatttat
     6601 taaccgggat tttctatatt tttggaagcc ttgcttcctt aactaaaatc cccgatcgat
     6661 atggcaccta tttttatttg gctggtgcta ttttcttgac gattcgtcct attctcagaa
     6721 tcgtaaggaa catttttatt tacgacgaaa aaaaagcaat gaagagaaca agcaaaaaaa
     6781 aagaggcatg agaatttttc aaatctcatg cctctttttt caccctatcg tatcactttg
     6841 atacagacga gcggtcgtcc cactttcttc cttgaccatt gtcaaaaatg tccactcgta
     6901 tcgttcataa aacgtggtat gatctgtaat taagtaaagt ttttcgtacc caagttgatg
     6961 catttctttt ctgatttccg ctaatatccg cttggctatc ccctgcttac gcttttccgg
     7021 ttcaacaaac agggcacaaa gatttggtgt cagatcaggg cggttatgga agtcgttttc
     7081 aatgacgccc gctcctccga cgatggtttc tttttcatct aagaccacat accattgagg
     7141 aatactttcc ttattagcga ttccagtacg aatactttcc tcatacacaa cagcaggaac
     7201 tccccatttt gatgaaaacc aattcgcgct ttgttttact aattctgggt gttctcttaa
     7261 tttgatccag ttatatgtaa ccaatgttta aacctccgac taaaataaaa cgtttacaaa
     7321 aattatacaa gtctttatga aaattagcaa tgacaacaat agtgatgtaa aaaaaaaaaa
     7381 cggaaaacaa tcacttgttc tccgtttttt gattaatcaa gcatctaaag cttcttttct
     7441 tctttcttgg atcgtagcta ccttgacgaa cggtagatag atcaaaatag aaagaaccaa
     7501 attgacagcg gctagtacac cacctgcaat actttttgtt gccaatacac cgccaataat
     7561 tggtggagtt acccatggag gcataacggt agctgctggc actaaacctg tagaagtcgc
     7621 aaagtaagca acactaacta
//
LOCUS       DAZKNV010000093         7484 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000093 DAZKNV010000000
VERSION     DAZKNV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.095"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(94..1392)
                     /gene="eno"
                     /locus_tag="ACG8M1_002584"
     CDS             complement(94..1392)
                     /gene="eno"
                     /locus_tag="ACG8M1_002584"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFQ0423242.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(1508..2263)
                     /gene="tpiA"
                     /locus_tag="ACG8M1_002585"
     CDS             complement(1508..2263)
                     /gene="tpiA"
                     /locus_tag="ACG8M1_002585"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFQ0423243.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(2367..3557)
                     /gene="pgk"
                     /locus_tag="ACG8M1_002586"
     CDS             complement(2367..3557)
                     /gene="pgk"
                     /locus_tag="ACG8M1_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFQ0423244.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(3667..4668)
                     /gene="gap"
                     /locus_tag="ACG8M1_002587"
     CDS             complement(3667..4668)
                     /gene="gap"
                     /locus_tag="ACG8M1_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFQ0423245.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(4709..5800)
                     /locus_tag="ACG8M1_002588"
     CDS             complement(4709..5800)
                     /locus_tag="ACG8M1_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFQ0423246.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(5949..7283)
                     /gene="rpoN"
                     /locus_tag="ACG8M1_002589"
     CDS             complement(5949..7283)
                     /gene="rpoN"
                     /locus_tag="ACG8M1_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFQ0423247.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            7343..7414
                     /locus_tag="ACG8M1_002590"
     tRNA            7343..7414
                     /locus_tag="ACG8M1_002590"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7376..7378,aa:Arg,seq:ccg)
BASE COUNT         1936 a         1581 c         1384 g         2583 t
ORIGIN      
        1 atatttcagc aagtagagag ttcgattact taactaagtg atcatactcg actatctttc
       61 aatagtcgat catgtatctt cattagaaaa gaattatttg ttttttaagt tgtagaaaga
      121 tttcaaacct ttgtattctg caacttcacc aagttggtct tcgatacgta gtaattggtt
      181 gtatttagca atacggtcag tacgtgatag agaaccagtt ttgatttggc cagcgtttgt
      241 tgcaacagcg atatcagaga ttgttgaatc ttctgtttca ccagaacggt gagatacaac
      301 tgctgtgtag ccagcttctt tagccatttc gatagcttcg aaagtttctg ttaatgtacc
      361 gatttggttc actttgataa ggattgagtt agcaattcct ttttcgatac cttcagataa
      421 tttttgagtg tttgttacga acaagtcgtc accaactaat tgaactttgt cgcctaatac
      481 gtcagttaat ttcttgaatc cgtcccagtc gttttcgtct aatccatctt cgattgagat
      541 gattggatat ttagaaacta attcttcgta gaatttgatc atttcgtcag ttgttttttc
      601 gccttcgcct gagtcagcta gtacgtaaac acctttttct ttgtcgtaga attctgaaga
      661 agcagcatcc atagcaagaa caacgtcttt accaggtaca tagccagctt tttcgattgc
      721 ttcgatgatt acttcaaaac cttcttcgtt tgaaccaagg tttggagcaa atccaccttc
      781 gtcaccaaca gaagttgcta atccgcgagc tttcaagatt gaagctaatg cgtggaatac
      841 ttcagcaccc atacgtagag cttctttgaa tgttggagcg ccaacaggca tgatcatgaa
      901 ttcttggaag tcgattgagt tatcagcatg tgatccgccg ttgatgatgt tcatcattgg
      961 tgttggcaat acttttgtgt tgaatccgcc taggtagtgg tataaaggta cttctaggta
     1021 gtcagcagct gcacgtgcaa cagcgataga aacacctaaa atagcgttcg cacctaattt
     1081 acctttgtta ggagttccgt ctaaagcgat catagctttg tcgatagcca tttggtcacg
     1141 aacatcgtag ccaatgattg cttcagcaat gatgttgttt acgttgtcga cagctttagt
     1201 tacaccttta ccgccataac gagctttgtc tccgtcacgt aattcaactg cttcgtattc
     1261 accagttgaa gcacctgaag gaaccattcc gcggccaaaa gctccgcttt ctgtgtatac
     1321 ttctacttcg attgttgggt taccacgtga gtctaagatc tcgcgagcgt aaacatcagt
     1381 aataattgac atgttttgtc tctcctttga gtttgttttt tcctaaggga tttccctcat
     1441 atacgatttt agttaatttt gctcattagt gcaaacattt cttgcatttt tcgcaaattt
     1501 tcaacaatta ttttacagcg tctaacaatg acaagaatga atctgcttgc aagcttgcgc
     1561 caccgactaa agcaccgtca acattttctt ttgccatgta ttcagcaata ttttctggtt
     1621 ttacagaacc gccgtattgg atacgaactg cttctgatac ttcttttcca taaagttttt
     1681 caactgtttg acgtacaact ccacaaattt cgtcagcgat ttgtgcgtca gctgatttac
     1741 cagtaccgat tgcccagatt ggttcataag caataaccat gtttgacacc tgttcagctg
     1801 aaagatcagc taaaccagct gtaatttgtc cttcgatcca ttcagcagtt ttgcctgctt
     1861 cataggtttc taaagattcg ccgcagcata ggattggtgt cataccattt gcaaagatag
     1921 ctttcgcttt tttattgatg tcttcgtctg tttcatggaa atattcacga cgttctgaat
     1981 gtccgatgat cacataatga acacctagat cagcaagagc tgctggtgaa gtttcaccag
     2041 tgaacgcacc tgagttttcc cagtagcagt tttgtgctga gatttttagt tctgtacctt
     2101 cagctgatgt cattaattct tgtaagaata atgcaggaga tccgatgact gaatcaactt
     2161 tgtcatttga agggattttg ttttttactg cttcagcaaa ttcttttgct tctgatgcag
     2221 ttttgttcat tttccagtta cctgcgataa taggtttacg cattgaggaa cacactcctt
     2281 aatttattga aaaatggcta gggagtcatg aaaactccct tcaccttttg ttcgattact
     2341 cgtcagaatt gagcaaactt ggtcgtttat ttatcgttga ttgctgctag tcctggtaat
     2401 tctttacctt caagcaattc caagcttgcg ccgccacctg ttgagatgtg tgtgaatttg
     2461 tcagcaaatc ctaattgttc tgctgctgcg gctgagtctc cgccaccgat gattgttgtt
     2521 gcgccttcta agttagcgat tgcttcacaa acaccgattg tacctttagc aaagttactc
     2581 atttcaaata cacccatagg tccgttccaa acaactgttt ttgcaccttg taatgtatca
     2641 gcaaataatt ttactgatgc tgggccgatg tctaaagcca tcaaaccatc aggaatgtct
     2701 ccttcgatta cttgtgtttc aacatcattt gaaaattctg gtgcacagac attgtcgatt
     2761 ggcaagacaa gtttgtcgcc tgctttttcg attaattctt ttgctagttc cactttatca
     2821 gcttctacta gagagttacc gatcttgatt ccttttgctt cgtagaatgt gtaagtcatt
     2881 ccgccaccga tcaagatttt atctgcttta ggaatcaagt tttcgattac gccgatttta
     2941 tcagaaactt ttgcgccacc aaggattgca atcattggtc gttttggttc ttctactgct
     3001 tcaccgatga acttgatttc tttttccatc aagaatccag caactgttgg gataccagtt
     3061 gaagcgatac ctacgttaga agcatgtgca cggtgagctg taccgaaagc atcgttaaca
     3121 aatacatcgc ctaatgaagc ccagtattta cctagttctg tatcattttt gctttctttt
     3181 ttaccgtcaa tatcttcaaa tcgtgtattt tcgaatacga caacgtcgcc gtcattcatg
     3241 ttgcggattg cttcttctaa ttgttctccg cgagtttcag gtacgaatgt tacttcttta
     3301 cctaataatt cgcctagacg ttttgcaact ggagctaaag attttccttc tttatcttct
     3361 tctgttttta cacgtccaag gtgagagaaa aggattgctt ttccgccttg ttctagaacg
     3421 tagttgattg ttggcaatgc tgctttgata cgagtgtcgt cagtgatcac gccgtctttc
     3481 aaaggaacgt tgaagtcaac acggacaaga acttttttgt cttttaaatc gatatctttc
     3541 actgttttct tagccatttt atttcctcct gaataaactt attatcaaaa aaagcggaag
     3601 aagcgcgatt gcttccccgc ttttaaatgt acatgtctat aatttacact tgtacgtttg
     3661 tctatcttat aagttagcga agtattctaa agtacgtact aattgtgcag tgtatgacat
     3721 ttcgttgtcg taccaagcaa cagttttaac taattgtttg tcgccaactg tcattacttt
     3781 agtttgtgta gcatcaaata atgaaccgta agtcatacca acgatatctg aagaaacgat
     3841 ttcgtctgtg ttgtatccgt aagattcgtt tgaagcttct ttcattgctg cattgatttc
     3901 gtcaacagtt acttcttttt caagaactgt tactaattct gttaatgaac ctgttggtac
     3961 aggaacacgt tgagcagctc cgtctaattt accgttcaat tcgggaatta ctaaaccgat
     4021 agctttagca gcacctgttg agttaggaac gatgtttgca gcagcagcgc gtgcacggcg
     4081 gaagtcacct ttaggatgag gtccgtctag agtcatttgg tcacctgtgt aagcgtggat
     4141 agttgtcatt aatccttcaa caacaccaaa tttgtcgttc aatgttttag ccataggagc
     4201 taaacagtta gtagtacatg aagcacctga gataactgtt tctttaccag ttaatgtttc
     4261 gtggtttgtg ttataaacga ttgttggaac atcgtttccg ccaggagcag agataacaac
     4321 gcgtttagca ccagctgtta aatgtttttc agctgctgat ttagaagtga agaaaccagt
     4381 acattctaga acgatatcta cgcctagttc gccccatggt aattcttctg ggttgcggtt
     4441 agctaatact ttaacttctt ttccgtttac gttgaatgaa ccttcatgaa cttcaactgt
     4501 tccgttgaaa cgtccttgag ttgtgtcgta ttttaacaag tgtgccaaca ttttagcatc
     4561 tgtcaagtcg ttgattgcta ctacttcgat tccatctaca tcttggatac gacggaatgc
     4621 tagacgtcca atacgtccaa aaccattaat acctacttta actgtcattt aagatttcct
     4681 ccttatgaaa atcaaaaaaa tatttatttt aaagggttac cccttttaaa atctcatttg
     4741 cagcagcttc atcagtgatg agccacgttt gttttggtgc atttttcata taagctcgaa
     4801 ttgctttagc ttttgatttt ccgcccgcga ttgccatgat gatcgggact ttttccaaat
     4861 cttgcaattc tatgccgatt ctagggacct tataaacgac ttcacctttt tcattgaaaa
     4921 agtagccaaa agattccgca acagcatttg cttgtttcag catgactaat tctttttcag
     4981 tcatcttacg acgtgctgcc atgtgtaatg cacgcccaat actatgaata acacaattcg
     5041 cttcactaat caagtttaag acttcttgga tagatggctc attgagtaaa gaattgtaag
     5101 ttgccagact taattgttcc ggaacataaa gtgcgcggtg gttaccgttt gctttagcag
     5161 ccattcttgc actgacagaa tttgcctgta cagttatcgc ttcaccaatc ccgcctcttg
     5221 cagggacaaa caggttatgc cgtttcttat tttccagatt agacaattgt tcggctacca
     5281 cagccatagt agttcctccc atcacagcga tgatattctc gccttctgga agtagtcggt
     5341 ctaaggcttc gctcagcgct tcgccgaatg catcagccac tttggtctgc tcttcgctgt
     5401 ttcctgaaac aacgatacag cgttggttac caaaatattc tgccaactgt tgttcggttt
     5461 gatgcgtacc taaaagctga tccatgaagt tttcaaggct ttgataaact tcttcgccct
     5521 tagttgtcag cgtcataccg ctttttgagg tgtcgatcaa attcagattt ttcaaaaggt
     5581 ctgtttctgt tcgtaagact cgttctgtga tccccatact ttccgataaa cttcgacgcc
     5641 caatcggctg catccaatag atatttcgta aaattttata gcgttcttgc aacacttcga
     5701 taatatctgg tgcaacagat tcaatcattt ttatttcatc cagcatagcg atctccttag
     5761 ttggacactt tacgtccaat gtagacttaa aacgacccat atacgataaa aaaagaaatt
     5821 aactattcga atttcacatc aataaaggga aatctcaacc tcacgactgt aagtctaaca
     5881 gttttgctct cgtttttcaa ctaaaaagac tagaaaaagt gaaatacttt ttctagtctt
     5941 ttgactgatt agttatcata acgttttctt tttgatgaac tcgggattcc taataaatca
     6001 cgatattttg ctactgttcg tcttgagatc gctatctcat cttttttcag caattcaacc
     6061 aatttctggt cagacaacgg cttgtttttg tcttcttgat cgactaattc ctgcagcttt
     6121 ttcttcgctg tatctgctga aaggtcttct gtctgttctg tactattcgt aggaattcgt
     6181 gtagtgaaaa atttttttaa ttcaaataca ccgaagtctg tttccaaata tttcccgttg
     6241 actgcacgac tgaccgtgga ttcatgcaca tctatctcag ttgcaacttc ctttaacgta
     6301 agaggcttga ttggacgttc cttgtcgata aagaaagctt tttgccggga aacaatgact
     6361 tgagcaaccc gcaaaattgt atccccacgt tgtaggatcg ttttcttcaa ccattcgaat
     6421 tcctgtttcc gttcttttaa ataattttca gtttctttat ctgcttgttg tgacatttgt
     6481 ttgaagtaac tctcttgaaa gcgtatattt ggctgatttt ttcggtttga gataacttgt
     6541 acatttttat cgtcgtccac taatacccgg acatcaggaa taatgtacaa ttcgctgcta
     6601 cggtcgaaaa tccggccagg gcttggactc aacgtttgta aatagtcgaa tatctgctga
     6661 acagcatgta gatcaacaga aaaacgttgt gcgatttctt tccattttcg ctccaccagt
     6721 tcctcaaaac attcttccaa cacgatataa gctaattccg gcgcataatc atctcgttct
     6781 gtttgaagca tgagacattc ttgcaaacta cgtgcaccta ctccagctgg ttctaattgc
     6841 tgaatcagag tcaacgcatc gagcatttgg ataggcgtag ctccaatctc ttttccggct
     6901 tcttctaaac taatcgtcaa aaatccgttc aaatcgatgt attctacaag ataaagaacg
     6961 attttcctca aaaaagtatc tcggtaattc aaatggactt gttcgatcaa tgaatcaaat
     7021 aaagaccctt ttgtatcagg aatctgattt aggtaatttg tctcttctcc ttcataagaa
     7081 gatgaagaag cttttatgta atctggctgc cattccggct caacaacttc caccaatgga
     7141 ttttccattg cttgattctc aacgaatgcc aacagctcct cactgttata ttgtaaaact
     7201 tggatggact gttgcaactg ttgcgtcatg gctagtttct gtgtctgctg ctgtttttgt
     7261 gaaaaatttt gctcaaattt catttttttg tccaatcccc ttgtaatttt ttatctgttt
     7321 agttacaatt atcccagtgc ttgcgtcctt agtgtagtgg atatcacgta agattccggt
     7381 tcttgagacg ggggttcgat tccctcagga cgcgttctac tgctatttta gcataattta
     7441 cgaatagttg cttctttatt tttaagtgaa aactgtccgc caaa
//
LOCUS       DAZKNV010000094         7126 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000094 DAZKNV010000000
VERSION     DAZKNV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.096"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..525
                     /locus_tag="ACG8M1_002591"
     CDS             <1..525
                     /locus_tag="ACG8M1_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFQ0423248.1"
                     /translation="SEKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTI
                     SNEINQYREREPEIQPAEVKQEHKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRT
                     LHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKN
                     EIYYEQQLSQKERV"
     gene            586..2046
                     /locus_tag="ACG8M1_002592"
     CDS             586..2046
                     /locus_tag="ACG8M1_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFQ0423249.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2057..4261
                     /gene="topB"
                     /locus_tag="ACG8M1_002593"
     CDS             2057..4261
                     /gene="topB"
                     /locus_tag="ACG8M1_002593"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0423250.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            4277..4426
                     /locus_tag="ACG8M1_002594"
     CDS             4277..4426
                     /locus_tag="ACG8M1_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423251.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4500..5093
                     /locus_tag="ACG8M1_002595"
     CDS             4500..5093
                     /locus_tag="ACG8M1_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFQ0423252.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            5109..6008
                     /locus_tag="ACG8M1_002596"
     CDS             5109..6008
                     /locus_tag="ACG8M1_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFQ0423253.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            6011..6496
                     /gene="ssb"
                     /locus_tag="ACG8M1_002597"
     CDS             6011..6496
                     /gene="ssb"
                     /locus_tag="ACG8M1_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0423254.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            6862..7122
                     /locus_tag="ACG8M1_002598"
     CDS             6862..7122
                     /locus_tag="ACG8M1_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423255.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
BASE COUNT         2624 a         1215 c         1483 g         1804 t
ORIGIN      
        1 tcggagaaag ctattcctta tattgcagca tggacgaaga atggtcagac gttggatgat
       61 aaggaagcgg cggaacgtgg gaaaatcatg aatgatgtca gccgtgtcgc aaatgaattc
      121 attcaaacca tttctaatga aatcaatcaa tacagagaaa gagaaccaga gatccaacca
      181 gcagaagtga agcaggagca taaaaatact gtagaaacgg cagagaataa gaatattgtg
      241 cccgttggtt cactttggat cgacaagaaa gacgggaaag taatggaaga agatacgggt
      301 cgaacgttac atttgaagga tgcggcgttt attgaagatc cgcagcataa tcaagtgatt
      361 ttaaaaggaa aaagttatgg aaaagagatt caaacggcgt taccttcaga agaatttgcg
      421 ctaggaaatc cattccgatt ttcacttgaa acagtgtcag aagtggccaa acgaaaaaat
      481 gaaatctatt atgaacaaca attgtcacaa aaagaacgcg tataaaacaa gtaaaaaaga
      541 ctatctgaaa aacggatagt cttttttctt ttgggaggtt tgaaaatgac cgaaaaaaaa
      601 atgagtctta ttgatcgatg taaacagatc gatatagtgg attttgctcg aaacaatgga
      661 atggctgtag tcaataaagg acgagactat cgcttagaag accatgattc atttgttttt
      721 gatcgaagaa aacaacgttt ttattggaac agtcaaaata ttagtggcga cattattgaa
      781 ttagctaaac tttttttcat agacaaagag atccaagact ctaagcaaca atttaaagca
      841 gccactgatt ttattctaaa gaatgaagac aaaacagaac gagtggaaaa tcttcatttt
      901 gaaacagaaa agtacaaaga tcaccccgtt gattatcaac cactcacaga aaaaggaagg
      961 aattatctga aggaagaacg aaaactacca gagtggctga ttgattatgc agaaaaagaa
     1021 gggttgattg ccgaactaaa gccaaaatat gaacggcaaa atttcttagt tcgagacgat
     1081 cgtttagatc atgcggtcgc ctttttatgg aaagatccac agacaaaaga gacagtaggg
     1141 gcgagttatc aaggaacgtt cattgattat gaacgttttg gtgagagagg cacatataag
     1201 catatagata aaaattcgac agcgaatcat ggctttaacc taaagatcgg tgaccctaag
     1261 cagttaaaat tttttgagag tagtattgat ttacttagct atgctgcact gaatcgtgat
     1321 cagttaaacg atacgtggtt agtctctatg gaagggttaa aacaccatgt gatcagtcat
     1381 tattttggtg aggcagtatc tgaattgaga aagaaacaag cctttcctca atccatcgag
     1441 atttgtgtgg ataatgaccg tgcaggacat attttctacg aaaaagaaca attaatgggc
     1501 gcagtcgatc catttacgaa tcagaaagta cgttgtgaac gaggaatcgc taatgattgg
     1561 caagtgccaa aagaatacaa aatcatttat gaagaagtcg caaaagaaga aaaggtcaca
     1621 ccagaagcta ttatggccat acacaagaca gaaaacaatc tgcaattaac gaaccaactg
     1681 gtttccgctc acaaagtaaa tgcgtttttt ggccagcagc tttctgttaa cgattcaata
     1741 gaagccatta atttgaaaga tatttgtaga gaagtcgcaa aagaattaaa agtttgtgaa
     1801 cgcgtggatg gtacgtacga ttttgatcgt ttttatcaag aaaaagggga tattaatgcg
     1861 cagattcttt tctcttataa agcagaacaa tactacaaag gctataaaaa tcatgaacat
     1921 gaatttatac ctgaagtaaa aaaggactgg aacgatcaat tgaagcatga gatccagcaa
     1981 caagaaatca gaaagcaaaa acgtgccatg ttgtttcaac aaggcagaca acaagaaagg
     2041 gagtgaaatc gtcatgatga aaaccgttat tttagcagaa aagccgtcac aagcgaaagc
     2101 ttatgccgat agcttctcta aagccactcg aaaagacggg tattttgaaa tccaagatcg
     2161 attgtttcct ggtgaaactg tgatcacgta tggttttggt catttagtcg aattagattc
     2221 gcccgatatg tacgatgaaa attggaaaca atggtcatta gaacatttgc ctattttccc
     2281 tacacattat cactatcatg ttcctaaaga taagaaaaag caattcaagg tggtgaaaca
     2341 gcaacttcaa tcggccgaca ccattattat tgcgacagat agcgatcgtg aaggggaact
     2401 gatcgcttgg acgatcattc aacaagtagg cgccgatcaa ggaaaaacct ttaaaagact
     2461 ttggatcaac tccttagaaa aagaagccat ttatcaggga ttccagcagt tacgagacgc
     2521 aaaagagacc tatccaaaat ttgaagaagc acaagcacgt cagatcgccg attggttaat
     2581 tgggatgaac ggtagcccac tgtatagttt actcttgcag caaaaaggca taccaggaag
     2641 cttttcctta ggcagagtcc aaaccccaac gctttacatg atttatcaat tgcaggaaaa
     2701 gattagaaat ttcaagaaag aaccttattt tgaaggaaaa tccgaagtaa tcgctcaaaa
     2761 tggcgcattt gatgcgaagc ttgatccgaa tgaaacccaa gcgacgcaag aagcatttga
     2821 agattattta aaagaaaagg gggttcaatt gggaaaacag ccaggcatga ttcgccaagt
     2881 tgaaaccgag aaaaaaagcg cggcaagtcc acgtcttttt tctctatcca gccttcagtc
     2941 taaaatgaat cagctcatga aagctagtgc caaagacact ttggaagcca tgcaaggctt
     3001 gtatgaaggg aaatatctaa gctatccacg aacagacacc ccttatatta cggaagggga
     3061 gtatgcgtat ttgttggatc atttagatga atacaagcat tttttaaagg ccgaatcaat
     3121 cccaacccct attcatacgc cgaatagtcg gtatgtgaat aacaagaaag tccaggaaca
     3181 ttacgcgatc attcctacaa aaacggttat gacagcagcg gcttttgaac aactaagtcc
     3241 actgcagcag gccatttatg aacaagtgtt aaaaacaacg gtggccatgt ttgcggaaaa
     3301 atatacctat gaagaaacaa cgatcttgac gcaagtccag cagcttcagt taaaggcaat
     3361 cggaaaagta ccgatagatc taggttggaa gaagttattt ggcaaagaga acgacggaaa
     3421 agagaaggaa gaagagccgc tacttcctaa agtgacaaaa ggagaaatgg tgacggtaga
     3481 tctacaagtc cttgaaaaag aaaccaagcc accacagcct tataccgaag gtacgttgat
     3541 cacggcgatg aaaacagctg ggaaaaccgt tgatagtgaa gaagcgcaat ccatattgaa
     3601 agaagtggaa ggaatcggta cagaagcgac acgggcgaat attattgaaa ccttgaaaca
     3661 aaaggaatat atcaaggtag agaaaaataa gctcgtggtg acgaataaag ggattttgct
     3721 ttgccaagcc gtggaaaaag agccgctgct tacgagtgcc gaaatgaccg ccaaatggga
     3781 aagctacttg ttaaagatcg gtgaacgaaa aggaacacaa accacttttc tagccaatat
     3841 ccaaaaattt gtctctcact tattggaagt cgtaccaggg caaatccaat ccactgattt
     3901 tggatcgacg ttacaagaag tgaaagcagc cagtgaaaag caagaagccg cgcgtcattt
     3961 aggaatttgt ccaaaatgcc aggaacaaga agtcttactc tatcaaaagg tggcagcatg
     4021 tacgtctgaa gcctgtgatt tcaaactatg gacaacgatt gccaaaaaga aacttacagc
     4081 gacacagctg aaagagatca ttcaaaatag ccgaacaagc caaccagtga aagggttaaa
     4141 aggtcagaag ggttcgtttg aagcaacgat tgttttaaaa gaagacttca ctacaggctt
     4201 tgaattttct gaaaagaaaa aaacgaactt caagaaaaga acacgacgca ctacaaaata
     4261 atggagggtt aatcttatgc gtaatacaac acacaaacaa caagaaatcg aaaatcaaaa
     4321 agccaaaatt cgttcagaac aggaaaaaat gcgtgccagc aaacgaagac tgcagcaatt
     4381 gaagaaccag cagcggattc aaaaagaaat cgaattagat cgataaattc ctttcttgtt
     4441 aatataaaac taacatgtta tagttgtgtt agttttatat taactttagg ggaagagtaa
     4501 tgaaagacaa aatccaatgt atttttgata aacataatgg caacctatcc ttgaaggatg
     4561 ctagaagtga aggattatcg cctatgacgt tagatcgatt agccgaaaag gataaaatag
     4621 aaaaggtagc accaggtttc tataccttaa aggatgcgtt cgtggatgaa ttgtatctcg
     4681 ctcagagtat ctattccaga gggatttttt ctcatgagac tgcgctcgat ctttttcaag
     4741 taggaacata tatccctaaa aagatcaata tgatgtttcc taaaggatac aatgtatcaa
     4801 aggagaaatt agatcagtat gccattcaac cgcattacac taataaagaa aattttgacc
     4861 tgggagtcac agaaacagaa agcttttacg gcaataaaat tttagtctat gatttagagc
     4921 gaacgttatg tgacatgtgg aatccaagat acaaagcaag cgtagaggta aaacaagaag
     4981 cattaaaaga atatatgaca agtaccagta gaaatacaaa taagctaaga agatacatgg
     5041 atattttaaa atcaccaaaa gaaatgactt tgtatatgtt gccactttat tgagaggagt
     5101 aaagatgaat gacaccgaca caatttaaag agaaaacaag aaatttcgca gcagagaaac
     5161 atttaaaccc acaaattgtc caaagatatt atatgatgga aaaattatta gaatgtattg
     5221 ttgaatcgcc ttatcatgat gattttgtat taaaaggggg atttctgatt ggatcaaaat
     5281 acgggttaga aaaccgttca accgttgata ttgatacgac ttatcgaaat tcgaaactaa
     5341 caaaagaaaa gttagaaact gttttttctg aattaacagc taatcctaca aaagatggaa
     5401 ttcgttttga attaaaggga ttaacagaga cgagggaagc cgattattat ccaggttttc
     5461 aagcaaagtt tattgcttat cttgaaaatg cacgtgtacc ttttaaatta gatattactt
     5521 caggtgattc tattattcca gcagcattga tgtatgaaca caaattaatg tttgaagata
     5581 aaacgattca tattccagct tatcctacgg aacaaattct agctgaaaaa ttacatgcca
     5641 cgtttagttt tggaaaagat aattcgcgca tgaaagattt ttatgacctg tatatgattc
     5701 cgaaattaga acgtatcgat gagaaaaatt tgtataagag tgttcaagga acattcaagg
     5761 aaagaaataa tcaatcggtg tttaagcatt tgtatgatca ggaaatgcct caattggtga
     5821 aagatgaggg cttgagagaa aagtggaaaa gataccaaca agaaaactat tttgccaaag
     5881 acatttcttt cgaatctaca ctaacttccg ttgattccct gatgcaatca attgtagagc
     5941 aagagaaggc agaacgaaaa caaaatttta agagatcaca acaaatgaat caagaaatgg
     6001 agagataaag atgatcaata atgtaacttt agtagggcga ttaactaaag atccagattt
     6061 acgttatacc gcaagtggca cagcagtggc gactttttcc ctagccgtta atcgtaattt
     6121 cacgaatcaa aacggcaatc gagaagctga ttttatcaat tgcgtgattt ggcgcaaacc
     6181 agcagaaacg atggcgacat tagctaaaaa aggcagcttg atcggcgttg tcggacgaat
     6241 tcaaacacgg acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc
     6301 cgataacttc caactattag aaagtaaagc agcgacagaa agccgtatgc acgctgatca
     6361 atcgtccagc agtccaagcc ctaccacctt tgaacaacgg gatacagcga cgcctaacaa
     6421 caatggattg aacgcttcac agaatccatt tggtggacaa tcaatcgata ttagcgatga
     6481 tgatctaccg ttctaagtag cattttctat tggttgcatt tgctacggtt tatgttataa
     6541 tttagacaac aaaaagaatt ttcaatctat aaccaaaaac cactagctgg cgggctagtg
     6601 gctttctttt acgtttctat tataagaatt aacgggtagg cttactgtct ttcttggcaa
     6661 atttacaatc aagccatttg cagatatagt gcgcggctac ttctgccatg attgcaaaaa
     6721 caaaatcaaa aagaattttc aaacctataa cctcctcccc ttgccagatt aggccggggt
     6781 agcagacagc aagactatta tagcataatt gaaatatcca aatgattgga tttttgctat
     6841 aattttagcg aggtgattgt gatgaacaaa tatgttggtt tgcttgataa aatccgagta
     6901 ataaaaacgc aaccgttatt ggttcgcttt actttacaaa cgattcatga atcgattaat
     6961 tgtgtagttg cagatattga aattatcgat aaattgctaa ttatggatga tggaaaatac
     7021 aatattgccg tcacaggtca cttcaataaa cgaaatcagc tagttattgc tagcatgtat
     7081 gttagaaatc ccgatcattt tacgcgatcg atgggcatat aaataa
//
LOCUS       DAZKNV010000095         7067 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000095 DAZKNV010000000
VERSION     DAZKNV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.097"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(216..506)
                     /locus_tag="ACG8M1_002599"
     CDS             complement(216..506)
                     /locus_tag="ACG8M1_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFQ0423256.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(642..821)
                     /locus_tag="ACG8M1_002600"
     CDS             complement(642..821)
                     /locus_tag="ACG8M1_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423257.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(818..1168)
                     /locus_tag="ACG8M1_002601"
     CDS             complement(818..1168)
                     /locus_tag="ACG8M1_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423258.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(1161..2486)
                     /locus_tag="ACG8M1_002602"
     CDS             complement(1161..2486)
                     /locus_tag="ACG8M1_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFQ0423259.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            2936..3550
                     /locus_tag="ACG8M1_002603"
     CDS             2936..3550
                     /locus_tag="ACG8M1_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0423260.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(3715..4719)
                     /locus_tag="ACG8M1_002604"
     CDS             complement(3715..4719)
                     /locus_tag="ACG8M1_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423261.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(5178..5435)
                     /locus_tag="ACG8M1_002605"
     CDS             complement(5178..5435)
                     /locus_tag="ACG8M1_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFQ0423262.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(5428..5697)
                     /locus_tag="ACG8M1_002606"
     CDS             complement(5428..5697)
                     /locus_tag="ACG8M1_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0423263.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(5828..6007)
                     /locus_tag="ACG8M1_002607"
     CDS             complement(5828..6007)
                     /locus_tag="ACG8M1_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423264.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            6105..6341
                     /locus_tag="ACG8M1_002608"
     CDS             6105..6341
                     /locus_tag="ACG8M1_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423265.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISF
                     FLLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
     gene            complement(6388..>7067)
                     /locus_tag="ACG8M1_002609"
     CDS             complement(6388..>7067)
                     /locus_tag="ACG8M1_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423266.1"
                     /translation="EDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFIQRVEEQLYLE
                     SETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENFVSYT
                     ICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLTCGTESIVLMG
                     MDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPYQR
                     FERKKRQ"
BASE COUNT         2173 a         1334 c         1022 g         2538 t
ORIGIN      
        1 ttcgaaatta aaataatcac tttttattac tttaaaattt tttattaatg ataagaaata
       61 tgttttgcga gcagcaacta gaataattta aacattacta aactgtctat attgttacta
      121 ataattccct tcttatagtg cattttctta gaaaaaaaca atattacgat atcatgatat
      181 taagatatcg taatattata caattgtgat tgatattata tatgtttttt tattttttta
      241 tcatgtttaa tcttgaagga atcatattct ttttctaaag acaggagctt ttcataaaca
      301 tcagacatgt ttaaactaga ggccaggctt aaatcataaa cgaatgaagc aggtaatgat
      361 tttattctac gttgtcgggt tatccagctt gcaaccgttc cttgtgggta ggcatataac
      421 tcacaaaatt gttctacagt gattcctaaa ttcttgataa tgtaaacatt gatcgggtgc
      481 gagtaaacaa atgtattgat agacatggtg cgtaagccta ctttctttta ttattgcgtt
      541 tgcaataata gtttaacaca cgcattattc tagtatctac tcctatttgt aaaaacaaaa
      601 aaggattcat agagataact ctatagaatc cgtaaaatac cttatatata taacgggaag
      661 atataaaacc taaaattatg ataacctgct gcagcttcta catagaaaga gaagcgctca
      721 acaccaacct catttatcaa acgttggcca taaccccaaa tctcttctga tagctgatca
      781 aaggttatat actttagctc atattgctgg ataatgttca ttctaatcga ctccatttat
      841 tatcctggta aaattcgata tgacgtattt cgtcgtagtg aattttgtct tttccaacgt
      901 agatccccag ctcatcacta cctaagatct tgccaatgat atcttctgga tagtatcctt
      961 cagcgtttcg ttcttctttt tgaatagata ctgatctatt ttttatgact gcagcgttca
     1021 atacttccgc aatctcttca gtcgtcattt gttcttttgc taaattttga ctggttcgtt
     1081 gttcattgtc ggcatcaatt tcttcagtat gatcagataa ataaaaccct gcccacttta
     1141 aacgtccacg atcattgtaa tcaatcattt ttaattcccc catttccgcc cgcatgacca
     1201 ccaacaagtg tgcttctagt aatgcttcta gcgccttcta acattgaaga agcatgtaca
     1261 atcgacgtaa aaccatattt ttgccgaatc ttgtcaataa ttttatctaa attttcttcg
     1321 tcaatttgct tttgtggatc actaaataaa tccagctgaa gcgaatcggt gtacacaagc
     1381 ttgctatagg ttattccaac atgccttact tcttgtcctt cataatactt atcaaacaag
     1441 aaaagacaat aattctgcaa ttcctttgta ttatctgtga tagggatctt catctggtgt
     1501 gaaaaccctg gtctcgtttc taagatcgac gtgccaatgt gtaaatggac acaacctgtt
     1561 ttacagttat gctgcctaat gcgtatcgct acttgttccg ccatttcttt taccaccagc
     1621 tcgatttcat ttcttctagt ataatctcgt ggtaacactt gtgaatttcc atatgatttt
     1681 tcctttgtcg gttctggtgg gattgctata tctgttcgat cgatcccatt agcatggaag
     1741 tacagctgta agccaatcac acctagtcta ttcttaatcg tataaggatt ccagttagca
     1801 agatctctaa tgctcataat ccccatctga ttgagtcttt ttttcattcg agagccaatt
     1861 ccccaaaagt ccgtcatttc aggaatattc catacttttt caggaacgtt ttcgtacgtc
     1921 cattccgcaa caaatccttc attatgcttt gcttcgttgt ctaaggctag tttagccaaa
     1981 aggggattat ctccgacacc tactgtagca atcaatccta gctcttcttt aatattctcc
     2041 tggatcattt gagccagctt ctttctccgt tgacttcgtg ttccttcagt cgtaaaaaga
     2101 ttcagtgatc gggtcacttt taagattgat tcatcgatcg agtaaatcag tagatcttca
     2161 tcagccacat atcttctgaa aatattattt acctgcatat ttcgcttgat atataggttc
     2221 atacgtggtg gaacaacgtg tagtgtttta ggaaatggtt gtggtaagtc acgtggtcta
     2281 ctcacatttg taataccata ccgctttttt gcttcaggag aagaagctaa tatcaatcct
     2341 gaaccagtat tatcagctcg actcataaca acaagttctg ttgttaatgg atctaaattt
     2401 ctttctatac attcgacact tgcgtaaaag cttttcatat cgattaaaaa gtaatcattt
     2461 actggctctt ttgaataatc catcataaat aacactccat tctttcacat tatacaaaca
     2521 tatgttcgat attgtaaaga agaaatagct aaatacataa aaaaagaagc ataggtatgc
     2581 tatcaccctg cttcttcttt tgatttgtat gatcaattta ttctatcact ttactaatta
     2641 atttgaaaat ctaataaaaa ctctcactct aaaagagtga gagactgcaa attagagtac
     2701 ggactttttt ggagttccgt tctttaatat taacaaatga ataaaatcct tacaacattt
     2761 gagaataagt tatcagtaga cacttacaaa aaattctcat actatttcct ccatcattag
     2821 tttttgtcta tataaggttt accctaaata gacactggta taacattgaa aaatatggct
     2881 tcctcgtgta tgattagggt gtattttaaa tagttgcaga aagtaggtaa aagttttgag
     2941 agttgcatac atacgtgtct catcgatcga tcaaaatgaa caacgccaga ttgaagaaat
     3001 gaaaaaattc ggtgcagaga gaattttcat cgagaaacaa tctggcgcaa cgattactca
     3061 tcgacctgtt ttccaagaag cattagatta cgtccgagat caagatattt ttattgtgga
     3121 agctattgat cgacttggaa gaaattatga cgagatcatc gcttcagtca attacttgaa
     3181 gaagaaaaat gtgaagctga tcattactag tttaccgatc atggctgaag caattggcaa
     3241 tcctctcctg gataaattca ttaaggatct gatcatccaa attttggcca tgatcgctga
     3301 acaagaacgg actgaatcga aacgtcgcca ggcacaagga attaagatcg caaaagcaaa
     3361 cggcgtctac aaagggcggc ccaaattata cagtgcagac gcaaaagatc cccaacgtcg
     3421 ccttgtttac aaaagcatcg ttgaagatct taaaaatggt gttgcgattg ctaagattgc
     3481 taaagactac aatgttacga gacaaaccgt gtatagaata aaaaaagaca gcatggtcaa
     3541 tgacaaatag ttgatcatgc tgcttttatt atcttctcat ctttaatttc ctacatataa
     3601 ttactatcta taaaattaag tcttactcag aacagataaa gcataaaatt ccaacaaacc
     3661 attttttact taactaaata aagagtctgt taatataatc ttcacttatt tacgttaatc
     3721 ccctactgta tttgttggtt ccttatctat attttctaca aaatccttat tatcttgtga
     3781 tttagcttcg tataattctt tgtatgtcga cacattggtt atactaattc ctatagctag
     3841 ttcttgagac tctacttttc tctctagctc ctttgacaaa gtgatttgag atttatttgg
     3901 ttccgttgga gtcaattcta tagattcttc ataaaaatct ctatacataa agctatcatt
     3961 aattttataa aaaaaattaa atgtttttag cactgccata taacattcaa aacattcttc
     4021 tatagttggt ttacttcctt gaggagaatg aaccaattta ttacgttttt ctatgaaatt
     4081 tttaatttcc tttcttattt ctttcggaaa ctcaatatta aagtaccctt taaacatgct
     4141 ccctaataat ttgtctacag ggggagattg taaattctca aatattagag ttaaatcagg
     4201 tttctcttgt tgataaaatt cctttacccc tatttcacag gctgtaatta tcgaaataaa
     4261 cctatctcta gtatttgata tatttttact tcttttaagg agtataagag aaaaggggat
     4321 actttcgtgt ccatgcatgt aattaactaa ttgttgagct tcagaagtta tatctctaat
     4381 tatatagtta acggaattag gaagtgtctt taactctaat gaaatttcta tccaattact
     4441 atcttctaat ctgtatatgc tcgaagtata atttgattcg tcagcaagca tcgctacatc
     4501 ccaaacactg atcataaaat cttttaaacg ttcaatcatt tcagcaatat tgctaaaatc
     4561 agctaatttt tctttagaat aaaaaaaaac atttatatca gaatcaataa attctatttt
     4621 ttttattact atatcgtcat cattatcttg accatttatg tttattgttc cctgagtggg
     4681 gagtacttct ttcaaattca agttaaattt atattccatt acttctcctc caatatataa
     4741 aaattactta actgtatcca aatttaatat gtaaataaat cattaatttt tagctaaatt
     4801 ctatgagaag tttatttttg ttgtttttgc taattaacta aaactagtac aaaaaattta
     4861 aaatagatta ttaaacctat tgcttattct attcagtcat atatataagc gtcatccttt
     4921 agtaactaac atcccacact acaatagtat tataacatat ctattcaact tcaaattgtt
     4981 gaaatttaag ccatttatat ttacttttcc tcaactttag aaatgatttt actaacctta
     5041 tatccgtaat acgcgtaaca aacacattca ttaataacaa tcaacactaa gctatattag
     5101 ctttttaaat gactagggta aataaaataa ggatcaaaaa cttttaagtt tctgaccctt
     5161 tccttacttc cgattggtta atagtgatct tttgcagaat aaataaatat cgtttcattt
     5221 tcaactctat atatcagtct atgttcatct gtaattcttc tggaccattt tccagataaa
     5281 tcatgcttta atggctcagg ttttcctaat ccagcaaagg gggaacgatc gatatctttt
     5341 attaacttgt taatcttttt tatattgctt ttgtttcctt gctcatgcca ataaagataa
     5401 tcatcccaag catcatcaga ccaagcctta atcatcagat tcaacctcga ttaagtcatg
     5461 tgttttaaat gcacctttgg agaattgttc atctcctcga cgaatttttt ccatgacgta
     5521 attattagaa agtgttctca acgtttcttg catagaatca taatctcttt ttgataatac
     5581 aacaactgta tcttctacat ctttacttgt tacaataagt gtttcagcat cctcattaac
     5641 ttgtttcata taactacgta aattttggcg gaaatttgaa taagctactg cttccattcc
     5701 tttcacccct tatttatttc tataaaacaa ttgtacatta tattgtacaa ttaagcaaat
     5761 gattaatatt ctaacttctt ataattaaaa gtgctatcac ttttagtttt taggataaaa
     5821 agtgacgtca ctttttgagt gctggtacct caaatcctgc tttttcttgg gcaatcaata
     5881 aatctaacgc aatacacata atcctggatt cacttttgcc gtacttctgc tttagttgct
     5941 gcaattcttt ttgtctcttt tcatccaacg taacgggtaa ccgtttattt cctattgcaa
     6001 ttggcattag tactctctcc tttcatcgaa ataaccctat gaaaaatatg gctgcaatca
     6061 tcttgaatag tagactcaca agggctaata caaagcgcca aaagatcaaa caaaatacca
     6121 gtattgccaa aaatactacg aagtttaaat gcacagctgc agcatggcgc ataagtattt
     6181 cgccaacaaa taggactaac aatagaggaa tgattttatt catatggatc tccttctttc
     6241 tcttaggtta tcgggtgttg cccgcttatt tcgcaccacc taagcggcgg gggcggttgg
     6301 agcgattggt gcgaaataag aaccattccc ttagttacta ggttttttgt ccttatttca
     6361 cacattctca cttttcggta taaatgatta ttgccttttt ttcctttcaa atcgttgata
     6421 tggcattcgt ttacggtcaa gttcattttg gatttcttct gtatcgtcgt aagtataggt
     6481 gtctaaaaaa tcagttaaag tcgtgtacca gtcgtcgcct gggttatcta cttcttctac
     6541 atattccctc aaaaatgctt cgggtacagc gagttcataa tccattccca ttaacacgat
     6601 agattccgtt ccacacgtca aaaatctagt aaatacaagg taataatcgt ctatcgtcgc
     6661 atctttgctg tttagctctt ccatttcttc ttccattaat tccatgctct caaaaattga
     6721 ataatattct gattctgagt aatagtgttt cctgcaaatc gtgtagctga caaagttttc
     6781 gaccagctca ctcctttcta ggtaaacatt catgatgtat ttttctgttt ctagtcgtag
     6841 aagctccgtt ccttttttta ccgtttcagg acgacgttta tacacgtcta aacgattatg
     6901 gctgactgtg accttcgttt gactcgtttc actttccaaa tacaattgtt cttcgactct
     6961 ttgaataaag tacttcattt cttccataca actaaagtct ttttgaatcc gtctgattac
     7021 ttcattcaaa tgttctttgt ttgttaaaaa gtgtgacaca tcttccg
//
LOCUS       DAZKNV010000096         6915 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000096 DAZKNV010000000
VERSION     DAZKNV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.098"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            53..505
                     /locus_tag="ACG8M1_002610"
     CDS             53..505
                     /locus_tag="ACG8M1_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423267.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            519..1208
                     /locus_tag="ACG8M1_002611"
     CDS             519..1208
                     /locus_tag="ACG8M1_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423268.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1333..3684
                     /locus_tag="ACG8M1_002612"
     CDS             1333..3684
                     /locus_tag="ACG8M1_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFQ0423269.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3764..4159
                     /locus_tag="ACG8M1_002613"
     CDS             3764..4159
                     /locus_tag="ACG8M1_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423270.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4484..5101
                     /locus_tag="ACG8M1_002614"
     CDS             4484..5101
                     /locus_tag="ACG8M1_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0423271.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5142..5441
                     /locus_tag="ACG8M1_002615"
     CDS             5142..5441
                     /locus_tag="ACG8M1_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFQ0423272.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5475..5642
                     /locus_tag="ACG8M1_002616"
     CDS             5475..5642
                     /locus_tag="ACG8M1_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0423273.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKKYFYCP
                     KCHRRYGVHGT"
     gene            complement(5687..6157)
                     /locus_tag="ACG8M1_002617"
     CDS             complement(5687..6157)
                     /locus_tag="ACG8M1_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0423274.1"
                     /translation="MEFREGAFDFQTSQQNPSLDRLGRDYEDIKNTVAFMKQKKVALK
                     ILDAQFLDFNTGNELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKG
                     RPIEYSINSTDPQKRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(6163..6843)
                     /locus_tag="ACG8M1_002618"
     CDS             complement(6163..6843)
                     /locus_tag="ACG8M1_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HFQ0423275.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
BASE COUNT         2333 a         1002 c         1368 g         2212 t
ORIGIN      
        1 atcttatcgt agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa
       61 aacgatacta agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa
      121 tttagattct gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa
      181 taaaaaaatg agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga
      241 atttggtgat ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga
      301 taaaattgtt gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt
      361 tagttataaa caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc
      421 gattaaggat ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga
      481 aactaattca gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt
      541 ctgttgggct acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag
      601 ttatttcaga tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata
      661 aagtacttgc attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg
      721 ataatccaga tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag
      781 tgacagaagc aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa
      841 ttatgcctcg aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag
      901 caggaggagg aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta
      961 tgggtgtaaa accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg
     1021 atggaagagt aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa
     1081 tggcattgta tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa
     1141 tgaatatagg tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa
     1201 atatttaata aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg
     1261 acaaacacta aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag
     1321 caggggattt ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac
     1381 agtaatgtta cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc
     1441 tatggactta ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt
     1501 ggacctacca ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta
     1561 cctaaaaata ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt
     1621 ggcttcgatg gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat
     1681 gcagggttta atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta
     1741 tttgatatga gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag
     1801 caatggttaa atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat
     1861 caaagaaatt caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc
     1921 agtgaagcaa cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa
     1981 ggtaactcgg gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt
     2041 gaagacggta cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc
     2101 cgaaaattta tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga
     2161 ctattgtcta gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa
     2221 ttaactagat ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat
     2281 cttactggta ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa
     2341 ttgaataata ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca
     2401 gcattagctt attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca
     2461 gcaaaaaatc taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg
     2521 ttaggggaag aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg
     2581 tcatatagcg ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc
     2641 aataacgggt atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat
     2701 ttaggttttc ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga
     2761 agtggcaacg gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt
     2821 aatgagttat caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt
     2881 ataaatcaga tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg
     2941 aaccctcatt tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt
     3001 tcttctcctg taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact
     3061 aatagcgagg gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg
     3121 cctcacttaa ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt
     3181 gtttctgact ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa
     3241 ttaggaatac aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca
     3301 tttagtctag aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa
     3361 agaaattctg attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct
     3421 attgatagat ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca
     3481 gtaacaaata gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt
     3541 tcatttttca ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat
     3601 tttattggag atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa
     3661 gaaaatagaa gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt
     3721 ttaaatatat acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga
     3781 aatagaatgg aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt
     3841 tatgtttgtt atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta
     3901 ctttgcgaat actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc
     3961 accttatgat ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga
     4021 aatgtggttt gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa
     4081 ttatattgta aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata
     4141 tagtgttgta atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct
     4201 gatgtgaaaa ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat
     4261 ttaatggcag accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca
     4321 tgcgggagtg taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt
     4381 tgtttatgta tggcataata accacataat acaatttgaa acgtttctga tttaatctga
     4441 ttgttttgaa acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta
     4501 tatccgggtc agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt
     4561 aggaatccct gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc
     4621 tgaatatcaa ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt
     4681 agatagacta ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga
     4741 aaagcagatt gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca
     4801 actagatggg ttagagacgc ttatctctga cttaattctg caattactca gctatatggc
     4861 cgaagacgag cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca
     4921 aaagggtgta aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta
     4981 ttctgactgg aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa
     5041 acgaaatacc ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg
     5101 atagatataa cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa
     5161 gggtcgtttt tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc
     5221 actctttaaa cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg
     5281 gtcagtattc taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc
     5341 gggacttgat tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt
     5401 taattagtca acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa
     5461 ggaggaaaat ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt
     5521 ttaatcgaaa tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt
     5581 atcaaaaaaa atacttttac tgtcctaaat gccatcgccg atacggggta catggaacat
     5641 agaaacgaaa tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg
     5701 ctttctttat tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa
     5761 ctggaatgcc ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat
     5821 ctgttgagtt aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca
     5881 ataatactcc ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac
     5941 ttagcagtga taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa
     6001 aatctaaaaa ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa
     6061 ctgtattttt tatatcttca taatctcttc ctaaacgatc tagtgatggg ttctgttgcg
     6121 aagtttgaaa atcaaacgcg ccctctctga actccaaata tcttaggctg ttattcccat
     6181 taataccttg atttcagtag acaccgaaaa gccgaagagc gttccatttc ttcggttctt
     6241 tttatatatt cctcgaatgg tctccatgcc cttaatcgtg gaagaggctg tacggagact
     6301 ttgataaaat ttatttcgtc gtttaatagg tcgatggtct tgttctatta aattgttaag
     6361 atacttcaca gttcggtgct ctgtcttagt atataaaccc acactctgta actttctaaa
     6421 ggcggagcca agagaaggtg ctttatcggt cacaattgct ttcggctcac caaactgttt
     6481 atggagtcgt tttaagaaag cataggctgc ttgcgtatcc cgtttctttc gtaaccagat
     6541 atctaaggtt aagccgtccg catcaattgc acgataaaga taatgccaac gtcccttaat
     6601 tttgatatag gtttcgtcca ttttccatga atagaaggat tgtctatttt tcttcttcca
     6661 aagataatag aggactttgc tgtactcttg cacccaacga taaatcgtag tatgacaaac
     6721 atttattcca cgatcatata acaattcctg aacttcacga tagcttagat tgtaacgcag
     6781 gtagtaacca acagcgacaa taatgacgtc ttttttgaat tgtttgcctt taaaatgatt
     6841 cattactctg tcctctctgt cttttttctc aattttacac taaaatagat tttttggaaa
     6901 actttgcaac agaac
//
LOCUS       DAZKNV010000097         6677 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000097 DAZKNV010000000
VERSION     DAZKNV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.099"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..691
                     /locus_tag="ACG8M1_002619"
     CDS             <1..691
                     /locus_tag="ACG8M1_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFQ0423276.1"
                     /translation="YIENETDSVVLVSSEKVIDICENKILTSAFFEQNGFKTPEILNS
                     SEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSEYIDNPLIQEYILGEEYTIDVCLN
                     FDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKKMLEKLNAIGHITIQCIKNEK
                     GIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKNLRYRENYLDKMIALRYDQAI
                     YLDEKGNVYND"
     gene            684..1379
                     /locus_tag="ACG8M1_002620"
     CDS             684..1379
                     /locus_tag="ACG8M1_002620"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0423277.1"
                     /translation="MIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIFPATFDEI
                     YRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLENADTLLTE
                     LRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPISYLLLLE
                     KFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFYQADKKIR
                     SLWEIKNFLGVIS"
     gene            1376..2494
                     /locus_tag="ACG8M1_002621"
     CDS             1376..2494
                     /locus_tag="ACG8M1_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFQ0423278.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            2484..3104
                     /locus_tag="ACG8M1_002622"
     CDS             2484..3104
                     /locus_tag="ACG8M1_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0423279.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            3300..4400
                     /locus_tag="ACG8M1_002623"
     CDS             3300..4400
                     /locus_tag="ACG8M1_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0423280.1"
                     /translation="MAKYYNKKILIMANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKG
                     KNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYG
                     GLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQ
                     TLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNL
                     YSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHE
                     GMANTNLESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYE
                     QRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            4407..4802
                     /locus_tag="ACG8M1_002624"
     CDS             4407..4802
                     /locus_tag="ACG8M1_002624"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0423281.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            4799..5800
                     /locus_tag="ACG8M1_002625"
     CDS             4799..5800
                     /locus_tag="ACG8M1_002625"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0423282.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKIGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKNKIINLIYPKLIEDEHGE
                     YFSPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDIIQNLSDEYYTRAICKCKYKDNWKGISAKFALKNKWVFLIYIYNKLIKR"
     gene            5806..>6677
                     /locus_tag="ACG8M1_002626"
     CDS             5806..>6677
                     /locus_tag="ACG8M1_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0423283.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVS"
BASE COUNT         2605 a          749 c         1247 g         2076 t
ORIGIN      
        1 atatattgaa aatgaaacag actcagttgt attagtttct tcagaaaaag tcatcgacat
       61 ttgtgagaac aaaattttaa cttctgcttt ttttgaacaa aatggtttta aaactcctga
      121 aattttaaac tcttctgaaa ttacaaaatt tcctgtattt ataaaacctc tgaatggtag
      181 ttcatctgtt aacacattta ttgtaaataa tgaaaaagaa ttgttgtttt ttagtgaata
      241 tatagataat cctcttattc aagagtatat tttaggtgaa gaatatacta tagatgtttg
      301 cttaaacttt gattcgacac cagtaagtat tgttcctaga aaaagaatag caactagagg
      361 tggggaaata ctgaagggtc agattattaa agatagagaa ctaattgaga ctacgaaaaa
      421 gatgttggaa aaattaaatg caatcggaca tattactatt caatgtataa aaaacgaaaa
      481 gggaatattt tatttagaaa taaatgcaag atacggtgga ggagccccca ttagcattaa
      541 atcaggagct aattcccctg aatatattat aaagatgata gattcaaaaa aaaatttgag
      601 atacagagaa aattatttag ataaaatgat agcactgaga tatgatcaag cgatttattt
      661 agatgaaaaa ggaaatgtat ataatgatta aagcggtgat ctttgattta gatgacactc
      721 ttgtgtctga atatgattat gtaaaaagtg gatacaaatg tgtagctaga agattagcag
      781 tgcaaaaaat tttcccggct acttttgacg aaatatatag agtcctttta gatctttttg
      841 ctgaagatag taaaaatgta tttaatcgtc tatatgacta ttttgaaatt ccttatagta
      901 aaaaagaaat taaagaactg gtaaatgtat atcgagaaca caaaccagac ataaattttt
      961 tagaaaatgc agatacttta ttaacggaat taagaagtag aggatacaag ctggggatta
     1021 ttacagatgg gtatgctata acccaacgaa acaaattgga tgctttgaaa gtagactatt
     1081 tggtagatta tatttgtatt actgacgaat taggccgtga attgtggaaa ccacacccta
     1141 tctcatatct tttattgtta gaaaagttta atttaaaggc acaagagtgt atatatattg
     1201 gcgataatga gttgaaagat tttataactg ccaaatcaat aggaatgcaa acaattaaaa
     1261 tagaaagagt aaatggtatt tacagagaaa gcagtttgaa gttcaaaaga ttttaccaag
     1321 ctgataaaaa aatacgttcg ttatgggaga taaaaaattt tttgggagtg atttcatgaa
     1381 aagtaaaaga attctattag cttctccaca tatgagtgaa gaaggatatg aaaaagagta
     1441 tgtaaaagaa gcatttgata caaattgggt tgctccttta ggtgcgaatg tgaatggatt
     1501 tgagaaagaa ttagcagaat acgtgggagc tagtcatgct gccgcattat cttctggaac
     1561 agcagctata catttagctt tgaaagcggc tggggtcggt aaagatgaca tagtgatttg
     1621 tcagtccttg acgttctcag ctactgctaa tccaattctc tatcaaggag ctatacctgt
     1681 atttgttgat agtgattacg aaacttggaa tatgaaacct gaacatttgc gaacagcact
     1741 agaaaaatat cctaacacaa aggctgtatt agtagtacat ttgtacggtt tatcagctaa
     1801 tttagacgaa attactaaaa tatgcaaaga atacgatgtt actctaattg aagatgctgc
     1861 agaatcatta ggaacaacat ataaaggaaa atatactgga acatttggcg actatggaat
     1921 ttattctttt aatggaaata agataatcac aacttcaggt ggcggaatgc ttgtatccaa
     1981 tgacaaagaa aaggtggaaa aagtgagatt ttgggctacg caatctcgtg agaaggcacg
     2041 ccattatcaa cacaatgaaa ttggctataa ttatcgaatg agcaatatcg ttgctggtat
     2101 cggtcgagga caattgaaag tattaaatga aagaattgag aaaaaacgat atattcatag
     2161 tttttataaa aaagaattgt ctaaattgtc aaatatacaa ttcatgccag aaaataattg
     2221 gaatgaaccg aattattggt taagtgtcat aacaataaag ggaataaatg cgaatcatct
     2281 tattgatgag ttagacaaaa ataatataga agcccgccca gtatggaaac ctatgcattt
     2341 acaacctgtt tttaaaaatt atgattatat tggcgatgat gtagcagaaa ctttatttga
     2401 cttaggagta tgtttaccat cagatacaaa gatgacagat gaagatttaa aatatgtagt
     2461 atctacgatt aaaagagtga tcaatgatgc gtaaaaaaac tttctatcag ctttttggga
     2521 aaagaatttt agatatccta ttgtcaggaa ttgctctcat cgttttatcg ccgataatct
     2581 taattgtagg ttttttagta agaattaaac ttggttctcc aattatcttc aaacaagaac
     2641 gaccaggaaa aagtgaaaaa attttttcca tgtataaatt tcgtacaatg actgacgaaa
     2701 gagaccacaa tggagaatat ttacctgatg aaattcgact aactaaattt gggaaaatgc
     2761 ttagagcaac aagtctggat gagctacccg aactttggaa tattttgaaa ggtgatatgt
     2821 cgatcgtagg acctcgtcca ttattagtgg agtatttgcc actatatagt gagaagcaac
     2881 ggaaaagaca caacgtaaga ccaggattaa ctggactggc tcaggtcaat ggaagaaatg
     2941 ctattagttg ggaagaaaag tttgatttag atgtttatta tgttgataaa attagtttct
     3001 ttaatgatct tattattata attcagacat gtaaaaaagt aatcaagaaa gagaatatta
     3061 atacaatcaa taacaatatc ccagaaaaat ttaaagggag ttaaatacag cagcttaatg
     3121 caagttttgt gacttgcatt atatttaggt ataaatcaaa gcgagtatat tagaattata
     3181 taacatatgt taaaaaaacg tatagctaat aaaagtatga ttttaaaaat ttgtgtagag
     3241 ttttaaatat actgtttcaa tacgagaaaa ttataaaaaa gtataaggaa aagagagtta
     3301 tggcaaagta ttataataaa aaaattctta taatggcaaa caacgatgat ggtctttacc
     3361 gttttcgagg aatgctcata aaaaacttag tagatcaagg taatgaagtt attgtatctc
     3421 ttccaaaggg caagaatatt cctaaattaa ttgaacttgg atgtcaaatt attgaaactc
     3481 caatagatag aagaggaatt aatccaaaaa ctgactttaa actatttttt aactattgta
     3541 atattttgaa aaaaataaag ccagatatgg tcattgctta tactatcaaa ccaaatatat
     3601 acggtggatt ggcatgtcgg ttaagaaagg tttcttatgc attaaatata accggattag
     3661 gaacggcatt tcaaaaaaag ggggttttga aaagtctcat tgtatttttg tatagattag
     3721 cagctaaaaa atctaaggtc atatttttcg aaaattttga aaatatgaaa acatttcaga
     3781 ctttacaaat tgctaaacaa agtaaataca agctattaaa cggtgcagga gtagatgtag
     3841 aacactttag ttatttagaa tatcctaaag atgagcaagt tcatttttta tttattggaa
     3901 gaattatgaa agagaaaggt gtagatgaac tttttgaagc aatgaaaaac ttatatagtg
     3961 aagagaaaaa ttgtgtactt gatgtccttg ggtattttga agaagattac ggcataaaaa
     4021 ttgaaaaata cgaaaaagag ggatggttaa aatatcatgg atatcaatct gatattcgtc
     4081 cctttgtaga aagagcacat tgctttgttt tgcctagttg gcacgaagga atggcaaata
     4141 ctaaccttga atcagcagca tcagggagac caattattac aagtgatatc ccagggtgta
     4201 aagaagcagt tattgaatcg aagtctggtt atttatgtga aagaaaaaat agttgtagtc
     4261 tctataattc gatgaataaa tttctaaaat tatcatatga gcagcgcatt aacatgggaa
     4321 aaatggggag aaattatatg attaaaaaat ttaataagaa gaaagttgtc gatgaaacaa
     4381 ttaaatcatt atttagttaa aaagatatgt tttgcaaagt atgtgataga aaagagggat
     4441 tctgtggctt cagaatagat atcaaagaat tggcaaaagt ttctgatatt tttttattta
     4501 ctacattaca agaaggaatg ccaagatcta tgatggaagc tatggcaagt ggattgccat
     4561 gtatagcaag taaaatccga ggtaatgtag accttttagt ggaaggaaaa ggtggatatc
     4621 ttgttccagc taaagatgca gaattagtag cagagtgttt gagagaacta atcaataata
     4681 aatctcttag aaagtatatg ggaaatgaga acctttccag aattaaagaa ttcgaggtta
     4741 gtatcgtaaa aaaaagaatc aaagaaatat atgaagaagt tataggtgag agtgtaaaat
     4801 gaaaaatcca atgttttcaa taatagtacc tatctattgc gttgaaaaat atttgaaaga
     4861 ttgcttagat tcaataagaa atcagacatt taaaaatttt gaagcaatac tagttgatga
     4921 cggtagtcct gacgaatgcc cagaaatatg tgactattat tcccaaatag atggacgttt
     4981 aaaagtaatt cataagaaaa atggtggaat aatagatgca cggaaaatag gagtcactag
     5041 tgctatggga gagtatatag tttttctaga tggtgatgat tggcttgcaa atacttattt
     5101 agaaaaatat gcggaagtaa ttactaagta caatccagat ataatatgta gtgggtattt
     5161 tgcatcacgt tccaacaaaa ttagaaaaag agaattgtct tgctcgtttg gatattatga
     5221 caaaaataaa attataaatt tgatttatcc taaattaatt gaggatgaac atggagaata
     5281 ttttagtcca caattatggg caaaagcttt tagaactact ctgtacaagg agcaacaaca
     5341 agtatctggg caagttagtg ttggtgaaga tcatgcatgt acaaaaccat gtatttacca
     5401 tgcaaattcg atatatatga tggaaaaatg tttatattat tacagaataa acgaaaattc
     5461 tataacaaaa aaaccacaac catattattg ggaaggacca aaggctattg gagagcattt
     5521 tgaaaagcag attgatatga ataagtatga ttttcaagat caagtatata gaaatgttac
     5581 acacaattta tttaatgttg ctgtttcaca atttaataaa caggacaaat atttaaatat
     5641 aaaaaaagat attatacaaa atctaagtga cgaatactat actagagcta tttgtaaatg
     5701 caaatataaa gataattgga aaggaattag tgctaagttt gcattgaaaa acaaatgggt
     5761 atttttaatt tatatttata acaaattgat aaagaggtaa taataatgtc agttaagatt
     5821 agtgtaattg taccttgtta taatgttgaa aaatatattg atgagtgtat aaatagtttg
     5881 ataaatcaaa cattgaaaga tattgagatt attttgttaa acgatggttc aacagataat
     5941 acgttggcga tattaaagaa atatgaaaag cttgattcta gaataaaagt ttacgaacat
     6001 aaaaatatgg ggttagggcc aactagaaat cgagggatta aaatagctaa tggagaattt
     6061 ttggcttttg tggattctga tgattttgtt tccaatacta tgtttgaaag tttatataat
     6121 tgtgcaattg cagagaatgc ggacattgca attggagaag taggcatttt ttctgataga
     6181 gaaatagaaa gagtaaaaat aagaaaaagt ctaacgaact taaaaacaat tgaattagca
     6241 acatataata agaaagaatt ttttaagcaa ttctatttca atcgtttata ttcacataat
     6301 gcttgggata agatatatag acgtagttta gtattagagt ttaatttatc atttggtgat
     6361 aacaaaataa tttttgcaga agataattgg tttcaattac aagtatttat gacaaataca
     6421 agaatctgtt tcgtagataa attgtgttat tattatcgcc aacaaaataa ttctataatg
     6481 cataagccaa aaagtaattt ggtttttaga catggaaata tgattgctga ttatgaaaag
     6541 ttgataaggc aaaatggaaa caacataata gataaaaaag cttgtatgtt ggttgcattt
     6601 gatgtactaa ttatggagat ttttaatcaa aaaaacgttg gtggaacatg tgaagattat
     6661 aagaatgcat tagtttc
//
LOCUS       DAZKNV010000098         6644 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000098 DAZKNV010000000
VERSION     DAZKNV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.101"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..859)
                     /locus_tag="ACG8M1_002627"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="ACG8M1_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG8M1_002628"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG8M1_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFQ0423284.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="ACG8M1_002629"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="ACG8M1_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="ACG8M1_002630"
     CDS             complement(2143..2373)
                     /locus_tag="ACG8M1_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFQ0423285.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="ACG8M1_002631"
     CDS             complement(2603..3421)
                     /locus_tag="ACG8M1_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0423286.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="ACG8M1_002632"
     CDS             3582..4271
                     /locus_tag="ACG8M1_002632"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFQ0423287.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="ACG8M1_002633"
     CDS             4285..5787
                     /locus_tag="ACG8M1_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0423288.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="ACG8M1_002634"
     CDS             5800..6276
                     /locus_tag="ACG8M1_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFQ0423289.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="ACG8M1_002635"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="ACG8M1_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAZKNV010000099         6642 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000099 DAZKNV010000000
VERSION     DAZKNV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.102"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1273..1938)
                     /locus_tag="ACG8M1_002636"
     CDS             complement(1273..1938)
                     /locus_tag="ACG8M1_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423290.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2064..4100
                     /locus_tag="ACG8M1_002637"
     CDS             2064..4100
                     /locus_tag="ACG8M1_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFQ0423291.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="ACG8M1_002638"
     CDS             4104..4742
                     /locus_tag="ACG8M1_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0423292.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="ACG8M1_002639"
     CDS             4770..5198
                     /locus_tag="ACG8M1_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423293.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5655..6566
                     /locus_tag="ACG8M1_002640"
     CDS             5655..6566
                     /locus_tag="ACG8M1_002640"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0423294.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         2287 a         1006 c         1221 g         2128 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg tttttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acagcgttaa aagttatttt tggtagtttt aatatattca
     5281 tttttagttg tataaaaata tatcataata aaaacaacaa aaaaatgtct ggaaaatcga
     5341 acataaaagt gtctgatttg aatatcccag cagcggaaga agaaaaacaa aatcgataac
     5401 atttgttcta agaattagtt acgttaaata cggaacgcaa gatagacttg aaaaacggta
     5461 acaaaagaag tagtatatta aggtgtgatg tgctacttga catttattct gctgagcgaa
     5521 ctttctggat tgtgtagcct tatatctatt caggacgtat cgagcagatt agtaaaggtg
     5581 ttcttgatga ttttcatctt gaacaccttt gtttttagca attcgcaaaa aacgaaaagt
     5641 aggagaattg ataaatgaaa aaaagatttt tagcacttgc catcgtacta ggcactggct
     5701 tattgtcagg ctgtacgaat gccggtgaaa aaacagccgt tagttataaa ggcggtacaa
     5761 tcagcgaaca agaagtaatg gatagcttga aaaaaatgca aggagcagat tccgctgtgc
     5821 aacagttgat cgtttatcaa gtatttgaag ataaatatgg agatgacgta tcaaccaaag
     5881 aaatcgattc tcaatatgat caaacaaaga aacaattggg tgattcattt gattcacaat
     5941 tgaaatctgc aggttacaca gaacaaacat tcaaagacag tatcaaacaa agtctagcct
     6001 ttcaagaagg tctaaagaaa catatcaaat tgaccgatga agatttaaaa acggcttggg
     6061 aatctttcca tccagaagtg gaagctcaaa ttatccaagt agcaagtgaa gatgatgcaa
     6121 aagatgtgaa gaaagctgct gataagggag acgatttctc taaattagcc aaagacaagt
     6181 caactgatac tacgacaaaa gaagatggcg gaaaagtgaa atttgattcc actactacaa
     6241 cggttccggc agaagtcaaa gaagcagcct ttaagttgaa agatggtcaa gtttctgatg
     6301 tgatcacttc taccaatgct tcaacttata ctacggaata ttatgtggtt aaaatggtga
     6361 aaaaccaaaa caaaggcaac gacatggata aatacaaaaa agaattgaaa gaaattgcaa
     6421 cagacacaaa attaagtgac agtaccttcc agaataaagt aattggcgaa gtattgaaag
     6481 acgctaatgt aaaaatcaaa gacaaagact ttgaaaatgt tttgagtaca ttcacttcag
     6541 attctagtac agcaagtagt aaataagcgg tataaataaa aaatatgaac tatttaaatc
     6601 aataaaactg ttcatctaaa tctttttatt agaactaaat ca
//
LOCUS       DAZKNV010000100         6535 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000100 DAZKNV010000000
VERSION     DAZKNV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.103"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            89..943
                     /locus_tag="ACG8M1_002641"
     CDS             89..943
                     /locus_tag="ACG8M1_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFQ0423295.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            944..2281
                     /gene="xseA"
                     /locus_tag="ACG8M1_002642"
     CDS             944..2281
                     /gene="xseA"
                     /locus_tag="ACG8M1_002642"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFQ0423296.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            2286..2510
                     /locus_tag="ACG8M1_002643"
     CDS             2286..2510
                     /locus_tag="ACG8M1_002643"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFQ0423297.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            2512..3402
                     /locus_tag="ACG8M1_002644"
     CDS             2512..3402
                     /locus_tag="ACG8M1_002644"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFQ0423298.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            3411..4229
                     /locus_tag="ACG8M1_002645"
     CDS             3411..4229
                     /locus_tag="ACG8M1_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFQ0423299.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            4336..4785
                     /locus_tag="ACG8M1_002646"
     CDS             4336..4785
                     /locus_tag="ACG8M1_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0423300.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            4803..6485
                     /gene="recN"
                     /locus_tag="ACG8M1_002647"
     CDS             4803..6485
                     /gene="recN"
                     /locus_tag="ACG8M1_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFQ0423301.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
BASE COUNT         2208 a         1102 c         1506 g         1719 t
ORIGIN      
        1 ttttttctat gaatcatcat aaacctgtta taaatcggga aaattctatg gtagaatgaa
       61 aacacaaaaa atatctggga gtggttagat ggcagaattg attaacggaa aagaattagc
      121 tgaaaaaatg caggcagaga ttgctgaaaa aatccaaaaa ttgaaagata atggtatcca
      181 tcccggatta gtcgttttat tggtagggga aaatccagcc agccaaatct atgtaagaaa
      241 taaagaacgt gtagcaaaag aaatcggaat ccattcattg gtagagcgtt atcctgagac
      301 gatttctgaa gacgaactac ttgcagaaat tgaaaaatac aatcaagatc ctagttttca
      361 tggtatattg gtccaattac cattgccaaa gcatatagat gaagaaaaga tcctgttagc
      421 tatccgccct gaaaaagacg tagacggttt tcatccgatg aatttaggca gactccttgc
      481 gggtaaaccg gacaagattc cttgtactcc atacggcatc atgaaaatgt ttgaagctta
      541 ttctatcgat ccggcgggta aacgagcagt agttatcgga cgaagcaata tcgtcggtaa
      601 accgatggct cagctactct tgatggcaga tgcaactgtt actgttgctc attctaaaac
      661 cgaaaatctg gctgaactgg cacaagaagc agatatttta gtcgtagcaa taggacgtgg
      721 acattttgtc acaaaagaat tcgtaaaacc aggtgctgta gtgatagatg tagggatgaa
      781 tcgtgatgct aacggtaagc tgatcggtga tgtgaaattt gatgaagtgg agcctattgc
      841 aggctggatc actcctgtgc caaagggtgt agggccaatg actatcacga tgctgatgta
      901 tcaaaccgta aaatctgccg aagcttttgg agcaggtgaa tagatggcac aagaatattt
      961 aactgtcact acattaacga agtatttgaa aagaaaattt gatgccgatc cttatttaga
     1021 acgcgtatat ttaacaggcg aaatatcgaa tttccgttta cgtgccaatg cccatcaata
     1081 tttcagctta aaagatgacc atgcaaaaat atctgctatt atgttcaaag gagcattcca
     1141 aaaattacga ttccagccaa aagaaggaat gaaagtcctt gtcgttgggc gtatttcatt
     1201 atatgaagcg ggaggttctt atcaaatcta tgtagagcac atggagcctg atggaatagg
     1261 tgctttatat caagaattgg aagaacgaaa agaaaagctg atgaaggaag gcctttttca
     1321 agggcctaaa aaaatgctgc cacgtttccc aaagcgaatc gcggtcctta ccagtccaag
     1381 cggagcggtt atccgcgata tcatcacgac ggtgaaaaga agatatccaa ttgtccaatt
     1441 ggttttgttc ccaacagttg tacaaggaaa ccaagcagcg gacaatgttg tcaggaatat
     1501 ccagagagta gaagagatgg gcaatttcga tacaatgatc atcggtcgtg ggggtggttc
     1561 gattgaggat ttatggccgt ttaatgaaga gcgggttgct cgggcgattt atcaagctaa
     1621 tacgccggtg atttcatctg taggacatga aacagatacc acgatcgctg atttagtagc
     1681 agatgttcgg gctgccactc caacagcagc tgcagaatta gctgttcctg ttttgtcaga
     1741 agagttgatg cgcattcaag aacggcaagc tagattgcag caggcgtttg tacgccagat
     1801 ccagcgcaaa caagaacggt tcgagcgtgc tcgacgttcc tatgtatttc ggcagcctga
     1861 aagattgtat gaaggtcaga ccatcaaatt agaccagttg aaacagcgat tatatcaagc
     1921 tacacagcaa atttatcatg cgaaagaaaa acaaacgatc gcattaagcc accaattgga
     1981 acaagtggct ccgctttatc gagttaaagc agctcgccaa gaaactgctt atctagaaaa
     2041 acgcttagaa gagaaaatcc aacaatatat gaaacaacag cagcagcgtt ttgctcaagc
     2101 tgttcaatct cttgatttgt tgagtccatt gaaaatcatg ggaagaggct acagctatac
     2161 gacgttaaat gatcaagtag taaaaagtgt caccgagatt catcaagggg atttgctgac
     2221 gatccattat caagatggaa tcgttaaagg acaagtacaa gagatagaca aaggagaata
     2281 aaaatatgga aaatccaact tttgaagagt cactgcaaga attagaaaaa attgtcatgc
     2341 agttagaaca aggagacgtt ccattagaat cagctctaga ttcgtttaaa cgaggaatgg
     2401 aattaagcaa acattgccaa gatacattag ctaaagcaga agagaccttg acgaaaatga
     2461 tgacagaatc aaatgaagaa gttgattttg acggaaacga ggaaagctga gatgagatta
     2521 actgactttt cagctattca tctacctgct gtagaaaaag aaatcttgtc ttttttagat
     2581 gagcatacaa cggatagagg actctatgat gcgatgagtt attcagtgaa agcaggcggg
     2641 aaaagaatac gtcccttatt acttttaacg gccgttgctt cctttgatga gcctattgat
     2701 gttcccgtct atcaagtagc agctgcttta gaaatggtgc atacgtattc cttgatccac
     2761 gatgatttgc ctgcgatgga caatgatgat cttcgtagag gaaaacctac caatcataaa
     2821 gtattcggcg aagcattagc tatattggcc ggagatggtt tgcttacagg agcattccag
     2881 ctaatcagta tggcacactt aggtaattct cctaagcttc tgctgcttca gcaattagct
     2941 gtttgtgcgg gatcacaagg tatggttgct gggcaagctg cagatatcga gggcgaatcg
     3001 aaaaagcttt ctttagaaga attagcattt attcatgaaa gaaagacagg gcatttgatt
     3061 cgttatgcct tgctggctgg tggcatatta gcgaagcaac ctgaagaaat cttattgcta
     3121 cttcaacgat tagccgaaca tttaggttta gcttttcaga taagagatga tctactcgat
     3181 gtgattggta caacgaaaac attagggaaa acagctggta aagatgaacg tatggaaaaa
     3241 aatacttacc cgcgtttatt aggcctagaa aagacacgtg aggcgttgga gattgagctg
     3301 ttatccgcca acaagatcat agacaaatta gaagaggacg ttttttcttt tgatggcggg
     3361 ctgatgcgcc agatgatcaa gcaatttgat gtggagaaat gagggaaaga atggaaaaag
     3421 aacgcgtaga tgtattagcg gtcaaacaag gattatttga aacaagagaa caagccaaac
     3481 gttcagtgat ggctggtttg atttacaacg aaaaaaacga gcggtttgat aaaccgggag
     3541 aaaaaattcc agtgagtagt gaattaagag tcaaaggtaa aaaacttcct tatgtttctc
     3601 gagggggatt aaaattagaa aaagcactca aagcatttga tctatctgtt gaaggaaaaa
     3661 cattgttaga tattggtgca tccactggcg gatttactga tgcagctttg caaaatggcg
     3721 caaaaatgag ttatgcttta gacgttggct acaatcagct agcttggaaa ataagacaag
     3781 atcctagagt cgtcgtaatg gaaagagtga attttcgtta tgcaaaaccc gaagacttta
     3841 ccttaggaat tccagaagtt gctgttatcg atgtttcttt tatttcacta aaactgatgc
     3901 tgcctccatt acatgctatt ttaaaagaag agggagaagt gattgcttta atcaaacccc
     3961 aattcgaagc aggcagagaa gctgtaggga aaaacggaat tgttcgtgac cctcagaccc
     4021 atcaaaaagt tttagaagac attttgtcat ttgcggcaca aggtggatat gatgtgctgg
     4081 aattaagtta ttctccgatc acggggggag aaggaaatat cgagttcttg gctcacttga
     4141 ggaaagtacc cgaaagcgga acaatcaatt cagctattaa tatggcagaa gtggtttcaa
     4201 atgcacacga acagtttgac cataaataaa ttgtaactgt gaaaatcaag tgagaagtat
     4261 gcggattctt ctttattata ccaaggaaat aagctatcat tgattaagaa gaatatgcta
     4321 aggagcgaag acgtaatgag aaaaaaagat cggcatcgtt tgattactcg attgttgagt
     4381 gagcaagata tccgaaagca ggaagaattt gttgaaatcc tgaaaagcaa aggaatatct
     4441 gttactcaag ctacgatttc cagagatata aaggaactga aactgatcaa ggtaccggct
     4501 tcagatggcg gctaccgtta tagcatacca gctgaaacaa acgaagatgt aaatactaaa
     4561 ttggaaaaac tattaaaaga cgctttcgtg gcagttgacc aaatggaaaa atttgttatt
     4621 ttgaaaacat tgccgggaaa tgcttcggca gcagcaaatt tgattgataa acgttacaag
     4681 aaagaattat tttcgattat caatgatgac gataatgttt tgatgattac acgaactgaa
     4741 gaccaggcag ttttattgaa gaaagacttc ctgcattacc tttaagttga ggagcgaatg
     4801 tgatgctaca agaaatcagt attactaact ttgcgattat tccggaattg cggctttctt
     4861 ttcacgaagg aatgaccgcg ctgaccggag agactggtgc gggtaaatcc attattatcg
     4921 atgctttagg tctgttagca ggaggaagag gttcaagcga ttatatacgt caaggagcag
     4981 aaaaatgtgt gcttgaaggg ttgtttgaac taccaaaaca agaaggattc tctgaactga
     5041 tggttgaatt agggatcgaa acagatgagg acaatctgat tgttcgacgg gatatgtcct
     5101 taactggaaa aaatgtttgt cgagtgaatg gtcatattat cacattagct aatctgagaa
     5161 gaatcggcag ttatttagta gatatccaag gacaaaacga acatcaggaa ctgctccagc
     5221 ctgaatcaca tcttgcttta ttggatcgtt ttggagatgt agctttccaa cagaagaaaa
     5281 agagttatca gcaagaatat atctcttatc gtgagctgga aaaaagggta cgaaaagtgc
     5341 agcaaaatga aaaatcctat gttcagagaa tagatatgct ccatttccag caagaagaaa
     5401 tagctgctgc tgatttgcaa gtcggagaag aagagaaatt aaaagaagaa agagaaaaac
     5461 ttagcaatta tcaaaaaatt gctgatggat tagctgcagg ttacggagca ctgacgaata
     5521 atgaacaaaa cagtgtagat ggtgttggct tggccgtttc agaactgcaa gggatcgccc
     5581 atctagatgt ggagtatgaa gcaatttatg aaaatatcca aagtgcttac tatttgctgc
     5641 aagatgcaat cggcgatatg agtcgtcaga ttgatttatt ggagttagat gagagtcgtt
     5701 tagaagaagt tacgcaacgt ttagaattaa tccgacagtt gaaacgtaaa tacggcgaat
     5761 ccattgagtc aatattggct tactatgacg aaatcaccga agagctagct tcttctgatt
     5821 tttcagaagg tcaattggac aaaatgaaag aggaactaga gcaaaaagag cttctacttc
     5881 agcaacaagc cgcagatctt catgaagcgc gtaaaaaaat cgcaaaagaa ttggaaaaat
     5941 ccattctgca tgaattgaaa agtctgtata tggaaaacac tgagtttgag gtacgtttct
     6001 taaaagaaga aaatagacaa ttgaatcatg atggatttga ccaaatcgaa ttttacatta
     6061 cgaccaatcc aggagagcca ctgaagcctt tggtgaaagt cgcttctggt ggcgaactgt
     6121 ctcggatgtt gcttgctttg aaaactattt tttcttctga gcaaggtgtg acaagtatta
     6181 tttttgatga agtggataca ggtgtgagcg gaagagttgc acaggccatc gcagataaaa
     6241 tttctcaaat atcgaaatac tctcaagttt tgtgcatcac tcatctgcct caagttgctg
     6301 cagtcgccga ctatcaatat tatattgtga aagcagtgat tgatggacgt acgcaaactt
     6361 ctgtttcaga gttgaaaaca aaagaaagag aagaagaaat tgcacgtatg ctggctggaa
     6421 gtgagattac aaaactcaca ctcgaacatg caaaagaact attgaaactc gcaaaaagga
     6481 cctgagccac ctcgcagtgg ttcaggtcct tttcagcagc tgatagctat atttt
//
LOCUS       DAZKNV010000101         6437 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000101 DAZKNV010000000
VERSION     DAZKNV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.104"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            40..897
                     /locus_tag="ACG8M1_002648"
     CDS             40..897
                     /locus_tag="ACG8M1_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0423302.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            917..1477
                     /locus_tag="ACG8M1_002649"
     CDS             917..1477
                     /locus_tag="ACG8M1_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HFQ0423303.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2532..3299
                     /locus_tag="ACG8M1_002650"
     CDS             2532..3299
                     /locus_tag="ACG8M1_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HFQ0423304.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3325..3870
                     /locus_tag="ACG8M1_002651"
     CDS             3325..3870
                     /locus_tag="ACG8M1_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423305.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3871..4437
                     /locus_tag="ACG8M1_002652"
     CDS             3871..4437
                     /locus_tag="ACG8M1_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423306.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            4452..4700
                     /locus_tag="ACG8M1_002653"
     CDS             4452..4700
                     /locus_tag="ACG8M1_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423307.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4720..4959
                     /locus_tag="ACG8M1_002654"
     CDS             4720..4959
                     /locus_tag="ACG8M1_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423308.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            5330..5611
                     /locus_tag="ACG8M1_002655"
     CDS             5330..5611
                     /locus_tag="ACG8M1_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFQ0423309.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            5601..5942
                     /locus_tag="ACG8M1_002656"
     CDS             5601..5942
                     /locus_tag="ACG8M1_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0423310.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
BASE COUNT         2397 a          896 c         1292 g         1852 t
ORIGIN      
        1 ataaattgct tgaagtatta tatttagata tcataattta tggaagaaaa attaattaaa
       61 aaggatgaga ttataatggg gttactggtt ccgagagcta atacttatac tataccttta
      121 acgaaacgcc aattaattgc taaaagatat caaaggatta ctagagccat caatagagag
      181 ttttggaatt ctgaaagtga tactgctcac agtttatacg taggttctta tgggagagga
      241 acggcaatta gtactagtga tatagatata atagttgaat taccgatggc agaatttgac
      301 agattcaaaa attatttatc aaatggcccg tctaagttat tacaagttat aaaaaacgca
      361 tttcaggaaa tactaccaaa tagtgatatt agagctgatg gacaagttgt taaaataaat
      421 ttccatgatg gaatcaaatt tgaaatagtt ccagctttta atgaaaaaga ttattggggt
      481 gagtcaaaag ggtttattta tccagattca aacatgggag ggaactggaa agctacaaat
      541 cccaaaaaag agcaagaagc catgaaatta aagaatacaa aaagtaataa tttattatat
      601 gctacgtgta aacattttcg acatgtacga gatacagaat ttacgagtta tcatctttca
      661 ggaatagtaa ttgacagttt cgtatatgag gctatgggaa attggaaatt cgttgaaaat
      721 aacagtgggg gtcaaaacat tagttctgta tcttatgaga cagctttatt agaatactat
      781 aactcacata aagttatggg cggtttaaat ttatactctc ctggaagcaa tcaatttgtt
      841 aattctgata gtagtatcat atgtttagaa aaagtattaa aaaaaatagc tttataaagt
      901 tttatggagg aacaacatgg gagacgaaaa aaagcgcttg gaagttcaat tacgtgaagc
      961 atatggacga gtaacgtata cttacaccac tcatttaaag caagccgata atattatttc
     1021 tgacaataaa attttaaggt gtcttcaaat tggtttgtca gcccttacta ctggaggggt
     1081 acttagtacc attattactg ataatagtga gttaaccttt gttgctggat tatgttcaac
     1141 aatttctctt ggattaaact tatactttaa gaactttgat cttgctgaag aagctaaaaa
     1201 tcatcaaatt gttgccgata aattatggtt gatcagagaa gaatacgtaa gcttactaac
     1261 agatttaaat cgtttaagtg ttgaagatat tgtgaaaaaa agagatcaat taatgaacga
     1321 aactcatgaa gcatataaaa atgcccctaa aacaaatagt aaaagctatg aatcagctca
     1381 gaaagcatta aaatctgaag aagagcaatt ttttacagaa gaggaattgg ataagatgtt
     1441 accagagcat cttagaaaaa agagttctaa atattgaact ctttttttat gcttaaaatt
     1501 ctcttgtaat ttttctattc aatcaataaa taatctatat ttaagaagaa atatgatgat
     1561 agaaacatct cctgaagcca ccgcaagccg ttctaagcat agcttagccc gacattgcta
     1621 gatatgctca tctcaccatg aacgtttcct aaagccaccg caagccgtcc tagccattgc
     1681 ctagtccgac atcgctagat tagtgcatct cgccataaaa gttttctaaa gccaccgcaa
     1741 gccgttctaa gcatagctta gcccgacatt gctagatatg ctcatctcac catgaacgtt
     1801 tcctaaagcc accgcaagcc gtcctaagca tagcttagcc cgacattgct agatatgctc
     1861 atctcaccat gaacgtttcc taaagccacc gcaagccgtt ctaagcatag cttagcccga
     1921 cattgctaga tatgctcatc tcaccatgaa cgtttcctaa agccaccgca aaccgtccta
     1981 gccatcgcct agtccgattt tgcttgatcg gttccatttc tgtttattta gtgggtcaac
     2041 accgtaatct taaatagcca tcgcctattt aagattacta ggtctgcttt gaaggtaaaa
     2101 agtctttcat tcttcaagac ttttaggctt tcaagctacg cctgaaagca ttgaaattca
     2161 tcgctcttta tttggttttg ccatttataa ttccttacgc ccattatctt tttcgcctgt
     2221 cttgccttgt cagaagtgtt tagagcttat ctcatctttg gattaataca agtggcgtaa
     2281 atttttttct aaacgcaagc gttacgaaaa taatttactt aaacacttgt attaatccgg
     2341 cagataagaa cgcattctaa tcactcccga caaggcaaga caggcgaaaa agataaataa
     2401 atgaacgaaa ggaagaaaca taaaatgcaa aaccaaatag cgatgaagaa aaaaccacct
     2461 ccctctaaaa caatccaaac aaaaaagaat tttgaaaaac caaaaatcaa aaacagaaag
     2521 aagcgttcaa catgagagat agaattttag aagttaatca agaaatggta aacaagttaa
     2581 caaatatcag tgggaactat gaaaagtacg atggtacttt acttgataac tatatttttc
     2641 acgatacaca aaatatcaga attggcagaa gtaaaccgag agcgttcatt ctcatcaaag
     2701 agaaatattt gaatgaatgg aatagcacct atgaaatggt tatgactgat aactttgaaa
     2761 aggtattgga tttcagaaat gctttgttgg gttctgatat gggaaatagc agtcttgaat
     2821 ctattgaagt tgaaaacaag accgagaatg aaggtgaagg attgattaag aatgtcttga
     2881 aaatcgaaca aaaatatatc agtgaagata gaagttttta tagagtcaca agctcggttg
     2941 gtctagcaaa ctttgctact aacttaattg gaaacaatgc tagtgaatct ttgctagtga
     3001 tgtgtctgaa tacaaagaat gaggtcattg cttatagcga agttttcaaa ggtggaatta
     3061 atcaatcagt agcgatacca agagagattt ttcaactagc tttgctaaac aattcagcaa
     3121 aaatcgcagt atcacataat catccgagcg gatatgaatt tccaagtgaa aatgacaaaa
     3181 gttttactac gaatttgaaa aacgcaggaa aaacaattgg tattgaattg ttagaccata
     3241 tcatcgtaac aagtaaaaac acaagctatt actcatttca agaaaatggt tctttataaa
     3301 aattagagaa aagaggaaaa caagatgggc gaaagaacac aagcgttaat tacagtcaaa
     3361 tatggtaaca gcaaaacgaa agcaagcgtg tcgattcatt atcagtgggg gtatggtcga
     3421 tatatgctga tggacgtatt gaatcaagga atttatttaa tcaataaagc atacgactta
     3481 cgagataaat caagagaaga attagcaaaa ggaatctttg atagaagtac aggagttatc
     3541 aattttgtta cctatgaatc tggagtgagt gcttatgatg aaacagggtt tggtgggcgc
     3601 tatgaacctt atcaagaaac gattgaagat gtgatgaagt tttcagataa caatgatggc
     3661 tatgctcatt tagagatggt gttcgatgaa aatggattta gtctagatga taaaaccaga
     3721 ttgcgattgt ttgattttga gggtcaacag ataggactaa acaagttttg tgaaagcgga
     3781 aaagagtttg ctacgaaaga ttttattaag ggatacagat tattgctaga aaattatgga
     3841 ataaacctag aagaagagag cgtgaaataa gtgtttgaaa aaagaaaaga ccagttccct
     3901 aatttagaag cgaaaagtca aaaagtgatt gatggtgaaa tgattgaatt attccaaaaa
     3961 agttatggaa ccatagaaac taccgcaagt tgcaaatact actttcaagg aaagagaaac
     4021 acgtttaaag gctttgccga ttctgatgaa gaattggcaa agaaaatcat tgattggctt
     4081 gtcagcagtg aacacgtagc aagagaagat accgttagaa caacgattaa tggggaagtc
     4141 ctaacaggta ctagatgtgt ttgttgtaat catgaatttg tagaagatga aggttgctac
     4201 cgaatcaatg aatatggtga ttttatttgc cagagttgcc acgagataga atttccaacc
     4261 gaaagaagtt ggtttgaata catgctacaa gattatgaga tggaaaaaga aaatggtgaa
     4321 gtagtttttt gtaccaaaga ggaattgagt aagagaagcg atgatgaaat tgaagattgg
     4381 tgtgtgtggt tagtaggggc agatgattgc gttgcatatt acacaacagc agaataggag
     4441 tgtgaatcag catggaagga atggattttc tagatcatga agatttggtt gattttggtt
     4501 atacatggaa aggaatggta ggtattagca gaagtcttgc taatgccttt tacgaaagaa
     4561 attatgcagt atatgttctt tatgatgacg atacagaaag ccttgttgac gaggaatata
     4621 aattggattt agagaatgtt ttatatggaa tagaaaagga agatttagca aaatatattt
     4681 tttcatggtt gggtcaataa gtgaaaggaa gatagaaaca tgacaaaatt taaaagtaag
     4741 ggtatgcaat ggtgttctta ttattatgtt ggaaatgatg aagatttatt gagaaaaacc
     4801 caacgaaaag gttatccaga taagatattg aaacaaatag gttattacat gccagaagag
     4861 aggatagaaa aagaattttg tgaggttctt tttgatagtg aacagctatt agttttgtta
     4921 acccaaaata aattgatttg ccaatttgaa aataattaag atgaggtggt gaaccatgaa
     4981 tgaagataag atggtattaa gtgaatatgc tagattgaga actattaatt ctttagcatc
     5041 tcatttaagt tgttctttcc taacaaaggt gctaaaatta atttacaaat gtgaagattt
     5101 tgtacaagag aagcacaaag acaagcctac tgcgaatagg cttgtctttt tttcattcat
     5161 tacgattccg tatgtgtggg ttagcgacaa tttgttcaat taccgtatga tatagcatct
     5221 taatttgatt agattacttg caatgtagtt tattaagagt ataatataat cataaatgtg
     5281 gacaatttga gaaataatga gtgttttata ctcaaaagga gtggatgaaa tgaaggtcaa
     5341 aaatccaact gaaaaaagca gaatccaagt cggaatagac aagaatttaa aagagaacgc
     5401 agaaatgata ttggaagagc taggtttaaa tcctacaaca gcaataacaa ttctttacaa
     5461 acaagtagtc gctagaggtg agtttccagt agagataaag ctaagtgaag aggagaagca
     5521 aggaatcaga ttgcaacagc taactaagga catgccagta gatgttctag atacagatga
     5581 aaagttagaa gagtggttcg atgaagccta atgagatagt aacggtctat gttgcattta
     5641 cagataaaaa tggtggtaaa agaagaccta ttttggtggt tagtgataaa gaagatagag
     5701 tagaattctt tggaatcaca agtcaatatg agaaaaaatc agaccaaata aagagggtgt
     5761 attttcctat tgcagaatgg gaaaaagcag gacttaaaaa gcaatcatgg attgacgtag
     5821 ggtctttaaa ggctattccc aaaagccgag agaacatatc attcaaaaag gttggtatgt
     5881 tatcagctag tgatacgaaa aagctaaata ggtttatcga gaaattacaa agaaaagtct
     5941 aacaaggctt ttcttttttg tttatatgta tattaagata tacgtttata taaacgtatt
     6001 tatgtatatg aaaatatacg taaatatata cgtgattata aacattaaga aaacgttaag
     6061 aattgttaaa tagtgatatt tagtaatata cgaattataa gatatatttt atatagaatg
     6121 tatgtaaata aataaaatgt ctgacggata ttgaatagca ataaataaca ataattcaga
     6181 cggatacagt gagtgaagta gcttgctacg aacgaacagg cagaatgaaa cggcagtttc
     6241 attagagcaa gtcgcttgcg acgtagcgtt accgctgatg taactggcaa gttacataga
     6301 gagagtttgc ttgcaaacga acgttaccta cttgaataga aataaaaaat aacagattag
     6361 tgaattttga ataggagcca caactcaacc aaccgcttgc ggtgggtgag tcccacggag
     6421 gaaaagacga acgaacg
//
LOCUS       DAZKNV010000102         6329 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000102 DAZKNV010000000
VERSION     DAZKNV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.105"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACG8M1_002657"
     CDS             complement(99..1229)
                     /locus_tag="ACG8M1_002657"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFQ0423311.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACG8M1_002658"
     CDS             complement(1878..3080)
                     /locus_tag="ACG8M1_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0423312.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACG8M1_002659"
     CDS             complement(3140..3343)
                     /locus_tag="ACG8M1_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFQ0423313.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACG8M1_002660"
     CDS             complement(3485..4552)
                     /locus_tag="ACG8M1_002660"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0423314.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACG8M1_002661"
     CDS             complement(4610..4717)
                     /locus_tag="ACG8M1_002661"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423315.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACG8M1_002662"
     CDS             4880..5692
                     /locus_tag="ACG8M1_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423316.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACG8M1_002663"
     CDS             complement(6066..6257)
                     /locus_tag="ACG8M1_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423317.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         1885 a         1300 c          997 g         2147 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaaca
//
LOCUS       DAZKNV010000103         6220 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000103 DAZKNV010000000
VERSION     DAZKNV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.106"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(733..1236)
                     /locus_tag="ACG8M1_002664"
     CDS             complement(733..1236)
                     /locus_tag="ACG8M1_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0423318.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1595..2620
                     /locus_tag="ACG8M1_002665"
     CDS             1595..2620
                     /locus_tag="ACG8M1_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0423319.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2943..3821
                     /locus_tag="ACG8M1_002666"
     CDS             2943..3821
                     /locus_tag="ACG8M1_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFQ0423320.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            4297..4413
                     /locus_tag="ACG8M1_002667"
     CDS             4297..4413
                     /locus_tag="ACG8M1_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFQ0423321.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            5341..5679
                     /locus_tag="ACG8M1_002668"
     CDS             5341..5679
                     /locus_tag="ACG8M1_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423322.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5773..6003
                     /locus_tag="ACG8M1_002669"
     CDS             5773..6003
                     /locus_tag="ACG8M1_002669"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFQ0423323.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            6017..>6220
                     /locus_tag="ACG8M1_002670"
     CDS             6017..>6220
                     /locus_tag="ACG8M1_002670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423324.1"
                     /translation="MKNFDTYYVIVFSISLLLILLTLMQYKEYPEYFILTFVYLVSSY
                     TLLYKFRSSSRVSKVCFLISLLIL"
BASE COUNT         2125 a          916 c         1133 g         2046 t
ORIGIN      
        1 tatttgtgga aaatttaatt tttagaaaag tgtatcgaaa aatagatagt tagtttttcc
       61 acagtggata acttcgtaag agataaaaat aaaaaattag tcaaagaagg gcgtatagat
      121 ttcttttgat aggagatata caacagaaat gaataaatat taacgtgttt tcaaacagta
      181 taaaacggtg tggtttttgg aataaaaaaa taacatatct cattttacac ttttgttatt
      241 ttatacttaa aaaataacga cacagaaaat accgtgtctc agatttctct actacttcta
      301 aaaactactg tttttttcct ttgaaatgcc ttcaaaaagt aggatcaggc agaatatact
      361 ggcagaatca aggagaaggg agcctaaata aggagaaaaa ccatagaaaa tataaagtaa
      421 ttacttataa aacaagcttt ttatagaaaa ataatatacc tgagtagggt ataaattaag
      481 acggaattcc tttctagatt gagatattga ctaggaagaa tgttaagatt ttaagccttt
      541 aagctaaaaa aaaacccttt ttgttaaata aggggaatat agcctgtcag tttcaaactg
      601 caagtcgtcc tgctgcaata atatagtaga ttagagatga aaatagattt ttttaaacca
      661 atgactgaat aaaaagaccg tcatagatac acattggaat gtgtctatta cggtcttttt
      721 ttacgaacga ttttattgaa gacggacagt tcgggtcaaa aataaaaaag ctacgatcag
      781 aaataagaat aaaatgtatc ccaaaataat ggctagacgg tctaacttat ttgtcgatag
      841 atgtttgttt agaagttgat aggcccataa acctatcagt cctcctgttg tattagttat
      901 caaatcagtg atgtccgcta cgccaatacc gaataggaat tgaatcaatt ctgccaagaa
      961 gcttacaagg aaaataatcc ctaatttttt agaaaaagaa agtctcttga aattgacatt
     1021 caaaagcacc ccaaaaggaa aaaagacaat caagttataa gtggtctcac gtaataccgt
     1081 cgtattttca aaagaaaaag tagaaaaagg gacgagattg acattgctgt aagaataagt
     1141 gagaaattgt ggaagattaa atgatagctt gaataaaatc aaccataata gaaagaataa
     1201 ataaatccct aataaaaatt ttgatacata ccgcatagac atctcctcca tttaaaaagt
     1261 ataccatcga aaaccgctga aaaatcataa aaaagtatga agtttaagga ccaacgtagt
     1321 tatcgtacga aaattagaag cttttttttg ttgggaatcc ggtttcttta acaaagctaa
     1381 gatagcgagt tgcttggaaa agttgctatc ttttttctgt caaaacgact cggaatgttc
     1441 gttttttgtt ctaatttctc caagttgttt actttttgat actaagttta tgaaaaatca
     1501 agaaatagtt gttatactag gtaatgctga caaacgggat tggcatttca tcttggttca
     1561 gctttttttc caattactag gaaggaggga tagattgttc aagacttatt ttcgtttcaa
     1621 taaaatacaa gataatcctt ttcgtatcat gaatctgatg ctacttatct ttattgtatt
     1681 atggttaggt tacataaatc atgatttttt gatttcaagt ttttcatcat tagggatctt
     1741 tacttttttc tattatcaaa acataccgat gaaatatttg ctgaaacgta tgtttctgat
     1801 cggttgcgga ctgttggttg ctttcgtttt ggggatctta tcgacttatg ttttatggct
     1861 tgaaccattt gccgtagctt tggttgcttt ttccagcaga ttcgtgttgc gattattcca
     1921 tatttctaaa ccaggtggct tgttttttgc gatgctttct gccatgggaa cgagcatgca
     1981 gctgccaatc gctcaattac cgatcgtctc actttatttt tttatgggtg tcgtttttgc
     2041 cctgattgcg gcagtgatta caaaattact ggattcacgg cctgagcaga caattgaaaa
     2101 agcaacttta aaagaaagat ttcacgaaga gcctttagtg atcattgatt ctgttttcta
     2161 cagcgctgcc ttatttcttt ccgtttatgt cagtcacggc ttgaatctgc ataatcctta
     2221 ttggttgacc ttgtcatgtg catcgatttt gctagcagaa aacttggatg cgatgaagca
     2281 tcgacaagtc caatatctga ttggatcgat gggtgggtta tgtgtgtcgg cattcttgtc
     2341 atttgtgccg tttacgcagt tgcagaccat ttttctgatc acttttctat atggaatcgc
     2401 acaatttcta gttgctagaa attatgcagt tgctaatatt tttcttaatc cgatggcgtt
     2461 gatgctatct acacttattc gtggagcata cttgatttct ttgatcgaat atcgtttttt
     2521 agggatcgtc ataggaagtt tcatcggttt aggtgttgcg tgggtaatga cggttggttt
     2581 gcaacattat ttaacggttg ttcgtcaaaa attagaatag aaggacaaat atatgtgcca
     2641 aaagaggtta tgacaagatt tttgtcacaa cctctaattc aaggtgttca aaagccagat
     2701 tctcagcatt aagtcaaatt cacacaaaaa tgtggaaagg aactttcaaa aaaattttat
     2761 atttattcta tcaaaaaatt ttgtttatga tggtaactga ataaactttc ctgagatggt
     2821 caatgctttc cttgaaagtc ttacagatat tctttcttca tagaaagttt aagttttata
     2881 gttagtgtac aataaaagta tgtttatacc atatggtgtc cggataatca gtcatttaaa
     2941 caatgaggtt caaagatatg aaaaggggaa atttgatgaa gaaaataagc aatgaaatcc
     3001 aaattctggc agaaacttta actcttccca aagtcgttat agagcaaatg attgtacaag
     3061 caaaaaacat ccttgatgag gtgtttgagc aatatagtca tgaactaatg gatcctaata
     3121 aagcaaaggc gactgcaaag aaaatagaca aagtctatga agaggaacct tttgcagcat
     3181 tagctattta tctatatgca gcttctcaaa gttggaaaaa aatttatcaa ccattgaaga
     3241 ttccaagaac tatctatttg gcaacaatga atgcttttac tagatttatt catgaacatt
     3301 tccaagtaac aggaagctat cgctttgacc gtggtttttg gatttggcat tacactagtg
     3361 gcttgatctt tcggattggt gaattggagt acgaaatgac atattttccg aaagggtaca
     3421 cggatctaag attagaagga aagcagtgcc tttctcttca tattccttcc gatgcagatt
     3481 tatctcagaa taagataaga gatagttacg aaagtgccat tcgttttttt gaactttatt
     3541 ttcctgatta ccattaccaa gtgatgtaca cagatacttg gttactatca cccaatctta
     3601 ctaaatggtt gaaaaaagag tcaaaaatct gtctttttgc agccgattat cgattattat
     3661 cagttgatga acaggacgat agtggagtcc cttggatctt tggacgagta gatgcccaaa
     3721 tacatgatta tccagaaagt acgagtttac agcgacaagc aaaagagcaa ttgcttgcag
     3781 gcgagcacat tggctctggc ttaggtattc ttacttcata agtttagtac ttcgaaatag
     3841 tttaaaagag cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata
     3901 aacggcggaa gcagaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa
     3961 gcaattttcg tgaatttctt cttgtttctt ggagttaaac gcttctgtcc cagcctcttt
     4021 tttagtgttc tatcgaacac acagtacgtt caataggtaa actagctata acaatagata
     4081 ttaaagttaa cggacaagag ggcctttttt aggtagctaa aacgtaataa tgaaaattta
     4141 tttccagaga taggagtcaa tcagctagtc tgatcgactg ttttaacaag ttgactttca
     4201 ttttaacttt tgataccatt taaaacacaa atcgtaattg tttcgatttg tgttttttag
     4261 catgactaca atcaaagaag aaagtgggtc gtccatatgg aaaaaacaga tatctcaagt
     4321 gcataccgcc gcttgaaaag cccaaatatc aaaacacgaa aacgtgcgct gaagatcatc
     4381 aaagatgtga aacggaatag tgggaaaagg taagaagaag gaaacttaat taaaaaaata
     4441 gccgaaaaac gtttttcggc tattttcaat aatcggtttt tgtgtaaggt ttccgaaaga
     4501 actgctgttg attttccatt tttaacatat gataaattgg tagaatcttt cttttcaaat
     4561 tgataccatt ccctaattcc agttatatag ttaactacag aaccacaaag cacgtacgtt
     4621 tataaaagta ttatctgtag ttatttttca attccctttc aacctcttat tttgaccagt
     4681 agtattgatc actttacctt ttaacacctt tgttcgtttt tgaaacattt ttagtcaaga
     4741 atggaaacgt aactacataa tcaaaggttt tgcgaaatat ttcatgaaat atttcatgta
     4801 gaagcgagca atacggttgc aaataaccat tatcgtttaa taagcagtta cgaaagctcc
     4861 caatatctct aacgttcagc tcactccatt tcttttcttc aaaaaaatca gtgattcgta
     4921 tctctttcta tttgtcgaaa aagttaactt taaaaagtaa cgccgaaaaa atatgcaaaa
     4981 aaataaaaaa gcagttacta ttgctagaat aacatcaagg aataataagt tttggttttc
     5041 agataatagt cgataagttg tgtattggaa ttttagatac agtaataaag tatttttcat
     5101 gaaattttgt gagaatcact attacaagta tctttaataa aattaatggt taaggaggaa
     5161 cttaaagtag aatgtaaatg aatagttgta gtcagtcgat tgtgatacta gactcaaagt
     5221 tgcaggaata agtttttcaa tttgtgattg gaagataaaa aatgaaaaag aagggctttt
     5281 ttttatactt tgttgattgt agtgtttatt ttccctctgt ttagccaagt aacattttct
     5341 atgactcaac cagtttcaag tgaggaacat gataaccttt ttcgtgctac agaagagttt
     5401 aagaaatatc aggaaaatat tgttccggag actccattag ctagtgagcc aattactgat
     5461 attgatggaa accaaatagg atggtatata cagtacgaag ttatggtggt aaataatgac
     5521 tcaatagtaa aaaatacagt aggcttagag ctaacaccga ttgaaaaggt gagttcattg
     5581 ttaacgtata tttatactga tgaaagtgac gagactgaga tcattttaac ggattactca
     5641 aaaattgcta ctgataaaaa gtatatattg tggatgtaga cactagtgaa atactttatg
     5701 atatagaaat tgatgaaaat ttactagatg tagcacaaga aatcgatcat caaaagcagg
     5761 aagctattcg atatgctggt agaaaaggga aaagaaaata tttattacgt gaatgtagca
     5821 aaagttagag aagatgaaaa tgagtggaaa gaattcaaga gtcgctactc aattaactcg
     5881 actccgacat ttacagttta cagagaagga tcgatagaaa aaactgtttt ttggactaaa
     5941 gaaagtggaa tgtctttagc tgaagtagaa gagtttttgg attatgttag tatgcaacag
     6001 taagggagtt cttattatga aaaattttga cacatattat gttattgttt tttcgatatc
     6061 tttgctgtta atattactaa ctttaatgca gtataaagag tatccagagt attttatttt
     6121 aacttttgta tatttagtaa gtagctacac acttctatat aaattcagaa gttcttctag
     6181 agtttctaaa gtttgtttct taattagctt attgattcta
//
LOCUS       DAZKNV010000104         6173 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000104 DAZKNV010000000
VERSION     DAZKNV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.107"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACG8M1_002671"
     CDS             725..811
                     /locus_tag="ACG8M1_002671"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFQ0423325.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACG8M1_002672"
     CDS             complement(932..1621)
                     /locus_tag="ACG8M1_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423326.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="ACG8M1_002673"
     CDS             complement(1628..1906)
                     /locus_tag="ACG8M1_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423327.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="ACG8M1_002674"
     CDS             complement(1866..2780)
                     /locus_tag="ACG8M1_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFQ0423328.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACG8M1_002675"
     CDS             complement(2762..3142)
                     /locus_tag="ACG8M1_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFQ0423329.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACG8M1_002676"
     CDS             complement(3592..3879)
                     /locus_tag="ACG8M1_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0423330.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACG8M1_002677"
     CDS             complement(3899..4123)
                     /locus_tag="ACG8M1_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFQ0423331.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACG8M1_002678"
     CDS             complement(4578..4748)
                     /locus_tag="ACG8M1_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423332.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACG8M1_002679"
     CDS             complement(4763..5296)
                     /locus_tag="ACG8M1_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFQ0423333.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACG8M1_002680"
     CDS             complement(5317..>6173)
                     /locus_tag="ACG8M1_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0423334.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1632 a         1151 c         1042 g         2348 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga atgactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAZKNV010000105         6073 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000105 DAZKNV010000000
VERSION     DAZKNV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.108"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            95..1123
                     /locus_tag="ACG8M1_002681"
     CDS             95..1123
                     /locus_tag="ACG8M1_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423335.1"
                     /translation="MYWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWIS
                     LLRISLQRMKQGHSITYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTE
                     QAYLYFMFGVMNTYLEEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLY
                     VNLAMIHLYSRVFGTKKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNT
                     YYEKNRRLIFQYCMLVRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYS
                     ASADQLPDIVISDYPIDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSI
                     LEKLDFVN"
     gene            complement(1149..1589)
                     /locus_tag="ACG8M1_002682"
     CDS             complement(1149..1589)
                     /locus_tag="ACG8M1_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0423336.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            1749..2255
                     /locus_tag="ACG8M1_002683"
     CDS             1749..2255
                     /locus_tag="ACG8M1_002683"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFQ0423337.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            2423..4336
                     /locus_tag="ACG8M1_002684"
     CDS             2423..4336
                     /locus_tag="ACG8M1_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0423338.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            4341..5342
                     /locus_tag="ACG8M1_002685"
     CDS             4341..5342
                     /locus_tag="ACG8M1_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0423339.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(5544..5750)
                     /locus_tag="ACG8M1_002686"
     CDS             complement(5544..5750)
                     /locus_tag="ACG8M1_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFQ0423340.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
BASE COUNT         2244 a          930 c         1204 g         1695 t
ORIGIN      
        1 tactattttg aaaaactatc atttatcttg cagcttgaaa aaaggtaatc cgatagaagg
       61 agaagaatac cgtatccgat acttttttca cttgatgtat tggcagtcat tcgacgaaaa
      121 tcattctgat atattatcaa gtataaaaaa taaacgtcaa ctattagaaa aatttgcgaa
      181 acatgcgcca tatacgcgta gtatagatag aaagaaatgg atcagcctac taagaatttc
      241 gttgcaacga atgaaacaag gccactcgat tacgtatgtc ccagaagaga tgaacaaatt
      301 tgtgcatcca ttgataacaa aagaagagtt tacgcattac atactagagc ctttttttga
      361 agcaaacttc tggtcgatga atcacatcac tccaacagag caagcttacc tttattttat
      421 gtttggtgta atgaacacct atttggaaga agatttgttg gatactccag ataaagtaca
      481 agaaagttgg ggctggattg aatcgtctat tgtagaaaat tttgaaaaaa acttcaagat
      541 ttgttttaca acttcagaaa aaaattatct atatgtcaat ttggcaatga tccatttgta
      601 ttcaagggtt tttgggacaa aaaagaaggt ggatgctttt ggaaaatcag cagaagacag
      661 agattttcag catatatttc cagtgatgta tccaatcatg caacagtttt ttagtggggt
      721 agctcgcaga attccagagc ttaatactta ttatgaaaag aacagacggt tgatttttca
      781 atactgtatg ttagtcaggg atatttttat aaaacacgaa caacctgtca tattctatat
      841 tcaatcaaag tatggtaaaa cacaggaatt atgggcaaag aaaaggatat tatctatgac
      901 tgaacgccca ataaaatata gtgcatccgc tgatcagtta cctgatattg tcattagcga
      961 ttatcctatc gacaaaaagg catatgatca aacgaataca cagatatttt actggaatgg
     1021 acaacctaca aaaaatgatt gggcgcgtct gaaagctgaa atcataaaaa tcaggaatga
     1081 gaaaaataga tccatattgg aaaaattgga tttcgttaat taagaaaagc agattgttta
     1141 tgccaaaatt aagacattgc aaaaagatta ttttctttaa aatcgacaag atgaccagaa
     1201 agcaagagtt cgttgagctc ttgctttctt ttagttttag aaaggaacat cctgatttta
     1261 tcttcgctaa atccagtcaa aagttttgca gattggtcgt agataatcgg ttttttcaat
     1321 aaagaagggg atgtacgaat ctcaatatat agttcactca aactgagttc atctattctg
     1381 tgaacaagat ttttataact aatagaatga gtagagagca tttcggtcac gccgttgttt
     1441 gtcaatttta gtaagtggat aaattcattt ttggttagtg gttgacgaat taagttctgt
     1501 tcgataaacg gtatatcatg gacgataagc caacgttttg cgcgtcttga agacgagcag
     1561 ccagaacctg tatacaattt aatcatcata cattcctcca atagctaagt atttatgaaa
     1621 taataacatg aagaaatagt cgaaaagtgc catttagagg tgtaaaataa gaaaatgttg
     1681 tcacgtataa tggaactagc tagataagaa atactattaa atcaagaaaa aagaaagaag
     1741 gcacaagtat gtcaaacaca gccgacgcaa tagtagtgat cgatttacaa aaaggggtat
     1801 gttttgattc ttcgccgata cacgaattag aaacagtgac agcattagtg aataaaagaa
     1861 tcaaaacata cgaaacgatt gggaaaccag ttattttcgt tcaacacgaa gatgctcaat
     1921 tagtgccaca aacaaaacca tgggagctat tgtcggaatt atctattcct gagcacagtt
     1981 attttgtgag aaaaacccat gcgaattcat tttataagac taatttgagt gttttattaa
     2041 ctgaattgga ctgtcattcg atcgaattat gtggggcaca agcagagtat tgtatagata
     2101 cgactgtgaa gtttgctcat ggattaggat accagcttat gatgtgtaga ggagcaacga
     2161 caacttatga taatcctttt atgaaagcaa aggaaacaat cgctttttac gagaaaattt
     2221 gggataaacg atttctgaca tttttggagc aataagttgt ttcttcgttt aaaaaaagca
     2281 gaatggatac tggtttatcc attctgcttt attacgtaaa atgagaaaat aatcctgttc
     2341 tatttttatg ggataaacca tttatttttt gtataaaaaa tgtttgcgtt tacatataat
     2401 tctcctagaa acataaaaag gagtgaatag cttgagaaca aaacaagtat taaagggagc
     2461 gttggtcatc ttatttgctg taagtacaag cgtcccgcaa tggacagtat atggagagag
     2521 catttcttcc gaatcggaat ctcgggaggt agaaaccaca gaaactactg atgctggaaa
     2581 tgaaacgaaa tcgagtactt cacaaacaga aacaaatact gaaacaacgg ttgagacatc
     2641 tgttactagc acagatcaag aaacgaccgc taccacagat aaccaacaaa cagaagaagc
     2701 aacagctaca aaaatgtcaa acgacgaatc ctcttctgct aaagtaagtg acaaagagaa
     2761 tgggacagaa aatgatgata tcggtaaagg tgaaaatttc aatggtaaag aatatttgaa
     2821 ttacttcggt aaacagatga cagaaatact taatggacca acagaagaca tcaagtcaaa
     2881 attaatagag ttattagtca ctgagcttgc tgttaatgat tatggtgtag ataaagagat
     2941 tatcaaacat ctgattgcta cttatctatt gtacgatatc gcttttgcaa aaaacagtgt
     3001 gttgatgtcg atgcttggag gtacagatga tgggacaacg cctacagaaa acacaggctt
     3061 ctatccaaat acaaaacaac ttcatcaaac tgtactaaac aaacaagatg gcaaaatgat
     3121 ggatgtatat gcatattatg tcgatcaagg ttcagataaa acagtcatga tccatggcgg
     3181 atttcgaggg aattggaata acgggatcgt tacagaagaa tacaatgatt tttataaggc
     3241 cgggtataat ttattatttg ttgattccag agcgactggt aatagcggag gcgattatgt
     3301 gacctatgga caatatgagt cagatgacgt cctttactgg ataaatcaag aagttcgaga
     3361 gcggccatct caaaagattt tactttatgg tggttcgatg ggagcagcta cgatgatgtc
     3421 tgtattagcg aaagatattc ctgtcaatgt caaaggaatt attgaaaatt gcggatttgc
     3481 atcaattgat gaacaactac gttttacgta cagccagaca gtagcccccg cactaccgga
     3541 tgccataaaa aatcagttag acatcattgg ggatcaagag catgaagatt tatttatggg
     3601 ccttttgaaa caatactatt ttgatcagga gatgcatttg gatacaaaag ctgctctacc
     3661 tacgattgga atgtcagatt cattgcctaa attgattatc catggaacag cagatgatgt
     3721 agtacctgtg tctaacgcgc aaaaattata tgagttatca ggagggtata aagatctttt
     3781 attagtagaa ggagcagggc atggaaaggc acaggaagtt gaccatgctg cctacacgaa
     3841 acatgtaacg gactttttga aagtagtgtt ccatgatcag ataaacgtaa agtatgtgga
     3901 tgaaaacaat aaaagtctac tcaaagacca ggacgaaatc cagctttacg gagcttatgg
     3961 agaaaattat atgacagagc aaaagacatt cgaaggatac gaattagcaa atgttgaagg
     4021 accgactgaa gggattttta atgagacgat accaactatt attttctatt acaaaaaaat
     4081 cccagtagct ccaccaaaaa agcaagatcc gacagagaat gcagacaata agggaaagaa
     4141 tgaacctcga gaggatcaat caagtgatga tacgcaaccg attcagatga cagtgaaagt
     4201 acaaaaaaag acagatgcaa aaaaaagaat gttgccgaaa actggagaaa agaaacattc
     4261 gcttctcatt tattcaggtg gatttttatc tgttagcacg attatcacat ggatttggcg
     4321 aagaaagaga gggtaaatga atgaaatggt tcaagcgaat agtgattgca gtaccagtta
     4381 tcatcgtagt tattttagtc actgtatttt tgattaatca aatcacacca aagccgatta
     4441 gcttgcttgt tagaaaacaa tttgacacaa gtgaaaaaga acaagtatat gcccgaccag
     4501 atgatttcca gcaaaaaatc gaacaaatcg atataaaaaa agaaatatcc tatccttcaa
     4561 agtacaaaaa taataatatg gatatctaca caccgaaagt ggaaaagaaa aaattaccga
     4621 ttcttttctg gatgcatgga ggcgcatatg taggagggga taaaaatgat tgtcgtgatt
     4681 atttggaata tctatgttca gacacgcagc aaatcatcgt aaatatagat tatgaacgat
     4741 caccggaagc aaaacatcct acaccagtta tccaattgaa cgaagccatt caagcagcta
     4801 aaaaagagat aaaagatcaa gcagattggt cgaatatttc gattggtgga aattcggcag
     4861 gtgcacaaat tagtggagaa tatttgttag cacttcaaaa tgaagaaatt aaaaaagctg
     4921 atcatcttga tccgactttg gagaacaagc agattacgaa gtttatttct ttgtctggtc
     4981 tgttggatcc ttctgcactt actcaagtaa gtgataaaat ctctagcttt ctttatgaaa
     5041 aatgtggatg ggcttacttt gataataagg actttgaaca atcagagaag gtcaaaagtt
     5101 tagccttggt cagacatgcg gatcgttgga cgcaaaacac attcttaacg gatggaaata
     5161 caaatacgtt tacgaaacaa atggaagaag taacttctgt atttgagaaa gcgggggtga
     5221 aagtcacaaa agtagattat gcggagaaaa atgctgtttt gaaccatgaa tatcagtttg
     5281 atttcagcaa taaacaagcg caagaaacat atcaaaagtt agtaatgttt ttcaaggagt
     5341 aaagtcttat gatgcaaaag aggttgtaat ctgtcactta gctccaagtc acaaggagca
     5401 atttcaataa acaagctttt catggtttat gaatattgta acttgtgact gaggagttag
     5461 agatggcaag gggcaccttt tattcgaaat ttgggaatat cacacgatta ttgtcacgat
     5521 ctcttttacg taaattttat aagtcagatt tgttgttttg atcgtttaaa aaaagcaaca
     5581 aatccgaagc ctgcggaggc aagaagggac aaaaagccga gtggtaagca aaagaatgct
     5641 ggttccacta atattccgtt gttattgata taaggctggg aacaaagatg aatagcaaat
     5701 aaaatcaatg cactagcgaa aaaaagcaaa gaaatatgga tagctttcat aagcagcacc
     5761 tcctttttta taattgtatg ataaatagat taagaatcta taaatgtgac aagtttgtta
     5821 ggatgtgaat aaaatgatca tctagcgaac ttgaaacaaa gatggctaat gataagcaat
     5881 taatgattca gcaatcagat aggtacaaag tttaccatca tacgtctaga ccaataatag
     5941 aaaatatggg aatataatag aaaagattta ggataccccc aaaagaattt ccccaaaaat
     6001 tcgatgtatc ctaaactttt ttattttaca taacaatcat atcaactgtg aaataaaatt
     6061 acaaatgata acc
//
LOCUS       DAZKNV010000106         6068 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000106 DAZKNV010000000
VERSION     DAZKNV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.109"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            439..645
                     /locus_tag="ACG8M1_002687"
     CDS             439..645
                     /locus_tag="ACG8M1_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFQ0423341.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            645..896
                     /locus_tag="ACG8M1_002688"
     CDS             645..896
                     /locus_tag="ACG8M1_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423342.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            911..1348
                     /locus_tag="ACG8M1_002689"
     CDS             911..1348
                     /locus_tag="ACG8M1_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423343.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            1341..2048
                     /locus_tag="ACG8M1_002690"
     CDS             1341..2048
                     /locus_tag="ACG8M1_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423344.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            2213..2413
                     /locus_tag="ACG8M1_002691"
     CDS             2213..2413
                     /locus_tag="ACG8M1_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423345.1"
                     /translation="MNKIIPLLFVLFVGEILMRHAAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            2429..2608
                     /locus_tag="ACG8M1_002692"
     CDS             2429..2608
                     /locus_tag="ACG8M1_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423346.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            2949..3212
                     /locus_tag="ACG8M1_002693"
     CDS             2949..3212
                     /locus_tag="ACG8M1_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFQ0423347.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            3206..3556
                     /locus_tag="ACG8M1_002694"
     CDS             3206..3556
                     /locus_tag="ACG8M1_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0423348.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(3580..4194)
                     /locus_tag="ACG8M1_002695"
     CDS             complement(3580..4194)
                     /locus_tag="ACG8M1_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0423349.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            4508..4930
                     /locus_tag="ACG8M1_002696"
     CDS             4508..4930
                     /locus_tag="ACG8M1_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423350.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            4940..5143
                     /locus_tag="ACG8M1_002697"
     CDS             4940..5143
                     /locus_tag="ACG8M1_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423351.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            5354..5938
                     /locus_tag="ACG8M1_002698"
     CDS             5354..5938
                     /locus_tag="ACG8M1_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0423352.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         2140 a          944 c         1157 g         1827 t
ORIGIN      
        1 aaaagaagag ttgtagtcct aaatgaggat tgcagctctt tttgttttac atagaaacag
       61 gaaaagacct ttttaggaag acacaagtgc cttctcaatt gaaaaacctt tctctcactc
      121 caaccgccac cgccgttcga gaagaaagga agtgaacgct gcacgttcac taagatatgg
      181 tgtcttgcaa agcaagacaa aatagacaaa acttcctctc accaaaaggt tcgttcctgt
      241 tcgttatctc tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc
      301 gacaaggaca agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt
      361 tattctggcc aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa
      421 gaggaggcag aatcaaacat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa
      481 ttattcccaa actatcatgc accacatact gttgaatgcg attgtggaga aagagcgaaa
      541 tgtatcaaaa gctatcgttt gtatcaatgt ccaacatgcg ggaaaaaata taccttgtct
      601 tatggcgatt acattttgat tgatgagaaa ggaaagaaac gctgatgaaa acacaacaca
      661 aattattgac tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa
      721 aagtagcaga agctttactt attccgcggt actggacgat agaaacccct ttagtagagg
      781 atgcaccgac tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc
      841 aagaaaacat ggaaacttat gaaatcgaat attggttaac caaattagag aactaaaaag
      901 gagaaaaaat atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat
      961 ggcacaaaaa atggaggata tgacgttcct ataccatgaa acacgtgtac ccaaaaaaca
     1021 ttacaaggaa aaattgtcag tcgcagtgga agaaatgatt gaatcaggtg tcgaaatgaa
     1081 tctcattgcg acgtactatc gaacactgga agaactgaaa aaacaaaatg gaaaatggtt
     1141 tttccaagcc ttactatgct tggaagtagg tgtcaaacca agcactatca aaccttccga
     1201 atatcaagcc ttagaactga cttatgcaaa attcgcacag attaagaaag ctaaagcaat
     1261 ggctagcgac tggctagata cttttgaaag tatcgaaaaa aatggtgcat tttatacgat
     1321 tgaatcggag gagaaagata atgaataagg tggtttatca gctaacaaca gaagatgttt
     1381 cgcaattttt aacaagcaaa gaacacttga atgaagtaat cagacggatt caaaaagact
     1441 ttagttgtat ggaagaaatg aagtacttta ttcaaagagt ggaagaacag ttgtatatgg
     1501 aaagcgaaac aagtcaaacg aaggtcacag tcagccataa tcatttagac gtgtataaac
     1561 gtcgtcctga aacggtaaaa aaaggaacag agcttctacg actagaaaca gaaaaataca
     1621 tcatgaatgt gtacctagaa aggagtgagc tggtcgaaaa ctttgtcagc tacacgattt
     1681 gtaggaaaca ctattactca gaatcagaat attattcaat tttcgagagc atggaattaa
     1741 tggaagaaga aatggaagag ctaaacagca aaaatgcgac ggtagacgat tattaccttg
     1801 tatttactag gtttttgacg tgtgggacgg aatctatcgt gttaatggga atggattatg
     1861 aactcgctgt acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg
     1921 acgactggta cacgacttta actgattttt tagacaccta cacttacgac gatacagaag
     1981 aaatccaaaa tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaag
     2041 gtaaataacc atttataccg aaaagtgagg atgtgtgaaa taagaacaaa aaaccttgaa
     2101 attaagggaa tggttcttat ttcgcaccaa tcgctccaac cgcccccgcc gcttaggtgg
     2161 tgcgaaataa gcgggcaaag cccgataacc taagagaaag aaggagatcc atatgaataa
     2221 aatcattcct ctattgttcg tactgtttgt tggcgagata cttatgcgtc atgctgcagc
     2281 tgtacattta aacttcgtag tattcttagg aatactggta ttttgtttga tcttttggcg
     2341 atttgtatta gcccttgtga gtctactatt caagatgatt gcagccatat ttttcatagg
     2401 gttatttcga tgaaaggaga gagtactaat gccaattgca ataggaaata aacggttacc
     2461 cgtgacatta gatgaaaaga gacaaaaaga attgcagcaa ctaaagcaga agtacggaaa
     2521 aagtgaatct aagattatgt gtattgcgtt agatctattg atcgcgcaag aaaaagcagg
     2581 atttgatata ccagcactaa aaaagtgacg tcacttttca tttgaagaaa caaaagtgat
     2641 agcacttaat tgttcctact atttagaata ttttctatgt cctttttatt ccattttgta
     2701 tcaataacta tgaaatcttt aaagtatcca gaagagatta tttttagatc aatttttttc
     2761 ttacctgatt ctaaagattt tgttttctta aacatattat gatttccttt cgactatttt
     2821 catataaatg ttaacatagt ttatggattc atggaatgtt aatctaattt aatagaaaag
     2881 gataattaag tatatacgtt ttttcttatg tatgttatac tatgtatata cagaaagagg
     2941 tgtctactat ggaaatgtta cctataaaaa aatggggaaa tagtaatggc cttagattgc
     3001 caaagtatat tatggaatat cttggaattc atacagaaga caaagtgaag ataatacaag
     3061 aagaagtaaa cggtcagaag cggctaatta tcgaagcggc taatatagaa aatgaattaa
     3121 caattgaaca gttatttgaa aattacactg atgaaagaaa tcatgtgacg attcaaaatt
     3181 taggtgaagc agtaggtaat gaaaaatggt gagaaaacct agacaaggcg atattctatt
     3241 attgaataca gcacctcgat ctggacacga acagacaggt aaaagacctt atattgtttt
     3301 aagtcatgat attattgcgg attatagtaa cgttgttaca gttgctccaa tttctagtac
     3361 aactagaaac tatccgctat atgtaaatat aaactcagaa tatgaaatga agacaacagg
     3421 aaaagtatta ttagatcaac taacgacaat tgattatgaa gccagagagt gtattttttt
     3481 ggaaaaagcg catgatagtt tagttgagga gttattgatg aaagttagaa cagtttttca
     3541 aaaagtaagc aaataaaata gaaacagcag catgatcaac tattcgtgat tgaccatgct
     3601 gtcttttttt attctatata cggtttgtct cgtaacattg tagtcttttg caatcttagc
     3661 gatcgcaaca ccttttttta gatcctcaac gatgttttta taaacaagac gacgttgggg
     3721 atcttttgca ttggcactgt atagcttagg acgtccttta taaacaccgt tcgcttttgc
     3781 aatcttaatg ccttgtgcct gacgtcgttt agattcggta cgttcttgtt cagcgatcat
     3841 ggccaaaatt tgaatgatca aatctttaat gaatttatcc aggagaggat tgccaattgc
     3901 ttcggccatg atcggtagac ttgtgatgat cagctgcaca tttttcttct tcaagtaatt
     3961 gactgaagcg atgatctcgt cgtaatttct tccaagtcga tcaatagctt ccacaataaa
     4021 aatatcttga tctcggacga aatccagtgc ttcttgaaaa acaagtcgat gagtaatcgt
     4081 tgcgccagat tgtttctcaa tgaaaattct ctctgcaccg aattttttca tttcttcaat
     4141 ctgccgttgt tcattttgat cgatggatga gacacgtatg tatgcaactc tcaaaatttt
     4201 tacctacttt ctgcaactat ttaaaaaaca ccctaatcat acacgagaaa accagatttt
     4261 tcaatgtcgc ggtcgtgtct agttagggta taccttatat agacaaaaac taatgatgga
     4321 ggaaatagta tgtgtcactt ttctttttaa atggcaatat tttttgtaaa taaatgtcaa
     4381 tcaagaaaat ttaaacgatt atgacattaa aaatatattt tatgaatttt ctagtatata
     4441 acttgattta tctgttaaga tttattaaga aaacgttttc ttatttttga tttcgaggtg
     4501 atagacaatg aaaaataagt ttattttatc tttaggtatt ttaactattg gaattagtgt
     4561 aactggaact acaattccta catttgctga tagtacaaat gaaccaacta ctgtagtaga
     4621 taataaccaa gaattaactc ctttagatag gaacggaata gccattggta acccaactaa
     4681 cgacttaact gttactgaaa attatttaat agtttctcca ttacttgctc gagcagcttc
     4741 taaaacgata cgagtgacag gaacgatgat ttttgataaa gttggttggc cttctagacc
     4801 tcctcaatca cggaattgga aagaaaaaag aaatggttat tggtactatg gaaaattgta
     4861 tttacaaagt tataaatcag ctggaaacaa ttggattgcg acttattcag gaaccttaac
     4921 tagaaagtag ggatttttta tgccagaatt tgtgaacaca ccaaattttt atcaagatag
     4981 cgatattcta agtaaaatta atttaccgaa agaagaatca gctttacaag ttcagcgaac
     5041 tttacaggag acacaaaaaa ttcaaaaatc aatttctaat ctagaagatt ctgaagaaaa
     5101 aagaaaaaaa agagaccaaa aaacatatca aaaagaaaaa taatgatttt aaaaaaagag
     5161 tgtctagtcg acattctttt tttctaattg aaagtgttca taaaatcacc catttctgga
     5221 cactttcttt ttttgcttta tttttcaaaa aaacaattca tttcatgttc ataaacccat
     5281 aacaatatct atgttcagtt aaactatatg gataaagtta tgttacaata aaattaatga
     5341 aggagtgatt tttttgaaaa taggatacgc ccgggtatct actggtttac aaaatttgga
     5401 tttacaagaa gacagcctaa ataaatttgg ttgtgaaaaa atttttactg atcatatgag
     5461 tggggcaaaa agtaatcgac caggattaga aatggccatt gattttgttc gctctggcga
     5521 tacacttgtc gtttggcgct tagatcgttt aggtagaaat atggaagatt tgatttcaat
     5581 cgtcaatcga ctgaatgagc gtggtgtgag ttttcatagt attcaagaaa atattacgat
     5641 ggacaaatca agttctacag gacagctcat gtttcatttg tttgcggcat ttgcagaatt
     5701 tgagcgtaat ttgatcctgg aacgatccgc agcaggacga gcagctgctc gtgcaagagg
     5761 acggtttggt ggtcgtcctg aaaaattgtc tgaacaagat ttggaattac tgaagacttt
     5821 agtggatagc ggtacaccta ttaagactat tgcggaacgg tggaacgtct caagaaccac
     5881 catttatcgt tatttggcaa aaatggagga gaaaaatgga aagacaaatt ctcattagtt
     5941 tttgtcattt aatgctgaaa atttttgcca tttatctaga aaagtgacaa tagtatgaga
     6001 attttttgta agtgtctact gataacttat tctcaaatgt tgtaaggatt ttattcattt
     6061 gttaatat
//
LOCUS       DAZKNV010000107         6068 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000107 DAZKNV010000000
VERSION     DAZKNV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.110"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            832..1566
                     /locus_tag="ACG8M1_002699"
     CDS             832..1566
                     /locus_tag="ACG8M1_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0423353.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="ACG8M1_002700"
     CDS             1582..2751
                     /locus_tag="ACG8M1_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0423354.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="ACG8M1_002701"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="ACG8M1_002701"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFQ0423355.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="ACG8M1_002702"
     CDS             3841..4767
                     /locus_tag="ACG8M1_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFQ0423356.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="ACG8M1_002703"
     CDS             4786..6036
                     /locus_tag="ACG8M1_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0423357.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2027 a          997 c         1246 g         1798 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacaa caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agttaagt
//
LOCUS       DAZKNV010000108         5986 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000108 DAZKNV010000000
VERSION     DAZKNV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.111"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(41..562)
                     /locus_tag="ACG8M1_002704"
     CDS             complement(41..562)
                     /locus_tag="ACG8M1_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFQ0423358.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(564..1598)
                     /gene="sppA"
                     /locus_tag="ACG8M1_002705"
     CDS             complement(564..1598)
                     /gene="sppA"
                     /locus_tag="ACG8M1_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFQ0423359.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(1631..3046)
                     /locus_tag="ACG8M1_002706"
     CDS             complement(1631..3046)
                     /locus_tag="ACG8M1_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFQ0423360.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(3015..5168)
                     /locus_tag="ACG8M1_002707"
     CDS             complement(3015..5168)
                     /locus_tag="ACG8M1_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFQ0423361.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            5426..5662
                     /locus_tag="ACG8M1_002708"
     CDS             5426..5662
                     /locus_tag="ACG8M1_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFQ0423362.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            5681..5896
                     /locus_tag="ACG8M1_002709"
     CDS             5681..5896
                     /locus_tag="ACG8M1_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFQ0423363.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
BASE COUNT         1872 a         1098 c          901 g         2115 t
ORIGIN      
        1 ccactaatta aaatcaaaat aaactctgtt tttctcttat tcatttaatt ctctccagat
       61 taagtgtttt agaattagaa attttttgac catagttaat agcttctaat gaacgaataa
      121 caaccactga cgtgttagaa aaataatccc caatatgttg tttcttgggc gtgaaagcag
      181 ccaccaaata cccaatttga aatacaaaat tttttaatat aaacctacat atacactcac
      241 gaataaagat agtttgccaa cttagctctt tttcctcaaa gctcactact cttatcccaa
      301 aaatcatttt cccaattgtt tgtcctgaat tcagcttagt caaaagtaca aaataggtta
      361 aataaatagc taatgacgct ataccataaa aagtaataat ggatttgtca gattccagtc
      421 ccatgatttt gtaaaagaga cctatagtag catgggtgat gatgctaata caaattaaat
      481 caataagaaa agcaaaaaat cgtaaccaaa atcccgcaaa tacataatta ggcaaagttt
      541 caatgccact cttcttattc attttatagc cctccatagt aatacattgg ttttggagta
      601 tcagaaaatc caagtttttc aaaaactgaa attacacgat ctgatgtagt tgcctttagc
      661 ccttgccatt cagcaatctt attacctaac caagaagaag caaagccagt tgtgtcattt
      721 ttatattcta taaccgtcgc atcagttaat ttcttctctt tttttaggga atctaatgca
      781 tcttcagagt aaccaatttg atccaccaac ccattttcta ctgcttggtt accatcataa
      841 attcttccat ccgcaagttc tttcactgca ttagtatcca tatttcttcc ttttgctaca
      901 acattgacaa aacgatcata agcactcatc acaaattcct gtataacttt attctcttcc
      961 tctgaaggtt tgtgttgagg tgacatcata tcttttaatg caccactttt atacgtcgca
     1021 tcagttacgc caagtttttc taataagcca gaataattta aaccagaaat aatgacacca
     1081 attgatccag ttgttgtttc ttccgtagca aatattttat ctgaaccagc agaaatgtag
     1141 taccctccac ttgccgctgt atttttaaat gcagtataga taggaatatc tagcttttta
     1201 atttttgcca tttctttagc aatctcagca ctttcatata ttcctccccc aggtgaattt
     1261 acttctaata acactccctt aaccgctttg tcttcttgaa ttttctttag ctgtgttaaa
     1321 aaattctgat ggttatattg ttccctacta aaaagattgc tttcacctgt atctgcaata
     1381 actccattga cggatagttt gacaatcttt ttatttgatg cgccttcttc taacgtttct
     1441 tctgtgattt cgttagatcc gtaaaaaatc ttatttattc ctgttagggt tgtatttgat
     1501 gcttcctctt tatcttttcc tggaattagc gcgacgataa tggatagtaa caataatccg
     1561 cacgctactc ccacagcaat ccatcttctt ttattcatat aaactcctcc tatattctta
     1621 gtaaaaataa ttatttttta tttagaaaca catcgacaat ttgttgccaa tatgtttttt
     1681 ctcctacaat taaagacaac tctccagtta atccataacg aaacggaaac gattgagttg
     1741 tttttaacgt tcctttcact gcataaaaaa cacctttctc agtggcagta gaattttctg
     1801 aaatttcatc taaagttccg tcgatcgtaa tcggagcccc acctttttga tccaatttaa
     1861 aatgaacctt catcccttct ttaatatagg tactttcatt cgcaggtaaa agtgctgtaa
     1921 atttcatttt tgatttttcg tggatcggat aaatttctgc aagcactgtt cctttggcta
     1981 gttctgcttg tccctttgtt tcttcattta aatgaaccgt tccagataca ggagctttta
     2041 gtattccttt tgaaagttga tcgtccaaac ttttgataac tgactggttc ttctcttgtt
     2101 tttcatttag ctctgtaact gtttgtttta cagttgttat tgcttgttct agctcttgct
     2161 ttcctttttc cgtttgacta attctgtcat tctcagaagt agttggttta actaatttag
     2221 ctttttctga ctgatactgt tctacttctt tttttagttg ctcaatttgt tcatttatgc
     2281 ttgctgaaat tgtcagtttc acttgatttt tttgatcatc agaaacatta tttagttgtt
     2341 cttgccaatt ctcatagttt gccatcattt cttttgaaaa atcttttaat gattgattat
     2401 tactccaagc tacctgtact tgttgccatt cttgtaattt actatctgaa ctctcaattt
     2461 gtttttctag ttgtcttttt gtcttttcgt atacttctaa ttgcttttga tcatttaatt
     2521 cactttgctt caaagcgtag cggagtgatt ctttttctga caacatgctc tttaattgat
     2581 tactgtagcc aaaactgtca tccgttgaaa acaaattttt tcctttactt atactttcaa
     2641 taaatagctg agccatcttt atttgttgag taatacgttg gttttcttgt tctatctgag
     2701 ccttttcatt ctctattaaa gaacaatcca atctaaccaa cacatcgtcc ttatgaacaa
     2761 attgattttc ttttaggaag ttttccatta ttttagcttc taatggcact tgtaacttct
     2821 ctattttttc ggggttcaat tgagccgttg tccgaataac aacctctttt ttagcaaagg
     2881 ttaaaaacaa tccaataata cataaaaaaa gaattacagg gtataacacc caacggtaga
     2941 agctatgatg ttgtttagta tagatactag aatgttcgaa ccaattatta ttctgcataa
     3001 attgtttccc tctcctagat ttcccataat ttttgataga taccatcggc aaaacgaagt
     3061 tcatcgtgcg ttcctttttc taccaaatgc ccttcatgga gaactaaaat ttgatcacat
     3121 gcttttgcta ttggtaaatg atgcgcaata aaaataatcg ttttttcttt taaattgagg
     3181 agataattca taattgcatg ttctaacaag gtatctaatc cactagttgc ttcatctaaa
     3241 attaatatgt ccggattttt taataaagcc cgtgctaagg ctaatcgttg tcgttgccct
     3301 cctgaaagat tatttccacc ttcttccaac aatgtctcgt aacgtaatgg ctgttgatta
     3361 ataaattcat ttagttggac tatctcacaa acttctatta tttgttcgaa acttggtggg
     3421 ctatctaaac cgaatataag attctcaatg attgttccac taaagaaaaa tgactcttga
     3481 ggcaaatatg tcactcgatc gcgtaatatc tgaaaaggaa tgtctaagtg attaatgttt
     3541 ccataatgga tcgatccttc tgatgcttca taaaaacgaa caaataactt tgcaagagtt
     3601 gattttccag aaccactaac tccaactata gccgttttac tgtgcgaagg aattgtacat
     3661 gaaatttcgt tcaacgttgg ggccttcatg ctatacgaga atgaaacgtt ttttacagtg
     3721 atatcttgtt gaaataattg ttcagaaagc atatattcaa aagactggtt cgatttttct
     3781 gaatcaatcg cgaaaatttc atttaaacga ttatttgcaa cttgagccgt ttgcattttc
     3841 acttgtaaat taataatgtt ttgtaaagga tctgtcaaaa atactagtaa agcattgtat
     3901 gtgataagtt gacctagact aattctatta tccataacaa aataagaacc tagccataaa
     3961 attaatgcac tgctaattaa ttgaatcaaa tgtttaattc cttgttgaat attatcaagc
     4021 gtaaccgtac gaaatgattt tttcattaat ttaacaaatt catggtctat acggttatat
     4081 actttctctt caccgctata tgctttaatt gtttctattc ctttaagact ttctatgata
     4141 ctagaattta cagctgcacc ggctgccatt tcttccctgt tcgatttttc atagcttttc
     4201 acgaaagcga atattgcaac tacataaaaa ggcaaagagc atagagtgat taaaaacaac
     4261 gtactattct gaatagctaa cgtaacccca acaagcaaca ccataccaat atctaaaaat
     4321 attgataacg tagcacttgc taaagcatca ataatcttac tggcatcaag aaaacgagaa
     4381 ataatttccc ctgattttct cgtagcaaaa aaattcattg gtaaagttaa cacatgtttg
     4441 aaatactgaa gcataattgc catactcatt cgctgtccta aaataataag aagataacta
     4501 cgactatatt caaacaatac ccgaaataaa tagacagcga tcaagccaat ggaaattata
     4561 tttaaagttg aacgtgcttg attagggatg aaaaaatcaa gaataccttg aaaataatat
     4621 gagcttccta tgccaaaaaa cgtaatgaaa atcgatgcta aaacgatgtg gaatactaat
     4681 cctttttgtt tccaaattat aggcaaaaaa gaacttaatc cagctacttt ttctttaata
     4741 ggaatataag tttctctagg cataggtaat aaaagaatac ctgtccattc tttttgaaac
     4801 gcttcaatcg tttttctatt ttttccatta gcgggatctg caatccatag tacgtttccc
     4861 ttcgttttat aaattacaac gtagtgcata tagctgttat caaccaatat atgtgcaatt
     4921 aatggtaaga taagatctct ttctttccag atctcactat ctgcttgaat agccatacaa
     4981 tcaaaagaca atttttcaaa tgtctttttc aatccaaatg ctgaagtacc ctctaaatca
     5041 gtcccagata ggtcccgtaa tttatgaatc gggatatcag ttttaaaata ttttaaaatc
     5101 atcgaaaggc aagcaacacc acaatctttt tcatcttgtt gctgcacaaa aggaaatgat
     5161 tttatcactt atctaacaca actccttcta aaaaattttt atagaaaaat tctcaatata
     5221 gctttaatac agtgaaaata ttgtctcata attccacaaa aactttgaaa acagttcttg
     5281 aacactaact ttttcattcc tgaatcaaat ttattttgga aattttacta ttcaagaata
     5341 aacttgataa gtttcaggaa gatttttact gttaatcaaa tacgtatgtt acagtagcac
     5401 cgtaaaaaat attatttaaa gaagcgtgtt taaacatgca aaatgtaaag gaactaagta
     5461 ttgtggaaat gcacaaactg ttggtggagg caataatgct tggggaaaat tggggcaagt
     5521 tgtaggtgga cttaccacag gggcagtagg tggtgcaggt ttaggaacag caatttgcgg
     5581 accagcttgc ggtgttgttg gagggttata tggagctgtc gctggaggtg ctgcagctgg
     5641 ctgggatgct cgaaaaaaat aaaaaaggag aataagtagt atgcatatta aaaacacaaa
     5701 aacaacattt atattatctt cagaagagtt gaaaaatatt caaggtggga gtgccgtggg
     5761 agttttaggc actacttttt ctggggcaac agcaggagta aaactttgtt cagccggagg
     5821 accttatgca atagctgctt gtggtgtagg tggagcttta ttaggtgctg gattcagcat
     5881 gtggaccggt gcgtaaacaa ttaaaaaata tcaaacctca agattggttt gtgtcgatta
     5941 cgaacatagg tatgttcttt atcttttcaa aagtttggaa tggaca
//
LOCUS       DAZKNV010000109         5953 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000109 DAZKNV010000000
VERSION     DAZKNV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.112"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(24..986)
                     /locus_tag="ACG8M1_002710"
     CDS             complement(24..986)
                     /locus_tag="ACG8M1_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0423364.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(988..2427)
                     /locus_tag="ACG8M1_002711"
     CDS             complement(988..2427)
                     /locus_tag="ACG8M1_002711"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFQ0423365.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2612..4558
                     /locus_tag="ACG8M1_002712"
     CDS             2612..4558
                     /locus_tag="ACG8M1_002712"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFQ0423366.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4822..5694
                     /gene="scrK"
                     /locus_tag="ACG8M1_002713"
     CDS             4822..5694
                     /gene="scrK"
                     /locus_tag="ACG8M1_002713"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFQ0423367.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1882 a         1024 c         1057 g         1990 t
ORIGIN      
        1 gacattaaaa aattaattta acgttaaata cttcctccag aaagtattga gattggtaaa
       61 atataatcct tatttgtctt ttcgccttta atttttttca gaagaatatc aacaataaga
      121 cttgcaattt catcaattgg ttgtcttatt gttgtcaatt gtgggaaaaa tttctcaata
      181 aaagaggtac catcgtatcc aataattttt aaatcttctg ggatattaag tttaagttga
      241 tgagcaattt tcatagtgag aatggctgtt aaatcatcag aaacaaaaat accatctggt
      301 ttgtgattta taatagttga ctttatttcc atttcacgac ggatagtaga cagattatta
      361 ggaattttga aaatttttcc atttggattt tgaaaagaaa aacctagtgc acgtaattct
      421 gtgggagaat ccgtgttatc atttcctgta atcataatgg tattttgaca accatttttt
      481 tgtaaagtct tagctgcaag ttttccccct tcaaagttat ctgaagaaac aatggaaaca
      541 ttaggagcta aatttctatc aaaagcaaca ataggtgctc tcacacgctc ataatcagca
      601 attccaagat tatggcttga tgagattatg ccatcaactt ggttggcttc aagcatttca
      661 atgtattctc tctctttagc aggatcattt tgactattgc aaataatcgt tttatatcca
      721 tgtttaaata actctatttc gagatactca atgagttcag agtaaaagat attactaata
      781 ttaggaaaaa taagaccaat aagctgaggt gactttcctt gaagtccacg tgctaaatta
      841 tttggtttat aaccaagagt tttcatagct tcatgaactt tttgttttgt tttttctgat
      901 aaatatccct tattattaat gacgcgtgaa acggttgttg ggctaactcc agctaattca
      961 gcgacatcag ttaattttgc taccatttta atattttaat tcaaagtatt ttccagtagg
     1021 ttcgcctgat ttgatttgaa taccattttg gtgattttca gggaatacac gactagtaaa
     1081 cactttttct cctttattaa taaaaatctc aatgattgag ttatctacaa aaatgttagc
     1141 agttgtttct ttagtatcaa ttgagcattc acgaatcgta ccaaagtcag tggcatattg
     1201 aatgcctgct ttgctgcgat ctaaaataat ttttccttct ttggtatcta caatcaagct
     1261 aagtccattt cctttactat cagagaaaag aagtaactcc gatttctgat ttggaggaaa
     1321 agttagttca agctcataag tattatttgt ttctgctttt gctgtaaatt gttcagaact
     1381 agcacgtaat gatgtaatag cttctactgg atattggtaa agtttaccat cttttattga
     1441 aagttctttt acaagactca ttgctccctg ataatcatac ttatcagttg gataatcgat
     1501 atcaggtagt ccaatccaac tgacaatcag agcacgacca tcaggagtat tgaatccttg
     1561 agtcgcatac gcttcaaatc cataatcaag attttgaatt tctgaagcgc ccacaagttt
     1621 tactttttct atgtcaagcg attgacagat cttaaaagta ttcggataga tattcccata
     1681 atttagctca gatttatcca acccttgagg acaataaatg agaacaggtt ttttgtctac
     1741 aaatactaga tttggacact caatcatgta ttctgaacca gtgccgccaa aatcaaggtt
     1801 gccaacttcc tcccatgttt ccacgttatt gtcatccgct ttgtaaagtt tgataaagcc
     1861 tgatttttct aaattttgtg ctccaacaat cgcatacaat tgtccttcat aattaaacat
     1921 ttgtggatca cgaaaatgat cagttacatc agcaggttta tgaataagaa cattctcacc
     1981 tttcgtaatg ttgtagtctt tatccatcca tgctccgatt tgaagtgtat cacgttccca
     2041 attttcattt cgaacgtttc ctgtatagag taagaataga ttcccctcta tttcatatgc
     2101 agaaccggaa taagcgccgt ggctatctcg ttttgtgtct ggaagaagtt ctgctcctgt
     2161 tacatgaaaa tgaactaaat catctgattc attgtgtacc cattctttca acccatgagc
     2221 agctccaaat ggccaatttt gataaaaaag cgtatatttt ccgttaaaaa aagaaaaacc
     2281 attaggatcg tttaacaatc ctgttttagg ttcgatatga tagctagcac gccaaggtga
     2341 tcgttttaca ttatccttaa ttttatccat ctcatcttta gtccaatcag aataagcacg
     2401 atatcgtatt tctcgaggta agttcatatt ttactccttc aatttatctt tttacaacta
     2461 gtatggtaaa cgttttccgt tgaaaaatca atcatttcat ttaaaaaaat aaactatatg
     2521 acaaacgttt gacatatttt taagatatgc taaaataaat ttgcatttca gtgaaccgtt
     2581 ttcacgtaaa aataaaaaag gagtgattcg aatgaattac agtaaagtag cttccgacgt
     2641 aatacaagcg gtcggaaaag ataaccttat tgcagctgca cactgcgcta cacgtcttcg
     2701 tctcgtacta aaagatgaca cgaaagtgaa tcaaaaagct ttagacgaaa atccagatgt
     2761 gaaaagcaca tttaaaattg atggacaata tcaagtgatt atcggtgcag gtgatgttaa
     2821 tttcgtttat gacgaactta tcaaaaaaac tggactttcg gaaatttcaa cagatgattt
     2881 aaaacaaatt gctagtaaag ataaaaaatt caaccccatt atggcattaa ttaaattatt
     2941 atcagatatt tttgttccaa ttatacctgc ccttgttgca ggtggtttat taatggcatt
     3001 acaaaacttt ttaacagctg ctggactttt tggaccaaaa tcaattgaag aaatgtatcc
     3061 tgcgattgaa ggtatttcct caatgatcca actgatgtcc gctgcaccat tcatgttctt
     3121 accaatttta gtaggtattt cagctgctaa acgttttgga gcaaaccaat ttcttggtgc
     3181 tgcaattggt atgatcatga caacaccaga tcttggtggc tcaactgaat attggaatat
     3241 ttttggttat catgtttcac aaacaaacta tgcttatcaa gttattccag ttttagcagc
     3301 tgtttggata ttatctatat tagaaaaatt ctttcataaa aaattgccat catctattga
     3361 ctttacattc acgccattat tatcagtaat gattactgga tttttgactt tcacagttat
     3421 tggccctgta atgttattgt tgtctaatgg aattacagac attattgttt ggctatataa
     3481 cactactgga tttattggaa tgggtatttt tggaggaaca tattcactta tagtcatgac
     3541 tggtttacat caatcatttc cagctattga aactcaatta ctttcagcgt ggacaaatgg
     3601 tatcggacat ggagacttta tctttgtagt tgcatctatg gcaaacgttg ctcaaggtgc
     3661 tgcaacattt gccatttggt tcttaactaa aaattctaag acaaaaagtc ttgcttcctc
     3721 tgcgggtgtc tcagcacttc ttggaattac agagcctgcc ttgttcggag ttaacttaaa
     3781 ataccgcttt ccattctttt gtgctttaat tggttcagga attgctacag cagtagcagg
     3841 attacttaaa gtagttgctg tttcacttgg ttcagcaggt ttcttgggat ttctttcaat
     3901 taatgcaaca tctattccat tttacgtatt gtgtgaattg attagctttg tagttgcttt
     3961 tgcaattact tacttctacg gtaaaacaaa agctgctggt atctttaaag cagaagaaat
     4021 tgctgaacaa acaccagtta attcttcaaa agtagcaaca acagatccaa tatctactga
     4081 tgttgaatca acacaaacaa aagtttcatc agaaacaatt gttagtccca tttctggtaa
     4141 agtgattagt ctttcttcag taaatgatcc agtcttttca tcagaagcta tgggaaaagg
     4201 gattgccatt aaaccaaatg gaaacacggt ccattctcca gtagatggta ctattcaact
     4261 cacgtttgaa actggacatg cttatggtat taaatcaaat aatggtgctg aagttctaat
     4321 tcatattggt attgatactg tatcaatggg aggaaaagga tttacacaaa aagttactac
     4381 taatcaaaaa gttagaaaag gcgatattct tggagcattt gaccgttcaa tgattgagaa
     4441 agaaggtctt gatgatacaa caatgattat tgtgaccaat acttcggatt attcagaagt
     4501 aaatatagta gctgaaaata cagtcactga gggtactgat ttacttgaaa tcaaataaat
     4561 atatttccct gagtaaagat ggaattttct ttccaaaatc aaataatata gattaatcaa
     4621 atatttgaga ataacatttt atttaatctt ttcatatatc aattgtatga aaaattatta
     4681 gaattttaaa aaatgataaa aattcaaaaa gaaaaaatag tagttattta cttgtcatgt
     4741 tactaaataa aaaaataatt taaatatgat atatagtcat ttatttagtg atttcattct
     4801 aaaataaagg gagaaatgtc tatgctatac ggtgcaattg aagcaggcgg cacaaaattt
     4861 gtgtgtgcca ttggcgatga agaaatgacg atcaaggaaa gagtgagctt tccgacaacg
     4921 acacctgagg aaacaatgcc tttagtcatt gacttcttca aacaatacca agcagattta
     4981 gcagggattg ggattggctc atttgggcct atcgatatcc atcgcgattc cgccacttat
     5041 gggtacatta cctcgacccc gaaattggca tggcaaaatt ttgatttcat cggtaccatg
     5101 aaaaaagaat ttccgatccc gatttcttgg acaacagatg tcaatgcggc tgcctatggt
     5161 gagtatgtct tcggcagtgg caaaggattg agcagtgtcg tttactatac gatcggtacg
     5221 ggtgttggcg gcggtgcctt acaagaaggg cgctttatcg aagggtttag tcatccagaa
     5281 atggggcata tgctcgtcgt ccctcatcca aaagatgact ttgctggcag ctgtccattt
     5341 catggcaact gtttagaagg gatggccgct ggacccgcca tcgaaaaccg cttagggaaa
     5401 aaaggacaag aggttgcaga agatgatcct tattgggaaa tcgaagcctc ctatattgct
     5461 caatgtgcct acaatacaac cttgatgttt tctccagatg tgatcatttt tggcggtggt
     5521 gtgatgaaac aacgccatat gctgcaaaac gtccacgacg catttgcaaa attggtcaat
     5581 gggtatgtcg aaacacctga gttaagcaaa tatatcgtga ccccagcatt agaagacaac
     5641 gctggaacgc tcggttgttt ggcattggct cgagaagcgg tcttacattc ataaacgaaa
     5701 aaaggctctt cgacatttag tgttggtaga gaaagataca actgaaaatt tagtcataac
     5761 cagttaggca gagtgcttaa ctggtttttg ttttacttgg aagatcaagc cttgaatgag
     5821 ataaattctt gctcgaaagt tatggaaatt tcgatagccg taggccactt gtattgtgca
     5881 atagtttttt acaaaaaaaa gggggtgcgg atattttttt ggaccttttt aacaaatata
     5941 tctttgcttc ttc
//
LOCUS       DAZKNV010000110         5809 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000110 DAZKNV010000000
VERSION     DAZKNV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.113"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..700
                     /locus_tag="ACG8M1_002714"
     CDS             <1..700
                     /locus_tag="ACG8M1_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423368.1"
                     /translation="YSLFKTLQQNRVAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIF
                     SYLLVQFIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQF
                     INGYMYLFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIH
                     TDIVHTSIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSN
                     IQQNKPYVLGKVVI"
     gene            744..1013
                     /locus_tag="ACG8M1_002715"
     CDS             744..1013
                     /locus_tag="ACG8M1_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423369.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1245..1541
                     /locus_tag="ACG8M1_002716"
     CDS             1245..1541
                     /locus_tag="ACG8M1_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423370.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1543..1965
                     /locus_tag="ACG8M1_002717"
     CDS             1543..1965
                     /locus_tag="ACG8M1_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423371.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1984..3576
                     /gene="mobP2"
                     /locus_tag="ACG8M1_002718"
     CDS             1984..3576
                     /gene="mobP2"
                     /locus_tag="ACG8M1_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFQ0423372.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            3597..3917
                     /locus_tag="ACG8M1_002719"
                     /pseudo
     CDS             3597..3917
                     /locus_tag="ACG8M1_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4078..5219)
                     /locus_tag="ACG8M1_002720"
     CDS             complement(join(4078..4991,4991..5219))
                     /locus_tag="ACG8M1_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0423373.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            5467..5661
                     /locus_tag="ACG8M1_002721"
     CDS             5467..5661
                     /locus_tag="ACG8M1_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423374.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT         2043 a          918 c         1162 g         1686 t
ORIGIN      
        1 ttattcttta tttaaaactt tgcaacagaa ccgggtggcc tattacttgt taagtgagcc
       61 aaaacagatc gcggcgtcaa atattttcac ggcagtaatg acattaatgt gtgtcatgtg
      121 cttttctatt tttagttact tactcgtcca atttatcagg caaaatttaa caatgagtaa
      181 acttttcaaa agtttattgg acttacttat cttaggcagt atgttaacga ctctaacaga
      241 tcggttcgaa caatctgaaa aaacggtaga ggggataaag aacttcttaa cgacgattga
      301 tcaatttata aatggatata tgtatttgtt tgaagtaggc tttattctca ctttgtttgg
      361 ttgtgtattt ataaaactca ttaaaagatc aatcgaaaaa gaaatggtta ttgatctaat
      421 tccgacgctg agcggctatg agtattacgt tgattttgga aagtatgagg agttgatcca
      481 tacggatatc gttcacacga gtatccatga agtaaccgtt aagggcatca gatctacttt
      541 aaaagatgga caggagacga aaacaatcga ccgaagaaaa gaggtctaca atttttataa
      601 agttgaagca agtctacgat atggcattgg gaaattgagg ttagatggga gtaatattca
      661 acaaaacaaa ccatatgttt taggaaaagt ggtgatttag aacttcctat gaaagatgaa
      721 taaataagga gaatcttttg aaaatgattc ttctttacag aattgtgctt atagttggca
      781 cggagttaaa aatcttaaag aaggagcagt tattcaaagt gaaagaacat cataatcagt
      841 tactatgtat taaaacgggt acgatgaaca ttcaataccg aacagaatat ttagaattaa
      901 cgaatcaaac tgattttttg tcgattcgag agcaacataa gcaagaaaaa ttaatggcta
      961 cttatagcca attgattgat gagtgggaac aattcaagga atctaaaaca taaaattcca
     1021 tttaaacacc ttatttttta aagagcataa ggaaacgtga ccccactttt aaaaaaagtg
     1081 gttggatagg ctgtgcctat cacgtttctg aaaaaaataa atgaccccaa aataccaata
     1141 tataggatag tacaaggata gcaaaggata gtaaaaggat agaggtagga tagcgaaaag
     1201 gataggatcc ttttcactat cctatattat attggaggat atttatgaat gttaaaatta
     1261 gagatttaga tccaaaattc atttctgaaa ttgatcgaag atgcgttgaa ctaagtaatc
     1321 gtacaggaaa taaatggagt cgtaatgatt atttaaagct actcgttgaa aatgattttg
     1381 atcgtccttt gatggaatac aaacaagaaa agtttgacca gttattagaa aagttttcag
     1441 aaattcaaag ttataacaca aagatattag aagaatatgt tagccaaaat aatcgtatta
     1501 tagaaatctt gattgagcaa aatagaggaa gtgaactttg atatggcaaa ggttatagac
     1561 aaacacattt actttcacca aacacatatc gatgtattgg atgaaactat ttctactcat
     1621 gcagaggtta aaaactatag tgaagctgtt cgctttttat gtatgaacta tgatccagaa
     1681 gtggagaaaa aagtaaattc caatcaagca aagttgaatg gaatgagtaa agaaatttct
     1741 attttaaccg aaatggtttc agaatttgcg gatcttcatt tgaaagatac aggaatatta
     1801 attggtaaaa attcaactgt ttatcaagaa gcaaaagaac gagtggaagg aaaaattaaa
     1861 tccaatcaaa caaaaaaata ttcccctcag ttgaagaaac ctgtgaatga atctgttcat
     1921 gccagagtag atccatttga tccaacgaag attctaaaaa gataaaaatg aaggaggata
     1981 ataatgactc aatcgccttc agttattctc acttgtcaat ttactttgcc gaataaaaag
     2041 tcattttcta cttatattga ctatattaca agggaacagg ctcttgaaga aaaggaacga
     2101 cgtacgcccg aagaagaaca ggaacttcaa cgaatcaaga atgctttaga ggagttttat
     2161 attcctgaag gagaaacttt ttcggagagt aagacgggta aagaattcag tgaaacgtcg
     2221 aatgaagctc aatcgttgat ggaacatgga atcaattttg acaagttaga ggaacaagat
     2281 tttaccaatt atctttctta tatgacacgt cactatgcgt tagaacaaaa gaaagaactg
     2341 acgcaaagtg aacaaaaaga ataccaacgc ttgaaccaag caatgaaaaa atatcaaaca
     2401 gaaccccata aaaaagcttc aggaaatctt cctggagttt tttctatagc ttcagacgaa
     2461 gtgaaaggaa gtgatctgaa ggagattaag caaatcttcc aaagaggaca acaaaaaggc
     2521 tcaatcattt atcaagatgt tgtttctcat gataattcgt atcttgaaaa aataggattg
     2581 tacgatccca aaacagatac tttagatgaa gaagggttaa aagcagctgg aagaaaaatg
     2641 atggagacat tattcgagaa agaacaattg aatgaaacag gttactggat ggcaacgatt
     2701 caccgtaaca ctaaacatat ccatattcat tttgcagttg ttgaaaaaga aaatacgcgt
     2761 aaaccttaca cggaggttga aaatggtgtg agttatatcg taccgaaagg taagagaaga
     2821 caagcaacat tagacgcaat gaagaccaat tatgtacatg agttagaacg tttttcttat
     2881 gaaaaggatc gaatgattgg tatggagaaa cgaaatttat tgacgcggaa aagtgatttg
     2941 cgtaacacct taacaaaagt ggtaaaagag ccagcgcgtt acgatcgaca cgcgatgaac
     3001 ttattaaatg aagtatataa aaccctacct gacaaacgtt cggaatggaa ttacggggat
     3061 gaaaaacgaa ccaaactttc accatacaca agagagaaac tcgatgagtt aaccaaatat
     3121 gttttaacaa aagaacctga atatcaagaa tatatacaga tttcaaaagc attgaaagaa
     3181 gaagcaaaaa gtctttatgg ggaaagcaag agagaatcaa aggatgcaga gaaaaatgct
     3241 ctctttgatt taaaaaagcg cacaggaaat gccatcctaa cagagctgaa gagacaggat
     3301 agtcaaataa aaccattaat agaaagtgtt gatcagatgc aatctattta caatgaacga
     3361 tcctttcgaa cgcttaaaca attgccaacg aatgaataca aatatagtta cgaagaattc
     3421 atgaagcgca ggaaacaatt ccaacaaaga gttgtcacgc agcggagttt gcgtcaatta
     3481 aatcgaacga ttaatgccca tgaagaaaaa taccacgcaa gtaaagcata cgaagagcaa
     3541 caacgaagaa ttcaaatgga acaagaaaga cagtaaagac agtaggagga atagcaatga
     3601 aacaatattt agatcaatgg aaagttatag aaggatcatt aagagaagaa cgaatcgaac
     3661 aacttcctga ttgtttagaa aaagagcatt tgttccagat aagagaaatg ttgagaaacg
     3721 aacagtttga tccaaatcaa tttttagtcg ttgagtaccc agctactggt gtgtattgtt
     3781 gtaatcatgt gaatggtgaa aaatatttta tcattcaaga atatgagggc aagttagcac
     3841 cttattatac tacttgggaa atgaatgaag agggaatcaa taactttcca tgtaaaagca
     3901 ttggatttga gtcaatacct cggacacgat ttgtgagaat tttttcgaga ttccagcggg
     3961 tgagtatctc atcgtttcga ccagcggtca aaccaaaacc gtttgaccgc tgatcgaagc
     4021 gatgaagttg aaaccctgtg gaaatctcgc caaaaaaatg taagtggtag ctaggaacta
     4081 agcttgcaat gccaactcct ccatctgatt tggtgttaaa tagttgatac tactatggat
     4141 tcgcttgcga ttgtaaaatc cttcaatgta ttgaaataac gctaaataag cagcttcaaa
     4201 gttttcatac gcttttgatg gatagacttc ttcttttttg agtgaggcgt gaaacgattc
     4261 gataccggca ttatcgtagg gacagccctt acgactgaag gagtgccgaa tgttcaattc
     4321 attcagcttt gcctcatagg cttcgctagt gtactgagaa cccaaatctg agtggatgat
     4381 caagttctcg gagggtgttt ggtttaagag cgcattgtca agggtttcga taaccaattc
     4441 tttcgtcatc tgcttgccaa acttccaacc gatgactttc tttgtgtgga ggtcttgaat
     4501 agtggagagg taggtccagc catcttttag ggtatgaata taggtaatat ctgtcaccca
     4561 tttttgattg atcgacgtag tggtaaaatc ttggtttaac aggtttttac gtccttcact
     4621 tttaactttc gcttgtttgc caggcttgta cttcttgagg gtgactgaac gcaagcctaa
     4681 ttttctcatc agtatttgta ctttctttaa ggacaaggtc tcgccacggc caacaagaat
     4741 cttatgaatt ttaggcgcac catagatacc cttgttttca aagtagattc ctgaaatcaa
     4801 gcggtttaag cgtttgtttt ctgattggcg cttggaaggt ttctttttct tccagtcata
     4861 gtagctggat ttcggtgctt ccaaaacggt acacatttgt tttacgtcat gatcatgaac
     4921 atttgattga ataaattcga agacatcact catttttact tttgagcgaa tatggttaaa
     4981 gcctttttta ggatagtgtt ttcctcctgc atgcgggcca tttccttttt catcgctagg
     5041 atttctgcct cagtcatgcc ggttgctaca ttctttgtat gaagcttctt ccaacgataa
     5101 atcgtttgtg tagcgatacc atattgcgct gccagttctt cgaccgattg gccagactgg
     5161 tttaaatcta agatcatctt cttaaagtct tcatcaaatt ttttcttggc ttttgccatc
     5221 gtggacacgt ccttttctta gtagttagat tctaccaaat cgtgtccatg aaatcatcct
     5281 aacatcacat tgaagagtcc atttcactca cagagtgtta gttgttaagt gaataaaaga
     5341 agtaaaagag tcctgaacgt gattgtccag gactcttttt ttcaatgaat tgttttccgc
     5401 caactcattg agtggtgcga tttgcgacta cattatatca aaagaaagag aagggaggaa
     5461 gcagaaatgg ttcattcaac gattggagtt gttgttgaaa aaagcagaga caatctcgtt
     5521 tttgtgacag aaattcaaac aggcagatct tttgtcgtca cagacaaagc ggcaaaagct
     5581 tatcaaagta gcgatatttt aacgttaaat ctgactacga agacgttcgt cgatgcgaca
     5641 gaagattatc catttgttta gtctaatggt gataagtcaa gatgaaattt aagattttct
     5701 ttattgagta atatgttttg aagcgcacga aactagaccc gatcaaaatc aaattttttt
     5761 cgggttgatt caaggatttg cgtcaataac ggattgttat ttctctatc
//
LOCUS       DAZKNV010000111         5719 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000111 DAZKNV010000000
VERSION     DAZKNV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.114"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            196..921
                     /locus_tag="ACG8M1_002722"
     CDS             196..921
                     /locus_tag="ACG8M1_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423375.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="ACG8M1_002723"
     CDS             911..1420
                     /locus_tag="ACG8M1_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423376.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="ACG8M1_002724"
     CDS             complement(1490..2938)
                     /locus_tag="ACG8M1_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0423377.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="ACG8M1_002725"
     CDS             complement(2938..3654)
                     /locus_tag="ACG8M1_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFQ0423378.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="ACG8M1_002726"
     CDS             complement(3635..3985)
                     /locus_tag="ACG8M1_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFQ0423379.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="ACG8M1_002727"
     CDS             4129..4902
                     /locus_tag="ACG8M1_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0423380.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="ACG8M1_002728"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="ACG8M1_002728"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(5485..>5719)
                     /locus_tag="ACG8M1_002729"
     CDS             complement(5485..>5719)
                     /locus_tag="ACG8M1_002729"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423381.1"
                     /translation="LFEGTCLNHNCVFPSISIKVHLKKSVRTKVLFVNLKIDFPEYVL
                     GISKCLNVFLNAKSMQKILYFSTFLSLTKIKKR"
BASE COUNT         1661 a         1124 c          994 g         1940 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataag
//
LOCUS       DAZKNV010000112         5670 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000112 DAZKNV010000000
VERSION     DAZKNV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.115"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            238..1629
                     /locus_tag="ACG8M1_002730"
     CDS             238..1629
                     /locus_tag="ACG8M1_002730"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0423382.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAEIDFSQEKIYR"
     gene            1688..2491
                     /locus_tag="ACG8M1_002731"
     CDS             1688..2491
                     /locus_tag="ACG8M1_002731"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0423383.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            2524..3378
                     /locus_tag="ACG8M1_002732"
     CDS             2524..3378
                     /locus_tag="ACG8M1_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HFQ0423384.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            3375..4076
                     /locus_tag="ACG8M1_002733"
     CDS             3375..4076
                     /locus_tag="ACG8M1_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFQ0423385.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            4084..5151
                     /locus_tag="ACG8M1_002734"
     CDS             4084..5151
                     /locus_tag="ACG8M1_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFQ0423386.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            5144..>5670
                     /locus_tag="ACG8M1_002735"
     CDS             5144..>5670
                     /locus_tag="ACG8M1_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0423387.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDG"
BASE COUNT         2001 a          840 c         1102 g         1727 t
ORIGIN      
        1 tatatgaata ttgtaacttg tgaataagga attagcagga gaatactagt tcagcataaa
       61 ggaagtgatg ggacttctga gacaactttc tgttatgcag aaatacacat ataaacagac
      121 aataaacgct tttccccgtt tcttttaatt tcctttacaa tttggttatt cactaggttt
      181 ttaaactttg ctatggtaag atgatagagg cattatttta tggttaggag tgtatatatg
      241 aataaaaatg gggagtggaa tgcggcacgc agaatattca ttattcttat ggatgtactt
      301 gtattaaatg tatcgatcta tcttagtttt ttgctgaaat tccagggaga agtaccagtg
      361 agaaacttag aaacctttca gcattcagca atttttattt ccatcatctt tattgcgttg
      421 aatattttgt taggagctta tgtattctat aaccgaatga tcagtgatat tgtcttcatt
      481 actgttattg gacaagtact aatagcattg gggatcatgg tagttacttt tgctggccga
      541 tggtttgcat ttccgcgtgg cgtcattttg atctcgttta tcctaggtac gatattactt
      601 agtgtttacc ggatagtcgt ttacaaactg tacttaagag tcagtcgtga taagaaagtc
      661 cttatcgtgg gtttggagaa agatgtcgca ccagctatcc aaaattttca atctaagaaa
      721 aacaataaac ataaggttga agcagtggca atcgataatt attacgaaaa tacaaaaaaa
      781 ttgatcgatg atatggatat cgtctatttg gcttctaaaa tcccagaaga tgaaaaaatc
      841 aacatttatc aattagtgac taaaaaagag aagaaattat ttttaaatac gacttttgag
      901 aatctgacaa tgataaatcc gaatattatg aattttgaag atgaaagcat cattgaagct
      961 tctgggttca gaatccaacc agaatacgaa ctattcaagc gtctctttga tatcatcgtt
     1021 tcgcttattt tactgatcct cgcctcacct tttatgctaa tcacagcgat tttggtaaaa
     1081 acaacttcac ctggaccaat catctataaa caagtacgta ttacgaaaaa tcaaaaggaa
     1141 ttttcaatct ataaattccg ttccatgagt gcgacagctg aagcaaaatc aggaccagtc
     1201 ttggctaaaa gtaacgatgc acgtgtgaca ccagtaggta aatttatccg tgctgtacgt
     1261 tttgacgaat tacctcaaat ctttaatgta ttgaaaggcg atatgtcgat tgtcggtcca
     1321 aggccagaaa gaccattttt cgttgatcag ttcaatgaag aaaatcctta ttattactta
     1381 agacacaatg tacgtgcggg aattaccgga tatgcacaag tatacggaaa atatgtatca
     1441 gattataaca gtaaactacg ttttgatttg ttgtatatca aaaaatattc attactatta
     1501 gatttgaaga ttttacttca aacaatcaaa atcttatttg ataagatgtc atctcaagga
     1561 ctagatgaag atgaaaatat tagttcatta gcagaaatcg acttttcaca agagaaaatt
     1621 tatcgctaga ttggaaaaat tttgagcaaa gaggtaggag agaacattgg aaaataaaaa
     1681 tgtaagtatg ctgctttctt tatatgataa agaaaagcca gagtatttaa aggaagcatt
     1741 aactagtatt tttgagcaaa cagtaatgcc aaaagaaatt gtattagttt atgacggccc
     1801 tataaatgaa aaacttcaag tagttgtcac ttatttccaa caaaaagatc ctcacttgtt
     1861 tacagttgta aaattagaaa aaaatcaagg attggggatt gctttagcaa ttggattaga
     1921 acatacgaaa aatcgcttag tagccagaat ggatacagat gatataatgg aaccccaacg
     1981 attagaaaaa caattagaga tcttccaaaa agatccagaa atagcgattg ttgggagtaa
     2041 tattgaggaa tttactggca cgcttagcaa tgttatcgga aaaagaattg tacctgaata
     2101 taacaatgca attcgtgtat tttctaaaag aagaaatccc tttaatcata tgaccgttat
     2161 gtttgataaa aaagctattt tggaagtggg aaattaccaa ccattaagtg ggtttgaaga
     2221 ttattatctt tgggcaagat tattaaaggc aggttataaa ggatataata ttcaagaaac
     2281 attagtctat gcgcgaactg gcaaagatat gtatgcaaga agaggcggaa tgaaatatct
     2341 tggttctggt cttatgggtc gttatcgtat ctggaaagac ggtttagggt cagtaaaaga
     2401 ttttataatt gtttcttgcg gacatatttt tattagctta ctaccaaatc aattaagagg
     2461 aaaattttat caaacgcaat taagaaaata ggaggttttt ctttgtatag cactgatcca
     2521 aaaatgaaaa aaatacaaca gattacgttg aaaatgtctc aagagattgt tgatttttgt
     2581 ctaaaaaatc aacttctttg ttatttctgc ggtggtggtg ccatcggtac tgtgagagaa
     2641 caagggttta ttccatggga tgatgattta gatttcttta tgcctagaga ggattatgaa
     2701 aaattttatc aactatgggt taattcagaa aaaagtaaaa aatatcccat acagaaggct
     2761 tctaaaaatt ataatgatca taattctttt acaactatcc gcgatgcaga tactacattt
     2821 attaaaactt atcaaagaga tttagatata gtccatggaa ttactattga tattttcccg
     2881 ttagatgttg cccctgtttc gaaatttagc cgtaaaattc aaaaactatg ggctttagta
     2941 tatgctttat tttgttctca agtcgtccct gaaaaacatg gtggaataat ggctacaggt
     3001 agtaagatac tcttatctat tttccgctca cctcgtacga gatataagat atggtctttt
     3061 gctgaaaaac aaatgacaaa atataataat gaaccaacgg gctatgtgac tgaactttgt
     3121 gtcggaccta aatacatggg aaatgtttat cctgcaaaag actttgaatc tgctgtgtgg
     3181 gtgccattcg aagatacaga gatgccagta ccagttggtt atgataatta tttaagtcaa
     3241 gtttttggtg actatatgca gcttccacct gaaaaagatc aggtttctca tcatgaagca
     3301 gtttatattg atccagaaca tccatacaca atgtacaaag gaaaatatta tttaactaaa
     3361 ggagcagaaa aaaaatgatt acagctatta ttattgctgg tggtgtgggt aaacgaatgg
     3421 gacaagatat cccaaaacag ttcattacaa ttgaaggaaa acctattatt atctatactt
     3481 tagaatcatt tcaacaccat cctcaagttg accggatttt agtcgtttgc aaatctggtt
     3541 gggaagaaac gatgtgggcg tatatcaaag aattcaatat tagcaaagtc aaatgggtca
     3601 ttacaggtgg atcaaaggga caagagtcga tcaataatgg tgttcagttt ttgaaagact
     3661 attctgaaga tgatgatacg atcatcatcc atgatggaat ccgtccacta gtagacgaac
     3721 tggtattgtc agatgtaatc gttaaatgta aagaatttgg taacggtgta acctctctac
     3781 cttacaacga acaaattttt atcaagaaaa cagaagaaac gacggaacag tatgtcgatc
     3841 gtaacacatt gaggcgtgtc tcaactccac aagcttatca atacggaaaa ctacgggcag
     3901 catatgaccg ggcagtgaaa gaagacatcg gtatgactga ttcttcttat acgaatacca
     3961 tgatggtaga tttgggagaa actttatatt ttgctgctgg ttctgataaa aatatcaaat
     4021 tgacaacaac agatgatcta gaattgttca aagcatattt aaaaatgaaa gactaggtga
     4081 aagatgatga cgttgattaa acaaccaatg taccaagaag atttggcaaa agtaatcaat
     4141 catacaccaa aaataaaaca gctacatgga aaatccgttc tgatgattgg tgcttctgga
     4201 atgatcggct cttttttgat tgatacgttg atggctgcta atgaacaact aggcatcaaa
     4261 atcaaagttt atgcaatggg cagaaaccgt cagaagcttg aaaaaaggtt tgccagttat
     4321 cttgaattag atactttcga aattgttgaa ggtgacgtca cagaaccctt accaaaagaa
     4381 attcaagctg actatttgat acacggtgca agtaacacac atcctaaggc ttacgcaact
     4441 gatccaatcg gtacgatcat gactaatctt gcaggtacag agcaagtatt gaaacatgca
     4501 gtagcaaccc aaccggttag agtattattt ttatcaacag tagaaatcta tggcgaaaat
     4561 cgaggcgata tagaaaaatt cacagaagat tactgtggat acatcgattg taatacactg
     4621 agagcaggct accctgaagg aaaaagagtc agtgaatcat tatgccaagc ctacatcgca
     4681 aaacacgacc tcgacatcgt gattccaagg ctttgccgta cgtttggtcc gacgatgctt
     4741 ttatctgata cgaaagcatc ctcacaattt attttaaatg cagtcgaaca aaaagatatt
     4801 gttttaaaaa gtgaaggaaa ccaatatttt tcgtatgtat atgttggaga tgctgtttct
     4861 gctattcttc atttactgct tgaaggagaa aaaggagagg cgtacaacgt ttcttcagaa
     4921 aactttgatt tacgactaaa agaattagcc caacagctag ctgatatcag cggcaaacaa
     4981 gtaatttttg aattgccgga tgagattgaa caaaaaggtt tctcaaaagc tagcacagca
     5041 gtacttgaaa ataaaaaaat taaagagaca ggttggaaac caatttttcc tttgaacgaa
     5101 tcattggttc atacagtaga attagttaaa ggtgagaaat ataatgtgtg agattagtat
     5161 tattgttcct gtgtataaag ttgaaaaata tttaagaaaa tgtgtagatt cgattttagc
     5221 ccaaacattt actgattttg aagttatatt agtagatgat ggatctcctg acaatagcgg
     5281 gaaaatctgt gatgagtatg ctgaaaaaga taatcgagta cgtgtgatcc ataaagaaaa
     5341 cggcggatta agcagtgcta gaaatgcggg gattgatgtt gcgagaggca aatacttagg
     5401 ctttgttgac agtgatgatt atattgatga agatatgtat gaaattttgt atgagaattt
     5461 gaaaattcat gatgccgaca ttagctctgt tgaattgatt cctttttatg gtgatagata
     5521 taagaaagct aataaagaaa agaaagtaat tatattaaat aaaaaggaag caataaaatc
     5581 tgttttagaa ggaacgcaat tttatgcata cgcatggaat aaactttatc gtaaggaact
     5641 ttttaaagat aatcgttact tggatggaaa
//
LOCUS       DAZKNV010000113         5409 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000113 DAZKNV010000000
VERSION     DAZKNV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.116"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            236..1111
                     /locus_tag="ACG8M1_002736"
     CDS             236..1111
                     /locus_tag="ACG8M1_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0423388.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1215..1979
                     /locus_tag="ACG8M1_002737"
     CDS             1215..1979
                     /locus_tag="ACG8M1_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFQ0423389.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            1966..3408
                     /locus_tag="ACG8M1_002738"
     CDS             1966..3408
                     /locus_tag="ACG8M1_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0423390.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            3419..4749
                     /locus_tag="ACG8M1_002739"
                     /pseudo
     CDS             3419..4749
                     /locus_tag="ACG8M1_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            4762..5220
                     /locus_tag="ACG8M1_002740"
     CDS             4762..5220
                     /locus_tag="ACG8M1_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFQ0423391.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
BASE COUNT         1834 a          779 c         1124 g         1672 t
ORIGIN      
        1 tttcttatag agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc
       61 gatacaagta ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt
      121 aaactatttt tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg
      181 gttctttctt aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa
      241 ggagtctgca agttgttttg ttttatcata tagtggaggt gaattaacgg tgtatgtgat
      301 gaaaaagctg aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat
      361 ggggaaaggg attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga
      421 caaattattt gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca
      481 gattccaatc gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat
      541 ctcctctcca ttagattcaa atatctatat tacattgaca gatcatattt attttgctat
      601 tcaacgaaaa agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct
      661 ttatccaaat gaatatgata tagcaataga agtggtcgag cgaatcaatc atcgatatca
      721 aaccgagtta gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct
      781 aggagagcct aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc
      841 ccatctagaa aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt
      901 aatggttcat atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga
      961 aaatattggt ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa
     1021 gattaaagat atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta
     1081 tttggcaatt catctagcac gaatctatta aaataagggc gtaactatct ataggcgcaa
     1141 ccaaatgaca catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa
     1201 agaaggagaa tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg
     1261 gtgtgaatta tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga
     1321 tggcaaatat gccgggtttc gagcacgctg tgaaactaag aaaggaaatg cctaggctag
     1381 gtgtaggagt ccatttaaca ttgacgtgtg gcaaaccact tctcaaaact gtcgatactc
     1441 ttatcgaaag cggagagttc agatccttat cttattatca gcatccattt aacattgaca
     1501 aagatcaact gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca
     1561 taccaactca tttagacagt catcatcata ctcatacttt ggatgaaaac caggaggtag
     1621 ttgttacatt agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg
     1681 aagttcgtca tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa
     1741 aaaaacgaca aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga
     1801 gagaagataa aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa
     1861 atggttcaag ttttgtgtat cctcgtactc accaagtcga atttttaatt cattcagcat
     1921 ttgctcaaaa agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat
     1981 agaggaggaa taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta
     2041 cttccagttg cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgatgatatg
     2101 ctgaacatcc cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta
     2161 tttgctatag gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt
     2221 actggttttt tagcgattgc taccttgaaa aaaggcttag aaatcatgga cccagaagtg
     2281 aatatgggga tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc
     2341 tttaaagaac aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg
     2401 actatggtga tgattctaca aacaatcgca gctatttttt tgggctttat ctggccgctc
     2461 atccaaattg ggattgataa ttttgcaaaa ctgctcgttg atatgggggc attaggtgtg
     2521 gggatattta tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat
     2581 acgtatattt attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga
     2641 gagatgacac gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt
     2701 gtagtaatga tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa
     2761 gaaaataaag agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca
     2821 aatatcactg agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc
     2881 catgcacttt ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt
     2941 tttacattcg gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct
     3001 attttgattc ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat
     3061 ttgatcaata agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat
     3121 gaagtaacct tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca
     3181 acaaaaatgc tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat
     3241 acacgcctac gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa
     3301 ttagggataa gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta
     3361 gaagtgactt atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat
     3421 gatgatgaaa aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat
     3481 cgttcaagcc attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga
     3541 tattgatgaa gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaaaaaa
     3601 ggtttttcaa atattcgcat tcgtgcaacg gatgatccaa agcttgcttt tacaggatgc
     3661 gattttgttt tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa ggacgaaaag
     3721 attccactta aacatggatt agtaggacag gaaacgtgtg gactcggagg atttgcttat
     3781 gggatgcgct caatcaaagg tttattggaa attgtcgatc atatacaaga ctatgccccc
     3841 aaagcatgga ttttgaatta tacaaatcca gagtcgatcg tttctgaagc tgttcgtcgt
     3901 aaatatccga atgtaaaaat gattaatgcc tgtgatatga ctatttcaat tgaagaaacg
     3961 attgcagtga attacggtta tgatcgtaag aattggatcg ttacgtatta tggtttaaac
     4021 cactttggct ggtatacatc gatttatgat aaagaattgc aacgagaaat tatgccagag
     4081 attattgaaa aactaataac aaaagaaatg caagtcgccg attttaatat aggagacaaa
     4141 acttggcaaa aaacctttca aatgatgtca gtcatcacga aaaattttcc aagtaatatc
     4201 ccgaataatt acttagagta ttacttatat cctgatatgg tcgttgagca tactgacaaa
     4261 gagtatacac gtgctaatat ggtcatggat ggacgagaga aaaataccaa agaaatggct
     4321 gataaaatac gccgcggtat tgtggaagaa gtattgaact ttaattttgg ggagcatgga
     4381 caatatatcg tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg ctttatgcta
     4441 atcgttccta atcaaggggc gattccgaat ctacggtcag atgcagttgt tgaaataccg
     4501 gcatatgttg gtgcaactgg tgtggagaca attacactaa gaaaaccaat cagtgatttt
     4561 cataaaggat tgatggaggc acaagttgca gcagagaagt tactagtaga tgcttacttt
     4621 gaaggttctt atcaaaaagc tttacaagca tttacattga atcaaaccgt accaaatgcc
     4681 agagtcgcaa aaaaaatact agatgaaatg atcaaagtaa acaaaaaata ttggccagca
     4741 ttaaagtaga ggtgataaaa agtgcatttc tttaaaacaa gaaacattct aaaagctgta
     4801 gctagtggtc aaattattcc attaacagca gtaaaagacg aggtcttttc ttcaaaaatg
     4861 ataggagttg gatacgctat aacgaatcat gatggatata tccatgcgcc agttaaagga
     4921 ataatcgata atatatttcc tacccgacat gccataacga tcgaaagtga atctggcaga
     4981 aaaatactga tccatatggg tttagataca gttgaactcg aaggaagtcc gtttcagata
     5041 cgggttgaaa gtaaccagga ggtaaaagaa gggacactgt tagctattat agatttgaag
     5101 aagttggagc aagcacaaaa agatacggtg atcattgtag tttctccagg catttttgaa
     5161 ggaaatttat taaaacaaaa ccaagaagta aagattaaag atagttgttt tgaattttag
     5221 tgtacgatga aaaaagttaa atagggtgat atttatgggt gaatttacaa aatttttttg
     5281 aaatgataag tttcaatcac tagatttaat cattttgatt tttgttaatt atcgaatttt
     5341 tttgttgctc ctatgattta gaaaacttat tttcaggatt cttaaaaata aatttgatta
     5401 tttaagaga
//
LOCUS       DAZKNV010000114         5116 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000114 DAZKNV010000000
VERSION     DAZKNV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.117"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..299
                     /locus_tag="ACG8M1_002741"
     CDS             3..299
                     /locus_tag="ACG8M1_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFQ0423392.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(822..1775)
                     /locus_tag="ACG8M1_002742"
     CDS             complement(822..1775)
                     /locus_tag="ACG8M1_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0423393.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(1798..2553)
                     /locus_tag="ACG8M1_002743"
     CDS             complement(1798..2553)
                     /locus_tag="ACG8M1_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0423394.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(2550..3509)
                     /locus_tag="ACG8M1_002744"
     CDS             complement(2550..3509)
                     /locus_tag="ACG8M1_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0423395.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(3502..4452)
                     /locus_tag="ACG8M1_002745"
     CDS             complement(3502..4452)
                     /locus_tag="ACG8M1_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0423396.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            4602..5054
                     /locus_tag="ACG8M1_002746"
     CDS             4602..5054
                     /locus_tag="ACG8M1_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFQ0423397.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
BASE COUNT         1706 a         1033 c          868 g         1509 t
ORIGIN      
        1 ctatgaagga atatataaaa aacatctatt ttatcgaaga aacacaaaat atcgagggtt
       61 cttatattga agtaaaaaca ctctttgtca atgaagataa aaccaaagca ttggatattt
      121 ataaaaaatt agcttcaaaa aaaacgaata gttttggatt gatattaagc gagtataaaa
      181 tcaaagcaga agagagttat ttctatcaat tactaaaacg gtggagtaag cttcccgccg
      241 atttttatcg aaaaatgcag atcatcaact atcaaccgct tgctgagaca catgcctaaa
      301 tagaggttgt gaaatcagtg ctttgagcta ataccgaagg tcagctgatt gaacattgtt
      361 tagaagagat tgtgacaact gcgatttgct ttgagtaata agaacgctgg acagaaaata
      421 gcttctcata ttttctagtc tagtggactt attgccgaga agcagcagat ggaacatcgt
      481 ttaaagaaga gatcggtaca aaataaaaat atctaaattt aagttttatc taagtttcgc
      541 tttgtacctt tgattcaaat caaaggaggc gatcttgatg ctgaaaaaat ggatcacact
      601 attttttgcc actccccatt ctagaatcaa cccgtatgat gtagataatg aattcacgtt
      661 gaaaaaagat ttctcaaata aataaaaacc atccgtaaaa tcatcaatac gattttacgg
      721 atggtttttg ataacttctt tgaggatagg ctcttgctat ttaagaatgt aagaaacatt
      781 attgttacat agtatgagag tttaatcctc tgttatttat gctatttaaa tgcttgattc
      841 acatcttcga tcatcagttt cattgattct aaaccgcccc cgcttaaata ccagacatct
      901 ggttcaaggg agatgatctg ctgattttta ccagcattcg tttgtgctac cagttcattg
      961 gcagaaatat catctttgct gtcgtctcca ccaatagctt ttgttctgtc tactacaaat
     1021 aagatatccg gatttttttc cagcacatat tcataagaaa cactttgacc gtgagtggat
     1081 gcttcgattt gatcatctgc ttgttcaaag ccaaataaat catggatgaa accgaatcta
     1141 gaaccagatc cgtaggctga taattgccct tcattcacaa gtgtgactag tgcttttttg
     1201 tcagtagctt ctgctttctt tttcgtctga tcgattgcac tagataattc ctctaattga
     1261 gttttagctt cttcttgctt accaaagatc tcccctaaag cagtgacatt ttgctggaaa
     1321 gattcccatg gatttttcgc atctaaagaa aggaaaatgg tcggagcaat ttgacttaga
     1381 tctttttgaa aatctctttg tcggccagaa atgatgatta gatctggctg aagctgatta
     1441 attttttcta agtctggttc ttttattcca cctgctgatt ctactttttt ataggatgaa
     1501 agatactcag gaaggctgct tgtagctgct ccaactacct tatctccaac accaagagca
     1561 tccatcgtat ctaaagaacc attgtcgaat acgacgactt tttctggatt atttggcacc
     1621 tcgatttggt ctccattact atctgttatc gtcaatgtag tttcagtttg tgtgctgctt
     1681 ttttttgtgt ctgcctgact ggtgttgttg ctatttccac atgctgctaa accaaatgat
     1741 gctagaatca agatacctac tactaatttt ttcatctctt ctctcctaat gttagtttta
     1801 gaaataaaga cagaatctgc ggccttcaat ctcacaaatc cgtatgtcca tttcgtataa
     1861 ttcatccaat acatcttttt ttatcatttc ttgggtcgtt ccttgcgtaa ataactgtcc
     1921 atctttcatt gcaacaattt cgtctgcata acttgcagca aagttgatat catgaagaac
     1981 aataacaatt gttttcccga tttcttgtac taaatttttt aaaatctgca tgatttgaac
     2041 cgcaaaattc atatctagat tgttcaaagg ttcatccagt aaaatataat ccgtgtcttg
     2101 cgctagcacc attgcaatat acgcacgttg gagttgaccg cctgaaagag tgtcaatcga
     2161 ttgatccgct atttcttcta acccaatgtg ttccagtgat tcctgaacga tttcctcgtc
     2221 ttttgtcgtc aattttcctt tcgtataagg aaatcgtcca aattctacta attctttcac
     2281 ggtgatttgg acatttattt cattcgattg tcgtaggatc gataattttt tggctaattc
     2341 attggatttc caagccttta cttcgttatg gtctaaatag atttcacctg tatcttttgg
     2401 tatcaaacga ctgatcatcg acaacaccgt tgactttcca gcaccatttg gaccgataaa
     2461 agcagtcaac ttcttttcag gaatcgttaa ctgtacatct ttaaccactg attttccatg
     2521 gtacagttta ttgacctttt gtaaatcaat cataggatac tcttcctttc gcgaatcaat
     2581 tttgtgacaa aataaattcc tccgacaaat tcaacgacga cactcactgt tgtattccag
     2641 ccgaaaatct gctctactgc gagctgtcct cctgtcagaa acagcatagc taccagaaag
     2701 cttccgataa atagctgacc atgacgataa gtagaaaaga cacgataact gatatttgcg
     2761 acaataaacc ctaaaaaagt aactggaccc acaagagccg ttgatgtccc tgtcaaaaga
     2821 ctgacacaac ataaaatcaa aaattcaaaa cgatctgtgt ctatcccgag gtttactgct
     2881 tgttcatttc cgagatggaa aacgtctagc acatgtcgat atcgaaataa caggtaccag
     2941 cagccgataa tgatcaaaga agcaggcaaa agatactgac tctggatatt gccaaagctt
     3001 gcaaataatc tgccttgaag caaatcatat tcattcggat ccatgatgac ttgtaaaaag
     3061 gtactgacac taccaaaaag cgtacctaaa atcatccctg acatcagtaa taaaaaaaga
     3121 ttcgctctca tttttttcaa aagaaagaaa aataacaata gactcagccc gaccatcagc
     3181 ccaacgttca ataagaaaaa aactgtacct gtctgctgaa gcatcgtcac tcctccgata
     3241 aagaagaaaa ggaccgtttg gacaaggaca tataacgact caagtcccaa tactgaagga
     3301 gtcaaaaact ggttatgcgt aattgtctga aagctgattg tggcactgct gacagctagc
     3361 gagacaagga taaatgcaaa aattttctta ctcctcaatg cacatgcaaa atgccagttt
     3421 ccatatgtat ggatcgtcaa gtacattcct gtaacaaata aaacaagaac aagcatacca
     3481 ataaaaatag atggcttttt tttaagcata tcgtcgtccc cttatcagaa gataaaggaa
     3541 gatagcccca ccgatgattc caacgatcac actgactggt atttcataag gaaaaatcaa
     3601 cacgcgagcg acaagatcgc aaaatactaa gaacaaacta cctgctaaag cagttacgcc
     3661 aattgttttg tgcacttgat ctccatatat tctagagaca agattcggaa tgatcactcc
     3721 gataaaagga atgcttccta ccatgatcaa catgactgca ctagccaatg atactaagcc
     3781 aatgcctaaa aactgcatct tctggtaatc tattcccaga tttactgcaa acgattcgcc
     3841 cagaccaatg atcgtaaatc ggtaagcaaa tagccaaacc aagagcaaca atggaacaac
     3901 agcatacaat aactcataat ttcctcgtat cacagtcgca aaattccctt gaagccatga
     3961 agtcatattt tgtaccaact ggaattgata agcaaaaaaa gtagcaactg aaccaatgat
     4021 attccctaac atgactccaa tcaacggaag catcaattga tttttctgga ggaacaatcg
     4081 cgtaagggat aaaaaaagca atgttcctgc aaaagcaaag caaaatgctg tcaaggatcg
     4141 gacaatcaag gatgcaccag gtaggaaaat catagccact aaaataccta aacgcgcact
     4201 atccatcgtg cccgcagtcg ttggtgaaac aaatttattt tgggtcaaat gttgcatgat
     4261 caacccacaa atactactgg tcgctcccac aaggatcaaa caaatcgttc gtggcaaacg
     4321 agtcactagc aagatttgta agctttgccc atctaactgg agcagttctg acaattgtac
     4381 attcgatact ccgatgaaca atgaaatact acttaaaata actaataatg ctactagtcg
     4441 tccgtagcgc atccaatcca cctttctaat tgagaatgat tttcattctt attttaagtg
     4501 aatcgttgaa caaaagcaac cgctttttca tatgttttag gtattattgg gaatatgcta
     4561 taatcgtaag aaagacaaag agaagaagga gggtattttt tatggcacaa gatgatgtaa
     4621 aaagccattt ggataaggga ctttatggta cacctttagt gaaccctgaa gaacagcata
     4681 aatatttagg gacattcagg gaacgctgct atcttagtat gactgttgct gaaatgatcc
     4741 aaccaaaaaa caaagaaaac tttttaaaag aactcaaaaa acatccagat gcttccatac
     4801 tcttgaatgg ggctctaccc ctttctgtcc aaaaccaata tatccagcta gcaacgaaaa
     4861 acaatagccg tttcactgta gtcaacgatt acgtcactgc aaatcctgag gaattcggat
     4921 tgctcttaac agcaaaagaa gcagtaaatg aacctgtgat tgatatcgaa aaaaaatacc
     4981 cagaagaaaa ctcttcgcca gctgaaaaag aaaaaccaaa aaagaaaaaa agcttctggg
     5041 atcgtttatt ttaaaacgaa aaaacacata aatttttaca tgcaaaaaaa gcttttgatc
     5101 agattgacat caaata
//
LOCUS       DAZKNV010000115         5005 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000115 DAZKNV010000000
VERSION     DAZKNV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.118"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            261..1304
                     /locus_tag="ACG8M1_002747"
                     /pseudo
     CDS             261..1304
                     /locus_tag="ACG8M1_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
     gene            complement(1509..2828)
                     /locus_tag="ACG8M1_002748"
     CDS             complement(1509..2828)
                     /locus_tag="ACG8M1_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFQ0423398.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            3085..3555
                     /locus_tag="ACG8M1_002749"
     CDS             3085..3555
                     /locus_tag="ACG8M1_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFQ0423399.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            3777..4880
                     /locus_tag="ACG8M1_002750"
     CDS             3777..4880
                     /locus_tag="ACG8M1_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFQ0423400.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT         1687 a          822 c         1027 g         1469 t
ORIGIN      
        1 taaaacagca tagttctcaa attgtttaaa atgattgtca agttaaaaaa atctgggatc
       61 atataaaata gtatagttct caaatatgat tagaaaccct attaaagagc aatattaagc
      121 caacttactt aaatcgttta attaagaaca gtaatctctt ttagtcagac ttttagtctg
      181 acttttttgt atttccaaaa tttattcttt acaaaaacga acatatgttt gtataattgc
      241 ttgtgaatgg gggaataaaa atgtttgatt acagtagaga accggtgaat gactattttt
      301 taatcgacat gaagtctttc tatgctagcg tggaatgtat tgaacgaaat ttagacccaa
      361 tgactacacc gttaattgtc atgagtagat cggacaacac tggttcaggt ctgactctag
      421 cttcttcacc tactgcaaag aaaaaatatc atattactaa tgttagtaga gctactgatt
      481 taccttatcc attaccaaaa gaacttcata ttgttccacc acgaatgaac ttatatataa
      541 aaaaaaatat ggaagttaat cagattttta gaaagtatgt cgcagatgaa gatttattga
      601 tttattcgat tgatgaatca attttaaaag tgacaaaatc cttaaattta tttactagtt
      661 caggaacaag aagcgagaga agaagagaat tagctaaaat aatcaaagat gagattcaga
      721 aagaaacagg tctaatagca acagtcggaa taggagataa cccattatta gctaaactcg
      781 cactggacaa tgaagcgaag agtagtaaag aatttatagc tgagtggtct tatgagactg
      841 tacctgaaaa aatatggaaa ataaacgaga tgactgactt ttggggcatt ggatcacgca
      901 tgaaaaaaag attgaatcat atgggaatta tgagtataga agatttagca aattggaatc
      961 cctacacaat taaaagtcag ttaggtgtaa tcggacttca gttatatttc cataccaatg
     1021 gaattgatcg tacggatatt gctattccac cagaaccaac caaagaaaag tcttatggga
     1081 attcacaagt tctaccaaaa gattatacga ggagagaaga agtagaacta gtagtcaagg
     1141 agatggcaga gcaagtagcc attcgaatta gacaacacaa ttgcaaaact ggttgtgtac
     1201 gcttagcaat tggtacgtca attttggaag aaaaatcagg tttctcgcac cagatgaaaa
     1261 taccaattac agataatacg aaagaattac aaaattattg tctttcctga ataattcata
     1321 gctttaattc tttggcacat tttattgaaa tatgtatcac taatatccct atcaactgat
     1381 tttgactaaa aagttacttc aaacattcac tgttcaaaaa tattgaggaa taaattttgg
     1441 gtgtaaggca ttttgagcat acttctccct ggataacttc ccagtaaaaa aatcgttaga
     1501 ttgttggatt agatccattg actggctcgc ctcaggcgag caaagaccct gtagaattca
     1561 ttctgataca catgataact agataatttg agatagactc gtctacccgt ttggactaat
     1621 ttcccagcaa ctttcagaaa cttcaatcga atagaatgaa tggtcattcc cttttggact
     1681 tcttcaaagc caatcgttct taagaagttg actaagttgt aagctatcaa gctgagcatc
     1741 attcggacat gattctccaa aaagcgagga ctgtctgttt tgtcaaagta aaagccagct
     1801 ttcgcttctt taatgaagtt ctccattgtg ccacgtttgg catagataga aaagatggta
     1861 tcaggagaaa cattttctga tagattcgtc acgataaatt catgtcgaaa gagtagttcg
     1921 cccgcttcac gtgttgagcg tatacacacg cgacgacttt gtgaccagga ttgtgcttga
     1981 taagtggtcg agaagtactg aacttctcgt tcttcccact tttgattatc gccataaagt
     2041 actgatttct cagctatttg acctagtcta cgattattct tcagtcgaat aacataatga
     2101 ctcttttttg attcacacga atcatacaca ccaggtgtag cgaacccgct gtctccacga
     2161 accaagatgt cagtgtttgg tagagagtga ttatagtgct ctaataaagg tgtgagaaac
     2221 tcctttacgc cttttgatgt atattgattt cctgaacgta gttcagcttt taagaagtca
     2281 ccagtcaatc cgtcaaaagc taccaatgga tggtaaccat aggtttggta gtgtgtatta
     2341 taattcgttt gttcttggtg accaaatgta tctgaatggg tcgaatctaa atcaatgatt
     2401 aattccgtat cattacggat gaggcgtgct ttatcgataa gttcttggtt caaagcttga
     2461 agttcatgga tattctcctc agatagtcga tctaaaaatc gggaaagtga agattgagaa
     2521 gcgagttctt tcctatctaa aacagcttta aacacaggat cttgtctcag gagattagct
     2581 gcagaatcag ctgagtaacc agcaattaat tgcataatga actgctcaag tatggataag
     2641 ttgtcatgag taaaatacgc tcgttcgtct tcaatgtgaa tgtgttgctt agccagttca
     2701 gaaaaaccaa agatgttcat cagctctttc actaggacga gacccgaatc actcgataat
     2761 tgaccacctg tatgagaaat agtgatattt gaattgaatt ttacttggtt tttgtgtaag
     2821 ctagtcatga aaagaactcc tttcttttgg ttggtttagt cactttaacc atagcagaaa
     2881 ggggttcttt tttcatcact taacgggtga agatgaaaaa gtaattgtaa gctgccgtga
     2941 ggcagtttca catggtttta attaaaagta tgaattattc aggtagaatc tctgaagaat
     3001 aaatcacgtg atcgtgacga taaaatacac ttacgtcagg tgataaaaaa tacataagta
     3061 gaaaactaag aggaggaaca gaaaatgaaa gaagttcaat tgatcagaaa aagcgaacta
     3121 tcagaaggtg gttgcaatgc atgcggcgta gtagaagcaa caagctatac attaaagctt
     3181 ggtgccaaca aagcgataat ctctgagttg acagtaggcg gtcttgtgga cagtctggcg
     3241 cttgctgaag gttttattgg agaagatatt tatgagatgt tttcagaaat ccgtcagtta
     3301 aaaaaagggg aaaactgcat agaggttcat catgagagcc cgaatgtgag attcaaacgt
     3361 ggtgataatg agatgatctt caataatcat gtgtccgatc acaccgagct atatggaatc
     3421 gtgaatcaaa tactaactga gctttttgga ttgggacctt atgcgttcaa ggaagaaaac
     3481 ggtaatccaa aattaaacga agaatggcaa gaaacgattg aaatacaaag aaacaacccg
     3541 cacttatttc aataggcatc cacagtattt cgtaaaaggg actttgacac gacttttgtc
     3601 aaaatcccat cgttttttat ctatttgtgt tctaaacatt tctttcagag tagtaacaac
     3661 tggaatgact gaaatgtaaa cagattattt gcctgtatca atacggaaga gtaatataaa
     3721 gtgtgtaaac gctatcatat tattcattca attttttata gagggaaggc attgaaatgg
     3781 aaaaaacgta tcaagcaggt acaaatgaag gaatagtgga ttttatcaat atggaagatt
     3841 tagaaatagc cgcttcacaa gtgattccag ctggtggtta tggttacatc agcagtggtg
     3901 ctggcgactt atttacttat caagaaaatg aacgggcatt caatcatcag ctgattattc
     3961 ctcatgtatt aagagatgta gaattacccg atacaactac acattttgac aaagaaacgc
     4021 tgactgcacc aatcatcatg gcaccagttg ctgctcatgg cttagctcat gtgaaggcgg
     4081 agaaagcttc tgcaaaaggt gtagcagatt ttgggacgat ctatacagca agttcttacg
     4141 cttcttgtac attagaagag ataagagaag caggcgggga gaaagcaccg caatggtttc
     4201 aattttatat gagcaaagat gatgggatca atttggatat tcttgaagtg gccaagcgta
     4261 atggagcaaa agcaatcgta ttgacagcgg atgcaacagt tggcggaaac cgtgaaacag
     4321 accgcagaaa tgggtttacc ttcccactgc caatgccgat cgttcaggct tatcaatcag
     4381 gagtaggcca aacgatggat gctgtgtaca aatcttccaa acagaagctt agtccaaaag
     4441 atgtagaatt tattgctgct cattctgatt tgccagtcta tgtgaaaggt gtccagtcag
     4501 aagaagatgt ctatcgttca ttagaatctg gtgctggcgg aatctgggta tctaatcatg
     4561 gtggccgtca actagatggt ggtccagcag cgtttgattc gttgcaatat gtggcagaag
     4621 cagtagataa acgtgtacca atcgtgtttg acagcggtgt acgacgcgga cagcatgttt
     4681 tcaaagcaat cgcatcaggt gcagatcttg ttgctattgg cagacccgtt atttatggat
     4741 tgtctttagg aggaagtaca ggagtccatc aagtgtttga tttctttaaa acagaattgg
     4801 aaatggtcat gcaattagct ggaacacaaa cagtagaaga tatcaaaaaa ataaaattgc
     4861 gtgagaatcg ttttatttaa gaaacaaatg acgaaaaaaa taggagtgcg gcagatgatg
     4921 ccgtactcct atttttatag ttcaaggatg tcactaatag aataatttga aacgaaaaaa
     4981 taaaattgaa atattttttc atact
//
LOCUS       DAZKNV010000116         4971 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000116 DAZKNV010000000
VERSION     DAZKNV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.119"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(71..1270)
                     /locus_tag="ACG8M1_002751"
     CDS             complement(71..1270)
                     /locus_tag="ACG8M1_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFQ0423401.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1400..2776)
                     /locus_tag="ACG8M1_002752"
     CDS             complement(1400..2776)
                     /locus_tag="ACG8M1_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0423402.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2776..3432)
                     /locus_tag="ACG8M1_002753"
     CDS             complement(2776..3432)
                     /locus_tag="ACG8M1_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0423403.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3442..4719)
                     /locus_tag="ACG8M1_002754"
     CDS             complement(3442..4719)
                     /locus_tag="ACG8M1_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0423404.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4738..4899)
                     /locus_tag="ACG8M1_002755"
     CDS             complement(4738..4899)
                     /locus_tag="ACG8M1_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFQ0423405.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
BASE COUNT         1566 a          901 c          609 g         1895 t
ORIGIN      
        1 gagatgatct tgaggaacta gatcatcaat cgtaagcatc gcaaattgat ttctaccatt
       61 cgtattgttt ttagacatca tagctatcac tccttgcatt cgttttcata aatctattat
      121 aaaagaaaag actgtagaca tcatccataa aatggacttt gtctacagtc tgcgcattct
      181 cattagagaa cactcccttt tttgtgactt ttctgaagct agagtgaata ctttcaactg
      241 cattagtagt gtacatgatt tttctaatgg cgctgccata atcaaagagt tgttcaacat
      301 gagaaaagtt tcgtttgcat acatctactg caccagaata atgagaccac cgattttgaa
      361 aactgtcgaa ggcagcgtgt gcagcgttta aagaagaagc actgtagaat tttttcatgt
      421 ctcgacagac ttccttataa tccttacttg ggaggtatcg taacgcattt cgaacaagat
      481 gaacaataca gcgctgcaca atgacagaag gaaaaattgc ttttgcgcct tctttgagac
      541 cggaaacacc gtccatcgaa atgaaaaaaa catcttctac accacgtact ttcagttcat
      601 caaatacttg catccagcga tttttagatt ctgtttgatt gagccatagg cctaaaatct
      661 ccttgtttcc tttaagatca tagccaagaa tggtgtacac agcatattct ttagcttcat
      721 agttttcgcg taaagtgacg tacatacaat caacgaatag aaatgcataa cacttggcta
      781 atggccgagc ttgccattct tccaattcag gaaggacggc atccgtgata tcagaaatca
      841 tttcgtggga aatatcaaag ccgtaaatat cttcaacggt tgcggcgata tcgcattgac
      901 tcattcctcg tgcatacatg gaaagaacct taccttcgat gtcggagaca tctcgttttc
      961 tattaggaat caactcaggt tcaaaagaag cctcccggtc tctgggaaca tcaatgttta
     1021 ctttaccaaa gctcgtttta agcgtcttat tgccataacc gtttcgtcga ttgtcatgtt
     1081 tctttggctc tttagaatgg gcgtcatacc ctaaatggtt attcaattct ccttgaagca
     1141 ttttttcaaa taagggacca aacacatctt ttaaaacatc ttgcatatcc tctacagatt
     1201 cgggttgata agtattcaaa atggattcag ctaacttctc agcatcagga tttcttttct
     1261 ttctagccat cgtgtaatca cctcttgatc ttattttaga aaaataaaaa ccgtgaagca
     1321 accacccgcc taggattgat ggttacttac acggtttata ttacactctc atttttggtg
     1381 ctaaaaagca ccgaaaattt taattattgt caattaataa ttcttttgga ttccttctta
     1441 atatattgaa tgaagaaata atcaatgata caagaagtac taaactcata aatataacta
     1501 cataaatcat gaatttaggt aatacattga tatctaaact tgataatgtc ttgttaaatc
     1561 cttcagcttc tgccccacca cctaattggc tagatgcaga ttgtttagct atttgtttag
     1621 ctatatcacc agtaacctta ttcaatatat tattcccaag cttgtcagct gtatattgag
     1681 ctaagaaata ggaaccaacg aatgcgggga ttgatataaa taccatctca attaggaatt
     1741 gaccaaaaat ttctaatttt gatataccta atgatagtaa tactgctatt tctttctttc
     1801 tagcattcat ccataagaat aataataatg aaactacaac tcctgcaaat attaatgagc
     1861 caaaaaataa tttatttgaa attgagtaaa tacctgatat agattgttgt aatgcagggt
     1921 aatttgatga acttttaatc aaattatatt ctctccaatt tatatctaat ttcccaagat
     1981 cttttattac actatcaaga ttcttatcac cttttacaaa gaatgttgca tcttggtata
     2041 cagctgtatc ttcggtatta ccataaactt tagcagctgt atgaatatca gtgattaatg
     2101 tattttcgta tagttcttgt gctgcactta ctccaccgct attatgccca tcgaatagac
     2161 ctttaatttc tacttctact gtttcatctg cacctttctc attatcagca tcaaataaat
     2221 tagattttat ttttatctta tctccaactt taaggttatt tttttcagct aaatctttat
     2281 gcattaagat tttattttta tcttcatttt ctaaatgctt tccttctact aatttatatg
     2341 cttctgatac aaattttgtt tcttttgttg agtcgttaac cccagttaac ataactgttc
     2401 ttttaaaatt ctttgctctt tcaggtgatt gattcgcaag agtctcttga gtttcaataa
     2461 tatcataatc aactaaatct gcaacactgt ttattctttt tacataggag tctatactat
     2521 ctgtttgaga tatcttttta atatcttcac cttttacatt tcccccacct ctaggtgttc
     2581 ctggatttac ttgtctattt atctccatag aaaaactatt tgttatatta gcaaatgttt
     2641 cttttgaagc tctgtccgta gcatctttaa tagataaact aatgagactt aaagttgaca
     2701 tagataaaat aactaatatg ataattaatg attttaaact ttttctagtt acataagcaa
     2761 atgcattttt tatcattatt caacctccaa attcatttta tttacttttt tcaacttttt
     2821 accacttagt tctaaaatga tatccgcaga atctgctact tccttactat gtgttacaac
     2881 tattacacat ttatttctat ctttagctaa tgtctttaat atattaatta tttctccagc
     2941 agtaacactg tctagattac cagtaggctc atcagctagt attattggag catctgatac
     3001 caatgctcta gcaatagcta ctctttgttg ctgtccacca gataatttca taacatttct
     3061 ttttatttgt tttttatcta aacctagttc aaacaagata ctttcatctg ctgatttatt
     3121 tactaatcta atattttcaa ttggtgataa ataatctatt aaattatagt tttgaaatac
     3181 taaagatata ttattttttc tatgattact atatccttta ttttgtatat cttcattctt
     3241 aaacaatatt tttcctgttt gaggtttatc aagtccagca agtaaggaaa gaagtgtaga
     3301 ttttcctgtt cctgactttc ctactatcgc ataaaacttc ccaagttcaa atttttgatt
     3361 tactcctgac aaaacttttt ctttagaatt tgcataacta tatgctacat tctttatttc
     3421 taatatatcc attattttct cctaacttat ttttgataag atttctttag gcttcttgat
     3481 taacattaat gaagaagcaa atacaactga taaaacaata atacttatta atattaaata
     3541 actttgtcca agtgttgtta tatttgacat aaaactacta ttatttatta aacttccacc
     3601 ggaaatcatt gaatcctctg agttaatgaa tccatctaca attactttta gtaatacatt
     3661 tcctaaaaat aaggaagata ttatacttgg tatcgatatg aatattaact cgaatataaa
     3721 ttgcattata atttgtatct tagatgttcc aatagataag aatataccta tttcataaat
     3781 tctttccctt aaccatagaa tcaagattaa tgaaagaaca accatcccac ctaacataat
     3841 agaataagtc attactttta ttatatattt tattccactc actgactcta aagactcttc
     3901 aaacgcatta gaatcttttt caacaaaata ctttgactca tcaattttaa gctctttcaa
     3961 tttgtttaag gctaagtctg tagattctgc actaccagaa tacattaaaa ttttatttgc
     4021 aatttcatta ttttctgaat tatttaatat ctcttggctt gttgaataat ctacaaacac
     4081 catattttca ctaaaatcag aagataatcc tgtatatgtt tcctgttttt taccagaaaa
     4141 gatccctata attttaaatt tatgactttt tatttttcca cttttttcaa tatctagtaa
     4201 ttcaagatca acttcatcac ctaattttag attgttttgt ttagcaaatt cttcatgaac
     4261 aataattgaa ttcttatcat tttcttctat atttttacct tctttaattg taaatactcc
     4321 actactaaat aaaatatttc ttttagtatt atttgtagct tcgagtgaaa caacattctt
     4381 aaattcgtca gataaatctt ctctatttat tctttgttct ccgctaacta ctttagcatc
     4441 ttttagtttt gctaatccat catattgaat tattttttct tcaatttctt ttaatttttc
     4501 aatatcttta aattgattaa cattaaaata tttaccatct ttttttgtta ttgatattga
     4561 agaattagaa ctttcatata aagccttttc tatttcattg cttgatttca ttattgttaa
     4621 acaagaatac aagcaagaaa gaactatagt taatatgata aaaattatta aagttctatt
     4681 tttctttctt gtaatatatg ctatagcatt ttttatcact ttcctaacta ctcctctcta
     4741 ttttcttact ccataactaa ttgcatccac tggacaagca tttttacatc gtccacatct
     4801 gatacactcc agatgattgc aattctcaac tgaatcttta ttcatttggc aaactttttt
     4861 acattttcca caattaatac acttatcctt atcctgaatc ggctacacta gactagacag
     4921 aaaaaataag gtgtgtagaa taataaaaaa cacactggag gatttttcat g
//
LOCUS       DAZKNV010000117         4812 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000117 DAZKNV010000000
VERSION     DAZKNV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.120"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(92..1177)
                     /gene="xerS"
                     /locus_tag="ACG8M1_002756"
     CDS             complement(92..1177)
                     /gene="xerS"
                     /locus_tag="ACG8M1_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFQ0423406.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            1526..1721
                     /locus_tag="ACG8M1_002757"
                     /pseudo
     CDS             1526..1721
                     /locus_tag="ACG8M1_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            complement(3253..3771)
                     /locus_tag="ACG8M1_002758"
     CDS             complement(3253..3771)
                     /locus_tag="ACG8M1_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFQ0423407.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            4138..4386
                     /locus_tag="ACG8M1_002759"
     CDS             4138..4386
                     /locus_tag="ACG8M1_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423408.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         1580 a          787 c          732 g         1713 t
ORIGIN      
        1 atataaaaat gataatgaag cttgccttta aagttgggct tttatctaat tttagagaca
       61 ggcttcatta ttatactatt ttttactaca tttacaaagc gttcaaagca tcaattgtag
      121 ctgcattgtc tatatgagta tataaagttg ttgtatttgt acttgtatgt cccaattgtt
      181 gggcagttaa taccaatgaa tttgtctgtt gatagagtct agtagccaaa gtatgacgta
      241 atttatgtgg actgacttgg actctgaatc cttttgaata ttttgctacc atccgttcga
      301 ttgcaatacc ggatatacgc ttggcttctc cttgataaat tgctagaaat aaagcttttt
      361 cgttttctgt tactttgtat cgttctttcc gaatagctag ataattagct aaatattcca
      421 ttgcaaatgc tgctatattt actgcgtctc tcttatttcc ttttctagtt actaccacat
      481 tattcttttc taaagatagg tcctctaaat taatatttac aacctcggag agtcttaatc
      541 cagatcctaa aatcaatgca ttgatcgcca ggtctctttc tacatctcgt tgataataga
      601 tcaaagctcg tttgctcaaa gtttttttat attcattggc aatataatct agataatttt
      661 gtgtatcttc gtctagaaat aattttttct cgattgcgtt tgcacgggca gctaacgtag
      721 ttttatctgt gatagttgct acttgatcca taggattatt ttctaagtat ggttttccta
      781 aaggattatt ggaacttttc gaaagatatt taaatagaac ctttaatgct gtgatatttc
      841 tattgatagt agaagtagat agacctaagt tattattatc tttgagctta gtttttgttg
      901 tctctttttt tacattttcc tttgtgcgac gtttcaaatg agatttgtac aagtttagat
      961 cataggcagt taactgtctt atcgaggtga ttgaagtatc gggaacgata gactcactca
     1021 gaagccattc ataaaagagc ttataatttt ttagatattc taaagtagtt cgaggtgatt
     1081 gatctttatc ctcacgatct tgaacaaaat cttttatata atcgggcata tgaagtatga
     1141 ttgtatctat tttttgatat atttctgtat ttttcatgtt attcatcctt tcgataagta
     1201 ggggagagga gtatctctat aattggacta taccaattat agagtgtttt gtcaattggt
     1261 atactctgaa atttattaat ttatttcaaa aaagcagata aataggtata gatttaataa
     1321 tttaaaataa atggtataca tgaataggaa aggaaacaga aggaggcaat cttaattttt
     1381 taaattgtct aaattatata gaaagaacaa tctttctata taattagaca taagagggac
     1441 tacggttgat ttgatattaa caagcgtata tgaatgtata tacaaataaa aaaggggagg
     1501 gagaagttaa agaaaattca gagaagtggg gcactcagta gtattaacaa tttaaaagga
     1561 atttcttaaa gaaaatgggt tgcatcctgg agatacaatt tttttagata aagaaaaaat
     1621 tcaagcaaca attcaaaaaa atcttaactg ctgagattga tgtagcaata tctcaatcat
     1681 caacaaagta cgatcctgcc tttcaaaagc ttattgataa atgtttattc attataaaaa
     1741 taaaagaaaa atttatgtca gcttttttca tcaaagtggt aatgataatt cgtctattaa
     1801 ttgtattttt taggaaatat ggtataattg ttttaacgaa aaggtaattc atgatacacc
     1861 aaaaaccact agctggcggg ctagtggttt tcttttacgt tctattcaga ttaacgggta
     1921 ggcttactgt cttttttggc aataattttg caatcaagcc atttacagat gtaatgcgcg
     1981 gatacttctg ctaagattgc aaaaaacata tcgaaaaggt aattcataat acaacctcct
     2041 ccccttgcca taataggccg gggtagcaga cagcataaat attataccat aactgaaaat
     2101 ttcattttag tacatttcaa tatattgatg aaccagcaca ataaaacatg ccatgactaa
     2161 cagaaaaaaa cttattaaac cagatataac ttgtaaacat ccaactatat agaaaacgta
     2221 aattttctat atagttggat taagataacg actatttatt ttatcatatt tttactatac
     2281 cctatacttt tacttggtat atttatgaat aatcgcaaat ttacccctat actactagtt
     2341 tgtaagttag attaataaaa atactaaagt tatttgttct tttattaaat acacctacaa
     2401 cttataaatt gatggtattt agataacacg aaagaataaa aataacagct gatagtaaag
     2461 tttgttgacg attgctactc aatcgaaagt gagttagtgc gtatgaactt gcttctgaaa
     2521 acttatgaaa tgaaagacct tttacatctt gcagaaatcg gtactgggat taaactaagc
     2581 aataaaaact aatgttcccc tcattctttg aacttctact atttgattta tttattctga
     2641 taaatgacga tttcaccttc aggatcttca aatcccgtat agaatttatt taagatctct
     2701 tcagtatcag taataggata ggcgataggc cacataccct ttgatggtta gaataaactg
     2761 ctcaaaatct gtatcgtatg ttggctttag catattaaca aaggctatct ccaaattata
     2821 aaccataagc gttgaatcgt tcttaacaat ttcaattctt cctaacccaa agtcagaaga
     2881 tataattacc ggacttgcct tacccttcat gtgggttgtt gagattccat atttaaaggg
     2941 aattgtcggt actatcggcg gtctgaaaaa catcccaaaa ataaaaaaat ctttcccctg
     3001 ctagtctcct aagtcccttt gtagcggata tggcaccata atctcatttt atcgaagtga
     3061 gtcatggttt atctgttggc caaccaaaat tgatacaatc taacgatgca ccctctacgg
     3121 cattctaggg gagtgcactt gcattcaccc aataaaaacc ggcagttagc aaagaactta
     3181 tgtagtcgta tgttcttact gttaacatac aagaggtctc ctttccacaa ttgcttagca
     3241 gtaaacggga atttacaaag ctaatctctt ccattttctt atctttgttc taaaagtccc
     3301 aaatggagca actgtattta catgaataaa tttatatact tcccatacag ccgttttggt
     3361 tgcctcgtct gcccattttc ttttgtgtgc agtgaataga tcttcatcac tcattgaatc
     3421 aatcatcatg ttaatatcat caatattacg attgagaatt tcctctaatt ctttcaatgg
     3481 tagatgtgca taggtatttg taaaccactt atataactct cctaactgat tccatttaaa
     3541 ttgatcagaa ggcgttttaa cagataatcc atttctttca tcattttccc attttagaat
     3601 taaattcgtc caaccaactt gatatgctaa attttcagca ggtgttctat ccacttcctc
     3661 aactctttta tccttcaatt cttcaggaat agtttcaaat tctaaaatat atttagtata
     3721 agtcctattt atttcttttt ttaattcttc tttattttta tatgttctca ttatattacc
     3781 tccataaatt cctaattgtc tcctttaatt catctataat ttcatccacg atattttaat
     3841 ccgttctaca atgcatatct gatatgcatt gactgtctaa ctcatatgtg aatgatttat
     3901 aaaatatccc aacgtctcat ctaaagaaat gttgatcgtc agcaaggagc taaaaaatac
     3961 gaatatattt cttttgtagt aaaatcggac tggtttgcat atcattttct tcgtaaatat
     4021 caaaatcatg ttaactacta tcaattacta ataaaaacta ccactttaag cgttaagaac
     4081 tgttaagttt agttaagtga ggatagttca caaaatccat tgttaaactt cacgaaagtg
     4141 gtaaaactca aaatgcttta tataggatta cagcatcgct ctttcttcga ttgcgcgttg
     4201 ggtaaaaaat attatgaagt aaaaattgac gatgacacgt tccttacggc tcatcagatg
     4261 aaacagctac aaaaacgaaa tgatcaactc gaagaaaatt taattctaaa aaagcgattg
     4321 ccatattcac gcctcgctcg acgaactatt aaaggtcaag atttacctga agatcatcct
     4381 ttttaggaaa ttgaagcttt ttatgttgca caatgcattt ataatactac aatgatgttt
     4441 tcaccagata ttcttctagg gtgcggtgta atgaaacaga tacacttgca aaagaaaatt
     4501 caccgcgaat ttactaaaat tatgaataat tatgttaatc ttccgaaatt tttttccaaa
     4561 attaagggat caagctggtg ttatagattg tttaaggttg gcaaaaaaat aacttctttt
     4621 taaacaatta tagaaaaccg atactctgtt aagttggttg acacggtgtc gatttttatg
     4681 actttcttat tctgaaactt cactaacgga cagtacctaa aaagtctata gtatggacgt
     4741 ttacgagtac tattttatca aaaatgctgc tcatttcaac ttatatgttt tagtgaacta
     4801 cccccactta gc
//
LOCUS       DAZKNV010000118         4796 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000118 DAZKNV010000000
VERSION     DAZKNV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.121"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..527
                     /locus_tag="ACG8M1_002760"
     CDS             <1..527
                     /locus_tag="ACG8M1_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0423409.1"
                     /translation="KQYRTKGIAYFSKEDFHELLDIPKSYRESVINKKIIKPIRQELT
                     AIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEEQNKALELVNQQI
                     YSEKDPTSLQEKIKEQKRKLELLQQLEELERKQNNLNKENKEINEQIPDNNSDIPPEL
                     KKGLLDNLQNLFKE"
     gene            537..1034
                     /locus_tag="ACG8M1_002761"
     CDS             537..1034
                     /locus_tag="ACG8M1_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFQ0423410.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNIIYLKKE
                     AVTTITKVLSGNEPGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQLALETQ
                     QKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQSKTEKKW
                     WQFWQ"
     gene            1410..1691
                     /locus_tag="ACG8M1_002762"
     CDS             1410..1691
                     /locus_tag="ACG8M1_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423411.1"
                     /translation="MDILVRKIDSKIISEIDRRCQELTTKTSKKWSRNTYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNEYVRTNNQLIETLIGGL"
     gene            1693..2109
                     /locus_tag="ACG8M1_002763"
     CDS             1693..2109
                     /locus_tag="ACG8M1_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423412.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISILSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNHQKETNQTFTAGNFDPTNFLKR"
     gene            2767..3192
                     /gene="bacA"
                     /locus_tag="ACG8M1_002764"
     CDS             2767..3192
                     /gene="bacA"
                     /locus_tag="ACG8M1_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin 51 precursor BacA"
                     /protein_id="HFQ0423413.1"
                     /translation="MICKNKKKIIAIIASFSLIFSTACTVLLTNNANVEAASSSYKHN
                     HAGYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPGIISLVFGSAVSA
                     NNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            3222..3386
                     /locus_tag="ACG8M1_002765"
     CDS             3222..3386
                     /locus_tag="ACG8M1_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423414.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
     gene            4346..>4796
                     /locus_tag="ACG8M1_002766"
     CDS             4346..>4796
                     /locus_tag="ACG8M1_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0423415.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRL"
BASE COUNT         1745 a          816 c          804 g         1431 t
ORIGIN      
        1 taaaacaata cagaaccaaa ggaattgcct atttttcaaa agaagacttt catgaattac
       61 ttgatatccc taaaagttat agagaaagtg ttataaataa aaaaattata aagcctattc
      121 gccaagaact aaccgcaatc ttcaaaggtc tgacaatcaa aaagaaatac ggaaaaggaa
      181 gaggaaaacc tgtcattggc tatcaattca cgtttaaacc tgaaataaaa aaagcagacg
      241 actttaataa acacgcacca acaaaagaag aacaaaataa agctttagaa ctagttaatc
      301 aacaaattta ctctgaaaaa gaccccactt cattacaaga aaaaatcaaa gaacagaaac
      361 gaaaattaga acttttacaa caattagaag agctagaaag aaaacaaaat aatctgaata
      421 aagaaaataa ggagattaac gaacaaatac cagataacaa ttccgatatt cccccagaat
      481 taaaaaaagg cttactagat aatcttcaaa acttatttaa agaataaggg gtttttatga
      541 cagataaaac tatcaaagaa ttagcagata ttctaggtgt ttcaaaagat aaagtgaagt
      601 atcaactgag gaaattacct agtaatttta cctacaaaaa aggaaatatt atctacctga
      661 aaaaagaagc agtaacaaca attacaaagg ttttatcagg taatgagccg ggtaacttac
      721 ctagtgaatt acctgattca ttacctaccg attacctact caaggagatt gaaactaaga
      781 ataatcatat tgaagaaaaa gataggcaaa ttgaaaaact tcaactagct ttagaaacac
      841 aacaaaaatt actcgaccag caacaacaac tcaccctgca agccaaccaa caaatcgaga
      901 aactgcagga acaactacag ttgacttata cggaagaatc ttcggaaaat aaatcaacga
      961 ctctttctga agaaacagaa tcgatagaaa aacaatcaaa gacggagaaa aaatggtggc
     1021 aattctggca ataaaaccag caatttaaat taataaaaat tgctggtttt attcttcttt
     1081 ttgcttttgc gagcagagca acatgggccc atgttgcgat attttggtgg cgccccaatc
     1141 cccgtttttt cgttgaatct tactcggact gcactcgttt tacagctgat ttttctgaat
     1201 tttgaaagag cataaggaaa cgtggtatca ctttcttacg aaaggtgcta gataagctgt
     1261 gcctatcacg tttctcagaa aaaaatttgc tatcactttt ttgccattat ggatagtgta
     1321 tgtatagtat tttggtaaaa aacagctata caaatactat atttgtatga tatacataga
     1381 ttatacgcac atgcgaaagg aaaattgcta tggatatttt agttcggaag attgattcaa
     1441 aaattatttc agaaatagat agacgttgcc aagaacttac aaccaaaacg agcaaaaaat
     1501 ggagccgtaa tacgtaccta aaagttctaa tcgaaaatga ttttgaccag gcacttaggc
     1561 attacaaaaa agatcaattc gatttattac tcgaaaaatt tatcgatata caagcaaaaa
     1621 atacggaaac actgaatgaa tatgttcgta caaacaacca actcattgaa acacttatcg
     1681 gaggactata acatgagaaa aacttctgtt caaaaacacg ttacccttta tcccagtcac
     1741 gtggacgttt tagattccat tattgaaaga aatccagata tcaacaatta ctcggaagcc
     1801 attcgttttt tatgtatgag ttatgaacct gataccaaca caaccactac tagcaaccaa
     1861 gccaaactaa atgctatggg aaaagaaatt tctatcctgt ccgaaatcat tgcagaattt
     1921 gctgatttat atctaaaaga tactggtgtt cttattggta ccaattctaa ggtgtatcaa
     1981 gaagtgaaag aaaaaattga aaatcaactc aatccttccc gacgaaatca acccaaaaat
     2041 catcaaaaag aaaccaatca aacattcact gctggaaatt ttgacccaac caactttcta
     2101 aaaagataaa aacagaacct gaaaaataaa aaaattcctc gatttctttt tagggggggc
     2161 ggtcttccag caagatttgc aagttgggac caacttgcgg aaaaaaagaa aaattcgctt
     2221 gcgcgaatcc ttctttttgc attttggggc gctgccccaa tccccaagta tcggttattt
     2281 aatagcgtgg caactcaaag aacagaacat actctgaaac aaaaaaagac tgctctaacg
     2341 agcagccagt taaaaaataa tgagtgttta ttcttgaaaa agcaacgcgc ttatgaagcg
     2401 ctaccaaaaa attatcatat tttattaaaa ataacaaccc agtaaaaaat gactggtaaa
     2461 aattcacaaa gaaacggaaa gaagcaaccg cagaaaatca agcttaaaaa gagcttttga
     2521 cctagaccaa tgaaaaatca caaagtccgc ccctgtacct gttggtagct gggctacttg
     2581 gcatactgta cattatgtca acaagaattt aatataacat atttttctag tttgttataa
     2641 caatgccact ctaacaaaaa tgtaagcatt atccttatta aaagctcctt gacaagacta
     2701 taccttttat tttatgattt ttacatagaa aacgttttct ctattttttg tttagaggtg
     2761 atttttatga tttgcaagaa caagaaaaaa attattgcta ttattgctag tttctctttg
     2821 atttttagta ctgcatgtac tgtcttatta acaaataatg ctaatgttga agctgcaagc
     2881 tcttcttaca aacataatca tgctggttat agatgttaca aaatgagtta ttatgtaagt
     2941 ccttctaaat gcaaacaatt ggctcgccaa actaataaac ttaataccgt ctcagctatt
     3001 gcaaacttta ttggactatc tggattaaca ccggggatta tatcattagt tttcggatca
     3061 gcagttagtg ctaataatgt atttgttaca gccgctagaa gaggaaaagg cgttcaatta
     3121 aattatattg cccattttag taataccact acctataatt atagttctaa ccaaaattat
     3181 gttataaaat aattaaaact ttaaactagg aggaatgctt tatgaaatta acaaaaattg
     3241 ctgtaatttt agctgttatt gctggcatta ttttatattt tgtattgcct gctaatcaat
     3301 tcttccttta ctttggaata cctgcgattt taatagtaaa tggcgtaaga atctttgaac
     3361 aacgaaaaaa atgtagctct acctaatcgt tacaaaacaa caatttcacc ttcggtgaaa
     3421 taagcgaaac tttacaaaaa gtggctagca aatgctagcc ttttttgtat tgtagagcgt
     3481 gaattttgag ggggattcaa gggggagctt gcgccccttt gacaagcggt tatttgcacc
     3541 aaatacctcc gtatttggct agcaatcctt ctaaaaaata cacctatcga tcagagtcaa
     3601 aacaaatcaa ttttcgagtg agcgaatccg aatttgcaaa gctgaagctt tgcaaatgag
     3661 tgtgccggct tccgtaaaaa tacatatggc tataatttgc gttttaaggc gttttaaacg
     3721 ttctggtata taaaattata ccaaaacaac tttaaaacgc cttagatcta attttagagg
     3781 tcttatagaa cattttaggg ttgttagggc ttgccctgac cgcctgtaag gcgctttgag
     3841 aacaagataa gggttttata ctaagactgt cttaaaacgg cttaaacaaa cgctcagaac
     3901 ttttcaaagg agttctttat gaactgtttt taagcaaagg agcctttagg cgactgcgca
     3961 gtataatgtg agagcgtagc gatcacacat ttttagtgac cgtagggagc gagtttccca
     4021 gtttagaaaa attcgcgaac ttgtttgagg aaaaaagcag gagtttttta ggcgggaaat
     4081 tttgcctcct cttttataat ctctttttaa acctcttttt aaacctcttt accgtcggct
     4141 gtatgcttac tctcccaagg tgtgcagaat cttttggggg tctttttgtc tgtttttagg
     4201 ggtctttttg tctgttttta ggggtctttt tgtctgtttt tgggggtctt tttgtctgtt
     4261 tttaggggtc tttaattagg ggcttgaccc ctattagaaa gctctttata attttgttaa
     4321 gtagttaatc ttgaaggagg attttatggc aaatgaaatt gtgaaatacc accatgaatt
     4381 aaatacgatt cctttacgca aatttacgtc agtagaaatg aatttattct tctctatagt
     4441 atctagaatg cgtgacgtag gcgataaaaa agtacaattt acattcgaac aattaaaaga
     4501 tttaagcaat tataaagcaa ctgcaaatgt tcgattcata gatgatttag aaacaacgta
     4561 tgacaaatta atggatttac gttttggtag aagaagtgct gacggtttgc aacgtgaacg
     4621 atttgtttta tttaatcaat ttaaaatcga tggaaaagct gatattcctt ttgctgaaat
     4681 acaagtccat gagaaagcct tacccttact taataatctt gaagaatggg ttcgatattc
     4741 tctccaacaa ttcaatgaat tagaaagcag ttattccaaa accatgttta gattat
//
LOCUS       DAZKNV010000119         4729 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000119 DAZKNV010000000
VERSION     DAZKNV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.122"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            95..1054
                     /locus_tag="ACG8M1_002767"
     CDS             95..1054
                     /locus_tag="ACG8M1_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="HFQ0423416.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINF
                     LKEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPIS
                     CSVRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEF
                     GHIEGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFK
                     SITFDCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQ
                     VDQAFISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
     gene            complement(1487..2059)
                     /locus_tag="ACG8M1_002768"
     CDS             complement(1487..2059)
                     /locus_tag="ACG8M1_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0423417.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2075..2680)
                     /gene="fic"
                     /locus_tag="ACG8M1_002769"
     CDS             complement(2075..2680)
                     /gene="fic"
                     /locus_tag="ACG8M1_002769"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFQ0423418.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(2860..3597)
                     /locus_tag="ACG8M1_002770"
                     /pseudo
     CDS             complement(2860..3597)
                     /locus_tag="ACG8M1_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336528.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(4040..>4729)
                     /locus_tag="ACG8M1_002771"
     CDS             complement(4040..>4729)
                     /locus_tag="ACG8M1_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnsA endonuclease N-terminal domain-containing
                     protein"
                     /protein_id="HFQ0423419.1"
                     /translation="YQYSNLTLIAEIARYLNFSPLEVQRILTESQDGLEQILFWSNTY
                     KQVVYEILIPKIFEYKFKITKSQITEDNEVVLLKFPQGKNYYKFSGKPELVIMDSDKQ
                     LENYKTKSFHADTYVFDSKPERELFLQYLENDTVEEIFFTGMFTSKQGDFYIQYIDPE
                     ANSVRSYFPDFVVKKRDGSREIIEVKGDNKKDDPVVLAKKAATEEQAGQSGYSYRMIL
                     GSEIMNNNYEI"
BASE COUNT         1436 a          916 c          804 g         1573 t
ORIGIN      
        1 gccgattgta aaattaagct agacaaataa ataagccatt cgtgctacac tcaaaatgta
       61 attccgacta aagaaaacat aggagtgatc acgaatgacc tacacccatc ttaccacgga
      121 tgaactggtg atgatagagt cttactacca ccaaaacatc aaaattgtga aaattgctga
      181 gtacctgaaa cgatctcgaa caccgattta taacgtcatt aatttcttga aagaaggcca
      241 tacggccctc gaatactacc aacagtataa agaaaataag aaacggtgtg gcagacgaaa
      301 catcgtcttg ccaaagaaac aacagtccta cattaaagaa aaaattgccc aaggctggac
      361 gccagacgtt atcattgggc gtaaagagaa accaatcagc tgttccgtaa gaacccttta
      421 tcgccagttc aaggaaaagg tgttcgatga atcgactttg cccatgaagg gtaagcggaa
      481 accaaatgga catcaagaac gccgaggaaa acaggctttt aaacggaata tcgttgaaag
      541 agaaactgat tacccgacat ttaaagaaga gttcggccat atcgaaggcg ataccattgt
      601 aggcattcat cataagagtg ctgtcataac tttggtagaa cgtctatcga aaatcatcat
      661 caccttgaag cccgaggggc gcaaggcgat cgatattgag aatactctga accactggtt
      721 tggatcgatt cccagacatt tatttaaatc cattaccttt gattgtggga aagaattctc
      781 taattggaag gctttaagta accaacatga catcgctatt tatttcgctg atccagggac
      841 tccttcgcaa cgagcactga atgaaaattc caatggcttg ctgcgaaaag atggtctgcc
      901 aaaaaacatg gattttaatc aagtcgacca agcttttatc tcttcagtgg cgaataagag
      961 aaacaatatt ccacgaaagt ccttggatta tcaaacaccc ctggaagtat ttatgagtta
     1021 catgaatgaa gatattttgt ctagcttaat ttgacaaatc aaattattta aaactttgca
     1081 acagaacctt agcagcagtg ctgattttta tgatagttat ttggttctta aatgaaagat
     1141 ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca atagattatt
     1201 tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg aacgatatgt
     1261 gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc taatatagta
     1321 agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca cattttttga
     1381 gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag actcatatct
     1441 agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa ctttcttcaa
     1501 ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct tcaacttcct
     1561 tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt gtgattgttg
     1621 ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt tttccttctt
     1681 gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac gtccgtgtca
     1741 ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg atcgttacgt
     1801 tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga gcaaatcgat
     1861 caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc tgattgaatt
     1921 ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc ttctctacgc
     1981 cgttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt gagacacgtg
     2041 catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc gtatactcag
     2101 aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg cgatcgtcaa
     2161 ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt atgggacttc
     2221 gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca actttttgca
     2281 attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt ccttctcgaa
     2341 atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa gaagtttgtg
     2401 gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca aatcgaaaat
     2461 ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata tccgaaaata
     2521 gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca tttatttttc
     2581 cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc ttagccaact
     2641 caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc cttaacttta
     2701 tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt tatgtgtcaa
     2761 aaactattaa gtttctgacc ctctacaaaa ttcacaatag atataatcta ttgaaaattt
     2821 aaaagaagac aaaatagagt acagaaaatg ttttctgtac tctataaatg attctgatac
     2881 ttcattgaag tccatggctt taactaatcc atcacgacgt aataatccat ttgaatgttc
     2941 atttagagcg cgttgtgacg gggtgcctgg atccgcaaaa taaatatcaa tatcattttg
     3001 atttcccata gctttccaat ttgaaaattc tttcccacag tcaaacgtaa ttgatttaaa
     3061 cagatgttta ggaaccgttt gaaaccaatg attaattcga ttttcaatgt ccattgcctg
     3121 tctaccggct ggcttcaatg taataatcac ttttgacaaa cgttccacca atgtaataac
     3181 agcacttttg tgttttcgac cgacaatagt gtctccttca agatggccaa actcgttttc
     3241 aaattctgga tgctccttga tgcgctcatg tatactgcgc cgaaaagctt gtttcccacg
     3301 tttttcttgg tgtccatttg gttttcgttt gcctttcata ggcaaatcac gcacattaaa
     3361 tgcgccagtt tgaaacattc gatacagtgt acggactgaa caatcaagtt tcatttccga
     3421 gcggccgaca atcacatccg gtgtccaccc ttgaacaacc ctcttttgaa catattcttt
     3481 ttgttcctct ggtaaagcaa tcgagcgtct accgcagcgt tttttgtttt ctttgtattg
     3541 ttgatagtag ttcagtatcg tagcaccagt tttcaaaaat tgatacacgt tatgaatcgt
     3601 ttgtcacgca cgtcctaagc attgcgcagt tttggcaacg gattgattat ttttgaaata
     3661 agactctatg attaccagtt cgtctgttgt aagatgggtg taggtcattt gtactcactc
     3721 cttaataatt ctttggtcgg aactattttg agtgtagcac aaatgatctt tttagttgtc
     3781 tagcttaatt ttacaatcga cgaaaagaat actatgatga gattagtttg aaatttcatt
     3841 ttgatgagta gatattagga actgattgat agaacgaata agttatattg atattttgta
     3901 tttgcagtat ttgaaaaagt tgaagatgat aaggaaaata aagaaacaac aggaacagtc
     3961 taacttgact attcctgttg ttgaaaagat tatgattaat ttactacttt attttttata
     4021 gacatgctat ttacatactc tatatttcat agttgttatt cataatttca cttccaagta
     4081 tcatcctgta tgaataacca gattggcccg cttgttcttc tgttgctgct tttttagcta
     4141 ggacaacggg atcatctttt ttattatctc ctttaacctc gataatttcc cgacttccat
     4201 ctcttttctt gaccacaaaa tccggaaaat aactacgaac agagttggct tcgggatcga
     4261 tgtattggat gtagaagtct ccttgtttgc tggtaaacat tcctgtaaag aatatctctt
     4321 cgactgtatc attttctaga tattgtaaga aaagttcgcg ctcgggtttt gagtcaaaca
     4381 cataggtatc ggcgtggaag ctctttgttt tataattttc taattgctta tctgaatcca
     4441 ttataaccag ttctggtttg ccactaaatt tgtagtaatt ttttccttga gggaacttca
     4501 agagaacgac ctcgttgtct tctgtaattt gagatttagt tattttgaat ttatactcaa
     4561 atattttagg gattaatatc tcataaacta cttgtttata ggtatttgac cagaagagaa
     4621 tttgctctag tccatcttgc gattcagtta ggattctttg tacctctaga ggactaaagt
     4681 tcaagtatct ggcgatttcg gcgattaaag ttagattgga atattggta
//
LOCUS       DAZKNV010000120         4422 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000120 DAZKNV010000000
VERSION     DAZKNV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.123"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            690..1658
                     /locus_tag="ACG8M1_002772"
     CDS             690..1658
                     /locus_tag="ACG8M1_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0423420.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="ACG8M1_002773"
     CDS             1669..2484
                     /locus_tag="ACG8M1_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFQ0423421.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="ACG8M1_002774"
     CDS             2552..3262
                     /locus_tag="ACG8M1_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0423422.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4422
                     /locus_tag="ACG8M1_002775"
     CDS             3298..>4422
                     /locus_tag="ACG8M1_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFQ0423423.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKML
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         1486 a          662 c          922 g         1352 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgcacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaaa aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatgttatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt tttgatttca aggagtagat tttatttatg
     3301 aagcaagtat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatgct tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aa
//
LOCUS       DAZKNV010000121         4359 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000121 DAZKNV010000000
VERSION     DAZKNV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.125"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACG8M1_002776"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACG8M1_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFQ0423424.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="ACG8M1_002777"
     CDS             complement(2944..3378)
                     /locus_tag="ACG8M1_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423425.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..>4359)
                     /locus_tag="ACG8M1_002778"
     CDS             complement(3395..>4359)
                     /locus_tag="ACG8M1_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFQ0423426.1"
                     /translation="FGPFRANNIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLG
                     DIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLY
                     ENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLG
                     MDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQ
                     FIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNH
                     TISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT         1341 a          815 c          601 g         1602 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaata
//
LOCUS       DAZKNV010000122         4293 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000122 DAZKNV010000000
VERSION     DAZKNV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.126"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..790
                     /locus_tag="ACG8M1_002779"
     CDS             <1..790
                     /locus_tag="ACG8M1_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFQ0423427.1"
                     /translation="CGYSKTEPRHSFGPAIREQYLIHIVLEGEGYYSINDQKYFLKKG
                     QGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYYLKEIGVGKNHLTFKVENLNSFK
                     GLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSASYLNEGIITKKMNPFVRQTIEII
                     RENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIKEYISEIKISIANDLLSSTEYS
                     IQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLGLGIINGE"
     gene            887..3136
                     /locus_tag="ACG8M1_002780"
     CDS             887..3136
                     /locus_tag="ACG8M1_002780"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFQ0423428.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3139..>4293
                     /locus_tag="ACG8M1_002781"
     CDS             3139..>4293
                     /locus_tag="ACG8M1_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0423429.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1501 a          610 c          790 g         1392 t
ORIGIN      
        1 ttgtgggtat tcaaaaacag aacctagaca tagttttgga ccagctattc gagaacaata
       61 cttaatacac atagtgctag aaggtgaagg ctattattca attaatgatc aaaaatattt
      121 tctgaagaaa ggccaaggat ttgttatccc accaggagta tctacttttt atcaagcaga
      181 tgaaaaaaat ccgtggtcat atgtatggtt gggtttaagt ggcaatcttg tagaatacta
      241 tctaaaagaa attggtgttg gaaagaatca tcttaccttt aaagtcgaaa atttaaattc
      301 atttaaagga ttaatttttg aaactttatc gtatgatcag gacaatctag tcagtgaatt
      361 gtccagacaa aaacaagttt ataaattttt agaactcctc ttaaattcag ctagttatct
      421 gaacgaaggg ataattacta aaaagatgaa tccttttgtt cgtcaaacaa ttgaaataat
      481 acgtgagaat gcgtatcaaa aattatctgt taaagatatt gctgtcagtc tatcgataca
      541 cgaaaattat ttatcacgat tgtttaagaa tgatatggga atatcaataa aagagtatat
      601 tagtgaaatc aaaatttcta ttgcaaacga tctgttatca tcaactgaat attcaatcca
      661 gcaaatcagt gacaagatag gattctcaac agtacaatct ttttctaaag cctttaagaa
      721 agcaaatggt gtttcaccgg gagtatatcg aaaacgtaga ttaggtctag gaatcattaa
      781 tggtgaataa actaaacatt tgattttgat aaatattcgt tactttaaac gcttactatt
      841 tatgtgagcg ttttttataa tgcaataaag aaacggagga gagcttatgt ataaggataa
      901 tgaaatgaat attatttatc gatcagaaaa ccaacaattt catttgttta atcaggagat
      961 aagttacatt tttaagatat cggaagatgg taaattattg catttatatt atggtgagaa
     1021 cttaccagat aatgactata gtcatctaat tgagatgcat catcggccta tgacaaccta
     1081 tagaaatgaa aacgatttgc tatattcgtt agagcactta aaacaagaat ttcctgaata
     1141 tggtacaaca gattttagac atcctgctat ttcattacta cagaaaaatg gctctcgctt
     1201 atcagatttt gtctatcaag ggtacgaagt ggaagaagga aaacctaaac tagaaggttt
     1261 acctgctacc tatgttgata ataatgatga aagcaaaaca ttgaaagttt atattttaga
     1321 ttcagttaca aatgttcaag tagaattatt atatacaatt tatagagatt atcctgttat
     1381 tactcgtagc gcgcgagtta tgaataaagg aaaagatatt caaataatcg agaatattag
     1441 cagtttatca ttggatttac ccgatgcaaa ttatgaatgg caacaattat ctggtgcttg
     1501 gggtagagaa agaactatta agtcgcgtac tttacaacaa ggaattcaat caatcgaatc
     1561 tactcgaggt atttcaagcc atcagcataa cccatttgtt actttaaaaa gaaaaaatac
     1621 tgatgaaaat caaggagaag ctattggtgc agcactagtt tactcaggaa acttcttaat
     1681 tcaagcagaa gtagatacat gggatgttac tagactacaa gttggcatca atccatttgg
     1741 atttaattgg aaactcaatc caggagaaat atttacagca ccagaagcga ttctggttta
     1801 ttcaagtaag ggtttaaatg ccatgagtca aacttttcat caactattta gaaaacgctt
     1861 agctcgtggt aagtggcgag aaaaagaccg tcctgtctta attaataatt gggaagcaac
     1921 atattttgat tttgacgaag aaaagttggt aaatattgct aaaaaagcat ttgatgttgg
     1981 tattgaatta tttgtattag atgatggctg gtttggagaa agagaaaacg attgtgcagg
     2041 attaggagat tggcatgtaa atcctaaaag actacctaga ggaatcggca gcctttcaga
     2101 aaaaattcgt agttttggta tgaaatttgg tttatggttt gaacctgaaa tggtgaataa
     2161 ggatagtgag ttatatcgca cacatccgaa ttggattatt tctacaccta atcgaaaacc
     2221 taatcatggt aggaaccaat atgtattaaa ttttgggtta gatgaggttg ttgaaaatat
     2281 tttcgatcaa atgtgtaaaa tcattgatga atcaaactta gattacatta agtgggatat
     2341 gaatcgtcca ttgactgatg tatttgacag tcacttgtca gcagatcaac aaggagaagt
     2401 attccacaga tatgtactag gcgtatatcg cttatatgaa aaacttataa caaaatatcc
     2461 taacatacta tttgagtctt gttcatcagg tggtgggcgc tttgatcctg gaatgcttca
     2521 ctatgcacct caagcttggg ctagtgatga ttcagatgca attgaaaggt taaaaattca
     2581 atatggaact agtatgctgt atcctctttc gtctattggt gctcatgtat caattgttcc
     2641 aaatcatcaa acaaaccgta taacacctat aaaaactaga ggaaatgtag ctttttttgg
     2701 tgcatttgga tatgagcttg acttaaatga attaagtgaa ggcgatttga ggattgtaaa
     2761 agaacaaatt gccttttata aaaaatatag aaccataatt cataatggta ctttttatag
     2821 actattatca ccattcgatg atgataatca aaccgcgtgg atggttgtta gtcatgataa
     2881 gaaaacggct attgttgctc attataaaac attaaatgag gtaaatgctc cttaccgccg
     2941 actgaaatta aaagggttag ataatgacgg actttataat gtaggacaaa atagtttgcg
     3001 atctggaatg gaattgatga gagcaggact agtctgttca gatgcatcta gtggacaaat
     3061 aaatgatcag aatcgacgcc cagaaacatt tgattttgat tccaagattt gggttataac
     3121 acaggaggaa aagtagagat gaataaccaa aaaagcttac ttcaaaaagg agcaatctta
     3181 agtatttcac taatgttaac aagctctcaa gcaattaatg gtgttattcc acaaatgaaa
     3241 cagtctttgg ggatatcaca aagtcaaagt gaacttttag gaactgcacc aagtataact
     3301 gttattttgt ttatcttatt atctagttac tttgccaaaa gaataggaat gaaaaagaca
     3361 ataattttag gtttattatt agctggtata ggaggaatta ttccagtatt tacagctacc
     3421 ttccaaaccg ttcttattag tcgagtaata ttaggtgccg gtttaggagt atataattca
     3481 ttggctgtga catatatcag ctctttatac tctggcaata ctagagcaac gctattaggt
     3541 attagaaatt caatggaagc tttaggtcag acaatcctta tttttcttgc tggagtttta
     3601 gtgaacatta attggacggc ttcgttttta gtctatgcaa ttgcgtttcc tgtagctctc
     3661 ttattcgcgc taaaagttcc tgaaattaga gatgaaaata gtgacatacc tgaaaatcat
     3721 gtaaaagaaa agatgaatcc aatggttttt gccctagttc tatttgcaat cttactcgta
     3781 atgaatagta ttgctatttc tgtacgattt gcatcaattg caactgaaat taaaggggta
     3841 aactttaatg ctagtaacta tttagctcta atgcctatct taggaatact agcaggattt
     3901 atgtttggac caataaataa gtggatagga aaaggaaccc tatacttggg aattatattc
     3961 tttataattt caaatttgtt aattgctgtg tcaaacggta atatgacgtt cctgctaacg
     4021 ggtttatttt tatcaagtat aacaggatca tggtgcttcc catttatctt tagtaactta
     4081 gataaagtca ctacaaagaa tacaattaat tttgctactt cattgatttt tattggctgt
     4141 aatattggta attttatagc tcctattgct atgcaattag cacaatttct aacaagaagt
     4201 acaaatttga ctgctccatt ttttgtattc gcaggaatat ttattgtgat cctatttgta
     4261 acattttttg cgacaaataa aaaaaatact aga
//
LOCUS       DAZKNV010000123         4147 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000123 DAZKNV010000000
VERSION     DAZKNV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.128"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            52..1353
                     /locus_tag="ACG8M1_002782"
     CDS             52..1353
                     /locus_tag="ACG8M1_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0423430.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1380..1640
                     /locus_tag="ACG8M1_002783"
     CDS             1380..1640
                     /locus_tag="ACG8M1_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFQ0423431.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2639..3874)
                     /locus_tag="ACG8M1_002784"
     CDS             complement(2639..3874)
                     /locus_tag="ACG8M1_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0423432.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1196 a          670 c          861 g         1420 t
ORIGIN      
        1 gcgttgtcat gcaatgaatg gttcatattt tattgaaaag gagtggtttt agtggaaaag
       61 ctgatgaaat gggtcgaaga gaaacttgtc ccaccaatgg caaaaattgg tacacagcgt
      121 catttattag caattcgtaa tggggttgtt tcaacattgt cattgatttt gattgggaca
      181 ttttttatgg tctttatcaa tttaccgttt cctggatgga atgaatttat tgccccttat
      241 tcggcaacga ttgttttacc ttttaggatg acgatgggat tgatggctat ttatgcaact
      301 tttgttatgg gttcggatct agctaaatca tatggattag atagtgtgac aggtggtata
      361 ttatctttag gaacgttctt tatgttacaa gttcctgtaa acgttttaac tcctgaaaag
      421 gcacctcttg gctgggtctt acctatgagt tctttgggag catctgggat gtttgcgggg
      481 atcttatcta tgatttttgc agtggaagta tatcgtttct ttaaaaatcg aaatattact
      541 atcaaaatgc cagaacaagt gccacctgct gttgcccgta gttttgaggc attgattcca
      601 ggtgcagtca ttttaacaat tacttggctg attcgaagcg tcgcgggctt tgatgtaaac
      661 gctaccttat tatcgttatt cgagccttta accaatattt tagggaataa tttgcttggt
      721 gttttactac caatgttttt gatccatttg ttgtggtcat ttggtatcca tggcatgagt
      781 attgtagggg ctgttgttcg tccaatgtgg ctgatcatgt tggatgagaa tgcaaaggca
      841 ttggcagatg gtacagctgc cacccaatta ccctatatcg ctcctgaaca gttttatcaa
      901 tggacggtaa caattggtgg tgcaggagca acgatcgtgg tatctgtttt gtttatattc
      961 ttctgtaaat caaaattctt gaaagaggtt ggtcgttttt ctattattcc tggtatcttc
     1021 aatatcaatg agcccatgat ttttggagct cctatgatgt tgaatcctta catgttcatc
     1081 ccgttcaact tagttccttt agttttgact attatcagtt attttgcagt caaattagaa
     1141 atggtcaata gatttactgt tttgccaact tggacattac cagctccaat cggcggttat
     1201 ctttcagcag gaaatgactg gcgtgttgtt atcttgatca tgatcaacac attgatagca
     1261 tttattatct attatccatt tgtaaaagct tatgataaaa agatgctgtc agatgaacaa
     1321 agtcgtggag aaaacgaagt ccaaactgtc taagtttggt ttttagaagg tgggaaacaa
     1381 tgtattggct gattttattt tttgttttta tctttttatt aacggctagt caccttatat
     1441 tgaatatgct agctacatat catattcaaa tcaatcgatg gatttgggca ctggcatcat
     1501 ttttgatcgt gattcttcca aagatcattg taccgcatat gaatgttttg ttttcatggg
     1561 ggacatatgt actttgtgga atttttgcta tcaattttat gatcgagcag catagatggt
     1621 ttgtcacatc gaagctttaa atgttctaaa agtggttgtg acagaagtgg ttagcttcaa
     1681 gaaataagaa gaaatttacg aaaattgctt cttaaatttt tgtgaaatgt tggcttattt
     1741 ttcgtttggt tgaacttatt accgcagatg caagcttttg accaccgttt attcggaata
     1801 tgggactgtg acaaggcttt tgtcacagcc cttttttaca taaagattat tattgtttta
     1861 actgttttgg cagaaagaag gaggcaaaaa tgaaaatttt atcagcaatg gattaagaat
     1921 tagtcgatct actaccaaag tgatcaaggc aaatatagat ttgggagctt acaaccatat
     1981 agtaggggct gcagtatggt gtatgaatgg taatatgtat gatgagagtg tttattcaaa
     2041 tcatgaaacg tgtatagaaa taattgcgct gggaatagca atcagtcatg gtgaacgtga
     2101 cttttagttt atcgttgctg acgacataga acattctgac atgatctact cagcatgtgg
     2161 ggattgctgg cagtttatat aggagtatgc atcggattgc gagatcattg tctcaacaga
     2221 agagggaggt tgattatcaa agataaagtg gtaaatccta catttgattt agtaattgtt
     2281 gaagggacta gcagcacaaa tctctacaaa gcgatgcttc tagatctata tgacacattt
     2341 taagaaaatg tatttgccta attattatgg tctttctttt gaagaaacgt tgagatgatc
     2401 caaccagaga aaggtgtcaa agaatttgac taagaataaa tggcagacgc tacctatgct
     2461 catttggatt gcgtcagatc ttttatttta aggatgattt tgtgtttttt agacaccgta
     2521 atttaagtaa ctctaacttt tcaatccact atttactttt tttgtatttt cactgtctgg
     2581 gtctcgaata gcgaaattac tgatgagtct ctattaaaaa agctttttct acttgaaact
     2641 atattgggtg gttgctcagg aaggtttcga tttcttgaat tgcttgttgt ggaccattta
     2701 ttggaaaaac ggcttgcagc gtgcgtgcct gctgacgaat cttgggtgaa gaaacttcgc
     2761 gcagagcaat ctgcagtttt ctttcagtca ctggttttgt gagggcgatt gcgtttccgt
     2821 attttacaca atagtcaata ttacagcttt gctcaaattg catccccaca ccgataaacg
     2881 gtttgccgga ttcacaggca gtttggacgg tcccttcccc gccgtggata aaagaaaaat
     2941 caatgaattc atgcaaaaga tgactagaca gatattctgt tattaaaaga tcttctgagt
     3001 cagattgaat gtcatcaagc agatagtcaa taggtgcaat aaccgctaga tccggttgtt
     3061 tttgtaagaa gaacaaaatt ttgcgtaaca tacgcggatt gcctgaacta cccattgcga
     3121 aatagataat acgttttctt tcttgttgct ttcgctgtat aaaagttagc acttcttcag
     3181 gcaaggaagt actgagctta gcaaaaattg gaccaacgat tcgataattt tccggcagct
     3241 gttcttcttc caaaaatagt ttaggcgttg tgatgagatt tagatcagca tccatcattt
     3301 gtaaacttgt ttttggtaaa ggaagcattt ctttttgtgc agcgtgtttg aaggcattgg
     3361 ggatccatcg ggtatttact atacgctttt ttgtccagtg ccaaagggga ttgcttaaag
     3421 ggccgaagaa acgtaactcg tggggcatca gcgcatgctc tgattgaaaa aaaggttcac
     3481 tcaaagcata gggtttaaca tatactaaag gaatcttttt attgcgggcc gataaaaaaa
     3541 ttgtcacatt cgaacctgtc acaatcagtc gaggctcaaa cttagcaatc agactctgtt
     3601 cactagtgat acgagaggca accatttctt tggtaaaagg gtttttaagt gtacgcaact
     3661 ggtcaaattt tatgatttgt tcttcttgtt ttttcgtaag gatcggcgct agtaaatgat
     3721 actcaaagcc actttctgtg atcaaaggag caaaagtttt agaaaagcca aagaatacac
     3781 agtaataacg gtctttcata gctttggcaa cctcaatcat tcgtgttgtc tcagctaaat
     3841 tgaatactgc aggagcaaaa agaattgtct tcatgaaatc ctccttattg gaatgagtct
     3901 atcccttcgt ttcttactag tatactaaaa aacacagcgt tcgagtagcc tatgtatatt
     3961 ttgaatatta aactgtctct cgctgttttc acaacttcta aatttaaatt ttgtaatcaa
     4021 gttgaaactc caattttcaa aaaaacacgc aacaattttt tgatcgattt atatgttgtg
     4081 ccagataaat acgagaagtt gtgtcattaa aaataaacat gagaacataa aaaataaaat
     4141 aattata
//
LOCUS       DAZKNV010000124         3836 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000124 DAZKNV010000000
VERSION     DAZKNV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3836
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.129"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1086
                     /locus_tag="ACG8M1_002785"
     CDS             <1..1086
                     /locus_tag="ACG8M1_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0423433.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1304..2446)
                     /locus_tag="ACG8M1_002786"
     CDS             complement(1304..2446)
                     /locus_tag="ACG8M1_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0423434.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2451..2636)
                     /locus_tag="ACG8M1_002787"
     CDS             complement(2451..2636)
                     /locus_tag="ACG8M1_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFQ0423435.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2990..3235)
                     /locus_tag="ACG8M1_002788"
     CDS             complement(2990..3235)
                     /locus_tag="ACG8M1_002788"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423436.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3229..3630)
                     /locus_tag="ACG8M1_002789"
     CDS             complement(3229..3630)
                     /locus_tag="ACG8M1_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0423437.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
BASE COUNT         1258 a          700 c          596 g         1282 t
ORIGIN      
        1 gatatcaatg atgatggctc aagaaaaaaa gtggagaaag ttggcggaga cacccgacca
       61 gaggccgaag ctgctttacg aaaagtttta tcagatattg acgaaacagg acaatacttt
      121 ttaggtacgg atactcgagt aaaacaatac cttgattttt ggatggagga atacgttaaa
      181 ctaaatctaa aatacaatac ctatgaaaac taccgattta ccatcaaaaa tcatataaac
      241 ggttatttag gaaagaaaaa acttacggat ctctcccctg ctcttttaca aaatttcatc
      301 aatgctgaat ttaaaaaggg ttactcgaag aaaacaatga ctattactca ctctgtcctt
      361 aagaatgcgc tgaatatggc ggtttatcct tggggattaa tcaagcaaaa tcctatgctg
      421 tatgtaaaaa taccaaaata tgaagcacga ccaacgacta aaaaagatct aaaaatcatt
      481 tctcttgagg actttgatca tatgctagaa attactcctg aaggacatcc tttctatatt
      541 cctttgaata ttggatttta tacgggaatg cgcgttggcg aagtttgtgg tctgacgtgg
      601 gatgatgtcg atttttcaaa tggaacaatt actgtagaga aacaaatggt aaagaatgac
      661 ggcgcatggg tatatggtac gccaaagaca agcagttcca atcgaacgat ttttattgga
      721 caaaccttgc tagcaattct gaaaaaacat aagaaacaac aattagaaaa tcgaatgaag
      781 tatggaaagc tctacattga ttcaaatgca gtatgtacga aggaagacgg tgagctagtt
      841 acgccaagtg tagtgaaatg gaatactagg aggatatcga atgcactctc cctctctttt
      901 aacttccatt ctctcagaca tactcatgct acacttcttc tcgaaaatgg cgcaaaaatg
      961 aaagaaatct ctgaacgatt gggccacagc agaatttcaa ttacgatgga tacttactcg
     1021 catgtaacag ataagatgag aaatgaaacg gtcgatatca tggaaaatct tagaaagaat
     1081 tcttgatttt tgccaccgaa aaaaaccacc ggtggcaaac cggtggcaaa tccatgtaaa
     1141 catggtttat tttttacact gttttcaaac aaacccttgc tatttcttcg gttcgtcctc
     1201 gtccattttc gataccgaca gctagcttat aacccaaggt atatcaacat aaaaaaataa
     1261 aaataggcta tgacagcagc gtgacagcaa aaaagatgga aagttaaata tcaaacctcg
     1321 taatttcatt tgcgagtgct tgatttgttt ctggatataa gtgtccatat ttgtccaaag
     1381 tagttttaat agaggcatga cctagacgct tagatattgc atagatattt ttattatgtt
     1441 caattaaaaa ggcaacatgc gagtgtctta atccatgcat atgaattggt tttactcctg
     1501 caatttcagc tagttttttt attctgctta aaatagttct tggagatggc ggtaatccat
     1561 caaaagaaaa aaccaattct atatttttcc caattgattg ttgagttttt ttccatgttt
     1621 ttaaatcttc aacggtttgt ctgtctaacg aaattatccg aatacttgat gtattttttg
     1681 tttcagcaaa ttcataatct tgtcttgtac ggatgtaaat tgacttattt acgctacatc
     1741 tgccatttat taagtcaaag tctttccatt gtaacgctaa gagctcctca ctccttacac
     1801 ctgtaacaaa aataaaacgc atcaaacgtt tataaaattc ttcataaaaa tccccgtgat
     1861 aaacactatt atatactttc ttaaattcat caactgtcca aaattctact tgaggacgct
     1921 gagtttttat tttacctata gtatctacag gattttcttc aataatttca agtacaattg
     1981 cccttttaaa aactactctc aacttattga atatctgttt aatataattt ggtgataatg
     2041 gttgctcaat gccctttttt acaacatgga ttttcgataa aaactgttga aattcctgta
     2101 tatgaattgg tcgaatcttt acaacctgca tttctccaaa aaaatccaat gcacgttgta
     2161 aaatatgatc tgttttcata tatgtttttt ctacagttcc caacttatac caaggaaaaa
     2221 aatactctcg ataaaaatca tgaaacgtta ttccttgcag ataaattcct tgtgaatcag
     2281 aaaaactttg ttttaactct tcgagtcccc ttctagcttc tccttgagtt ttgaagcctc
     2341 ttctggtcac ttgaattctt tttccaaagc gatcttgtcc taaagttgca gaaaaaaacc
     2401 aagtgcctct ttttctgtct ttataaacat tcgcaatttt cctcatttta ctattcctcc
     2461 caagaaatat ggagaacttc ttctaaaatt gaaataggaa ttctttttat ttttgaatta
     2521 cgataaaaaa agtatccttt ctcaactaaa agttctttac attccttgaa gattttatta
     2581 gcatagtact gagaaaaacc tagattaatc aaatcttttc gagtagctgt tttcattata
     2641 gcaccttcct tacttttttt catttatttc tatcagctgc ttttgtcaaa agcacatagg
     2701 aatttcacct ctccccaagt ttacggcgag ccttacggaa gtatcattat cccaacttta
     2761 aatcatcgct ttttattgac tataaaaatt attttagaat atttatcgct ccttctttac
     2821 agcaagaaat catggcgcaa ctaaaatatg ctccttaaag tgttaacgta ctgatagaat
     2881 ctatttaatt ttcaatgaac aataggtttt ctacctaaaa gaatctacta attccttaac
     2941 tattagaaga ttcttttaaa cagaaaaagt ggaaagggga tttttttaat tagttaattt
     3001 taaattttaa gatcgcttct attaatttaa tttctagctg acttatcata tattcatcta
     3061 cataggtaac gaattgacct acctcgttaa atccatttgt caaacataac ttagccatat
     3121 aagaatgata atgtttgagt atcatcttga tcgaaattgg atctccttct agagcagata
     3181 agataatgga tagtggaact aataggtact gccgcttttt agatttatct accataggtc
     3241 ataccccatt ttcaattgtt caactgcctt ctttcgttga taccagatac cacttgtgct
     3301 catattgaga attttaccga tttcagcatc attaaaacct gcaaaataat aaagtaggat
     3361 aatctttctt cttatctccg ataactgatc aattgctgct gataactttt gatctgaaat
     3421 taatatttcc attccaaata agaaatagac atcttgttca tcaaaatgag tttgggaata
     3481 cctgccttca tttgaatctg ccaatggttc ctcattatcc tttatgttag cgtttcgttt
     3541 tcgaatagac ttagcttcgt ttcgtaatac ttttttacag taggcatcaa attggtgttg
     3601 tatagatatg tcattgtaat gttgttgcat gataatatgc tcctttttcc ccctttccac
     3661 taatacaacg taagcgcccc atagaacagt accttactaa caaatgcacc tcaagatata
     3721 cttgagctat caagaagtct ggaggttttc tatgtataaa ttaaatgaga ttgttcctgt
     3781 ccaattagga aacgaaaaga gtgcaccaga aaaaggtaaa cccgcggctg ccaagt
//
LOCUS       DAZKNV010000125         3789 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000125 DAZKNV010000000
VERSION     DAZKNV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.130"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(147..533)
                     /locus_tag="ACG8M1_002790"
     CDS             complement(147..533)
                     /locus_tag="ACG8M1_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0423438.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(801..950)
                     /locus_tag="ACG8M1_002791"
     CDS             complement(801..950)
                     /locus_tag="ACG8M1_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423439.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            1412..1624
                     /locus_tag="ACG8M1_002792"
     CDS             1412..1624
                     /locus_tag="ACG8M1_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423440.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(1902..3701)
                     /locus_tag="ACG8M1_002793"
     CDS             complement(1902..3701)
                     /locus_tag="ACG8M1_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFQ0423441.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         1296 a          675 c          652 g         1166 t
ORIGIN      
        1 cgattgattg ccttgctctt tagtttgttt taggacttta agaacagtga ggctgacttc
       61 gaaggttaat tctgtttttt tgttttctag aatcagtaag caaaaaagca ctcacttcga
      121 gtgctttttt gcgatatatt cttagcttaa gataggccta atttttcttt tacagatgag
      181 ggtaccttat cgctggtaat tacttttttc tctatgatcc gcttttcgct tgctttcaac
      241 tgcaagatcg ttccttcggt gtaagcagaa ccattggcag agtcaccaga agtaatgaca
      301 tcgaaatcta actgtctttt ttcaccgttt tcagcataag catctacgtt gtatttaaaa
      361 cctcttccaa ttacttcccc attatctgct ttgatatcag tttctgcagg cattggagct
      421 ttgactaccg cataataatc tttacctaca taagtagact gatagtagtc ccaacctttc
      481 catcctataa aagcaatcaa tatgataacg atcaacccta aaattttttt catgaaagat
      541 ctcctttttt atttttatta tattaaatat tatacagata ataacggaat attatcatcg
      601 aaacagctaa caaaattgtc ataaaaaacg agatggttga tattagaact tgtgtttttg
      661 tttaggtcta gagataaaga gagacaattt ccaaatatat gtaatgaata caaaaagacg
      721 tttgtcgcgg attaccgtta caaacgtctt ttattgattt tccgagatct catcagtcgc
      781 catttggaat ggttcactcc ttatctagat tcgtttaatg ctcggactgc ttgttcgatt
      841 gtaataccaa acgcaacgtt attttcgttt tgtgcatcaa tcgccataaa acggttagaa
      901 gttgtatcaa aagctacgcg gtattgcata tttgtttttg taaacgtcat aaaattcatc
      961 tcctttgtaa tgtaatttag ttcttgaaag tttcctttaa actttcgaac ttataccaag
     1021 tttagcatcg tacgtttttt gatgcaatta aaaagcattt atcattttcc ttatttattt
     1081 tttcttaaat ggtttagcta ttttctttta atccgataag tagcccaatc atcaaggtta
     1141 caaatactat tgcttgaata taaatcatat gctcacctct ttataaataa cttagcaata
     1201 taaagaaaaa aacgcacgaa caacatagga atataaacaa acgtttttgt cacaacgtct
     1261 aagatcgtgt taaaaaatag ttatctaaaa agcagaaaga tactcaaaat aaaaaataaa
     1321 aaaatgaata aaaacgtttt caaatacaag gtaatttgtt attataaaat aaagaaaaaa
     1381 caaaataaaa ataaagaaaa gagggaatga aatggtaaaa gcagaagtag gaagatctta
     1441 tatatgcaaa ccgatcggag tatctcatga actaatcggc tgtattgaac gtacatatat
     1501 caacacggct gtcgtgtatg ttgaaagtta tgaccaacga gactatcaac ttatcaatga
     1561 aagcaagtat cgcatgctcg taaaattctg tgatattagc gcacctactg aattggtttc
     1621 ttaaacagta tttttgagaa ttcgcaagaa ctcccttata atataaataa agacagaagg
     1681 gagcgagaag atatgccaaa aagaaaaagt tcagggaaaa tgggaattat tcttgcagtg
     1741 atctctgcaa ttcctgctat tttagctatt gttcgtgcga tgaaggaatc aagagaaagt
     1801 taagcacaca ttatgagcgt caaacaaaaa acgcatatac ctgcggtggc aggttatgcg
     1861 ttttttgttg tataaagact tttttcatta acgatttttg attagccgac tcccaaaaca
     1921 aaatttagca gtttatctga ataagtgatt tcttcatctg tttgtttcac actttcattt
     1981 agtagtccca tctcatcggt tatgatacca tccacaccat aaaacatcat gcgactcatg
     2041 gcatctgaat cgttgattgt ccatacatat acttcttttc cgtcttggtg ggcagaatta
     2101 atgaagttac ggttgatcgt actatattcc attgtcagaa aatcagcagg cgtcacaggg
     2161 ggcccaacaa tattgaaagg taagatgtag cccacataaa agtttggttc tgcttctttt
     2221 aaatctgaaa cggtttggta cgtcaaactt tgcaaaatat gatggttctc taagataact
     2281 ttgcggtatt tatggacaaa tcgttcgaca aggtcatccg aatctttttt agaggtcttg
     2341 atctcaataa gtaatttttg gtttagctta tgtgcttttt ccaaataaga atcaaaagaa
     2401 caaacagggg cttgcactcc gttttcagta actgtaagat ttgtcaattc tttcaatgta
     2461 agatcctgtg gtgttccatt tacccctgtt aagtgacgaa gatttgcatc atgcatcact
     2521 acgaaatgac catcttttgt ttcctgaaca tccatctcta cataatcagg atgatagtct
     2581 ctgcttgttt tttcaagtgc ttctaaagta ttttgcgccc cattttgggt actcacacct
     2641 ctgtgagaga cagtcactgg ttttgtctga acagctgaag tcagataatc catattgtaa
     2701 agacagacgc caataccgaa aaaaactgca aaaagagtca aaccagtgtt tttcagcgca
     2761 gagaaacgca agttgggggc ttgtgggata aaccacttag ggatctcagg caagaagcct
     2821 tcgtcatcca tgaaatcaac aatgatataa aaaatcccta cggtagacat cacgatattg
     2881 aataataaaa tcccttgtaa aagcgtcata gcaaacacag cgctgatcaa tgcatagtct
     2941 gggaaaaatt gttcaaccat actttgtgcc aaaataacaa cgatatatcc taaagaagaa
     3001 aggagtaaaa tcgtaccgcc aatcacaata aattggcccg tgatggccaa aagacgcgat
     3061 ttggtcaatg accagctttc ccgaatggct gctcgaaaag aacgatctcg tagaatcatt
     3121 tccggtaaag caaaaatcag tcgaatccca atatagccaa ggaaaatata aacgagtaaa
     3181 aaggaactga cgatgatcca acgattagca aaaataaaat ccataatgaa agcggggatt
     3241 tttatttttg acagtagatc agaattaaaa cttaatccgc tgatcggtag aatcaataaa
     3301 aaataagcaa ggaaaaacaa aaaagtaatg ggtctcactt tcttcagctg aagtatcgtc
     3361 aagtgtaaga gttgcttcaa agagattggt tctttctttt taataaaaaa aacactcatc
     3421 aaaagaaaag taaattcgaa ataaactaac agtaaaatcg tcatcaaaac tacgattaac
     3481 gagagtagaa ccccaggatg ttgagaaaaa attgaaggaa tattgtcata agacaaatag
     3541 tcaattgccc ctcggtgtaa aataaaacgg gtcgtactgc tcaataaggg taaacaaata
     3601 aataaaataa agccatgcat cagcaagaca tcacggaaat aagcttgtgt tccttttaaa
     3661 aagtcccaag cattacctaa gctacgtttc aaataattca tcctatcacc tgctcttcac
     3721 attgtagcgc aaatctaatg aaaaaggaaa gggtgcagtg tgttttgcag accctttccc
     3781 agatttaac
//
LOCUS       DAZKNV010000126         3588 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000126 DAZKNV010000000
VERSION     DAZKNV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.131"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..296)
                     /locus_tag="ACG8M1_002794"
     CDS             complement(<1..296)
                     /locus_tag="ACG8M1_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423442.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILL"
     gene            complement(594..1487)
                     /gene="sgrA"
                     /locus_tag="ACG8M1_002795"
     CDS             complement(594..1487)
                     /gene="sgrA"
                     /locus_tag="ACG8M1_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFQ0423443.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTGKVNNELDLVPII
                     PTKEQKRNAGSNLKSVLKQPDFVSRGIDHQEKAKETDNRKSDLPETGSRTLNKLITWM
                     GVLLILIVGASYFRSLFHRVK"
     gene            complement(1683..2522)
                     /locus_tag="ACG8M1_002796"
     CDS             complement(1683..2522)
                     /locus_tag="ACG8M1_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFQ0423444.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNRTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            2707..3588
                     /locus_tag="ACG8M1_002797"
                     /pseudo
     CDS             2707..3588
                     /locus_tag="ACG8M1_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
BASE COUNT         1223 a          721 c          527 g         1117 t
ORIGIN      
        1 agtaaaatat aaccaatcgt tccctctaaa agtatagaat aaactttact cagtaaaaac
       61 tgagaagaaa actcgacttt tatcatcttg ttttctgaaa gaaaagataa tttatattct
      121 ggataccttt cgcaaaacga ttctgcttgt tgaatcaccg aattcatctt agccagggtg
      181 tagtttagat ctaaagcgat atccttcacc acatataatt tctcgtctct ttcataacaa
      241 tagttcaaaa attgatatac ttgcctttca ttgatatcaa taaattcttc aaacaaagta
      301 catactcctt tttatctatt atttagactt attccgacag ctacatgaat aacgtacaaa
      361 tagattcgtt actgattttt cagagatact accatgcgca gtgtgcattg tcaattattc
      421 ttgctcttat tttccatttg tgttcctgtt atttcctgtt tctcaaatat gttagtaaac
      481 aaaaatagat ctggcaaagc tacaacttcg ccaggcaata cagcactctc gaatgaaata
      541 ttcactcaaa aatctatcgt tttattcaat tttagatctg ttgcttttat tctttatttc
      601 actcgatgga agagagaacg aaaatagctt gctcctacaa tcaaaatgag taacacaccc
      661 atccatgtaa ttagcttgtt caaggttcta ctaccagttt ctggtaaatc gctttttcta
      721 ttatctgttt ctttcgcttt ttcttgatga tcaattccac gagaaacaaa atcaggctgt
      781 tttagcacac tttttaggtt gctccctgca tttctctttt gttccttagt tggtatgata
      841 ggtaccaaat caagttcatt atttactttt cctgtgctgc tttcgctgct cgtgcttcct
      901 gtgctacttt cactactcgt actctccgta ctgctttcgc tgctcgtgtt ttctgtgcta
      961 ctttcactgc tcgtactctc tgtactgctt tcaccgctcg tgttttctgt actgctttca
     1021 ctacttgtgc tatccgtact gcttggcggt ccaacaactg tccaactgct tggtttcaaa
     1081 ttctccgtga tcgtcatctg tccatcataa aaaacaatca aatcaacttt atctttactc
     1141 ttgatctcat caatcgatag ttctgcagaa atcattattg tatactcaat accagcggtc
     1201 cattgtacgt cttttaaata aacttcccca ataacttttt ctgaacttcc attaccatcc
     1261 caaccatatg ttagaacagc atgtacatca ctagcattca cgcttttgtt tggtttgact
     1321 ggaatagtaa tgacttgttg tgtcatgtca taaacaatcc gatcagtttt cacagtaaat
     1381 gaaagattct catttgcccg ttcatttgca gaagtactga ttccaatcat tgctgcaatt
     1441 atactcagcc caagaataac aaataatacg gtcgctgttt tcttcatttc tatcactctc
     1501 catataatta ccttctattt gataaaggaa ttatataaaa tgaaaatgat gagaacacga
     1561 cagtcagttg tgaaaatcta acaaaagatg tcgtgtattc gcttgaattt gtttactttt
     1621 tcgtttaatc aatgacagac ttaaaaaagc aagaccgata tcagccttgc tttcttcatc
     1681 ttttattgat aaacagcagt gtatttcttc atccgctttg ttttatatgc atagagtaac
     1741 aaaccaacaa tcaagactaa caagaataat gtagttgata tagatgcttc agccccaaag
     1801 tttcccccag taattattgt attttgcgat tggatcagag tggagaaaaa accttgttct
     1861 tgcgttccgc tgactggtat acccaaaata gctccttgtg tccgattcca agtaatatga
     1921 gcaccaatag ccgtaaataa acttcctgta ctgtagataa gtgcgctgaa aaagcaacct
     1981 gctaaaaaga tattgaaaac tgccagaaat gtcatgttag gattcaatcc gtgcaaaaga
     2041 gcaaataatg cagcagatcc aatcattgct attaacggac caaatctaag catctgatgc
     2101 tgaaaaaagc cacggaataa aagctcttct gatgccccca ctgcaataaa taaaataaaa
     2161 ctcgttatca gcggcacaat gtttgcgttt cctgaatcta accgatacgc ccccgtcaaa
     2221 tataatggac tagtaataag cagaaacact ccaattccaa caacgagacc tcccgctaaa
     2281 tacccccagt cttttcctcg aacagaaaca ccataatctt ctattctttt tccttcgacc
     2341 ttactagcaa gaaataaagc tagtaaaaaa acagctaaat gtccgaccgt accggcaatt
     2401 gctccaatcc attcactatt tccaataaac atatccgcaa gtgcattatt gacaagaatt
     2461 cctaaaacaa aaccaactaa gactattaaa acagatccaa tcaaccgaat aatcctgatc
     2521 atctttcatc cctcctttat attaagttta acaacccttt tctttcttgt ctcgtgaaaa
     2581 ctatgtaaat gttctccatc atagagagaa tagattttta cgaactaaga atatctacag
     2641 caaccttacg aaaatgaaag actgtctccc taattcttct gttagactgt ttttaataag
     2701 gaaaggatgg gaaatttttt gaaaaaacaa ctactaatta tgtgcctttc agcatgtgca
     2761 attttactat tctcaggttg tagcaagtcc aatgaaacga ttgcaacgtt taaaggtgga
     2821 acacttacag ttcaggattt ttatgataac ccaaaagtta aatcaaataa tcaaacacta
     2881 ttaaaaaaaa tgattgtctt caaagcattt gatgatgtat acggaaaaga gatttcttca
     2941 aaggaagtaa caaaagaata taatgaacaa atcaaaaaac tcggtccaaa ctacaaggaa
     3001 caattaaaag cagttggcca aacagaagag acatataaga aactctttaa acagatgctg
     3061 gctttccaat acggtttgaa agccaatgta aaattaacag ataaagatct agacactgct
     3121 tggaaagaat tctatccaga agttagtaca cagatcattc tattttcgac taaagaagga
     3181 gcagataaag caaaaaaaga agcaaatgaa ggagaaaatt tctccaagct tgttcaagct
     3241 tatggaaaaa ataaaacatt aaaggaaact gatggaaaaa tgaattttga ttcaaccaat
     3301 ccagagattc attcctactg aagtaaaaaa agcagcattt aaactaaaaa acggggaagt
     3361 ttctgatatc attcctgtaa cagatccaac gacttatcag caaagctatt atctagtaaa
     3421 aatggtaaaa aaacaggata aaggttctaa taaagacaaa tacaaatctg agctagaaaa
     3481 aattgctacc gaagcaaaaa ctcttgatac ggaattcatg gataaaacaa tccgtaaagt
     3541 gatgaaaaaa gacaatgtaa ctattaaaga tccttatgta aaaaatat
//
LOCUS       DAZKNV010000127         3391 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000127 DAZKNV010000000
VERSION     DAZKNV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.132"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            140..1180
                     /locus_tag="ACG8M1_002798"
     CDS             140..1180
                     /locus_tag="ACG8M1_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0423445.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2004..2336
                     /gene="traE"
                     /locus_tag="ACG8M1_002799"
     CDS             2004..2336
                     /gene="traE"
                     /locus_tag="ACG8M1_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFQ0423446.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            2955..3296
                     /locus_tag="ACG8M1_002800"
     CDS             2955..3296
                     /locus_tag="ACG8M1_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFQ0423447.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1260 a          459 c          642 g         1030 t
ORIGIN      
        1 tcattttatt tctgatttta ggtagtattt aattaaaaaa cagttttaat gcgtttgcat
       61 tttttattta tctttgctat tttcgaaaag agtaggtaat tttacataaa taaaacaacg
      121 tgaaagtaga ggatctacaa tgactgattt taaatttttt aaggcggata gagtttacaa
      181 cgaattattt tatcaatttc caaaagtctt tattgtttct gacgaataca aaaaaatgaa
      241 agattcaact aagattgcct atatgctttt aaaagcaaga ttagagatcg caatcagcaa
      301 acggcaaatc gatgaagaag gtaatgttta ttttacttat acgacaaatg aactatgtag
      361 agtattaaac tgccaaaaac aaaaagcgat agcaatcaaa aaagagttgg aatcctttgg
      421 tttattatta caaaagcaga tgggatttaa caaacagtta gggaaaaata atcctaatag
      481 actatatcta gcagaattaa aagtctcaga aaatgatatc tacttactcg aaaaatttga
      541 tagagagaat agggaaaacg ttgataaatc agagggtatg aaaatcatac ccaccctcga
      601 cgaaaaatca gacgctgaat cccttggggc tcaagagggt atgaaaatca taccgtgcca
      661 aaacgttgat aaatcagagg gtatgaaaat cataccagaa cttaataata atatattaga
      721 cactaataga cacaatatag acactgaaaa agaccgccta caagatcaat tgttgttaga
      781 caattttgag acaattatga caaacgacag cattgctacg tttgtccctg aacgagtatt
      841 aaatttgata aaaacatttt cttcaagtta cagtgaagct caaaaaaccg tccagactat
      901 tcataatgca aagaaaaaag ctgaaataga aagtgatatt tcgatagttt ttgaagaact
      961 cgatagttat tatgtcaatg cagaacaaga attatacacg acactgttaa aagcctatca
     1021 aaaattaaaa accgaaaaag tcgaaaatat ccagaacctg atttttgtct atgtaaaaaa
     1081 ttggtttatc gaaaaaccaa tagctgctaa agtatcaagt gaaaaacgtt tgaattatgc
     1141 aagctcccca agcactatta cgaaagactg gttagagtga aactttactg acaaagtgat
     1201 tgttgcttca tggagtaaca ttaaaattaa aaatttttta ttattctaat tatattacga
     1261 atattacaaa ataatagcta ttttaataga atttataagt taaaatatta tgataaaaat
     1321 cacaaacgta gccttttacg tcataagtgt taaaagaaat aattaatttc aaatatagaa
     1381 aagggaacgt atgtttgcat actccttttt tttgagttat aataatacgc gaagagagat
     1441 aatttcatta tttaaacaag ctaaaaatct tgatattact tcttttcagg caatacgaat
     1501 attattcgct tacatttttt gtataaattt aattgtctgc tatgcttgtg atgaattgat
     1561 tttcgttttg cacttttgga tgataaattt ggacaattga aaatacaaaa aaaagaaagg
     1621 cggtatgaac tcggaaggct ggtaaccttc gtcagcgttc atacacggca ttaagatttg
     1681 gcccttaatg cgttaacctt tcagtgttac ggtattaccc gcaatggatt tagtataaca
     1741 gatattcaaa agtgatacca ctttttttgg ctgtgttaag gttaaaaata cgtgatatta
     1801 cgatgaatct atgcctaagc ataatgttat aaaaatgtcc gtgtggctct ttgccgtata
     1861 acgaacgctg aaattagagg gaacgcatgt ttggatgcgt tccctctttt ttgtttgtca
     1921 tgaacgaaaa tcaattctct atttttgaaa aataacaaga aaaacttgtt aaaaatattt
     1981 aaagaaattg ggtggtttat tttatgtcat atacaggaat tttgagtctc aaagatattt
     2041 gtcactacgg taaacggtgt accgctacag agaaaatcac gaagaaacta tcaactggcc
     2101 aaagtaaaac cgttgtgcag tgtaagaaat atataatcca gaaagacaaa gtctcagagg
     2161 aaatgattta ttacattggg aaacaaaagc aaataatttt aaaagatcct atccccttaa
     2221 aagagctata tccaacaatc aaacatgttt atgaccaaaa cggtgtactg attggtcgaa
     2281 gaaaaaatgg agtcttgcgt tgtaccgcaa aagggatggg gcgtttgatc ggctgaattg
     2341 atcattctca taacttgtat tttatcgttt ttcgcttgct tgaaaatatt gtcgagactt
     2401 ctaaaggaac ttagagtcac tagaaaaata aggagtagac ttgatctatc aacaattccc
     2461 ttcggggagt gacggggtag gttttaacga ttggtaacgt aaaaaattgg tcaatcgagt
     2521 aaatgcgctt gtttggatag tggtgaaatg aatttgtgta aataataagc gcagagtaaa
     2581 caagagggaa tttagaagtt agacaagtta gaatagcgtc tagattaatc atgagcagct
     2641 actaagggat ctagactttg acgcaaactc atggaataag gagtaggtct tctcgtaatg
     2701 gggaggacgc acaagaaatt gtgtcgtgtg ctgcagtaca tgtagatact tgcgaggacg
     2761 ttgattattg gatcaatcga gcatttaccg ctgtctacta gggtttctcg tttcggacgc
     2821 cataaacgag tcgaaatttt ttatgtattt ttaagtaaac gaaaaacgat aaaatatgaa
     2881 caagtcctga ataaagtgaa aaaattaata taaagcatag agaaaatgaa atttacgtaa
     2941 tggaggaatg acaaatgaaa aattatgatc cgaatatacg attgggcaca catactatta
     3001 aggtttcttt ccaacgttgg gattacaaag gatttgtgac gtttagaagg ggcggaaatt
     3061 gtaaaggatt agatgtttta gcattagacg aggatgattt atacgatcaa acattgactg
     3121 ataatccaat tggattcggc ttgctacctg aagatgatga aggtaatgaa tggtttaaaa
     3181 tgacgcttat gaatgataat ggagacgaat tatctgttga agatacttgg tcatatttga
     3241 gtgattatat tgtcagcttt gaaatcattg aatttgtagc ggataaagaa gaataaaaac
     3301 tggaggaata aattttacag ataaaggctt agaaggagtc acgacgatta ataaaaaggt
     3361 agtattacct taggcattga gtaaggaatt t
//
LOCUS       DAZKNV010000128         3264 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000128 DAZKNV010000000
VERSION     DAZKNV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.133"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2177)
                     /locus_tag="ACG8M1_002801"
     CDS             complement(<1..2177)
                     /locus_tag="ACG8M1_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFQ0423448.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVL"
     gene            complement(2849..3117)
                     /locus_tag="ACG8M1_002802"
                     /pseudo
     CDS             complement(2849..3117)
                     /locus_tag="ACG8M1_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          897 a          728 c          527 g         1112 t
ORIGIN      
        1 aggacttcac cactgccttc agcatgttta attagttcaa caccacccgt atcaaggatg
       61 ttttcaatgg ttaacgtcac ttcttctatg gagtattcat ttataaaaac atcatgtacc
      121 gtcgcatcta aaagataccc ttccggtgct tctgtttctc ggacttgata gctacctaca
      181 ggaagcggtt cacttaaaaa ttctccgttt tctgccgtta taccttcttg tatcacttgt
      241 gaatcgcttg ataaaatttc aaattttgct cctgccagcc tttggccatt ctcatcagtt
      301 ttaattactt taatacgccc atcgattttc cttgttctta cagtactcgt attcaatcga
      361 ttgtcactat tcacaagcgt tgcaaagttt aaaatttgat cgccgaccgc atacgcctct
      421 acattgacct taaaagagag ggtaaaactt gtcggaccac caatcgtatt attcgcactg
      481 aaacgaacta ttccattatt gacttcggca tcaatgaaag agggaatatc tgatagaaat
      541 gacacaaatt ccatgccttc ttccaaaaca tcttcaataa caagcgtatt gcttgttcca
      601 gaaaacatcg agacatgcag agtatacgtt agttcatttt cattgagatt gataacattt
      661 ttgtccacac tttttcttaa agagattgcc ggaagattac tttcagggat tctcaagcgg
      721 tagtctcggc tcattacctg attattgtag gtcatactcg ctcgattccg agaaaaccca
      781 tcctcttgtc ttccttcatt gaacaagtcg acatcggtca cttcaagagc atattcaata
      841 aaatacgatt gaccctctgc tagattacca aagtccacaa caagtgtatt cgtttcctta
      901 ttaaaagata ctttgtccac aaattcctcg gaaacataat gagttctaac gtttgcttca
      961 cctggattcg ttacttctgc gatccgaacc ccacctgaaa taggttctct atttccagtg
     1021 gaactccatg tagtcggatt cggtgccaaa gttgttcctt gcggtagtac atcggtaacc
     1081 actacaccgt cttttcgtga tccttcataa tttacctgca aaataaattt attactgttg
     1141 gtcacgtctt gcccgtcaat cagcagattc ccaagatttc cttggctgtc gatttctcta
     1201 gagccatagt ataatttcga aaaaatgggt cttgatgaag gaataggcgt aattgaaaat
     1261 tccgtgtttg ctgctcgctc agcataagta agactcactt gaaagtcatt atttggctca
     1321 gtaccgcctg attgaaagaa agcaacttca aacgtgatac tgaatgtata cgactgagcg
     1381 gcttcattta atccttcata atcaaaggta aatggaaaaa caacgtctgt gccttcttgg
     1441 taaaatgcca gtggctttaa aggtgaatca tcagcgacct ccactctaat gaactcaatt
     1501 aagccaatcg atgctctagg aactcgtacg accatctccc catattcttc aagaatatcg
     1561 ccagcgcctc cttgaatgta tccctttaac gtttgtgtat gcctgctcgg caaagtgggg
     1621 cgctcagcag agatgccgat gtcataattc aagagctcct cttgtctttc aatctgagat
     1681 tcctgcgtta tagatggctc agatgatctg gcttcattaa aagattcact taagctttct
     1741 tctggtatat taaaagattc acttgtgctt tcttctggta cattaaaaga ctcacttgtg
     1801 ctttcttctg gtacactgat ttctattgag accgtatttg attgaatatc accgcttctt
     1861 gcggtcaatt cgtatttacc tgaatgctgg gaagaataag taatcagacg ttcgtaatca
     1921 ttgagttgct tcacttcccc ttcaatcaaa tcctcactct tatcaatgac caatgcattt
     1981 agcaggtctg gtgttcctct gactcgcaac tggaactgct cacccaaagc agcctcctct
     2041 tgatcaactt cgatcgtcag cgaacgctct ggctgttctg ctaaagactc agctagaacc
     2101 gttatgttcc caaattgatt gatcacaata agcataacta gaaacatact taacagttta
     2161 tgaaatttgt tcctcactat tactccccct tataattttg actaaacaac aaggtacccg
     2221 ataattttct aaaaagattc cccaactcaa aatggctgcg ttacctccct cgtattttcg
     2281 gttcaactca agcgttgcaa tgtaagctgt aaacaaagct aatgattgcc gattgtcttc
     2341 tgttgattga ttcgatagct ttgtatgact tttagttgtc cgtgtggctt aaccataatt
     2401 atgatttcac gattcctcct gccagtgcct tgcacaagct ggagcgtaac cctaatagtt
     2461 attttgttaa tgtacttata tacttttata cttttccatt agaaacaatc actaaatcgt
     2521 tgataccaag gtcagactct agaatttcat cagtgagtcc ctgtattggt taaccttcat
     2581 caatcccaaa aaaatatatc aatgcttagc atcaaaatga atatatagtt tagaatactt
     2641 gggattcatc gataactgat cgcttatttg gccatattat ttggcacttg gttcaactaa
     2701 acgcatttag gatgttcctt cattctcgtc atggatgttc tcaaaccgtc attactaata
     2761 aactgtccac cgaatcgatg gttcatttct tgcattttcc acgtccaatt actctttttg
     2821 ctctttattt gggcgtagtt ttactttctt aacttgtatc gtcttccatc aactccttaa
     2881 tcatcttctt agctttattg gctcggtttc cttgtaaaag gtatctacaa atagtgacaa
     2941 tctgtattaa atcttcatca ttttctgtaa tgtcaataat ttctatattc tgtaccatat
     3001 attgcaaagg gtttcactaa gttcataacc gaagcgaatt aaacaacttt tgtatagaat
     3061 aactaccttt tctatttttc cattggtaat tctatctatt aattggttta atccttttgt
     3121 tgtagttgat tccactacca agatgattct ctcgaatttt aaagcttgaa gatgtattgc
     3181 tatttttgct aactggcgta tttgcaacta tttttccctt ctattcttcc ttcattgatt
     3241 cccctctaaa attactatcc ataa
//
LOCUS       DAZKNV010000129         3172 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000129 DAZKNV010000000
VERSION     DAZKNV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.134"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(559..1599)
                     /locus_tag="ACG8M1_002803"
     CDS             complement(559..1599)
                     /locus_tag="ACG8M1_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0423449.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1948..2274)
                     /locus_tag="ACG8M1_002804"
     CDS             complement(1948..2274)
                     /locus_tag="ACG8M1_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423450.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2261..3049)
                     /locus_tag="ACG8M1_002805"
     CDS             complement(2261..3049)
                     /locus_tag="ACG8M1_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0423451.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
BASE COUNT          949 a          540 c          445 g         1238 t
ORIGIN      
        1 cgttgcgggt aataccgtaa cactgaaggg cacgcattaa ggcgtcatct taatgctttc
       61 ctgtaggaca ctgacggaga ttaccagtct cccgagcctt acaggggcct ttcttttttt
      121 tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
      181 aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
      241 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
      301 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
      361 tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa aacctacgtt
      421 tgtgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta tttatttgta
      481 acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata
      541 gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg gtaattcgtt
      601 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt
      661 ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg
      721 ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat aagattccag
      781 ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg cattatgaat
      841 agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta tcaagtttaa
      901 tacattttct ggtacaaatg tatttatact gtcctctttc atgatgtcga cgaagttatc
      961 tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc tattagtgtc
     1021 tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat
     1081 atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat tgatttctcg
     1141 cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt cttcctcttc
     1201 catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca ataaattagg
     1261 catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt tcagaagacc
     1321 tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt gtaacaattt
     1381 cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta cccagttatt
     1441 tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga
     1501 tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg
     1561 ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg
     1621 atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat
     1681 atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt
     1741 ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg tttaagctca
     1801 tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat attacaatat
     1861 gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata
     1921 ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata
     1981 tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta taacgtctgg
     2041 tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg
     2101 atttatacga atgctatctg ctgttcttac actacttcct tgatctttta tgactttact
     2161 tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat tctttttatt
     2221 tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat
     2281 caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg
     2341 gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgtcc
     2401 tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag
     2461 acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga actcctcgta
     2521 cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta
     2581 gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa
     2641 atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt
     2701 tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt
     2761 ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca
     2821 gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg
     2881 ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta
     2941 aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag
     3001 ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc
     3061 ccattcatct tatattataa tataattata tcataatatt gtgatattgc aatatcgtat
     3121 atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat cg
//
LOCUS       DAZKNV010000130         3153 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000130 DAZKNV010000000
VERSION     DAZKNV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.135"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(18..716)
                     /locus_tag="ACG8M1_002806"
                     /pseudo
     CDS             complement(18..716)
                     /locus_tag="ACG8M1_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            795..971
                     /locus_tag="ACG8M1_002807"
                     /pseudo
     CDS             795..971
                     /locus_tag="ACG8M1_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1147..1716)
                     /locus_tag="ACG8M1_002808"
     CDS             complement(1147..1716)
                     /locus_tag="ACG8M1_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0423452.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1790..3079)
                     /locus_tag="ACG8M1_002809"
     CDS             complement(1790..3079)
                     /locus_tag="ACG8M1_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423453.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
BASE COUNT          878 a          633 c          551 g         1091 t
ORIGIN      
        1 aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt gtcatgaaaa
       61 tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat catgacgtat
      121 actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac atttcctaaa
      181 gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac tctagctagt
      241 tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt agcaatgtgc
      301 catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat gtgggcgtaa
      361 tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc aattactggt
      421 ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc ataggctagt
      481 ttttctttac ttacacccat ttcagaaaga taaccgtaag gatctgtatg atcgccccaa
      541 atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg agtgtctaat
      601 gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta tactttatag
      661 ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac aggacttttg
      721 gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg aaaacaccaa
      781 cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta gaagatatca
      841 aagatttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat atttctcccg
      901 aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa ataaaaaagc
      961 actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa ttttatttat
     1021 aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt atcttaaagg
     1081 cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag tgcgaacatg
     1141 gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca tcaattgaga
     1201 ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg gttttcttct
     1261 taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca cgactccgcc
     1321 aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta gattttttgc
     1381 tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct cttccatccc
     1441 ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta tttcttttgg
     1501 ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca agagcgtttt
     1561 gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata tatatacgcc
     1621 agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca cttctgtgat
     1681 cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt tactaatcgc
     1741 tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt tatcggtttt
     1801 tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa ggatggtaca
     1861 gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcggtg atcactagat
     1921 ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt tttcgatgtc
     1981 ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca tagcgaaaaa
     2041 aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc tggagtgttt
     2101 tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg atcgctagcc
     2161 gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc tgataataac
     2221 gaacttcttc tatcagccgg tcatggatac caattacgta acgaagccat tcttggtaaa
     2281 gtacttttat cagctttgat ttgctttcgc tctcaaattc gctattcagc caaaacagcg
     2341 aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct tctatccgtt
     2401 tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga taattttttt
     2461 cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat tcaaagaata
     2521 gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc ttcaataatt
     2581 ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc ggaaaatctt
     2641 tcaaaaagta aaacagcaga tatcttactt ttctttctga accaaagatc tgtgcttttt
     2701 tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct tgcgtagaac
     2761 gatcgtactt ctgctcgtaa ggttcattta atagcagatt tttcagtaaa caaaacgggg
     2821 gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga tcataaacta
     2881 actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc gccaaacgtt
     2941 tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa tcagcttttc
     3001 gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca ttttttgata
     3061 atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat tgtttgatca
     3121 aaatgagttc actcctaaaa agataaaaaa ctc
//
LOCUS       DAZKNV010000131         3022 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000131 DAZKNV010000000
VERSION     DAZKNV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.136"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(287..649)
                     /locus_tag="ACG8M1_002810"
     CDS             complement(287..649)
                     /locus_tag="ACG8M1_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423454.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="ACG8M1_002811"
     CDS             complement(723..1103)
                     /locus_tag="ACG8M1_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFQ0423455.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="ACG8M1_002812"
     CDS             1185..2360
                     /locus_tag="ACG8M1_002812"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFQ0423456.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2436..3020)
                     /locus_tag="ACG8M1_002813"
     CDS             complement(2436..3020)
                     /locus_tag="ACG8M1_002813"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0423457.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          942 a          577 c          498 g         1005 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atatttattc aaaataaaag gacgagacct tactaggttt
     2401 cgtccttttt cataattact ccgtaccata ccaaactatt ctgaaatttc aattgtttca
     2461 atcactacat catgtacagg tcggtcttgt ggaccacgtt gtacatttgc gatttcatct
     2521 actgtgtcca tcccttctag tacatgtcca aagactgtat gtcggaaatc tagccaagga
     2581 gttccgccac ctttatacgc ttcaatgatt tctgatggga atccagcacc ttctagttgt
     2641 ccaagcatat tagctggcac atttgtgtta tttacaataa agaattggct tccgtttgtg
     2701 tttggacctg aatttgccat agataaagct ccgcgaaggt tgaacagttc acgactgaat
     2761 tcatcttcaa aactttcgcc ataaatactt tcgccaccca ttcctgttcc agttggatcg
     2821 ccgccttgga tcatgaaatc aggaataacg cggtgaaaaa tcacgccatc ataataacct
     2881 tttttggaaa gttcaatgaa attttgaacc gtcttcggtg ctagttcagg gaataattga
     2941 acagtaatgt caccacggtt tgttttgata acagcttttg gtcctttttc actttttaaa
     3001 tctagttgtg ggaatgccat at
//
LOCUS       DAZKNV010000132         2999 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000132 DAZKNV010000000
VERSION     DAZKNV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.138"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            155..1051
                     /locus_tag="ACG8M1_002814"
     CDS             155..1051
                     /locus_tag="ACG8M1_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0423458.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIVHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
     gene            1143..1358
                     /locus_tag="ACG8M1_002815"
     CDS             1143..1358
                     /locus_tag="ACG8M1_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFQ0423459.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            1376..1648
                     /locus_tag="ACG8M1_002816"
     CDS             1376..1648
                     /locus_tag="ACG8M1_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFQ0423460.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILTKEKVA"
     gene            1650..2513
                     /locus_tag="ACG8M1_002817"
     CDS             1650..2513
                     /locus_tag="ACG8M1_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFQ0423461.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKYVTPYSNRMTEAI
                     ISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGI"
BASE COUNT         1182 a          479 c          520 g          818 t
ORIGIN      
        1 gataaataga ggtctttcca ctactatcta aatggaaaga cctctatttt tcatatagga
       61 gctacttttg ggtcagccct atatattaat cacaaatcac ttatcacaaa tcacaagtga
      121 ttaatcacaa atcacttgtg atttgtgatt cttaatgata caatattact atacaaaaaa
      181 agaatggggc gtagttatgg agaaggaaaa actaaaaata cttgaagaat taagacgtat
      241 tttaaacaat aaaaatgaag caattattat cttgaataat tactttaaag gtggtgttgg
      301 aaagtccaaa ttatcgacta tgtttgctta cttgacagac aaattgaatt taaaagtttt
      361 aatgatcgat aaggacttac aggcaacatt gacaaaagac ttagcaaaaa cttttgaggt
      421 agaattgcca cgtgtcaatt tttatgaagg cttgaaaaat ggaaacttgg cttcttctat
      481 tgttcatttg actgataatt tagacttgat ccctggcacg tttgatttga tgttactgcc
      541 aaaattaact cgctcatgga cttttgaaaa tgaaagtaga ttgcttgcta ctcttttagc
      601 acctttaaaa agtgactatg atctcattat tattgatact gtaccaacgc caagcgttta
      661 tacaaataat gcaatcgtgg cgagtgatta cgttatgatc cctttacaag cagaagaaga
      721 aagtacaaac aacattcaaa actatatttc ctatttgatt gatttacaag aacaatttaa
      781 ccctggacta gatatgatcg gttttgttcc ttatttagtt gatacggaca gcgcaacgat
      841 aaaatcaaac ctggaagaac tgtacaagca acataaagaa gataacttgg ttttccaaaa
      901 tattatcaag cgaagtaata aagtaagtac ctggtctaaa aatggaatta cagaacacaa
      961 aggctatgac aaaaaagttt tatccatgta tgagaacgta ttttttgaaa tgcttgagcg
     1021 aattattcaa ttagaaaacg aaaaagaata gaatcacaaa tcacaagtga ttaatcacaa
     1081 atcacttgtg atttgtgatt gttgatgata aaataagaat aagaagaaat agaaagaagt
     1141 gagtgattgt gggaaattta ggcgcacaaa aagcaaaacg aaatgataca ccaatcagtg
     1201 caaaaaaaga tataatggga gataagacgg ttcgtgttcg tgctgactta caccatatta
     1261 taaaaattga aacagcaaaa aatggcggaa acgtaaaaga agttatggat caagccttag
     1321 aagaatatat acggaaatat ttacctgata aactttaaaa aggagtgaaa atgaaatggc
     1381 agttacgtat gaaaaaacat ttgaaataga gatcattaac gaattatcgg caagcgttta
     1441 taatcgagta ttaaactatg ttttgaacca tgaactagat actaaaaata ctcgtttact
     1501 agaagtgaat cttttaaatc aattagaagt ggcacaagaa gttgatttat ttcaacaacc
     1561 atttgaagaa ttacaagcta ttcatgagta ttggcggtca atgaatcaat attcaaaaca
     1621 aattttgaca aaagagaaag tggcttaaca tggcgaatat tactgacttc accgaaaagc
     1681 aatttgaaga tcgtttagaa aagaatgttg aacgactaac taaaaataga ctagcggttg
     1741 aatcgccaac cgctttttta cttggtgggc aaccaggatc aggtaaaact agtttgcgat
     1801 cggcaatttc cgaagagaca caaggaaatg ttgttatcat tgataatgat acgttcaaac
     1861 aacagcaccc taattttgat gaactagtga aactttatga aaaagacgta gtaaaatacg
     1921 ttacccctta ttctaatcgc atgacagaag cgatcataag ccgtttgaga gataaagggt
     1981 ataatttagt gattgaaggt acaggacgaa caacagacgt tcctattcaa accgcaacaa
     2041 tgcttcaagc caaagattat gaaacaaaaa tgtatgtcat ggcagtacct aaaatcaact
     2101 catatttagg aacaattgaa cggtatgaaa ctatgtatgc agatgatcca atgacagcca
     2161 gggcaacacc aaaacaagcg catgatattg ttgtcaaaaa cttaccgacc aatttagaaa
     2221 cccttcataa aacgggctta tttagcgata taaggcttta caatagagaa ggagtgaaac
     2281 tctattcaag cttagaaacg ccttccatta gtccgaaaga gaccttagaa agagaattaa
     2341 atcgtaaagt atcagggaaa gaaattcaac cgactttgga gagaatagag caaaaaatgg
     2401 ttcaaaatca acaccaagaa acccctgaat ttaaagcaat tcaacaaaaa atggaaagct
     2461 tgcagccacc tacaccacca atacccaaaa cacctaaact tccagggatt taaaccttaa
     2521 aaaagtaaaa gagtagttac caaaaaacgg taactactct ttttttataa aaacatttcc
     2581 tcatttttta aaagctgatc gagaaataaa gcacacaact gtattctttc ttttttcagt
     2641 tggtacattt tgcagtctgt aacgtgccat ttactgtttg ttaccttaac atatccagtc
     2701 gaaaacacaa gggtatataa acgagcaagc tcgcccttgt gttttctttg tgtctatgtt
     2761 gcgttctcgt cacagcaaac gacacgaaca cactggcgaa aatgaaccaa caaaacgaaa
     2821 aaagaaagga gcgtacactg taatttattt ctagctttta aaacatgagg aaaacagctt
     2881 cacttcctca aacgcctaac aaaaatggtt gtcaaaaaac taaaaatcaa aaaaagaaaa
     2941 gaggaaaaga aaatggaaaa aacaaaaaaa ttacaattag aagattttac agaaaatgg
//
LOCUS       DAZKNV010000133         2893 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000133 DAZKNV010000000
VERSION     DAZKNV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.139"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(568..1320)
                     /locus_tag="ACG8M1_002818"
     CDS             complement(568..1320)
                     /locus_tag="ACG8M1_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0423462.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(1335..2582)
                     /locus_tag="ACG8M1_002819"
     CDS             complement(1335..2582)
                     /locus_tag="ACG8M1_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFQ0423463.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(2658..2804)
                     /locus_tag="ACG8M1_002820"
     CDS             complement(2658..2804)
                     /locus_tag="ACG8M1_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFQ0423464.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
BASE COUNT         1006 a          473 c          353 g         1061 t
ORIGIN      
        1 aaatttttat cttttattaa agtcagataa aaattctttg gaaatgtaat ggtagagata
       61 tttttacaaa aggacttgca gcgctgtagt tggtgctgca ggaggaccta tttcggccgt
      121 tacaggaggt attggtaatg tacttgtcgg atgtgcatta aagcctgttc ctgcaagtta
      181 aatttataaa aacaggaaag taattatctc aaatcctatc aagtacaatc ataggattgc
      241 acttgacagg acaaattttt taactaaaaa atgaaaaaca ctttctaaaa attagtagaa
      301 tttgccaaat ctttcgcatc ttccaccata catttaattt taattcccct ttatggtact
      361 taataaaaac aagaaaagaa ctattcattt ggcccttttt tggttccaga ccatagaaat
      421 attcctccag taactaatat tgctgttatg cacgtaacta ataacagcta taaaaattgg
      481 tacaacttta ataggattca gaaaaatttg cactagtgaa ggaatctatt ttattagaaa
      541 aatgcaatct ccctaaagaa aaaaccacta aacagtgctt tctttcaact tctccttaat
      601 tttttgtgct ttccctaaag taaagtttct ggccaactct gaatcaaaat atagtgaacg
      661 ttttttaaaa tctatttctt taacgttaaa gatatttact aaacacgctc gactaattct
      721 tgttaacata ggatatttct tttcaagctc actaattctt ccataaaatt cgtactgccc
      781 atctttagta cacaatgata atctatgtgg taattttgaa gcttctacaa aataaatgtc
      841 atttatatca aaagtaaatg tttgagaacc tatggaaaaa acaaatgctt gattcgtaac
      901 ctgttttgtt gcatctatcc tttcttgcgc taataacaat aactcaacaa tctcgtttcg
      961 atactcatct agtgtttgat cttttgttac aaatcctaac gtttcaactc ttctttttat
     1021 tgttacgggt aacatctcat catgagtagt tgtaaaaatg atttttgctt gaacatcata
     1081 ttttctgatt acttctgcta attctatacc gttaacttca tgatttaaat caatatctaa
     1141 gaaatatatt ccttgctttg gtcggaattg tttgaggtat tttttaactt ctaacggact
     1201 ttgtgttttc aatactatct taaatacttt atcgtgaaaa agaatgaaat tatcaataat
     1261 tcgttctaac tgatttaatt gtataatttg atcttcacat aatattattg gataactcat
     1321 aaatcctcct tccctcaaaa caacaaaata acttgagtag taaattgata cggatcgttt
     1381 tgatagttca caaacatatt gggattcttt ttattgattt cctctatact agataaacct
     1441 aacccttgat gtcccttttt tgttgttatt ccttttttca ttagagtatc tatagagagt
     1501 agtatctctc tacaactatt cgatatcgaa atttctatct gtttatcatc tcggtaaata
     1561 gctagagaca gttctctatc ttgactctct atagatgctt caattgcatt atcgagaata
     1621 attccaagca ccctaataca gtcaaatatt ggaacaggaa cttcaataat agtacttgga
     1681 cattcgaatt tacaacaaat cttattgtta tttgcttggt atagcttcgc tatcaacaaa
     1741 cttttcaaat attcattttt tatatttttt aaataacgat attcaaactt attggttaga
     1801 taagaattag aatagatctc taattctttt atttcttttt ccaatatcga atcatggttt
     1861 tgattagcga tttcttttaa actcagcaat aaatttttat agtcatgtct aaatctggca
     1921 aatttttctt gatctttttc cagtgaatca gtatattttt ttagataaac caattctttt
     1981 cttttcaatt gctgttcata ttgttctcgt tgcctaatag ttattctaat aaataaaaat
     2041 agaacaacaa acatttgaat gattaaaaat attaagacac caaacacaaa atgatcaaat
     2101 acttgatatt gatgagcaac ataagaaaca aataaaccaa ttgtaagtaa ataaatcatg
     2161 aatatagcag taagtttaga actggactgt tcaacaatcc tatttatagc taattttcta
     2221 tataaccaaa taaacatcag caaaaacaaa gaatcaagca ttatctggaa tactacataa
     2281 ccataccctt ttatcccttc aaatgaaaac atatacgtca taaccatgga agtaataata
     2341 gatctgaaat catcaataag catacataat agtaatttat ttaaaagcac tatattagtt
     2401 ttcttctttt cctttaatat aaaataactt ccgattatag gtatagctgc ggaaacatca
     2461 gtaaataatt caacaaaaaa agtgagtggt atcaataaac atacaaaaag atattttctt
     2521 ttgttaagat cagtattagt catataaaat aagagaaaaa agaaaaagtt tcccacgaac
     2581 attcttaata gataagcttt tgtatcgata gtaatcaaga gatcccctcc tgattttagg
     2641 atatcataaa aaaaatttta gttacacttt ttaaataatg aaaaaacaca ttccactaaa
     2701 tttgatgccg gttttccttg aggttttgtt ccagcacctc ctttaatttt tttaagctct
     2761 tgatctgaac attgtttagc atttagtcta tttttttctt ccattacgat tccccctaca
     2821 aactataaat acttttatgt cactgattca atatacctat ttttctaatc aaaaaatttt
     2881 gagacatatt taa
//
LOCUS       DAZKNV010000134         2491 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000134 DAZKNV010000000
VERSION     DAZKNV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.140"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1335
                     /locus_tag="ACG8M1_002821"
     CDS             <1..1335
                     /locus_tag="ACG8M1_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423465.1"
                     /translation="IDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1322..>2491
                     /locus_tag="ACG8M1_002822"
     CDS             1322..>2491
                     /locus_tag="ACG8M1_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFQ0423466.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKN"
BASE COUNT          831 a          377 c          420 g          863 t
ORIGIN      
        1 atagatgctg cttttttatt tagttgttta tatacttttg caacttatcg aacagttgat
       61 atctattatc gatccgcaat tgcagaagca atcgctctta cgattatccc agctgtttta
      121 tattatgctt atggattgat attcaataga gaaaaaaaag tcatcgcttt atctgtcagt
      181 ataagtctac ttgtgtatac tcatgtctta actacactat tgtgtagtgc attgattgct
      241 tgtatgatta tagttcgttt gtttttaagc aagcaaataa aaaacgatat aaaatttgtg
      301 gtcgtgaatt tagtaaaggc tgtttttttg acttgtgcat taactagcta tttttggtat
      361 cctatgttgc agcagatgaa ttatcaagaa atacacagtc ccttcaaaac agatttgcag
      421 ctagaagcac tttctatttc agatagtatc attcaagcgt taaataacga tattacaaca
      481 tacactatgg ggttattagg attggttgcg ttgatttttc ctttattcat actgaaagaa
      541 atggagaaaa aagaaaaaat catctatgtt ggcgtagttt ctacatgggt atgcgtaact
      601 aatttatttc catggttttt gtttcaaaaa acaccgataa gcttactcca gtttccttgg
      661 cgtatcttag gtatccaaat ctttttttct tcaatgatca taacgcttgt ttttatgaaa
      721 aagactatga ataaaaaata ttcatggtta atcattggcg ctactgtggt gtttctactc
      781 gtcacgtcta tagcagcaaa agaaaattac gcaaaagtta tccaatcaaa acacggtcat
      841 attgttatca atgaagaaac actcccacgt tatacaacat cagatatggg aggattatac
      901 gattacgccc caacagaagc gataaaagaa aggcctcact tagaaaaaca tgaagtaaaa
      961 gtaggagaat cgtgggaaaa agggaagtat aaagctgcag ataataacat tacttacaca
     1021 gtggcaagca acaaaaagca aaaagtgaca gtaccagtat atgcttattt aggtacacag
     1081 gtaaaagtaa acggtaaagt cgtaaatgac tcttataaaa aacatggctt agtgaatgtg
     1141 gatgtaaatg ctggagaaaa taagatagaa attacaacaa aatatactcc aactgctctc
     1201 atggctttat ggatcagtat tctgacttat tgtttagtgg tgtattcaag ttttaaacga
     1261 tttgcaccta ataagttgaa agattctcga tatgtgacta aaaaggagat aaacaagaag
     1321 aatgaaaata aataaaaaag tagtaatatt gagtggatta attatagtta gtagtatata
     1381 ttctttcatc tttttcaaaa atacacagag tatttatacc actggagatc tttcttttca
     1441 cttatctcga atcaaggggt tatcgactat ttttaccagt ccgattaatt atgagacatt
     1501 caattatact ggatatggtg taaattattt ttatcccttt ctgacttttt ttccagctgt
     1561 aatgttatat tggatgacaa aaaatttgat tgtaagctat attatttacg tttggttatt
     1621 gaacttgtgt acaacactcg tagcttatca ttatggcgag cggtttttaa aacaaaaaaa
     1681 agcggcattt ttatttagtt gtctctatat tttctctgct tatcggacag tagacatcta
     1741 ctatcgttcc gcaattgccg aagctatcgc aataacactt gttatccctg tattatttta
     1801 tgcttatcaa atcatctctg gaaaagaaga aaagtatccg tctgtaaagc tagcattgag
     1861 tatgagtttg ctagtgtaca gccatgtact atcaacatta atgagtacag cattaattat
     1921 catttttatt tttattcgtt tggtttctaa aggtttcaag aatgcagatt ttattgctat
     1981 atttaaaaaa ttatttagtg cggcaggaat gacattggtt ctgacgagtg ctttttggta
     2041 tccgatgttt gaacaaatgc tctaccaaaa aatcaacaaa cctagcgtga caaatttata
     2101 tgctcatgca tctaatgtgt tcgatagtct gactgaagct atgaacaacg acttaactac
     2161 ttactcaatg ggactagttg gtctgttatc tttatgtatt cccctgattt tatttaaaaa
     2221 attaacaaac atagaaaaaa agatttatta tggtacgtgt ttgacttggc tagctacaac
     2281 tagtttggtg ccatggtatc ttctgcaaaa tacgccagcc aaattgttac aatttccttg
     2341 gcggatctta agcttgcaaa taatattctc ttctctgata ttaacgatga tatttttcaa
     2401 aaatagaaga tacaataaga caagagaact attttattta tttatgactg ttttgttatt
     2461 aatcacttta actgtttcta gtaaaaaaaa t
//
LOCUS       DAZKNV010000135         2478 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000135 DAZKNV010000000
VERSION     DAZKNV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.141"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..300)
                     /locus_tag="ACG8M1_002823"
     CDS             complement(<1..300)
                     /locus_tag="ACG8M1_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFQ0423467.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACG8M1_002824"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACG8M1_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACG8M1_002825"
     CDS             complement(1014..1304)
                     /locus_tag="ACG8M1_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423468.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2203)
                     /locus_tag="ACG8M1_002826"
                     /pseudo
     CDS             complement(1512..2203)
                     /locus_tag="ACG8M1_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          731 a          457 c          347 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgatttct acatttgttt
     1681 tttcttgtgt cagtgttgcg atttgttgat tcaaaccatt tacagtattt tgtaattctg
     1741 aaagttttgc ttgtgcttct tgtagtcttg ctgtccaatc tgcattcaga tgattgattt
     1801 catcattttt ttggttgatc tcatctagtt tgacattgat ttcattttgt ttgctttgta
     1861 gttgtgcatc cttgctgact aattgacttt ctaagttttg tttttctgct gccgattgat
     1921 ttttttggtt ttctaattca tttacttttg tttggtattc ttggacatct gcctttgaat
     1981 cttgcaatgt ctgttctttt tgtgctagtc gagcggtaag atctgtaatc gcttgctctt
     2041 tatctgtcaa tgtatgatca agctgtgtca gattctcatt gattgtatca atatctgtct
     2101 ctccacccca caaaataatt tcatttgcgt accgcgtgcc tgtgtagcca attagacata
     2161 gaaatgcaac gacaatccca ccagtaataa atttcttttt catttgcata gctccttaat
     2221 ccaatacttt tacatgctaa aagtaagtga tctcaaacac aatgtcaagc gtttttaaat
     2281 tacatatgta attttaatat aaatactatc aaatactcat ttaatcctcc ttttttatct
     2341 atttaaaaaa tcttttttat agagaaaaat gcaggttaat actttcttaa ataaatattt
     2401 atggtgaaca aaaacaaaaa agcaagtttt attaaacgta acccttttca tttcatagat
     2461 tactgtattt attacaaa
//
LOCUS       DAZKNV010000136         2459 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000136 DAZKNV010000000
VERSION     DAZKNV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.142"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1282
                     /locus_tag="ACG8M1_002827"
     CDS             <1..1282
                     /locus_tag="ACG8M1_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFQ0423469.1"
                     /translation="NTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEG
                     EKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKD
                     TVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVD
                     VSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASE
                     GIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNK
                     PQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIV
                     TATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPK
                     TGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1416..>2459
                     /locus_tag="ACG8M1_002828"
     CDS             1416..>2459
                     /locus_tag="ACG8M1_002828"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFQ0423470.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTAR"
BASE COUNT          968 a          338 c          489 g          664 t
ORIGIN      
        1 caacacacca ggtaattacg aaggtgtcat tgaagtaacg tatccagacg gtacgaaaga
       61 tacggtgaaa gttccagtag aagtgacaga caatcgttct gacgccgata aatatgaacc
      121 aacagtagaa ggcgaaaaag tagaaattgg aggcacagta gatttaacag ataatgttac
      181 taacttgcca gcgttaccag aaggaacaac agtaacagat gttactcccg gcggtacaat
      241 tgataccaac acaccaggca attatgaagg tgtcattgaa gtaacgtatc cagacggtac
      301 gaaagatacg gtgaaagttc cagtagaagt gacagacaat cgttctaatg cagataaata
      361 caatcctgaa ggacaaaaag tgactacaga cttaaataaa gagccagatg catctgaggg
      421 aattaagaac aaagaagatt taccaaaagg aactacttat gcttggaaag agaaagtaga
      481 tgttagcaca gctggaaata aaaaaggtac tattgtagtg acatatccag atggatcatc
      541 tgatgaagtt gaagtagacg ttacagtgac agatactcgt tccgatgcag ataaatataa
      601 tcctgaagga caaaaagtga ctacagactt aaataaagag ccagatgcat ctgagggaat
      661 taagaacaaa gaagatctac caaaaggaac tacttatact tggaaagaaa aagtagatgt
      721 tagtacagct ggaaacaaaa aaggtactgt agtagtaaca tatccagatg gatctaaaga
      781 agaagtagaa gttactattt ctgtagtaga taaaaaagca ccgaataaac ctcaagttga
      841 tcctattaca gagggtgacc aaattgttac tggtaaaact gaaccaaatg cagaggtgac
      901 agttacatta ccagacggaa gtcaacacca tgggacagct gataaaaatg gtaattttac
      961 agttaaagtt cctaaattag aggcagggac aaaagtgata gtaactgcaa ctgatgaatc
     1021 tggtaatact agtgaaccta ctaatgtagt tgtttcttcc aacaaaaaag acagtggaaa
     1081 aaacggtagt aaaggtagta agactgacaa tcaaggtagc aacagcaatc aagacaaaaa
     1141 tagaggcaaa agccagtcct caaaagtttt tcctaagacg ggagagagtg acagtaatat
     1201 ctttactatt agcggtggtt taatactgtt aggaacgtta ggattattag ggtataaaaa
     1261 tcgaaaaaaa gagaatgaat agaaaatcaa tttcttaagt cttctctgag aagaggaaga
     1321 atctttttct tcctcttttt gcttttttat gatgggaaat aagtgttagt taaagatgaa
     1381 tatacttttt atagaaagga aaagaatgta attaagtgga aaaaatagta attattggtt
     1441 caaaccattc agggctagcc gcagctcgat ttctaaactt aagcgattca aattatgaag
     1501 ttattctaat cgataaaaaa tcagaaatta gttacttgga atgtgggaca tcgttattta
     1561 taaaaggaga agtaagtaat ttagaagatc ttttttatca aaatagaatg acactaaatt
     1621 ctgagataaa aaagttattt ctagagacag aagttgacaa aattgatatt caaaataaaa
     1681 agattagttg tgtaaaaaaa gatggtacaa gattctctca agaatatgac aaagttatat
     1741 tagctacagg ttcaaagcaa attatgctag atataccggg gaataattta gctaatattt
     1801 tttcgataaa gaattttcca aatgcaaaag agatttttaa agctttggat gatagtacta
     1861 ttaaaaaagt aggaattatt ggagcaggat atattggagt tgaaattgct gaagccataa
     1921 gaaaaagagg gaaagaagta tatcttttcg atgttgcaga tagagtgttg tcgacttatt
     1981 acgaccgtag tttttcagat aaagttgaag aaatactatc aaaaaatgga atacatcttt
     2041 gtctatcaga aagtcctaaa aaatatttag gaagaaaaaa gattgaaaaa atagtcacta
     2101 caagtggtac ccaatactct atggatatgg tcgtacaagc tataggattt ctatctaata
     2161 gtccaattgg ggaaaaggaa ctcttgagag atgttagtgg agcatatcta actaatgaat
     2221 accagcaaac aaatataaaa gatatatatg ctattgggga ttgtgctaca acttttttta
     2281 cgtccattaa tagaagtagt gttgattttt ctatttctaa tgctctaaga acagcttata
     2341 ttgcaactca acatattaac aatcaagatt ttacaccttc tggttcccaa tttacaaatg
     2401 gcttttctat atttaattac aatttttacg cagcaggttt gaatttaaaa acagcacga
//
LOCUS       DAZKNV010000137         2449 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000137 DAZKNV010000000
VERSION     DAZKNV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.143"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(8..292)
                     /locus_tag="ACG8M1_002829"
     CDS             complement(8..292)
                     /locus_tag="ACG8M1_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423471.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(992..1087)
                     /locus_tag="ACG8M1_002830"
     CDS             complement(992..1087)
                     /locus_tag="ACG8M1_002830"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFQ0423472.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            1762..>2449
                     /locus_tag="ACG8M1_002831"
     CDS             1762..>2449
                     /locus_tag="ACG8M1_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0423473.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLP"
BASE COUNT          798 a          393 c          456 g          802 t
ORIGIN      
        1 ctcatggtta tatcattcct ccgataagca tttcaatgat ttgattattt gtgtagacat
       61 actcgcttaa tatttgagta ttttctgttt ggatagcaat aaatttatcg agcaataaat
      121 cgaattggtc ttttttgtaa gtcgtaagtt gacggtcaaa atcactttcg attaaaactt
      181 ttagatattt atttcgactc catttttctc ctgttttatt cgtgagttct tggcaacgtt
      241 tgtctattgt tgcaacaaac tttggatcaa tattccgaac taaaatgtcc ataaaaaatc
      301 tccttttgca attatgtata atttatgtat accatacaaa tactatattt gtatagctgt
      361 tttttgccaa aatgctatac ataagctacc cacgatggcg aaaaagtgat atcaaatttt
      421 tttctgagaa acgtgatagg cacagcctat ctacccactt tttttagaaa gtgggtacac
      481 gtttccttat gctctttaaa attcgggggg gagtgctgca cgtgtaatcg ataaccaaat
      541 ttaacagacg aaaaattgtt ggaatataaa aatatgacac ccgaaagaaa acgatcgttg
      601 gaaaaattaa tgcaactagt gaacgaagac ggcggaattt cagacgcagc ttttgacgca
      661 tggagcgaat ttcatggaga atataattaa gtgggtttaa atggctctaa aatcgcttct
      721 aagagttttt tagcttggac caatgaaata caccaaaaac taaataaaac gtcttaaatc
      781 gaaaaatacg agctctcaga gcgactttat ttgtaaatgt tgcatataag aaataattac
      841 ggattttaga cttttgtagg atatttttga aataaatatt tatttctgtt ataatttgat
      901 tgcaaataag tgaacacgaa acacacgaaa tccccagaga ggtcggattc tctggggctt
      961 tttttgtggg ctgagtcgcc ttaattaagt tttacttctt gtttcggtta ttcaaccagt
     1021 aactgaacaa agcgcttaaa agcccaacaa gaagggagca aataaagtta gtgaacacga
     1081 aacacacctc cttccagtcg caagactgtc ggataggcga caatcaatta tacaataaaa
     1141 aagcaaaaat aagcctaagt tttttattgc cttggggttg ttagggcttg ccctgaccgc
     1201 ctgtaaggcg ctttagaacg aaggacatag tttttatcga atcttgtctt agaacggctt
     1261 agacgagctc tcaggacgcc acaaaggagt ccctaatgaa ttatttttgg cgaaggagcc
     1321 taaaggcgac tgctgcaagt aaaatgtgag agcgtagcga tcactccttc ttacagcgac
     1381 catagggagc tagattggca gtttaatatc atgcgcgaac ctgtttattt taaaaagtgg
     1441 gtgatttttt ggcgggaaat tttgctcgcg cgcgcgcgtt tattttattt attttttaaa
     1501 gattttttag aacccttttt agggggcagt tgagccttac tctcccaacg gatacagaag
     1561 ggtactaaca actttttatc tgagtactaa caacttttta tctgagtact aacaactttt
     1621 tatctgagta ctaacaactt tttatctgag tactaacaac tttttatctg agtactaata
     1681 tccttttgta taataacaac caacctattt acgagttggt tgttaaaggt tattatttat
     1741 ttgtaagggg ggaagaaagg aatggatgaa aaaacggaat taacagtcaa atatcaaaat
     1801 gaattgaatt tagtaccgct gaaaaatttc aatgctaagc agatggattt attttttgca
     1861 ttatgcgctc gtatgaaaga tcgtggtttg aaaaaagtta gattttcttt cgaggaatta
     1921 aaagagttaa gtgattataa gatgactgct acaaaagcct ttgtcggtga tttagaaaag
     1981 ctctataaag atatgcttaa tcttacttac cgtactgaag atgaggattc tattcgctac
     2041 tttgttttgt ttactggttt tgaaatcaat aaaacaaaaa agtttgttga agtcagtgtt
     2101 aatccggacc tagaatatat tattaatggt ttaacagctg aatttagtag atttgaatta
     2161 tctgctttca cgtcgttgcg ttctacgtat gcaaaaactc tattccgact gcttatgcag
     2221 taccgttcta ctggttatta tgtagttcgt attgaagagt ttaggagctt aatggatatc
     2281 ccagaatact atcaaatggg taacattgat caaaaagtat taaatcctgc attacgagaa
     2341 ctaaaaaaat acttcaatga tcttaaagtc acaaaaataa aagcaaaaaa gggcaataaa
     2401 atcgccaaat tagaatttac tttttcaagc ctaacgtcag atttgccaa
//
LOCUS       DAZKNV010000138         2418 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000138 DAZKNV010000000
VERSION     DAZKNV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.144"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..1149
                     /locus_tag="ACG8M1_002832"
                     /pseudo
     CDS             5..1149
                     /locus_tag="ACG8M1_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            1320..1778
                     /locus_tag="ACG8M1_002833"
     CDS             1320..1778
                     /locus_tag="ACG8M1_002833"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFQ0423474.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1937..2407
                     /locus_tag="ACG8M1_002834"
     CDS             1937..2407
                     /locus_tag="ACG8M1_002834"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFQ0423475.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          810 a          454 c          455 g          699 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccaa aagatctagc cgatcagatc
      661 ggattttacc aaaatgctat cggagccgta cttggtcccc aagatagctg gttacttcag
      721 cgcggaatca agacactaag tgttcgtatg gaggaacatc aaaaaaatgc ttttgtggta
      781 gctgattttc tattttctca tccagcagta gaaaaggtct actatccagg attacccgat
      841 catgaactcc atggagttgc taagcagcag atgagcggct ttagcggaat gatttctttt
      901 actttaaaaa atgaagaatc tgctattcca tttgttgaat cactccaact atttacttta
      961 gcagaaagtt taggtggcgt agaaagttta gtggaaattc cttctgtcat gactcatgcg
     1021 tctattccaa aagaaaaacg agaagaggct ggcataaagg acggcttgat ccgtctttct
     1081 gtaggaattg agtatggtca ggatctcata aacgatttag ctcaggcatt tgacagaatc
     1141 aagaactaga agtcccaata aacgacttag cagaaaaatc taaaaaatat ttcagattgc
     1201 tacaccttgg aaacgataag tgttagaatc aagtagaaag acgtttttgt aaatttcact
     1261 aaataattct ttagtgaaaa gcatcaaaac gaatgaacaa acagatagga gtcttacaaa
     1321 tgagaatgaa tgtcgaaagt tttaatcttg accatacaaa agtcaaagca ccttatgtac
     1381 gtgtagctga tcgaaaaacg ggtgcgcatg gcgatgtcat cattaaatac gacgtccgct
     1441 ttaaacaacc aaataaagaa cacatggaca tgccaagtct acattcactt gagcacttga
     1501 ctgccgaact aatccgcaat cacgcagatt acatcgtaga ctggtctcca atgggatgcc
     1561 aaacaggctt ttacttgact gtattgaatc atgaaagcta cgaagacatt ttagatgttc
     1621 ttgaagcaac aatgaaagat gttcttgaag ctactgaagt acctgcaagc aatgaaacac
     1681 aatgtggctg ggctgccagc catacactag aaggtgcaca agctttggct cgtgaatttt
     1741 tagcaaaacg cgatgaatgg tctgaagtag aagcatagtt tctaaaagaa cgtaaagatg
     1801 agaagcaata tagctatctt atcttcgtat tttattaaat atttattgtc tgaaaagagt
     1861 tctaaacggg aaaacaaata gctagttttc agtttagcgc tctttttatt atataaaata
     1921 gaaaggagaa aactttatgt ctatttataa ttttgaaact actttagaag acggcactgt
     1981 ctattcattg aaaaaatatg caggcaaacc gataatcatt gttaacactg caacaaaatg
     2041 cggtctagca cctcaattta aacaattaga agaactttac caagcttatc agacacaagg
     2101 tctggttatc ttaggctttc cttccaatca atttaaacaa gagctagatt cagcgactga
     2161 agcagcagaa gcttgtaaaa ccacttatgg cgttaccttc cctatgcatc aattgattga
     2221 cgtaaatgga gaaaatacag atcctctttt tacttatctt aaaaatgaag ctcctggtac
     2281 tgtcactaaa gcaataaaat ggaattttac taaatttttg attgatagaa atggcaaagt
     2341 aatcgaacga tttgcaccac aaacttctcc attgaaaatg accgctgcaa ttgaatccgt
     2401 tctttaactt aataaaaa
//
LOCUS       DAZKNV010000139         2406 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000139 DAZKNV010000000
VERSION     DAZKNV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.145"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(101..708)
                     /locus_tag="ACG8M1_002835"
                     /pseudo
     CDS             complement(101..708)
                     /locus_tag="ACG8M1_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            1231..1905
                     /locus_tag="ACG8M1_002836"
                     /pseudo
     CDS             1231..1905
                     /locus_tag="ACG8M1_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            1898..2059
                     /locus_tag="ACG8M1_002837"
     CDS             1898..2059
                     /locus_tag="ACG8M1_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423476.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
BASE COUNT          861 a          366 c          401 g          778 t
ORIGIN      
        1 tatgaatata aatagagtgt atcttctttg ataaatgtca gaaaaagtgt gacaaataac
       61 catcagtaaa attacttgtc atactattga taaggagtat ttaattgaag agaatgatta
      121 ggagaaagga tctccgtact ttttatagta atcatagaat ccaagtttgt atagacgaat
      181 ctttttttct cttatttctt ctgtttcaaa atggactgct tgaagaatca agtctgtgaa
      241 ttctatagga gctgttccat tcgcagtaat caaattacga tctttcacag cttgttgttc
      301 tataaaatct tctttattct gataattttc cgattctaac caaggaaatt gcgcatttcc
      361 ggtgtgtttg taaccttgca ataatccgct ctgagctaaa taatcaactg ccccacaaat
      421 agcagctact ggtacgtctg tttttaacaa tttatcgatt atttgatata aatgatgatt
      481 ttttatgtcc catgaattgc caccgatcat aataaaaagg tcaacttttt caggtatttg
      541 ttcgattaag taatcgattt ttgtttttaa tcctccaatg gaagtgacct ctgattggat
      601 agaagcagtt ttgttttgcc atccctcttt ttggtttagt gtgctagtaa tataagcacc
      661 ttcccaatcg gcatattcct ctaatagaaa cgtaatcgca gttttcattt tcaagctctc
      721 ctttactatc tatgacaagg acaacagttt taacatacag acattcatta aatttggata
      781 gcgacagcga aaacaacaat tcttaagttt tagacagagt atacagacag tcaacttaat
      841 taaatacgaa ctaaataaaa atgacaggta atcatttttg tttaccagca ttataacatt
      901 ttgcatacat ggatgacaaa agaaccaatt cccacttgct tgagtacaat cttaaaagaa
      961 actggaaggc aaaaagtaat tatagaaacg aaaaataaat catatcgggc actcagacat
     1021 gaaaacaacc ctagaaatat ataactagtc caatgaaaaa aaagcgaatg ccgtagaaaa
     1081 caaggattct gcgtacattc atatctcatt ttgcgagcat atctgctatt actgtgacta
     1141 aatgttaata tggttaaaat gaccgttata ttttttatat aaatatcgta taattagtat
     1201 gaatatagaa gaaggaaaga aggtgcaatc ttggaaccta aagacaagta tttagattac
     1261 gctagggtca ataaagataa atttattgaa acaatcatca agggaaaaat ccctgatgat
     1321 gaaaaagatg cggtattcat ggctggaagc ccaggagcag gtaaaacaga ggttgcacta
     1381 ggtttagctt aaaattatga caaccatgtt gtgattgatg cggactattt tagagcacaa
     1441 tttccagaat acaatggaaa gaactcaagt gtttttcaga aagcttcttc ttggttagtt
     1501 gaacaatcat taaaatatgt actggaacat ggctattctt tcatactaga ggatactttt
     1561 gctatcctta gtgcagagaa aaatattatt cgagccctta aaaataactt tcgcgttacg
     1621 attttctatg tttaccaaga tcccaaagtt gcctgggatt tcactcgaaa acgtgaacta
     1681 gctgaaggac gtcatgtgcc aaaagaaatg tttatcaatg cgttttttaa gtccagagag
     1741 aatattgaaa aagtcaaaaa tagacatcct gaagtagtcc ttcacataat gattaaggat
     1801 tatcaaaacg acatttctga agtgcattat gcagcagata atattcaatt agtactacca
     1861 atacaatata cttcaaaaga gttggaggag gaattacatg actgagaaag aacaagtaca
     1921 acaaatcgtg aagaagtata ataaaagtat cgctgattta tcagaaaacg cctcagcgaa
     1981 agaatttaaa acagtaatga attacgtagc agatgaagca aatcgtaagc agcgaaaact
     2041 agttgggttg gataaataaa ttttttaaac catatccttg taaagttgag ttttttattt
     2101 taatgaatta agactattaa atagataatt attgtaactt aaaaaacaca gctaaaaatt
     2161 agttgtgttt tttattaggt ttacttttct ggtataaaag gaactagcta ctttttcaaa
     2221 atttctaaat cattcaatat gtagcgctta ctaaattatt cgccataaaa ttttataatt
     2281 ggatcactca ttgttttacc taagtcatat ttaagtaata accggtgttt ttacataaga
     2341 agacttcggg tattttttag tttgattagc tctgatatac ctataaagaa tatgctaagg
     2401 taagaa
//
LOCUS       DAZKNV010000140         2392 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000140 DAZKNV010000000
VERSION     DAZKNV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.146"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            230..>2392
                     /locus_tag="ACG8M1_002838"
     CDS             230..>2392
                     /locus_tag="ACG8M1_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HFQ0423477.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
BASE COUNT          949 a          357 c          461 g          625 t
ORIGIN      
        1 gaaagcaata agtaaaataa aatgaatata tgcgaaaaaa taatttacat taggaaaaac
       61 cttgtaaaaa cagttttttg gcatatttat tttttataaa tatttgtaaa ataactatca
      121 attttttagt taaaagattg gaaatgagtg ggggaggaat tgaagaaagg atttttgaga
      181 gatgatatag taggttttat ttttagttaa aataggggag atagaaaaaa tgaaaaagtg
      241 tagaaatatt attttatcaa tgttatttat tattactaat ataacatcac tgattcctgt
      301 tcatgtctat gcggatgcag gcagagatat cagcagtaat gtcacttcgt tgaccgtgga
      361 cccaacgaat attacagatg gaggaaacat aaaagtaaaa ttctcgtttg acgaaaaaaa
      421 acaaaatatc caaccaggtg attatctttg gatcaattgg ccaagtgaag gaaatattcg
      481 cggtgaagga ttccaaaaag aaatcccatt aatgattgaa aataaaaatg ttggaacttt
      541 aacggtcaga aaagattctg cgcaggttgt gtttaatgaa aatattaaaa acctagactc
      601 agtagaaggt tgggggcaat ttgagataca ggccagaaac gtaaccgata ccggtgaaga
      661 aaatacggga ccattcaccg tgacgagcgg tgataaaaca gctactgtaa atgtgacaaa
      721 gccagcttct ggttcttctt ctagcgtttt ttattataaa acaggagaca tgctacctga
      781 agatactaag cacattcgat ggtttttgaa tattaacaat aacggcactt atgttgaaca
      841 accagttaaa atcagtgatg aaatccaaag tggacaaaga ttagatccaa gtacgtttga
      901 aattaatcaa atacacttag gtgaacagaa ggtttataga ggagaagagg gaatccaaca
      961 atttttacaa gatttcccca gcgctacatt taatttttca gtaactgata attacattga
     1021 aataactata ccaaaaaact ttgtcaatct taggaaaata atggtgagtt ataagacgat
     1081 catagaaaac ccagaacaaa taaattttga gaatcattcg gaagcttggt ttaaagaatt
     1141 taataaacct gctgttgatg gagaaagttt caatcataca gttaaaaata tttcagcttc
     1201 tggtggagtc aacggtacag ttagaggcga attgaagatt ttcaaatata tcaatgacac
     1261 agagattggt atcccaaatg tgactttcga attaagacga gcagatgaac agcctattca
     1321 aggacagtct agtatcctgt tgacttcgaa tgaacaggga gaagctagta tcaaaggcct
     1381 gcaagtagga gactatgttg taaaagaaaa agaagcaccc aattggattg attttgatcc
     1441 actaagttca aatgaactca aattctccat aaacgaaaat gatacagagg gagtcagttt
     1501 acctatttat aacaagaaaa aggttacgaa catcacagca actaaaattt ggaacggtgg
     1561 aaccactcca agaccgagta tttattttaa attattcaga gcaagtacaa acaattggga
     1621 accagttcct gatgcagaaa caaaacgatt agacaatgga ataacttcag tgacttggga
     1681 agatatccaa cagtatgatg atagtggaaa cgaatatacg tttaaagtgc aagaagtaga
     1741 tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa attgaaaacg ggctagtcgt
     1801 tacaaatgag aataaagaag tcatttcagt ctcaggacaa aaaacatggg aagacaatga
     1861 gaaccaagac ggcaaacgac cgacgacgat cacagtaaat ctattagccg acggtcaacc
     1921 gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc tatcgtttca caaatctgcc
     1981 aaaatacaga gacgggcaag aaatcatcta tactgtaacg gaagacaacg tgcccgaata
     2041 cagtacgacg attgacgggt ataacatcaa aaacagttat acaccggaaa aaacaaatat
     2101 atctatacca ggtagccata taacaccgtg gaaaaatttt ccagagaaga cagagagaga
     2161 gaaaattaga aatctattct ctcaaaaatt gcaaatattt gctcatacag gagaatccag
     2221 cgaacaaaga agcaattata ttagtaagag agctgtacct aaacagataa caaataaatc
     2281 aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt tttgctgtaa tcattggttt
     2341 attgatagta actatctgtg ctgggatatt cttacaaaaa tataaaaaag tt
//
LOCUS       DAZKNV010000141         2271 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000141 DAZKNV010000000
VERSION     DAZKNV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.147"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            192..446
                     /locus_tag="ACG8M1_002839"
     CDS             192..446
                     /locus_tag="ACG8M1_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0423478.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            447..764
                     /locus_tag="ACG8M1_002840"
     CDS             447..764
                     /locus_tag="ACG8M1_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0423479.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1323..2258
                     /locus_tag="ACG8M1_002841"
     CDS             1323..2258
                     /locus_tag="ACG8M1_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423480.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          430 g          711 t
ORIGIN      
        1 ggatgttaac ggaagtgtat ggtgagtagt tcactcgtat tttgatatcg tttgtatatg
       61 ttttcagcgt tctaagtggc ttattttgtc caataataat atggagtgga atcccttaag
      121 aaacaccgtt ggcaattgtt gttataacat gttataattt attcatcaaa aactaaaagg
      181 agtgtgataa catgggaaaa gaactaaagg ttagaaagat cggcaatagc gtgggagtga
      241 tccttccaag ctctcttgga ttaaaaagcg gagacattat ccaagccaaa caagaaggca
      301 acttattcat attagatact actcaaatag caaaagaaca cgatcgcaaa ttgattgaag
      361 aaagtttcca agactttgag aaaggtttaa cagtttcaga aattgaaatg gtaaaagctt
      421 tcggaaaata cggctggagt gaatagatga aagagtacac gctagtttat tctaaaagtt
      481 ttcagaccag ccttgaaacg ataatagaag aatgggaaaa tgagcttgct ctttctccag
      541 ccagcataaa aagatttgta ggtgcgatcc agaaggcttt agaactaacc aaaaattttc
      601 caactatgca tgaggaagtt tccgaaatct atggaatgga tatcccaaca tatcggatcg
      661 tgatcggcaa aagctatgcc ttattttatc ggatcgacca tgaaaaaaaa gagatacttg
      721 taggacgtat tttccaatct aaacaaatga aactaggctt ttaacaataa ttaggaaaaa
      781 gtcgctcatc ctctacaggt gggtgattaa tgccgctcga tatggttgtt aaccgtcggt
      841 tactcgaaga ttgatatata agacttagta cctttttatt ttgctccatg ttatggccga
      901 aggtctaaag atacaatcat tagtctagag aaaaattaag aaccgtagga actacgggga
      961 tcgcttggtg aataagagac actgctatta gtgaaaaaat aagatatcaa gtacgctcta
     1021 ttcccaaaaa tttcgtgact ttactcatga gaggttcaag tagtatattt ttaatcaaaa
     1081 ttgacgtaac ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa
     1141 agaggaagtc caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata
     1201 tacatccctg ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga
     1261 atgggataaa atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga
     1321 tagtgaacat acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta
     1381 ctttcaaaag attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat
     1441 acaagtttaa ttttgttcaa tcttcagtat ctactgaaag tatctatttt tcaattcttt
     1501 ctgagagtag gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata
     1561 tatatacgtt ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg
     1621 aatatctcaa ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac
     1681 catatttgaa tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta
     1741 atcaaggaaa tatgaatatt acaagtaaca aaacgtcacg tgtgctattg gcgttgatgg
     1801 gttacggaat tctttataga gatgaccaaa atggccagat tctaataaat cgggctgggc
     1861 gttcattatt aatgaaatat agaaaattta taccggaaga ttttcaaaac ttacagttag
     1921 aaaacatgcg tttagaagat ttatttagat tagcagaaga tgataagtat agatttgaag
     1981 ttttgaaaat tcaaaagaat gaactattga ataagttata tcctgagaat gcgataaaag
     2041 cacattttgg tgatgctaat catatgtata gttggttcat tcctaaaaga tttagaggga
     2101 aaatcaatgc tggagatcaa gtgaaagtac tcaatcgaaa tagtacagat gtcgtaatga
     2161 taacagatat ctatgtagaa gatgaagata taatcaaata tatgaagcct gtgataaaac
     2221 ttgttaataa aaataaagga acccgtggtg ctagttaatt ttttcctaga g
//
LOCUS       DAZKNV010000142         2271 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000142 DAZKNV010000000
VERSION     DAZKNV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.148"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..794
                     /gene="wzy"
                     /locus_tag="ACG8M1_002842"
     CDS             <1..794
                     /gene="wzy"
                     /locus_tag="ACG8M1_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFQ0423481.1"
                     /translation="GSNFSKVITRFVFIIFALYSLLGIMSGDRGSWLYSSIILIWAYT
                     QYKGTFNYKKLIKWLILAVIGIYILNVITKARDGGGLSKLTLKDFTSVFDSDDSPLVD
                     SFFEMGGTMSIITFFLISGNGIYPFANTYLTSLLGSISTRMLSMFGIKFVLLADWFSQ
                     DYLGITWGTGFSMIAEAYVNGGYIGGIVYIFIIGIVIGKILSNSIDNQDIENHPMKMF
                     LAITTANIIMGFPRAASYLIVKNFVYGVLIILLINFFLQQFNKRL"
     gene            840..>2271
                     /locus_tag="ACG8M1_002843"
     CDS             840..>2271
                     /locus_tag="ACG8M1_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFQ0423482.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWARKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIIL"
BASE COUNT          733 a          309 c          397 g          832 t
ORIGIN      
        1 ttggtagcaa cttttcaaaa gtaataacga gatttgtttt tattattttt gctttatatt
       61 ctttattagg aattatgtca ggagacagag gaagttggtt gtatagctct attatactca
      121 tatgggcata cactcaatat aaaggaacct ttaattataa aaaattaata aagtggctta
      181 ttttagctgt tataggaata tatattctaa acgtaataac gaaagcacgt gatggtggag
      241 gactaagtaa acttacttta aaagatttta catctgtatt tgattcagat gattctcctt
      301 tagttgattc tttttttgaa atggggggga ctatgagtat tataactttt ttcctaataa
      361 gtggtaatgg aatatatccc tttgctaata cttatttgac ctcactctta ggctctatat
      421 caacaagaat gctatcaatg tttggaataa agtttgtttt attagctgat tggttttctc
      481 aggattattt aggaatcact tgggggactg gattctcaat gattgcagaa gcctatgtca
      541 atggtggata cattgggggt atagtctata tttttattat tggtatagtc atcggtaaaa
      601 tcctttctaa tagtatagac aaccaagata ttgaaaatca tcctatgaag atgtttttgg
      661 ctataactac agcaaatatt ataatgggtt ttcctagagc tgcttcatat ttaattgtga
      721 aaaattttgt gtatggtgtt ttaattatat tgttgataaa ctttttccta cagcaattta
      781 ataaacgtct ttaatattta agcttaataa aaagataaaa caagtcagga gttgcaaaaa
      841 tggaaagaac tgctcggctc aaaaaaaaca ctatttgggc tctggtgttt caaataactt
      901 ctattgtctg tggtatgatc ttgctacgtt tgatattaac aaagtacgga tccgaggtta
      961 atggaatgat tagctctatt aaccaatttc tacaaattat ttctttttta caattaggag
     1021 taggcgctgt aatgcaatca actctataca aaccactagc agaaaaggat aatttaatga
     1081 taagtcaaat cttagcttct ggagggaagt tttatcggca aattgcatat attctactag
     1141 tatacgtggg tttgttactt gcagtctatt atgttctcgt tcctaatgaa tttgggagat
     1201 catatacaat ggcaatgatt gcaacattaa gtattaattc atttgctcaa tattattttg
     1261 gtattgttaa tactttgtta ttaagtgctg accagaaaat ttatattacg tatattgcac
     1321 agacaatagc atttatttct aatacagttg catgtgcttt attaattagt ctgaacacag
     1381 agatccttat ggtaaaactt attactgcta taatttatct tgcttgtcca atatattata
     1441 gatggtatgt ggatcgaaac tataatataa agaggaatgt gtcatatgat aaggaaccga
     1501 tccctcaaaa atggaatggg gttgcacaac acgtagcttc tgttgtacta gatagtactg
     1561 atgttgtagt gttatctata ttttctaacc tgatatatgt atctatatat aatgtgtaca
     1621 atttagtaat atacggagta aaacagctat tcatggctat gacaaatggc gttcaggcct
     1681 tactagggga actttgggcc agaaaagaaa tagaagttct ttacaaaaca tttgcatggt
     1741 tcgaatggat tgtacatact ttgacagttt ttatttttgg ctgtaccggt atactaatcg
     1801 ttccatttat tcaagtatat acaagaggag taacagatgc taattataat caattatcat
     1861 tcgcagcttt acttgtaact gctaacgcac ttcactgtct gcgtacacct tatcatgtaa
     1921 tgataaaagc agctggtaaa tataaagaaa ctcaaaatag ttttataatt gcttctttgt
     1981 taaatttagg tttatcatta attttggtta aaccactagg gctagttgga gtagcattag
     2041 gatctctaat ttcaatcaca tatcatacac tttggagtgc aaattataat tcaaaatatt
     2101 tgcttaaatg gccgatgaaa aaattctata aacagttatt tgtaaacatc ttaactgtag
     2161 ttctttcttt tggggcgaca tcacaattga aaatgatgtc aatcacatat ttggattgga
     2221 ttgttctcgc aattaaatgt gcagttattg tatttatatg tataatccta g
//
LOCUS       DAZKNV010000143         2261 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000143 DAZKNV010000000
VERSION     DAZKNV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.149"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(365..1657)
                     /locus_tag="ACG8M1_002844"
     CDS             complement(365..1657)
                     /locus_tag="ACG8M1_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFQ0423483.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="ACG8M1_002845"
     CDS             complement(1931..2191)
                     /locus_tag="ACG8M1_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423484.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          746 a          430 c          344 g          741 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa g
//
LOCUS       DAZKNV010000144         2259 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000144 DAZKNV010000000
VERSION     DAZKNV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.150"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(148..>2259)
                     /locus_tag="ACG8M1_002846"
     CDS             complement(148..>2259)
                     /locus_tag="ACG8M1_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFQ0423485.1"
                     /translation="LEKIRKGAQEPKNKTFRRSHVPFRLNFLFFIIFTLFVALIARLG
                     YLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKANQAITYTRGTQVTA
                     KDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKRLSAKEKQLGNSEQY
                     SAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGVTDQELAVVAERASE
                     LPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLAKGYSRNDRVGQSYL
                     EKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSMNAEFQSKVEEILKR
                     NYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEITENALGTITSAFDP
                     GSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRSGQVALDAVKASELS
                     SNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFGLGTTTGIDLPNESP
                     GISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQYASTVANGGKRVQP
                     HLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGFHQVVHGTDPYTTAK
                     PLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEIAISVVLPNLLDEQD
                     HINLTIAKEIMDAYYDMFMAK"
BASE COUNT          574 a          505 c          411 g          769 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaa
//
LOCUS       DAZKNV010000145         2142 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000145 DAZKNV010000000
VERSION     DAZKNV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2142
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.151"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..1600)
                     /locus_tag="ACG8M1_002847"
     CDS             complement(53..1600)
                     /locus_tag="ACG8M1_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFQ0423486.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1702..2055)
                     /gene="tnpB"
                     /locus_tag="ACG8M1_002848"
     CDS             complement(1702..2055)
                     /gene="tnpB"
                     /locus_tag="ACG8M1_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFQ0423487.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          608 a          444 c          380 g          710 t
ORIGIN      
        1 tgtacgtcaa ataacccgac ctatagaata gaatcgggaa tgtttggcgt ttttagttac
       61 gagaaaaatg ttgttgtaca tccttgttcc aaggcaacag ttgatctaaa gtttctgctg
      121 aaagtacggg aagatttggt atcttatcaa atagaaactc tagatacttt acaggattca
      181 atccgttaag ttctgctgtt ttatatacac tcagaatgat tcctgaagtt cgtgctcctt
      241 caagacttgt ggaatgcaac caatttttcc gtcctatcac cagctctttg atatttcgct
      301 ccgcacgatt atttgtgagt tctaaacgac catcttcaaa aataggttca aaaccacttc
      361 gtagtttaca cgcatattga acggctgcat ccaacttgga ttttgcaaca ggatctatcg
      421 ttgccatcca ctcataaaaa gcaataaata atggacgcag ttcttgttgc cgacagctta
      481 atcgcttctc aggagaaaag tctttccatt tcttttctag gacaaaccat ttatccaatt
      541 gtttgactgc ttgagctgcg ggaatatccg tgtttttctt tccttttgga attgcttcga
      601 aaaatttccg ccgaacatgc gcgaaacaat agacaagtcg tacactttcc acggcattat
      661 acccgctata gccgtcacag tgtaaatacc ctgtaaactc cttgagaaaa gttttcggaa
      721 catctccagc acgactttcg tcgtggtgat aataaacgat gggatgctga ctgtcttttc
      781 ctgtacaaaa ctgccagtaa taggtatctg ttttggcact ttcaatcaca cgataacttg
      841 tttcatcccc gtgtagaatc tcttcttgat taagatagac tcttaatcgt tctcctaaag
      901 ggtctaacgc gttttgcact gctttaatat gccaattggt gatattatct ctcgaaatat
      961 ccaacccatg tgtttgtttc caatagttct cttgccgata ggcaggaact ttctgaccaa
     1021 atttcatccg gatcgtttcc gccactaaac tattggaacc taagctatta gaaatcaaag
     1081 gtttaggaac gatcgctttt ttaaaagaag aaagtccttc tttttcgcag cttttacaac
     1141 aataggtatg ttgataatgg gtgagacaat ccaacatagc ctgatggaaa cgaatttctt
     1201 ctcgtacttt tgtccgtccg atatctttca tctgtgaacc gcaatgttca caaaattgtt
     1261 cttccaaagg aaggagatgt tctttctctg ttataggtaa gtgtttgatt ttgtctgctt
     1321 tcgttcctac aactcgttga tgtcctttta ctggaataat ggtggcagct gcttctggaa
     1381 cacttacaga aatttcttca tcactaaaaa gattcaattg cccattcgtt tcctcaaaga
     1441 gagtctcttt agagcgtcca aataatttgt tggttaaata attgaccttt tcattcaata
     1501 gttggatttc agttgtaaga ttctgaatgg tttgttgttg tgcttgattg gttttatggg
     1561 cttcttgaag caactgaagc aacgtatctg tagtttccaa aatttttcac caccttgaat
     1621 cgaactgatt ttgttacaga ataccacaag aaacgcacaa gaaatagggg ttcaacacat
     1681 tttttgtgtt aaccccccag cttaaaaaac tccttttttt cctggcaaaa tagctcgagg
     1741 ttgatcgata cttaatcctt ctaacaacca tcgaacctgt tggttcgtta aggttcgaac
     1801 ttcgtctttc gtccgaggcc attttaactt gccgttttct atccgcttat aacagagaag
     1861 aaaaccatca ccgtcccaat agagaagttt gaaacggtct tgacggttcc cgcaaaataa
     1921 aaaaacggca tcttcgtaaa gctcgagttg atactcttgt tgaataagac tggcaagacc
     1981 atcaattcct tttcgcaaat ctgtttttcc gcacacaata taaatatgtt tggtttgaag
     2041 taaatcataa agcattggac aacagttctt tcaaaatagc ttgaagaata taattgttaa
     2101 taccgttata gatcaaaact tcagaaccat tctctctttt ga
//
LOCUS       DAZKNV010000146         2002 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000146 DAZKNV010000000
VERSION     DAZKNV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.154"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..377
                     /locus_tag="ACG8M1_002849"
     CDS             <1..377
                     /locus_tag="ACG8M1_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFQ0423488.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            425..1825
                     /locus_tag="ACG8M1_002850"
     CDS             425..1825
                     /locus_tag="ACG8M1_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFQ0423489.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
BASE COUNT          554 a          339 c          432 g          677 t
ORIGIN      
        1 aaaatgtttc cacagaggac ttctttaatt attgtcgatt agaggaaagt ggtgtaacag
       61 tcactagcgg tacagattta ccgctgttta ttactgatat tcctgaatcg attataagag
      121 cagtattccg tcgttttcct gaaggagaag aagtctggga gaaagaaaca agcttcacga
      181 caaccgagct gctgaaaagt tttacaagca acagcttcaa agtaaatggt ttatcggagt
      241 acggagaaat aaaagtaggg aaaagcgcca gcttagctgt tttcagcgag gacctctgta
      301 ctgatgactg gcaaaaagtg atggctgcgg aagttatcgc tacctatctt gatggtgact
      361 tagtttacaa gaaataatgc ttttcgatat aacgttataa aacgaattaa agagaggtta
      421 aaaaatggaa acaatgaaaa gaaaattcac cttcccacat agttatacat tgatttttat
      481 cttaattatt ttggctgcaa ttttaacttg gataattcct agtggtcagt ttgagacagt
      541 tgttgaaaac gtcgcaggta tggaaaaaac aacggttgtt ccgggaacct atcaccaaat
      601 cgataaggca gattatggac aaggtttttc ctctatacta atggcaccag ctgaagggat
      661 tatttcagct gttgaggttg ttgcttttgt tctcatcgtt ggtggtgcct tcgggattat
      721 cctaaaaacg ggagccatcg atcgagggct gtttacctta gcaaaagttc tgggagacaa
      781 ggggatctta gttattccga tgtcgatgat tctattcagc ttaggaggat caacctttgg
      841 catgagcgag gaagtcattc ccttatttgc ggtgtttatt tctctgatgt tttctcttgg
      901 ctatgattcc atgactgcga tcttgattct atttttaagt acacaagcgg gatatgttgg
      961 gtcgacgatt aatcccttca acgttttaat cgcacaggga gtagctggcg tttacggaaa
     1021 tcccctgctt tggtttcgga tgctatcctg gattgtcatt actgggattt caattgtttt
     1081 caccatgctt tatgctagca gagtcaaaaa gaatccactg tcctctattg tttatgagag
     1141 tgatttaaag gttaagcata agtttcaaaa ttttgacact gaaaaagagt tttcaacaca
     1201 agataaacta attatcgccg gttttatcgt aggtttagga atcatgattt ggggtatcat
     1261 ttccaaggga tggtatatgg ttgaaatttc tgcactattc ttaggattag gtctttttgc
     1321 tgggggcatc gctagatttt ctcaaaagga aattgctgaa gcttttgtcg aaggctgttc
     1381 agatttcgcc tatgctgctg taatcattgg gctagctaga ggagtcttgg taatcttgga
     1441 aggtggaatg attattgaca ctattctaaa cagcttggct aaccttttag gtggtcttcc
     1501 aaaattcctg ttcactacga ttctactcat ttctcaagta attgtttcct tttttgttcc
     1561 atcctcctca ggagctgcgg cattaacgat gccggttatg gcaccattgg gtgatctaat
     1621 gaatgtaagt cgtgatgttg ttgttctaag taaccagttt ggaaatggtt taatgaatat
     1681 tatctcccca actagtggtg tattactggc aggattagcc atcgcagaga ttaatttctc
     1741 taaatggttt aaggttggct tcaaaatatt tgccatctta acccttgttt ctgctgtttt
     1801 gttatacatt gctacactct tttagtctta atcatccatt aataggaggc aatagttatg
     1861 attaaaataa atcaattagc aggaatgaat atccactatt tattttattc tctcaaagaa
     1921 tttttcgctt atcaacagaa aattggtatt tcttctgttg aactttgggg aggtgctccg
     1981 cattttttca tagatgcttt ta
//
LOCUS       DAZKNV010000147         1983 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000147 DAZKNV010000000
VERSION     DAZKNV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.155"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            103..1947
                     /locus_tag="ACG8M1_002851"
     CDS             103..1947
                     /locus_tag="ACG8M1_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423490.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT          648 a          362 c          322 g          651 t
ORIGIN      
        1 attctatttc ctcatcttta tctcattttt tattataaat aattgacgtt agtttaaaaa
       61 acgtttaccc taacattaca agttttagaa aggaatacct ttatgtcttt ttttaataac
      121 atatataata aaaaagaatc tttttattta cgtataaagt ggagcataat cattatatta
      181 tcattgttat ttttaacagg aattgcttat ttcttttatt ttattttttc tcctgcggac
      241 agcaatcaaa tgaaagaaat aaaagattcg tgggttttct atacaaaaga tgatcctgat
      301 tttaagtttg acagcaagta cactcgtacg attcctaccg tggataaaga cgaaacattc
      361 attatggaaa cgacacttga aaaaccgttg gacgaagcaa atttactaat caaaggaaac
      421 catcaatgga ttactgtata tctaggcgaa aagattttat accaacggaa agattatcag
      481 gaagaaagca atcccggact ctcattggct gtgatagatt taccagcaaa ttatatcgga
      541 aaaaaattga cccttacagt ctcatctcct tatcagaact atgctggact gccaccgaaa
      601 gtttatctag gaacaactgg accattgatt agttttattt attcacaatc agtgccgcaa
      661 gtattgacga tgataatcgc tgtttttatc gctataggga cctttttcta tacgatctac
      721 ttgatgtata aacaaaaacg tcttgaatac tcacttattc tcttaagttg ctttgctttg
      781 gcattaggat ttgaagctgt atcagaagat attttaagtg gtattctttt tgaaccattc
      841 gttcattctt ttttatctca tttatttatt atcttaacgt cagctttcat catctgctac
      901 tattggagcc gaatgtttta ctataaaaaa tggtacggaa ttttttgtac gttccaactt
      961 ttgattttta tcggcgttct gctttatgca acttttactc ctgcagaact tcctgaatta
     1021 atgccgattg ctaatattgc tagtgttata agcactttag tcacttcact tgcatgcatt
     1081 ggcgaagcat ataagaataa ccgtttttat gtagcttgta caccttggat cgtcttggta
     1141 gccattatcc attgcttgat ttacatccaa acggcattag gtatctatca aacaacgatc
     1201 aattggtcta cgattttata tattatcatt ctaatcgtta ttatcagcta caatctaatc
     1261 gatcacatct taaataccga caaagatcgg agacaagtag atttcttaaa aatcaaaaat
     1321 gatttgttgg agcaacatta tgagcagctt cgacagcata tccaagaagt aaatacactt
     1381 cgcctggaat ttgtccaaga gatggagaat ctgcaagatt taatgcatac ggaccaaaca
     1441 aaagctaaaa actatgtgga aaagatatta gaagaagcaa aaaatttcga aatgctgtgt
     1501 tctttttgca accaccaggt gacaaatctt atcttagcgc gttaccagaa gttagctgcc
     1561 aaacggaata ttcagataac cttccaagca gatcttcccg aagaacttcc tatcaacgat
     1621 gacgatctgg ctcaactttt gatccacgct ttagagcatt cctttagaga aactcatgcc
     1681 atcgaaaatc cactgtatcg aaaaatttat ttgtcgatac acgaacaaga ggaacatttc
     1741 gtcatttgtt gcgaacatag tgcacattac gatacaaacc tatttagtcg aggcatcaca
     1801 gaagaattag atgatcagga acgttttgac ttaatgatga tgaaagacgt agcggatcgt
     1861 tacacaggaa cactaacgca ggaaaaagat actttcattg atcggatcac tgttcaactc
     1921 tctcgaaatt acccgaatcc tgtataaaaa atagcggaat ccatatatgt ggattccgct
     1981 att
//
LOCUS       DAZKNV010000148         1979 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000148 DAZKNV010000000
VERSION     DAZKNV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.156"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(346..528)
                     /locus_tag="ACG8M1_002852"
                     /pseudo
     CDS             complement(346..528)
                     /locus_tag="ACG8M1_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(728..1744)
                     /locus_tag="ACG8M1_002853"
     CDS             complement(728..1744)
                     /locus_tag="ACG8M1_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0423491.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          559 a          459 c          308 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat aatcgcttat
      661 cgtaaatcca cgtcactaaa cattgacgta aatttactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DAZKNV010000149         1916 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000149 DAZKNV010000000
VERSION     DAZKNV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.157"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..398
                     /locus_tag="ACG8M1_002854"
     CDS             6..398
                     /locus_tag="ACG8M1_002854"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0423492.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            399..1838
                     /locus_tag="ACG8M1_002855"
                     /note="aph(2'')-Ia"
     CDS             399..1838
                     /locus_tag="ACG8M1_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFQ0423493.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRAYKD"
BASE COUNT          805 a          138 c          327 g          646 t
ORIGIN      
        1 agtttatgga agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag
       61 gatttcttaa tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag
      121 gatttgcata ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact
      181 caataggaat gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta
      241 ttaaggaata ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta
      301 atcctagagc ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa
      361 tagtatatgt atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa
      421 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
      481 aaagagtatt agaattttat ggtggtagag ataaaaaata tacattagaa tcattaaaaa
      541 aacattatac agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg
      601 ttcctattgg atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt
      661 atccaaaaac tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt
      721 ggagtaaagg aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa
      781 gaaatgctaa tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat
      841 accaaaaatc tggttttaga attattgaag atttgccaga acatgaatta cacgagggca
      901 aaaaagaaga ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg
      961 caatgaaata tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa
     1021 tcggtagtgg ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa
     1081 aatttagtac taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa
     1141 atacaaattt agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg
     1201 aattatctat actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt
     1261 ctactatgtc agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac
     1321 aaatgcacgg tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg
     1381 tattagaaga gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa
     1441 aagattatat agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa
     1501 agtgtttatg ccataatgat tttagttgta atcatctatt gttagatggc aataatagat
     1561 taactggaat aattgatttt ggagattctg gaattataga tgaatattgt gattttatat
     1621 acttacttga agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa
     1681 tgtatggaaa tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt
     1741 atcctattga aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg
     1801 gtagaaaaga aatttataaa agggcttata aagattgatt atataatata tgaaaagcta
     1861 ttataaaaga cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagt
//
LOCUS       DAZKNV010000150         1906 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000150 DAZKNV010000000
VERSION     DAZKNV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.158"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(113..238)
                     /locus_tag="ACG8M1_002856"
     CDS             complement(113..238)
                     /locus_tag="ACG8M1_002856"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423494.1"
                     /translation="MHLHRISALAVQIGRYHHSETRAVMVTRCCLLALVIAAANA"
     gene            628..1806
                     /locus_tag="ACG8M1_002857"
     CDS             628..1806
                     /locus_tag="ACG8M1_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFQ0423495.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAV
                     YQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIE
                     SFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE
                     "
BASE COUNT          685 a          336 c          345 g          540 t
ORIGIN      
        1 tatccataaa actaatataa agcttggtac gattctgttt gtaagacata cgaatagtat
       61 cagaggtagg agccaagctg cctgatatta aattatcgat aaagtagaaa ggttaagcat
      121 tagccgctgc aataactaat gctaggagac agcaacgtgt aaccattacc gcacgtgttt
      181 ctgaatggtg gtagcgaccg atttgaacgg ctagggcgga aatacggtgc aaatgcacgg
      241 tggtttcatg caatgcttac agggcgtatt ttgtaagggt atgtaacgga gataattccg
      301 acggtaatgg atgtgagagg ccaagccgac gctgacggta gggcaaacaa acatagttgc
      361 actctagcga tcgttattta tttttaacgg tcaaactagg gtacaactat gcttaaaaca
      421 cttcgcctca acttctggta gcaaaagtga ttttgaaagt caaaatattt tttatgagtt
      481 atttacaatt ctaaaaaaca agtgtattaa tctactaatt gagagtataa aatattttgt
      541 gtaaatgaaa aaatccatac aaaaaaggaa gtcccttctg tagaataaag ttaacgacaa
      601 ccaattcaca gaaaagagga cttccctatg aatgatttta ctacagaaat tgtgcaaact
      661 ctagtcacta aaggcgattt aaatgaatta ttccgttcgc acttagaaaa agcgataaac
      721 acactcctac ggactgaatt aacggctttt ttagattacg aaaaatatga tcgcactggt
      781 tttaattcag gtaattcgag aaacggttct tactttcgat caatcaaaac cgaatatggt
      841 gaattaacat tggaaatacc tagagatcgt aatggtgagt ttaaacaaca aactttacca
      901 gcctacaaaa gaacaaacga tacattggaa accactatta tccatttatt cgaaaaaggt
      961 gttacgatgt ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca
     1021 caaaccatgt ccaacatgac taaagttctg actgaagaag taaatgcctt taaatccaga
     1081 gccttaaatg ataagtatgt cgctattttt atggacgcta cttacattcc actaaaacgt
     1141 caaaccgtat ccaaagaagc gatttatatt gccattggta tacgagaaga cggcactaaa
     1201 gaagtactga gttatgcgat tgctccaact gaatcaacat acgtttggaa tgagctgcta
     1261 caggatatta actccagagg agttcaagaa gtcttgcttt ttattacgga cggcttaaaa
     1321 ggcatgaaag atactatcca tcaaatttat cctaaagcaa aatatcagca ttgttgtatc
     1381 catgtatctc gtaacatcgc tcataaagta cgtgtcaaag accgaaaaga aatctgtgat
     1441 gactttaagg ctgtttatca agctaactca aaagaagaag cgaatacctt cttatccggc
     1501 atgattgaga aatggaagaa aaactatcct aaagtgacgc agtcactcat agaaaaccaa
     1561 gacttattaa ctttttatga ttttccacct agcattcgta gaaccattta ctcaaccaat
     1621 ctaatcgagt ctttcaataa gcaaattaaa agatacagcc gtagaaaaga gcagtttcaa
     1681 aatgaagaat cactagaacg ctttctagtc agcatttttg atacatacaa tcaaaaattt
     1741 ctaaacagaa gccataaagg ttttcaacag gtaaccgata cattagtttc aatgtttact
     1801 gagtaactaa ttattttgca ggaggacaat ttatttacac aaaattattg acgctcccaa
     1861 ttaggactca attgttcata gatgagcatt tgtaattaag ttatat
//
LOCUS       DAZKNV010000151         1842 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000151 DAZKNV010000000
VERSION     DAZKNV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.159"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            206..403
                     /locus_tag="ACG8M1_002858"
     CDS             206..403
                     /locus_tag="ACG8M1_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423496.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            509..991
                     /locus_tag="ACG8M1_002859"
     CDS             509..991
                     /locus_tag="ACG8M1_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423497.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1049..1645)
                     /locus_tag="ACG8M1_002860"
     CDS             complement(1049..1645)
                     /locus_tag="ACG8M1_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0423498.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT          572 a          275 c          367 g          628 t
ORIGIN      
        1 taattagttt ttaaggaata tgttttaatt ttttgaaaaa aattcttcta aatacaacag
       61 ctgttttaat tgtgaaaacg aaaacagtac gctataatgc ctgtaaggtt gatttttaac
      121 tgtaaataaa aatcaatgag ttaaatctcc aaagaaatag cagtggtaat gtggagaaaa
      181 gttccagcag tttaggagga ttttgatgac ggaagaaatg attaatttag gagaacaata
      241 tgcatgcaaa ccaattggtt ttacaaaaac ggtcattggt gaagttgtat caaaaatgac
      301 aaactgcgcc gtggtcaaag ttgcccaatg tgctgcagag gaccaagaat tattagatga
      361 aaaagcaagc atggttgttg caaaatatga tacatttgaa taaagaaaac aattggacgt
      421 gcggcgtgct gcaagtccaa tttctttgag aaggtaaatc agtattcttt tcctattttc
      481 tggagaagaa aaagcgaggc gagttgtcat ggtaacattc tttacggttc tattgttttt
      541 attcgttgtt gtgatgtttt tatttctttg gctggttcga aaagaaatta tttatcggac
      601 tgtgcgaaat cgatgggtct acttggtgat acccttctta gtgtcactag tcatttggta
      661 tacactcatc agtcatccta cagcagatga attggcaaaa gggatcttgt cagcaatgat
      721 ttttattagt tttttgttgg acagtagagg aatcacagaa gaaggacttg ttttgaatag
      781 ctttgacaaa aaaggtgttc ctttttctga gatcaataaa attgtattat atcagccaaa
      841 aggttctaaa atcgtaaaaa tgaatttttt ccgaaacgga tggcgaggac cgatgctgaa
      901 attttctgca tcattagaag aattagttcc atttttgtcc caacgcttaa acgatgaggc
      961 agagattgat attatgattg atccagaata aaaacagagg ttgcgacaag atgtttgtca
     1021 caacctctgt tttttatttc aaataaaatt atccaaatac gcggaagcga tcggcatcgt
     1081 tcatgtattc tttttcccca gccggtgttt ctggtgaacc gaatactaat tgcgaacgta
     1141 gtttccagtt tgaagggata ttccattctt ttgcaactgc ttcgtcaata actgggttgt
     1201 aatgttgcaa gtttgcgccc aatcctttat caactaatgc tacccaagta ttagctgttg
     1261 cgattccgtt tgattgttct gaccaatctg ggaagttgtc tgcatataat tcaaattgtt
     1321 cttgtagacc ttttaccacg tcagtatctt tgaagaataa tactgtacca taaccatttt
     1381 tgaaaccagc taatttgttt tgtgtatttg ggaaagcttc tgctggagtc aatgggcgaa
     1441 gtgcttcttc agtgatttcc caaagttttt catgtgcatc tccgaaaagg ataactgcgc
     1501 gtgttgattg agcattgaaa gcagttgggc tttctttaat tgcttctttg atcaaagttg
     1561 ttaattcttc attagaaagt gaaacattac gtcctagatg atagattgaa cggcggtttt
     1621 tcaaagtgtc agtaaaagtt gtcataataa aatttctcct ttgatttgcg ttttgcattt
     1681 ttttaattga ttacgaaatg aagtatagca ccttacaaaa agtaagtaaa cagatatgct
     1741 cacaaaaaat aagcgaagtt caaaaaacaa ttttaataag aaaaatcgtt atgtaaggat
     1801 tttcttagtt atcgctttca ttgttgtgtt ttaggaattt tt
//
LOCUS       DAZKNV010000152         1834 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000152 DAZKNV010000000
VERSION     DAZKNV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.160"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..376)
                     /gene="relB"
                     /locus_tag="ACG8M1_002861"
     CDS             complement(53..376)
                     /gene="relB"
                     /locus_tag="ACG8M1_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFQ0423499.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            complement(719..1165)
                     /locus_tag="ACG8M1_002862"
     CDS             complement(719..1165)
                     /locus_tag="ACG8M1_002862"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFQ0423500.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            complement(1146..1742)
                     /locus_tag="ACG8M1_002863"
     CDS             complement(1146..1742)
                     /locus_tag="ACG8M1_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFQ0423501.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
BASE COUNT          569 a          331 c          242 g          692 t
ORIGIN      
        1 cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat ctctaccaat
       61 acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta aacggcaggt
      121 cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt ttcccacttc
      181 ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct tctagttgtt
      241 ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca gccatataag
      301 aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta taattgcctc
      361 tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt gctaaaaaac
      421 tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta ttatacatta
      481 aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa agcaacacta
      541 gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa gaagcctata
      601 ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac ttataataga
      661 acttagtctt atatagaagg catagctcac attagcttat ttgtcctata aaaataaatt
      721 acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat ttttctttat
      781 cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac gcgatacagt
      841 tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa tgtaaataag
      901 gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata ccttttgcaa
      961 gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt tttgagaagc
     1021 aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta ctaacttttc
     1081 ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt tgattttctt
     1141 cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc taatggaaat
     1201 ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata tatttgtcct
     1261 gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc aaataaatga
     1321 atctttacaa aattactttt tgaattggct aaaactttat tttgattctt atccaatact
     1381 tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca cttatcttta
     1441 taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg atgagatctt
     1501 ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt agtatatact
     1561 ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca tgtaataatc
     1621 ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa attagctaat
     1681 acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa tgttggattc
     1741 ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg aaaaatcgaa
     1801 aaaaactcat tttgtgtcaa gttatctgta atat
//
LOCUS       DAZKNV010000153         1775 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000153 DAZKNV010000000
VERSION     DAZKNV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.161"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            321..677
                     /locus_tag="ACG8M1_002864"
     CDS             321..677
                     /locus_tag="ACG8M1_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0423502.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            687..1586
                     /locus_tag="ACG8M1_002865"
     CDS             687..1586
                     /locus_tag="ACG8M1_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0423503.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT          589 a          301 c          362 g          523 t
ORIGIN      
        1 gtttactcta ccgaagagtt gttaataatc cgtgaacaaa aagtaattct ttttccaata
       61 gttgttaaag gttttttatt ttttatagta ttttttgtta tttaagaaag gaataaggtt
      121 aaacaaataa caggttgctt tttgggtctt tttccgttca agaaactgaa cgaagaaaag
      181 ggaaagttgt ctcttttgtg ataagagaaa tcataataaa cgaatgactt actttccaat
      241 aaattgagaa cagtcagaac cagacaaatt agttgcatct gatgaataaa gtgattattc
      301 tatgacatga ggtgatacag atgaaattag aagtgacaaa agaagcacaa gaagtattga
      361 agaataaatt agaagcagac gatcaacttt tattagatat cgaaaacggt gacggtccat
      421 ttgcagaaag ccaagtcagt tgccaattgg atacggcatt tcgattgatc attgtcaaaa
      481 aagatacaca aacagatcta agtctttatt ctgtagtggc tgatacacca gttggaccaa
      541 tcaaaatcaa agacagtgca atactttaca tggatgatcc atccacactt gctttagaac
      601 caacttataa tagtttacaa ttaaaaggac caagcggctt gagaaaaggc aacttgcaag
      661 ttgttcgaaa agactagagg gataaaatgg gaaaattggc gatcatcagc gacctacatg
      721 tggacatcaa taaattcggc gaatcagagc tgatgcagct ttggcaagtt ttgcaaaagc
      781 acaagatcac tcggcttcat ctagccggag atacggctaa taaagtagac cgttgcctag
      841 ctgttgtcga atttttcgtc aataaaggat tatctacgac atttcatttc ggcaatcacg
      901 agttggcaga tgtgcccaat gaacagatga tggaccattt tccagaccca cattttttaa
      961 atgaacggta tattgcttta aatgagcaga ccgttctttt agggatgaat ggctggtacg
     1021 actatcagtt ttccgaattg aaagattacg aggcaatcgt acgaatgaag cgtttgtatt
     1081 ggtatgatcg gttcatccag cgtgggaaaa cagatctcga ggtcaatgca gaaatgcttg
     1141 cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa acttgaggtg attttatcca
     1201 ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc tgctccttat gagcgttgga
     1261 acaaattaaa tgcattttta ggatcagaat cattcggaga attacttgac cgttattcaa
     1321 atatcaaaca agtagttttt ggccatacgc atcgtcgctt tgaagataaa tccatcggtc
     1381 acacgattta cagctgcaga ccttttggtt attattatga atggcagctg acccgagatt
     1441 ttgtcttgaa agaacagttg ctagacagct atgatcctat gaaattacgt gtcctcttgc
     1501 gtgcccatca cccagctttt caggcctatc aaacacaaca tttgcaagag gaatttgaac
     1561 aagcgatgac aatcgttccg tattgagaca gcattagtaa tgtgtaaaag aaaatacctt
     1621 gtaaaacata aggataagta agagcagtag atccatttat cgtggatatg ctgctttttt
     1681 tgcggaaaat aatcagcgaa tgtttatttg atcggatgat ttgtaactcg cagagtacta
     1741 gatgcaagcg tgtattcttt ttttgaacga taatc
//
LOCUS       DAZKNV010000154         1742 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000154 DAZKNV010000000
VERSION     DAZKNV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.162"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..944)
                     /locus_tag="ACG8M1_002866"
     CDS             complement(<1..944)
                     /locus_tag="ACG8M1_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFQ0423504.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAF"
     gene            1506..>1742
                     /locus_tag="ACG8M1_002867"
     rRNA            1506..>1742
                     /locus_tag="ACG8M1_002867"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          547 a          311 c          331 g          553 t
ORIGIN      
        1 taaaatgctt cttgtacata gctcaaaaat atttcgattg gtgttctgta attcaatgat
       61 tttcttggaa tatgattacg ttgattgctg acactggaaa taaatgtctg attcactttt
      121 ctaaaatcca ttgatttcgg cagtccatta cgacgcagaa tcccgttaga attctcgttt
      181 aatgggcgtt gagaaggtgt tccagggtcc gcaaaatata tatcaatatc atgttggtta
      241 ctaatggctt tccagttaga aaattctttt ccacagtcaa acgtaataga tttaaagaag
      301 tttttaggga agcgagaaaa ccattgatta agggcagttt caatatctaa tgccttacgg
      361 ccgttgggtt taatcgtgat aatgacttta gataatcttt caactaaagt aatgacggca
      421 cttttatgat gaatgccaac gatcgtatca ccttcaaggt gaccaaactc agaattgaaa
      481 tcaggataat tatcaggtcg atcatggatt gagcgctgat actgttgttt tccccgtttt
      541 tcctgatggc cattgggttt tcttttacct ttcatcggta gtgtgtcaat atcaaatatt
      601 cctttagaaa ataaacgata aagtgttctc ataccgcatg aaacaggcct ttcttttcgc
      661 ccgataatga cgtcaggcgt ccaaccaaga gtgactttct ctttaatgta atctacttca
      721 tgagcaggta attgaatgac ttttctacca cattttttct tattttcttt atactggtgc
      781 caataatcaa gagcagtctt gccttgcttg aacttattga ctacattata aatagtttgt
      841 atagcacgtc ccattcggtt agcgatttca accggcttat tatgttgaag ataatatgat
      901 tctatcattg tcagttcgtc tatggtaaga tgtttgtagg tcatttatgg ttacactcct
      961 ttgttttctt tcgtcggaaa tacaatttga gtgtaccata aatgcctttt tatttttcta
     1021 acttaatttt acaattcgcg atatattaaa caacgttgtc gcgcttcatt gaaacatttt
     1081 atgaaaattc caaaaaagag ttgacacatg tttttagacg tgataagata actaagtcgt
     1141 taaaaagaac cacttgcgaa gcttgattct atcgaaaaaa aacttcaaaa aagttcttga
     1201 caaataacaa acgataagtt atgataaatg agttgctgaa agatttcgaa aaacgaaatc
     1261 gaaaaaaact tttaaaaaag agttgacaat cgcttgtctc tctgatatga tataaaagtt
     1321 gctacggcag ccaaaaacga atcgggaaac actcccgatg aagtagatct ttgaaaactg
     1381 aacaaagtaa gacaaaccaa atgtgtaggg cgtcttgatt caattcaaga caataaacat
     1441 ttttaacaag caagcaatat gctagcaaac aaattgagct taacaatcgc aagattgttc
     1501 gaacttttta tgagagtttg atcctggctc aggacgaacg ctggcggcgt gcctaataca
     1561 tgcaagtcga acgcttcttt ttccaccgga gcttgctcca ccggaaaaag aggagtggcg
     1621 aacgggtgag taacacgtgg gtaacctgcc catcagaagg ggataacact tggaaacagg
     1681 tgctaatacc gtataacaat cgaaaccgca tggttttgat ttgaaaggcg ctttcgggtg
     1741 tc
//
LOCUS       DAZKNV010000155         1642 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000155 DAZKNV010000000
VERSION     DAZKNV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.163"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..403
                     /locus_tag="ACG8M1_002868"
     CDS             5..403
                     /locus_tag="ACG8M1_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFQ0423505.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="ACG8M1_002869"
     CDS             387..1082
                     /locus_tag="ACG8M1_002869"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFQ0423506.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
BASE COUNT          623 a          238 c          323 g          458 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat atttttagtc ttttttaaaa
     1381 taacttttca gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa
     1441 aaaataggga agcatgaaag aatctactta atagcgcatt gattcatgtg atagaaataa
     1501 aaaacttttt taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca
     1561 aataaaaaaa ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga
     1621 atttccaaaa atcacttctc aa
//
LOCUS       DAZKNV010000156         1604 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000156 DAZKNV010000000
VERSION     DAZKNV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.164"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..446)
                     /locus_tag="ACG8M1_002870"
     CDS             complement(<1..446)
                     /locus_tag="ACG8M1_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0423507.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSL"
     gene            complement(443..1096)
                     /locus_tag="ACG8M1_002871"
     CDS             complement(443..1096)
                     /locus_tag="ACG8M1_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0423508.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1384..>1604
                     /locus_tag="ACG8M1_002872"
     CDS             1384..>1604
                     /locus_tag="ACG8M1_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0423509.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEK"
BASE COUNT          518 a          270 c          175 g          641 t
ORIGIN      
        1 aataaagaat atggtaaaaa tttaaggctt aaatctttcg catctttttg catatcagct
       61 gtagaaacaa attgtagatt tgttttttta ccatcattaa gctttatttc tctttcttca
      121 attatcaaag aattactatc actttctaaa ttaacattta tattatcttt gatttgtatt
      181 tcattcttat tatttttttc ttttatgaat acttttattt cactactctt ggaataaaac
      241 tccaaagttt gttctatata ttttatttct tttccattca tattactaga aatttcattt
      301 gccatattat gaatcttttc ttttctcgtc tccaaatatg ttttaggaaa gataaaaaaa
      361 attaatgaat gaactaatat aattattatt ccaagaacag aaaatatttg tatgaacatt
      421 tttggaaata tctttaattt tttcattttc tctccaattt atatcctaca tttcttatag
      481 tagttataca gtctaattgt aatttttttc taagttcttt tatatataca tctattactc
      541 gatcataagg agtttcttcg ctatctttcc atacataatc aataatttgc attcttgtta
      601 acacttgtcc attattatcc aataaacatt ttaatacttc tagttctttt gcatttacat
      661 ctatttcttc accatttatt ttagctgtat agctattaaa attaaccgat agatccttat
      721 attcaaactt ctctaaatgt ccataattct tcttaattaa agaatctatt ctagctttta
      781 agaccggcaa tgaaaatggc ttttctacat atccgtctac taaattagta aatgcatcaa
      841 ttttatattc ttcatcacta aatgcagtca agattagaat tggtaaattg cttttctttc
      901 taatttcttt caacacttct aaaccattta taaaaggtat ctgaatgtct aagataacca
      961 aatttatatc gctattaaat tttgacaagg cttctcttcc atctttagct tgaataacag
     1021 tatatccaaa ttctgaaaga tattcactta ttccctctct tatcatatta tcatcttcaa
     1081 cagttaatat tttcatatat acctccactt aagcctatac actagatatt atacagcata
     1141 ttatggctct ataatatcta gtgttggtga caccttctgt tgccaatact ttttcttttt
     1201 tctaataaat gcaaacagac accttgaaat cctttagaat aaagggttct ataatatttt
     1261 gtgttgttgg aaaatcgaag gcgattttct actaacactt tttcttcgtt tcaactcaaa
     1321 aagagactca cttttggtaa aatttagtcg accaaaacat caccctacca aaggagtcgc
     1381 tctatggata atcatactag aaaattactc ggattaacag ataaacattt attttttgat
     1441 gaagaatggc tgattgaaaa agaatataaa ggcgttcaag cgcagtttat taaagggaga
     1501 ttggatgact caccttccca ttgtgaacac tgtggatcga ttcgtattat ccgcaacggt
     1561 tcctatacga cacgtactca gatattgaaa gtcaaagaaa agtt
//
LOCUS       DAZKNV010000157         1569 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000157 DAZKNV010000000
VERSION     DAZKNV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.165"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            56..1522
                     /locus_tag="ACG8M1_002873"
     CDS             56..1522
                     /locus_tag="ACG8M1_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFQ0423510.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          434 a          291 c          331 g          513 t
ORIGIN      
        1 tttcggtaaa gatgtataat attttctgaa aatttaaaga attggggtat agattatgga
       61 aaaacagcaa gacaagggct tcttcgggca gccgaaggga ttgtcaactt tgttcttcac
      121 tgagatgtgg gaacgattta gttattacgg tatgcgtgca ttacttatct attatatgta
      181 cgatacagtt gccaacgggg gacttggatt accacgagca acagcattag ctatcatgtc
      241 gatctacgga tctttgatct acatgtctag tatcgtcggc ggatgggtat ctgaccgagt
      301 gttaggagca aaacgcactg tattcttcgg tggagttttc attatgcttg gccacatcgt
      361 cttggcttta ccatttggtg taagtacatt gtttgtttcg atggcattga ttattatcgg
      421 aaccgccttt ttgaaaccaa atgtttctgg catggtcgga catctttatt caaagactga
      481 cttgcgaaga gatgcaggat tttcgatttt ttacatgggt gtcaacttag gggcattatt
      541 agcaccacta atcgttggta caatcggtca agaatataac tatcatttag ggttctcttt
      601 agctgctatt gggatgttct ttggattatt acaatacatc atccaaggac gcaagacatt
      661 agacggagtg ggtacaacac cgccgaatcc tttgacaact gaagaacgta aaggattcat
      721 ccgtaacttg atcatcgcac ttgttgttat cgctgcagta ttcggcgggg cacaactaac
      781 tggtcatctg acaattgact tttttgtcaa tacaatcagt gtattgggga ttatcttacc
      841 gttgtattac tttatcaaaa tgctgacttc aaaagatgta actgctgaag aaaaaccaag
      901 agtatgggct tatatcccat tattccttgc agcaatcatt ttctggtcat tacaagaaca
      961 aggttcatct atcttagctt tatttgctag tgaacgtaca caatctacgc tatttggtgt
     1021 aacgatccaa gcaagctggt atcaatcatt gaatccaatt ttcatcttta ttctgacacc
     1081 agtattcgta acgatgtgga cgaaacttgg tgaacgtcaa ccatctacag tagtgaaatt
     1141 ctctcttgga cttttatttg caggattatc gtacttgcta ttgatgttgc cgggtatgct
     1201 ttatggtaca agtggaaaag taagtccatt gtggttgttg ggaagtttct tcatcgtggt
     1261 tattgctgaa ttgtgtcttt caccagttgg tttgtctgtg acaacaaaat tagcaccacg
     1321 agcatttgaa tcacaaacaa tcgctatttg gttcttagct gatgcttctt cacaagcaat
     1381 caatgcacaa attgcacgct tctacacacc gggaacagaa tctgcttact tcggtattat
     1441 cggtgcagta gcaatcgtcg gtggtatctt gctatttact gtgaaagaac caatcaaaaa
     1501 actaatgggc tctattcatt aatcaatgaa cataaaaaca ggaattgctt atttgcagca
     1561 gttcctgtt
//
LOCUS       DAZKNV010000158         1536 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000158 DAZKNV010000000
VERSION     DAZKNV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.166"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>1536)
                     /locus_tag="ACG8M1_002874"
     rRNA            complement(<1..>1536)
                     /locus_tag="ACG8M1_002874"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          321 a          476 c          337 g          402 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccag
//
LOCUS       DAZKNV010000159         1519 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000159 DAZKNV010000000
VERSION     DAZKNV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.167"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            79..>1519
                     /locus_tag="ACG8M1_002875"
     CDS             79..>1519
                     /locus_tag="ACG8M1_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFQ0423511.1"
                     /translation="MKKSRLEYSLINSSISMFIYILRIVIQFVGRSFFIYFLGAKYLG
                     LNGLFTNILSFLSLAELGIGSSIIYSLYKPLAQKDESKVKALMNLYKKTYEFIGIFIG
                     IVGVLIIPLLPLFIKNSTDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYLVAI
                     NDFAFLFFMNIVQVIALYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEKDVV
                     SLDKQTKDEVKKNVIGNMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVTSVQ
                     NLCKQITNSITASVGNFAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPFISL
                     WVGAKYMLPMSTTILIVLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLLLSL
                     LLLIVFDMGINGVLIGTIGSSLGFVIWYEAFIIYKTVFEKRFIHFFLTFWRSFIELII
                     SAIVVFLLNEYLANGGSTFLQFITKTLITI"
BASE COUNT          509 a          183 c          239 g          588 t
ORIGIN      
        1 ctgcgtataa aataccggtt aaatatcagt ataagaaagt aaaggctgtt aatcaatgct
       61 ttagttagga tgaattagat gaaaaaaagc aggttagagt attctttaat aaattcttct
      121 atatcaatgt ttatatatat tttaaggata gtaatacaat ttgtaggtag aagttttttt
      181 atttatttct taggagcgaa atatttagga ttaaatggtt tatttacaaa tatacttagt
      241 ttcttgtcgt tggctgaact aggcataggc tcttctatta tttattccct atacaaacca
      301 ttagcccaaa aggatgaaag taaagtaaag gctttaatga atttgtataa gaagacatat
      361 gaatttattg gtatttttat cggcatagta ggagtattga ttattccgct gttacctcta
      421 tttattaaaa atagcacaga cataccacat atgtatcgat attatgtatt atttttatta
      481 aattcagttc ttagttattt tttcacgtat aaaagatcac ttgcaatagc agatcaaaaa
      541 aattatctgg ttgcgattaa tgattttgcc tttttattct ttatgaacat tgtacaagta
      601 attgctttgt acttttattc taattttact ctatttctaa tagtgcagat tttgtttact
      661 ctattttcta atataaatat ttccagaaca gttgacaaga gatattcata tttaaaagag
      721 aaagatgtag tttctctaga taagcaaaca aaagatgaag taaagaaaaa tgtcataggt
      781 aatatgtcct caaaaatagg cggggttatt gtaatgggga cagataatat attaatttct
      841 acatttgtta atttaacagc tgtaggaatt tattctaact attcattgat tgtcacaagt
      901 gtgcaaaatt tatgtaagca aattactaat tctatcacgg caagtgtagg aaattttgct
      961 gtatcaaata aaaaaaagga ttcatttgag ctatttaaaa aacatttttt tatcaaccac
     1021 tcactaatct ttttttcttc tatattgtta ttgactttaa tgaatccctt cattagcttg
     1081 tgggtaggag ccaaatacat gctacctatg tcaacgacta ttttaattgt tttaaattat
     1141 agtgtacagg tttatagaaa tacatccttc gtttttatag agtcatttgg tttatattgg
     1201 tctcaacgga aaaagcctat aattgaagca ggtgtaaact tgttattatc tttgcttttg
     1261 ttaatagttt ttgatatggg aatcaatgga gtacttatag ggactatcgg atcgtctcta
     1321 ggatttgtga tttggtatga agcatttatc atatataaaa cggtatttga gaaacgtttt
     1381 attcatttct ttttaacttt ctggcgaagt tttatagaat taataatttc ggcaatagtc
     1441 gtttttctat taaatgaata tttagcaaat ggaggcagta cgttccttca atttataact
     1501 aaaaccttaa taactatag
//
LOCUS       DAZKNV010000160         1459 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000160 DAZKNV010000000
VERSION     DAZKNV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.168"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..110)
                     /locus_tag="ACG8M1_002876"
     tRNA            complement(26..110)
                     /locus_tag="ACG8M1_002876"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(74..76),aa:Leu,seq:caa)
     gene            complement(128..199)
                     /locus_tag="ACG8M1_002877"
     tRNA            complement(128..199)
                     /locus_tag="ACG8M1_002877"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(165..167),aa:Gln,seq:ttg)
     gene            complement(209..281)
                     /locus_tag="ACG8M1_002878"
     tRNA            complement(209..281)
                     /locus_tag="ACG8M1_002878"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:His,seq:gtg)
     gene            complement(343..427)
                     /locus_tag="ACG8M1_002879"
     tRNA            complement(343..427)
                     /locus_tag="ACG8M1_002879"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(391..393),aa:Leu,seq:caa)
     gene            complement(448..518)
                     /locus_tag="ACG8M1_002880"
     tRNA            complement(448..518)
                     /locus_tag="ACG8M1_002880"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(484..486),aa:Cys,seq:gca)
     gene            complement(564..635)
                     /locus_tag="ACG8M1_002881"
     tRNA            complement(564..635)
                     /locus_tag="ACG8M1_002881"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(601..603),aa:Gln,seq:ttg)
     gene            complement(647..719)
                     /locus_tag="ACG8M1_002882"
     tRNA            complement(647..719)
                     /locus_tag="ACG8M1_002882"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(684..686),aa:His,seq:gtg)
     gene            complement(722..795)
                     /locus_tag="ACG8M1_002883"
     tRNA            complement(722..795)
                     /locus_tag="ACG8M1_002883"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(761..763),aa:Trp,seq:cca)
     gene            complement(802..882)
                     /locus_tag="ACG8M1_002884"
     tRNA            complement(802..882)
                     /locus_tag="ACG8M1_002884"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(846..848),aa:Tyr,seq:gta)
     gene            complement(884..959)
                     /locus_tag="ACG8M1_002885"
     tRNA            complement(884..959)
                     /locus_tag="ACG8M1_002885"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(924..926),aa:Phe,seq:gaa)
     gene            complement(995..1067)
                     /locus_tag="ACG8M1_002886"
     tRNA            complement(995..1067)
                     /locus_tag="ACG8M1_002886"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1032..1034),aa:Asp,seq:gtc)
     gene            complement(1077..1149)
                     /locus_tag="ACG8M1_002887"
     tRNA            complement(1077..1149)
                     /locus_tag="ACG8M1_002887"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1114..1116),aa:Val,seq:tac)
     gene            complement(1165..1236)
                     /locus_tag="ACG8M1_002888"
     tRNA            complement(1165..1236)
                     /locus_tag="ACG8M1_002888"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1201..1203),aa:Glu,seq:ttc)
     gene            complement(1251..1339)
                     /locus_tag="ACG8M1_002889"
     tRNA            complement(1251..1339)
                     /locus_tag="ACG8M1_002889"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1303..1305),aa:Ser,seq:gga)
     gene            complement(1379..1452)
                     /locus_tag="ACG8M1_002890"
     tRNA            complement(1379..1452)
                     /locus_tag="ACG8M1_002890"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1416..1418),aa:Asn,seq:gtt)
BASE COUNT          415 a          385 c          334 g          325 t
ORIGIN      
        1 aagaaagttg ctatattgat aattataccg gcggccgggg tcgaaccggc acgtcctcaa
       61 cggacactgg attttgagtc cagcgcgtct gccaattccg ccacgccggc aaatttaaaa
      121 ataataactg gggtagctgg attcgaacca acgcatgagg gagtcaaagt cccttgcctt
      181 accgcttggc tataccccaa gaataaaggg cgaatgatgg gaatcgaacc cacgaatgcc
      241 ggagccacaa tccggtgcgt taaccacttc gccacattcg ccatcataaa agatgttatt
      301 taatttctca ataaaaaact aagatgaaga catcttagtc aataccggcg gccggggtcg
      361 aaccggcacg ccctcaacgg gcactggatt ttgagtccag cgcgtctgcc aattccgcca
      421 cgccggcaag ttgatttatt agtactaagg cggtaaccgg atttgaaccg gtgatgaagg
      481 ttttgcagac ctctgcctta ccacttggct ataccgccat tatactatta tcaatctaca
      541 aaataaagaa taaattatag aaactggggt agctggattc gaaccaacgc atgagggagt
      601 caaagtccct tgccttaccg cttggctata ccccaagaat aaaaagggcg aatgatggga
      661 atcgaaccca cgaatgccgg agccacaatc cggtgcgtta accacttcgc cacattcgcc
      721 atggcagggg cagcaggaat tgaacccaca ctaacggttt tggagaccgc tgttctacct
      781 ttaaactatg cccctataaa atggaggaga gtggattcga accactgaac cctaaggaac
      841 ggatttacag tccgtcgcgt ttagccactt cgctactcct ccatggtggc gcgggacaga
      901 atcgaactgc cgacacacgg agcttcaatc cgttgctcta ccaactgagc taccgcgcca
      961 tattttaaaa ttattaattg aataacaaga acgacggttc cgacgggaat cgaacccgcg
     1021 atctcctgcg tgacaggcag gcatgttaac ccctacacca cggaaccagt tcattatgga
     1081 ggttaacggg atcgaaccgc tgaccctctg cttgtaaggc agatgctctc ccagctgagc
     1141 taaacctcca acattcaatt aaaatgaccc gtacgggatt cgaacccgtg ttaccgccgt
     1201 gaaagggcgg tgtcttaacc gcttgaccaa cgggccaggt aaatttgcta cggagagtaa
     1261 gggattcgaa cccttgagac agtttgcacc atctacatga tttccaatca tgctccttcg
     1321 gcctctcgga caactctcca gagtgaaaga agctcaatac tctttctcaa aatgagaact
     1381 ccggcagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
     1441 agctatgccg gaataacat
//
LOCUS       DAZKNV010000161         1459 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000161 DAZKNV010000000
VERSION     DAZKNV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.169"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(15..1154)
                     /locus_tag="ACG8M1_002891"
     CDS             complement(15..1154)
                     /locus_tag="ACG8M1_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFQ0423512.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          382 a          316 c          263 g          498 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgcccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctg
//
LOCUS       DAZKNV010000162         1440 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000162 DAZKNV010000000
VERSION     DAZKNV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.170"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            105..1406
                     /locus_tag="ACG8M1_002892"
     CDS             105..1406
                     /locus_tag="ACG8M1_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0423513.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          474 a          288 c          264 g          414 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
//
LOCUS       DAZKNV010000163         1430 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000163 DAZKNV010000000
VERSION     DAZKNV010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.171"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            45..455
                     /locus_tag="ACG8M1_002893"
     CDS             45..455
                     /locus_tag="ACG8M1_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0423514.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            469..825
                     /locus_tag="ACG8M1_002894"
     CDS             469..825
                     /locus_tag="ACG8M1_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0423515.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          527 a          210 c          267 g          426 t
ORIGIN      
        1 gaaattactg tagaattgga ttataattaa aaaggagtga gaaaatgata aaagtatata
       61 cttcgcctag ctgtacttcc tgtagaaaag caagagcatg gttgcaagcg aatcaacttg
      121 aatttgaaga gaagaatatt tttgccgaac cgttaacaga aagtgagatc aaaaagatct
      181 tggcagcgac tgaaggagga gttcaagata ttatttccac tcggtcgaaa atttacgaaa
      241 agctgggcat agattttaac gaattaactt taaagcaaat gatcgtctta ttcaaagaat
      301 atccttcatt attgagacga cctattttga ttgatgaaaa aagaatacta atcggattta
      361 atgaagatga gatccggtca tttgtccctc gtgaaattcg atgtgttgcc agaaatctga
      421 tctatttaca aaacaataac atcttaaatt catagggagg gagccttcgt ggaagtgaaa
      481 gtctatggat cagcgcactg tgtaacaagt ctgaaggcga aacaatggtt agaacaccat
      541 caattgcctt atcaatttgt tgacttagaa gaacgcgatc taagtacaga agaagcagaa
      601 gaattatgca gttttgaaga agtgcaagca gaacagctat ttgcgacttg gtctgaggct
      661 tttcacaaca ttgcgattga cctttcctgt gtaggaaaaa aacaactgat ttttttatgc
      721 acacaacata ccaatctcct cagacgtcct ttgattatta tcgatgaagt tctatttatt
      781 ggatacaatg agcagttgat ggaacagctt atcttaaata aatagacttt aactgtttta
      841 atcaagtcac tgagcatttc atacagttgt aacagtcgaa cacttagcat caagcgtgtt
      901 atgtgttctt tttttgactt tatttttcta ctatagagac atgctcaatt tatgtggtca
      961 aaattcaaat ctaggtgtgg atatagagtt aaaaatatat tgacatgtgt aaatttacat
     1021 gatatattca tttctgttgt tttaagtagc aaagcaataa aatagtattt taaaaaacat
     1081 ataaaatagt tgttgacatg ttagaaatga catgataaga taactgagtt gttaaaaaag
     1141 aaccacttgt gaagcttgat tctatcgaaa aaaacttcaa aaaagttctt gacaaataac
     1201 aaatgataag ttatgataaa tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac
     1261 ttttaaaaaa gagttgacaa ttacttgtct ctctgatatg atataaaagt tgctacggca
     1321 gccaaaaacg aatcggggaa cactcctgat gaagtagacc tttgaaaact gaacaaagta
     1381 agacaaacca aatgtgtagg gcgtcttgat tcaattcaag acaacaaaca
//
LOCUS       DAZKNV010000164         1426 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000164 DAZKNV010000000
VERSION     DAZKNV010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.172"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..1426
                     /locus_tag="ACG8M1_002895"
                     /pseudo
     CDS             6..1426
                     /locus_tag="ACG8M1_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          590 a          224 c          319 g          293 t
ORIGIN      
        1 cggtcatggc agaagaaaaa gaaccactag acaatagtcg tttgggaaaa tccaaaagaa
       61 aattagtacg attgcaaaat gaattaaacg aacaaattga aaagatgttt gaacaccaga
      121 gaaagaccaa cggtcaacca atgaacgata agagaaatgg gcattcttgg tttaggcaac
      181 aagagcgaat cgaaaataaa gtgcatagtc tgagagaaga gatcaagcaa caagaaaaac
      241 aagtagaaaa acttgaaaga caagaagaga taaaggaaat gggctataac aagtacggcg
      301 gactggatat gacgatcgag aatattccaa gaatcaaaga agaaatcgaa cgctttgaaa
      361 aaggtgaatc gactttttca gccgctacga tccgaaaata ccaacggaaa ttggaaacat
      421 tagaacagct gaaagaaaga tcggaaaaag gaaaagaaaa ccttcttcct gaagtacaag
      481 caatcattga cagcggacga gtgacgcaat ggaaaaaaat ccgaccattt attttctgaa
      541 aggctatcga aaagtcgctt tagaactgaa tgaaaacggg gaatttgagg aatctaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctgt
      661 accaactgat tttttgaagg agaaagaaaa cgatcatttt tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacgttgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaagaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccca tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcatactc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaatagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaa
//
LOCUS       DAZKNV010000165         1424 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000165 DAZKNV010000000
VERSION     DAZKNV010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.173"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(150..1337)
                     /locus_tag="ACG8M1_002896"
     CDS             complement(150..1337)
                     /locus_tag="ACG8M1_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFQ0423516.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAZKNV010000166         1388 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000166 DAZKNV010000000
VERSION     DAZKNV010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.174"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(134..433)
                     /locus_tag="ACG8M1_002897"
     CDS             complement(134..433)
                     /locus_tag="ACG8M1_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0423517.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            784..>1388
                     /locus_tag="ACG8M1_002898"
     CDS             784..>1388
                     /locus_tag="ACG8M1_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFQ0423518.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFA"
BASE COUNT          466 a          225 c          197 g          500 t
ORIGIN      
        1 aaaatacaat ataaagaaac atctgtttct ttatttagaa taaaaaaata cagactctgt
       61 tcaaataaat gaacctagcc tgcattatga gattgactat actttttaat tcattgagat
      121 gaataactcg tttttataaa tgcccaaaag taatcggtgc cgaagccatt cctcgaccta
      181 attctttttc aaattttcct attgttgata tctccatata aaacggtgat actggtttag
      241 acaattctcc cctgattgct aacggacgta aactacgttc caaattattt atgactttag
      301 gataatactg acctttttct aagcctgtct ttgcgtctat caaaagtata cgttcctttt
      361 ctttgatctc tggatttaaa acgagatcat ataattttag taccatgttt tctatttctt
      421 cacttttaga catcacgatt tcctcccaaa aatatatttc ttcccactac attctataaa
      481 caaagtatac gctacatcta gattttttta aatcattact ggattgttaa aacctttcaa
      541 tacactgtta tggcaacgat ttttatttta aaaacattct aaattaaatc agtaaaaatt
      601 tttattctaa gatttttatt agaattacgc ctaatttgtg tctctcaggg caattctaag
      661 aacgtttcaa gagatagcga cactatcgtt atcgaaaaag gcgaaaacct atctcatttt
      721 ctgctaatgt aagttggttt agcttttgtt aatatgactt tatgaaaatg gaggtaatta
      781 aatatgattt ttcctaaagt taatgaagca agcttgaata aaggatcctt ttttcatatc
      841 tatgaaaacg aagattttga actgtataat atcctttcac aaaaagaggt catcgaaaac
      901 caaataatct gccatccaat tatttacaaa tctattttca agtatgcatt ttttgcttcc
      961 aatgattttc aaagaatgga gattaccgac tgtatattcg aaaactgtga tttttcaggc
     1021 tgtatattga caaaaagcat gttgcatcgc gtgaaatttg tcaattgtaa attaacaggt
     1081 actaaattga tggaaagtta tattgggaac acgttattcg agaattgtaa aatggactat
     1141 gtaaatttat ctggttcaaa cataaaagaa agtacctttg agcactctgt cttatcaagc
     1201 gcagattttg tagactgttc cctcactaaa ataatgtttt ctactaatga tttagaaaat
     1261 gctagctttt ttgatactga tttaaaaaat atcgatttaa gtagcaactc ctttgaaatg
     1321 attgaagtac gctcggaaca tctaaaaaat tgtacgctta atcagttgca agcacttggt
     1381 tttgctag
//
LOCUS       DAZKNV010000167         1364 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000167 DAZKNV010000000
VERSION     DAZKNV010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.175"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            80..>1364
                     /locus_tag="ACG8M1_002899"
     CDS             80..>1364
                     /locus_tag="ACG8M1_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HFQ0423519.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          463 a          256 c          259 g          386 t
ORIGIN      
        1 tttaggtatt aaaaaacata tcgttctcta gtatgattaa atcacgacaa aataaacaac
       61 tgagaggacg atatgctata tgaatgattc tatcaaaaaa atgctgcgat taatagagaa
      121 agatttgatg attacagagg tctcttacga gacctttcag aagaaaaaga cgttgatcgt
      181 cgatgctgtt ttctcacctg ctccccatac ctgtagaaat tgtggttcta ctgtggtaga
      241 tggaaacggg aaagtaattg tagtgaaaaa tgggaagaag gaaacgattg tccgctttga
      301 acaatacaat cacatgcctt tggttatgcg cttaaaaaag cagcgctata cctgtaaaaa
      361 ctgtcgaacc cattggacgg ctcaaagtta ttttgttcaa cccagacatt caatcgcgaa
      421 tcatgtcaga tataaaattg cttctttact gactgaaaaa gtatctttat cttttattgc
      481 gaaaaattgt caggtatctt tgaccaccgt tattcgtacg ttgaaagagt ttaaaagcta
      541 cttaccaaag caatctaaga ggattctccc cagagtattg atggttgatg aatttcgttc
      601 gcacgcttcc atagaagata aaatgagctt tatttgcgca gatggcgaaa caggacaatt
      661 aattgatgtc ttgcctacgc gtaaattgcc tcgattaaca agctatttct taggctgcgc
      721 taatcctgaa gaagtaaaat ttttagtcac agacatgaac gccgcctact tccagcttac
      781 caaacgtatt ctgccaaatg cgaaagtagt gattgatcgg tttcatatta tcaaacacat
      841 gaatcaagcc tttaatgagt tgcgtatccg tgaaatgaat gaacttcgta aagtaggaca
      901 gaaaagtcag gcagaaaaac tgaaaaagaa ctggcgcttt ttgctaaaaa atcgtgcaaa
      961 catcaaccat tatgaataca aaacatggaa aagttttcga gcaccaaaat acccatttct
     1021 tacggaagcg atgatgattg atcgattgct tggcttttct acgtccctga aggaggcgta
     1081 tccctatttt catgaattag ttgaagcctt tcgagacaaa gaccctgact tatttttctc
     1141 cttattggca gaacttcccg aaacgttaga tgacggcttt cgggaaaagc tccaaaacct
     1201 tctgacctat gaagaaggca tcaccaacgc gatgatctat ccttacacca atggaaaaat
     1261 agaagcgaag aatacccata taaagacaat gaaacgagta tcctacggat ttaaatcatt
     1321 tgagaacatg agaattagaa tctttttgat caatcaatta atca
//
LOCUS       DAZKNV010000168         1359 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000168 DAZKNV010000000
VERSION     DAZKNV010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.176"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            383..>1359
                     /locus_tag="ACG8M1_002900"
     CDS             383..>1359
                     /locus_tag="ACG8M1_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFQ0423520.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNDSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSW"
BASE COUNT          431 a          253 c          249 g          426 t
ORIGIN      
        1 ttgtctaata gtttttattc aaaatgtttc tagattataa aatttattga ataacacatt
       61 cctaacggaa tttgtttcga tattgtgtga tttctcagag tacaatggat gtatggaaag
      121 gatccaacgg gaatttgcta tttcctcctg tagcgtttgt ctaccctgtt tagtctgtta
      181 cccgaaccac tgttatcact accaactcat tagctgtttc gataatggac tagactttca
      241 aatagtagtt tggaaggcag cttctagctc ttttatcacc gtattctatt aggcgaggtt
      301 gtggctatac agtgagtttc tgggaaatcc cacagtatcg aagcattttc caaaatttat
      361 atcgaaagga ggtccttctt ccatgaaatt atttgtcggt attgacgtta gctctgaaaa
      421 actagatgtt tgttttttaa cagacgacaa tcaattgtct atcttatctg aaatctctgt
      481 tgccaatgac atcgaaggtg cttcattcat acgagaaaca attcttgaat tcaatgacag
      541 ctaccacttt gatcaaattg tgattggcat ggagtcaacg tccatgtaca gcttccatcc
      601 ttccatgttt tttcatgaag atgagaaact aaagaagctc aacacacttg taacgattga
      661 aaatcctttt cgggtgaaac aatttagtcg catgtttgat gagaataaaa ctgatcgaaa
      721 cgatgcatta agaatcgctg atttcttgcg tattcaacga ttcacaactt cccctatcaa
      781 agaagagaaa tacatggcct tacagcgttt aacacgtact cgctatcaac ttattaagca
      841 attgattcgt acaaagcaac attttcttga aaatctaacg tacaaatgta atacgcttgc
      901 tcgagaaatg cgagacgaat cgacgagtct ttttagtgca accctcattt cactcatgac
      961 ggaagatttc acattggatg aacttgctga gcttccttta gaagctttct gtgatttact
     1021 tcaagaaaaa ggaaaaggcc gtttcaagca accagaaaaa atcgctaaag caattcaacg
     1081 tgcaattacc atgagttacc gcctaggtgc tcttgcacaa gaatcaatta atgttgtttt
     1141 aagtgttctc gtacgagaaa tacgagcact tgaaaaaaat atcaaagaat tagataaagc
     1201 catcgaacaa gtaattgttg tcattccaga atatcaatgc ttaaccagta ttccaggcgt
     1261 tggtaaagtc tatgctgccg gtttaatcgc tgaaattggt caaatcgaaa gatttgaaga
     1321 tcagacaaaa ttggcaaaat acgctggatt aagttggaa
//
LOCUS       DAZKNV010000169         1324 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000169 DAZKNV010000000
VERSION     DAZKNV010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.177"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            278..820
                     /locus_tag="ACG8M1_002901"
     CDS             278..820
                     /locus_tag="ACG8M1_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423521.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..>1324
                     /locus_tag="ACG8M1_002902"
     CDS             976..>1324
                     /locus_tag="ACG8M1_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFQ0423522.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          533 a          157 c          248 g          386 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccag
//
LOCUS       DAZKNV010000170         1284 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000170 DAZKNV010000000
VERSION     DAZKNV010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.178"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1284
                     /locus_tag="ACG8M1_002903"
     CDS             <1..>1284
                     /locus_tag="ACG8M1_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFQ0423523.1"
                     /translation="NDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRAC
                     RSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQS
                     YFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKK
                     ILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEEV
                     EFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKSQ
                     AEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYP
                     FFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNGK
                     IEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          431 a          250 c          246 g          357 t
ORIGIN      
        1 tgaatgattc tatcaaaaaa atgctgagaa taacagagaa agatttgatg attacagagg
       61 tctcttacga gacccttcag aagaaaaaga cgttggtcgt cgatgctgtt ctctcgccta
      121 ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga tggaaacggg aaagcaatta
      181 tagtgaaaaa tggaaaaaag gaaacgattg tccgttttga acaatacaat catatgcctt
      241 tggttatgcg cctaaaaaag caacgctata cctgtaaaaa ctgtcgcacc cattggacgg
      301 ctcaaagtta ttttgtccaa cccagacatt caatcgcaaa tcatgttaga tataaaattg
      361 cttctttact gactgaaaaa gtatctttat cttttattgc gaaaagctgt caggtatctt
      421 tgaccaccgt tattcgtaca ttgaaagagt ttaaaagcta tttaccaaag caatctaaga
      481 agatcctccc cagagtattg atggttgacg aatttcgttc gcatgcttcc atagaagata
      541 agatgagctt tatttgcgcg gatggcgaaa caggaaaatt aatagatgtt ttgcctacgc
      601 gtaaattacc tcgattaaca agctatttct taggttgtac caatccagaa gaagtagaat
      661 tcttggtgac agacatgaac gccgcctact tccagctcac caaacgtgtt ctgccaaatg
      721 cgaaagtcgt gattgatcgg tttcatattg tcaaacacat gaatcaagcg ttcaatgagt
      781 tgcgtatccg tgaaatgaat gaacttcgta aagccggaca gaaaagccag gcagaaaaac
      841 tgaaaaagaa ctggcgcttt ttgctaaaaa atcgtgcaaa catcaaccat tatgaataca
      901 aaacatggaa aagtttccga gcaccaaaat acccatttct tactgaagca atgatgattg
      961 atcgattgct tgagttttct ccgcccctaa aggaggcgta tccctttttt catgaattag
     1021 ttgaagcctt tcgagacaaa gaccctgact tatttttctc cttattggca gaacttcccg
     1081 aaacgttaga tgacagcttt cgggaaaagc ttcaaaacct tctgacctat gaagaaggca
     1141 tcaccaacgc aatgatctat ccttattcca atggaaaaat agaagcgaag aatacccaca
     1201 taaagacaat gaaacgagta tcctacggat ttaaatcatt tgagaacatg agaattagaa
     1261 tctttttgat caatcaatta atca
//
LOCUS       DAZKNV010000171         1277 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000171 DAZKNV010000000
VERSION     DAZKNV010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.179"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            32..1147
                     /locus_tag="ACG8M1_002904"
     CDS             32..1147
                     /locus_tag="ACG8M1_002904"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0423524.1"
                     /translation="MGGASIVASKIAKGLIDSGHEVFFVSYLESEKPQVESKYYDLYE
                     KKIFLFKNFSRFHKILEYRLFGGFVPSRYIKKEKEQLKKVLKKEKPDVIIFNTFIPSV
                     LFSEFLKYEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDSIVCLSQDTKEK
                     LSLYNNHIKVIYNPLTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPVGW
                     AIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRSEG
                     LPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGILIKNFDVQDMNNEIEKLSNNRLLM
                     EKYQKFSLERAKDFNEKKIIGEWQTLLNELGNEDVRN"
BASE COUNT          487 a          137 c          217 g          436 t
ORIGIN      
        1 gaaaatagct atactatctc cagctttctc aatgggagga gctagtatcg tggcctcaaa
       61 aattgcaaaa ggattaatag atagtggcca tgaagttttt tttgtttctt acttagaaag
      121 tgaaaaacca caagtagaat ctaagtatta tgatttatac gaaaaaaaaa tttttttatt
      181 taaaaatttt tctcgatttc ataagatatt agagtataga ttgtttggag gctttgttcc
      241 tagtagatat ataaaaaaag aaaaagaaca actaaaaaaa gttctaaaga aagaaaaacc
      301 tgatgtcatc atattcaata cttttatacc tagtgtacta ttctccgaat tcctaaagta
      361 tgaatttcca acagtgaaat taattacttg gatgcactct gatcctgatt acagcttaaa
      421 tcatattgct aaattttata aaaaagaata tagaaaaagt tttgaacgcg tggattccat
      481 tgtttgtctt tcgcaagata caaaagaaaa actttcatta tacaataacc atattaaagt
      541 tatttataac ccattgacat taagcggctc tagtttaata agtaaccttg ataaaaaaat
      601 tatttcattt actgccagat acgatataaa tattaaaggg tttgattatt tatgtgaagt
      661 agctaaaaac ttacctgttg gatgggctat aaggattgct ggagatggta cagaagaaga
      721 acgtaaagag ctgaaaagat taattgagaa aaatggtgtg ttagataaaa ttatttgcgc
      781 aggtgcatta tttggagatg aattaatcaa tcattatata gaaagttcta ttttcatatc
      841 tacttctaga agtgagggac taccattagt gttgatagaa gcaatgactt atggattacc
      901 tgtaataagt tttgatcatg gtggtgctaa ggaaatatta caagatggaa attatggaat
      961 tttaattaag aattttgacg tacaagatat gaataatgag atagaaaaat tgtctaataa
     1021 tcgtttactt atggaaaaat atcaaaaatt ctctttagaa agagctaagg attttaatga
     1081 aaaaaaaata attggtgaat ggcaaacatt gttaaatgaa ttaggaaatg aggatgttag
     1141 aaattgagga cttcgattaa aaattttaat ttatggaaag aatggtatct atatatattt
     1201 tttataggga tgattattcg tgcaataaat ttttatagtt tattaccgtc cacttttgat
     1261 agtatttttt ttaaact
//
LOCUS       DAZKNV010000172         1248 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000172 DAZKNV010000000
VERSION     DAZKNV010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.180"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..385
                     /locus_tag="ACG8M1_002905"
     CDS             <1..385
                     /locus_tag="ACG8M1_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0423525.1"
                     /translation="VVSNEEKYFYLQRNDSIMGKSFSMNNFDVIEAWQYNKEKILDAF
                     PDLHDSYYRRLCWAYFYVLDKMVLSSSYQQIPRKKTVIEFLKKNRNFILTYKGFTKSR
                     KIAIIALSFRVDWYRKLVEQKNKKN"
     gene            418..>1248
                     /locus_tag="ACG8M1_002906"
     CDS             418..>1248
                     /locus_tag="ACG8M1_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0423526.1"
                     /translation="MKTKMCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDG
                     STDNSGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDM
                     YAFLYNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANA
                     VSKLYKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKK
                     FTKKDFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLYQEKK
                     Q"
BASE COUNT          499 a          119 c          226 g          404 t
ORIGIN      
        1 tgttgtttcc aatgaagaga aatatttcta tcttcaaaga aatgatagta ttatgggaaa
       61 aagtttttct atgaataatt tcgatgttat agaagcatgg caatataaca aagagaagat
      121 tttagatgct tttccagatt tgcatgattc ctattatcgc cgactatgtt gggcatattt
      181 ttacgtgttg gataaaatgg ttttatcaag tagttatcaa caaattccac gtaaaaaaac
      241 agtaattgaa tttttaaaga agaacagaaa ttttatatta acttataagg gattcactaa
      301 atcgcgcaaa atagctatta ttgctctgag ctttagagta gattggtata ggaaattggt
      361 tgaacaaaaa aataaaaaaa attagaatgt ttaaattagt aaataaaaga aaaggaattg
      421 aaaactaaaa tgtgcagaat aagtataata gttccagttt ataatgttga aaaatattta
      481 aaaaagtgtg tcgattcaat tctaggccaa acatttaccg attttgaatt attattaatt
      541 gatgatggtt ctacagataa ttcaggaagt atatgcgatg aacttgcgaa aacagacaac
      601 cgaataaaag tgatacataa ggaaaatggg ggtctaagtg atgccagaaa tattggtatt
      661 gaggtagcaa agggagattt tattgggttt atagatagtg atgattacat tgatgaagat
      721 atgtatgcat ttttatataa caatatattg aaatatgatg cagagttatc aatgtgtggt
      781 atttatgacg tccataagaa taaagaaatt aaaaagttaa ctcctttttc tcaattggtt
      841 actaaatctg aagcaattga attagtatta gatggtaagc tagttgttgc taatgcagta
      901 agcaagctat ataaaaaaga attatttgag aatgtgagat atccaaaagg aaaaattgct
      961 gaagacgcag cagtaatact gaaaattatc aatcagtgta ataaaatcca tgttgatact
     1021 tctcaaaaat attattatta tcatcgtgga gatagtatta ctagtaaaaa atttacaaaa
     1081 aaagattttg atataattga tgtatggaat gagaatgaaa aatggattat taaaaattat
     1141 cctcaaatgt acgataaagt acatactaga gtttgttggg cttactttgt tgtgttagat
     1201 aaattagttt taactgaaga aaaaggactg tatcaagaaa aaaaacaa
//
LOCUS       DAZKNV010000173         1170 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000173 DAZKNV010000000
VERSION     DAZKNV010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.182"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..588)
                     /gene="wzy"
                     /locus_tag="ACG8M1_002907"
     CDS             complement(<1..588)
                     /gene="wzy"
                     /locus_tag="ACG8M1_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFQ0423527.1"
                     /translation="MKEKINILMFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAIC
                     TWHWRKGDSIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSES
                     DMIMVKWYSCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIV
                     VPIVFVSKLLEVRIALVHGYNALYYGDYATQSGYLQ"
     gene            complement(607..>1170)
                     /locus_tag="ACG8M1_002908"
     CDS             complement(607..>1170)
                     /locus_tag="ACG8M1_002908"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0423528.1"
                     /translation="PYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELD
                     IYGEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLE
                     ALAIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKA
                     QKGIKLRKELTSKNISNIWYEYLNQFF"
BASE COUNT          392 a          232 c          133 g          413 t
ORIGIN      
        1 ttgtaaatat ccactttgtg tagcataatc accataatat aatgcattat aaccatggac
       61 taatgctata cgtacctcta gtaatttaga aacaaaaact atcggtacta ctattataga
      121 aatgatacac cctattttaa ataaaaactt tctatcggca tcagcatctc cagattcata
      181 ccaactaact tttcttagtg tggtttttct cgtaaataag agtgctccta tgtgaaatac
      241 aaacatagaa atacaagaat accattttac cattatcata tctgattcac taggaataat
      301 ccccgtacca taagctacta ctgttgtacc gattccacga tctgttccaa taccgaatgc
      361 ccacataatg cattgcccat aactaaataa taaaaaaaga gtgaaaaaaa tcgtgtataa
      421 tgaaaatatt gaatctcctt ttctccaatg ccatgtacag attgcatata agtaaatcaa
      481 tattccaagc caatttagcc aatagttctg atttaatgaa aaagcgcaaa atattgtaaa
      541 cgcgactaac gttaacgaaa acatcaatat atttattttt tctttcacac aatatcctcc
      601 ttttggttaa aagaactggt ttaaatattc gtaccatata tttgaaatat ttttagatgt
      661 cagttctttt cttagtttaa ttcctttttg cgcttttctt accacacttt ctctatccaa
      721 aagtacccta cgcattgcat ctgttaactt atctagatta ttacattcaa caagatgacc
      781 tatttcattt ctatcaccta aatacattct tgcgccacct actggacaat ctgtagcgat
      841 aactggcact ccaatagcca gtgcttctaa catagaatta gatatacctt cataatcaga
      901 agaaattaca aatcctgccg cattttgcat cttttcatgt attttatttg taaattcttt
      961 tagatgaaca aattctgtta atccattatg gttgatataa ctttcaagct cggtttttaa
     1021 tcccccttct ccataaatat ccagttcaca ctcatatcct tcatgaataa gttttcctat
     1081 tgcatcaatc attaagggca aatttttttg tttatccaat ctacatgcag taataaattt
     1141 tttactactt gtagttttat tataataagg
//
LOCUS       DAZKNV010000174         1145 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000174 DAZKNV010000000
VERSION     DAZKNV010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.183"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            64..330
                     /locus_tag="ACG8M1_002909"
     CDS             64..330
                     /locus_tag="ACG8M1_002909"
                     /inference="COORDINATES: protein motif:HMM:NF021126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFQ0423529.1"
                     /translation="MTSTYASFDKDNLYYDFPSVSGFSSMNNKKYLLMLTRLGYSTSN
                     VRAKRNGGTVITDILLSNQYQVIPNQEIQHQATSGVKIIESEVS"
     gene            433..708
                     /locus_tag="ACG8M1_002910"
     CDS             433..708
                     /locus_tag="ACG8M1_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423530.1"
                     /translation="MTNLESRQFDPCWHQIDAQTKELLLGWEENQVVRDFSLNFIMID
                     YYNLATSMQRFPNYGMDIDSFKQKSFSGEIQNEESNNLVIPILYEPG"
     gene            718..924
                     /locus_tag="ACG8M1_002911"
     CDS             718..924
                     /locus_tag="ACG8M1_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423531.1"
                     /translation="MDGEEYPYKVAFDDLIQLSNLPKDSNMKIAGEFFAPGFLVGLVI
                     SSIATGCFLFLLFLDYIKKTEDIP"
BASE COUNT          393 a          184 c          204 g          364 t
ORIGIN      
        1 acaatcaacc aaactctaac agaatttgaa gtatatcaag aatattggga accactaaaa
       61 aaagtgactt caacttatgc atcctttgat aaagacaatc tctactatga tttcccctca
      121 gtatcaggat ttagttcaat gaacaataaa aaatatttac taatgttaac gagattaggg
      181 tactcaacaa gtaacgtccg tgctaaacgg aatggtggta cagttattac ggatattttg
      241 ctaagcaacc aataccaagt aattcctaat caagaaatcc agcatcaagc gactagcggt
      301 gtaaagatta tagaaagcga agtgagttaa acctcagata ttgcttcttt ttcatttgac
      361 gttctagaag taacaaaaga tgagttactt tatgtttatt ttcccgtcaa cttggccaat
      421 aatttgcact atgtgaccaa tttggaaagt cgacaatttg atccctgctg gcatcaaatt
      481 gatgctcaaa cgaaagaatt gttgctaggt tgggaagaaa atcaagtagt tcgtgatttc
      541 tcattaaatt ttattatgat tgattactat aatttggcga catcaatgca acggttcccg
      601 aattatggta tggacataga ttcattcaaa cagaaaagct tttctggaga aattcaaaat
      661 gaggaaagca ataatcttgt tatacctatt ctctatgaac caggttaggt ttttactgtg
      721 gacggggaag agtatcctta caaagtagct tttgacgatt tgattcaatt gtctaactta
      781 ccaaaagata gtaatatgaa aattgctgga gaatttttcg caccaggatt cttggtaggc
      841 ttggtaatct ctagtattgc aactgggtgc tttttatttt tactttttct ggattatatc
      901 aagaaaacag aggatattcc ttaggaaaat cacaatctaa atcttcccta gaaactatag
      961 aatgacaagg gggatataag caaattccta aatgattaaa tagggtgcgt tactagttag
     1021 ctccatagta agattttttc aaaattttct tgaggttgga tcaaaaaggg ctcttttcaa
     1081 ttagattaaa gacactcata caaaatagag aaacgaactt ataatcgcgt tcgtttccct
     1141 attta
//
LOCUS       DAZKNV010000175         1127 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000175 DAZKNV010000000
VERSION     DAZKNV010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.184"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            154..417
                     /locus_tag="ACG8M1_002912"
     CDS             154..417
                     /locus_tag="ACG8M1_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0423532.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="ACG8M1_002913"
     CDS             417..689
                     /locus_tag="ACG8M1_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFQ0423533.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="ACG8M1_002914"
     CDS             766..1095
                     /locus_tag="ACG8M1_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0423534.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          428 a          142 c          222 g          335 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa acatgtcatt aagtatt
//
LOCUS       DAZKNV010000176         1097 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000176 DAZKNV010000000
VERSION     DAZKNV010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.187"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1032
                     /locus_tag="ACG8M1_002915"
     CDS             <1..1032
                     /locus_tag="ACG8M1_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFQ0423535.1"
                     /translation="TRFLCHDCGRTFSAKTDLVDEHHQLTKELKQAILMELYENQSRK
                     LIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVLCMDEFKSMKSVSGSMSFICVDGT
                     THQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLVMDMNASYCQLLKTVFPNAEIVTD
                     RFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHY
                     HRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLP
                     QSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIY
                     LQQGLIFEN"
BASE COUNT          337 a          240 c          211 g          309 t
ORIGIN      
        1 acccgttttc tctgccatga ttgtggaagg accttttctg cgaaaacgga cttagttgat
       61 gaacatcatc aactaacaaa ggaactgaag caggcaattc tcatggaact gtacgaaaat
      121 caatcacgta aactaatcgc taagaagtac ttcgtctcgg atgggacggt gacacggatc
      181 ttgcgtgaag caacgaagca ttaccagtca cgtatgaact tccttccgac ggtgttgtgt
      241 atggatgagt tcaaatcaat gaagtctgtt tctggttcca tgagttttat ttgtgttgat
      301 gggacaaccc atcagctatt tacgatcctt gaagatcgca gactttacaa actaactcaa
      361 tacttcctgc actttcctag aaaagcccgt ttaaaggtca agtacctagt gatggacatg
      421 aatgccagct attgtcagtt gcttaaaaca gtctttccaa atgcggagat cgtaactgac
      481 cgctttcata ttgtccaaca catcaatcgc agcttcaatc aattacgtgt ccagatcatg
      541 aatcgttttc gaacctcaca ctctgaaaat cagaagaagt accgtcggct caagcgatat
      601 tggaaactct tactcaaaga ttccacgaca tgggagccac tcaaacggca ttatcatcga
      661 ctgtttaaac gaccaattag tcaaacagaa atcgttgatg agctgttaag ctacaacgaa
      721 gaattgcgaa ctgcgtatca tttttgtcaa ttattacgct attatttcgt taaacgaggt
      781 acggaaggct ttcaagaaac ccttaaaaca atttcatcta cgttacctca gtcgtttaaa
      841 aagaaattca cgatcttcca ttgctaccaa tcgggtattt caaatgcctt taaggtgtcc
      901 cactcaaacg gcgtcactga ggggctgaat aacaagatca agctgattaa acgaattgcg
      961 tttggttatc gcaactttta taactttcgg gcacggatct atttacaaca aggtctgatc
     1021 tttgaaaact aaaaaaatat gcggcgcaca gaacgcgccg catatcggac taagttttat
     1081 tcaaatttgt cttcacc
//
LOCUS       DAZKNV010000177         1073 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000177 DAZKNV010000000
VERSION     DAZKNV010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.188"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1073
                     /locus_tag="ACG8M1_002916"
     rRNA            <1..>1073
                     /locus_tag="ACG8M1_002916"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DAZKNV010000178         1064 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000178 DAZKNV010000000
VERSION     DAZKNV010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.189"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..>1064)
                     /locus_tag="ACG8M1_002917"
     CDS             complement(39..>1064)
                     /locus_tag="ACG8M1_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFQ0423536.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          177 c          160 g          381 t
ORIGIN      
        1 ttttagaaaa agcagtcgga ctttctaaaa gaagttcact attcgatcct gtcgatgatt
       61 tcttcaggaa aatcgtctat ttgcttgtca attttgctgt ctttgtattt ctcttcttgg
      121 atagtcaaca aaatctttgt aagattcccc cagtctactg ctcttggcgg atcgagccaa
      181 accactactt gagatgcact ttcttcatat agattattcc tattcgtgat tataacatcc
      241 gggaactcag gctttcctgc ctctatcact tccgtgttca gattaatgta caagcttaaa
      301 tttttcttga taaattgatt ataggcagca ccataagaaa aatcgatgat gatctttact
      361 ggttcagaaa tcagttgaat gggtatgtga ttgatcaata ataataaata actgaaaaaa
      421 agaaaaaatt tatcttgaag caactctttg cgttttgacg ttagatcatt tatatactct
      481 atcaaatagc aataaaatgc tggatagttt tctctaaaaa aagaaacatc aagtggaaat
      541 tcatcagctt tattaatagt gtaatgcaaa agtttaaaat gtattttggt taactctctt
      601 cggatcaatt ggctcgtctc ttctcgcaac agattaaact gattttcaaa actttcaatg
      661 aatcgttcat tcaaccattc gattgtttca tcttcatttt ttctcaagta tttttgatcc
      721 aatttatcat gaagataaag ccaagagagt gtcttattga taaaaataac ggatttttct
      781 cctaatactc cttttaagtg gtaaaatcct atatccgaaa aaaatagcga ctgattgcta
      841 gcaatatcta aagaatcagc ttgttcagcc aacaggttga ttgctaaaaa gtggaataat
      901 ttcttttttt cataagcaga cagaggataa tactgtttta aatcttttaa cattttttct
      961 gtttttataa ttataggtag cgtatacaat tccacaaaac ttatctctgt tgagttaaaa
     1021 agattatata aaaaaagccg aatgttttta ggattccctg tcaa
//
LOCUS       DAZKNV010000179         1058 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000179 DAZKNV010000000
VERSION     DAZKNV010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.190"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="ACG8M1_002918"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="ACG8M1_002918"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFQ0423537.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          377 a          134 c          182 g          365 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagtcact attactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tggactaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgacgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgt
//
LOCUS       DAZKNV010000180         1043 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000180 DAZKNV010000000
VERSION     DAZKNV010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.191"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..286)
                     /locus_tag="ACG8M1_002919"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACG8M1_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACG8M1_002920"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACG8M1_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          362 a          180 c          153 g          348 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caa
//
LOCUS       DAZKNV010000181          958 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000181 DAZKNV010000000
VERSION     DAZKNV010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.192"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>958)
                     /locus_tag="ACG8M1_002921"
     CDS             complement(<1..>958)
                     /locus_tag="ACG8M1_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423538.1"
                     /translation="YKASYNYHLIDFMYKYPRSVLKDFAKEQFTSVSTVFRYAKLLIP
                     YFRRYHITFHPFQLELNASEANIRSFFYYFYWNSTRESSDKWPFHIEQKEIEKYIVAF
                     EGIYDITLTIFQKRVFSFWLAINIERSSFRKVRVDNEYKSVISDDPHFNLLKKWSKQI
                     NLSFNSDELCFLYRIIYSFGVIDGNAIYENSHAYAHQRQNTCSYRAVENLEKVLQSMF
                     RFSLDIKDPELIFNFIAFHERSYLFYGNPDLFFNRSYIEEMKEEEPRTYHIMEKLKKE
                     LQANADLDVSKKLENWAQLFLDYYYVLDYYDLFLTNVKPIKIL"
BASE COUNT          353 a          154 c          117 g          334 t
ORIGIN      
        1 taaaatctta atcggtttaa catttgttaa aaataaatca taataatcta acacataata
       61 ataatccaaa aataattgtg cccagttttc taatttcttt gatacatcca aatccgcatt
      121 tgcttgtaat tcttttttga gtttttccat tatgtgataa gttcgaggtt cttcttcttt
      181 catttcttcg atatacgaac gattaaaaaa aagatctgga ttaccataaa atagataact
      241 tctttcatga aatgcaataa aattgaatat gagttctgga tcctttatat ctaaagaaaa
      301 acggaacatg ctttgtaaaa ctttctccaa attctcaact gctcgataag aacaagtatt
      361 ttgtcgctga tgtgcatatg catgactatt ttcatatatt gcatttccat caattactcc
      421 aaaagaataa attattcgat aaaggaaaca cagttcatcg ctgttaaaag aaagattgat
      481 ttgttttgac cacttcttca aaagattaaa atgcggatca tctgagataa ctgatttata
      541 ttcattatct actcgtactt ttctaaatga acttctttct atattaatgg ctaaccaaaa
      601 agaaaataca cgtttttgaa aaatagttaa cgtaatatca taaatcccct caaaagcaac
      661 tatatacttc tctatttcct tttgttcgat atgaaatggc cacttatcac tactttcacg
      721 tgtagaattc caatagaaat aataaaaaaa gctacgaatg tttgcctctg atgcattcaa
      781 ttctaactga aatggatgaa atgttatatg ataacgccta aaatatggaa ttaagagctt
      841 cgcatatctg aaaacagtag atacactagt aaattgctct ttagcaaaat cttttagaac
      901 acttctagga tatttataca taaaatcaat caaatgataa ttataagaag ctttataa
//
LOCUS       DAZKNV010000182          954 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000182 DAZKNV010000000
VERSION     DAZKNV010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.193"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(164..712)
                     /gene="aac(6')"
                     /locus_tag="ACG8M1_002922"
     CDS             complement(164..712)
                     /gene="aac(6')"
                     /locus_tag="ACG8M1_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFQ0423539.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          277 a          201 c          142 g          334 t
ORIGIN      
        1 tactactcga aactaagcga ctttttcaca acctctggta cacggtgttc caaaagtagc
       61 ttcttcggaa ataagttgga atttcacaaa aattcaagaa gtaattttcg taaattcctt
      121 cttatttctt gaagctgatt acttctgtca caacctcttt ttattattga gaatttggtc
      181 gaggaataat cgtttttgcc atccaaatat ccggtttgtc ccagccattt gcatttggta
      241 agacacctac gattttataa cctaattttt catagaattc atacggatgt tcacgaaggt
      301 tctggatgga agccacttta tcaaatgtat gctcatacag gtccgtttga cttaacgttg
      361 ttccatggtc taaatcatcc gtacctaaat aaatcgtgat tcctcctctg gaagctactt
      421 ctttttctaa gtaattgact aatcgagtac ctatttggtt ctttcgtcgg gagctttcta
      481 caactaatgg atgcaattcc caacctgtga taccgtattg agggattgca ccaataaatc
      541 ctactaactc atcttggtct accgctgcta ccgcgattcg ttctggattc atcatttctt
      601 ctacttcttc tgccgagctg tctccatatt cttccggcca agtcagtctc agtaaatcag
      661 aaagctgatc tttcaatact ggattattac ggtcaaattc actgattatc atacgtcttc
      721 ccccttgttc ttgcttattc taacagtcct tttgaaaaaa cgaaatgttc tcgctcaaaa
      781 atctttagct accaatcagt atctctattc tttcattatt tatcttactt ataaaataaa
      841 aaaattatac agaaacactt tattcaaaat aggaaagatc aggaaagcca tcaattggag
      901 gaaaaaactc tgtttgttca tcatgatata gattatcttt tgctttaaaa aaaa
//
LOCUS       DAZKNV010000183          929 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000183 DAZKNV010000000
VERSION     DAZKNV010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.194"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            195..896
                     /locus_tag="ACG8M1_002923"
     CDS             195..896
                     /locus_tag="ACG8M1_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0423540.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT          333 a          161 c          148 g          287 t
ORIGIN      
        1 ttattgttgt tttttataca caaatcattc gcttcaaaac aaattattca ataccattgt
       61 atatttttta cataataaca aattatattt gtaaagtatt aaaacttgtt tctaatgttg
      121 gtatgttaaa actttacaaa ttctttaaaa aaagtgacaa taaatatagt gaacaataag
      181 gagaggactt tttaatgcgt gttaataaaa tcgattttca cttttcaaaa ctcagatatc
      241 aacctgattt tgaacatttc tcggatgaag agttccaaca gatcaaggaa catactgttc
      301 ttcgttctta taaaaaagga cagatccttt tcgacgatgg tgatcccaga caacggttgt
      361 atatcttgac caaaggactc gttcgtttag aacgttatga tgaaagtgca acttattact
      421 actatgacta tgtgaataca aataaccttt ttcctatgtc aggaatgttt ggagaagaga
      481 cctacactta tacagctcaa gcgatgactg atattgaaac attctacctt cctgtttcct
      541 actatgaaaa attagcacga aaaaatcccg aacagttgat ctatatgata caaaaaattt
      601 ctaaagtagt tgaaatacat gaattgcgta tccaaatcgg attgacctct agcgcctttg
      661 accgggtaaa acaaaattta ttcattttga aagaagaatt gggcgtacca acaaaagatg
      721 gtcatatcac cattccttat ccgatcacct taaaagaatt agcagtgaat agcggcacga
      781 cacgtgaaac tgctggacaa gtaatcaaac aactacgtga ttccggactg ttagattatg
      841 acaaaaagcg ttttactttc tgtaagacag ctactactcc agctatgaga gaataacgcg
      901 aacaaaaata agcagtgacc ctgatattt
//
LOCUS       DAZKNV010000184          905 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000184 DAZKNV010000000
VERSION     DAZKNV010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.195"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..286
                     /locus_tag="ACG8M1_002924"
     CDS             <1..286
                     /locus_tag="ACG8M1_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HFQ0423541.1"
                     /translation="LFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEE
                     NLDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            279..626
                     /locus_tag="ACG8M1_002925"
     CDS             279..626
                     /locus_tag="ACG8M1_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423542.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFAELLKWSQI"
     gene            623..805
                     /locus_tag="ACG8M1_002926"
     CDS             623..805
                     /locus_tag="ACG8M1_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423543.1"
                     /translation="MNIIKKYEFGYITYEQLIEELWGYGQQLINEVGIDCFCFYIESG
                     AGYHKNRYYIFPYPPK"
BASE COUNT          342 a          106 c          176 g          281 t
ORIGIN      
        1 tcttttttta ttcaataagt tttatgaggg gcaggaagta cgacatatag gagtaactta
       61 tagcagatta gtatacacag attccctaca attagattta tttagtgatc caagaaaaaa
      121 gattgctgaa gaaaatttgg ataggattat tgataaaatt agacaaaaat atggatttac
      181 agctattata catgcttcat ctatgttaga aggtgcaaga agtattacga gaagcacttt
      241 aataggagga cacgcaggag gattaggagg tttgcataat gattgaatat aacgatagag
      301 gacgtttaaa atggtcggga ttttatttgt ctgatcatac tgaaagaatc aatgcagaca
      361 atgtacaacg tgctaatcat aatttggcaa aagaacaaat gacgactgaa gagattgcga
      421 aaatactgag aactgctgtc ataaaaaata gacccgtctg cattcaaaaa gaggaacgaa
      481 acgctgaagg ttactatcca gatgatgtag taggaaaaat tattggatat gacgagcttg
      541 gtgtatttgt ggaagaagaa aaagttcact atgatgaaat taggaatgtt tctttcgcgg
      601 aattattaaa atggagtcag atatgaacat tattaaaaaa tacgaattcg gttatattac
      661 gtatgaacag ctaatagagg aattatgggg atatggtcaa caattaatta atgaagtggg
      721 gattgattgc ttttgtttct atattgaatc cggagcagga taccataaga acagatacta
      781 tatatttcca tatccaccaa aatagtctct tagagatttt taaattttct ccaaatactt
      841 tcaattattg tgaaatattt ccttttaatt aatcaaattt tttataaaag taatatataa
      901 aataa
//
LOCUS       DAZKNV010000185          890 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000185 DAZKNV010000000
VERSION     DAZKNV010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.197"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..888
                     /locus_tag="ACG8M1_002927"
     CDS             <1..888
                     /locus_tag="ACG8M1_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFQ0423544.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DAZKNV010000186          867 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000186 DAZKNV010000000
VERSION     DAZKNV010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.198"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..823
                     /locus_tag="ACG8M1_002928"
     CDS             <1..823
                     /locus_tag="ACG8M1_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0423545.1"
                     /translation="KNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYST
                     LLRTIDDLEFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERD
                     IYINECIEIVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKI
                     TVNNYILDENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNK
                     ISNMDKIFDVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
BASE COUNT          393 a           58 c          121 g          295 t
ORIGIN      
        1 aaaaaataat atacaagaaa taaaaattgt tactgataaa atgatgaaac ttgataaaaa
       61 aatgagttta aaagttagct ctaatgatga agttggagaa ttaaaacaac aaattaatga
      121 tttgtattct actttattaa gaacaattga cgatttggaa tttaaaaata aagaaatttt
      181 aaaattagaa aagttaaaat atgacttttt taaaggtgca tcccatgaac ttaaaacccc
      241 tcttgctagt cttaaaataa tactggaaaa catgaaatac aatattggaa aatataaaga
      301 aagagatatt tatattaatg aatgtattga aatcgttgat agtttaacaa aaaatatttc
      361 tcaaatatta tcagttcatt ctatagaaaa tttgaataat gatgaagaat atttgaaaat
      421 aaatgataca ttagaagaca tattaaaaaa gtatgaaata ttagcaaatc aaaagaaaat
      481 aactgtcaat aattatatat tagacgagaa tgtttatata ggaaaaacag ctttaaagat
      541 tattctatct aatttgatta gtaatgcggt aaaatatact gatgtaaatg gggtaattaa
      601 tattgggata gttaatgatt ggttatatat agagaattca tacggtaaca ataaaatttc
      661 gaatatggat aaaatatttg atgttaaatt tgatttaaat aaggaaaata gtaatggatt
      721 aggtttatat attgtaagta atattctgaa taattacaat atagaatata aagtattgca
      781 ggatgaagaa ttttttatct ttaaaataaa aatattttct taattaagat ataattttgc
      841 aatagttatt gaaaaataga gacttat
//
LOCUS       DAZKNV010000187          816 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000187 DAZKNV010000000
VERSION     DAZKNV010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.199"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..677
                     /locus_tag="ACG8M1_002929"
     CDS             <1..677
                     /locus_tag="ACG8M1_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFQ0423546.1"
                     /translation="SSGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKID
                     NNKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRT
                     DFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGR
                     KIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRL
                     HSMGLA"
BASE COUNT          299 a          127 c          152 g          238 t
ORIGIN      
        1 attctagcgg taaatactat atttctttgt tgtgtaaaga agaaattatc gaattaccta
       61 aaactaattc cacaattggt attgacttag gtattatgga ctttgcgatt ctttctgatg
      121 gacaaaaaat tgataataat aaattcacgt ccaaaatgga aaagaaacta aagcgtgaac
      181 aacgcaaatt gtctaggcgt gctttattgg ctaaaaataa aggtaccaat ctatttgaag
      241 ctaaaaatta tcaaaaacaa aaacgcaaag tagctagatt gcatgaaaaa gtaatgaatc
      301 aacgtactga ttttctgaat aagttgagta cagaaatgat caaaaatcac gatattatct
      361 gtattgaaga cttaaacaca aaaggtatgt tgcgaaatca taaattagct aaaagtattt
      421 ctgatgtttc ttggtcaaag tttgtgacta aattacaata caaggctgac tggtatggac
      481 gaaaaatcat caaagtagat aaatggtttc cgtctagtca gatttgttca gagtgcggac
      541 ataaagatgg caagaaatct cttgaaattc gagaatggac ttgtcctgtt tgtcatactc
      601 atcatgatcg tgatatcaat gctagtatca atattctgac cgaaggtcta agactacatt
      661 ctatgggatt ggcttagatc caatcatcaa gaaccgtagg aactacgggg atagcttggt
      721 aaataagaga caccgctgtt agtaaagaaa tacgctatca agtatgctct attcccaaga
      781 agctcccact tcaagcgtta agaaccgtca ggttta
//
LOCUS       DAZKNV010000188          726 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000188 DAZKNV010000000
VERSION     DAZKNV010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.200"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            62..>726
                     /locus_tag="ACG8M1_002930"
     CDS             62..>726
                     /locus_tag="ACG8M1_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423547.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFL"
BASE COUNT          255 a          109 c          107 g          255 t
ORIGIN      
        1 ttatgaaaaa aacagtaata ttttcaagtt ttaacaattt aagtaaaaag gagcctcttt
       61 catgcaaact caagaagcga ttaaaacgtt tctcttgaag aaaaaaagca atacaaaatt
      121 agatattttt cttttcctat ctgaacatcg tttctttatt actacacaat atttagcaga
      181 tcatttccat atgtctgaat caaatttttt actatacatc aaagaattag aacaagactt
      241 tgagcgtctc aatctaacag aactgcatat tgataagcaa aaaccttttt taaagttgaa
      301 ttttgaagga attgatccgg cttactgcta ttatcgtcta tttggaagat actgcaacga
      361 atcagtcagt tatcagatct tgacttcttt gttcagctgt cagacaaatt cgattatcag
      421 tttaagtcag caaacaaact atagtgcctc ttatttgtat acgaaaatga aaaagattaa
      481 tgcattttta gcattgtacg gtttgtctat ctccttttct aataatggca gaaagtcttt
      541 ttctggaaaa gaggtacaaa ttcaatatgc agcattagat atttattgga acatcttttc
      601 aagtactgct acagaatttt atgatgaaga tccgcaagta gtggctttta tgatgaatac
      661 tttttttaaa aaagaagtac ttgaccgact aaatagcggt atgatagata aattatattt
      721 tctatt
//
LOCUS       DAZKNV010000189          725 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000189 DAZKNV010000000
VERSION     DAZKNV010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.201"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            48..725
                     /locus_tag="ACG8M1_002931"
                     /pseudo
     CDS             48..725
                     /locus_tag="ACG8M1_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612146.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          293 a          124 c          136 g          172 t
ORIGIN      
        1 aaattaaggt gtgtagacta gaagaaaaca taccaggagg aatttttatg tctaagagaa
       61 cacgaagaac tttttcacaa gaattcaagc aacaaatcgt caatctttac ttagctggaa
      121 agccacgtgt agaaatcatt cgagaatatg aactaacggc ttcagcattt gacaaatggg
      181 taaagcaatc taaaacgagt ggttcattca aagaaaaaga taatcttacg cctgaacaaa
      241 aagaattgtt agaactacgt aaaagaaacc agcaattaga aatggaaaat gatattttaa
      301 agcaagcagc gctgatattc ggacgaagag acaagtaatc gatgcgaata agcatcttta
      361 ccctatatca gcgatgtgca gaatattagg tctatcacgt cagtcctatt attatcaatc
      421 aaaaccaaag aaagacgaat cagaacttga agaagtagtc gctgaagaat ttatccgcag
      481 ccgaaaggcc tacggctcaa gaaaaataaa aaaagcctta tcaaaacgag gcattcagat
      541 cagccgacga aaaattagta gaatcatgaa aaatagagga ttaaaatcga gctatactgt
      601 tgcttatttt aaagtacatc attctacttg caatgaagcc aaaacgacaa acgtattgaa
      661 tcgtaaattc ttaagagaca acccattaga agcgatcgta acagacttga cttatgtacg
      721 agtcg
//
LOCUS       DAZKNV010000190          716 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000190 DAZKNV010000000
VERSION     DAZKNV010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.202"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(73..648)
                     /locus_tag="ACG8M1_002932"
     CDS             complement(73..648)
                     /locus_tag="ACG8M1_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFQ0423548.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          240 a          152 c          126 g          198 t
ORIGIN      
        1 ttaatttgac aaataataaa atgaaaaaac agagccagat tagcattatt ttgctaatcc
       61 agctctgttt attcagccta tttttctttt tgaatatatc aagcgttggg gcaacatagt
      121 gatgactaat gaaacaacga cgatagacaa caagcgatca aggtagtctg tacccgcctg
      181 taccaagatc acacttgttg tctgacttaa acctaaccca tgtaatagct gaacgatcat
      241 actggatcct gaggaggtga tcccgccaaa taactgaacg gtaatgatcg aagaaacgat
      301 cgttccaggt accgacaaaa tcaaagcgag taataacagt ttcaagctgt ttttatcttt
      361 gccgagatat cttggcaaaa tcaatccagc aagcaagcct gtgagaattt ggattggcga
      421 ataatacaga gaaaaaatat ctgtagtcac tccacttaaa ataccgctgg acaatcctgt
      481 cagcattcca ggtacaggcc caagcaatgc accagcaaaa atcgttccga tagaatcgag
      541 atagattggc aaacgaagcc ataaagcaat cgttcctcca atataattga tcccaataca
      601 caaagccatc actgtaagta cgcgagttgc cattttgttt ttattcattt tgttagccca
      661 tctttaacct ttccaaatct ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DAZKNV010000191          676 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000191 DAZKNV010000000
VERSION     DAZKNV010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.203"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(109..>676)
                     /locus_tag="ACG8M1_002933"
     CDS             complement(109..>676)
                     /locus_tag="ACG8M1_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HFQ0423549.1"
                     /translation="TANVLDRTFTQEQPLEAIVTDLTYVRVGKKWHYICLILDLFNRE
                     IIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDRGKEFDNQTIHEILNGFGITRSL
                     SRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYE
                     TPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          193 a          155 c          126 g          202 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgtt
//
LOCUS       DAZKNV010000192          666 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000192 DAZKNV010000000
VERSION     DAZKNV010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.204"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..655
                     /locus_tag="ACG8M1_002934"
     CDS             <1..655
                     /locus_tag="ACG8M1_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFQ0423550.1"
                     /translation="QQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQE
                     YGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQ
                     AAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQD
                     HRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          229 a          119 c          132 g          186 t
ORIGIN      
        1 tcagcaggat gtgattattg tagccgtggg ctactatctt cgttataacc ttagctatcg
       61 tgaagttcaa gaaatcttat atgatcgtgg cattaacgtt tctcatacga cgatttatcg
      121 ttgggtgcaa gaatatggca aactactcta tcaaatttgg aaaaagaaaa ataaaaaatc
      181 cttttattca tggaaaatgg atgaaacgta catcaaaatt aaaggaaaat ggcattattt
      241 gtatcgagcc atcgatgcag atggtttaac cttggatatt tggttacgta aaaaacggga
      301 cacacaagca gcctatgctt ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt
      361 tgtagtcaca gataaagccc cctctattac aagtgccttt aagaaactaa aagaatacgg
      421 cttttatcaa gggacagaac atcgtaccat taaatacctg aataatttga ttgaacaaga
      481 ccatcgtcca gtaaagagac gcaataaatt ctatcgaagt ttacgcactg cctctaccac
      541 gattaaaggc atggaagcca ttcgaggatt atataagaaa acccgaaaag aaggcactct
      601 cttcgggttt tcggtctgta ctgaaatcaa ggtattattg ggaatcccag cttaaatcat
      661 agatac
//
LOCUS       DAZKNV010000193          640 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000193 DAZKNV010000000
VERSION     DAZKNV010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.205"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..283
                     /locus_tag="ACG8M1_002935"
     CDS             <1..283
                     /locus_tag="ACG8M1_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0423551.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          214 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt
//
LOCUS       DAZKNV010000194          630 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000194 DAZKNV010000000
VERSION     DAZKNV010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.206"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>630
                     /locus_tag="ACG8M1_002936"
     rRNA            <1..>630
                     /locus_tag="ACG8M1_002936"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          156 a          144 c          196 g          134 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga gatagagctt
      421 ccccttcggg ggcaaagtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
      481 ttgggttaag tcccgcaacg agcgcaaccc ttattgttag ttgccatcat tcagttgggc
      541 actctagcaa gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat
      601 gccccttatg acctgggcta cacacgtgct
//
LOCUS       DAZKNV010000195          607 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000195 DAZKNV010000000
VERSION     DAZKNV010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.207"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            149..>607
                     /locus_tag="ACG8M1_002937"
     CDS             149..>607
                     /locus_tag="ACG8M1_002937"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0423552.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSK"
BASE COUNT          238 a           69 c          120 g          180 t
ORIGIN      
        1 atagttagaa tgaaagcata tgaacttgaa cctaatatga gaaagaagtt agcccttgtg
       61 accattagta taatgtttaa ttttaaaatg tataaaacag cgtataatat gctctggaga
      121 atatataatc gataaagagg taggaaatat gaggaaattg acctttgtga taggaattat
      181 gggaaaagga ggggcagaac gagtaattgc gaatttggca aataatttta ttcaagataa
      241 ctgggaaatt gatattataa ctatatatgg gaatcggcaa gactatgaac tgaatagaaa
      301 aatacaggta catccaataa tatgtaaaag ttcgtttcgt gcatttagac ctttggaacg
      361 ctttaaggaa cttaggaaaa aaataaggga aatacagcct gatctggtta tttcgttcct
      421 tgctgatgta aatatccatg tcattatttc attgttagga gtaaaacaaa aattaattgt
      481 ttctgaacga aatgatccac aacggaatcc agaagaacca tggattagga aaattagaga
      541 ttttctttat aaaaatgtag atggaattgt ttttcaaaca ccagacgcaa aaaaatattt
      601 tagtaag
//
LOCUS       DAZKNV010000196          604 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000196 DAZKNV010000000
VERSION     DAZKNV010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.208"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            141..539
                     /gene="spxA"
                     /locus_tag="ACG8M1_002938"
     CDS             141..539
                     /gene="spxA"
                     /locus_tag="ACG8M1_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFQ0423553.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          210 a           93 c          119 g          182 t
ORIGIN      
        1 taactttcat ttttttaaaa aaattatgaa aaaaaggtag ctatttaaaa gttgattatg
       61 tataatagaa acagatggga gattattatg atcttctgtt acaaaaaagt gattcttatc
      121 acgaaaagga gtggtgcacg ttgttaacat tatatacttc cccaagttgt acttcctgca
      181 gaaaggctcg tgcgtggttg caagaacatc agattccatt tgttgaacgt aatatttttt
      241 cagaaccatt gaacagttct gaattaaaag cgattttaca aatgacagaa gacggaacag
      301 aagaaatcat ctcgacacgt tccaaagtat tccaaaaact gaacatggat ttagatgatc
      361 tgccgttaca agaattattg gaacttgtgc aaaacaatcc tggattgctt cgccgtccaa
      421 tcatgattga tgataaacgt ctgcaagttg gttttaatga agatgaaatt cgtcggttcc
      481 taccgcgcga tgtacgacaa ttagaattac gtcaagcaca attgatggct ggattataga
      541 aggataatac gaaacttgga aaagactggc tctttgtcaa atgatgttgg taaagagaaa
      601 tctt
//
LOCUS       DAZKNV010000197          558 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000197 DAZKNV010000000
VERSION     DAZKNV010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.209"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(13..>558)
                     /locus_tag="ACG8M1_002939"
     CDS             complement(13..>558)
                     /locus_tag="ACG8M1_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0423554.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
BASE COUNT          162 a          102 c           99 g          195 t
ORIGIN      
        1 aaaatgatat ttttacacaa ctgttacggt tgttttacga aattggacgg gactttgcca
       61 gtttaatttc tgttttatcc gttcattatt gtagtaatag atatagctat cgatggctga
      121 ttttaattcc tcgaaacagt tataaacttt cccgtgaaaa atctcttgtt ttaataagcc
      181 aaaaaaattc tccataagtg aattatctaa gcagttccct ttccgagaca tgctttgaaa
      241 gattttgtac tccttcaatt tgtttctata agctttcatt tgatacgccc aaccttgatc
      301 tgagtgaaac gtacgacgat agggacaatc gttagtggtc tggatagctt cctccaaacc
      361 ttccattacc gctaatgcat tgggcttttc agagatacga taggataaaa tctcactatt
      421 gaacatatcc ataaaaggat ctagatacaa tttcttttga cggataatgc ctttggcatc
      481 cacttcatgg tatttaaatt cagttgtatc cgtcgtgatt ttctgatggc agatactggt
      541 gtagaaacga cgatggat
//
LOCUS       DAZKNV010000198          492 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000198 DAZKNV010000000
VERSION     DAZKNV010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.211"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          161 a           96 c           57 g          178 t
ORIGIN      
        1 gctaaatcac tctacaataa cggcgaaagc acaaaaaata aaaaaattat tacgttatta
       61 aaaaaacaga tgaaagatca ggttttatta gatctcattc tttcatcact tgaagggatt
      121 taatgaacta ctttttcctc tttgtcgttt ttatatattc gtattccttc aaacagtagg
      181 atagcctctt tcaatgcttg atatttgaac tgtccgttac ttaaaaattt agatgtgccg
      241 ccctcttcct agaacatatt cttttttact ttttcattaa ttgacagacc aatcgaacga
      301 aactgtaaat ttcgatagga taatgattgg tcaaactcat tcattttcaa gacatctcga
      361 ttcatattca agataggaat ctttttatca acatcacttt attcgtattt tcctctacca
      421 taaaagcttc acgctccaca aaattgtttt atacactact attcagccca ttcaacgacc
      481 aatgaatttt tt
//
LOCUS       DAZKNV010000199          477 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000199 DAZKNV010000000
VERSION     DAZKNV010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.212"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>477
                     /locus_tag="ACG8M1_002940"
     CDS             <1..>477
                     /locus_tag="ACG8M1_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFQ0423555.1"
                     /translation="FTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWP
                     EEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLP
                     KDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          192 a           71 c          112 g          102 t
ORIGIN      
        1 ctttactgca ggagaaggaa caagtattga aagtggaaca acagtctttg cagtgaaaga
       61 cggcgtaagc ttaccagaag ataaacttcc agtgttgaaa gcaaaagatg gttatacaga
      121 tgcgaaatgg ccagaggaag caactcaacc aattacagca gatgatacag aatttgtatc
      181 aagtgcaaca aaactggatg ataaatctga cgctgacaaa tataatcctg aaggtcaaaa
      241 agtgactaca gaattgaata aggaaccaga cgcatttgag ggaattaaga acaaagaaga
      301 tttaccaaaa gatactaagt atacttggaa agaaaaagta gatgttagcg cagctggaaa
      361 taaaaaaggg actgttgtag tgacatatcc agatggatca tctgatgaag ttgaagtaga
      421 tgttacagtg acagacaatc gttctgacgc cgataaatat gagccaacag tagaagg
//
LOCUS       DAZKNV010000200          424 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000200 DAZKNV010000000
VERSION     DAZKNV010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.216"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..193)
                     /locus_tag="ACG8M1_002941"
     CDS             complement(<1..193)
                     /locus_tag="ACG8M1_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFQ0423556.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTG"
BASE COUNT          155 a           71 c           39 g          159 t
ORIGIN      
        1 caccagtaaa gaaatggaaa tctttagttt ttttaatatt atcagttagt aactttttat
       61 aatcataaaa aaaataagta gttctatctg agcgatactc ttttataata ctgaattcgg
      121 aattaaaaac cacgataggt aactttaaac aaacatgaag agactttaat aagacttctt
      181 tatctgaaaa cacttttgtt tctctctttc ctttctacat cattaaatag tattttatac
      241 gttatctaaa atactattcc tctgtcaaaa taagctaact tacttcatta taaaatatcc
      301 acttatcgct ttcatgtata ttccaccgta aaaagtacat tttatcaccg agaactcatc
      361 atttttcatc atgatgaata ctatttacat atatctagtt caaagacaat aattattatg
      421 atcc
//
LOCUS       DAZKNV010000201          421 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000201 DAZKNV010000000
VERSION     DAZKNV010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.218"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>421
                     /locus_tag="ACG8M1_002942"
     CDS             <1..>421
                     /locus_tag="ACG8M1_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFQ0423557.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGEREKQFAYSAHTSCDDNGFI"
BASE COUNT          154 a           73 c           87 g          107 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgagaaa aacaatttgc ttattctgcc catacttcat gcgacgacaa tggatttatt
      421 c
//
LOCUS       DAZKNV010000202          415 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000202 DAZKNV010000000
VERSION     DAZKNV010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.219"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..339)
                     /locus_tag="ACG8M1_002943"
     CDS             complement(<1..339)
                     /locus_tag="ACG8M1_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423558.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAZKNV010000203          382 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000203 DAZKNV010000000
VERSION     DAZKNV010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.220"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>382
                     /locus_tag="ACG8M1_002944"
     CDS             <1..>382
                     /locus_tag="ACG8M1_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFQ0423559.1"
                     /translation="FDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAGIQAVANN
                     IGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATSIHELAHA
                     RMHKFSELDTATKELQAEMTSYIV"
BASE COUNT          140 a           68 c           76 g           98 t
ORIGIN      
        1 tgtttgatat cacacaaaca cagttaaaac ctgaagacta tccgaaaatc tttccgaacc
       61 gtgtctttga ttttcaattg gataaaaaag gacagtcaga acttcaagct gggattcaag
      121 cggtagccaa caatattgga atacaaattc gagatatgac agaaagtgaa gtctatcaaa
      181 gagaattagg acaagcacgt ggggcgtatg ttcgtaacga atttactggc gaagaagaaa
      241 tcgtcatgaa tactcgaaat actcctacgc agcatttagc tacaagtatt catgaattag
      301 cccatgcaag aatgcacaaa ttttcagaat tagataccgc aactaaagaa ttgcaggcag
      361 aaatgacttc ttatattgtg tg
//
LOCUS       DAZKNV010000204          380 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000204 DAZKNV010000000
VERSION     DAZKNV010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.221"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>380
                     /locus_tag="ACG8M1_002945"
     CDS             <1..>380
                     /locus_tag="ACG8M1_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFQ0423560.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHK"
BASE COUNT          133 a           71 c           62 g          114 t
ORIGIN      
        1 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
       61 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      121 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      181 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      241 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      301 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      361 aggatatatt agccataaaa
//
LOCUS       DAZKNV010000205          368 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000205 DAZKNV010000000
VERSION     DAZKNV010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.denovo.223"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          147 a           46 c           54 g          121 t
ORIGIN      
        1 ttaatatcat ataaaacgat gaaagcgcat acttttaaga ggggttgtat gtaattttaa
       61 tacctatacc aatttaaaga ggatttttca gattttcact tacaaattta taaaaaaaca
      121 atataattga tactttgatt ttgcgaacat tttgcctttc cgcctaattc agctttaata
      181 ccttgattat atcagtaact aatcgccttt ttagctaatt taagcatcaa ataattatcc
      241 ttaatcaggg taaaaaataa cgaataaatg gatttttgga ataggtaaaa actagatcgg
      301 tttctgacga aaaataacat taaaaaggaa atataaaata acatggagcg tgggaggaat
      361 aaagaaat
//
LOCUS       DAZKNV010000206        13915 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.063, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000206 DAZKNV010000000
VERSION     DAZKNV010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.063"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..445
                     /locus_tag="ACG8M1_002946"
     CDS             <1..445
                     /locus_tag="ACG8M1_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423561.1"
                     /translation="SWQLPNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRV
                     ANRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGE
                     KPSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            446..1390
                     /locus_tag="ACG8M1_002947"
     CDS             446..1390
                     /locus_tag="ACG8M1_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423562.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            1394..1597
                     /locus_tag="ACG8M1_002948"
     CDS             1394..1597
                     /locus_tag="ACG8M1_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HFQ0423563.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(1897..2133)
                     /locus_tag="ACG8M1_002949"
     CDS             complement(1897..2133)
                     /locus_tag="ACG8M1_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0423564.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(2316..2687)
                     /locus_tag="ACG8M1_002950"
     CDS             complement(2316..2687)
                     /locus_tag="ACG8M1_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HFQ0423565.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(2684..4012)
                     /locus_tag="ACG8M1_002951"
     CDS             complement(2684..4012)
                     /locus_tag="ACG8M1_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFQ0423566.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(3973..4302)
                     /gene="mobC"
                     /locus_tag="ACG8M1_002952"
     CDS             complement(3973..4302)
                     /gene="mobC"
                     /locus_tag="ACG8M1_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFQ0423567.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(4560..4931)
                     /locus_tag="ACG8M1_002953"
     CDS             complement(4560..4931)
                     /locus_tag="ACG8M1_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0423568.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            5076..5261
                     /locus_tag="ACG8M1_002954"
     CDS             5076..5261
                     /locus_tag="ACG8M1_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFQ0423569.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            5419..5586
                     /locus_tag="ACG8M1_002955"
     CDS             5419..5586
                     /locus_tag="ACG8M1_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423570.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            6204..6871
                     /gene="vanR-B"
                     /locus_tag="ACG8M1_002956"
                     /pseudo
     CDS             6204..6871
                     /gene="vanR-B"
                     /locus_tag="ACG8M1_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
     gene            6874..8217
                     /gene="vanS-B"
                     /locus_tag="ACG8M1_002957"
     CDS             6874..8217
                     /gene="vanS-B"
                     /locus_tag="ACG8M1_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFQ0423571.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            8388..9194
                     /locus_tag="ACG8M1_002958"
     CDS             8388..9194
                     /locus_tag="ACG8M1_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HFQ0423572.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            9212..10039
                     /gene="vanW-B"
                     /locus_tag="ACG8M1_002959"
     CDS             9212..10039
                     /gene="vanW-B"
                     /locus_tag="ACG8M1_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HFQ0423573.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            10036..11007
                     /locus_tag="ACG8M1_002960"
     CDS             10036..11007
                     /locus_tag="ACG8M1_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFQ0423574.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            11000..12028
                     /gene="vanB"
                     /locus_tag="ACG8M1_002961"
     CDS             11000..12028
                     /gene="vanB"
                     /locus_tag="ACG8M1_002961"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFQ0423575.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            12034..12642
                     /locus_tag="ACG8M1_002962"
     CDS             12034..12642
                     /locus_tag="ACG8M1_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFQ0423576.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(12894..>13915)
                     /locus_tag="ACG8M1_002963"
     CDS             complement(12894..>13915)
                     /locus_tag="ACG8M1_002963"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0423577.1"
                     /translation="PPSFRIQRGGKSRGKAAAAGSGKQKASNGERFLKKIERTGGEAV
                     NRLTRRRKVYEAIHTLRQEKGYEIASLCALSGIPRCSYYKWLHREESASEKENTLLLE
                     EIIRLYSEVKGIYGYRRMTLNVNSRLKRNYNHKRIYRLMKSVHMQAVIRRKKKHYVIL
                     EPRVTAENVLNREFTANGPNEKWLTDVTEFKLINGKKAYLSAILDLHDKSIVAYALGQ
                     SNNNQLVFDTFDRAVRANPGAHPLFHSDRGYQYTNRQFKAKLDGIHATQSMSRPGRCI
                     DNGPMEGFWGILKSEMYYLRQFHTFEELKKAIDEYIDFYNTRRLQAKLKGLAPLAYRN
                     QTLVA"
BASE COUNT         3563 a         3255 c         3621 g         3476 t
ORIGIN      
        1 gtcctggcag ctccccaaca ataacgccga gatacgccgg ttaaagggcc gcattgagga
       61 attgacccgc caaaaggagg cggcctatgt gggatgggag tttgacggcg gcactgtgga
      121 gatcaaccgg gtggccaacc gcctgcaaat cttctttgag gggaagccgg atgctgctgt
      181 acgcgacgag ctgaaaagca acggtttccg ctggtcgccc aaggccgggg catggcagcg
      241 gcagttaaac gacaccacaa tccgcgtcgc tgaccgtatc aagtgcatcc agcccctttc
      301 cggcgaaaag cccagcgcct tacagcttgc ggcccgcagg gagaaagaaa agccctctat
      361 ccgggcgcag ctcaacgcgg ccaagaccga acaggccaag cagccaccgg cgcgggaaaa
      421 atcaaaggga ttggaggtag agtaaatgca gaagtttgaa aatgtggacg ttctggccgc
      481 gctggaacag atcatgcggc agaacaccgc gttttatcaa agtgactttg gcattgacaa
      541 agacattatc aggcgggatg ccgccagcga tcaggccgca gacaagaccc tgctctggat
      601 gtcccggccc tccgggacgt actgtttccg ggaacgtgat gttttcctga aagacacccg
      661 acagtacaac acatggaaat tttacgggga gcagacccgt gacaagatac tggcctacgc
      721 ggtggagctg accggcacac agggcggcac tatccggggc aatctctatg agctggacta
      781 tccgcagcat ttccggcacg tcattgaaac cgcccagccg gtgagtgtga accggctctt
      841 ttatgagcat ggcacccgtg acatcccgga gagccagcgt tttgacggaa gccctgaccg
      901 ggtattggga aactttttgt actatgaggc ccagccccat gacccggctg tgctgcagga
      961 ggcgctacgg acggagcagc acagccgggg gcgggccgtc cccggcgatt tcaaagtcca
     1021 cgtcaccgct ttgcatgaca gccggattga aaccgaggcc cggcgtattg tggacagcct
     1081 gaaagatctg tccgcgccta acagccccaa taaaacgcat ttcatggtgg agatctcccc
     1141 gcactttgcg gcgattgctt ccaccaagga taatgaccgg ctctttgcca tgctgcccta
     1201 taaatccctg tgttttaccg ggatgaaagg caggcatggc gtgtatgccg tgattaaccg
     1261 ggacgagcgc cgggatgtga gtattcgcag gccccggccc tctatccgca agcagctatc
     1321 cgacagcaaa caggccgcca gcccaaaaaa ggcggcggcc agaaccaaaa agaatgaatt
     1381 ggaggtataa ggaatgatgc actttaccgt ggaggaagaa aacctgatct gtatgtacca
     1441 caatgcagac cggcgcagaa cgataaacag gctcaccgcc gtcatgccgg ttatggatgg
     1501 ggatatgcgg gcgcaggccc agcagaccct ttccaagctg gaacgcatga cggatgccga
     1561 ctatgacggc cagaagttcc acttcacaga cgaataacga acagcagacg ccgggcgcgg
     1621 cggccatgtg gtcgcttgcg tccggcgtct tttctttttg cctattccta cgcatttaga
     1681 acccggtatt gtcggggata ggatgaagta ttcgcttgcc cctgcaaaca tgcgggagaa
     1741 gccttgcagc gggcggtttt caatccctta aatgcgtagg ttgcagctat aattagaccc
     1801 ctgaaacaga tatagccgcg cagcgggtgt atctgtttca ggggtgtgca ggtgatagcc
     1861 gcaaagcggc gtaagagggt gcagccctct tgccgtctat ctctgttcca gcgggaagct
     1921 cggcaatgct tccagcagtt tcagggaaat gcgctgccgt atatcttcgt caatgacttt
     1981 cttctttttg ccgtttgcct gtctgatctc caccgtggaa agctcgttga tgtagtcagc
     2041 ataatgggcc aacacttttt ccgtggccca cctctcaccg gcaacggcgg ctttgatcgt
     2101 ttcatagtcc agcagctttt cttgtccgtc catcctgata cccccgtcag actgattttt
     2161 tctatgatac catattcgga agcatggaac cagagaaaac ggcgcttttc tgctggtaaa
     2221 ttctacgcat ttagaacagc acttcggcgg ggataggata aaacacccac ataccccgct
     2281 gaccatgccg gaaaagcctt gaaatataag ggcttttaca gctctaagtg cgtaggtttc
     2341 cagtatcttt tccgctggcg ctcggcctct ttgcggcggc gcatccgttt ggagcaggcc
     2401 gcgcagtatt tggcccggtt agacttcggc gtgaacgtgg ccccgcactc acagcagcgt
     2461 ttcacttcgt cccggtcttt ggtgatctcg gcatacaggg ccgcatccag cgggaggaca
     2521 gcggccttaa accagcggca cagaagcgaa taggaaatgc tctgtacgca aatacattct
     2581 tcgccgtcgt ccagcaacag gcagttgccg tcacaatagt tgcagcactc atgcgtcagc
     2641 ttccgggcct tgcgatattg agggtaattc attcgtggaa tactcatagc tcttgcgtcc
     2701 attcctttcc cggcgtcata cgcaaaatgc cgtccacatt ctgcttgatg atgccgtatt
     2761 cctgcatctg ctttttcgct tcgccgtact tctcatacag ccgttccttt tcctcggcca
     2821 atcgcttgta ctcggctttc agggcgtaca gatcggggag ctttttcaca ccctgtccct
     2881 ttagggcctt tgccgcagct tcatacaaaa tcaacgtgct ttcatgctca cgccggaatt
     2941 ttgccttatc cgctgcattg cggtattcca tagccacggg ccagagctgc ttgtaggtag
     3001 aaatattctt tatcagcacc gccatatccg caagccggtg ttccatagct ttgagggtag
     3061 cggcggcctc gtcgctggcg gcggtgatct cggccacttt gctttccaaa tccgggtagg
     3121 tgtctatccc atgttcagtc aggaaattca aagtctttgc ggcctgcttc aaattgtgga
     3181 gcttcgccca cctctcatag cctgccgact gctgggcctt aatgttgttt tccagatcaa
     3241 tccgcaaaga aatccccttg cgctctttgg gcgctctggt gataacgcgg cctttgatac
     3301 gctctttgat ggcttcctcg gtgtaggctt cccccaatgt cttgcagcgg gtaaagcgtt
     3361 cctgtccggg agcgcggaaa gaaataaact ttcccggctt gatctcatag ccctgcgcct
     3421 gcatgagccg caggaaatca tcaaaatctt ttgcctgcgg gatagcggcg tcaatggctg
     3481 ctttgagctt cgctttccag ctcgtccctt tccgctgggc gtcccactcg gcatagctct
     3541 tgcccttact ctggccgggc ttcaccacgg acaatccgtt ttccttgcac agcctgtcgc
     3601 tggtgcgccg gatataggca tagctctgtt tgttggaaat gtacttgcgc tgatttacca
     3661 tatccacggc acagaaaata atgtgattgt ggacgtggcc cttatcaata tgggtagtca
     3721 gcacataggg atatttccct tgcagcactt cctcggcaag ctgcttcccg atctcatggg
     3781 cctgttccgg cgtggcttcg ccgggggcaa aggattgtat caggtggtgg cccagattat
     3841 tgcccttttg gtatgcctgc gccagcagca tttcaaattc aatgtccgct gtttcataag
     3901 agcaggcaaa ggaggccacc agcagcttgc cgtcagtttt gtccgggttc tcgatgtagt
     3961 caagggcttt tttcagcgtt gacttgatag gatgtatctt tgtaactgcc atatctgcgc
     4021 cagcgccccc tttatatcct cgatgtcctg tgcgtacacc ggccccatac cgttcagcct
     4081 ctttgcaatc tgattgacgt tgacgccgat cttctgtatc tcggcggtct gcgcccggat
     4141 gtcgctggtg tccatgttga cgatatagcc gtcaatgagc atcttccggg cgtaggctga
     4201 aaagttcttc gtatgcagca gcgccatttt ctgttcaatc atagcccgtt cctccggcgt
     4261 cacagggacg cgcagcacga tttttcgctt tctgtttgcc atgcttcacc gtcctttcca
     4321 ttcaggggtt tggggatttc cccaacaagc aaaacggacg cggcccggca gggacggggc
     4381 aggccgtttt tccgggagtg gctacactcc ctatgcttgc tacgttactg tttctccact
     4441 aacaagacgt ttccaaagcc ccaaactacc cgcaaaatag ccctctggaa agaaaaaagt
     4501 gcaaaaaaat agaagctacg ctgtgcagct cccgctaaaa gtaaaacaga ggatgccagt
     4561 tacacatcct ccgtttcatt cttcttcggc ttttcaatta gtatggcgct gtcaatcgcg
     4621 ccctcgatga tcggcaggta ttcttcgggg cagagtttca gcttgtggct gaccctttgc
     4681 cgcagttcgc tttcctcccg catgatctcc gggttaaagt agcgttccac aggaagcccg
     4741 caggctttaa taagctgtat gacaaccggc agactgggaa tggccccgtc gttttcgatg
     4801 ttggcaagat agcgccagtc aatatttatt ttctctgcca ttgctttgcg cgaaacgcgc
     4861 tttgcttgcc gggccgcttt cacatccgcg ccgaaagttt caaagccggg acaatcttca
     4921 atattcgcca tatcgcacct cccacttaca ttgtatattt catactctgc ccgtggaatg
     4981 ttggtatatg cacctttctt aaagtttata tttcacattt tgtttctttt attcttcgag
     5041 caaaagaatt ataatgtacc ctgtggaggt gtactatgga ctacatgacg ttgaaagagg
     5101 caggcgagaa atggggtgtg cccccacgat ggataaacta ctattgtgct gcgggacgca
     5161 tccccggcgc tgtaaagatg gcgacgatct ggctcattcc caaaactgcg gaaaagccga
     5221 ttgacaggcg tacaaagaaa ggaaaggcgg ttactgaata gtataatgaa accggcgcat
     5281 tttggatatg gttttgaaga gagagaaagc atggtatttt gtcacggaaa aactataaga
     5341 tgatagatgg caggctgctc cagaccgata aaaagtattc tcatctgaaa cagaaagaaa
     5401 agatttacac atggatgtat gaagaagcga aactttatca tgacagaaat ggaaaatgcc
     5461 cgaaacaaag acgaggaagc tgctgctgta tcagccgtat atggtagaat tgaaaaggcc
     5521 ggcatctgga ttctttatgg tgaagtctcc agacattgga taactgctgg tctaatgcgc
     5581 ctttgagtat ggggtgattg attttaatac cggggaggta cggctttttg aggaaaatat
     5641 tctgggattt acatttggcg attattacat ttcctgtaac tgcaaggaca cggatgatga
     5701 agatatgagg aatatagact tgctgatttt ctactgtctt gaacggtatt aggactgaat
     5761 ctgctgcgcg gagtgcggca agagcgaccg gagggagtac acacaggccc tgcctgtgtg
     5821 aaaagccata ccgcaaggtg cattcgcaaa aaagaggccg cgcattttgc tgaggcttgg
     5881 ggtgtcccca acaagcaaaa cgagaacgcc gcaggcgggc aagtggtgga tcagaatatc
     5941 cgtaaaggat attctgatcc attgcttgcc agtattatcg ggatgttttg acaaccgctg
     6001 taatcgaaac atcccaaaca ttaagaaggt gttaattatt attatcttga tttaattcgt
     6061 ttaaaccaat aatatagata catacaccat gaaaagaagc gagtatccca atgacggatg
     6121 attaaaatcc gaaaagaaat cgctttgaaa ctacagggaa actacagact gttatgttat
     6181 cttcttaaaa tggagggatt tttatgtcga tacgaattct acttgtcgag gatgatgatc
     6241 atatctgtaa tacagtaagg gcgtttctgg ctgaggcagg atatcaggtg gatgcctgca
     6301 cagatggaaa tgaggcatac accaagtttt acgaaaacac ttatcaactg gttattcttg
     6361 atattatgct gcccggtatg aacgggcatg aacttttgcg tgaatttcgt gcgaaaaatg
     6421 atactcccat tctgatgatg acagccctgt cggatgacga aaaccaaatc cgggcgtttg
     6481 atgcagaggc agacgactat gtaacaaagc cattcaagat gcagatttta ctaaagcggg
     6541 tggaagccct gctgcggcgc agcggtgcgc tggcaaagga aatccgtgtc ggcaggctga
     6601 cacttctgcc ggaggatttc acggtacttt gtgacggtac agagctgccc ctgacacgaa
     6661 aagaatttga aatccttttg ctgctggtgc agaacaaagg cagaacctta acgcatgaaa
     6721 tcattttgtc acgtatatgg ggatatgact ttgagggtga tggcagcaca gtccacactc
     6781 ccacactcat atcaaaaatt tgcgggccaa gctgccggaa aatatcatca aaaccattcg
     6841 cggtgtagga taccgattgg aggaatcata ataatggaaa gaaaagggat tttcattaag
     6901 gttttttcct atacgatcat tgtcctgcta ctgcttgtcg gtgtaacagc aacactgttt
     6961 gcacagcaat ttgtgtctta tttcagagtg atggaattac agcaaacagt aaaatcctat
     7021 cagccattgg tggaactgat tcagaatagc gataggcttg atattcaaga ggtggcaggg
     7081 ctgtttcact acaataacca atcctttgag ttttatattg aagataaaga gggaagcgta
     7141 ctctatgcca caccaaatgc caatacatca aatagtttta gacccgactt tctttatgtg
     7201 gtacatagag atgataatat ttcgattgtt gctcaaagca aggcaggtgt gggattgctt
     7261 tatcaagggc tgacaattcg gggaattgtt atgattgcga taatggttgt attcagcctt
     7321 ttatgcgcgt atatctttgc gcggcaaatg acaacgccga tcaaagcctt agcggacagt
     7381 gcgaataaaa tggcaaacct gaaagatgta ccgccgccgc tggagcgaaa ggatgagctt
     7441 ggcgcactgg ctcatgatat gcattccatg tatgtcaggc tgaaagaaac catcgcaagg
     7501 ctggaggatg aaatcgcaag ggaacatgag ttggaggaaa cacagcgata tttctttgcg
     7561 gcagcttctc atgagctaaa aacgcccatc gcggctacaa gcgttctgtt ggagggaatg
     7621 cttgaaaata tcggtgacta caaagatcat tctaagtatc tgcgcgaatg catcaaaatg
     7681 atggataggc agggcaaaat catttccgaa atactggagc ttgtcagcct gaatgatggg
     7741 agaatcgtac ccatagctga accgttggac atagggcgca cggttgccga gttgctgccc
     7801 gattttcaaa ccttggcaga ggcaaacaac cagcggttcg tcacagatat tccagccggg
     7861 caaattgtcc tgtccgatcc gaggctgctc caaaaggcac tatccaatgt catattgaat
     7921 gcagttcaga acacgccgca gggaggcgag gtacggatat ggagtgagcc tggtgctgaa
     7981 aaatgccgcc tttttgtttt gaacatgggc gttcacattg atgatactgc gcttccaagg
     8041 ctgttcaccc cattctatcg cattgatcag gcgcgaagca gaaaaagtgg gcgaagcggt
     8101 ttaggacttg ccatcgtaca aaaaacgctg gatgccatga gcctccagta tgcgctggaa
     8161 aacacctcgg atggcgtttt gttctggctg gatttaccgc tcacatcaac attgtaaata
     8221 tttaaaactt aaatgatttt gaccgacagg tataaccctg ccggtctttt tttgctgcta
     8281 caggaaaact acagactggc tacagggaaa gtacagatgc gcttgccata ataacaatcg
     8341 taccagccac aaatcgtagt tttattgcaa aggaggcatt cgatcaaatg gaaaaaagca
     8401 actatcattc caatgcggat catcacaaac ggcatatgaa acaatccgtg gaaaagcggg
     8461 cttttctatg tgcgttcatt atttcgttca cagtctgcac gctgtttttg gggtggagac
     8521 tggcttccgt attggaggca acacagatac cgcccatccc tgcaactcat acaggcagca
     8581 gcactgacgt agtggagaat ttggaggaaa acgctcttgc caccgccaaa gaacagggag
     8641 atgaacagga atggagcctg attttagtga acaggcagaa ccccatcccc gcacagtacg
     8701 atgtggagct tgagcaacta tcaaatggtg agcggataga tattcggatt tctccctatc
     8761 ttcaagattt gtttgatgcc gcaagaactg atggagttta cccgattgtc gcatccggat
     8821 accgaacaac agaaaaacag caagaaatta tggatgaaaa aattgccgaa tataaggcga
     8881 aaggctacac ctctgcacag gctaaagcgg aagcagaaac ttgggtggcc gtgccgggaa
     8941 cgagcgagca tcagcttggt cttgctgtgg atatcaatgc ggacggaatt cattcaacag
     9001 gcaacgaggt ttatagatgg ctggatgaaa acagctatcg ttttggtttt attcgtcgct
     9061 acccaccaga caagacagag ataaccggtg tgagcaacga gccgtggcat taccgatatg
     9121 ttggcatcga agctgccaca gagatgtaca accaaggggt ttgccttgag gaatatttaa
     9181 aaccagaaaa atgagaaaag gatgttatgt tatggacaga aaaagattga cacagcgttt
     9241 cccgttcctg cttccaatga gacgggcgca gagaaaaatg tgcttttatg cgggaatgag
     9301 atttgacggc tgtcgctatg cgcagacgat aggggaaaaa tcgctttccc atttgctctt
     9361 tgaaacggat tgcgcattat acaaccacaa taccggattt gacatgatat accaggaaaa
     9421 caaggtgttc aacttaaagc tggcagcaaa gaccttaaac ggcttattga taagaccggg
     9481 ggaaaccttt tctttctggt ggctggtacg ccatgcggac aaagataccc cctataaaga
     9541 cggccttacg gtgaccaatg gtaaactcac caccatgtcg ggcggcggta tgtgccagat
     9601 gagcaattta ctattttgga tgttcctgca tacgccattg acaattatcc agcgcagagg
     9661 tcacgaagta aaggagtttc cagagccaaa cagtgacgag attaaagggg tggatgcaac
     9721 catttcagag ggctggattg atttaaaagt gcgaaacgat accgactgca cctaccaaat
     9781 atgggtgacc ttagatgatg agaaaatcat cggtcaggtg tccgccgaca aagagcccca
     9841 agcattatac aaaattacaa atggcagtat ccagtatgtc cgtgaaagtg gcgggattta
     9901 tgaatatgcc caggttaaac ggatgcaagt tgccttaggt accggggaaa taatagattg
     9961 caagctgctt tatacaaaca aatgcaaaat ctgttatccc ctcccggaaa gtgtggatat
    10021 tcaggaggag aaccaatgag aaaaagtgtg ggcattactg tttttggatg cgaacaggat
    10081 gaggcaaatg ctttccgcgc tttatcgccg gattttcata ttatccctac gctgattagc
    10141 gatgcgatat cggcagacaa cgcaaaattg gccgctggca atcaatgcgt tagcgtaggc
    10201 cataagtccg aggtttccga ggcgacaatt cttgcgctga gaaaggtcgg ggtaaaatac
    10261 atttctaccc gcagcatcgg ctgcgatcac attgatacga ctgccgccga gagaatggga
    10321 atctcggttg gcacggttgc gtattcgccg gacagcgttg cggattatgc tttgatgctg
    10381 atgctgatgg ccatacgggg tgcaaaaccc accatgcacg ccgtggcgca acaagatttc
    10441 agattggatc gtatccgggg gaaagaactg ggggatatga ctgtgggagt tattggaacc
    10501 ggccatatcg ggcaagcggt cgtcaaaagg ctgcggggat ttggatgcca tgtgctggcc
    10561 tatgataaca gccgaaaaat ggatgcagat tatgtccagc ttgatgagct tctaaaaaac
    10621 agcgatattg ttacgctcca tgtgccgctt tgtgcggata cccgccatct gatcggtcag
    10681 aagcaaattg gagagatgaa gcaaggcgca tttttaatca acaccgggcg cggagcgctt
    10741 gtcgataccg gggcgctggt ggaggcgttg gaaagcggaa agctgggtgg tgcggcactg
    10801 gatgtgttgg agggcgagga tcagtttgtt tataccgatt gctcgcagaa agtgcttgac
    10861 catccctttt tgtcgcagct tttaaggatg ccgaatgtga tcatcacacc ccatacggcg
    10921 tactacactg agcgtgtgct gcaggatact acagaaaaaa caatcaggaa ttgtctcaat
    10981 tttgaaagga gtttacagca tgaatagaat aaaagtcgca atcatcttcg gcggttgctc
    11041 ggaggaacat gatgtgtcgg taaaatccgc aatagaaatt gctgcgaaca ttgatacgga
    11101 aaaattcgat ccgcactaca tcggaattac aaaaaacggt gtatggaagc tatgcaagaa
    11161 gccatgtacg gaatgggaag ccgacagtct ccccgccata ctctccccgg ataggaaaac
    11221 gcatgggctg cttgtcatga aagaaagcga atacgaaaca cggcgtattg atgtggcttt
    11281 cccggttttg catggcaaat gcggggagga tggtgcgata caggggctgt ttgtattgtc
    11341 tggtatcccc tatgtgggct gtgatattca aagctccgca gcttgcatgg acaaatcact
    11401 ggcctacatt cttacaaaaa atgcgggcat cgccgttccc gaatttcaaa tgattgataa
    11461 aggtgacaag ccggaggcgg gtgcgcttac ctaccctgtc tttgtgaagc cggcacggtc
    11521 aggttcgtcc tttggcgtaa ccaaagtaaa cggtacggaa gaacttaacg ctgcgataga
    11581 agcggcagga caatatgatg gaaaaatctt aattgagcaa gcgatttcgg gctgtgaggt
    11641 cgggtgtgcg gtcatgggga acgaggatga tttgattgtc ggcgaagtgg atcaaatccg
    11701 gctgagccac ggtatcttcc gcatccatca ggaaaacgag ccggaaaaag gctcagaaaa
    11761 tgcgatgatt acagttcccg cagacattcc ggtcgaggaa cgaaatcggg tgcaggaaac
    11821 ggcaaagaaa gtatatcggg tgcttggatg cagagggctt gcccgtgttg atcttttttt
    11881 gcaggaggat ggcggcatcg ttctaaatga ggtcaatacc ctgcccggtt ttacatcgta
    11941 cagccgctac ccacgtatga tggccgccgc aggaatcacg cttcctgcac tgattgacag
    12001 cctgattaca ttggcgttaa agaggtgata agtatggaaa atggtttttt gtttttagat
    12061 gaaatgttgc atggcgtccg ttgggatgcc aagtacgcca catgggataa cttcacagga
    12121 aaaccggtgg atgggtatga ggtgaatcgc atcatcggca caaaggccgt ggcgtttgct
    12181 ctgcgcgagg cacaaatcca tgcggctgcg cttggctatg gcttgctttt atgggatgga
    12241 tatcggccaa gaactgcggt ggactgcttc ctgcgttggg cagcgcaacc ggaggacaat
    12301 ctcacaaaag aaaaatttta ccccaatata gagcgagccg agttgattac aaagggttat
    12361 gtggcctcac aatccagcca tagccgtgga agcgcaattg atcttacgct ctaccacctg
    12421 gatacagggg aacttgtttc aatgggaagt aacttcgatt ttatggacga acggtcgcat
    12481 catacagcaa aagggatagg ggatgcagag gcacaaaatc gaagatgctt gcgtaaaatc
    12541 atggaaagca gcggatttca gtcttatcgc tttgaatggt ggcactataa gttgattgat
    12601 gagccatacc ccgataccta ttttaatttt gccgtttcat aatgaaagta ttggttttgt
    12661 atcagatttt ggatttgata aaatctatgc tggtcatgga caatctttta ctggaaagtg
    12721 gttaaagcat cttttgtaat acattgcaaa ttatagtatt caatctgccc agcggcagaa
    12781 aagaaaaaaa ccgctgttgg gcagaccttt cccacgccca ttttgtattt tgctggcggc
    12841 ggttttgaga aatgaaccgc cccctgtcaa gtagacagat gaaaaaagaa aaattacgcc
    12901 acgagggtct ggttcctgta agcaagggga gccaggccct ttaacttagc ttgaagccgc
    12961 cttgtattgt aaaagtctat gtattcgtcg atggctttct tcaattcctc gaaggtatga
    13021 aattgccgga ggtagtacat ttcagatttg agaatccccc agaagccctc catagggccg
    13081 ttgtcgatgc agcggccggg ccgggacata ctctgcgttg catggatacc gtccagcttt
    13141 gctttgaact gccggttggt gtactgatag cccctgtcgc tgtgaaacag aggatgggcg
    13201 ccggggttgg ctctcaccgc tctgtcaaag gtgtcaaaaa caagctgatt gttgttggat
    13261 tggcccagtg catacgcaac gatgcttttg tcatggagat caaggatcgc actcaggtat
    13321 gctttcttcc cattgataag tttgaattct gtgacatctg tcagccattt ctcattggga
    13381 ccatttgccg taaattctct gttcaatacg ttttccgcgg taacacgcgg ttctaatatg
    13441 acatagtgct ttttctttcg gcgtatcacg gcctgcatat gtacactttt catcaggcgg
    13501 taaatccgct tgtggttgta gtttcttttg agccggctgt tcacattcag cgtcatacgg
    13561 cgataaccgt agatgccttt tacttcgctg tacaaacgga tgatttcttc cagcaagagg
    13621 gtattttctt tttctgaggc actttcttcc cggtgaagcc atttgtagta agaacagcgg
    13681 ggaatcccgg ataacgcgca taacgatgcg atttcatatc ctttttcctg acgaagcgta
    13741 tggatcgcct catagacctt cctgcggcgt gtgagcctgt ttaccgcctc ccctccagtt
    13801 cgttcaattt ttttaagaaa tcgttctcca tttgaagcct tctgttttcc gcttccagct
    13861 gccgcagctt tgccgcggct ttttcctcct cgctgtattc ggaaggaggg cggcg
//
LOCUS       DAZKNV010000207         8100 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.091, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000207 DAZKNV010000000
VERSION     DAZKNV010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.091"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(134..577)
                     /locus_tag="ACG8M1_002964"
     CDS             complement(134..577)
                     /locus_tag="ACG8M1_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFQ0423578.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="ACG8M1_002965"
     CDS             complement(795..2135)
                     /locus_tag="ACG8M1_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0423579.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="ACG8M1_002966"
     CDS             2404..3300
                     /locus_tag="ACG8M1_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFQ0423580.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="ACG8M1_002967"
     CDS             complement(3450..4391)
                     /locus_tag="ACG8M1_002967"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFQ0423581.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5637
                     /locus_tag="ACG8M1_002968"
                     /pseudo
     CDS             4517..5637
                     /locus_tag="ACG8M1_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            5895..7397
                     /gene="eat(A)"
                     /locus_tag="ACG8M1_002969"
     CDS             5895..7397
                     /gene="eat(A)"
                     /locus_tag="ACG8M1_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFQ0423582.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7464..7991
                     /locus_tag="ACG8M1_002970"
     CDS             7464..7991
                     /locus_tag="ACG8M1_002970"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0423583.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         2686 a         1511 c         1600 g         2303 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc ttttttgttg
     5281 ggagcgaaga tggtttctgg tttcgattta gtcagccaaa tcactggatt ggaaaaaaag
     5341 atcgaacaag cagatgtcat cattacagga gaagggcgga tcgatcagca aacgatccac
     5401 ggaaaagttc catacggtgt agcagtgctt gcaaaaaaat atcgaaaacc aataatcgct
     5461 atttgcggaa gtagagacca agagctagaa ggactttctg attttctccc aattgtctta
     5521 agtattcatt tgggtccaat aggtttagaa gaagcaatgg aacacaggca aacattagaa
     5581 aaaacaaaaa tcttaggaca gacacttagc agatttttca ccatcctccc gaagtagttg
     5641 acaaaatcat tttctttatg ctatcgtaat ttcaaatata ggacaaagtg agggatccgt
     5701 gcattgaaaa attaagtcga ttgatgaaag ctgcattcag actgtacctt gtggagacaa
     5761 ggaagcagtg tgcagatttt cgggattggc ttggtttttt cgatgtatgg gtctttttgt
     5821 gtgtatccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg tcttttttta
     5881 cgaggtgatg gaaaatgtct aaaatcgaaa taaaaaatct gacattcggc tacgacagcc
     5941 aaggcacatt attatttgaa caagcaaatc taaattttga cacacaatgg aaactaggac
     6001 ttatcggacg aaacggtcga ggaaagacaa ctttactgaa tattctacaa aacaaactac
     6061 cttatcaagg gcaagtaatc catcagcaag aatttgccta tttcccgcaa cagacaaaag
     6121 ataaagaacg tttaacctat tacgtgttaa atgatattac ggattttgag atatgggaaa
     6181 tcgaaagaga gctccaattg atgcaaacag atcctgaaat cttatggaga gaattcagca
     6241 cactatcggg gggagagaag acaaaagtcc tactggcact tttatttgtg gatgacactc
     6301 atttcccgtt aatcgatgaa ccaacgaatc atttggatat ctctggtaga aaacaagtag
     6361 cggcttattt gaaaaagaaa aaacaaggct tcatcgtggt cagccatgac cggggattta
     6421 tcgatgaagt agtggaccat gttttagcaa tcgaaaaaag tcaactggaa ctttatcaag
     6481 ggaatttctc tatctatgaa gaacagaaaa aacttcgtga tgaatttgaa atggctcaaa
     6541 atgaaaaatt gaaaaaagaa gtcagtaggc taaagaaaac agcagctgaa aaagccgaat
     6601 ggtctcgttc ccgagaagga gataaaacaa agaaacaagt cggattcatc gatactgaat
     6661 ctagacgagt gaataaagga gcagtgggtg ctgatgctgc acggacgatg aaacgatcca
     6721 aagcaatcgt gaatcggatg gagacccaga tcagcgagaa agaaaaacta ttaaaagata
     6781 tcgaatatat cgattctttg acgatgaata gccaagcgtc tcaccataag cgacttttaa
     6841 gcgtagaaga tcttcaatta gggtatgaaa atctgttatt cgagccaatt cattttacaa
     6901 tcgagcctca tcagcgggtg gcgatttcag gtcctaacgg tgcaggaaag tcatccatta
     6961 tccattatct tctgggggca ttcaacggca aggttatagg agaaaaatac cagccaaaac
     7021 atctgagcat tagttatgca agccaaaatt atgaagacaa tcgaggaacg ttggcggaat
     7081 ttgcagagaa aaaccaagta gactaccaag catttttgaa caacctccga aagcttggga
     7141 tggaaagaga tgtttttcat aacaagatcg agcagatgag tatgggccaa cggaaaaaag
     7201 tggaattggc taaatcttta tcacagccag ctgaactata tacatgggat gaaccattga
     7261 attatttgga tgtcttcaat caagaacaat tagaacaact gatcttgaac gtgaaacctg
     7321 ccatgttact agtggaacat gatcaaacct tcctggataa agtatctact gagattattt
     7381 ctcttgagag aatctaaccc ttgtaatctc aagaacaaca aggtatggtt aaggggaact
     7441 ttgccaacga aggagagaat cacatgcttt atgtaacgag acacggagaa acaacttgga
     7501 acgcacaagg attagtttgc ggacgggcag atgtgccgct gactgaaaaa ggacagatgc
     7561 aggcacagaa actagcagaa aaggtagtag atttgcctgt tccaatcacg aaaatcatcc
     7621 attcccctct tcaacgagca agagatacag cacaagcagt tgctgatcgt ctcagcttgc
     7681 cgctgaccgt tgatgaacga ttggtagaaa tggattttgg ggattatgat ggactgccaa
     7741 gcaaagatga gaactttcaa aaagcacgtt tagcgttcgc tgtacgattc ccaaatgggg
     7801 agtcagtctt agatgtgtat gcacggatcg ttcctttatt gaaagaatgc atcgaagacg
     7861 aagaaaatgt ctatctgtta gtttgccata atgccttgat aagagtgatc aatgcttatt
     7921 ttcatccgat gcctaatgag gggttcttta cattcatggt agataataca gaattggttt
     7981 cttatgagta attatgtttt tgtgttattt aaataaaata tttcaaggca ctgcttttgc
     8041 ttagcagtgc cttttttagg ttatgacaat tcttttgata atataaactc aacctttaga
//
LOCUS       DAZKNV010000208         6676 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.100, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000208 DAZKNV010000000
VERSION     DAZKNV010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.100"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            117..782
                     /locus_tag="ACG8M1_002971"
                     /pseudo
     CDS             117..782
                     /locus_tag="ACG8M1_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            818..1063
                     /locus_tag="ACG8M1_002972"
     CDS             818..1063
                     /locus_tag="ACG8M1_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0423584.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1166..2035
                     /locus_tag="ACG8M1_002973"
     CDS             1166..2035
                     /locus_tag="ACG8M1_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0423585.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLLECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2016..2750
                     /locus_tag="ACG8M1_002974"
     CDS             2016..2750
                     /locus_tag="ACG8M1_002974"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0423586.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2783..3691
                     /locus_tag="ACG8M1_002975"
     CDS             2783..3691
                     /locus_tag="ACG8M1_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFQ0423587.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3688..4230
                     /gene="sat4"
                     /locus_tag="ACG8M1_002976"
     CDS             3688..4230
                     /gene="sat4"
                     /locus_tag="ACG8M1_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFQ0423588.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4323..5117
                     /locus_tag="ACG8M1_002977"
                     /note="aph(3')-IIIa"
     CDS             4323..5117
                     /locus_tag="ACG8M1_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFQ0423589.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            5393..5524
                     /locus_tag="ACG8M1_002978"
                     /pseudo
     CDS             5393..5524
                     /locus_tag="ACG8M1_002978"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            5600..6345
                     /locus_tag="ACG8M1_002979"
                     /pseudo
     CDS             5600..6345
                     /locus_tag="ACG8M1_002979"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6456..6635
                     /locus_tag="ACG8M1_002980"
                     /pseudo
     CDS             6456..6635
                     /locus_tag="ACG8M1_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibD"
BASE COUNT         2287 a         1005 c         1461 g         1923 t
ORIGIN      
        1 tttccattta gatagtagtg gaaagacctc tatttatctt ttgaaagtga atacaaaaat
       61 aaagcacact ctgctataat ataggtgatt aatccatttg agagaggtgc tttatcatgt
      121 atcaaaatta taccataaac caactttgtt tgcctataga tcttgaaatt aaattagaag
      181 aaaatgattt tgctcatgcc attgtgcagt ttgttgactc tattcccgat gaagtctttc
      241 ttccttatta tcaatctatg ggtagacccc aatatcatcc tcgtatgcta ctttccatta
      301 ttctttgtgc ctatattcaa ggggtttatt cgggccgcca aatacaaaat atgctgatag
      361 atagtattcg gatgcgctac ttatctcaag agcaattccc taactttcgt actattaatc
      421 gttttcgcgt tcatccgatt atgaacgata ttctagatca ttcatttgtt caatttcgtg
      481 agctactggt tcaaagtggc ttaatcagtg gcagtgctct atacattgat ggtacaaaaa
      541 ttgaagcgga tgcgaataaa tactctttcg tttggaaaaa aagtatttta aagtataagg
      601 atagccttga tcaaaaagcc cttgaaaact accaacaaat ggtggaaaca aaaatcttac
      661 ctgagttaat agatgattta aaggatgaac tttctataga agagattgaa aggattcgtc
      721 aatctttgga agaaaaggaa aatcaattaa ttgaagcgat tgaccaaacc gaaacagtag
      781 aagggggctg acccattatt aataaggagt ggacaacatg attgatgtaa atgagctatt
      841 ggaagaagct attagagaaa ctgaaaatct aaatgatggc gaagtttttc ttgttaaaga
      901 tttattcaag ggatatgtgg ggaataggat acccagaaag gatcgacttc tgcttggaac
      961 gttattttta aaccatgtta gcaaaatgaa tggtaattta aaggctattg aaaagacttc
     1021 atctaatcag cagaggtata aaaagacaat tgataagttt taactatctt ttgtgaaatt
     1081 aaaaaaatta taaatatgtt gagtagaagc aaaagatttg gcttggaatt tttacagcag
     1141 tgaatcgata aaaggagcat gcttgatggt agataatatt attaaatcag tagcagagaa
     1201 attatcctct ctgtcttata tagaaggtat tgttttaggt ggttcacgtg caaggggcac
     1261 ccatacagag gattcggata tagatatcgg catctattac aattcagaat catttgacat
     1321 aaatactatt aatcaattcg ctacaaagct ggatgatgag catagaaata accttgttgt
     1381 acctcccgga gcatggggtg attggattaa tggcggcgga tggttagtca taaacgggta
     1441 tcatgtggat ttaattttac gtgatattaa acgtgtggaa caaataatga aagatacaga
     1501 gcacggaatt gttactgcca attatcagac tgggcatccc catggttata ttagtgcaat
     1561 gtatcgagga gaattagcga ttagcaaaat actatatgct aagaatgaaa gcttatgcga
     1621 attaaaaaaa caggcagaaa cttatcccaa tgctttgcag aaaagtttag ttaacttttt
     1681 tatgtttgaa gcagggttct ctttaatgtt tgtaaaagca aattcgggaa cagacgataa
     1741 atattatatt gcgggtcatg tttttcgtat agtttcatgt ttaaatcaag tgttatttgc
     1801 atgtaataat gcttattgta tcaacgaaaa gaaagctata aaactgcttg aaacttttga
     1861 acataaacct gaaaaatata ccgagaaggt aaatcatatt tttgaagtac tcggtatctc
     1921 acttttggaa tgctacgaca tgaccgagaa gctttataat gaagtgaatg aaattgtatc
     1981 ggagataaat aactttttaa acgaggagag ttcagatgaa agaaaacaaa tatgatgata
     2041 atatattttt tcaaaaatac agtcaaatga gtcgctcgca gaaaggactg gctggtgcgg
     2101 gagaatggga gactttgaaa aagatgctac ctgattttaa gggtaagcgt gtgcttgatt
     2161 taggatgcgg ctatggatgg cactgtatat atgcgatgga aaacggtgct tcctctgtag
     2221 taggtgttga tatttctcat aaaatgctcg aagtagcaaa aggaaaaacc cattttccac
     2281 agattgaata tgaatgctgt gccatagaag atgtggattt cccagaggag agctttgatg
     2341 taatactaag ttcgcttgcg tttcattatg tagcagacta tgagaattta ataaaaaaga
     2401 tatataggat gctgaaggct ggtggcaatt tagtttttac agttgaacat cctgttttta
     2461 ctgctcatgg aacacaagac tggtattata acgaaaaagg agaaatactg catttcccgg
     2521 tggacaatta ttattatgag ggcaaacgga cagctatgtt tttggaagaa aaggttacaa
     2581 aatatcatag aacactgacc acatatctaa atacactgct ttcaaatagt tttataataa
     2641 atcagattgt ggagccacag ccgccagaga acatgatgga tattccgggg atggcggatg
     2701 aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa gaagatgtaa taatatagaa
     2761 aaaataaacg aggagtatgt aaatgagatc agaaaaagaa atgatggatt tagtactttc
     2821 tttagcagaa caggatgaac gtattcgaat tgtgaccctt gaggggtcac gcgcaaatat
     2881 taatatacct aaagatgaat ttcaggatta tgatattaca tattttgtaa gtgatataga
     2941 accgtttata tctaatgatg actggcttaa tcaatttggg aatataataa tgatgcaaaa
     3001 gccggaggat atggaattat tcccacctga agaaaaggga ttttcctatc ttatgctatt
     3061 tgatgattac aataaaattg atcttacctt attgcccttg gaagagttag ataattacct
     3121 aaagggcgat aaattaataa aggttctaat tgataaagat tgtagaatta aaagggacat
     3181 agttccgact gatatagatt atcatgtaag aaagccaagc gcaagggagt atgatgattg
     3241 ctgcaatgaa ttttggaatg taacacctta tgttattaaa ggattgtgcc gtaaggaaat
     3301 tttatttgct attgatcatt ttaatcagat tgttcgccat gagctgctga gaatgatatc
     3361 atggaaggtc ggcatcgaaa caggctttaa attaagtgta ggcaagaact ataagtttat
     3421 tgaaaggtat atatccgagg atttgtggga gaaacttttg tccacctacc ggatggattc
     3481 ctatgaaaac atatgggaag cattatttct atgccatcaa ttgttcaggg cggtatccgg
     3541 tgaggtggcg gaaaggcttc attatgccta tccggagtat gataggaata taacaaaata
     3601 taccagggac atgtataaaa aatacactgg taaaaccggc tgcctggata gcacatatgc
     3661 cgctgatata gaagagaggc gggaacagtg attacagaaa tgaaagcagg gcacctgaaa
     3721 gatatcgata aacccagcga accatttgag gtgataggta agattatacc gaggtatgaa
     3781 aacgagaatt ggacctttac agaattactc tatgaagcgc catatttaaa aagctaccaa
     3841 gacgaagagg atgaagagga tgaggaggca gattgccttg aatatattga caatactgat
     3901 aagataatat atctttacta ccaagacgat aaatgcgtcg gaaaagttaa actgcgaaaa
     3961 aattggaacc ggtacgctta tatagaagat atcgccgtat gtaaggattt cagggggcaa
     4021 ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa aaacttgcat
     4081 ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta tcataattgt
     4141 ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa caactttgaa
     4201 aaagctgttt tctggtattt aaggttttag aatgcaagga acagtgaatt ggagttcgtc
     4261 ttgttataat tagcttcttg gggtatcttt aaatactgta gaaaagagga aggaaataat
     4321 aaatggctaa aatgagaata tcaccggaat tgaaaaaact gatcgaaaaa taccgctgcg
     4381 taaaagatac ggaaggaatg tctcctgcta aggtatataa gctggtggga gaaaatgaaa
     4441 acctatattt aaaaatgacg gacagccggt ataaagggac cacctatgat gtggaacggg
     4501 aaaaggacat gatgctatgg ctggaaggaa agctgcctgt tccaaaggtc ctgcactttg
     4561 aacggcatga tggctggagc aatctgctca tgagtgaggc cgatggcgtc ctttgctcgg
     4621 aagagtatga agatgaacaa agccctgaaa agattatcga gctgtatgcg gagtgcatca
     4681 ggctctttca ctccatcgac atatcggatt gtccctatac gaatagctta gacagccgct
     4741 tagccgaatt ggattactta ctgaataacg atctggccga tgtggattgc gaaaactggg
     4801 aagaagacac tccatttaaa gatccgcgcg agctgtatga ttttttaaag acggaaaagc
     4861 ccgaagagga acttgtcttt tcccacggcg acctgggaga cagcaacatc tttgtgaaag
     4921 atggcaaagt aagtggcttt attgatcttg ggagaagcgg cagggcggac aagtggtatg
     4981 acattgcctt ctgcgtccgg tcgatcaggg aggatatcgg ggaagaacag tatgtcgagc
     5041 tattttttga cttactgggg atcaagcctg attgggagaa aataaaatat tatattttac
     5101 tggatgaatt gttttagtac ctagatttag atgtctaaaa agctttaact acaagctttt
     5161 tagacatcta atcttttctg aagtacatcc gcaactgtcc atactctgat gttttatatc
     5221 ttttctaaaa gttcgctaga tagagttcta tattagagat gtaaagagtt ttggtgaaga
     5281 ggtttgtgag tatggctttt ataaccaggg tgcaatgaga agcactaaca gcagctagct
     5341 taagaacgca taggatatac tttttatgga agtcacagag gaggaataaa atttgaacag
     5401 gattaacaga gtaacctcta ttcttattca gctgcaatca aaaaaaataa ttcctgccaa
     5461 agaaattgca cagcgattta atataagctt aaggacagtt tacagagata tccggacact
     5521 tgaagaagcc ggaataccaa ttggatctga ggccggaaaa ggatattttc ttgtagaggg
     5581 cttcctactt ccgccggtaa tgtttacagc ggcggaagtg ggtgcattga ttacagcagg
     5641 gaaattttta aattgccatg gagatgaatc atttataaag gattttgatt cagctatgta
     5701 taaaatcaaa tctattttga agcatggtga aaaaaactat gcacaggagt tggagaacag
     5761 tattaacgtg tacagcacat ctggacagaa aaatacattg gcggataacg ttattgcagc
     5821 aattcagact gcaatctgca ataaaagggt aatatcaatt caatatcctg catcaggagg
     5881 gcaagaaccg gaaagcagaa tgatagagcc tatatcactg gggttttatg aacagaactg
     5941 gtacttaatc ggttttgcag gctaagaaat gaatatagga attttcgtgt ggatcggatt
     6001 aaaagcattt gcatagaaga agagctctgt caaagccatg atggctcttt ggaacaaata
     6061 ttaaaacaaa tgctttcata taaaaaacta tataatgtaa ttcttagagc tgaaaaaggg
     6121 gagacataca attctatcaa gaacaggtat tctctcggct tccttgaaga aaccgatttg
     6181 ggaagtaaaa tggaaatcga attccagaca gattcctttg agatattgag caagcagctg
     6241 attgaatatg gatcaggcat tgaaatagtc caacctgatg aattaaaatg cataacccgt
     6301 aaacacctgg cacaaattac gaatcactgc ctaaacttga tttagagaaa gcgattggtc
     6361 tgttatgtat tttttgtaag gtttcatatc ccctgctgac atacagctgt cagtgtatta
     6421 tgatattcta ctatcaaaaa ggaggattga aaaatatgaa accaaagata attatgcaca
     6481 cacaaattag ccttgatggc cgcattaaag gctttgataa tccggaagtt tactaccagg
     6541 ttgccggggg aattcattcg gatgcggtgc tgtttgggtc caatactgtt tttactgcat
     6601 ttgaaaaata tcctgctgaa acagaggctg attttggata aagtccgtat aattgtgtaa
     6661 aagtaaaaag gccata
//
LOCUS       DAZKNV010000209         4393 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.124, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000209 DAZKNV010000000
VERSION     DAZKNV010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.124"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            193..1104
                     /locus_tag="ACG8M1_002981"
     CDS             193..1104
                     /locus_tag="ACG8M1_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFQ0423590.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1257..1742
                     /gene="vanZ-A"
                     /locus_tag="ACG8M1_002982"
     CDS             1257..1742
                     /gene="vanZ-A"
                     /locus_tag="ACG8M1_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFQ0423591.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2267..3907)
                     /gene="merA"
                     /locus_tag="ACG8M1_002983"
     CDS             complement(2267..3907)
                     /gene="merA"
                     /locus_tag="ACG8M1_002983"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFQ0423592.1"
                     /translation="MNQFRMRIQGMTCTGCEKHIEKALESMGALNAKADFSQSEAVFQ
                     LPDDYAIENAIEAVKKINYQPEEVEKLPVQKRVMTNNKEDYDLLIIGSGGAAFSAAIK
                     AVEYGSKVGMIERGTVGGTCVNIGCIPSKTLLRAGEINQSAHVNIFEGLHTSTGEVEL
                     DRLVDQKNELVDDLRKQKYTNLIDDYGFDLIKGEAKFIDENTVTVSGQTYSAQRFLIA
                     TGASPLLPRITGLKEVDYLTSTTLLELRKVPKRLTIIGSGYIGRELGQLFHNLGSEVT
                     LIQRSKRLLKEYDPEISEAMEKALIEQGIKLISGATYERVEQDGNIKKVHIIVNGKNK
                     VIESDELLVGTGRKPNTEVLNLSAAGVQVGPNNEIKINAFAQTSNRKIYAAGDVTLGP
                     QFVYVAAYEGGIAAGNAIGGLNKAIDLSVVPGVSFTSPQFATVGLTQQQAKEKGYEVK
                     KAVLSLENVPRAIVNHNTTGVFKLVVDRKTQKILGVHIVSENAGEVIYGASLAVKFGL
                     TVADLKDTLAPYLTMSEGLKLAALAFDKDISKLSCCAG"
     gene            complement(3921..4319)
                     /gene="merR"
                     /locus_tag="ACG8M1_002984"
     CDS             complement(3921..4319)
                     /gene="merR"
                     /locus_tag="ACG8M1_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFQ0423593.1"
                     /translation="MAYFISSFSEKCGVNKESIRYYERKNLLPEPDRTNSGYRVYSEE
                     DVKRVKFIKHLQEIGFSLNEIYKLLGVVDKDNIRCEGMFEFVSKKEREIQKKIENLNR
                     IEYMLKDLRARCPDEKELYACPIIEVLIEN"
BASE COUNT         1370 a          778 c          757 g         1488 t
ORIGIN      
        1 acgtgagttg aaattttgac aacctaattt ttctaaggaa attggtgata atagtaaatc
       61 cagtagggcg aaataattga ctgtaattta cggggcaaaa cggcacaatc tcaaacgaga
      121 ttgtgccgtt taaggggaag attctagaaa tatttcatac ttccaactat atagttaagg
      181 aggagactga aaatgaagaa gttgtttttt ttattgttat tgttattctt aatatactta
      241 ggttatgact acgttaatga agcactgttt tctcaggaaa aagtcgaatt tcaaaattat
      301 gatcaaaatc ccaaagaaca tttagaaaat agtgggactt ctgaaaatac ccaagagaaa
      361 acaattacag aagaacaggt ttatcaagga aatctgctat taatcaatag taaatatcct
      421 gttcgccaag aaagtgtgaa gtcagatatc gtgaatttat ctaaacatga cgaattaata
      481 aatggatacg ggttgcttga tagtaatatt tatatgtcaa aagaaatagc acaaaaattt
      541 tcagagatgg tcaatgatgc tgtaaagggt ggcgttagtc attttattat taatagtggc
      601 tatcgagact ttgatgagca aagtgtgctt taccaagaaa tgggggctga gtatgcctta
      661 ccagcaggtt atagtgagca taattcaggt ttatcactag atgtaggatc aagcttgacg
      721 aaaatggaac gagcccctga aggaaagtgg atagaagaaa atgcttggaa atacgggttc
      781 attttacgtt atccagagga caaaacagag ttaacaggaa ttcaatatga accatggcat
      841 attcgctatg ttggtttacc acatagtgcg attatgaaag aaaagaattt cgttctcgag
      901 gaatatatgg attacctaaa agaagaaaaa accatttctg ttagtgtaaa tggggaaaaa
      961 tatgagatct tttattatcc tgttactaaa aataccacca ttcatgtgcc gactaatctt
     1021 cgttatgaga tatcaggaaa caatatagac ggtgtaattg tgacagtgtt tcccggatca
     1081 acacatacta attcaaggag gtaaggatgg cggaatgaaa ccaacgaaat taatgaacag
     1141 cattattgta ctagcacttt tggggtaacg ttagcttttt aatttaaaac ccacgttaac
     1201 taggacattg ctatactaat gatacaactt aaacaaaaga attagaggaa attatattgg
     1261 gaaaaatatt atctagagga ttgctagctt tatatttagt gacactaatc tggttagtgt
     1321 tattcaaatt acaatacaat attttatcag tatttaatta tcatcaaaga agtcttaact
     1381 tgactccatt tactgctact gggaatttca gagagatgat agataatgtt ataatcttta
     1441 ttccatttgg cttgcttttg aatgtcaatt ttaaagaaat cggattttta cctaagtttg
     1501 cttttgtact ggttttaagt cttacttttg aaataattca atttatcttc gctattggag
     1561 cgacagacat aacagatgta attacaaata ctgttggagg ctttcttgga ctgaaattat
     1621 atggtttaag caataagcat atgaatcaaa aaaaattaga cagagttatt atttttgtag
     1681 gtatactttt gctcgtatta ttgctcgttt accgtaccca tttaagaata aattacgtgt
     1741 aagatgtcta aatcaagcaa tctgatcttt catacacata aagatattga atgaattgga
     1801 ttagatggaa aacgggatgt ggggaaactc gcccgtaggt gtgaagtgag gggaaaaccg
     1861 gtgataaagt aaaaagctta cctaacacta tagtaacaaa gaaagcccaa ttatcaattt
     1921 tagtgctgag gaattggtct ctttaataaa tttccttaac gttgtaaatc cgcattttcc
     1981 tgacggtacc cctttaagcg gtagaatcct tttttgatac gatttaatta tctatattaa
     2041 gcacgtaagg caacaatcgc atcttcaata atatcttgct gcgttgccta aatgagcaat
     2101 tgcgtttcta aatagtcttt tatttcttca acctccacta gaatagagct attaattggc
     2161 acgtagacgt ttgctgatgt cataatcttc aactcctatc gttatagata ataacgaaag
     2221 ataaaccaag gtgttaccag ctactacaag aaactaaata gaaatattaa cctgcacaac
     2281 aagataattt cgaaatatct ttatcaaagg ctagagctgc taactttaag ccttctgaca
     2341 ttgttagata aggcgctaaa gtatctttta aatcagctac ggtcaatcca aatttaacgg
     2401 ctaaggatgc tccataaata acttctcctg cattttcaga aacgatatga actcccaaaa
     2461 tcttctgtgt ttttctatca accacaagtt taaacacccc tgtcgtatta tgattgacaa
     2521 tcgctctagg aacattttct aatgacaata ccgctttttt tacttcgtat cctttttctt
     2581 tcgcttgttg ttgtgttaac ccaacagttg caaattgcgg actggtaaat gatactccag
     2641 gaactaccga taaatcgatt gctttattta acccaccaat tgcatttcct gctgcaattc
     2701 ctccttcata ggctgctaca tagacaaact gaggtcctaa tgtcacgtct cctgctgcat
     2761 aaatttttct attacttgtc tgagcaaaag catttatctt gatttcattg tttggcccaa
     2821 cttgaacgcc tgctgcgctc aagttcaata cttctgtatt cggttttctt cctgttccaa
     2881 ctagtagctc gtctgactca atgaccttat ttttgccgtt tacaataata tgaacttttt
     2941 taatatttcc gtcttgctct actcgttcat aagttgctcc ggaaatgagc tttattcctt
     3001 gttcgattaa agctttctcc attgcttcag aaatctctgg atcatactct tttaaaagtc
     3061 gtttgcttct ttgaataagg gtaacctcag aacccagatt gtggaagagc tgtcccagtt
     3121 ctcttccaat ataacccgat ccaataattg ttaatcgttt tggtactttt cttagttcaa
     3181 ggagggttgt gctagttaaa taatctactt ctttaagtcc agtaatacga ggtaagagtg
     3241 gagaagcacc cgttgcgatt aaaaaccgtt gggcagaata tgtttgccca ctaactgtca
     3301 cagtgttttc gtcaatgaat tttgcttctc ctttaattaa atcaaaacca tagtcgtcaa
     3361 ttaaattagt gtatttttgt ttgcgtaaat catcaactag ttcatttttt tgatcgacta
     3421 agcggtctaa ttctacttct cccgtagaag tgtgcaatcc ttcaaaaata tttacatgtg
     3481 ctgattgatt gatttctcca gctcgaagca gcgtttttga agggatacaa ccaatgttca
     3541 cacaggttcc gcctacagtt ccgcgttcaa tcatgcccac ctttgatcca tactcgactg
     3601 cttttatagc tgctgaaaaa gctgctccac cagaaccgat aatgagcaaa tcataatctt
     3661 ccttgttatt agtcatcacg cgtttttgaa caggtaactt ttctacttct tcgggctgat
     3721 aatttatttt tttaactgct tctatcgcgt tttctattgc atagtcgtct ggtaattgaa
     3781 ataccgcttc gctttgactg aaatctgctt tagcgttgag agctcccatg ctctcaagcg
     3841 ctttttctat atgtttttca cagccagtac aggtcattcc ttgaatgcgc attctaaatt
     3901 gattcatttt cctacccccg ttaattttct attaatactt ctatgatagg acacgcgtat
     3961 agttcttttt catctggaca tcttgctcgt aaatctttta gcatatattc tattctattc
     4021 aaattctcga tttttttttg aatttctctt tctttcttag agacaaattc aaacatacct
     4081 tcacaacgaa tgttgtcttt atctacaaca ccaagtaatt tataaatttc atttaaagaa
     4141 aagccaattt cttgtaggtg tttaatgaat tttactcgtt ttacatcttc ctctgaataa
     4201 actcgataac cggaattagt ccgatcgggt tctggtagta agttttttcg ttcgtaatat
     4261 cgaatggatt ccttatttac accacatttt tcagagaagg agctaataaa ataagccatg
     4321 ctatcacatc ctttttttaa ttataaacca tgtacttagg tacatgtcca accaaaaata
     4381 atacgaaggg ggg
//
LOCUS       DAZKNV010000210         4276 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.127, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000210 DAZKNV010000000
VERSION     DAZKNV010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.127"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            226..1704
                     /gene="msr(C)"
                     /locus_tag="ACG8M1_002985"
     CDS             226..1704
                     /gene="msr(C)"
                     /locus_tag="ACG8M1_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFQ0423594.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1751..2197
                     /locus_tag="ACG8M1_002986"
     CDS             1751..2197
                     /locus_tag="ACG8M1_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFQ0423595.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2396..2911)
                     /locus_tag="ACG8M1_002987"
     CDS             complement(2396..2911)
                     /locus_tag="ACG8M1_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0423596.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3028..4230
                     /locus_tag="ACG8M1_002988"
     CDS             3028..4230
                     /locus_tag="ACG8M1_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0423597.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1280 a          719 c          928 g         1349 t
ORIGIN      
        1 ataaattcaa aagacatgta taaacaacaa tttcatggat ggagtatgtc cattttttcg
       61 aacgacagta gaataggtga aagctatgac agatttggtg atttagtcat agttatttcg
      121 ttcagagtag gaaaagatgt gatgcagttt ttttgcaaac agatttttct gctctttttt
      181 agtatcgata attgttgttt tacatgaaat aggagtgtaa aacatatgga aaatttagca
      241 gtaaatataa caaatctaca agtcagcttt ggcaaccagc tagaactatc tattgattct
      301 cttcgtgtct atcagcaaga tcgtataggg atcataggag aaaatggtgt cggtaaatcg
      361 actttgctca aactaatagc cggtgaactt tttcccgatc atgggaaaat ccaaacagag
      421 atcaccttca actacctgcc tcaattaacc tatctcgctg aagcaaagga cctaaatttg
      481 gaattagcca gtcatttcca gttaagactg gaagaaactt cagagcggaa atggagcgga
      541 ggggaagaac gaaagatcga gttgatacgt cttctttctt cttatgaaca agggatgctt
      601 ctagacgagc caacaaccca tctagataga aaaagtattg atcgactgat tgaagagctt
      661 cgttattatt atggtacgct ggtttttgtt agtcatgatc gctattttct agatgagcta
      721 gcatcgaaaa tctgggaagt aaaagacgga gaaatccgag agttttcggg gaattatagt
      781 gcctatctca ctcaaaagga attggagaaa aagactcagc tacgagaagc agagtcgatc
      841 atgaaagaga aaaaacgatt ggaaaaatcg atccaagaaa agaaaaaaca agcggaaaag
      901 ttggaaaaag tgtccagtaa aaagaaaaag caacaaatca gactggatcg gttgtcttcc
      961 tctaaacaaa aagacagtgt acaaaaagcc atccaaaaga atgcgaaaac attagagaga
     1021 agactccaaa aaataggaga aacaaccaag ccgcagcaga tgaaacaaat ccgttttcca
     1081 gtaccaaaat ctcttgaact ccacagccgc tatcccatca tgggacaaaa tgtccaattg
     1141 gaaagaagtg ggagaacatt actggtaaat ggtgattttc agttttcttt aggtaaaaaa
     1201 atcgcgattg tcggtgaaaa tggttcaggt aagacaacct tattagaaca tatccgcaaa
     1261 caaggagaag gaatccttct ctctccgaaa gtaagctttc aagtatatca gcaaaagggt
     1321 tatcaaatga catctgaaga atccatcatt cgttttgtca tgagacaaac agagttttca
     1381 gaatcgcttg tccgtagttt gctgaatcac ttagggtttg ctcaggaaac tttgacgaaa
     1441 ccgttatgta cattaagtgg gggagaagcg acccgtctga cgattgcttt gctttttact
     1501 aagccaagta atgtgttgct gttagatgaa ccgactaatt ttattgatat ggcaacgatc
     1561 gaagctttag agaagctaat gcaaatatat ccgggaacga ttttgtttac ttctcatgat
     1621 tcttactttg tcgagcgtac ggctgatgaa gtttatgaaa taaaagggca gaaaataaaa
     1681 aaagtactta cgagaaattt ttaaatgtgc tacgatgatt ttcgtgacaa atttaaagga
     1741 gtggtacaga ttgcctacaa ataaaaaaga aggaataatt tttacaacaa tgatgtgttt
     1801 tttgatggtc ttggggatga gcgcgtataa tttatggctg catcaagatc ttcatttatc
     1861 aagtttgttg attggtctag tgcctggatt cgtggtggct ttcattttgg atgtcttcat
     1921 catcggtgtg ctggcgaaaa aaattgcctt taaactacca gtaaatccag aaagcaaggt
     1981 ccaaatgatc ttaactattt catgcttgat ggttttagga atggtgacat gtatgtcttt
     2041 attcggtgtg atcatggaac aaggaatacc tgatcaatta ttctctgctt atatgaatgc
     2101 ttggaaaatg aatgtgattg ccgctttacc gttgcagttg atcatcgttg gcccgctttc
     2161 aagaagtgtg ctaaaagcaa ttcaaagtaa tgaatgatgg aacactgtta tttgaaaaaa
     2221 ggccttggca tgctttttgt catagtctct tgaatgcagt tctagaaaaa tagtgatccg
     2281 aacgataggt tttggcctgt cgttcggatc gctttttctt ttccaactgt attgctcttt
     2341 tattgaagat aatttgctct tcaatagata tttctagaaa ggttctgttt atcccttact
     2401 caaaaaactg ctgcatttgt tctcttactt gctgacacca ttggagttcc tgctgacaaa
     2461 gcataattct gcgctggatc acaacataac gtccaaattc ttgtttcttg tctagcgaga
     2521 ggtcattcaa ttttttttga tttttttgca tgattttgtt cagctgttgt tctctagtga
     2581 atagcagtcc agtagctgtt gttttatcga gcgtcgaaaa agcatagatt tttgctagaa
     2641 attcatcttt ttgcgtagga gcgggagttt cctctttgat ccattcctct acaagagcac
     2701 gtccttcatc agtcaagtgg tagatctttt tttgagagtg ctcgtctttg tccaaaacgg
     2761 tcacataacc ctgctggtct aacttggcaa gcgttgtata gatctgactg tgatgggctt
     2821 cccaaaaaat tgtgatcagc tgcttcaatt catacccaga acgtggtttg gataaaagca
     2881 cgcataataa tatataggct aaagtattca taaaaatcct acctctcgtc ttattttctt
     2941 tattatatca cagtaaagtt tccacgtttt acatgtgcat attgacatgt aaaataaatc
     3001 atgtatgatg ctaatagaga gaaagggatg gaaatattgg agaatcaaat agatatacaa
     3061 gaacaaacaa atgaagaaac aaaggggaaa agttcagcgc tagttgtagc agctacctgt
     3121 atgatcgctt ttatgggagt gggtctagta gacccaatct taaaaacgat tgctgcacag
     3181 ttaaacgcta cgccagctga aacgaccctg ttatttacta gttacatgtt agtcactggt
     3241 gtggtgatgc tatttacagg tttcttatct agtcggatcg gtttgaaaaa aacattgatg
     3301 acaggattgt ttatcatcgt tgtattcgct ggtcttggcg gattatctgg gaatatcgga
     3361 atgctgattg ggttacgtgc cggctggggt gtcgggaatg ctttatttgt ctctactgct
     3421 ttagcaacga tcgtcagtat tttagttggt aacacagaaa aagcaatcat gatgtatgaa
     3481 gcagcacttg gctgcggaat ggctgttggc cctctagtcg gtggggtctt gggcagtggt
     3541 tcatggcgtt atccattttt tggggtagca tttttgatgt tttgcggttt tatagcccta
     3601 gcggtacttt tacctgaaac tgagaaacca aagagaaaag taggcctttg ggaaggtgtc
     3661 aaagcgttaa gcaatcataa acttcgttca gttggactaa tcgcattgtt atataatttc
     3721 ggattcttta ctttacttgc gtatgcgcca tttttattga ttggctattc tgaattagaa
     3781 gtcggttttg tattttttgg ctggggtgtg cttctggcta ttgcttcgat tttcgttgca
     3841 ccggctcttg agcggaagtt tacgacttat cggacaattt tagcagcatt tgtcttattc
     3901 attatttgtt tgctgttatt aggagctgga acttctatgc cagtccttgt accgatcagc
     3961 attgtgttag caggattttt ccaaggaatt atcaatacac tgttgacgac gattgctatg
     4021 gaaataccag gtctgcaacg aaacgttgct tcgtccagct atagttttgt ccgctttttc
     4081 ggtggagctt tagcaccatt tattgcaggt gtgattggtg aacatattgg tgaaagctat
     4141 gcgttttatt ttgcaggtgc cattgttctt atcagtgtat gttgtatcat ttatcaccgt
     4201 aattattttg ctacaaatga agaagaataa gaaatcagag gttgtgaaaa agctgtcctg
     4261 catcaagtca taagaa
//
LOCUS       DAZKNV010000211         3008 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.137, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000211 DAZKNV010000000
VERSION     DAZKNV010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.137"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            266..1234
                     /locus_tag="ACG8M1_002989"
     CDS             266..1234
                     /locus_tag="ACG8M1_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFQ0423598.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1227..2258
                     /gene="vanA"
                     /locus_tag="ACG8M1_002990"
     CDS             1227..2258
                     /gene="vanA"
                     /locus_tag="ACG8M1_002990"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFQ0423599.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2264..2872
                     /locus_tag="ACG8M1_002991"
     CDS             2264..2872
                     /locus_tag="ACG8M1_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFQ0423600.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          896 a          571 c          725 g          816 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa ggaggtccta agagatgtat
       61 ataatttttt aggaaaatct caaggttatc tttacttttt cttaggaaat taacaattta
      121 atattaagaa acggctcgtt cttacacggt agacttaata ccgtaagaac gagccgtttt
      181 cgttcttcag agaaagattt gacaagatta ccattggcat ccccgtttta tttggtgcct
      241 ttcacagaaa gggttggtct taattatgaa taacatcggc attactgttt atggatgtga
      301 gcaggatgag gcagatgcat tccatgctct ttcgcctcgc tttggcgtta tggcaacgat
      361 aattaacgcc aacgtgtcgg aatccaacgc caaatccgcg cctttcaatc aatgtatcag
      421 tgtgggacat aaatcagaga tttccgcctc tattcttctt gcgctgaaga gagccggtgt
      481 gaaatatatt tctacccgaa gcatcggctg caatcatata gatacaactg ctgctaagag
      541 aatgggcatc actgtcgaca atgtggcgta ctcgccggat agcgttgccg attatactat
      601 gatgctaatt cttatggcag tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca
      661 tgatttcagg ttggacagcg accgtggcaa ggtactcagc gacatgacag ttggtgtggt
      721 gggaacgggc cagataggca aagcggttat tgagcggctg cgaggatttg gatgtaaagt
      781 gttggcttat agtcgcagcc gaagtataga ggtaaactat gtaccgtttg atgagttgct
      841 gcaaaatagc gatatcgtta cgcttcatgt gccgctcaat acggatacgc actatattat
      901 cagccacgaa caaatacaga gaatgaagca aggagcattt cttatcaata ctgggcgcgg
      961 tccacttgta gatacctatg agttggttaa agcattagaa aacgggaaac tgggcggtgc
     1021 cgcattggat gtattggaag gagaggaaga gtttttctac tctgattgca cccaaaaacc
     1081 aattgataat caatttttac ttaaacttca aagaatgcct aacgtgataa tcacaccgca
     1141 tacggcctat tataccgagc aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg
     1201 tttggatttt gaaaggagac aggagcatga atagaataaa agttgcaata ctgtttgggg
     1261 gttgctcaga ggagcatgac gtatcggtaa aatctgcaat agagatagcc gctaacatta
     1321 ataaagaaaa atacgagccg ttatacattg gaattacgaa atctggtgta tggaaaatgt
     1381 gcgaaaaacc ttgcgcggaa tgggaaaacg acaattgcta ttcagctgta ctctcgccgg
     1441 ataaaaaaat gcacggatta cttgttaaaa agaaccatga atatgaaatc aaccatgttg
     1501 atgtagcatt ttcagctttg catggcaagt caggtgaaga tggatccata caaggtctgt
     1561 ttgaattgtc cggtatccct tttgtaggct gcgatattca aagctcagca atttgtatgg
     1621 acaaatcgtt gacatacatc gttgcgaaaa atgctgggat agctactccc gccttttggg
     1681 ttattaataa agatgatagg ccggtggcag ctacgtttac ctatcctgtt tttgttaagc
     1741 cggcgcgttc aggctcatcc ttcggtgtga aaaaagtcaa tagcgcggac gaattggact
     1801 acgcaattga atcggcaaga caatatgaca gcaaaatctt aattgagcag gctgtttcgg
     1861 gctgtgaggt cggttgtgcg gtattgggaa acagtgccgc gttagttgtt ggcgaggtgg
     1921 accaaatcag gctgcagtac ggaatctttc gtattcatca ggaagtcgag ccggaaaaag
     1981 gctctgaaaa cgcagttata accgttcccg cagacctttc agcagaggag cgaggacgga
     2041 tacaggaaac ggcaaaaaaa atatataaag cgctcggctg tagaggtcta gcccgtgtgg
     2101 atatgttttt acaagataac ggccgcattg tactgaacga agtcaatact ctgcccggtt
     2161 tcacgtcata cagtcgttat ccccgtatga tggccgctgc aggtattgca cttcccgaac
     2221 tgattgaccg cttgatcgta ttagcgttaa aggggtgata agcatggaaa taggatttac
     2281 ttttttagat gaaatagtac acggtgttcg ttgggacgct aaatatgcca cttgggataa
     2341 tttcaccgga aaaccggttg acggttatga agtaaatcgc attgtaggga catacgagtt
     2401 ggctgaatcg cttttgaagg caaaagaact ggctgctacc caagggtacg gattgcttct
     2461 atgggacggt taccgtccta agcgtgctgt aaactgtttt atgcaatggg ctgcacagcc
     2521 ggaaaataac ctgacaaagg aaagttatta tcccaatatt gaccgaactg agatgatttc
     2581 aaaaggatac gtggcttcaa aatcaagcca tagccgcggc agtgccattg atcttacgct
     2641 ttatcgatta gacacgggtg agcttgtacc aatggggagc cgatttgatt ttatggatga
     2701 acgctctcat catgcggcaa atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt
     2761 gcgctccatc atggaaaaca gtgggtttga agcatatagc ctcgaatggt ggcactatgt
     2821 attaagagac gaaccatacc ccaatagcta ttttgatttc cccgttaaat aaacttttaa
     2881 ccgttgcacg gacaaactat ataagctaac tctttcggca ggaaacccga cgtatgtaac
     2941 tggttcttag ggaatttata tatagtagat aacccgtggt gctagttaat tttaatatcc
     3001 taaagaat
//
LOCUS       DAZKNV010000212         2077 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.152, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000212 DAZKNV010000000
VERSION     DAZKNV010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.152"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..341)
                     /locus_tag="ACG8M1_002992"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACG8M1_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACG8M1_002993"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACG8M1_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1055..1345)
                     /locus_tag="ACG8M1_002994"
     CDS             complement(1055..1345)
                     /locus_tag="ACG8M1_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0423601.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..2077)
                     /locus_tag="ACG8M1_002995"
                     /pseudo
     CDS             complement(1553..2077)
                     /locus_tag="ACG8M1_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321659.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          590 a          385 c          303 g          799 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt gcttcgtcta
     1681 atttcttttg tgtatctgtt aactgatttc tacatttgtt ttttcttgtg tcagtgttgc
     1741 gatttgttga ttcaaaccat ttacagtatt ttgtaattct gaaagttttg cttgtgcttc
     1801 ttgtagtctt gctgtccaat ctgcattcag atgattgatt tcatcatttt tttggttgat
     1861 ctcatctagt ttgacattga tttcattttg tttgctttgt agttgtgcat ccttgctgac
     1921 taattgactt tctaagtttt gtttttctgc tgccgattga tttttttggt tttctaattc
     1981 atttactttt gtttggtatt cttggacatc tgcctttgaa tcttgcaatg tctgttcttt
     2041 ttgtgctagt cgagcggtaa gatctgtaat cgcttgc
//
LOCUS       DAZKNV010000213         2057 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.153, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000213 DAZKNV010000000
VERSION     DAZKNV010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.153"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            197..892
                     /gene="vanR-A"
                     /locus_tag="ACG8M1_002996"
     CDS             197..892
                     /gene="vanR-A"
                     /locus_tag="ACG8M1_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFQ0423602.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            870..2039
                     /gene="vanS"
                     /locus_tag="ACG8M1_002997"
     CDS             870..2039
                     /gene="vanS"
                     /locus_tag="ACG8M1_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFQ0423603.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRGSVAKF"
BASE COUNT          690 a          387 c          441 g          539 t
ORIGIN      
        1 aatgggcaat atttttaaag aagaaaagga aactataaaa tattaacagc ctcctagcga
       61 tgccgaaaag ccctttgata aaaaaagaat catcatctta agaaattctt agtcatttat
      121 tatgtaaatg cttataaatt cggccctata atctgataaa ttattaaggg caaacttatg
      181 tgaaagggtg ataactatga gcgataaaat acttattgtg gatgatgaac atgaaattgc
      241 cgatttggtt gaattatact taaaaaacga gaattatacg gttttcaaat actataccgc
      301 caaagaagca ttggaatgta tagacaagtc tgagattgac cttgccatat tggacatcat
      361 gcttcccggc acaagcggcc ttactatctg tcaaaaaata agggacaagc acacctatcc
      421 gattatcatg ctgaccggga aagatacaga ggtagataaa attacagggt taacaatcgg
      481 cgcggatgat tatataacga agccctttcg cccactggag ttaattgctc gggtaaaggc
      541 ccagttgcgc cgatacaaaa aattcagtgg agtaaaggag cagaacgaaa atgttatcgt
      601 ccactccggc cttgtcatta atgttaacac ccatgagtgt tatctgaacg agaagcagtt
      661 atcccttact cccaccgagt tttcaatact gcgaatcctc tgtgaaaaca aggggaatgt
      721 ggttagctcc gagctgctat ttcatgagat atggggcgac gaatatttca gcaagagcaa
      781 caacaccatc accgtgcata tccggcattt gcgcgaaaaa atgaacgaca ccattgataa
      841 tccgaaatat ataaaaacgg tatggggggt tggttataaa attgaaaaat aaaaaaaacg
      901 actattccaa actagaacga aaactttaca tgtatatcgt tgcaattgtt gtggtagcaa
      961 ttgtattcgt gttgtatatt cgttcaatga tccgagggaa acttggggat tggatcttaa
     1021 gtattttgga aaacaaatat gacttaaatc acctggacgc gatgaaatta tatcaatatt
     1081 ccatacggaa caatatagat atctttattt atgtggcgat tgtcattagt attcttattc
     1141 tatgtcgcgt catgctttca aaattcgcaa aatactttga cgagataaat accggcattg
     1201 atgtacttat tcagaacgaa gataaacaaa ttgagctttc tgcggaaatg gatgttatgg
     1261 aacaaaagct caacacatta aaacggactc tggaaaagcg agagcaggat gcaaagctgg
     1321 ccgaacaaag aaaaaatgac gttgttatgt acttggcgca cgatattaaa acgcccctta
     1381 catccattat cggttatttg agcctgcttg acgaggctcc agacatgccg gtagatcaaa
     1441 aggcaaagta tgtgcatatc acgttggaca aagcgtatcg actcgaacag ctaatcgacg
     1501 agttttttga gattacacgg tataacctac aaacgataac gctaacaaaa acgcacatag
     1561 acctatacta tatgctggtg cagatgaccg atgaatttta tcctcagctt tccgcacatg
     1621 gaaaacaggc ggttattcac gcccccgagg atctgaccgt gtccggcgac cctgataaac
     1681 tcgcgagagt ctttaacaac attttgaaaa acgccgctgc atacagtgag gataacagca
     1741 tcattgacat taccgcgggc ctctccgggg atgtggtgtc aatcgaattc aagaacactg
     1801 gaagcatccc aaaagataag ctagctgcca tatttgaaaa gttctatagg ctggacaatg
     1861 ctcgttcttc cgatacgggt ggcgcgggac ttggattggc gattgcaaaa gaaattattg
     1921 ttcagcatgg agggcagatt tacgcggaaa gcaatgataa ctatacgacg tttagggtag
     1981 agcttccagc gatgccagac ttggttgata aaaggagggg ttctgttgca aagttttaaa
     2041 taaagaataa aatccct
//
LOCUS       DAZKNV010000214         1175 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.181, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000214 DAZKNV010000000
VERSION     DAZKNV010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.181"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            47..439
                     /locus_tag="ACG8M1_002998"
     CDS             47..439
                     /locus_tag="ACG8M1_002998"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0423604.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            440..>1175
                     /gene="aac(6')-Ie"
                     /locus_tag="ACG8M1_002999"
     CDS             440..>1175
                     /gene="aac(6')-Ie"
                     /locus_tag="ACG8M1_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HFQ0423605.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYN"
BASE COUNT          477 a           94 c          208 g          396 t
ORIGIN      
        1 aacattgtat agcattttac acaggagtct ggacttgact gagtttatgg aagaagtttt
       61 aattgatgat aatatggttt ttgatattga taatttaaaa ggatttctta atgataccag
      121 ttcatttggg tttatagcta aagaaaataa taaaattata ggatttgcat attgctatac
      181 acttttaaga cctgatggaa aaacaatgtt ttatttacac tcaataggaa tgttacctaa
      241 ctatcaagac aaaggttatg gttcaaaatt attatctttt attaaggaat attctaaaga
      301 gattggttgt tctgaaatgt ttttaataac tgataaaggt aatcctagag cttgccatgt
      361 atatgaaaaa ttaggtggta aaaatgatta taaagatgaa atagtatatg tatatgatta
      421 tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa atatgtataa gaactttaat
      481 agatgatgat tttcctttga tgttaaaatg gttaactgat gaaagagtat tagaatttta
      541 tggtggtaga gataaaaaat atacattaga atcattaaaa aaacattata cagagccttg
      601 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
      661 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
      721 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
      781 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
      841 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
      901 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
      961 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     1021 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     1081 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     1141 aaaaggttat gcaaaagaaa aagcaatata taatt
//
LOCUS       DAZKNV010000215         1122 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.185, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000215 DAZKNV010000000
VERSION     DAZKNV010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.185"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            111..194
                     /locus_tag="ACG8M1_003000"
     CDS             111..194
                     /locus_tag="ACG8M1_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFQ0423606.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="ACG8M1_003001"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="ACG8M1_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFQ0423607.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1001..>1122
                     /locus_tag="ACG8M1_003002"
     CDS             1001..>1122
                     /locus_tag="ACG8M1_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine methyltransferase"
                     /protein_id="HFQ0423608.1"
                     /translation="MSKYCLFLIVIYYLTGGNNSMSRFFKFGKLHVTKGNGDKL"
BASE COUNT          424 a          177 c          176 g          345 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 cacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta tt
//
LOCUS       DAZKNV010000216         1118 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.186, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000216 DAZKNV010000000
VERSION     DAZKNV010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.186"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..999
                     /locus_tag="ACG8M1_003003"
                     /note="aph(2'')-Ia"
     CDS             <1..999
                     /locus_tag="ACG8M1_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFQ0423609.1"
                     /translation="YQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRAYKD"
BASE COUNT          480 a           82 c          187 g          369 t
ORIGIN      
        1 taccaaaaat ctggttttag aattattgaa gatttgccag aacatgaatt acacgagggc
       61 aaaaaagaag attgttattt aatggaatat agatatgatg ataatgccac aaatgttaag
      121 gcaatgaaat atttaattga gcattacttt gataatttca aagtagatag tattgaaata
      181 atcggtagtg gttatgatag tgtggcatat ttagttaata atgaatacat ttttaaaaca
      241 aaatttagta ctaataagaa aaaaggttat gcaaaagaaa aagcaatata taatttttta
      301 aatacaaatt tagaaactaa tgtaaaaatt cctaatattg aatattcgta tattagtgat
      361 gaattatcta tactaggtta taaagaaatt aaaggaactt ttttaacacc agaaatttat
      421 tctactatgt cagaagaaga acaaaatttg ttaaaacgag atattgccag ttttttaaga
      481 caaatgcacg gtttagatta tacagatatt agtgaatgta ctattgataa taaacaaaat
      541 gtattagaag agtatatatt gttgcgtgaa actatttata atgatttaac tgatatagaa
      601 aaagattata tagaaagttt tatggaaaga ctaaatgcaa caacagtttt tgagggtaaa
      661 aagtgtttat gccataatga ttttagttgt aatcatctat tgttagatgg caataataga
      721 ttaactggaa taattgattt tggagattct ggaattatag atgaatattg tgattttata
      781 tacttacttg aagatagtga agaagaaata ggaacaaatt ttggagaaga tatattaaga
      841 atgtatggaa atatagatat tgagaaagca aaagaatatc aagatatagt tgaagaatat
      901 tatcctattg aaactattgt ttatggaatt aaaaatatta aacaggaatt tatcgaaaat
      961 ggtagaaaag aaatttataa aagggcttat aaagattgat tatataatat atgaaaagct
     1021 attataaaag acattagtat taaatagttt aaaaaaatga aaaataataa aggaagtgag
     1081 tcaagtccag actcctgtgt aaaatgctat acaatgtt
//
LOCUS       DAZKNV010000217          897 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3483
            SAMEA115706752-rid22569993.guided.196, whole genome shotgun
            sequence.
ACCESSION   DAZKNV010000217 DAZKNV010000000
VERSION     DAZKNV010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706752
            Sequence Read Archive: ERR13196486
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287761.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287761.1
            Genome Coverage       :: 121x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:05:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 39 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706752-rid22569993.guided.196"
                     /isolate="VRE3483"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            284..832
                     /gene="aac(6')"
                     /locus_tag="ACG8M1_003004"
     CDS             284..832
                     /gene="aac(6')"
                     /locus_tag="ACG8M1_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFQ0423610.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          316 a          134 c          185 g          262 t
ORIGIN      
        1 tatggccttt ttacttttac acaattatac ggactttatc gtttttttta aagcaaaaga
       61 taatctatat catgatgaac aaacagagtt ttttcctcca attgatggct ttcctgatct
      121 ttcctatttt gaataaagtg tttctgtata atttttttat tttataagta agataaataa
      181 tgaaagaata gagatactga ttggtagcta aagatttttg agcgagaaca tttcgttttt
      241 tcaaaaggac tgttagaata agcaagaaca agggggaaga cgtatgataa tcagtgaatt
      301 tgaccgtaat aatccagtat tgaaagatca gctttctgat ttactgagac tgacttggcc
      361 ggaagaatat ggagacagct cggcagaaga agtagaagaa atgatgaatc cagaacgaat
      421 cgcggtagca gcggtagacc aagatgagtt agtaggattt attggtgcaa tccctcaata
      481 cggtatcaca ggttgggaat tgcatccatt agttgtagaa agctcccgac gaaagaacca
      541 aataggtact cgattagtca attacttaga aaaagaagta gcttccagag gaggaatcac
      601 gatttattta ggtacggatg atttagacca tggaacaacg ttaagtcaaa cggacctgta
      661 tgagcataca tttgataaag tggcttccat ccagaacctt cgtgaacatc cgtatgaatt
      721 ctatgaaaaa ttaggttata aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa
      781 accggatatt tggatggcaa aaacgattat tcctcgacca aattctcaat aataaaaaga
      841 ggttgtgaca gaagtaatca gcttcaagaa ataagaagga atttacgaaa attactt
//
